ライフサイエンスコーパス: limitation

1 , which affect the strength of regional iron limitation.

2 ity-weighted survival curves to address this limitation.

3 rates and blood doses, exposing a potential limitation.

4 olved in overcoming host-induced nutritional limitation.

5 ter conditions were mainly due to a stomatal limitation.

6 re highly expressed under conditions of iron-limitation.

7 country, so the single country setting is a limitation.

8 Here, we present new tools to overcome these limitations.

9 douts, should resolve several of the current limitations.

10 shown a great potential in overcoming these limitations.

11 thods used to make these estimates have some limitations.

12 ta, partially attributable to methodological limitations.

13 Screening methods are effective but have limitations.

14 aft versus host disease (GVHD) but they have limitations.

15 tion-metal fluorides, and it overcomes these limitations.

16 al alternative therapeutic options and their limitations.

17 down at this scale due to inherent physical limitations.

18 tiviruses, a technique that presents diverse limitations.

19 attern arises almost entirely from technical limitations.

20 f these strategies, however, has substantial limitations.

21 a plant focus, but highlight also potential limitations.

22 nexplored because of additional experimental limitations.

23 application in the Arctic due to a series of limitations.

24 ver, each data source has its own biases and limitations.

25 te different cultural practices and resource limitations.

26 mains poorly understood due to technological limitations.

27 ving FRAP measurements beyond these previous limitations.

28 xisting approaches may each have some severe limitations.

29 ow environmental pressures may exploit these limitations.

30 ning Treatment (POLST) to document treatment limitations.

31 gan Sharing (UNOS), the OPTN contractor, has limitations.

32 igh and was limited by imprecision and study limitations.

33 ft cold-atom studies beyond such terrestrial limitations.

34 d host has not been studied due to technical limitations.

35 vo screens to illustrate their strengths and limitations.

36 y in patients with Crohn's disease (CD) have limitations.

37 sed allocation system identified challenging limitations.

38 laced on how to model the transition between limitations accurately as drivers change.

39 ition to usual care for people with mobility limitations admitted to aged care and neurological rehab

40 overload, such as haemochromatosis, or iron limitation anaemias(2).

41 with distance vision, social function, role limitation and dependency of the socioeconomic subscale.

42 rimary outcomes were prevalence of treatment limitation and its influence on severity-adjusted ICU mo

43 theory with empirical observations of oxygen limitation and provides a formal, quantitative framework

44 disease, moderate-severe expiratory airflow limitation and radiologically determined bronchiectasis/

45 ative 3D organ structure due to its sampling limitation and shallow imaging depth.

46 ost-derived nutrients, which may alleviate N limitation and stimulate productivity in warming tundra.

47 S counterstrategies to combat CP-mediated Zn limitation and the in vivo relevance of CP-GAS interacti

48 ely related to growing slowly under nutrient limitation and to resistance to microbial decomposition.

49 ls rather than observed cells to avoid these limitations and balances the performance between major a

50 Finally, we review the current limitations and challenges for the construction of hybri

51 tion, we tested strategies to overcome these limitations and challenges.

52 n challenging to study due to both technical limitations and ethical restrictions.

53 To overcome these limitations and facilitate the investigation of miRNA fu

54 g cells differ in their response to nutrient limitations and how this impacts invasion of the metapop

55 The current methods in use suffer many limitations and need high logistical and laboratory requ

56 c analysis and information flow, its current limitations and potential cardiovascular applications.

57 circumvent aforementioned genetic screening limitations and present methods for a multiplex CRISPR/C

58 troduced here can help physicians understand limitations and risks as well as the potential benefits

59 To circumvent these limitations and study the role of patrolling monocytes i

60 ch and address its possibilities and current limitations and the broader range of Parkinson disease f

61 with functions that overcome most of the EAI limitations and to determine whether patient behaviour a

62 nt in a Swiss ICU has some kind of treatment limitation, and this most probably affects the severity-

63 Considering each therapy's advantages, limitations, and challenges is necessary when choosing b

64 his review summarizes key concepts, clinical limitations, and important opportunities for research.

65 ach tool comes with its own capabilities and limitations, and major efforts have broadened their edit

66 ve variable primary end points, study design limitations, and only short-term follow-up data.

67 , 1.66-4.24]; P < .001) but not with airflow limitation (aOR, 1.07 [95% CI, .71-1.62]; P = .745).

68 at, similar to mammals, Drosophila uses iron limitation as an immune defense mechanism mediated by co

69 itched from reaction limitation to transport limitation as the floodplain length increased, and remov

70 omic analysis revealed adaptations to oxygen-limitation as well as pathways for mixed-acid fermentati

71 stems from biological rather than technical limitations as most synthetic lethal phenotypes are stro

72 hile this likely reflects both technological limitations as well as the fact that well-known genes te

73 s, critical evaluation of potentialities and limitations as well as the outline of further developmen

74 However, limitations associated with anti-VEGF medications requir

75 We find that vegetation N limitation becomes stronger despite the increased availa

76 Dispersal limitation, biotic interactions, and environmental filte

77 ncy and the new sequencing chemistry removes limitations bound by sequence-by-ligation chemistry of I

78 s of WUE(i) under short- and long-term water limitations, but showed a significant negative relations

79 ine learning study to date, we overcome this limitation by capitalizing on the spatial resolution of

80 on Electrocoagulation (ACAIE) overcomes this limitation by cathodically generating H(2)O(2) in situ.

81 Dual-energy CT may overcome this limitation by improving the conspicuity of the contrast

82 Peptidomimetics can respond to peptide limitations by displaying higher metabolic stability, go

83 his work presents a means to eliminate these limitations by introducing an active scatterer in a mech

84 physical domain (physical functioning, role limitations caused by physical health problems) remained

85 describing how shifts from nutrient to light limitation control primary productivity in lake ecosyste

86 A theoretical limitation could be the reinnervation, that naturally gr

87 port for the strong negative effects of food limitation during the nestling rearing period on urban b

88 However, methodological limitations (e.g. in MS of phosphopeptides, or antibodie

89 rming reactions, these have numerous crucial limitations, especially for industrial-scale application

90 Lack of dynamic plasticity is a significant limitation for artificial systems that must robustly ope

91 dition to counteracting hepcidin-driven iron limitation for erythropoiesis, we found that the combina

92 ime-consuming, and constitutes a significant limitation for the development of single-use and wearabl

93 A limitation for the treatment of unresectable cholangioca

94 Dispersal limitation for tropical bryophytes flies in the face of

95 ils on the benefit of the IDAs and perceived limitations for each system.

96 In contrast with theory predicting limitation from a single limiting factor, the linear J(C

97 This limitation has led to models of early life in which the

98 inting, and electron-beam lithography, whose limitations have hampered rapid innovations and broad ap

99 n identified as neurotransmitters, technical limitations have precluded a full metabolomic analysis o

100 To resolve this limitation, here we employ a new nonparametric statistic

101 To address this limitation, here we overexpressed, purified, and charact

102 To overcome this limitation, here we report an improved SPS/ETD workflow

103 We tested core predictions of the food limitation hypothesis using a controlled experiment that

104 ody species, we present a meta-analysis of P limitation impacts on plant growth, physiological, and m

105 Here we show that the limitations imposed by fluid instabilities with thermall

106 than one watt per square metre, owing to the limitations imposed by interfacial effects-as seen in ch

107 d endogenous proteomic responses to cysteine limitation in Mycobacterium smegmatis using mass spectro

108 at this oversight may be associated with the limitation in one's mental capacity to simultaneously re

109 A key limitation in our understanding of the cause and consequ

110 However, every single method has its limitation in terms of polarity and molecular weight of

111 A current limitation in the advancement of live-cell single-molecu

112 A primary limitation in the use of pluripotent stem cell-derived c

113 age of NB moieties, leading to unpredictable limitations in control over system properties (e.g., rap

114 and potential strategies to address current limitations in CRC screening.

115 udies assessing the prevalence and impact of limitations in design, conduct, analysis, and reporting

116 ced ejection fraction (HFrEF) exhibit severe limitations in exercise capacity ( VO2 peak).

117 w affinities of GBP-glycan interactions, and limitations in existing binding assays.

118 to characterize at a structural level due to limitations in existing structure determination methods.

119 neural circuitry, the ethical and technical limitations in exploring neural underpinnings limit our

120 rent iterations of brain organoids also have limitations in faithfully recapitulating the in vivo pro

121 active area with low reproducibility due to limitations in lithography, where sensing nanosized rare

122 These findings had limitations in potential reverse causation and residual

123 lower levels of Cd19 expression, suggesting limitations in preclinical animal models of neurotoxicit

124 xplain how the brain copes with its capacity limitations in real-time environments and may lead the w

125 been proposed in theory but blocked by data limitations in the United States.

126 but also stereochemical aspects, scope, and limitations, in particular side reactions, are discussed

127 Key study limitations include a paucity of longitudinal studies (n

128 Key limitations include focusing just on the sickest subset

129 Limitations include high risk of bias and moderate to ve

130 Study limitations include lack of data on access to antiretrov

131 Potential limitations include nonrandom sampling, the focus on a s

132 Limitations include substantial uncertainty due to the l

133 Study limitations include that it was not possible to assess t

134 Limitations include the availability of a single weight

135 Key limitations include the descriptive nature of the analys

136 Limitations include the potential for unmeasured confoun

137 Major limitations include the use of echo Doppler to estimate

138 Study limitations include underrepresentation of women and a l

139 The study's main limitations included a rather small proportion of women

140 Limitations included possible underrepresentation of hom

141 Limitations included the inability to obtain all SIVH re

142 Study limitations included the short evaluation period (24 mon

143 These drugs have significant limitations, including the need for subcutaneous injecti

144 ting membrane distillation overcomes several limitations inherent in conventional membrane distillati

145 However, there are complexities and manifest limitations inherent in translating complex human diseas

146 empirical financial data, due to regulatory limitations, intellectual property and privacy control,

147 This limitation is particularly troublesome when evaluating g

148 A limitation is that, owing to the nature of lipoprotein m

149 Another limitation is the side effects associated with the treat

150 In addition to confirming that P limitation is widespread in tropical regions, our study

151 ng technologies and overcoming their current limitations is provided.

152 One strategy used to overcome these limitations is the decoration of the outer surface of gr

153 This phenomenon, which we call 'information limitation', is likely to be widespread in real ecologic

154 Specifically, mass-transport limitations lead to large concentration gradients in the

155 iency anemia (IDA) in patients with CKD have limitations, leading to persistent challenges in the det

156 elimination is impracticable due to resource limitations, less ambitious implementations of this comb

157 The kinetic limitation manifests not only as the kinetic capacity lo

158 Yet, O(2) limitation may differentially impact kinetic or thermody

159 Nutrient limitations may also affect the maintenance of body mass

160 factors influence g(m) , (iii) the technical limitation of estimating g(m) , which cannot be directly

161 histochemical investigation, overcoming the limitation of field studies, where optimal pre-analytica

162 us for low-abundance proteins, a significant limitation of many multiplex MS methods.

163 The main limitation of our analyses, in common with other studies

164 A limitation of our study is that the included EDs are not

165 The main limitation of our study is the potential for misclassifi

166 t the microwire biosensor overcomes the time limitation of permanently implanted biosensors and that

167 The limitation of plasticity in the adult brain impedes func

168 cations for how ecologists consider nutrient limitation of primary consumers in ecosystems globally.

169 One limitation of protein-mediated transcription roadblockin

170 IDO/TDO expressing tumors would overcome the limitation of single IDO or TDO targeting agents and con

171 Cas9 orthologs can help to overcome the size limitation of SpCas9.

172 ignal amplification methods can overcome the limitation of SPR methods for detection of small molecul

173 A significant limitation of standard MRI sequences is that the ventral

174 A potential limitation of the BFPP assay is the absence of fungal ta

175 ycocerosate-dependent growth compromise upon limitation of the corresponding substrate.

176 ible with the OAE duration being extended by limitation of the global silicate weathering flux.

177 A main limitation of the present study is the observational des

178 A limitation of the study is lack of data on population pr

179 A limitation of the study is that 27% of baseline particip

180 A limitation of this project is that our consensus meeting

181 One potential limitation of using HIEs for innate immune studies is th

182 nsors, e.g. for studying mechanical response/limitations of aerospace composite structures.

183 Regulations tailored to the nature and limitations of AI are currently in development and, when

184 degenerative disease has been impeded by the limitations of available animal models in reproducing ma

185 ransfusion events is often restricted by the limitations of bacterial culture in terms of time requir

186 In our quest to circumvent the limitations of chemotherapy and photodynamic therapy, we

187 The limitations of classical drugs have spurred the developm

188 We discuss the strengths and limitations of commonly used computational approaches fo

189 is for manufacturing methods that can bypass limitations of conventional 3D micro/nanofabrication.

190 th histology and may be used to overcome the limitations of conventional bread-loaf histology.

191 ion outcomes is poorly understood because of limitations of conventional SES measures.

192 Due to the limitations of conventional therapies and inevitable eme

193 ometry (MS)-based methods could overcome the limitations of current detection techniques.

194 Owing to limitations of current diagnostic tests (i.e., poor sens

195 el electrocatalysts to potentially break the limitations of current materials, enhancing the device p

196 reviewed with a focus on the advantages and limitations of current T(1) contrast agents and the pote

197 Applicability of the search tools and limitations of databases were discussed.

198 ed in architectural complexity, owing to the limitations of extrusion-based 3D printing techniques.

199 ase have been variable, in part owing to the limitations of fetal tissue as a cell source, relating t

200 atient complexities and exposed the inherent limitations of generic therapies for patient treatment.

201 dividualized HbA(1c) targets, we examine the limitations of HbA(1c), and we consider alternatives for

202 extensively studied in order to overcome the limitations of homogeneous Fenton processes.

203 apy an attractive approach to circumvent the limitations of immunotherapy alone.

204 thods of driver discovery that overcomes the limitations of individual methods.

205 This provides opportunities to overcome the limitations of introducing modifying nucleotides, often

206 We discuss limitations of our approach when examining uncharacteriz

207 The main limitations of our study are related to insecurity in th

208 The main limitations of our study are the limited availability of

209 nt research tools and models, as well as the limitations of OXPHOS as drug targets.

210 ct meaningful information, and also describe limitations of pairwise contacts alone to predict absolu

211 and multivariate analysis, overcomes current limitations of plasmonic detection systems.

212 al imaging of brain activity to surmount the limitations of present methodologies.

213 Here, we review the findings and limitations of recent efforts to identify relatively "au

214 Investigators acknowledge the limitations of rodent or non-human primate stroke models

215 mechanistic insights delineate the scope and limitations of S1-chaperoned unfolding of structured RNA

216 We also identify the limitations of soil macroecological studies to explore g

217 anticoagulant with potential to overcome the limitations of standard of care in children with venous

218 We consider the benefits and limitations of strategies developed thus far and provide

219 neration technologies to address the current limitations of systems-based studies of human malaria ar

220 an in-depth investigation of the promise and limitations of the available colocalization analysis app

221 rogress has also been made in addressing the limitations of the avoidance strategy and further refini

222 The strengths and limitations of the consensus predictions were discussed

223 In order to overcome the limitations of the mutant DISC1 model and understand the

224 d with electronic messaging may overcome the limitations of the prior interventions.

225 Limitations of the study include that it was not possibl

226 Limitations of the study included lack of individual-lev

227 Limitations of the study included limited geographic gen

228 Limitations of the study may include potential measureme

229 on, the article discusses the advantages and limitations of the three suggested paths for receiving s

230 We highlight key advantages and limitations of the tool and compare it to other peptide

231 Limitations of these models are discussed, as are future

232 nt developments to demonstrate the scope and limitations of this interesting and versatile functional

233 Within the limitations of this interim analysis, there was no signi

234 The main limitations of this study are that most analyses were pe

235 Key limitations of this study include fair study quality and

236 The main limitations of this study include potential bias from pl

237 Limitations of this study include potential missing data

238 Limitations of this study include that it does not consi

239 Limitations of this study included the limited power and

240 Within the limitations of this study, data suggests GTR is a good o

241 The main limitations of this systematic review lie in the restric

242 This challenge is exacerbated by limitations of traditional cell culture techniques, whic

243 We discuss the limitations of using quantitative measures of alcohol us

244 Strengths and limitations of various analytic test systems are conside

245 Understanding the power and limitations of various read assembly programs in practic

246 is unexpected transition, the advantages and limitations of virtual visits, and potential opportuniti

247 pical regions, our study demonstrates that P limitation often occurs in other regions.

248 ion field experiments reveal a significant P limitation on aboveground plant production.

249 on modeling identified CO(2) as the dominant limitation on J(CO2) on the clay soil.

250 ing spatial pattern of temperature and water limitations on EOP.

251 This poses limitations on our understanding of PM health effects.

252 Although there are important limitations on the validity of drawing causal conclusion

253 Both techniques have limitations, particularly APT, because of insufficient u

254 e our original method was promising, several limitations persisted, including access to more function

255 anistic representation of water and nutrient limitation, plant compositional shifts and tree mortalit

256 dependences can be exploited to address the limitations posed by the spatiotemporal sparseness of th

257 A critical limitation preventing the development of curative strate

258 i NMR measurements indicate that the kinetic limitation reflects limited Li transport at x > 0.86.

259 glycoproteomic undertakings, many technical limitations remain unsolved.

260 Importantly, nutrient limitation shifted cavitation resistance in a species-sp

261 sence of formal primary care diagnoses was a limitation since ascertaining depression and ADHD from p

262 However, the study itself has several limitations; some include limited sample size and variou

263 though this technology is promising, several limitations still exist; most notably, improper structur

264 uction of electrophilic byproducts, a severe limitation that has plagued the physiological applicatio

265 The main limitation that prevents the implementation of adequate

266 o address these problems, but each possesses limitations that constrain widespread use.

267 flows to mass spectrometers have significant limitations that force nonoptimal modifications to upstr

268 quantification by 1H-MRS has some potential limitations that warrant a thorough experimental examina

269 of photosynthesis, the extent of source/sink limitation, the impact of environment, and the extent of

270 Background Despite known limitations, the decision to operate on abdominal aortic

271 of tailoring nano-DDS to address bacteriocin limitations, the successes and failures of this technolo

272 We review a potential solution to these limitations: the use of new "precision" fMRI approaches

273 otheses of plant responses to eCO(2) under P limitation, thereby improving projections of future glob

274 lations, due to methodological and technical limitations, they have been unable to directly test the

275 ease (CVD) has become an increasingly common limitation to effective anticancer therapy.

276 The main limitation to expanding quinoa cultivation, however, is

277 One limitation to note is that we were unable to model for c

278 is a key energy sensor, activated by glucose limitation to resolve nutrient supply-demand imbalances,

279 Limitation to root growth results from forces required t

280 One limitation to the evaluation of potential therapies and

281 decay-rate constants switched from reaction limitation to transport limitation as the floodplain len

282 A major limitation to understanding the origin and fate of T cel

283 ultrastructure of these channels, there are limitations to efficiently addressing their presence ove

284 any CCM or degree of pyrenoid leakiness, and limitations to inorganic carbon in the aquatic habitat,

285 assessment of photosynthesis (gas exchange, limitations to partitioning, photochemistry and galactol

286 Limitations to understanding disparities in palliative c

287 Importantly, upon glucose limitation, Vitamin K2-upregulated glycolysis markedly i

288 The main limitation was use of blood pressure measurement on a si

289 outcome measures, results, and acknowledged limitations was extracted by 2 reviewers.

290 To overcome this limitation, we developed a hybrid data-driven approach b

291 To overcome this limitation, we devised cell models in which the AML1-ETO

292 To overcome this limitation, we have developed a methodology for live ima

293 To address this limitation, we leverage an in vitro ribosome synthesis p

294 The main limitations were that we could not explore the consisten

295 pply, alleviating biophysical photosynthetic limitation when soil water is scarce.

296 ine in the chlorophyll content (non-stomatal limitation), whereas the observed differences between wa

297 of controlled release systems is hindered by limitations, which are discussed in this review.

298 o hybrid devices that overcome many of these limitations, while capitalizing on their respective stre

299 Time consumption and data input limitations will depend on the available resources at th

300 tomatal functions rapidly recover from water limitation (within 24 h of re-watering) in the drought-t