ライフサイエンスコーパス: line

1 previous studies that employed the same cell line.

2 ples allows for annotating large datasets on-line.

3 ient Oli-neu oligodendroglial precursor cell line.

4 the enzalutamide-resistant (Enz-R) VCaP cell line.

5 the thermosensitive CCT-mutant CHO-MT58 cell line.

6 anges with limited overlap between each cell line.

7 hypoxia-induced EGFR TKI resistance in each line.

8 omic analysis of a kidney-derived HLRCC cell line.

9 nse was inconsistent between three ALT+ cell lines.

10 cytotoxicity against a panel of cancer cell lines.

11 a resistance in NRF2-overexpressing HCC cell lines.

12 t observed in radioresistant male NSCLC cell lines.

13 s of differentially methylated isogenic cell lines.

14 lthy control (HC) iPSC lines and 15 SCZ iPSC lines.

15 on and design of biological machine assembly lines.

16 erimentally in 11 patient-derived tumor cell lines.

17 enhances replication in numerous human cell lines.

18 ) were recovered from the analyzed R0 and R1 lines.

19 istance to NDV in inbred Fayoumi and Leghorn lines.

20 from different bone types and 3 HSC reporter lines.

21 genic TP53-WT and TP53-null (TP53(-/-)) cell lines.

22 eral Ewing sarcoma and multiple myeloma cell lines.

23 ity, and human health in open seas and coast lines.

24 esence of spatially diverging magnetic-field lines.

25 is in a sensitive and resistant pair of cell lines.

26 antly no cytotoxicity in four mammalian cell lines.

27 inhibit proliferation of Myc-dependent cell lines.

28 heir activity against five human cancer cell lines.

29 Golabi-Behmel syndrome preadipocyte knockout lines.

30 N cells, while having little effect in MYCNA lines.

31 biquitination levels are reduced in amiR-bpm lines.

32 the first documented cloned Atlantic salmon lines.

33 NF-kappaB, leading to the down-regulation of LINE-1 promoter activity.

34 Despite having 10% less lignin, CCR2(-/*) line 12 grows normally.

35 , and one kind of EpCAM negative cancer cell line (293T kidney cancer).

36 crown rot in University of Florida breeding line #394-1-27-12 (C. moschata) is conferred by three in

37 h as uplift along elevated viaducts of Metro lines 4 and B, as well as differential displacements in

38 rbored genes were specifically identified in line 6(3) and 7(2), respectively.

39 Tau enriched in the synapse of line 66 mice, therefore, appears to be in an oligomeric

40 last NHDF cell lines, and on neoplastic cell lines: acute monocytic leukemia THP-1 and lung adenocarc

41 VvCEB1(opt) -overexpressing lines also showed increased salinity tolerance due to re

42 Comparison of cell line and human patient data suggests that the relative a

43 utants to WT FH levels on a human HAP-1 cell line and on sheep erythrocytes.

44 cells) from the human HUDEP2 erythroid cell line and primary human erythroid cultures.

45 m formalin-fixed tumors, a POLE mutated cell line and standard DNA by WES and five different panels.

46 ents, those living below the federal poverty line and with high household densities had higher crude

47 oping cINs from 15 healthy control (HC) iPSC lines and 15 SCZ iPSC lines.

48 In human breast cancer cell lines and 4T1 mouse mammary tumor cells, PD-L1 expressio

49 Cell lines and acini cultures were incubated with IL22 and ph

50 Herein, we combined reporter cell lines and activity-based protein profiling (ABPP) chemic

51 py in a subset of HER2(+) breast cancer cell lines and allow cancer cells to proliferate in the prese

52 increased PD-L1 expression in the tumor cell lines and caused up to a 12-fold increase in tracer bind

53 With new developments in transgenic lines and human-rodent chimeras, we anticipate that in c

54 fferent active site geometries in three cell lines and peripheral blood mononuclear cells.

55 n several mutant and FLT3-resistant AML cell lines and primary blasts from AML patients, while showin

56 at reduce water depth, stabilizing grounding lines and slowing or reversing glacial retreat.

57 oundary marks and more conserved across cell lines and tissues.

58 lidated with DNA from two breast cancer cell-lines and two patient tumour tissue samples through a qP

59 s the emergence of authentic human beta-cell lines, and advances in genome-editing technologies coupl

60 vitro, with low-passage patient-derived cell lines, and in vivo, using orthotopic models of glioblast

61 Balb/3T3, human dermal fibroblast NHDF cell lines, and on neoplastic cell lines: acute monocytic leu

62 we addressed using cancer patient data, cell lines, and orthotopic mouse models.

63 of differentiation efficiency of individual lines, and utilise heterogeneity in the genetic backgrou

64 stant tuberculosis (TB) given standard first-line anti-TB treatment indicated an increased risk of mu

65 the intrapulmonary pharmacokinetics of first-line anti-tuberculosis drugs.

66 signaling and will respond to potent second-line antiandrogen therapies, including bicalutamide (CAS

67 riophage detection and exposure to the first-line antibiotic azithromycin, detected in stool samples

68 isolates multi-drug resistant (MDR) to first-line antibiotics and 60% were extensively drug-resistant

69 tiveness of beta-lactams, which remain first-line antibiotics for many infections, is an important pa

70 ely drug-resistant (XDR), resistant to first-line antibiotics, fluoroquinolones and third generation

71 uptake inhibitors (SSRIs) constitute a first-line antidepressant intervention, though the precise cog

72 lectrophoresis (PFGE) was applied as a first-line approach, followed by a more refined whole genome s

73 scribe how OOPS can be applied in human cell lines, Arabidopsis thaliana, Schizosaccharomyces pombe a

74 r semi-manual methods, characterization of z-line architecture using the metrics discussed and implem

75 show that transmembrane actin nuclear (TAN) lines are induced by stretch stimulation and nuclear env

76 hPSC) platform, in which 30 isogenic disease lines are pooled in a single dish and differentiated int

77 However, some PDAC cell lines are resistant to VSV.

78 These lines are standardized and can be reproduced over genera

79 tures, including both roads and transmission lines, are substantial sources of mortality.

80 Ordered BCP line arrays with half-pitch of 6.4 nm are demonstrated o

81 5 percentage points, and switching to second-line ART by 1 percentage point compared with standard of

82 rm to one of four curve shapes: the straight line, association exponential curve, rise-and-fall to ze

83 PO and NO as well as the iron lines with Se line at 196.026 were demonstrated.

84 n using cystic fibrosis patient-derived iPSC lines before and after correction of the CFTR mutation,

85 on four melanoma and two neuroblastoma cell lines by high performance liquid chromatography (HPLC).

86 These UBC-GFP lines can be a convenient resource for tracking donor ce

87 Lines carrying AG1 + AG2 QTLs showed higher alpha-amylas

88 Patients receiving second-line chemotherapy followed by resection had significantl

89 rse OS and PFS than patients receiving first-line chemotherapy followed by resection.

90 rse the remaining recommendations for second-line chemotherapy, as well as other recommendations rela

91 IMspire150 aimed to evaluate first-line combination treatment with BRAF plus MEK inhibitors

92 Our studies on several meningioma cell lines cultured in hypoxic conditions validated the assoc

93 itical cancer driver genes by analysing cell-line datasets.

94 vivo, SHH interference in colon cancer cell lines decreased primary tumor growth and metastasis.

95 Radiosensitive male NSCLC cell lines demonstrated a dose-dependent induction of linc-SP

96 ments of the respiratory chain in human cell lines depleted of the catalytic complex IV subunit COX1

97 ransferase 1 in two of three fibroblast cell lines derived from affected individuals.

98 Glial cell line-derived neurotrophic factor (GDNF) binds the GFRalp

99 These are then combined with the cell line-derived transcriptomic datasets through elastic net

100 ermline recombination in distinct Cre driver lines designed for nervous system-specific recombination

101 Arabidopsis AtNFS1 and AtFH overexpressor lines displayed decreased susceptibility to infection by

102 3 Early Treatment Diabetic Retinopathy Study lines (doubling of the visual angle) of uncorrected dist

103 eation of the CD22 interactome in the B cell line DT40.

104 community context to truly know their bottom line effects.

105 of murine HCC models and corresponding cell lines establishes the role of driver genes in diverse co

106 Patient-derived cell lines exhibit sensitivity to topoisomerase and PARP inhi

107 SC-beta cells differentiated from four hPSC lines exhibited first- and second-phase dynamic glucose-

108 producible between individual organoids/iPSC lines/experiments).

109 mbinant human corneal limbal epithelial cell line expressing a LC3-GFP fusion protein was challenged

110 gy with the rapid generation of three BCR KI lines expressing native human precursors, instead of com

111 We used CRISPR-Cas9 to engineer human cell lines expressing POLE tumor variants, with and without m

112 e regimens, and portends high rates of first-line failure in sub Saharan Africa.

113 )I-KX1 was assessed in 19 neuroblastoma cell lines, followed by in-depth pharmacologic analysis in a

114 t, peristaltic pumps equipped with perfusion lines for chemical transport, and mirrors for laser beam

115 more, we fingerprinted a large panel of 4143 lines for the 2NS translocation that provided excellent

116 ngle-cell RNA-seq to profile 198 cancer cell lines from 22 cancer types.

117 Spike-protein-reactive T cell lines generated from SARS-CoV-2-naive healthy donors res

118 genotyped an association panel of 508 inbred lines genotyped with a total of ~550,000 SNPs (Illumina

119 receptor 1 (FGFR1) expression in NSCLC cell lines H1975, HCC827, and YLR086, and knockdown of FGFR1

120 9 knockout screening across hundreds of cell lines has identified genes whose disruption leads to fit

121 ed in cancer patients and tumor-derived cell lines have identified a high frequency of alterations in

122 d Protect-seq on the human colon cancer cell line HCT-116 and observed overlap with previously curate

123 ormed from two established human cancer cell lines (HCT116 and CAL27) to single and combination treat

124 p6 (Kernow C-1) and the human hepatoma cell lines HepG2 and HepG2/C3A with different media condition

125 ogenic human ESC-derived microglia-like cell lines (hMGLs) harboring AD variants in CD33, INPP5D, SOR

126 We tested "the expensive germ line" hypothesis by generating germline-free zebrafish D

127 Analysis of GAL4 lines identified in an unbiased screen for increased fem

128 Proteomic comparison of ILC and IDC cell lines identified induction of PI3K/Akt and p90-RSK pathw

129 ome-seq data from 32 human dermal fibroblast lines, identifying hundreds of differentially expressed

130 LA716 introgression line (IL) population using a combination of scanning ele

131 suites or with portable units, are the first-line imaging test because they are widely available and

132 f a human bladder epithelial progenitor cell line in a dose-dependent manner, achieving far higher ef

133 generating an average of 6.37 insertions per line in a population of 19 independent R1 regenerant pla

134 this study, we cultured ovarian cancer cell lines in adherent and nonadherent conditions in vitro an

135 indicated its presence in 94.1 and 93.7% of lines in the 2019 IBWSN and SAWSN, respectively.

136 ed that ~94% of recently collected isofemale lines in the Drosophila melanogaster Genetic Reference P

137 Tested against a panel of GBM cell lines in vitro, paclitaxel was found to be effective at

138 haracterized using four prostate cancer cell lines, including PC-3, VCaP, DU-145, and LNCaP, obtainin

139 NA events from thousands of samples and cell lines, including: (i) more than 2000 experimentally supp

140 ent labeled exosomes derived from three cell lines injected systemically into C57BL/6 mice revealed t

141 be accessed via four interfaces: the command-line interface, the DSSR plugin for PyMOL, the web appli

142 ng (RNA-seq) analysis of IRAK4 knockout cell lines (IRAK4 KOs) showed that the IRAK pathway induced c

143 Thus, the new mouse line is an ideal tool to study cytotoxic T lymphocyte bi

144 response, which could explain why the 20rDNA line is hyper-resistant to both bacterial and nematode i

145 ignaling in ARR1 gain-of-function transgenic lines is associated with increased rates of protein synt

146 nal repressor binding site in a CAO knockout line it was possible to continuously alter chlorophyll b

147 red cell transfusion and discuss using first-line IV iron monotherapy to treat anemic patients with c

148 ients as well as the blast crisis phase cell lines, Kcl-22 and K562, formed few or no TNTs.

149 logy is systems able to achieve the assembly-line like production of molecules.

150 dback pathways to the electrosensory lateral line lobe (ELL).

151 actions (i.e., combinations of lead service lines [LSL] and corrosion control treatment [CCT] scenar

152 nfection of the choroid plexus and ependymal lining, marked meningitis, and 100% mortality within 2 w

153 st three kinds of EpCAM positive cancer cell lines (MCF-7 breast cancer, SW480 colon cancer, and PC3

154 d cardiac CT or CT angiography are the first-line modalities for clinically suspected endocarditis gi

155 A Broken line model was used to identify the periods of the learn

156 BCR in the endoplasmic reticulum of MCD cell line models and promotes the turnover of immature glycof

157 tihistamines or INCS may be offered as first-line monotherapy for NAR.

158 ivity from the multiple spectral dimensions, line-narrowing, isolation of spectral features where qua

159 Near-isogenic lines (NILs) can be used to characterize, dissect and va

160 The main line of cellular defense against these electrophilic mol

161 practical, and analytical challenges to this line of research and used a preregistered meta-analysis

162 Patients had completed at least one previous line of treatment for advanced breast cancer or relapsed

163 of 0-2, and had received up to two previous lines of chemotherapy for metastatic disease.

164 , is a key periodontal pathogen, and several lines of evidence link the presence of this bacterium in

165 rofiling approaches, we report here multiple lines of evidence suggesting that a major mental illness

166 Combining multiple lines of evidence, including radiocarbon dating, body si

167 s) of the viral life cycle, based on several lines of evidence.

168 Recovery of vision to within 2 lines of pre-endophthalmitis baseline was achieved in 53

169 r refractory DLBCL who received at least two lines of previous chemoimmunotherapy.

170 metabolism support this claim as do multiple lines of research that demonstrate chemical inhibition o

171 ify some of the gaps that could drive future lines of research, hopefully stimulating the growth of t

172 ists that had an important role in the front lines of the battle.

173 Non-line-of-sight (NLOS) imaging is a rapidly growing field

174 Also, the Ornithodoros moubata cell line OME/CTVM22 had the modal chromosome number 33 inste

175 fect of the presence and absence of the germ line on somatic repair under benign and stressful condit

176 With the use of a transgenic mouse line, optical clearing, and imaging techniques, combined

177 ophago-enteric leak from anastomosis, staple line or localized conduit necrosis (9%), and acute delir

178 The event rate for 2-line or more VA gain was 0.49 events/eye-year (95% confi

179 em from matched GE profiles of the same cell line or tissue measured on different platforms.

180 ary intestinal intraepithelial CD8(+) T-cell lines, or CD8(+) T cells directly isolated from intestin

181 istent with the possibility that the 3.5-keV line originates from dark matter decay.

182 eal cellular mechanisms associated with cell line phenotypes and guide process optimization, comprehe

183 structure-function relationships of assembly line PKSs.

184 eometric objects in state space (e.g points, lines, planes), but rather the stability of state trajec

185 Along this line, premenopausal women seem to be generally protected

186 it revealed that cell fitness in cancer cell lines, primary cancer cells, and fibroblasts under unhin

187 itecture for the zebrafish posterior lateral line primordium, an experimentally tractable model of co

188 Here we present SequelTools, a command-line program containing three tools: Quality Control, Re

189 ex quantification of labeled K562 human cell line protein digests via single-shot nanoLC-MS/MS analys

190 5, HeLa, HCT 116, and MCF7 human cancer cell lines provide insights into the impact of structural fea

191 Additionally, we developed a command line Python tool, mirtop, to create and manage the mirGF

192 This was duplicated in a cell line (RBL-MRGPRX2).

193 he transpirational differences between these lines reflected the permeances of their isolated cuticle

194 lure of integrase inhibitor-containing first-line regimens, and portends high rates of first-line fai

195 iating age-appropriate WHO-recommended first-line regimens.

196 EP2 receptor activation in a microglial cell line, reinforcing the use of EP2 antagonists as anti-inf

197 CRISPR knockout of IL37 in lung cancer cell lines repolarized TAMs, resulting in recovered cytolytic

198 AC-sequencing analyses of tumor-derived cell lines revealed downregulation of TGFbeta signaling and u

199 o measure WUE(plant) in a recombinant inbred line (RIL) population created between the C(4) grasses S

200 se experiments using a deconvolved, confocal line scanning approach to score the distribution of the

201 images are acquired in a single pass using a line-scanning spectral confocal microscope.

202 e same genetic background, and 16 homozygous lines selected as a tetragenic system.

203 trometer, which is composed of a grating and line sensor, cannot capture the spectral behavior from n

204 (ZIF-4), as a highly efficient media for on-line separation of phenolic acids and flavonoids, which

205 inuously administered ibrutinib in the first-line setting significantly prolonged progression-free su

206 atezolizumab plus chemotherapy in the first-line setting.

207 small spectral side band, the broad emission line shape is constant to 100 ns.

208 ctroluminescence (MEL) response with similar line shapes as the MC response has a significantly large

209 Planar Goubau lines show promise as high frequency, low-loss waveguide

210 About, one third of the BC(1):F(3) lines showed FHB resistance similar to their M4 parents.

211 h feature sizes as small as 180 nm and 1 mum line spacing was achieved, resulting in the highest reso

212 molar range among various tested cancer cell lines such as A2780 (0.23 muM), PC3 (0.48 muM), and SKOV

213 erization in ARMC9 and TOGARAM1 patient cell lines suggest a role for this new JBTS-associated protei

214 , we created a controllable transgenic mouse line that sustains cortical MET signaling.

215 5 inhibited proliferation of two cancer cell lines that are resistant to cancer drugs and diminished

216 lengths extend naturally in the field, using lines that contain variant alleles for the key photoperi

217 throughput screening to patient-derived cell-lines that have a close connection to the disease biolog

218 he very long electron beam produced spectral lines that were observed to have frequencies upto 21 GHz

219 are highly specialized ependymal cells that line the bottom and the lateral walls of the third ventr

220 A(HI)/F3(HI)/DLL1(HI) mesenchymal population lines the crypt-villus axis and is the source of the epi

221 lamydia trachomatis targets epithelial cells lining the genital mucosa.

222 In mammalian cell lines, the endosomal sorting complex required for transp

223 volumab + ipilimumab as an option for second-line therapy and third-line therapy is discussed.

224 an option for second-line therapy and third-line therapy is discussed.

225 mprovements in patient outcomes for 26 first line therapy trials).

226 al antibiotic delivery was a universal first-line therapy.

227 mechanism of resistance and to guide second-line therapy.

228 cluding our dual fluorescence CRISPRi/a cell lines, this system can facilitate functional dissection

229 outlet channels are typically conducted off-line through microscopic image analysis, or by first col

230 tion of transduction in human and mouse cell lines through type I and type III IFNs.

231 t and label nanoparticles on top of the test line (TL).

232 deletions in an apicoplast metabolic bypass line to determine which genes involved in apicoplast car

233 Using a novel transgenic mouse line to model the impact of human APP (hAPP)/Abeta accum

234 Here, we employed Gdf5-LacZ reporter mouse lines to assess the spatiotemporal activity of Gdf5 regu

235 re, it highlights the potential of fish cell lines to be utilized in integrated testing strategies.

236 is thaliana ecotypes, mutants and transgenic lines to determine how control of VRN2 stability contrib

237 differential susceptibility of the two cell lines to HCoV-OC43 infection, we found that ArfGAP with

238 the genetic diversity of multiple human cell lines to highlight viral determinants that could contrib

239 uggesting that the response of AIS grounding lines to Northern Hemisphere sea-level forcing is more c

240 use of psychological interventions as first-line treatment for depression in low-income and middle-i

241 hemotherapeutic drug, which is used as first-line treatment for some types of colorectal carcinoma, c

242 dotin combined with pembrolizumab as a first-line treatment in February 2020 for cisplatin-ineligible

243 had received Hodgkin lymphoma-directed first-line treatment in randomized GHSG trial protocols was go

244 inib with best supportive care in the second-line treatment of advanced hepatocellular carcinoma over

245 Given the current lack of third-line treatment options, this approach warrants considera

246 rference in colon, pancreatic, and lung cell lines triggered cell death through PTCH proapoptotic sig

247 Analysis of reporter mouse lines TRPV1(PLAP-nlacZ) and TRPV1-Cre:tdTomato combined

248 Pyrazinamide is a sterilizing first-line tuberculosis drug.

249 einhardtii, on average, 10 kinesin-2 motors "line up" in a tight assembly on the trains [3], provokin

250 een shown that patients with HFpEF develop B-lines upon submaximal exercise stress echocardiography;

251 V40)-transformed human fibroblast model cell line used in this study.

252 ausative mutations were identified for three lines using deep sequencing-based bulked segregant analy

253 In this study, we leverage new mouse lines, viral tools, and molecular markers to better defi

254 nograft models and four human and mouse cell lines we examined in vitro cisplatin/JH-RE-06 treatment

255 Along this line, we have developed organic CO prodrugs that allow f

256 ls and an established human endothelial cell line, we investigated the role of AMP-activated protein

257 Using an MrgprC11(CreERT2) transgenic mouse line, we labeled a small subset of itch-sensing neurons

258 Using a Grp-Cre knock-in mouse line, we show that the upper epidermis of the skin is ex

259 these genes are required using different Cre lines, we show that Fgf8 and Fgf17 are required in the p

260 evoid of active processing, of the same cell line were used as references.

261 These lines were evaluated for SD measured by germination at 7

262 Macaque TSC lines were generated by isolating first and second trime

263 Murine HCC cell lines were generated from each tumor model, characterize

264 stem cells (iPSC)-derived neuronal stem cell lines were generated from individuals with MDD.

265 ancreatic tissues, PDA tissue array and cell lines were used to determine the levels of MPC-1 and KDM

266 blue perovskite LEDs, the emission spectrum line width is broadened to over 25 nm by the coexistence

267 ickly adopted this external strategy and, in line with a metacognitive account, children across ages

268 ration after incubation of the RPMI8226 cell line with an increasing activity (0.185-3.7 kBq/mL) of (

269 sion activation and entry properties more in line with betacoronaviruses in lineages A and C, and be

270 ding strategies in hippocampal subfields, in line with computational theories.SIGNIFICANCE STATEMENT

271 These observations were in line with downregulation of PTEN and increase in beta ce

272 In line with earlier work, we found considerable variation

273 12 or 24 weeks with or without ribavirin, in line with existing guidelines.

274 Here we utilise a transgenic line with fluorescent oenocytes to purify these cells fo

275 Similar results with ECG and EGC, but not in line with FQ kinetics, highlighted possible interference

276 In line with its preclinical data, PET imaging resulted in

277 In line with our hypothesis, we provide novel evidence that

278 In line with predictions of this Sync model, midfrontal the

279 idiopathic Parkinson's disease, which is in line with previous findings in murine models.

280 starch and malate turnover are discussed in line with the contrasting roles for these metabolites wi

281 This change is well in line with the threshold voltage of the SCGT, which has b

282 n the formation of carboxyl intermediate, in line with their higher activities and selectivity.

283 In line with theoretical accounts, people's decisions to mo

284 In line with these anatomic observations, animals and human

285 velopment of next-generation TE materials in line with these thermodynamic routes is given.

286 In line with this and with upregulation of PLIN2 protein, G

287 In line with this, inhibition of GSH reductase (GR), the en

288 In line with this, we identified an altered perinatal and/o

289 We have a mouse line with Tropomyosin receptor kinase B (TrkB) receptor

290 Complementation of the At2OGO-KO lines with a barley (cv. Conlon) orthologue, Hv2OGO, res

291 receptor 1 (TfR1) in established human cell lines with a designer disulfide FRET probe.

292 We apply the tfLDA to two cell lines with a rich collection of TFs and identify combina

293 ularly because a large number of cancer cell lines with characteristic mesenchymal features show simu

294 t only predict drug responses in cancer cell lines with high accuracy but also identify features and

295 IEC lines with low endogenous abundance of GSDMD were resist

296 i(3) C(2) T(x) MXene microstrip transmission lines with low-energy attenuation and patch antennas wit

297 cular bands of PO and NO as well as the iron lines with Se line at 196.026 were demonstrated.

298 ynthesis and RRM2 levels was rescued in cell lines with the CRISPR/Cas9-mediated knockout of 4E-BP1.

299 en and closed states reveal a dynamic tunnel lining, with implications for gating or substrate transl

300 porated to triacylglycerol in the transgenic lines without significant changes in their levels in the