1 ovo mutation detection, linkage analysis and
lineage tracing.
2 ney with in situ expression studies and cell
lineage tracing.
3 t can be addressed using single cell dynamic
lineage tracing.
4 he dorsal aspect of the prostatic urethra by
lineage tracing.
5 precision of conventional Cre-loxP-mediated
lineage tracing.
6 he Cell Stem Cell tenth anniversary theme of
lineage tracing.
7 single-cell readouts now enables large-scale
lineage tracing.
8 ese growth regulators as markers for genetic
lineage tracing.
9 essential for many pooled screens and clonal
lineage tracing.
10 and identify cell type-specific markers for
lineage tracing.
11 Lineage tracing (
a method used to track each cell though
12 glandular fission, and more rapid stem cell
lineage tracing,
a process that can be suppressed by exo
13 , histology, and RNAscope in an SMC-specific
lineage-tracing Ahr knockout mouse model of atherosclero
14 Lineage tracing aims to identify all progeny arising fro
15 Lineage tracing aims to identify the progeny of a define
16 Lineage tracing analysis revealed the conversion of beta
17 Lineage tracing analysis with dual-fluorescent reporter
18 By
lineage tracing analysis, we also found that collagen-ex
19 In addition,
lineage-tracing analysis indicated that all mTECs have a
20 Notably,
lineage-tracing analysis revealed Swi/Snf-deficient beta
21 Lineage-tracing analysis revealed that descendants of Sf
22 use next generation sequencing for antibody
lineage tracing and B cell fate mapping.
23 y of skeletal muscle-resident macrophages by
lineage tracing and bone marrow transplant experiments.
24 h the origin(s) of infarct fibroblasts using
lineage tracing and bone marrow transplants and a robust
25 Lineage tracing and busulfan challenge show that these a
26 Using
lineage tracing and DNA pulse-chase analyses, we identif
27 Lineage tracing and fate mapping, overlapping yet distin
28 Using
lineage tracing and flow cytometry, approximately 40% of
29 Lineage tracing and functional analyses demonstrate that
30 We combined
lineage tracing and functional analyses in a sequential
31 Here we show through
lineage tracing and genetic ablation that BMI1(+) CSCs m
32 Using
lineage tracing and genetic label-retention assays, we s
33 Lineage tracing and IgH repertoire analyses revealed min
34 Lineage tracing and immunohistochemical analyses reveale
35 Data from in vivo imaging, cell-
lineage tracing and knockout studies in mice, as well as
36 Using
lineage tracing and label retention experiments, we show
37 By timing the interval between LGR5(+)
lineage tracing and lethal injury, we show that ISC rege
38 We use two complementary approaches,
lineage tracing and live fluorescent microscopy, which b
39 including genome-wide screens, gene therapy,
lineage tracing and molecular recording.
40 Here we use cell
lineage tracing and multiple in vivo approaches to study
41 l RNA sequencing in combination with in vivo
lineage tracing and organoid models to finely map the tr
42 Lineage tracing and quantitative clonal analysis reveal
43 pithelial lineage relationships, we combined
lineage tracing and recovery from transient in vivo mTEC
44 A method for combined
lineage tracing and scRNA-seq reveals the interplay betw
45 Combining
lineage tracing and scRNA-seq, we show that Lgr5 marks E
46 By combining pulse-chase
lineage tracing and single-cell RNA sequencing, we obser
47 eterogeneity of these cells as determined by
lineage tracing and single-cell sequencing in developmen
48 on to known ectodermal contributions, we use
lineage tracing and time-lapse imaging in zebrafish to i
49 Using in vivo
lineage tracing and triple negative breast cancer (TNBC)
50 Lineage-tracing and activity-tracing studies in the mous
51 Here, using
lineage-tracing and molecular genetic studies in the roo
52 In zebrafish, previous
lineage-tracing and mutant analyses suggested that SHF v
53 Using genetic
lineage-tracing and neural crest-deficient mutants in ze
54 Using genetic
lineage-tracing and scanning-block face electron microsc
55 irculating memory (TCIRCM), and TRM pools by
lineage-tracing and single-cell transcriptome analysis.
56 origin of melanoma, we combined single-cell
lineage-tracing and transcriptomics approaches with time
57 Using explant studies,
lineage tracing,
and clonal analysis, we demonstrate tha
58 ation with molecular identification, genetic-
lineage tracing,
and mutant analyses.
59 We employ genetics, cell
lineage tracing,
and single molecule imaging to show tha
60 Recent studies have applied transgenics,
lineage-tracing,
and transcriptomics to help decipher th
61 s of this study were to evaluate, by using a
lineage tracing approach, the contribution of peribiliar
62 is healing, Gli1 expression was examined via
lineage tracing approaches and the effect of Smo deletio
63 oadly review the origins of fate mapping and
lineage tracing approaches.
64 Sophisticated
lineage-tracing approaches for analyzing embryogenesis h
65 Here we show, using unbiased quantitative
lineage-tracing approaches, biophysical modelling and in
66 Using genetic and
lineage-tracing approaches, we describe novel dorsal and
67 me-lapse imaging, protocol optimization, and
lineage-tracing approaches.
68 d by analysing clonal data from in vivo cell
lineage-tracing assays.
69 Independent
lineage tracing based on Stmn1 and Ki67 expression confi
70 Lineage tracing by using Cdh5cre(ERt2)/Rosa-YFP reporter
71 Here, we describe the CRISPR array repair
lineage tracing (
CARLIN) mouse line and corresponding an
72 e wide-ranging applications, such as in deep
lineage tracing,
cellular barcoding, molecular recording
73 Using genetic
lineage tracing,
clonal analysis, multiplexed in situ hy
74 Using
lineage tracing combined with whole brain clearing, we p
75 We used
lineage tracing,
conditional deletion, mosaic analysis a
76 Lineage tracing confirmed that germ cells die as clones
77 Lineage tracing confirmed that LDB1-depleted, insulin-ne
78 Genetic
lineage tracing confirms the presence of the Tbx6(+) NMP
79 escent, self-renew, and, as shown by genetic
lineage tracing,
contribute to all 3 pancreatic lineages
80 an experimental model system using in vitro
lineage tracing coupled with exome, transcriptome and in
81 n the intestinal epithelium, and a year-long
lineage-tracing course revealed that genetic blockade of
82 y, we generate the most complex experimental
lineage tracing dataset to date, 34,557 human cells cont
83 In the latter, genetic
lineage tracing demonstrated the epicardial origin of fi
84 igorous control of Cre-loxP recombination in
lineage tracing,
effectively circumventing potential unc
85 should broadly enable large-scale mammalian
lineage tracing efforts.
86 Lineage tracing established that Hey-deficient ECs are u
87 the preparation and validation of cells for
lineage tracing,
establishment of grafts and label induc
88 rall data size, and accomplish high-fidelity
lineage tracing even for increased imaging time interval
89 y regulator, we disclose molecular proof and
lineage tracing evidence showing the distinct MSCs contr
90 This study provides direct
lineage tracing evidence that a cardiomyoblast populatio
91 Recently, genetic
lineage tracing experiments have revealed chondrocyte pr
92 Lineage tracing experiments in Foxc1 mutant mouse cerebe
93 lytic approach, we show that data from eight
lineage tracing experiments is consistent with tissue ma
94 Lineage tracing experiments of the gastric corpus in mic
95 ID deletion, single-cell RNA sequencing, and
lineage tracing experiments point to selection of relati
96 Lineage tracing experiments revealed accumulation of ex-
97 Lineage tracing experiments show that Bglap-expressing c
98 Lineage tracing experiments show that GATA/CD24hi cells
99 Lineage tracing experiments show that MECs contribute to
100 We performed
lineage tracing experiments to determine the fates of pe
101 ow transplantation and Cre recombinase-based
lineage tracing experiments, we rule out cell fusion eve
102 oit a Prdm1.CreERT2-LacZ reporter allele for
lineage tracing experiments.
103 Using genetic-
lineage-tracing experiments and an in situ labeling appr
104 We performed cell
lineage-tracing experiments and analyzed the microbiomes
105 fferentiation process was validated by using
lineage-tracing experiments based on Sox18Cre(ERt2)/Rosa
106 However,
lineage-tracing experiments demonstrate that cells from
107 Lineage-tracing experiments identified villin-expressing
108 Recent
lineage-tracing experiments in chick and zebrafish embry
109 Here, by
lineage-tracing experiments in fetal or postnatal mice,
110 In vivo
lineage-tracing experiments in molars showed the contrib
111 Lineage-tracing experiments indicated that the majority
112 sed Sox9 and Ngn3 mRNA levels in islets, but
lineage-tracing experiments revealed that neoformed beta
113 Lineage-tracing experiments revealed that PW1(+) cells d
114 Lineage-tracing experiments revealed that the cells that
115 Lineage-tracing experiments showed that CC10(+), but not
116 terior axis, as demonstrated by foundational
lineage-tracing experiments that showed the restricted d
117 troversies, including the failure of initial
lineage-tracing experiments to confirm a major role for
118 However,
lineage-tracing experiments using an inducible Tbx18-Cre
119 Here, by combining
lineage-tracing experiments with a model of severe gland
120 Based on
lineage-tracing experiments, non-hepatocytes did not con
121 Through
lineage-tracing experiments, we show that bLECs arise fr
122 vide the first direct evidence using genetic
lineage tracing for two basic assumptions in Schwann cel
123 we review major discoveries in neural crest
lineage tracing from a historical perspective.
124 reased epidermal proliferation with expanded
lineage tracing from epidermal stem cells positive for L
125 Here we use
lineage-tracing from development, through adult homoeost
126 Parp1 knockout in preadipocytes in a mouse
lineage-tracing genetic model increases adipogenesis, le
127 Retrospective
lineage tracing harnesses naturally occurring mutations
128 In the lung,
lineage tracing has been used to identify distinct epith
129 Single-cell RNA sequencing (scRNA-seq) and
lineage tracing identified a TCF-1(+)Ly108(+)PD-1(+) CD8
130 Lineage tracing identified intrinsic recruitment of Scx-
131 For example, photoconversion cell-
lineage tracing identified migratory and proliferative c
132 Here, using AXIN2
lineage tracing in BAC-transgenic mice, we confirm the r
133 Using
lineage tracing in Lgr5-EGFP-CreERT2/Rosa26-Tomato and L
134 Genetic
lineage tracing in mice indicates that gastrin expressio
135 By
lineage tracing in mice, we have shown recently that clu
136 Furthermore,
lineage tracing in postnatal and adult glands provides t
137 ncoding and optimal transport principles for
lineage tracing in settings where existing experimental
138 ion of stem cell-derived clones using sparse
lineage tracing in the regenerating mouse olfactory epit
139 Here, I have used single-cell
lineage tracing in the whole mouse uterus to demonstrate
140 here, using gene expression and fate mapping/
lineage tracing in zebrafish, that pineal progenitors or
141 Quantitative
lineage-tracing in vivo revealed that conditional deleti
142 Genetic
lineage tracing indicated that stromal cells blocking th
143 s of pancreatic ductal adenocarcinoma, where
lineage tracing indicates that Cytokeratin-Synaptophysin
144 Lineage tracing involves the identification of all ances
145 Lineage tracing is a powerful tool that can be used to u
146 , IPMNs and PDAC expressed the duct-specific
lineage tracing marker yellow fluorescent protein.
147 Here we present CRISPR-UMI, a single-cell
lineage-tracing methodology for pooled screening to acco
148 In this study, we used
lineage tracing methods to determine the lineage relatio
149 When compared to existing retrospective
lineage tracing methods, RETrace achieved higher accurac
150 Parallel advances in sequencing-based
lineage-tracing methods now facilitate the mapping of cl
151 anced in vivo imaging techniques, transgenic
lineage tracing mice, and clinical interventional studie
152 nd rabies virus approaches in transgenic SVZ-
lineage-tracing mice, SVZ-derived neurons synaptically i
153 We used a genetic
lineage tracing model to investigate whether endothelial
154 dressed major concerns with the Tri-PyMT EMT
lineage tracing model, which provides us with a powerful
155 Here, we demonstrate that a murine EC
lineage-tracing model (Cdh5-Cre(ERT2):ZSGreen(l/s/l) mic
156 In this study, we use genetic
lineage-tracing models and adoptive transfer protocols t
157 Using murine
lineage-tracing models and gene expression profiling, we
158 Herein we use multicolor
lineage-tracing models to confirm that the mature SMC ca
159 vascular-cell-specific and pericyte-specific
lineage-tracing models to trace the fate of perivascular
160 post-Aire MHCII(lo) subset as identified by
lineage-tracing models.
161 In this study, we combined immunocompetent
lineage tracing mouse models of GBM with high-resolution
162 bulk RNA sequencing, and an innovative dual
lineage tracing mouse to understand the mechanism by whi
163 We generated a new Abcg2-driven
lineage-tracing mouse model with efficient labeling of S
164 Using
lineage tracing,
murine models of heart calcification an
165 utively express either Cre-GFP or Tomato for
lineage tracing of a mutant and a reference group of cel
166 We used single-cell sequencing and genetic
lineage tracing of c-kit(+) cells to determine whether v
167 Here, we performed in vivo
lineage tracing of cells with an expression history of I
168 Lineage tracing of cranial neural crest cells revealed t
169 line (Kim1-GCE) in order to perform genetic
lineage tracing of dedifferentiated cells while measurin
170 In toto live imaging and
lineage tracing of drl-based reporters captures the dyna
171 Recently,
lineage tracing of endothelial cells in mouse models all
172 Here we show that
lineage tracing of Gdf5-expressing joint interzone cells
173 the risk for allergy, temporally controlled
lineage tracing of group 2 innate lymphoid cells (ILC2s)
174 of FoxP3 in a fraction of apoB(+) T(regs) in
lineage tracing of hyperlipidemic Apoe(-/-) mice.
175 Lineage tracing of Luminal-C cells indicated that Dist-L
176 Tamoxifen-inducible genetic
lineage tracing of mature adipocytes and single-cell RNA
177 Lineage tracing of peri-injury Axin2(+) hepatocytes show
178 Here, we performed clonal multicolor
lineage tracing of skeletal muscle stem cells (MuSCs) to
179 ith specific expression patterns and perform
lineage tracing of subpopulations of escort cells and fo
180 ed sustained clonogenic growth in vitro, and
lineage-tracing of Prox1(+) cells revealed long-lived cl
181 METHODS AND Using genetic
lineage tracing or bone marrow transplant, we found no e
182 We focus on the most recent developments in
lineage tracing,
permitted by advances in single-cell ge
183 By combining in vivo clonal
lineage tracing,
proliferation kinetics, single-cell tra
184 Recent advances in genetic
lineage tracing provide insight into epithelial lineage
185 Lineage tracing provided formal genetic proof that the u
186 Lineage tracing provides key insights into the fate of i
187 Transgenic
lineage tracing revealed strong clonal competition that
188 Trajectory modeling together with
lineage tracing revealed that airway and alveolar stem c
189 Consistent with these findings, cell
lineage tracing revealed that IH(30) increased the propo
190 Genetic
lineage tracing revealed that pericentral Lgr5(+) hepato
191 In vivo
lineage tracing revealed that the gene transfer of SeV-G
192 Genetic in vivo
lineage tracing revealed that the Krt15 promoter marks a
193 Genetic
lineage tracing revealed that the stemness of a bladder
194 Here, genetic
lineage tracing revealed that, during murine embryonic d
195 Endothelial cell
lineage tracing showed that BNP directly stimulated the
196 ohistochemistry, flow cytometry, and genetic
lineage tracing showed that infiltrating CCR2 cells incl
197 CreERT2 marks both AMFs as well as ALFs, and
lineage tracing shows that ALFs are retained in adult al
198 Genetic
lineage tracing shows that specific diencephalic ependym
199 Quantitative
lineage tracing shows that THRA mutation-containing prog
200 We used genetic
lineage tracing,
single-cell RNA sequencing, and organoi
201 Here, by using live imaging,
lineage tracing,
single-cell transcriptomics and genetic
202 We combined
lineage tracing,
single-cell transcriptomics, and electr
203 these dedifferentiating cells using several
lineage-tracing strains and single-cell mRNA-seq, and we
204 We use multiple models and
lineage tracing strategies to show that this squamous-co
205 Intricate
lineage-tracing strategies and experimental models of re
206 Recently,
lineage-tracing strategies have revealed that Gdf5-linea
207 Using 2 independent
lineage-tracing strategies in murine models, we show tha
208 In contrast to other
lineage-tracing strategies, the method described here as
209 Moreover, using a
lineage tracing strategy, we provide evidence that high
210 Here, we have employed a
lineage-tracing strategy that uses a tamoxifen-dependent
211 Employing a p63(CreERT2)-based
lineage-tracing strategy, we identified a unipotent fate
212 Using a
lineage-tracing strategy, we specifically labeled fetal-
213 nd in vivo Matrigel plug assay together with
lineage tracing studies and single cell RNA-sequencing t
214 Genetic
lineage tracing studies demonstrate that the native endo
215 Lineage tracing studies demonstrated that Ctsk-Cre could
216 Lineage tracing studies demonstrated that the original G
217 ar smooth muscle cells (VSMCs), we performed
lineage tracing studies in mice to further clarify this
218 Lineage tracing studies in mouse suggest that chondrocyt
219 Furthermore, cell
lineage tracing studies revealed that the Axin2(+)-mesen
220 Integrating cell-specific
lineage tracing studies, spatially specific mRNA transcr
221 Here, we used
lineage tracing studies-labelling cells expressing Cx3cr
222 l types can complicate the interpretation of
lineage-tracing studies and has caused controversy in ma
223 However,
lineage-tracing studies have highlighted flaws in the in
224 Recent
lineage-tracing studies have shown that mature hepatocyt
225 In
lineage-tracing studies of mice, we found that Gli1(+) P
226 Lineage-tracing studies revealed that these MAC2+ cells
227 In particular, we revisit recent
lineage-tracing studies that shed light on this issue an
228 cuss how advancing technologies have refined
lineage-tracing studies, and how clonal analysis can be
229 Based on evidence from in vivo genetic
lineage-tracing studies, pericytes have been identified
230 ent studies with single cell transplants and
lineage tracing suggest that adult HSCs are diverse in t
231 opment and validation of a recombinase-based
lineage tracing system for the chicken embryo to further
232 Here we describe a new genetic
lineage tracing system that incorporates the Dre-rox rec
233 By using a newly developed dual-
lineage tracing system, we show that bipotent alveolar c
234 re, using a newly generated Hoxa11-CreER(T2)
lineage-tracing system, we show Hoxa11-lineage marked ce
235 However, recent investigations using cell
lineage tracing techniques have demonstrated that many,
236 d for DNA-based information storage and cell
lineage tracing technologies.
237 Recent studies using genetic
lineage tracing technology have implicated diverse organ
238 nfluential study based on fluorescence-based
lineage tracing technology provided evidence that very f
239 Using
lineage tracing technology, we demonstrate that after ch
240 Here, we have developed a novel dual
lineage-tracing technology, using a combination of two r
241 Using
lineage tracing,
temporal single-cell analyses, and chro
242 including their own, that suggested based on
lineage tracing that mural cells are adipogenic, contras
243 Here we show by genetic
lineage tracing that PROM1(+) cells are derived in part
244 Here, we demonstrate by cell
lineage tracing that the gills of a cartilaginous fish,
245 In a genetic
lineage tracing the WT1(CreERT2+/-)Rosa(tdT+/-) mouse mo
246 reatly enhance biomedical research involving
lineage tracing,
the evaluation of stem cell therapy, an
247 Here we combine clonal analysis, genetic
lineage tracing,
tissue transplantation, and mutant char
248 ostembryonic day 5 (P5) gonads and performed
lineage tracing to analyze primordial follicles and wave
249 EMBLEM extends
lineage tracing to any eukaryotic organism without genet
250 and robust statistical analyses with in vivo
lineage tracing to define a detailed map of the postnata
251 ysis, cell proliferation assays, and genetic
lineage tracing to define the lineage relations and rest
252 Beattie et al. (2017) use elegant MADM-based
lineage tracing to demonstrate cell-intrinsic and global
253 (2017) and Kohler et al. (2017) use in vivo
lineage tracing to demonstrate that these two possibilit
254 CGA), functional approaches, and single-cell
lineage tracing to derive a unified model of cellular st
255 We next employed inducible
lineage tracing to fate map, through Cre recombinase-med
256 lls were present, which we showed by genetic
lineage tracing to have a non-hematopoietic origin.
257 Here, we used random
lineage tracing to localize and quantify clonal expansio
258 Here we use genetic
lineage tracing to mark the Nppa(+) or Hey2(+) cardiomyo
259 ith smooth muscle cell (SMC) and endothelial
lineage tracing to survey all plaque cell types and rigo
260 Here, we use cell
lineage tracing to test the embryonic origin of the phar
261 . report on their employment of a battery of
lineage-tracing tools to address the developmental origi
262 Using genetic
lineage tracing,
transcriptome, and functional studies,
263 Lineage-tracing,
transcriptome, and chromatin analyses s
264 We observed that in the
lineage-tracing transgenic mice Cdh5-CreER(T2)::R26R-EYF
265 firm the fidelity and sensitivity of the EMT
lineage tracing (
Tri-PyMT) model and highlight the diffe
266 of EMT in metastasis, we established an EMT
lineage tracing (
Tri-PyMT) model, in which tumor cells u
267 Genetic
lineage tracing unravels cell fate and plasticity in dev
268 ble Hnf1b:CreER(T2) in the lung, we employed
lineage tracing using an mTmG (G) reporter allele.
269 Lineage tracing using EdU-labeling demonstrates that don
270 Lineage tracing using Fsp1-Cre: R26R-EYFP mice revealed
271 Lineage tracing using global fluorescence labeling techn
272 Lineage tracing using Rosa-td tomato (Col2-Cre-ERT2) mic
273 Lineage tracing was induced in Lrig1-CreERT2/+;R26R-YFP/
274 Lineage tracing was used to rule out repopulation from n
275 Using
lineage tracing we demonstrated that MEndoT-derived cell
276 By combining unbiased and targeted
lineage tracing,
we address the events leading to islet
277 Using single-cell RNA-seq and
lineage tracing,
we analyzed cellular diversity in medul
278 Through inducible
lineage tracing,
we demonstrate that these cells can gen
279 Using additional prospective
lineage tracing,
we demonstrate that while SHF ventricul
280 Through in vivo
lineage tracing,
we demonstrated the power of this appro
281 ene deletion, small molecule inhibition, and
lineage tracing,
we elucidated TGFbeta-dependent and TGF
282 Through
lineage tracing,
we extend these observations to all lon
283 pair models, single-cell transcriptomics and
lineage tracing,
we find that alveolar type-2 epithelial
284 ing single-cell RNA sequencing (RNA-seq) and
lineage tracing,
we found that transforming growth facto
285 Using cell
lineage tracing,
we further demonstrate that trunk neura
286 Using scRNA-seq profiling and genetic
lineage tracing,
we show that RUNX1(+) PLCs are unaffect
287 Using cell
lineage tracing,
we show that skate trunk vertebrae aris
288 Using sonic hedgehog
lineage tracing,
we show that the third and fourth ventr
289 -seq, trajectory analysis, and combinatorial
lineage tracing,
we showed here that the Neurog3(+) cell
290 Using genetic
lineage tracing,
we systematically investigated the role
291 ing a combination of single-cell RNA-seq and
lineage-tracing,
we find that progenitor cells are the p
292 Time-lapse imaging and genetic cell-
lineage tracing were used to identify a source of GDNF-t
293 Using temporal
lineage tracing,
whole-mount confocal imaging, and quant
294 Using single-cell RNA sequencing,
lineage tracing,
whole-organ explant, and live-cell imag
295 We have combined
lineage tracing with antibody cloning from single B cell
296 By combining Cxcr4-CreER-mediated
lineage tracing with Cxcr4 inhibition or conditional Cxc
297 marked by sox10, plp1a, gfap or s100 Rather,
lineage tracing with lipophilic dye or inducible Sox10-C
298 pithelial lineages in adult animals, and via
lineage tracing with stable barcodes, we found that each
299 assay from explanted heart tubes and genetic
lineage tracing with the endocardial specific Nfatc1-Cre
300 Here, we show using Myh11-CreER(T2)
lineage-tracing with inducible SMC and pericyte (SMC-P)