ライフサイエンスコーパス: link

1 all four consensus functional domains to be linked.

2 -site bonding, leading to higher dimensional linking.

3 te more unity through a common knowledge hub linking academia, industry, healthcare providers and hop

4 provide secure low data rate communications links across short distances.

5 he RNA 3' processing factor FY (WDR33), thus linking activities for proximal polyadenylation of the a

6 veal an unanticipated role of HIF2alpha, and link acute and chronic adaptive responses to hypoxia.

7 ctly correlated with levels of protein-cross-linking AGEs.

8 a role in the amyotrophic lateral sclerosis-linked aggregation of SOD1.

9 ments were realized upon replacing the ether-linked amines with carbon-linked morpholines, a modifica

10 erstanding of organismal functioning, as the link among electron transfer, metabolism, energy conserv

11 Functional and lipidomic analyses further link AMPK regulation of ferroptosis to AMPK-mediated pho

12 The X-linked and autosomal genes independently influence mitos

13 channels and demonstrates that large disease-linked and experimentally generated C-terminal truncated

14 in responses to drug and nondrug reward are linked and together form a risk profile for drug use or

15 uripotency progression and morphogenesis are linked and whether intermediate pluripotent states exist

16 we performed enhanced ultraviolet (UV) cross-linking and immunoprecipitation followed by sequencing (

17 Enhanced UV-cross-linking and immunoprecipitation of these RBPs identifies

18 et tau pre-mRNA in cells, via chemical cross-linking and isolation by pull-down target profiling, and

19 LBDs that might be trapped by cysteine cross-links and metal bridges.

20 Our findings link animal and human studies on the neural underpinning

21 ted by the selective cleavage of a tetrazine-linked antibody-drug conjugate by trans-cyclooctenes, af

22 tify a highly conserved regulatory mechanism linking anxiety and alcohol intake that might contribute

23 glycan ligand information is displayed, and links are provided for structural visualization and redi

24 , with various photonics devices and optical links being demonstrated.

25 d organ-restricted autoimmunity, including a link between anti-KHDC3L autoantibodies and premature ov

26 This provides a link between astronomical observations of star formation

27 Our data suggest a causal link between Ca(2+) dysregulation and primary, nonapopto

28 92 CD56-KO cells, demonstrating a functional link between CD56 and signaling in human NK cells.

29 ick in the absence of Mla; providing another link between cell envelope homeostasis and stringent res

30 lis, we identified factors that revealed the link between chromosome translocation and peptidoglycan

31 Our results indicate no clear link between coral age and microbial diversity or richne

32 mage in our mouse model, supporting a causal link between decreased chromatin accessibility and photo

33 s provide support for a possible mechanistic link between early driver mutations in RAS and KIT and t

34 f within-host evolution provide an important link between experimental studies of virus evolution and

35 Our results not only reinforce the existing link between Golgi fragmentation and neurodegeneration b

36 vity and, therefore, strengthen the putative link between grid cells and behaviour along with their c

37 Previous studies have demonstrated a link between indigenous land management and avoided defo

38 omic epidemiology can help to understand the link between individual clusters and wider community spr

39 Dicarbonyl electrophiles represent a link between inflammation and somatic genomic alteration

40 ort to the POLS hypothesis suggests that the link between life history and personality may only emerg

41 However, establishing a firm link between macro-scale brain network organisation and

42 Thus, our work supports a mechanistic link between mitochondrial function and common neurodege

43 We first discuss the link between movement coordination and interval-based ti

44 ring a pathological mechanism underlying the link between muscle aging/senescence and osteoporosis.

45 ate immune cells, potentially explaining the link between mutations and increased cardiovascular risk

46 The homeostatic link between oxidative stress and autophagy plays an imp

47 Our results demonstrate a link between pathological localisation of ANKH mutants w

48 Given the established link between perforin deficiency and primary HLH, we inv

49 Aside from the direct anatomic link between PVN and RAIC, our findings provide evidence

50 ion using video microscopy, we find a strong link between RBC tension and merozoite invasion, and ide

51 Although a link between regular yogurt consumption and mortality ap

52 results provide further evidence of a causal link between sensorimotor beta bursts and movement initi

53 replication stress, uncovering an unexpected link between stress and sister chromatid cohesion loss.

54 Our findings define AP-1 as the key link between T cell activation and chromatin remodeling.

55 Our results provide a chemical link between the Hofmeister series and the cellular proc

56 s, many recent studies have investigated the link between the oral microbiome and these cancers.

57 sis of these variants provided a more formal link between these phenotypes and lincNORS, further stre

58 ancer blocking establish a direct regulatory link between this enhancer and lncRNAs PCAT1, PRNCR1 and

59 FECD pathogenesis and demonstrates a strong link between UVA-induced estrogen metabolism and increas

60 iotic progress, possibly by facilitating the linking between PRDM9-bound hotspots and the nascent chr

61 Our findings reveal new links between avian physiology, ecology, behaviour and l

62 rmines HSC fate, and especially focus on the links between mitochondria, endoplasmic reticulum (ER),

63 icies, especially in countries with stronger links between neighborhood and depression, should focus

64 t development, homeostasis, and disease, but links between specific dietary fats and cell fates are p

65 of the new findings and explore mechanistic links between the cellular and network properties of, an

66 Abundant links between the gut microbiota and human health indica

67 ordered media allows us to formulate precise links between the statistics of environmental challenges

68 ry 1, 1996 to December 31, 2015 using record-linked birth and hospitalisation data from Denmark, Scot

69 Here, we show that multiple linked but recombining loci underlie cryptic color morph

70 ed of repeating saccharides covalently cross-linked by peptide stems.

71 es related to eruptions at arc volcanoes are linked by structures that transect the entire crust.

72 composition of the five CD16a asparagine(N)-linked carbohydrates (glycans) impacts affinity.

73 Biophysical studies on single cells have linked cell mechanics to physiology, functionality and d

74 tary highlights the article by Li et al that links ceramide accumulation in podocytes to cellular dam

75 brillin individually as well as in the cross-linked complex.

76 Ester-linked, crystalline, porous covalent organic frameworks

77 information-seeking behavior (number of web links demanded out of 10 proposed).

78 l from 15 to 60 degrees C using borate cross-linked dextran sieving matrix.

79 yielding a nonhydrolyzable phosphonothiolate-linked diubiquitin and an ubiquitin-alpha-synuclein conj

80 mer pair with unique DNA handles in order to link DNA origami nanostructures bearing complementary st

81 Our study links DNA methylation to disease endpoints via intermedi

82 contrast with previous therapeutics directly linking Dox and TF, cytotoxicity of CDT resulted from nu

83 We propose Sym004 cross-links EGFR physically triggering EGFR endocytosis and in

84 Our data thus link engagement of the CRN to the temporal dynamics of e

85 cific transcriptional regulatory networks by linking enhancers and predicted bound transcription fact

86 We cross-linked EPIC with gene ontology and anatomy ontology term

87 Linking ex vivo gene down-regulation with in vivo neuroi

88 ligand DAF-7 likely acts upstream of IIS and links feeding to odr-10 only in males, due in part to th

89 These findings link fertility to nutritive environment and point to Sax

90 frameworks and cannot be accessible by imine-linked frameworks, amorphous analogues, and 1D conjugate

91 alpha-Linked galactose is a common carbohydrate motif in natur

92 iversity found within humans, our ability to link genes to phenotypes is based upon a handful of mode

93 atory control during hypoxia at altitude, by linking genetic factors with cardiovascular dynamics, as

94 Linking genomic variation to phenotypical traits remains

95 suggested that the two acuities are strongly linked given that they both depend strongly on retinal e

96 ression of both tumor-associated truncated O-linked glycans and their receptor, macrophage galactose-

97 Here, we confirm that the core 2 O-linked glycans mediate this lubricin-galectin-3 interact

98 at in addition to antigenicity, changes in N-linked glycosylation sites can alter other properties of

99 MICAL1 links GRAF1b/2 to Rab8a/b and Rab10, and WDR44 binds Rab

100 Whether this link has any causal aspects to it remains to be explored

101 larly with regards to the use of photo-cross-linking (i.e., light-based) techniques.

102 Here, an inexpensive cellulase-linked immunomagnetic methodology was developed for the

103 We evaluated these antigens by enzyme-linked immunosorbent assay (ELISA) using sera from naive

104 Here, we developed a simple enzyme-linked immunosorbent assay (ELISA)-based assay that uses

105 eurofilament light chain (NfL), using enzyme-linked immunosorbent assay and electrochemiluminescence.

106 n peri-implant crevicular fluid using enzyme-linked immunosorbent assay method and assessed with clin

107 We used an enzyme-linked immunosorbent assay to measure levels of spontane

108 ntibody titer (measured by inhibition enzyme-linked immunosorbent assay) and dengue severity, categor

109 l-time polymerase chain reaction, and enzyme-linked immunosorbent assay.

110 We further demonstrate that cross-linking impairs the cholesterol efflux mediated by apoA-

111 ractions in the rhizosphere are an essential link in soil nitrogen (N) cycling and plant N supply.

112 Glucagon and its partner insulin are dually linked in both their secretion from islet cells and thei

113 we analyzed the pattern of apoprotein cross-linking in isolated human HDL either by synthetic gamma-

114 th its environment, from ecotoxicity and new links in marine food webs to the fate of the plastics in

115 ulmonary resuscitation (CPR) are the first 2 links in the chain of survival for out-of-hospital cardi

116 Linking individual and population scales is fundamental

117 g sets of Chlamydia-MHC class II epitopes to link inductive and effector phases to generate protectiv

118 We believe our ability to link infinite building blocks, such as the ribbons of CO

119 gulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is a lethal disease caused by mut

120 an antifolate stress response in E. coli and links its associated metabolites to a major immunologica

121 Linking levels of influence has been proposed in theory

122 In this work, we aim to link ligand chemical structures to MIEs for androgen rec

123 Analysis of clinical transplantation data linked low circulating levels of GDF15 to an increased i

124 stion is to understand how large-scale cross-linking mass spectrometry (XL-MS) can confirm and extend

125 y purification, live cell imaging, and cross-linking mass spectrometry to build integrative structura

126 ing cryoelectron microscopy (cryo-EM), cross-linking mass spectrometry, and homology modeling.

127 We introduce a new method, Reg-Seq, that links massively parallel reporter assays with mass spect

128 ts reveal the structural determinants of tip-link-mediated inner-ear sensory perception and elucidate

129 Linking microsite consumption of O(2) with a diffusion m

130 Uncovering this link might open novel ways of treatment and prevention t

131 mbinant NUDT3 (Nudix [nucleoside diphosphate linked moiety X]-type hydrolase 3) in vitro.

132 ned and synthesized new functional and cross-linking monomers, which are oxidized at sufficiently low

133 eplacing the ether-linked amines with carbon-linked morpholines, a modification motivated by free ene

134 platforms offer an opportunity to covalently link multi-electron redox responsive POM cores with virt

135 Full-length transcript analysis links multiple alternative splicing events together and

136 l remodeling genes, including S100a10 (p11), linking neuronal plasticity to the antidepressant respon

137 imately 30,000 British members that includes linked nutritional data on purchases.

138 a(13) C and WUE(plant) suggests an intrinsic link of delta(13) C with WUE(i) in this C(4) plant, and

139 al-parametric QTR-FRET technique enables the linking of guanine nucleotide exchange factor-induced Eu

140 and many more plasmid vectors, but also new links of the plasmids to advanced bioinformatic tools.

141 We review recent studies on the mechanisms linking opioids and sleep.

142 nthon-driven approach to fabricate Borromean linked organic polymer.

143 ept of a role for inflammation in PRKN/PINK1-linked Parkinson's disease.

144 te the detection and identification of cross-linked peptides using multistage mass spectrometry (MS(n

145 Recent epidemiological studies link Periodontal disease(PD) to age-related macular dege

146 Cases were identified from linked pertussis notifications and each matched to 3 con

147 ivate T cells with solution ligands by cross-linking pMHC or using multivalent antibodies to TCR.

148 P mediates clearance of Huntington's disease-linked polyQ protein aggregates.

149 Link prediction in a complex network is a problem of fun

150 te distance, we design a new embedding-based link prediction method called global and local integrate

151 elop in Wiskott-Aldrich syndrome (WAS), an X-linked primary immunodeficiency disorder (PID) resulting

152 d ChIA-PET and HiChIP loops as well as loops linking promoters to regulatory elements.

153 d-ala-d-ala and reduced peptidoglycan cross-linking, prompting us to investigate synergism between b

154 ) is a complex and dynamic meshwork of cross-linked proteins that supports cell polarization and func

155 and 14 713 additional variants supported by linked-read data were identified.

156 ons, 26 of which are physically phased using linked-read sequencing.

157 land's fisheries is needed to quantitatively link reef degradation to stock production parameters is

158 Photochemical cross-linking reveals that the baboon amylin, like human amyli

159 These data provide evidence linking risk-associated variation to genes that may cont

160 The promiscuity of SPT therefore links serine and mitochondrial alanine metabolism to mem

161 t is a critical component of focal adhesions linking signaling between the extracellular matrix and t

162 ing the skin pH and urges for larger studies linking skin pH and skin S aureus abundance to understan

163 In the context of emerging evidence linking sphingolipid biology with cardiovascular pathoph

164 t earlier findings on the role of GORASPs in linking stacks, and we suggest that unlinking of stacks

165 The cumulative science linking stress to negative health outcomes is vast.

166 rmed with data collected from 2 separate but linked studies.

167 acoustically selective TeA neurons that help link the calls to a discriminative maternal behavioral r

168 Integrin-based focal adhesion complexes link the glial membrane to the extracellular matrix, but

169 tochastic mathematical model was proposed to link the in vitro and in vivo evolution of prostate canc

170 This suggestion is based on an attempt to link the interventions being facilitated by SER, the par

171 ntal pathogen, and several lines of evidence link the presence of this bacterium in the circulation w

172 Emerging evidence has linked the transcription factor RE1-silencing transcript

173 n via weak metal-ion binding, quantitatively linking the contributions of specific interactions of me

174 -Ph-C(60) (n = 0, 3, 5), were constructed by linking the fullerene (C(60)) and bis(3,4,5-trimethoxyph

175 ty is strongly affected by the geometry that links the environment to the sensory epithelium.

176 e remainder of the cardiovascular system and linked them to anti- and pro-thrombotic effects of aspir

177 andidate cis-regulatory elements (cCREs) and linked them to putative target genes.

178 es featuring voltage-dependent Ca2+-channels link these outputs to the downstream dynamics and can in

179 The molecular mechanisms that link these pathways, however, remain poorly understood.

180 onse, via phosphorylation of eIF2alpha, thus linking these pathways.

181 dynamics and plasticity, and the mechanisms linking these two phenomena, remain poorly understood.

182 mer and characterize the historical 'missing link' through which the modern tetramer evolved-a noncoo

183 nker alpha-actinin-4 and show that the cross-linking time of alpha-actinin-4 homodimers increases app

184 of complex datasets through functions which link to a powerful and interactive visualization user in

185 ndividual populations, but there is no clear link to estrogen pollution.

186 cosylation pattern and provide a mechanistic link to increased ROS release by neutrophils.

187 rophils into alveolar spaces, which might be linked to a decrease in the production of pro-inflammato

188 vir was described by a two-compartment model linked to a fetal and breastmilk compartment.

189 at rivaroxaban's antithrombotic potential is linked to a hitherto unknown rivaroxaban effect that imp

190 PARalpha), suggesting that FATP2 activity is linked to a PPARalpha-specific proximal ligand.

191 ugar-sweetened beverage (SSB) consumption is linked to adverse health outcomes.

192 Substance abuse disorders are linked to alteration of circadian rhythms, although the

193 ows high metabolic stability in all species, linked to an adequate pharmacokinetic profile in rodents

194 s in the homolog of the human CYFIP1, a gene linked to autism and schizophrenia, exhibit mitochondria

195 iratory syndrome corona virus 2 pneumonia is linked to both acute respiratory distress syndrome and s

196 assimilation by plants may be symmetrically linked to carbon (C) transfer from plant to fungus or go

197 particulate matter < 2.5u (PM(2.5)) has been linked to cardiopulmonary disease.

198 critical cellular "second messenger," may be linked to changes in cellular architecture that favor pa

199 use frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) and can contribute to

200 us progress in identifying genetic anomalies linked to clinical disease.

201 Periodontal disease has been linked to coronary heart disease (CHD), but studies have

202 in the central nervous system (CNS) has been linked to demyelination and remyelination.

203 paB signaling that has never previously been linked to density-dependent proliferation.

204 iad of cellular processes in plants that are linked to development, environmental responses and immun

205 ncluding mutations in ZDHHC genes, have been linked to different neurological pathologies and cancers

206 ing in the single T. cruzi mitochondrion are linked to differentiation by a yet-unknown signaling mec

207 including Alzheimer's disease, inextricably linked to disease onset and progression.

208 around specialist hospital centres that are linked to district general hospitals by operational deli

209 Macrophages have been linked to ductal development in the virgin mammary gland

210 ts of Poland; maternally the individuals are linked to earlier Neolithic lineages, whereas on the pat

211 s exhibit enhanced activation of brain areas linked to emotional processing during the trust game.

212 aracterized by elevated resting flow that is linked to enhanced NOS activity.

213 idual differences in dogmatism, a phenomenon linked to entrenched beliefs in political, scientific, a

214 ackground warmth of the early Eocene, likely linked to eruptive phases of the North Atlantic Igneous

215 S clusters in the chloroplast and cytosol is linked to Fe homeostasis in plants.

216 In addition, these events have been linked to flash droughts and can play a critical role in

217 phorylation prior to metabolism and has been linked to GAS pathogenesis.

218 Relative control of HIV-1 infection has been linked to genetic and immune host factors.

219 TDP-43, tau and amyloid-beta have all been linked to hippocampal atrophy.

220 for reliably assessing Pb emissions directly linked to human activities.

221 mber of the alpha-arrestin family previously linked to human obesity.

222 l basal ganglia tissue iron levels have been linked to impaired cognition in iron deficient children

223 s or in humans, whereas benzodiazepines were linked to increased risks of dementia.

224 e of intracellular aggregates, which was not linked to increased translation of IgG mRNA, but rather

225 d by cytochrome P450 (CYP) enzymes have been linked to increased tumor growth and metastasis, largely

226 scribe a specific example of a gAP in humans linked to individual differences in the response to stre

227 we have established the eicosanoid profiles linked to inhibition of COX-1 in platelets and in the re

228 Hypomagnesemia has been linked to insulin resistance through reduced tyrosine ki

229 This review describes the cellular pathways linked to IRF3 activation and where those pathways are t

230 2 and identify a specific evolutionary event linked to its appearance.

231 ma-associated herpesvirus (KSHV) is causally linked to Kaposi's sarcoma and several lymphoproliferati

232 known to affect mechanical gating and may be linked to large variability in tension sensitivity among

233 irst-cycle capacity loss is a kinetic effect linked to limited Li mobility at x > 0.88, with near ful

234 t not of IgG or IgA against FceRIalpha, were linked to low blood basophil (r = .414, P = .021) and eo

235 Phacoemulsification has been linked to lowered intraocular pressure (IOP) in patients

236 These assemblies were tightly linked to LTB(4) formation.

237 s which have become public health priorities linked to major hospital outbreaks and the recent emerge

238 ities, or number sense, has been recurrently linked to mathematical skills, although the nature of th

239 Gonadal hormones are linked to mechanisms that govern appetitive behavior and

240 ked if this tissue-dependent persistence was linked to MHC expression.

241 , 0.59; 95% CI, 0.37-0.93) were particularly linked to myocardial infarction, whereas high HDL oxidat

242 these asymmetric domain arrangements are not linked to negative cooperativity and hemiphosphorylation

243 e pre-mRNA that is alternatively spliced and linked to neurodegenerative diseases is tau (microtubule

244 els and interleukin-6 levels (which has been linked to nonosmotic release of vasopressin) was assesse

245 Beverage purchases were linked to nutritional information at the product level,

246 dentified a subset of phenotypes that can be linked to p120-catenin in epithelial integrity and turno

247 were strongly correlated with habitat shifts linked to particular soil conditions; 81.7% of edaphic v

248 -cell fusion (syncytium formation), which is linked to pathogenicity.

249 ed resources, a lookup database and web tool linked to PEATmoss was implemented.

250 ocus group discussions that are most closely linked to policy changes and descriptive analyses of the

251 imordial dwarfism in domesticated animals is linked to positive selection in minor spliceosome compon

252 genes in nuclear space has been extensively linked to regulation of gene expression, but the mechani

253 and lysine-27 tri-methylation (H3K27me3) are linked to repression of gene expression, but the functio

254 graphic rates, which in herbivores are often linked to resource-driven variation in body condition.

255 or optic nerve, and if such changes could be linked to SANS.

256 erarchical structures containing logic gates linked to self-immolative motifs.

257 Heart failure has previously been linked to sleep disorders that are often associated with

258 of cosmic rays which are themselves directly linked to solar activity and the earth magnetic field.

259 y of which whose presence in blood is likely linked to specific cell-level pathologic processes.

260 Astrocyte dysfunctions are also linked to synapse pathologies associated with neurodevel

261 vely, our data suggest that mTOR activity is linked to T-bet in Ag-expCD4(+) T cells but that reducti

262 overexpression of different efflux pumps is linked to the impairment of the quorum sensing (QS) resp

263 gates, suggesting that fibril disassembly is linked to the increased rate of peptidyl-prolyl isomeris

264 northeastern Massachusetts were molecularly linked to the outbreak.

265 ttacks on prejudiced attitudes toward groups linked to the perpetrators as the cause of this increase

266 Many of these phytochemicals have been linked to the prevention and management of several chron

267 r 1950-2010 is externally forced and largely linked to the representation of volcanic aerosols.

268 cells and monocytes, respectively, which was linked to the severity of monocyte subset alterations.

269 tworks associated with adaptive immunity was linked to the suppression of networks for tight junction

270 observed for dyads containing BP covalently linked to thymidine, the aim of this work is to investig

271 nzymatic regulators of biochemical reactions linked to transmethylation and polyamine metabolism.

272 stress granule-associated proteins have been linked to various neurodegenerative diseases.

273 a massive collapse of terrestrial ecosystems linked to volcanism-driven environmental change triggere

274 The medial frontal cortex has been linked to voluntary action, but an explanation of why de

275 These two genes are not physically linked to wing-color pattern loci or other genomic regio

276 tems are sharing information about genes and linking to associated diseases.

277 troviral therapy (ART)-eligible adults newly linking to care at 64 clinics in Zambia between 1 April

278 Gene regulatory networks (GRNs) link transcription factors (TFs) to their target genes a

279 nds Lys(11)-, Lys(48)-, Lys(63)-, and Met(1)-linked ubiquitin chains in vitro, establishing UBA(Cez)

280 lates cellular homeostasis by inhibiting K63-linked ubiquitination of beclin 1 mediated by TRAF2, cIA

281 Growing literature linking unconventional natural gas development (UNGD) to

282 dontitis, has been proposed as the microbial link underlying this association.

283 nction and for robust evaluation of diseased-linked variants of formin.

284 ales act as resonant (5) unit cells that are linked via a shared wing membrane to form this metamater

285 Moreover, a positive link was identified between IA and posttransplant bacter

286 ion, the hub-set-orientation prevalence of a link, which indicates its average orientation with respe

287 ctions through SEPT9-dependent F-actin cross-linking, which enables the generation of F-actin bundles

288 CDH15) and cadherin-23 (CDH23), form the tip-links, whose tension gates the hair cell mechanoelectric

289 Aortic stiffness is closely linked with cardiovascular diseases (CVDs), but recent s

290 t Si-governed mitigation of Buta toxicity is linked with favorable modifications in energy flux param

291 The greater complexity of eukaryotes is linked with larger genomes and we demonstrate that the b

292 Data were linked with national registers for hospital admissions,

293 d with the subsequent stage) if the approach linked with the current stage proves to be unfeasible, a

294 stic outcomes of many cancer types have been linked with the expression levels of several of these ar

295 nfections occurred across the UK ICU network linked with the first few years of a national infection

296 riations in the TLR10/1/6 locus appear to be linked with the risk of contracting a bloodstream infect

297 aptic tracing indicates extensive disynaptic links with cognitive, affective, and motor forebrain cir

298 ight on the genetics of early growth and its links with later-life health outcomes.

299 complex multi-cellular organ that intimately links with the cardiovascular system to accomplish gas e

300 tionships under global changes, and call for linking within-species responses to interspecific coordi