ライフサイエンスコーパス: lipid raft

1 ellular membranes in clusters, often called 'lipid rafts'.

2 s enriched in cholesterol and sphingolipids (lipid rafts).

3 ar structures such as membrane microdomains (lipid rafts).

4 e dissolution of ordered microdomains (i.e., lipid rafts).

5 ioned as a cell-signaling receptor system in lipid rafts.

6 integral membrane proteins and formation of lipid rafts.

7 ontaining high concentrations of sterol-rich lipid rafts.

8 s of naturally occurring nanodomains such as lipid rafts.

9 n kinase C activities, and both clathrin and lipid rafts.

10 40 nm that are consistent with the notion of lipid rafts.

11 ding ordered, lipid-driven assemblies termed lipid rafts.

12 hat achieves full activity when recruited to lipid rafts.

13 pressant treatment translocates Galphas from lipid rafts.

14 n filaments and microtubules but also affect lipid rafts.

15 FC may be incorporated into microdomains or lipid rafts.

16 urally diverse antidepressants accumulate in lipid rafts.

17 ments, the M-PMV MA did not co-localize with lipid rafts.

18 in membrane structure in unique regions like lipid rafts.

19 itol (GPI)-anchored proteins localize in the lipid rafts.

20 its generation can modulate the structure of lipid rafts.

21 cid) had markedly less Tlr4 recruitment into lipid rafts.

22 d proteins on leukocytes that associate with lipid rafts.

23 and platinum colocalized with FAS protein in lipid rafts.

24 nslocation of the GDNF receptor complex into lipid rafts.

25 forces play a major role in the formation of lipid rafts.

26 ead to the formation, stability, and size of lipid rafts.

27 hrough caveolae, membrane invaginations from lipid rafts.

28 -beta-cyclodextrin (MbetaCD), which disrupts lipid rafts.

29 proper membrane anchoring and trafficking to lipid rafts.

30 raction with cholesterol present in membrane lipid rafts.

31 protein (APP) and gamma-secretase levels in lipid rafts.

32 regulating amyloidogenic pathway proteins in lipid rafts.

33 ransport of galactosylceramide from Golgi to lipid rafts.

34 e endosome and its proteolytic activation in lipid rafts.

35 ed with the beta-glucan receptor dectin-1 in lipid rafts.

36 as well as on their lateral accumulation in lipid rafts.

37 e we show that soluble klotho binds membrane lipid rafts.

38 oteins normally restricted to juxtaparanodal lipid-rafts.

39 al synapse, where it regulates filamin A and lipid raft accumulation, as well as T cell activation, i

40 Mechanical disruption of the lipid rafts activates PLD2 by mixing the enzyme with its

41 ing that HtrA and p66 may reside together in lipid rafts also.

42 diethyl ether, xenon, and propofol, disrupt lipid rafts and activate PLD2.

43 indomethacin (IND) leads to the formation of lipid rafts and activation of caveolin-1; however, no su

44 Importantly, LMP1 trafficking to lipid rafts and activation of NF-kappaB and PI3K/Akt pat

45 The distribution of membrane lipid rafts and adhesion receptors were analyzed by imag

46 nds the HIV-1 Gag polyprotein, retains it in lipid rafts and blocks HIV-1 virion production and sprea

47 essential constituents of cell membranes and lipid rafts and can modulate signal transduction events.

48 vitro and in vivo demonstrate that membrane/lipid rafts and caveolin (Cav) organize progrowth recept

49 een LMP1 and these proteins was localized to lipid rafts and dependent on LMP1 signaling.

50 In addition, the interplay between lipid rafts and different modes of cancer cell death, in

51 two classes of antidepressants accumulate in lipid rafts and effect translocation of Galphas to the n

52 and patient IgG colocalized with markers for lipid rafts and endosomes.

53 miR-33 augments macrophage lipid rafts and enhances proinflammatory cytokine induct

54 f amyloid precursor protein (APP) and Tau to lipid rafts and increased the abundance of these protein

55 ivated Toll-like receptors (TLRs) cluster in lipid rafts and induce pro- and anti-tumor responses.

56 ynitrite drove TLR4 recruitment into hepatic lipid rafts and inflammation, whereas the in vivo use of

57 a2-3-sialyllactose moiety of gangliosides in lipid rafts and inhibition of raft-dependent signaling u

58 mAb, lacks the ability to redistribute into lipid rafts and is glycoengineered for augmented antibod

59 lum (ER) membrane protein that is located in lipid rafts and known to be important in ER-associated p

60 location of normal prion protein (PrP(C)) in lipid rafts and lipid cofactors generating infectious pr

61 We observed that SFK and FAK in the lipid rafts and nonrafts are differently regulated by fl

62 Kv1.3 localizes in lipid rafts and participates in the immunological respon

63 ynamics and clustering of SR-B1 contained in lipid rafts and potently inhibits cellular exosome uptak

64 induced localization of TRAF6 and c-SRC into lipid rafts and preventing nuclear accumulation of trans

65 ctively, elucidation of the complex roles of lipid rafts and raft components within the metastatic ca

66 n of phospholipase D2 (PLD2) localization to lipid rafts and subsequent production of signaling lipid

67 monstrated that tubulin anchors Galpha(s) to lipid rafts and that increased tubulin acetylation (due

68 two distinct adaptors, Flot-1 in noncaveolar lipid rafts and the AP2A1/2 complex in clathrin vesicles

69 oscopy, we characterized the distribution of lipid rafts and the E-selectin counterreceptor CD44 on t

70 s able to form GM1- and cholesterol-enriched lipid rafts and these raft domains are important for enc

71 re, we confirmed that US9 is associated with lipid-rafts and can target functional enzymes to membran

72 rane organization into more ordered (L(o) or lipid raft) and more disordered (L(d)) domains.

73 We find that apoA1 rapidly disrupts membrane lipid rafts, and as a consequence, dampens the PI3K/Akt

74 holesterol-rich membrane microdomains called lipid rafts, and can be blocked by non-specific depletio

75 ng ATP, protein kinase A or the formation of lipid rafts, and does not require ion flux through the c

76 evels, increases membrane fluidity, disrupts lipid rafts, and redistributes CD44, which is the primar

77 by preventing phagolysosomal maturation in a lipid raft- and O antigen-dependent manner.

78 Here we show that lipid rafts are dynamic compartments that inactivate the

79 Lipid rafts are hypothesized to facilitate protein inter

80 upport the notion that sialogangliosides and lipid rafts are membrane receptors for sKlotho and that

81 Lipid rafts are specialized dynamic microdomains of the

82 Lipid rafts are submicron proteolipid domains thought to

83 Lipid rafts are tightly packed, cholesterol- and sphingo

84 Lipid rafts are widely believed to be an essential organ

85 esistant membrane nanodomains, also known as lipid rafts, are the primary response element in EF sens

86 ect parallels the movement of Galphas out of lipid rafts as determined by cold detergent membrane ext

87 evidence that this is through regulation of lipid rafts as Lrch4 silencing reduces cell surface gang

88 &HNF4alpha on CPT2, the lipid droplet and ER-lipid-raft associated PLIN3 and Erlin1.

89 oichiometries of intact Nanodiscs containing lipid-raft associated sphingomyelin.

90 These Ia.2(+) class II conformers are lipid raft-associated and able to drive both tyrosine ki

91 -Src downregulated the expression of Pag1, a lipid raft-associated inhibitor of Src, which was restor

92 n of NS2 with Core and endoplasmic reticulum lipid raft-associated protein 2 (Erlin-2).

93 ed by affinity purification, we detected the lipid raft-associated proteins flotillin-1 and flotillin

94 knock-down suppresses the expression of the lipid raft-associated proteins VE-cadherin and caveolin-

95 olutionary conserved, ubiquitously expressed lipid raft-associated scaffolding protein.

96 In summary, this study identifies AnxA2 as a lipid raft-associated trafficking factor for NKCC2 and p

97 To identify novel lipid-raft-associated CXCR4 regulators supporting invasi

98 ulted in the defective expression of over 60 lipid-raft-associated surface receptors, and impaired BC

99 ed with Dex treatment alone, suggesting that lipid raft association of the GR has a role in enhancing

100 e lack of BACE1 S-palmitoylation and reduced lipid raft association.

101 Inhibition of FAK in the lipid rafts blocked SFK response to fluid flow, while in

102 tif resulted in the exclusion of D(1) R from lipid rafts, blunted cAMP response, impaired sodium tran

103 activation of PDGFR specifically located in lipid rafts but not outside rafts, implying the role of

104 X7 receptors associate with cholesterol-rich lipid rafts, but it is unclear how this affects the prop

105 Ralpha colocalized with GM1 ganglioside-rich lipid rafts, but MHC I clusters retracted to smaller sub

106 phenotype was accompanied by a reduction of lipid rafts, but was independent of the peroxisomal or t

107 Kidney-restricted disruption of lipid rafts by beta-MCD jettisoned the D(1) R from the b

108 Therefore, the recruitment of Ret into lipid rafts by GFRalpha1 is required for the physiologic

109 n of neuronal cholesterol trafficking and of lipid rafts by Nef may contribute to early stages of neu

110 Lipid raft/caveolae disruptors (methyl-beta-cyclodextrin

111 ed liposomes was dominantly mediated via the lipid raft/caveolae endocytic pathway.

112 anti-oxidant and signaling molecule, through lipid raft/caveolae-dependent processes.

113 ular compartmentalization of Nox isoforms in lipid rafts/caveolae and assessed the role of these micr

114 mulation induced trafficking into and out of lipid rafts/caveolae for Nox1 and Nox5 respectively.

115 We identify an important role for lipid rafts/caveolae that act as signaling platforms for

116 Whether cholesterol-rich microdomains (lipid rafts/caveolae) are involved in these processes is

117 al function in uninfected cells to fine-tune lipid raft cholesterol that regulates innate immunity to

118 R proinflammatory responses due to augmented lipid raft cholesterol.

119 cell surface glycosaminoglycans and induces lipid raft clustering, increasing the incorporation of C

120 naling and internalization by disrupting BCR-lipid raft coclustering and by inducing the endocytosis

121 to be tightly regulated by cholesterol-rich "lipid rafts." Collectively, these data show that RIDalph

122 ncy clearly increased cell-surface levels of lipid raft components in detached fibroblasts, which mig

123 rinuclear tubular structures, an increase of lipid raft components, and increased lipid raft partitio

124 is defective Ret signaling owing to improper lipid raft composition or function.

125 sion of CD1d accompanied by an alteration in lipid raft content on the plasma membrane of thymocytes

126 ANGPTL4-deficient CMPs have higher lipid raft content, are more proliferative and less apop

127 ses in cellular and membrane cholesterol and lipid raft contents as determined by Raman spectroscopy

128 oscale assemblies in cell membranes known as lipid rafts, coself-assembly of 1-decanol into cetyltrim

129 Galpha(s), when ensconced in lipid rafts, couples less effectively with adenylyl cycl

130 elocytic leukemia (APL), NTAL depletion from lipid rafts decreases cell viability through regulation

131 and fusion, and through macropinocytosis and lipid raft-dependent endocytosis.

132 HMVEC-d), its naturalin vivotarget cells, by lipid raft-dependent macropinocytosis.

133 cells could mediate HCV RNA replication in a lipid raft-dependent manner, as the depletion of cholest

134 Annexins mediate lipid raft-dependent trafficking of transmembrane protei

135 LAC-based quantitative proteomic analysis of lipid-rafts derived from PC3 stable cell lines with over

136 In addition, the EPA-induced lipid raft disorganization, caveolin-1 inactivation, and

137 s, and provide cytoprotection, consequent to lipid raft disorganization.

138 was cell-contact dependent and unaffected by lipid raft disruption of donor TEC.

139 ed cholesterol release from cells, increased lipid-raft disruption, decreased phosphatidylserine (PS)

140 Pretreatment with lipid raft disruptor (Methyl-beta-cyclodextrin, MbetaCD)

141 NHE3 complex formation and changes the NHE3 lipid raft distribution, which cause changes in specific

142 dentified proteins and LMP1 was localized to lipid raft domains and was dependent on LMP1-induced sig

143 LMP1 is localized to lipid raft domains to induce signaling.

144 or 15 min, which translocated Galpha(s) from lipid raft domains to non-raft domains.

145 iates with TLR4 and translocates to membrane lipid raft domains.

146 entially associates with cholesterol to form lipid raft domains.

147 suicide brain showed increased Galpha(s) in lipid-raft domains compared with normal subjects.

148 d the increased localization of Galpha(s) in lipid-raft domains responsible for attenuated cAMP signa

149 ting increased sequestration of Galpha(s) in lipid-raft domains, where it is less likely to couple to

150 fe cycle stages possess chemically different lipid rafts due to different sterol utilization.

151 The trafficking behavior of the lipid raft-dwelling US9 protein from Herpes Simplex Viru

152 hosphodiesterase acid-like 3b (SMPDL3b) is a lipid raft enzyme that regulates plasma membrane (PM) fl

153 ent of TCR-associated signaling molecules to lipid rafts, followed by abrogation of protein tyrosine

154 Our results highlight the essential role of lipid rafts for effective D(1) R signaling.

155 ructural features that allow it to reside in lipid rafts for its activity.

156 iting various niche signaling molecules into lipid rafts for promoting neuronal differentiation of NS

157 The forces that drive lipid raft formation are poorly understood.

158 of switch-activated protein 70 (SWAP-70) in lipid raft formation of dendritic cells.

159 been largely overlooked as major players in lipid raft formation.

160 ly, CRFR1 and gamma-secretase co-localize in lipid raft fractions, with increased gamma-secretase acc

161 aracterized the lipid and protein content of lipid rafts from control E. huxleyi cells and those infe

162 pletion of cholesterol, a major component of lipid rafts, from autophagosomes abolished HCV RNA repli

163 GM3, a lipid raft ganglioside synthesized by GM3 synthase (GM3S

164 ce statement: Membrane microdomains known as lipid rafts have been proposed to be unique subdomains i

165 Based on in vitro studies, lipid rafts have been reported to be necessary for the f

166 dered membrane domains, often referred to as lipid rafts, have been highly debated by cell biologists

167 Since cholesterol is a critical component of lipid rafts, here we tested the hypothesis of whether th

168 The lipid raft hypothesis postulates that lipid-lipid intera

169 The lipid raft hypothesis presents insights into how the cel

170 This was associated with increased lipid rafts in APOepsilon3/APOepsilon4 monocytes.

171 istently, GFRalpha1 correctly partitioned to lipid rafts in brain tissue.

172 y much resembles the assembly process of the lipid rafts in cell membranes and triggers orders of mag

173 cAMP (Galphas) is increasingly localized to lipid rafts in depressed subjects and that chronic antid

174 a GFRalpha1, the existence and importance of lipid rafts in GDNF-Ret signaling under physiologic cond

175 scopy showed that S. aureus colocalized with lipid rafts in HMEECs.

176 1 cascade, which requires Fyn-Src kinase and lipid rafts in human taste bud cells (TBCs).

177 central role for SR-A complexes in epidermal lipid rafts in mediating the uptake of nucleic acid-lade

178 is possibility and also points to a role for lipid rafts in milk product secretion.

179 x and increasing the abundance and modifying lipid rafts in neuronal plasma membranes.

180 ke receptor (TLR)-4 recruitment into hepatic lipid rafts in nonalcoholic steatohepatitis (NASH) are u

181 nce of specialized signalling domains called lipid rafts in schistosomes and propose that correct sig

182 esides in detergent-resistant outer membrane lipid rafts in which conversion to the pathogenic misfol

183 ced NHE3 complex size, reduced expression in lipid rafts, increased BB mobile fraction, and reduced b

184 klotho regulates TRPC6 calcium signaling via lipid rafts, independent of the FGFR-FGF23 pathway.

185 ellular factors (e.g. actin cytoskeleton and lipid rafts) influence the assembly of ligand-receptor c

186 B cell receptors (BCRs), a process requiring lipid rafts, interferes with PM repair.

187 abundance of caveolae, which are specialized lipid raft invaginations of the plasma membrane associat

188 t Tax recruitment of autophagic molecules to lipid rafts is a dominant strategy to deregulate autopha

189 est that the translocation of Galpha(s) from lipid rafts is a reliable hallmark of antidepressant act

190 s we show that clustering of gangliosides in lipid rafts is important.

191 dy suggest that the association of LMP1 with lipid rafts is mediated at least in part through interac

192 s suggests that the association of LMP1 with lipid rafts is mediated through interactions with actin-

193 cavenger receptor type B-1 (SR-B1), found in lipid rafts, is a receptor for cholesterol-rich high-den

194 , and C24:0) in central nervous system (CNS) lipid rafts isolated without using detergent.

195 into cholesterol-rich membrane microdomains (lipid rafts), its compartmentalization has not been demo

196 , which reduced IFNG signaling by disrupting lipid rafts, leading to reduced phosphorylation (activat

197 th a clustering of CD44 and CD24 in membrane lipid rafts, leading to the activation of Src Family Kin

198 The MAM region of the ER is a lipid raft-like domain closely apposed to mitochondria i

199 This is complicated by HA and NA residing in lipid raft-like domains, whereas M2, although an integra

200 In particular, mitochondrial lipid raft-like microdomains appear to function as platf

201 Mitochondrial lipid raft-like microdomains, experimentally also termed

202 it mitochondrial antiviral signaling through lipid raft-like microdomains.

203 a complement-independent manner and required lipid raft localization for CSC maintenance and cisplati

204 hippocampal expression of Cav-1 and membrane/lipid raft localization of postsynaptic density protein

205 glioside is a major constituent of mammalian lipid rafts (LRs) and known to react with cholera toxin

206 ion, the membrane region of cholesterol-rich lipid raft markedly weakens the membrane association of

207 opus pronephric kidney were positive for the lipid raft markers ganglioside GM1 and Caveolin-1.

208 or cell electrosensing and provide a role in lipid raft mechanotransduction.

209 ndicate that MCPyV enters cells via caveolar/lipid raft-mediated endocytosis but not macropinocytosis

210 Both clathrin- and caveolae/lipid raft-mediated endocytosis pathways are involved in

211 alization proceeds via clathrin-independent, lipid raft-mediated endocytosis.

212 Furthermore, macropinocytosis and lipid raft-mediated were shown here as mechanisms of MkM

213 Lrch4 promotes proper docking of LPS in lipid raft membrane microdomains.

214 hole-tissue homogenate, plasma membrane, and lipid-raft membrane domains in tissue from normal contro

215 Non-T cell activation linker (NTAL) is a lipid raft-membrane protein expressed by normal and leuk

216 cysteine residue enables Fas to localize to lipid raft microdomains and induce apoptosis in cell lin

217 Many channels localize in lipid raft microdomains, which are enriched in cholester

218 complex containing Beclin1 and Bif-1 to the lipid raft microdomains.

219 n with no cytosolic domain that localizes to lipid raft microdomains.

220 ber of the MAGUK family, recruits Kv1.3 into lipid-raft microdomains and protects the channel against

221 in vitro demonstrate that neuronal membrane/lipid rafts (MLRs) establish cell polarity by clustering

222 Membrane lipid rafts (MLRs) within the plasma membrane of most ce

223 mmal signaling microdomains, termed membrane/lipid rafts (MLRs).

224 ranged cholesterol distribution and aberrant lipid raft morphology, supporting an unrecognized role f

225 These findings illuminate differences in the lipid rafts of an organism employing life cycle-specific

226 geting glycoprotein ligands for selectins to lipid rafts of leukocytes.

227 ters with interleukin-2 and -15 receptors in lipid rafts of T cells.

228 holesterol metabolism is pathogens targeting lipid rafts of the host plasma membrane.

229 conclude that VHH JM4, when targeted to the lipid rafts of the plasma membrane, efficiently neutrali

230 attachment signal, VHHs are targeted to the lipid rafts of the plasma membranes.

231 attachment signal, VHHs are targeted to the lipid rafts of the plasma membranes.

232 known how these glycoproteins associate with lipid rafts or whether this association is required for

233 embranes by inducing several signals through lipid raft organization after membrane incorporation, wh

234 ease of lipid raft components, and increased lipid raft partitioning of APP.

235 LMP1 signaling requires oligomerization, lipid raft partitioning, and binding to cellular adaptor

236 Current models of lipid rafts propose that lipid domains exist as nanoscal

237 tected in the miRNA-rich-EVs, suggesting the lipid raft protein as a biomarker of EV-miRNA enrichment

238 ll population of the GR co-localize with the lipid raft protein flotillin-1 (Flot-1) at the plasma me

239 Notably, caveolin-1, a lipid raft protein, is exclusively detected in the miRNA

240 nce of specialized membrane domains, such as lipid rafts, protein-lipid complexes, receptor complexes

241 odel is proposed, in which CYP46A1-dependent lipid raft rearrangement and subsequent decrease of prot

242 e latter ones often called lipid domains or "lipid rafts." Recent findings highlight the dynamic natu

243 isms by which membrane microdomains, such as lipid rafts, reduce these effects, and thus, enhance ass

244 , properties, and even the very existence of lipid rafts remain unresolved.

245 The receptor for GDNF comprises the lipid raft-resident, glycerophosphatidylinositol-anchore

246 to the translocation of the TRAF2 complex to lipid rafts, resulting in its degradation and activation

247 with one another because of competition for lipid rafts, revealing how frequent membrane injury and

248 P90, and HER2 within specific actin-rich and lipid raft-rich membrane signaling domains.

249 Here, we show that the lipid raft scaffolding protein caveolin-1 interacts with

250 Instead, lipid rafts shifted disordered CTA1 to a folded conforma

251 estingly, inhibition of myosin-9, actin, and lipid-rafts, shown to be involved in PNX1-hemichannel fu

252 ar cholesterol and disrupted plasma membrane lipid rafts, similar to positive control methyl-beta-cyc

253 Lipid rafts, specialized membrane microdomains in the pl

254 The clinical role of lipid raft-specific proteins, caveolin and flotillin, in

255 ling a dynamic spatiotemporal control of the lipid raft structure with light.

256 ol-glycolipid-rich membrane regions known as lipid rafts, suggesting that HtrA and p66 may reside tog

257 h the colocalization of platinum with FAS in lipid rafts support an extrinsic apoptotic signaling mec

258 Moreover, expression of lipid raft-targeted Bif-1 or Beclin1 was sufficient to i

259 cytoskeleton necessary for the clustering of lipid rafts, TCR, and costimulatory receptors toward the

260 This very much resembles the role of the lipid rafts that sharply increases the reaction rate of

261 l in which GFRalpha1 is no longer located in lipid rafts, that the developmental functions of GDNF in

262 omyelin, cholesterol, and select proteins in lipid rafts-the dynamic functional subdomains of the pla

263 sion by EZCs reduces movement of BMPR1b into lipid rafts, thereby limiting the known deleterious effe

264 alized functional SR-As to FLOT-1-containing lipid rafts throughout the epidermis and CAV-1-containin

265 HGAL phosphorylation and redistribution from lipid raft to bulk membrane and cytoplasm, followed by d

266 ntagonist did not translocate Galpha(s) from lipid raft to non-raft domains.

267 ed that HCV could induce the localization of lipid rafts to autophagosomes to mediate its RNA replica

268 Our results identify ganglioside-enriched lipid rafts to be receptors that mediate soluble klotho

269 s enveloped viruses utilize cholesterol-rich lipid rafts to bud from the host cell membrane, and it i

270 llactose-containing gangliosides enriched in lipid rafts to inhibit raft-dependent PI3K signaling.

271 used as a tool to study the contribution of lipid rafts to neurodegenerative disease conditions wher

272 at ketamine would translocate Galpha(s) from lipid rafts to non-raft microdomains, similarly to other

273 gered relocalization of gamma-secretase from lipid rafts to nonlipid rafts where it cleaved Notch.

274 echanistically, uPAR sequestered TACE within lipid rafts to prevent Notch1 activation, thereby promot

275 exosomal LMP1 release that is distinct from lipid raft trafficking.

276 biosensor was further targeted in or outside lipid rafts via different lipid modification signals.

277 in vitro is augmented by translocation into lipid rafts via GFRalpha1, the existence and importance

278 ed with HAND was lower, and the abundance of lipid rafts was higher compared with HIV-negative indivi

279 To explain why klotho preferentially targets lipid rafts we show that clustering of gangliosides in l

280 signaling is dependent on CD44 clustering in lipid rafts, we pretreated animals with methyl-beta-cycl

281 to specifically modify Galphas localized to lipid rafts, we sought to determine whether structurally

282 In Ifitm3(-/-) B cells, lipid rafts were depleted of PIP3, which resulted in the

283 Expression and recruitment of TLR4 into the lipid rafts were significantly greater in rodent and hum

284 nexin A2, which are proteins associated with lipid rafts, were also identified.

285 ed rather than oxidized DJ-1 translocated to lipid rafts, where it associated with Lyn, an interactio

286 n recruitment to invadopodia is dependent on lipid rafts, whereas ezrin/moesin proteins mediate podop

287 Caveolae, specific lipid rafts which concentrate caveolins, harbor signalin

288 dence suggests that membrane domains, termed lipid rafts, which are enriched in sphingomyeline and ch

289 preferential localization of the receptor in lipid rafts, which are plasma membrane platforms replete

290 e activation is key in TLR4 recruitment into lipid rafts, which in turn up-regulates NF-kappaB transl

291 barrier depends heavily on the integrity of lipid rafts, which include sphingolipids as key componen

292 R4 gene expression and receptor signaling on lipid rafts, which induces protease expression and cance

293 east cancer cells form a complex in membrane lipid raft with caveolin-1 (CAV1) and focal adhesion kin

294 could specifically induce the association of lipid rafts with autophagosomes for its RNA replication.

295 The association of lipid rafts with autophagosomes was specific to HCV, as

296 Disruption of lipid rafts with cyclodextrin reversed the phenotype.

297 The association of lipid rafts with HCV-induced autophagosomes was confirme

298 cantly increased partitioning of BMPR1b into lipid rafts with increased SMAD1/5/8 and p38 signaling.

299 This review highlights the roles of lipid rafts within the metastatic cascade, specifically

300 tion by preventing translocation of AKT into lipid rafts without altering the activation of receptor-