ライフサイエンスコーパス: lipolytic

1 orescent PLA2 assay showed that hVPLA2 had a lipolytic action first on the outer plasma membrane and

2 PVN inhibited the lipolytic action of 0.1 microM isoproterenol by 88%, whi

3 We conclude that the lipolytic action of TNF-alpha is influenced by glucose i

4 Thus, the lipolytic action(s) of HSL at the LD surface requires PK

5 ) mobilization and determine the site of its lipolytic action, we performed time-lapse confocal micro

6 ood coagulation reactions independent of its lipolytic action.

7 er, these observations suggest that both the lipolytic actions of LPL and LPL-induced VLDL catabolism

8 esults provide novel insight into caffeine's lipolytic actions through autophagy in mammalian liver a

9 Akey step in lipolytic activation of adipocytes is the translocation

10 Given recent evidence for lipolytic activation of peroxisome proliferator-activate

11 sed hearts, consistent with a rate-dependent lipolytic activation of peroxisome proliferator-activate

12 ipase are continuously colocalized following lipolytic activation.

13 horylation of perilipin A engenders a 7-fold lipolytic activation.

14 domain (residues 389-448) to achieve maximal lipolytic activation.

15 iminished levels of COX-2 metabolites during lipolytic activation.

16 and Enterococcus faecalis emerged for their lipolytic activities and ability to release hydroxy- and

17 Similarly, despite post-heparin plasma lipolytic activities of 4495 +/- 534 and 4844 +/- 1336 n

18 enzamidine suggests that the proteolytic and lipolytic activities of PLA2 proceed through different m

19 adipocyte identity were increased, and basal lipolytic activities were significantly augmented in adi

20 ties of oil bodies and significantly reduced lipolytic activity (>90% enzyme inactivation), resulting

21 surface-exposed passenger domain exhibiting lipolytic activity (aa 62 to 330).

22 Total lipolytic activity after intensive treatment was unchang

23 effects of WAT-ECs on adipocytes, improving lipolytic activity and insulin sensitivity and reducing

24 children were accompanied by decreased basal lipolytic activity and significantly enhanced stromal va

25 Importantly, disruption of Zeb1-dependent lipolytic activity and/or membrane phospholipid remodeli

26 mutant of pancreatic sPLA(2) with decreased lipolytic activity as compared to wild-type sPLA(2).

27 nonpolar lipids, Tgl4p and Tgl5p lose their lipolytic activity but retain their side activity as lys

28 and properties of lipases affect survival of lipolytic activity during aboral gastrointestinal transi

29 rminus, and the significance of PlaB-derived lipolytic activity for L. pneumophila intracellular repl

30 However, the nature of the lipolytic activity has remained obscure.

31 The lipolytic activity in oil body creams as affected by rec

32 videnced by normal catecholamine release and lipolytic activity in response to cold stimulation.

33 d uptake of HDL particles independent of its lipolytic activity in vitro.

34 Lipolytic activity in whole wheat flour (WWF) is largely

35 To determine whether lipolytic activity is required for this effect, we also

36 Mutation of serine 404 did not alter the lipolytic activity of ATGL but did decrease CRPC growth,

37 on of perilipins at the LD surface regulates lipolytic activity of ATGL.

38 Lipolytic activity of EL, however, seems to be most impo

39 We have investigated the lipolytic activity of human serum using isolated rat adi

40 This results in decreased lipolytic activity of the enzyme.

41 These data link the anti-lipolytic activity of the HCV core protein with altered

42 McaP is involved in both the binding and the lipolytic activity of the molecule and demonstrate that

43 2 of McaP, predicted to be important for the lipolytic activity of the protein, resulted in loss of h

44 fects of these four stereoisomers toward the lipolytic activity of three microbial lipases: Fusarium

45 cles, along with favorable effects on plasma lipolytic activity through lipoprotein lipase-mediated c

46 of EL (EL-EL) was expressed and had similar lipolytic activity to EL.

47 n of PLA2, that is, a strong increase in the lipolytic activity upon binding to the surface of phosph

48 Partial purification of this lipolytic activity using gel filtration and ion-exchange

49 Lipolytic activity was absent in the null mutants, where

50 Exercise-induced AT lipolytic activity was significantly reduced in atATGL-K

51 ated that VAT-ECs provoked a decrease in the lipolytic activity, adipokine secretion, and insulin sen

52 ters, BatA, and demonstrate that it displays lipolytic activity, aids in intracellular survival, is e

53 and represses Foxo1 and Cgi58, activators of lipolytic activity, and forced expression of miR-145 att

54 , a metabolic homeostatic factor with strong lipolytic activity, are decreased in obese individuals.

55 hat two HL monomer subunits are required for lipolytic activity, consistent with an HL homodimer.

56 In addition to the increase in lipolytic activity, cytokine treatment was demonstrated

57 ne the smallest structural unit required for lipolytic activity, HL was subjected to radiation inacti

58 o exhibit dramatically attenuated stimulated lipolytic activity, indicating that perilipin is require

59 in WAT markedly reduced adrenergic-mediated lipolytic activity, likely through inactivation of the N

60 Aside from its lipolytic activity, LpL promotes lipoprotein uptake by i

61 up V and X PLA2s showed strong transcellular lipolytic activity, whereas group IIA PLA2 exhibited muc

62 The 148M mutant protein has reduced lipolytic activity, with attendant increased cellular tr

63 olism, regardless of the donor and degree of lipolytic activity.

64 tprandial TG and reduced post-heparin plasma lipolytic activity.

65 es even though they secreted as much or more lipolytic activity.

66 stable, with reduced cleavage and conserved lipolytic activity.

67 hesive properties of McaP do not require its lipolytic activity.

68 n of approximately 80 kDa contributes to the lipolytic activity.

69 olin-1 null mice exhibit markedly attenuated lipolytic activity.

70 d mitochondrial respiration and cAMP-induced lipolytic activity.

71 on of seven serine hydrolases with potential lipolytic activity.

72 ophospholipases and known inhibitors of this lipolytic activity.

73 ating that perilipin is required for maximal lipolytic activity.

74 s no correlation between bridge function and lipolytic activity.

75 d biochemical evidence that one of these has lipolytic activity.

76 ce in Adrb2 expression, as well as a greater lipolytic activity.

77 cause of the upregulation of genes promoting lipolytic activity.

78 Exposure of fat cells to lipolytic agents or external FFA results is a rapid intr

79 ot prevent the changes in pHi caused by FFA, lipolytic agents, or insulin.

80 ubstrate specific lipase that contributes to lipolytic and haemolytic activity in vitro and is requir

81 hin the active site, demonstrated attenuated lipolytic and haemolytic phenotypes when compared with t

82 These data clearly indicate that the lipolytic and hepatic responses to hypoglycemia are driv

83 3-L1 cells which may have contributed to the lipolytic and insulin-like activities observed in this s

84 man liver and adipose tissue, possesses both lipolytic and lipogenic activity in vitro and localizes

85 ed to undergo fragmentation and fusion under lipolytic and lipogenic conditions, respectively.

86 he diets appear to mediate these changes via lipolytic and lipogenic pathways in adipose tissue.

87 ed with reduced expression of genes encoding lipolytic and lipogenic proteins.

88 differences exist in adipocyte responses to lipolytic and lipogenic stimuli, in adipocyte apoptosis,

89 trates for the first time that EL has both a lipolytic and nonlipolytic function in HDL metabolism in

90 nal transduction pathways mediating the anti-lipolytic and prostaglandin D2/flushing pathways are dis

91 ially in strain CcI3, with more esterolytic, lipolytic and proteolytic enzymes having signal peptides

92 The production and release of lipolytic and proteolytic extracellular enzymes by P. ac

93 cortisol, endogenous glucose production, and lipolytic and symptom responses.

94 tory activity of full-length Angptl4 reveals lipolytic and thermogenic properties with therapeutic re

95 growth, but at the expense of diabetogenic, lipolytic, and hepatosteatotic consequences.

96 onents that are generated through oxidative, lipolytic, and proteolytic activities lead to the format

97 n5-Tg mice increased B-adrenergic signaling, lipolytic, and thermogenic protein expression in adipose

98 t in the endoplasmic reticulum seems to lack lipolytic as well as acyltransferase activity as shown b

99 pose tissue (iWAT), and adipose tissue lipid lipolytic assays to define the functional roles of hypot

100 lar impact of dysfunctional PPARgamma on the lipolytic axis and to explore whether these defects are

101 Here, we show that the lipolytic barrier of Plin5-enriched LDs, either prepared

102 Despite removal of lipolytic bursts, plasma FFAs (0.31 mM) and glycerol (0.

103 isolates showed amylolytic, cellulolytic and lipolytic, but not proteolytic activity.

104 This correlated with a decreased lipolytic capacity of GR-deficient adipocytes under post

105 hondrial energy use; lipid droplet assembly, lipolytic catabolism, and fatty acid compartmentalizatio

106 We demonstrate that ABHD5, a lipolytic co-activator, is ectopically expressed in CRC-

107 and ALBP constitute a functionally important lipolytic complex.

108 r LD fusion that is involved in a reversible lipolytic cycle in adipocytes.

109 ng or cardiac dysfunction than hearts with a lipolytic defect due to ATGL deficiency.

110 At the molecular level, the lipolytic defects in white fat were caused by impaired p

111 endothelial-bound lipolytic enzymes in human lipolytic deficiency states.

112 1A vesicles, suggesting that TgLCAT controls lipolytic degradation of Rab vesicles for cargo release.

113 rtmannin completely prevented insulin's anti-lipolytic effect but only minimally blocked [Ca2+]i's ef

114 iRNA dramatically attenuated the ISO-induced lipolytic effect in the cells.

115 This finding indicates that the anti-lipolytic effect of [Ca2+]i may be mediated by the activ

116 ide a historical and current overview of the lipolytic effect of GH in humans, mice and cultured cell

117 ated the mechanisms responsible for the anti-lipolytic effect of intracellular Ca2+ ([Ca2+]i) in huma

118 in adipose tissue from R6/2 mice, as was the lipolytic effect of isoproterenol.

119 We find that the lipolytic effect of leptin is mediated through the actio

120 Indeed, CST mimicked the lipolytic effect of the alpha-AR blocker phentolamine on

121 Zeng et al. reveal that the lipolytic effect of the hormone leptin is mediated by sy

122 perilipin (which has been implicated in the lipolytic effect of TNF-alpha) was not affected by gluco

123 ibition attenuated protein levels of the key lipolytic effectors hormone-sensitive lipase and adipose

124 ponectin levels increased sensitivity to the lipolytic effects of adrenergic receptor agonists.

125 We used microdialysis to study the in situ lipolytic effects of dobutamine (selective beta1-agonist

126 Glucocorticoid treatment mimicked the lipolytic effects of fasting, although with slower kinet

127 polysis was due to a suppression of the anti-lipolytic effects of insulin in adipocytes after chronic

128 irectionally similar to the androgen-induced lipolytic effects on visceral adiposity and equal in mag

129 pathetic neurons, which, in turn, attenuates lipolytic energy mobilization by adipocytes.

130 adipocytes causes redistribution of the key lipolytic enzyme ATGL to lipid droplets and increases li

131 esterase or bile salt-dependent lipase) is a lipolytic enzyme capable of hydrolyzing cholesteryl este

132 In particular, annotation of the lipolytic enzyme group (at least 110 members total) has

133 adipose triglyceride lipase (ATGL), the key lipolytic enzyme in the first step of TG breakdown.

134 In contrast, exposing LDL(-) to the key lipolytic enzyme lipoprotein lipase (LPL) reversed these

135 hibited via suppression of the extracellular lipolytic enzyme lipoprotein lipase.

136 sly uncharacterized pathway in which the key lipolytic enzyme LPL can act on circulating lipoproteins

137 However, a lipolytic enzyme Phospholipase D alpha1 (OsPLDalpha1) ca

138 oaches including genetic manipulation of the lipolytic enzyme Pnpla2, change in environmental tempera

139 lpha phospholipase A(2) (PLA(2)IValpha) is a lipolytic enzyme that catalyzes the hydrolysis of membra

140 Hepatic lipase is a lipolytic enzyme that has been suggested to have a role

141 rate successful expression and delivery of a lipolytic enzyme to the vascular endothelium for ultimat

142 indings reveal how cancer cells can co-opt a lipolytic enzyme to translate their lipogenic state into

143 Hepatic lipase (HL) is an endothelial-bound lipolytic enzyme which functions as a phospholipase as w

144 hat the promotor region of the rate-limiting lipolytic enzyme, adipose triglyceride lipase (ATGL), ha

145 A2 (PLA2), a small (13.8 kDa) Ca2+-dependent lipolytic enzyme, is rich in functional and structural c

146 d in mouse tears, where it may function as a lipolytic enzyme, modifying tear film lipids.

147 parvoviral virion gains entry by deploying a lipolytic enzyme, phospholipase A(2) (PLA(2)), that is e

148 riglyceride Lipase (ATGL), the rate-limiting lipolytic enzyme.

149 (eva) expression and decreased expression of lipolytic enzymes (hormone-sensitive lipase, lipoprotein

150 n and nitrogen cold plasma treatments on the lipolytic enzymes activity in wheat germ were investigat

151 d lipolysis with increased levels of the key lipolytic enzymes adipose triglyceride lipase (ATGL) and

152 nhanced via stimulation of the intracellular lipolytic enzymes adipose triglyceride lipase and hormon

153 These signals modulate the activity of lipolytic enzymes and accessory proteins, allowing for m

154 cell-surface glycosaminoglycan matrix where lipolytic enzymes and lipoprotein receptors reside.

155 P2 deficiency up-regulated the expression of lipolytic enzymes and protein kinase A signaling, result

156 isms of inhibition toward six representative lipolytic enzymes belonging to distinct lipase families

157 DSL/SGNH family II, and alipC clustered with lipolytic enzymes from family V.

158 eful in the replacement of endothelial-bound lipolytic enzymes in human lipolytic deficiency states.

159 nct physiological roles of these two similar lipolytic enzymes in lipoprotein metabolism.

160 to regulate the actions of gastrointestinal lipolytic enzymes in order to control the uptake of diet

161 Dietary triacylglycerol is acted upon by lipolytic enzymes in the stomach and the proximal small

162 particles, thereby indicating involvement of lipolytic enzymes in their generation.

163 The genome of Myxococcus xanthus encodes lipolytic enzymes in three different families: patatin l

164 Assaying lipolytic enzymes is extremely challenging because they

165 ation of lipidomics to developing assays for lipolytic enzymes revolutionizes in vitro testing for th

166 lipase A2 (PLA2) family of proteins includes lipolytic enzymes that liberate the sn-2 fatty acyl chai

167 The Green Recovery strategy utilizes lipolytic enzymes under the control of promoters induced

168 ted phosphatase, protease, or one of several lipolytic enzymes were not defective in vivo.

169 res the exquisitely regulated interaction of lipolytic enzymes with regulatory, accessory, and scaffo

170 cate that StnA represents a new subfamily of lipolytic enzymes with the specific binding pocket locat

171 bstantial similarity with the GDSL family of lipolytic enzymes, particularly the Moraxella bovis phos

172 action also triggers activation of bacterial lipolytic enzymes, the effects of nisin and PLA2 on the

173 lacrimal glands express mRNAs encoding other lipolytic enzymes, the present study was conducted to lo

174 AMP levels and downstream phosphorylation of lipolytic enzymes.

175 and distinct evolutionary origin from other lipolytic enzymes.

176 ze, and fat mass and increased expression of lipolytic enzymes.

177 characterization of interface specificity of lipolytic enzymes.

178 _4569 encodes a member of the GDSL family of lipolytic enzymes.

179 ce resonance energy transfer (FRET) assay of lipolytic enzymes.

180 mber of the GDSL (Gly-Asp-Ser-Leu) family of lipolytic enzymes.

181 This strategy may be applicable to other lipolytic enzymes.

182 ed by posttranslational modifications of key lipolytic enzymes.

183 Altogether, our results show that the lipolytic factor ABHD5 suppresses SRM-dependent spermidi

184 h ethanol causes acute pancreatitis (AP) and lipolytic fatty acid (FA) generation worsens AP, the con

185 In vitro, collagen I limited the lipolytic flux between acinar cells and adipocytes and p

186 ity of acute exacerbations of CP by reducing lipolytic flux between adipocytes and acinar cells.

187 220, that interacts with ATGL to inhibit its lipolytic function and promote triglyceride storage.

188 tests showed that Bhmt(-/-) mice had normal lipolytic function.

189 f lyophilized Hass avocado pulp powder shows lipolytic gastrointestinal enzymes led to appreciable bi

190 Our aim was to study the role of acute lipolytic generation of fatty acids on local severity an

191 ytica 5ST, and the characterization of three lipolytic genes and their translated protein.

192 Furthermore, augmented expression of FAO and lipolytic genes in FL-PGC-1alpha(-/-) white adipose tiss

193 pply might contribute to early expression of lipolytic genes in mouse hearts exposed to maternal obes

194 se in eWAT miR-1 abundance and expression of lipolytic genes.

195 elective beta2-agonist) on glycerol release (lipolytic index) in abdominal subcutaneous AT in 10 obes

196 hatidic acid acyltransferase activity in the lipolytic inhibitor G(0)/G(1) switch gene 2 (G0S2).

197 In addition to its role as a lipolytic inhibitor, G0S2 is capable of directly promoti

198 d profoundly hypothermic when treated with a lipolytic inhibitor.

199 ert, although how adipocytes integrate these lipolytic inputs is unknown.

200 aired lipid deposition coupled with impaired lipolytic lipid mobilization.

201 essing adipocytes promotes engagement of the lipolytic machinery and facilitates fatty acid oxidation

202 ve been made in describing the structure and lipolytic mechanism of human pancreatic triglyceride lip

203 igher triglyceride synthesis and a decreased lipolytic mechanism.

204 a-hydroxyacyl-CoA dehydrogenase, a marker of lipolytic metabolism; and lactate dehydrogenase, a marke

205 nate from plasma lipoproteins, show signs of lipolytic modifications, and associate with cholesterol

206 , LXRalpha) was increased, whereas that of a lipolytic nuclear factor PPARalpha was reduced in SH.

207 structure-activity studies of anticoagulant, lipolytic, or inflammatory activities.

208 selectively eliciting the therapeutic, anti-lipolytic pathway while avoiding the activation of the p

209 We sequenced 12 lipolytic-pathway genes in Old Order Amish participants

210 crobial activity, as well as proteolytic and lipolytic phenomena, decisive steps in such a ripening p

211 of phosphorylation on two components of the lipolytic process, the TG-lipase and the lipid droplet,

212 ulating their receptor-mediated clearance or lipolytic processing and the production of hepatic very

213 dothelial cell molecule that facilitates the lipolytic processing of chylomicrons has never been clea

214 protein 1 (GPIHBP1) plays a key role in the lipolytic processing of chylomicrons.

215 LPL carries out the lipolytic processing of triglyceride (TG)-rich lipoprote

216 Lipoprotein lipase (LPL) carries out the lipolytic processing of triglyceride-rich lipoproteins (

217 LPL, the enzyme responsible for the lipolytic processing of triglyceride-rich lipoproteins,

218 oprotein lipase (LPL) is responsible for the lipolytic processing of triglyceride-rich lipoproteins,

219 coprotein, binds LPL and is required for the lipolytic processing of triglyceride-rich lipoproteins.

220 lipase (LPL) avidly and is required for the lipolytic processing of triglyceride-rich lipoproteins.

221 l-anchored glycoprotein, and its role in the lipolytic processing of triglyceride-rich lipoproteins.

222 ggest that GPIHBP1 is a key platform for the lipolytic processing of triglyceride-rich lipoproteins.

223 teins (TRLs) along capillaries, allowing the lipolytic processing of TRLs to proceed.

224 e required neither HL binding to the LRP nor lipolytic processing.

225 ich lipoproteins along capillaries and their lipolytic processing.

226 to test the hypothesis that Pla2g1b and its lipolytic product lysophospholipid suppress hepatic fat

227 the T(2) of undigested lipids (~120 ms) and lipolytic products (0.1-15 ms).

228 Overall, the results indicate that lipolytic products can activate PPARalpha and PPARdelta

229 idative genes by elevating cAMP, but whether lipolytic products can modulate gene expression is not k

230 e that there is escape, or spillover, of the lipolytic products of LPL action on triglyceride-rich li

231 Little is known about the fate of the lipolytic products produced by the action of lipoprotein

232 e of both micronutrients and of triglyceride lipolytic products was found to be non-linear.

233 Adipocyte lipolytic products were altered by 5-PAHSA through selec

234 Equations were developed to quantify all the lipolytic products, and either referred to acyl groups p

235 ably caused by the accumulation of insoluble lipolytic products, appeared at the surface of the globu

236 carotene was found to follow the kinetics of lipolytic products, depending on the oil type (TC > HOSO

237 th regard to primary sequence, have distinct lipolytic properties (triglyceride lipase vs. phospholip

238 ly localized on lipid droplets and regulates lipolytic protein kinase A signaling by acting upstream

239 ecreased lipid droplet size, increased basal lipolytic rate and alterations in adiponectin and leptin

240 The addition of RSG reduced the lipolytic rate and TNF-alpha secretion.

241 d flow (ATBF) is an important determinant of lipolytic rate in vivo, we hypothesised that hypercortis

242 Further, the lipolytic rate increased by approximately 2- to 2.5-fold

243 nhanced the phosphorylation of Lsdp1 and the lipolytic rate of the lipase, demonstrating a prominent

244 In addition, lipolytic rate was assessed by glycerol release assay an

245 glucose production, suppress adipose tissue lipolytic rate, stimulate skeletal muscle glucose uptake

246 and protein level and a parallel increase in lipolytic rate.

247 n basal lipogenic rate and increase in basal lipolytic rate.

248 repression of Adrb3 expression and decrease lipolytic rate.

249 was significantly related to adipose tissue lipolytic rates and protein kinase A signaling in adipos

250 stingly, overexpression of ATGL restored the lipolytic rates in cells with silenced HSL or CGI-58, in

251 lterations in both adipose tissue (increased lipolytic rates) and hepatic (increased VLDL-TG secretio

252 of the lipid droplet, a critical step in the lipolytic reaction.

253 iglyceride-fatty acid cycling, regulation of lipolytic reactions, and glyceroneogenesis.

254 nces in the surface properties that regulate lipolytic reactivity are a predictable function of surfa

255 in POMC IR KO mice, consistent with impaired lipolytic regulation resulting in fatty liver.

256 al conceptual change in the understanding of lipolytic regulation.

257 PPARgamma is required for activation of the lipolytic regulatory network, dysregulation of which is

258 pase (MAGL) drives tumorigenesis through the lipolytic release and remodeling of free fatty acids.

259 lation of sympathetic inputs induces a local lipolytic response and depletion of white adipose mass.

260 A 10-h fast led to a similar lipolytic response as observed after active phase exerci

261 al sympathetic axis by which GDF15 elicits a lipolytic response in adipose tissue independently of an

262 This abnormal lipolytic response is exacerbated by a state of positive

263 Upon prolonged fasting, the impaired lipolytic response resulted in abnormal substrate utiliz

264 The decreased lipolytic response seen in the aP2-/- mice was not assoc

265 ng MRAP fat specifically exhibited increased lipolytic response to ACTH.

266 failed to augment the activation of PKA and lipolytic response to ACTH.

267 ference was associated with enhanced ex vivo lipolytic response to catecholamines and with greater le

268 C57BL/6 Pparg2-KO mice exhibited more active lipolytic response to catecholamines than 129S6/SvEv Ppa

269 that glucose metabolism is required for the lipolytic response to TNF-alpha but not for early signal

270 a PPARgamma-dependent regulatory node of the lipolytic response.

271 sible for the PKA-independent portion of the lipolytic response.

272 gion of perilipin abrogates the PKA-mediated lipolytic response.

273 ic women, 2) autonomic symptom awareness and lipolytic responses appear to be relatively increased in

274 oglycemia and ANS drive, lipid oxidation and lipolytic responses can be increased in type 1 diabetic

275 Analysis is done of pharmacological lipolytic responses combined with protein and mRNA expre

276 lly differentiated adipocytes have increased lipolytic responses to adrenergic stimuli.

277 lysis even in the presence of forskolin, and lipolytic responses were correlated with phosphorylation

278 cortisol, endogenous glucose production, and lipolytic responses were reduced by 40-80%.

279 isms of endogenous glucose production (EGP), lipolytic responses, and ketogenesis were also significa

280 Galphaq-deficient adipocytes display reduced lipolytic responses, shown to reflect a newly discovered

281 mice, BANKO mice had normal thermogenic and lipolytic responses.

282 hormone, endogenous glucose production, and lipolytic responses.

283 ion of ABHD5 is independent of its canonical lipolytic role.

284 Mass spectrometry analyses of the lipolytic secretome identified proteins involved in gluc

285 with long-standing obesity suggest a reduced lipolytic sensitivity to catecholamines in subcutaneous

286 Gpr3 transcription is cold-stimulated by a lipolytic signal, and dietary fat potentiates GPR3-depen

287 expression in human adipocytes increased the lipolytic signaling and suppressed the activity of trans

288 Regulation of lipolysis and lipolytic signaling by CD36 was reproduced with adipose

289 In conclusion, our study highlights a lipolytic signaling induced by Ces3 as a unique process

290 At the mechanistic level, lipolytic signals activate p53 in an adipose triglycerid

291 In sum, these data suggest that lipolytic signals, and cellular stressors such as DNA da

292 ially expressed in the NAS liver, suggesting lipolytic-specific regulatory effects by Notch1 signalin

293 but not brown, adipose tissue in response to lipolytic stimulation in a sirtuin-1 (SIRT1)-dependent m

294 Besides the secretion of fatty acids, lipolytic stimulation of adipocytes results in the secre

295 m to the nucleus following cAMP/PKA-mediated lipolytic stimulation.

296 ine secretion and sensitivity to insulin and lipolytic stimuli, recapitulating a healthier adipocyte

297 -type mice, but fail to respond maximally to lipolytic stimuli.

298 conditions and in response to starvation, a lipolytic stimulus.

299 nvestigate the separate contributions of the lipolytic versus ligand-binding function of hepatic lipa

300 delineate the separate contributions of the lipolytic versus ligand-binding function of HL to plasma