ライフサイエンスコーパス: lipophilic

1 tron-withdrawing but at the same time highly lipophilic.

2 mortality was significantly lower among both lipophilic (15.2% vs. 7.3%; RD, -7.9 percentage points [

3 ion enhancement (AIEE) effect in fluorescent lipophilic 2,1,3-benzothiadiazole (BTD) derivatives and

4 covalently modified by a non-bioreversible, lipophilic 4-alkylketobenzyl moiety.

5 arison, rats underpredicted the clearance of lipophilic acids, while overprediction was noted for hyd

6 (TFAB(-)) anion, which is also present as a lipophilic additive in the ion-selective membrane (ISM),

7 lyurethane films did not exhibit leaching of lipophilic additives after rinsing with a direct water j

8 sized trimethylammonium salts and reversible lipophilic aggregation of the host:guest complex provide

9 outine diagnostic measurements are devoid of lipophilic allergens such as oleosins.

10 sed size-selective precipitation to separate lipophilic allyl-benzyl-capped silicon nanoparticles int

11 m metabolism and the combination of fusing a lipophilic amine to a NOX inhibiting dye shows promise f

12 rgic targets and commonly described as small lipophilic amines.

13 f cyclocreatine or other chemically modified lipophilic analogs of Cr.

14 antigen rOspA from Borrelia burgdorferi, and lipophilic analogue norAbuMDP-Lys(B30) as adjuvant, are

15 Several less lipophilic analogues displayed improved aqueous solubili

16 a one-step procedure to a variety of chiral lipophilic and conformationally rigid amines and heteroc

17 various proteins, peptides and other larger lipophilic and hydrophilic moieties.

18 In this study, the lipophilic and hydrophilic phenol composition of virgin

19 in transforming native antiretrovirals into lipophilic and hydrophobic prodrugs stabilized into bioc

20 methyl group (CF(2) H) is considered to be a lipophilic and metabolically stable bioisostere of an am

21 We characterize the most relevant lipophilic and phenolic compounds of olives from Olea eu

22 The lipophilic and phenolic extractives of the ripe mesocarp

23 Cyt1Aa is lipophilic and synergizes Bti Cry proteins by increasing

24 Heme, itself a lipophilic and toxic molecule, presents a significant ch

25 nner between 2 common statins: atorvastatin (lipophilic) and pravastatin (hydrophilic).

26 mplexity are generally larger, slightly more lipophilic, and more polar.

27 vaginal administration of relatively potent, lipophilic, and small molecular weight drug molecules th

28 icating that the plasticizer, ionophore, and lipophilic anion are spontaneously distributed from the

29 e. SR without any plasticizer, ionophore, or lipophilic anion, was applied on top of a conventional p

30 the best selectivity for chloride over major lipophilic anions such as salicylate ( [Formula: see tex

31 fusion of leukocytes loaded ex vivo with the lipophilic antifungal posaconazole could improve deliver

32 At one go, lipophilic antimicrobials in Salvia miltiorrhiza root sa

33 e, total phenols, vitamin C, hydrophilic and lipophilic antioxidant activities respectively.

34 The bioactive compounds, hydrophilic and lipophilic antioxidant activity (HAA and LAA) in vitro,

35 The highest lipophilic antioxidant activity (LAA) was recorded in re

36 as well as between volatile terpenes and the lipophilic antioxidant activity, were observed in the gr

37 The lipophilic antioxidant N,N'-diphenyl-p-phenylenediamine

38 nd ascorbate concentrations, and hydrophilic/lipophilic antioxidant potentials by spectrophotometry,

39 the levels of coenzyme Q(10), an endogenous lipophilic antioxidant.

40 rfacial concentration decreased for the more lipophilic antioxidants.

41 armacophores bound to an affinity-generating lipophilic appendage, a polyethylene glycol-based linker

42 ially because of suspected interactions with lipophilic architectures, including membranes.

43 modified analogs of warfarin with additional lipophilic aromatic rings, up to 100-fold greater potenc

44 n and dynamic behavior were observed for the lipophilic aromatic rings.

45 ude a heteroaryl sulfonamide headgroup and a lipophilic aromatic tail group.

46 delivery of darunavir and potentially other lipophilic ARVs for treatment of HIV reservoir.

47 esters (0.5%w/v) with different hydrophilic-lipophilic balance (8; 11 or 16).

48 The incorporation of hydrophilic-lipophilic balance (HLB) adsorptive particles provided o

49 tracted thin film device using a hydrophilic lipophilic balance (HLB) coating, and an open bed config

50 icron thymol emulsions with high hydrophilic-lipophilic balance (HLB) surfactants via spontaneous emu

51 cteristics such as ionic nature, hydrophilic lipophilic balance (HLB) value, and critical micellar co

52 lecithin (5, 7, and 9% w/w) and Hydrophilic-Lipophilic Balance (HLB) values (6.76, 8.40, and 9.59).

53 s sites, a drone equipped with a hydrophilic-lipophilic balance (HLB), thin-film solid-phase microext

54 After hydrophilic-lipophilic balance cartridge purification, (68)Ga-HZ220

55 The meshes were coated with hydrophilic-lipophilic-balance particle-poly(acrylonitrile) (HLB-PAN

56 Uptake by DGT with HLB (hydrophilic-lipophilic-balanced) as the binding agent was relatively

57 T method in this study used HLB (hydrophilic-lipophilic-balanced) material as a binding agent, and me

58 By using lipophilic bases such as potassium 2-ethyl hexanoate, th

59 coefficient (1.91 +/- 0.24) showed a mainly lipophilic behavior.

60 ctive compounds into silicone oil, acting as lipophilic binder of glassy carbon paste electrode, with

61 c compounds to bind unpredictably within the lipophilic binding pocket.

62 tructures reveal a conical, rather large and lipophilic binding site and are the starting point for s

63 of oleogel system for efficient delivery of lipophilic bioactive components.

64 Nanoencapsulation of lipophilic bioactive compounds in food biopolymers is im

65 Encapsulation of lipophilic bioactive compounds using plant-derived prote

66 k evidences the potential of LNPs to protect lipophilic bioactive compounds with a high digestibility

67 ticles (SLNs) are emulsion-based carriers of lipophilic bioactive compounds.

68 ted as a functional food and as an excellent lipophilic bioactive molecule delivery vehicle in food f

69 ermint extracts rich in terpenoids and other lipophilic bioactives.

70 the generation of a precursor of a potential lipophilic bioisostere of gamma-aminobutyric acid (GABA)

71 hilicity, the CF(2)H group may act as a more lipophilic bioisostere of OH but as a similar or less li

72 c bioisostere of OH but as a similar or less lipophilic bioisostere of SH and CH(3), respectively, wh

73 ackground from nonspecific interactions with lipophilic cannabinoid ligand.

74 e-activity relationship study of a series of lipophilic carbonic anhydrase (CA) inhibitors with an ac

75 nine lipids (ICLs, DiR, DiD, DiI) as a model lipophilic cargo, via different carriers.

76 noid-binding protein (IRBP) is a specialized lipophilic carrier that binds the all-trans and 11-cis i

77 omputed tomography (SPECT) imaging, but as a lipophilic cation its distribution is also governed by m

78 Lipophilic cation PET tracers may be suitable for early

79 lly to mitochondria is by covalent linking a lipophilic cation such as an alkyltriphenylphosphonium m

80 ochondria is by covalently linking them to a lipophilic cation, the in vivo delivery of free drugs st

81 ent, comparing it with leading PET and SPECT lipophilic cationic tracers before further assessing its

82 Due to the lipophilic cationicity and primary amine docking group,

83 Here, we show that mono-alkyl lipophilic cations (MALCs) inhibit oxidative phosphoryla

84 s is the first demonstration of radiolabeled lipophilic cations being used for the PET imaging of che

85 Other delocalized lipophilic cations, such as rhodamine, natural and synth

86 ical basis for mitochondrial accumulation of lipophilic cations, synthetic chemistry strategies to ta

87 vel drug-binding sites outside the conserved lipophilic central cavity and to identify new allosteric

88 organelle pH, and changing the nature of the lipophilic chain provokes a loss of selectivity.

89 The DCF affinity appears to depend on the lipophilic character of organoclays in correlation to th

90 The lipophilic character of the dyes enabled their applicati

91 herently bioincompatible due to their highly lipophilic character.

92 ties due to the electron-withdrawing, albeit lipophilic, character of the SCF(3) group, which can be

93 biphenyls (PCBs) are toxic, persistent, and lipophilic chemical compounds that accumulate to high le

94 dimethylchroman-6-ol (CR-6) with that of the lipophilic cholinesterase inhibitor 6-chlorotacrine resu

95 to an archlike structure that covers a deep lipophilic cleft.

96 Lipophilic CO2 extracts were rich in tocopherols (2.36-1

97 antibacterial activity (a nitrogenous and a lipophilic component).

98 irculatory disturbance-related diseases; its lipophilic components play important roles in this appli

99 The predominant lipophilic compounds are kaurene diterpenes (42.2-59.6%)

100 The encapsulation of bioactive lipophilic compounds by complex coacervates of gelatin A

101 concurrent extraction and solubilisation of lipophilic compounds might be of a great interest.

102 Carotenoids are lipophilic compounds that are digested and absorbed alon

103 The antioxidant capacity of 9 pure lipophilic compounds was examined by microplate-ABTS and

104 an maceration whereas the highest amounts of lipophilic compounds were detected in macerates.

105 INS similarities, and ADMET risks typical of lipophilic compounds.

106 e desorption process becomes unimportant for lipophilic compounds.

107 and composition in terms of hydrophilic and lipophilic compounds.

108 a promising encapsulant for the delivery of lipophilic compounds.

109 cofactor to relatively low-molecular weight lipophilic compounds.

110 the bioaccessibility and bioavailability of lipophilic compounds.

111 ydrates, whereas dSPE removed fats and other lipophilic compounds.

112 ve fluorophore, showing high fluorescence in lipophilic conditions.

113 phisticated interaction pattern of polar and lipophilic contacts that were used to improve cellular p

114 form micelles due to its limited hydrophilic/lipophilic contrast.

115 However, the lipophilic core of the most commonly used structure (Fin

116 orption fluorescent small bioprobes based on lipophilic coumarin were developed, which exhibited high

117 We then used lipophilic Cy-7 exendin to selectively preblock exocrine

118 upramolecular sensors for creatinine and its lipophilic derivative hexylcreatinine.

119 eased the antioxidant efficiency of the more lipophilic derivatives.

120 in-B (a cytolytic peptide), valproic acid (a lipophilic drug), and amyloid-beta (a peptide associated

121 ation is routinely used for oral delivery of lipophilic drugs in vivo, with the emulsion forming in v

122 Lipophilic drugs, such as taxanes, have a high affinity

123 salts interact, increasing the absorption of lipophilic drugs, their bioaccessibility predictions mus

124 sity lipoprotein (VLDL), the main carrier of lipophilic drugs.

125 luenza virus were labeled with a fluorescent lipophilic dye (DiD).

126 postmortem human brains, immersion fixation, lipophilic dye (DiI) labeling, and confocal microscopy.

127 Rather, labelling with the lipophilic dye DiI shows that late-migrating cells, orig

128 We combined loading of the lipophilic dye FM1-43 with photoconversion, electron mic

129 As opposed to lipophilic dye molecules, no significant shift in the si

130 a, gfap or s100 Rather, lineage tracing with lipophilic dye or inducible Sox10-Cre suggests that post

131 as cell body position, axon projections and lipophilic dye uptake, we have assigned homologies betwe

132 erves emission from fluorescent proteins and lipophilic dyes in membrane integrity preserved tissues.

133 n improved clearing protocol compatible with lipophilic dyes that highlight the neurovascular network

134 lactam-containing EZH2 inhibitors focused on lipophilic efficiency (LipE) improvement, which provided

135 dentified compound 1 as a hit with promising lipophilic efficiency (LipE).

136 This compound displays a 5-unit increase in lipophilic efficiency from the fragment hit, excellent k

137 ntration needed to double receptor response, lipophilic efficiency, and aqueous solubility, and lower

138 lly efficacious inhibitor of SHP2, with high lipophilic efficiency, improved potency, and enhanced ph

139 pt cellular function; these include a highly lipophilic element that promotes strong membrane interac

140 eins for T cell activation is susceptible to lipophilic environmental pollutants.

141 e to its unrivaled fluorescent properties in lipophilic environments.

142 In this work, we proposed a novel lipophilic ester prodrug approach, combined with oral li

143 a antarctica lipase B-catalysed synthesis of lipophilic esters of polydatin was investigated along wi

144 proton NMR spectroscopy were used to analyse lipophilic extracts from ground roast coffees.

145 The application of both methods to real lipophilic extracts from tomato (Solanum lycopersicum L.

146 e not systematically observed in the natural lipophilic extracts from tomato, green and red peppers,

147 ied for non-selective recovery of peppermint lipophilic extracts.

148 By identifying a bright, lipophilic fluorescence turn-on probe that enables susta

149 Lipophilic fluorescent dye molecules such as the PKH fam

150 With rotationally confined lipophilic fluorophores and the polarized incident fluor

151 at optimised parameters yielded 8.3g/100g of lipophilic fraction containing 0.2 and 2.2g of cannabidi

152 ction, useful spectra were obtained from the lipophilic fraction of ground roast coffees.

153 Oil of lipophilic fraction was composed mainly of healthy polyu

154 optimized parameters yielded 11.8 g/100 g of lipophilic fraction, containing 43.3 and 37.4% of alpha-

155 during stimulation of BAT thermogenesis, the lipophilic gas xenon preferentially accumulates in BAT,

156 hydrophobicity and substitution geometry of lipophilic groups play important roles in compound-lipid

157 Conjugation of siRNAs to lipophilic groups supports efficient cellular uptake by

158 Recently, conjugation of lipophilic groups to AGs generated a novel class of pote

159 Lipophilic (>300mgkg(-1)) and hydrophilic phenols (>600m

160 We also introduced less lipophilic head heterocycles devoid of covalent binding

161 Here, we introduce IR-780 iodide, a lipophilic heptamethine dye with a peak optical absorpti

162 eplacing the terminal phenyl group with less lipophilic heterocycles, or (iii) generating extended bi

163 Although most targets favored lipophilic hits, the average clogP of hits at a given ta

164 tem and highlight the critical importance of lipophilic hotspots and water molecules for these peptid

165 The unique combination of a lipophilic hydrocarbon tail with a modified polyphenolic

166 difluoromethyl group, as it is considered a lipophilic hydrogen bond donor that may act as a bioisos

167 Lipophilic indicator dyes were incorporated into core-sh

168 hinone IIA (TSA) are the most widely-studied lipophilic ingredients, but low oral bioavailability lim

169 NLCs carrying lipophilic IR780 were also released from the aqueous cha

170 (-) (BArf =B(3,5-C6 H3 (CF3 )2 )4 ) to give lipophilic Lambda- and Delta-3 a-d(3+) 3 BArf (-) , whic

171 w a biophysical scheme based on the use of a lipophilic Laurdan dye for examining MIN6 cell membranes

172 LTC4S inhibitor (IC(50) = 0.28 nM) with high lipophilic ligand efficiency (LLE = 8.5), which displays

173 ulted in a series of compounds with improved lipophilic ligand efficiency (LLE) consistent with the r

174 Optimization of cellular lipophilic ligand efficiency (LLE) in a series of 2-anil

175 erties and a pIC(50) hWB(free) of 8.1 and an lipophilic ligand efficiency of 5.2.

176 ith submicromolar IC(50) values and improved lipophilic ligand efficiency.

177 ceptors (NRs) regulate physiology by sensing lipophilic ligands and adapting cellular transcription a

178 and potential with respect to two different lipophilic ligands.

179 ng low-density lipoprotein (LDL), while less lipophilic lipid-siRNAs bind to high-density lipoprotein

180 i pyramids; assembly is driven by the facile lipophilic-lipophilic association of the alkyl moieties

181 ereas adult skin is predominantly obligatory lipophilic Malassezia, suggesting that fungal communitie

182 acts suggested acrylamide not to bind to any lipophilic material.

183 ants for application in both hydrophilic and lipophilic media.

184 nderstanding the function of nitric oxide, a lipophilic messenger in physiological processes across n

185 and prolong mammary tissue persistence of a lipophilic metal complex of CPX and Zinc (CPXZn) after i

186 thod for the preparation of cell-penetrating lipophilic metallocorrole/serum-protein nanoparticles (N

187 of the molecule were designed to occupy the lipophilic methionine side chain recognition pocket as w

188 Notably, transport-independent lipophilic methyl-conjugates of pyruvate and tricarboxyl

189 The kinetics of micellar solubilization of lipophilic micronutrients (bioaccessibility) in relation

190 f triglyceride droplets containing different lipophilic micronutrients.

191 onucleotide (ASO) with a variety of distinct lipophilic moieties like fatty acids and cholesterol inc

192 vivo We show here that peptides tagged with lipophilic moieties self-assemble into nanoparticles unt

193 y recognition motif, which is connected to a lipophilic moiety occupying an extended binding pocket (

194 Connection of a lipophilic moiety to the arylpiperazine core by an appro

195 o referred to as coenzyme Q, is a widespread lipophilic molecule in both prokaryotes and eukaryotes i

196 FDA-approved arsenic trioxide, with the most lipophilic molecule in the series showing the best growt

197 ating example of how partitioning of a small lipophilic molecule into a phase-separated cellular cons

198 Compound 1 is a dibasic lipophilic molecule that is predicted to accumulate in l

199 CoQ10 is a highly lipophilic molecule with a chemical structure similar to

200 um sativum protein hydrolysate (LSPH) with a lipophilic molecule, curcumin (CUR), and its effect on c

201 Removal of GML and other lipophilic molecules from human milk by ethanol extracti

202 , which is critical for excluding many small lipophilic molecules from the brain parenchyma.

203 tional studies, suggest that amphiphilic and lipophilic molecules may gain access to these receptors

204 equestration from the interaction with other lipophilic molecules of the oleoresin.

205 oven successful for administration of small, lipophilic molecules such as sex steroids.

206 tive of the rate-determining mechanism, with lipophilic molecules tending toward metabolism and hydro

207 , EAAT2b), while others are quite penetrant (lipophilic molecules, Cx30, ZO-1, Occludin).

208 e a wide variety of endogenous and exogenous lipophilic molecules, including most drugs.

209 cationic amphiphilic motif represented by a lipophilic n-octyl side chain at position 1 and a positi

210 tionship of these compounds, we suggest that lipophilic N6 and bulky C2 substituents can promote stab

211 steroid-binding sites also occupied by other lipophilic nAChR antagonists.

212 n initial series of studies, three different lipophilic nalmefene derivatives were evaluated: the pal

213 In the case of lipophilic nanoparticles, which are widely used in consu

214 The lipophilic nature of cannabinoids necessitates mechanism

215 g high extraction yield (up to 72%) for most lipophilic neuropeptides.

216 nly been derived based on empirical data for lipophilic neutral compounds and may not predict the upt

217 rformance due to their propensity to adopt a lipophilic, nonfluorescent form.

218 food systems, particularly those containing lipophilic nutrients.

219 ation of the ethylhexyl chain, yielding very lipophilic OC analogues that accumulate in coral tissues

220 The increasingly lipophilic octanoate (C8), decanoate (C10) and dodecanoa

221 a cation exchanger) and chromoionophore I (a lipophilic optical pH indicator) are printed on filter p

222 ed structure of the lipid bilayer may direct lipophilic or amphiphilic drugs to a specific depth with

223 ets that have large, featureless, and highly lipophilic or highly polar and/or flexible binding sites

224 ctive optodes and with pH optodes containing lipophilic organic electrolyte.

225 ification means the liberation of persistent lipophilic organic pollutants (PLOPs) into blood from th

226 lation influences skin permeability and that lipophilic particles smaller than 6 nm can embed in lipi

227 hniques aimed at identifying hydrophilic and lipophilic pathways of permeation.

228 ound only in honey samples, whereas the more lipophilic pesticides were predominantly found in beeswa

229 The anion ionophore and a lipophilic pH indicator are inkjet-printed and adsorbed

230 reated milk, but little has been studied for lipophilic phenolic compounds that are to be encapsulate

231 his study aimed to evaluate an (18)F-labeled lipophilic phosphonium cation, [1-(2-(18)F-fluoroethyl),

232 Carotenoids are lipophilic phytochemicals; their intake has been associa

233 producing durum wheat pasta enriched with a lipophilic phytocomplex, extracted using supercritical c

234 The physical-chemical properties of the new lipophilic pigment were studied by UV-vis spectroscopy.

235 Carotenoids refer to a wide class of lipophilic pigments synthesized by plants, exert photopr

236 r conformations and interactions: filling of lipophilic pockets to gain affinity or selectivity, addi

237 his notion, we determined whether the common lipophilic pollutants benzo[a]pyrene and diesel exhaust

238 Females transfer lipophilic pollutants more easily to eggs, and to a high

239 tation for T cell activation is inhibited by lipophilic pollutants through profound interference with

240 suggesting migration has a greater effect on lipophilic pollutants.

241 e dominant reservoir for the accumulation of lipophilic pollutants.

242 Lipophilic polychlorinated biphenyls (PCBs) accumulate w

243 igration strategy on pollutant occurrence of lipophilic polychlorinated biphenyls (PCBs) and protein-

244 ansfer of anthropogenic pollutants including lipophilic polychlorinated biphenyls (PCBs) and protein-

245 Suberin, a lipophilic polymer deposited in the outer integument of

246 A lipophilic polysiloxane membrane is selectively permeabl

247 mics simulations, binding of ivabradine to a lipophilic pore access site is coupled to a state-depend

248 ionalized with sulfonic acid moieties in the lipophilic portion assemble in water and locate the Bron

249 rp-453 (M4), a residue photolabeled by small lipophilic probes and promegestone, a steroid nAChR anta

250 on spectra (3D orientation plus "wobble") of lipophilic probes transiently bound to lipid membranes,

251 However, a combination of the lipophilic prodrug approach with lipid-based formulation

252 Here we describe RCB-185, a lipophilic prodrug with nanomolar activity against asexu

253 s were converted into bioreversibly modified lipophilic prodrugs at the gamma-phosphonate by the atta

254 oducing a hydrophilic group to interrupt the lipophilic, promiscuous pharmacophore and promote intera

255 and b) masking of the peptide charge with a lipophilic protecting group.

256 ed binding through extensive contacts with a lipophilic protein patch.

257 Highly lipophilic, pyrethroids accumulate in sediments and bioa

258 ilic antibiotic tobramycin (Tob) and a novel lipophilic QSI at 30 % and circa 10 %, respectively.

259 Catalysis of both NADH oxidation and lipophilic quinone reduction by membrane-bound NDH-2 fol

260 del system when oxidation was initiated by a lipophilic radical initiator (2,2'-azobis(2,4-dimethylva

261 lso known as ubiquinone-10), which acts as a lipophilic radical-trapping antioxidant that halts the p

262 Only less lipophilic radiometabolites appeared in plasma.

263 enhanced suitability for incorporation into lipophilic regions of liposomes and subsequent in vitro

264 ruct is an artificial four-helix bundle with lipophilic regions that are defined only by the amino ac

265 boron-dipyrromethene (BODIPY) fluorophore (a lipophilic reporter segment).

266 3,3'-Diindolylmethanes bearing small lipophilic residues at the 5- and/or 7-position of the i

267 Small polar or lipophilic residues increased potency, 2-iodo- and 2-chl

268 The last two lipophilic residues of tetraspanin 33, Trp-283 and Tyr-2

269 cy and JAK1 selectivity: Optimization of the lipophilic ribose pocket-targeting substituent was follo

270 In a typical experiment, custom lipophilic RNTPs were first inserted into lipid vesicles

271 The impact of these highly lipophilic sensors has, however, been limited due to the

272 s for enhancing the extrahepatic delivery of lipophilic siRNAs.

273 We formulated Ro5-3335, a lipophilic small molecule RUNX1 inhibitor, into a nanoem

274 We achieve the necessary lipophilic solubility switch of the protein material by

275 1 years; LDL = 102 +/- 2 mg/dl) treated with lipophilic statin (10-40 mg daily).

276 10-year HCC risk was lowest with 600 or more lipophilic statin cDDDs (8.4% vs. 2.5%; RD, -5.9 percent

277 ther research is needed to determine whether lipophilic statin therapy is feasible for prevention of

278 -year HCC risk was significantly lower among lipophilic statin users (8.1% vs. 3.3%; absolute risk di

279 The inverse association between lipophilic statins and HCC risk seemed to be dose-depend

280 Lipophilic statins prevent membrane association and acti

281 (OR 0.84; 95%CI: 0.70-1.01, p = 0.060), but lipophilic statins were associated with a CRC risk reduc

282 In a nationwide viral hepatitis cohort, lipophilic statins were associated with significantly re

283 dextrin (BCD) is a compound that solubilizes lipophilic substances.

284 The compound with a bulky lipophilic substituent (SnBu(3)) exhibits a relatively h

285 to beta (+), while derivatives with bulkier lipophilic substitutions [4-(tert-butyl)-propofol and 4-

286 ide cues for membrane identity by exchanging lipophilic substrates, ultimately governing membrane sig

287 forces do not differ between hydrophilic and lipophilic surfaces, ranging between 58 and 186 mN, and

288 organic solvent through the synthesis of new lipophilic tert-butyl ketone precursors.

289 of apoAI with that of apoAII, which is more lipophilic than apoAI, using HDL-[(3)H]CE labeled with [

290 se, thus suggesting greater effectiveness of lipophilic than hydrophilic/phenolic antioxidants under

291 (73-83%), and distributed preferentially to lipophilic tissues.

292 Among lipophilic tocochromanols gamma-tocopherol was the most

293 W) pastas, enriched respectively with either lipophilic (tocochromanols, carotenoids) or hydrophilic/

294 f hydrophilic (sugars and organic acids) and lipophilic (tocopherols and PUFA) compounds.

295 ondrial H2S levels in vivo MitoA comprises a lipophilic triphenylphosphonium (TPP) cation coupled to

296 owed overcoming solubility problems with the lipophilic vanillin and cinnamaldehyde and neutralizing

297 A lipophilic version of the tetralactam macrocycle was pre

298 ecreasing acidity of substrates entering the lipophilic vestibules and protonation via the bulk water

299 pherol known as the most active form of this lipophilic vitamin.

300 ated fatty acids, sterols, coenzyme Q10, and lipophilic vitamins, such as vitamins D(3) and A.