ライフサイエンスコーパス: live

1 hysical nature of the habitats in which they live.

2 tions before the individuals who we analysed lived.

3 ents from their families at the end of their lives.

4 ized by worry and vulnerability lived longer lives.

5 3 levels in oysters relative to conventional live algal diets.

6 Here we use live and fixed cell imaging to uncover the role of Nek84

7 Using live and fixed fluorescence imaging and electrophysiolog

8 mmon Era), and it resulted in the loss of 59 lives and $25 billion in damages across the southeastern

9 e universal, and we study them comparing the living and non-living two-dimensional systems self-organ

10 of animals involved-hundreds of millions of live animals are imported into the U.S.A. alone every ye

11 pecific targeting methods in brain tissue or living animals.

12 V-1 vaccination requires elicitation of long-lived antibody responses.

13 BACKGROUNDThe live attenuated BPZE1 vaccine candidate induces protecti

14 This strategy may be useful for generating live attenuated vaccine candidates that prevent disease

15 may be a novel target for rational design of live attenuated vaccines and antiviral drugs.

16 r antiviral discovery and development of new live attenuated vaccines.

17 nactivated, Vero-cell derived, JENVAC to the live-attenuated SA 14-14-2 vaccine in healthy children.

18 To control TMUV infection, a live-attenuated vaccine candidate of TMUV was developed

19 f TCRV and to explore its potential use as a live-attenuated vaccine or a vaccine vector for the trea

20 ammarenaviruses, for their implementation as live-attenuated vaccines or vaccine vectors.IMPORTANCE T

21 Mtb- specific antigens and live bacillus Calmette-Guerin (BCG) were used as stimuli

22 control over the disease and revert societal live back to normal.

23 lla infection in germ-free mice to show that live bacterial virulence factor-driven immunogenicity ca

24 by using their elaborately armored heads as living barricades.

25 igh proportions of Latino/a residents, those living below the federal poverty line and with high hous

26 analyses, participants who were black, were living below the poverty level, and had low health liter

27 we report the novel concept of a microalgae living biosensor by enhancing photocurrent through nanoc

28 fy the scope of influenza viruses present in live bird markets and the threat they pose to human heal

29 ridged-race, intercensal population data and live birth estimates were used as denominators.

30 up to 10% of childhood blindness (~1 in 5000 live birth).

31 and supported fetal development to term and live birth.

32 based cohort study of all recorded singleton live births from January 1, 1996 to December 31, 2015 us

33 This study included 3422 and 3508 singleton live births from the Australian Longitudinal Study on Wo

34 gression models were used to jointly analyse live body weight measured in different time points throu

35 Live C. trachomatis recovered from vaginal swabs or endo

36 ed the subcellular enrichment of glycogen in live cancer cells and achieved specific glycogen mapping

37 d supply chain of Brazilian meat, offal, and live cattle exports from 2015 to 2017, a trade worth mor

38 It stimulated effector generation, long-lived CD4 memory generation, and robust generation of Ab

39 Live cell imaging allows direct observation and monitori

40 Here, using multiphoton live cell imaging in mouse kidney tissue, FIB-SEM, and o

41 This strategy enables us to obtain real-time live cell imaging of redox states in TfR1-mediated endoc

42 and activates a conditional fluorophore for live cell imaging of RNA.

43 roach combines serial affinity purification, live cell imaging, and cross-linking mass spectrometry t

44 Live cell microscopy using chemical and genetic reporter

45 ells were plated either onto well plates for live cell, fluorescent reactive oxidative species (ROS)

46 In live cell-based assays, LGI1 epitope recognition was exa

47 ng cAMP, stimulated the degradation of short-lived cell proteins, but unlike cAMP, also markedly incr

48 fully comprehensive computational model of a living cell may be drawing closer to reality, but our an

49 es to lipids and E-cadherin molecules at the living cell surface.

50 vironment of a giant vesicle, derived from a living cell.

51 ly complex nanostructures has revolutionized live-cell analysis.

52 To perform live-cell dynamic tension imaging, we engineered reversi

53 ast to the minimal phototoxicity required in live-cell experiments.

54 Live-cell imaging after individual ASD-gene repression v

55 Live-cell imaging and microscopy were used to determine

56 ection of TNF cleavage in flow cytometry and live-cell imaging applications.

57 Live-cell imaging coupled with targeted gene knockouts a

58 that such processes can explain experimental live-cell imaging data measuring distances between regul

59 ion of theoretical modeling and quantitative live-cell imaging experiments, we show that local deplet

60 Here, by using immunohistochemistry and live-cell imaging of specific mRNAs, we describe for the

61 Moreover, live-cell imaging studies examining Vif-mediated degrada

62 0) employ unbiased proteomics approaches and live-cell imaging to reveal a key role for the histone c

63 Thus, we introduce a live-cell imaging tool to facilitate in vivo studies of

64 In this study, live-cell measurement of RhoA activation revealed a biph

65 , using high spatial and temporal resolution live-cell microscopy, we identified a role for mitochond

66 We introduce a live-cell points accumulation for imaging in nanoscale t

67 d single-molecule localization microscopy on live-cell samples.

68 Here, we use live-cell single-molecule imaging in human cells to dete

69 ture of our binder as tyrosination sensor, a live-cell tubulin nanobody specific towards tyrosinated

70 m of F-actin-driven NE rupture by correlated live-cell, super-resolution and electron microscopy.

71 e tested for AQP4-IgG and MOG-IgG by using a live-cell-based flow cytometry assay.

72 eserve potent and specific NCEH1 labeling in live cells and animals, while permitting facile (18) F r

73 cyclopamine on the SMO transmembrane core in live cells in real time.

74 ne via dual fluorescent reporters in single, live cells of the yeast Saccharomyces cerevisiae.

75 expands the types of manipulation in single live cells to address cell biology questions otherwise i

76 might help in detecting local DNA damage in live cells, as well as in aiding our biophysical underst

77 king on a range of GFP proteins expressed in live cells, neurons, and small organisms.

78 uantify Wnt-FZD interactions in real time in live cells, utilizing a recently established NanoBRET-ba

79 ble of monitoring in-situ activity of LAP in live cells.

80 tors without requiring barcode expression in live cells.

81 formation to measure the lipid metabolism of live cells.

82 ly described a method to introduce DELs into living cells and recover conjugates that bind to an intr

83 conditions, and find that regions containing living cells are maintained at cooler temperatures.

84 ssing conformational changes in receptors in living cells at ambient conditions.

85 in payload delivery to between 75 and 97% of living cells of three species: B. dendrobatidis, B. sala

86 Synthetic assembly within living cells represents an innovative way to explore pur

87 or the spontaneous formation of OR dimers in living cells under physiological conditions is missing.

88 nano-electronic interface to the interior of living cells with integrated fluorescence readout of met

89 er, approaches that allow us to probe G4s in living cells without perturbing their folding dynamics a

90 struction of organelle-like architectures in living cells, but has proven difficult due to the lack o

91 oncentration remains largely untested within living cells, in which the richly multicomponent nature

92 It has not been possible, in living cells, to precisely characterize the respective c

93 have been studied by tracking viruses within living cells, which limits the precision with which fusi

94 nt turn-on probe for labeling sphingosine in living cells.

95 ation from individual HIV-1 RNA molecules in living cells.

96 hanical properties of isolated nuclei and in living cells.

97 eras and example oligomeric complexes inside living cells.

98 ul means to quantify biochemical dynamics in living cells.

99 ve mice with RSV-infected BMDCs exacerbate a live challenge with RSV infection but was inhibited when

100 ical properties with a high fraction of long-lived charge carriers and the availability of a reductiv

101 ween incidence of diabetes mellitus (DM) and living conditions has not been studied after natural dis

102 h the temporal regulation of initiation in a living coordination-insertion polymerization of ethylene

103 a critical functional group, independent of live coral loss.

104 Although live coral tends not to face directly into the prevailin

105 city of melatonin was carried out using both live/dead and MTT assays.

106 Cellular viability was assessed using LIVE/DEAD stain kit and the recellularised scaffolds wer

107 zation rates, time to inpatient mortality or live discharge, and 30-day readmission risk using bivari

108 t appear to be related to network size or to living donation requests, but rather to the network memb

109 ously observed racial and sex disparities in living donor kidney transplantation do not appear to be

110 Patients were grouped as having received a living donor liver allograft from either an offspring or

111 T for ALD using data from the adult-to-adult living donor liver transplantation (A2ALL) study, which

112 We studied outcomes following living donor liver transplantation (LDLT) post-PVTT down

113 tlist registrations, waitlist mortality, and living-donor and deceased-donor kidney transplants (LDKT

114 -donor kidney transplant alone (DD-KA, 68%), living-donor kidney transplant alone (LD-KA, 30%), or SP

115 Eighteen recipients received uteri from living donors and 2 from deceased donors.

116 Outcome metrics for living donors include patient survival, survival free of

117 stry (NKR) Advanced Donation Program enables living donors the opportunity to donate altruistically,

118 dney transplant recipients and 2 transgender living donors was constructed and analyzed.

119 nor islets required from either cadaveric or living donors.

120 wledge gap, we investigated dissipation half-lives (DT50s) of 31 substances (mainly pharmaceuticals)

121 antitatively characterize gene repression in living E. coli by a collection of individual TALED loops

122 n of the electron gas, and periodic and long-lived electron cyclotron oscillations inside the magneti

123 hat quantify mobility in unsupervised, daily living environments are emerging as complementary clinic

124 he mobility of transition metal catalysts in living environs.

125 they transmit claim at least a million human lives every year globally.

126 ory calculations, first insights into a long-lived excitonic state are gained and discussed.

127 specific to harmful intent attributions, the live expression of paranoia.

128 dopamine and acetylcholine co-stimulation in living flies.

129 Trees are the living foundations on which most terrestrial biodiversit

130 its and the demographic competence of faster-living hosts also has implications for trade-offs betwee

131 aracteristics of retinal macrophage cells in live human eyes, both healthy and diseased, with the uni

132 tless males also gain strong attraction to a live human host, a behavior that wild-type males never d

133 NT probes to map integrin receptor forces in live human platelets and mouse embryonic fibroblasts.

134 However, there are little data on living human microglia, especially in diseased states.

135 Using live imaging and computational approaches, we found that

136 New biosensors and live imaging in zebrafish revealed that neutrophil chemo

137 Co-expression and live imaging studies indicate that the expansion does no

138 A perspective on the future use of live imaging technologies and overcoming their current l

139 models are a powerful system for discovery, live imaging, and functional investigation of cell state

140 tential targets for meningioma therapy using live imaging, single cell RNA sequencing, CRISPR interfe

141 Using live imaging, we show that the somitogenesis clock is ac

142 ve bone resorption, which can be assessed by live imaging.

143 likely to practice social distancing if they live in a media market that is more impacted by COVID-19

144 Primates live in complex social systems with social structures ra

145 Millions of the world's poorest people now live in middle-income democracies that, in theory, could

146 periods of exposure, and animals adapted to live in these environments are predicted to deal more ef

147 Approximately 569 million people live in those areas with deceasing SWA or TWS trends in

148 eir wild ancestor, the Red junglefowl, which lives in humid and sub-humid tropical areas.

149 s could negatively impact 1.9 billion people living in (0.3 billion) or directly downstream of (1.6 b

150 We enrolled 1242 of 1397 adults (89%) living in 533 households (median age 41 years; 43% male)

151 There was a positive association between living in a hard water (range: 76 to > 350 mg/L CaCO(3)

152 ), HIV positivity (OR = 2.22(1.32-3.73)) and living in a more rural area (OR = 1.38(1.01-1.89)) are s

153 a large proportion of the world's population living in areas where air quality does not meet current

154 icrobiome is an assemblage of microorganisms living in association with a multicellular host.

155 ospective study of premenopausal Black women living in Detroit who underwent serial ultrasound.

156 0.3, 1.2; p = 0.001) compared with those not living in drought.

157 Women living in mild/moderate drought had higher risk of repor

158 Children living in neighbourhoods surrounded by high levels of SR

159 H)D concentrations were lower in populations living in northern African countries or South Africa com

160 s living in temporary housing (TH) and those living in other types of accommodation (non-TH) five yea

161 ownturn in the global economy, the impact of living in quarters among families who are the most at ri

162 ared the incidence of DM between individuals living in temporary housing (TH) and those living in oth

163 ce genes to other bacteria, e.g. to the ones living in the human gut.

164 yellow-bellied marmots (Marmota flaviventer) living in two different elevational environments to quan

165 Living in various habitats, tardigrades play major roles

166 Test positivity was greater for persons living in zip codes with lower annual household income.

167 higher on general neuroticism lived shorter lives, individuals whose neuroticism was characterized b

168 d, including the lifespans of short and long-lived infected cells, and the time to reach viral suppre

169 to screen for microcrystal formation within living insect cells.

170 3+) charge state have been proposed as short-lived intermediates in a number of enzymatic reactions.

171 Long-term safety of living kidney donation (LKD), especially for young donor

172 essment is a key aspect in the evaluation of living kidney donor candidates; however, data on perform

173 ing techniques, and two-photon microscopy in living knock-ins enables the visualization of tissue rej

174 Yeast and other organisms live longer when they lack specific ribosomal proteins,

175 was characterized by worry and vulnerability lived longer lives.

176 st time, the videos of labeled EVs uptake by living lung cancer cells.

177 n in three settings: in vitro wound healing, live lymph node sections and a live tumor microenvironme

178 , it was possible to follow the migration of live M. bovis Bacille Calmette-Guerin (BCG) and to obser

179 are independent of protein expression within live macrophage cells.

180 ection of endogenous carbon monoxide (CO) in live mammalian cells under normoxic and hypoxic conditio

181 ycans at the single-virion level directly on living mammalian cells, which offers new perspectives to

182 ed evolutionary constraint in large and long-lived mammals.

183 The tuatara (Sphenodon punctatus)-the only living member of the reptilian order Rhynchocephalia (Sp

184 o stiffness seen in extant great apes (i.e., living members of the Hominidae), and is more similar to

185 Live methicillin-resistant Staphylococcus aureus (MRSA)

186 ich is substantial during the aging of short-lived mice, is stabilized at low levels during the aging

187 readily scalable methods to sort millions of live migratory cancer and immune cells based on their sp

188 uman cells and in wild-type mice, but not in live mosquitoes.

189 that these reagents can be delivered to the live mouse brain and used to report TF occupancy.

190 burgdorferi proteins, lipid immunogens, and live mutants lead the design of canonical vaccines aimed

191 and semi-structured interviews among people living near these great apes to understand better their

192 lized at low levels during the aging of long-lived NMRs and bats.

193 respectively, and then dissipated with half-lives of 1.33 and 4.33 days, respectively.

194 Tuberculosis (TB) continues to claim the lives of around 1.7 million people per year.

195 coding RNAs that play important roles in the lives of both animals and plants.

196 dramatically affect the activities and half-lives of glycoproteins, effects that are relevant to und

197 Compared to protein-boosted regimens, half-lives of gp120-specific antibodies were longer but peak

198 ase 2019 (COVID-19) pandemic has claimed the lives of over one million people worldwide.

199 able to cure AML or significantly extend the lives of patients with a common mutation called FLT3-ITD

200 quence changes and typically have short half-lives of two to three generations.

201 , but they often overlook other species that live on corals and influence coral-microbe interactions.

202 We find that 294.5 million people live on tropical forest restoration opportunity land in

203 mminent death donation (IDD) is described as living organ donation prior to a planned withdrawal of l

204 bacteria constitute a remarkable example of living organisms for which motion can be easily controll

205 oluminescence, or the production of light by living organisms via chemical reaction, is widespread ac

206 t ancient protein superfamilies found in all living organisms.

207 Here we generate a living organoid biobank from patients with locally advan

208 ifically, large proteins often fold via long-lived partially folded intermediates, whose structures,

209 cesses across four major habitat types (free-living, particle-associated, biofilm on benthic stones a

210 perspective on migratory strategy of a long-lived pelagic seabird: Timings and destinations change p

211 Tuberculosis (TB) claims 1.5 million lives per year.

212 tic old-growth grassland species (e.g., long-lived perennials).

213 ects on their light absorption, thermal half-lives, photostationary states, fatigue, and quantum yiel

214 ing the subcellular redox dynamics of NAD in living plant tissues has been challenging.

215 s a widespread reproductive strategy in long-lived plants.

216 stability of the bone marrow-resident, long-lived plasma cell population, yet absence of this kinase

217 ing the generation of memory B cell and long-lived plasma cell responses.

218 which antigen drives the generation of long-lived plasma cells and memory B cells and highlight the

219 Living polymerizations currently play a central role in

220 ents have demonstrated ecological release in living populations.

221 These rapid and living practice points from the American College of Phys

222 measuring muscle growth over 12-h periods in live prefeeding larval zebrafish, we show that muscle gr

223 l ganglion cell activity in the fovea of the living primate.

224 cal probe reactions, in which unstable short-lived products have been synthesized and analyzed.

225 ory of past antigen exposure can confer long-lived protection against infections or tumors.

226 presentative of most Covid-19 patients, long-lived protective immunity against SARS-CoV-2 after prima

227 p53 is a short-lived protein with low basal levels under normal homeost

228 ly increased proteasomal degradation of long-lived proteins (the bulk of cell proteins) without affec

229 Strontium-90 ((90)Sr) is the major long-lived radionuclide derived from the Chernobyl accident,

230 al nervous system of lungfishes, the closest living relatives of all tetrapods.

231 r reconstructing the origin of their closest living relatives, the animals.

232 ships could differ from those of our closest living relatives.

233 V-1 infection due to the existence of a long-lived reservoir of latently infected cells.

234 New evidence will be incorporated using living review methods.

235 andscape', a clinical trials database and a 'living review' that distils the results of vaccine trial

236 society (e.g., energy conservation, healthy living, safe driving).

237 e background value, thereby realizing a long-lived sample of polar molecules in large electric fields

238 duals who were higher on general neuroticism lived shorter lives, individuals whose neuroticism was c

239 miting, at the 36th week of gestation with a live singleton pregnancy, and receiving the diagnosis of

240 ome species may hinge on their propensity to live socially, but in so doing, this is likely to affect

241 te the transfer of such a parasite with free-living stages between farmed and wild stocks.

242 e a blueprint for identifying naturally long-lived states in a decaying quantum system.

243 Living systems can form and recover complex chemical pat

244 nderstanding of mechanistic underpinnings of living systems might transform our ability to predict an

245 onequilibrium dynamics and thermodynamics of living systems, giving a few examples to demonstrate the

246 y, including the complexity and stability of living systems.

247 egeneration is a fundamental function of all living systems.

248 aterials that mimic the complex functions of living systems.

249 tion to occur and for life to arise from non-living systems.

250 situ two-dimensional affinity on individual live T cells from thymus, spleen, pancreatic lymph nodes

251 tless force for a world of longer, healthier lives, the 2030 Impact Goal is anchored in an understand

252 n, serve as environmental sentinels or guide living therapeutics.

253 Numerous features distinguish these "living therapies" from traditional medicines, including

254 Using live time-lapse imaging of primary resected tumors, we d

255 rugs and metabolic products in biofluids and living tissues holds great promise.

256 limited by the potential for laser damage to living tissues.

257 ey have contributed to many populations that live today, remains poorly understood.

258 However, fighting occurring in mice living together in long-term groups under standard labor

259 We found more carbon stocks in live trees, but a fewer number of standing-dead trees, a

260 ound healing, live lymph node sections and a live tumor microenvironment.

261 s to specifically study a population of long-lived tumor cells enriched in CSCs, which show stem-like

262 d we study them comparing the living and non-living two-dimensional systems self-organizing at the sp

263 in this study that immunization of mice with live typhoidal serovar, Salmonella Typhi, generates cros

264 st fishes, which comprise nearly one-half of living vertebrate species.

265 Live virus challenge of animals given SARS or MERS vacci

266 anoids with SARS-CoV-2 spike pseudovirus and live virus to demonstrate viral tropism for choroid plex

267 From 87,941,718 analyzed lives, we identified 16,292,018 opioid prescriptions fil

268 o calculate the prevalence and years of life lived with disability (YLDs) of 25 diseases, impairments

269 Delayed images, up to 10 half-lives with (18)F-FDG, revealed biologic insight and supp

270 h HIV (91% of 1353) were on ART; 1166 people living with HIV (88% of 1321 with available viral load)

271 nd, in intervention communities, 1228 people living with HIV (91% of 1353) were on ART; 1166 people l

272 Children living with HIV (CLHIV) receiving antiretroviral treatme

273 Of these, there were 246 children living with HIV (HIV+) who were initiated on ART before

274 safety and efficacy of IPT in pregnant women living with HIV (PWLHIV) are mixed.

275 Of 436 and 435 people living with HIV aged 18-49 years who participated in pre

276 f 2479 assessed for eligibility, 1315 people living with HIV and not on ART with detectable viral loa

277 We assigned women living with HIV and their child (oldest 3-8 years) to 1

278 need to address the holistic needs of people living with HIV beyond viral suppression.

279 Adolescents living with HIV face challenges to their wellbeing and a

280 (71.8-80.6), ART use among diagnosed people living with HIV increased from 68.0% (60.9-75.2) to 93.1

281 ation and food supplements provided to women living with HIV significantly increased weight and CD4+

282 ences, at study end the proportion of people living with HIV who were diagnosed was significantly hig

283 infection, increase ART use among all people living with HIV, and make substantial progress towards a

284 burden and low reinfection rate among people living with HIV, suggesting that microelimination is fea

285 o prevent recurrent HSIL after LEEP in women living with HIV.

286 Approximately 20% of children were living with HIV.

287 Cannabis use is frequent among people living with human immunodeficiency virus (HIV) and is as

288 g cause of mortality and morbidity in people living with human immunodeficiency virus (HIV) infection

289 a (KS), the most common malignancy in people living with human immunodeficiency virus (HIV)/AIDS.

290 Although people living with human immunodeficiency virus (PLWH) are at i

291 People living with human immunodeficiency virus (PLWH) are comm

292 ertension (PAH) is overrepresented in People Living with Human Immunodeficiency Virus (PLWH).

293 evant to treatment tolerability for patients living with indolent disease.

294 ction, a leading cause of morbidity in those living with SCI.

295 almost daily dry eye) more often agreed that living with Sjogren syndrome made every day a challenge

296 oblem worldwide, with over 36 million people living with the virus.

297 in; and (3) one-year survivors with pain who lived within 50 km from the study hospital.

298 thers who gave birth from 2008 to 2016 while living within 15 km of LAX were included in this analysi

299 iples carbon balance model with a prescribed live woody biomass turnover, applied at a forest researc

300 avital microscopy to quantify MT dynamics in live xenograft tumor models.