ライフサイエンスコーパス: liver tissue

1 s and cirrhosis in biopsied samples of human liver tissue.

2 c regulation of gene expression in the human liver tissue.

3 ion of the PDH E1alpha subunit (pE1alpha) in liver tissue.

4 ed obesity-induced inflammatory responses in liver tissue.

5 made to derive the organizing principles of liver tissue.

6 , are severely diminished in circulation and liver tissue.

7 sinusoids underlies the self-organization of liver tissue.

8 pling for histopathology of brain, lung, and liver tissue.

9 periostin and VCAM-1 was the inflamed sheep liver tissue.

10 etastatic liver cancer cells in premalignant liver tissue.

11 es of cancer cells, embryonic stem cells and liver tissue.

12 actor controlling LPCAT3 expression in mouse liver tissue.

13 em cells might be used to regenerate damaged liver tissue.

14 ratio, heme oxygenase-1 and glyoxalase 1 in liver tissue.

15 levels of XIAP, cIAP1, cIAP2, and cFLIP than liver tissue.

16 o extensively repopulate chronically injured liver tissue.

17 g of proteins in sections of mouse brain and liver tissue.

18 3D, Rab7 and Rab18) were determined in whole liver tissue.

19 ressive fibrosis and nodule formation in the liver tissue.

20 hepatocytes and histopathological changes in liver tissue.

21 of netrin-1 transcript and protein in murine liver tissue.

22 after surgical resection of large amounts of liver tissue.

23 ellular carcinoma (HCC) and matched nontumor liver tissue.

24 in the labeling of autophagy organelles from liver tissue.

25 tein, and mild necroinflammation remained in liver tissue.

26 t damage stomach, esophageal, intestinal, or liver tissue.

27 dothelial markers similar to those in normal liver tissue.

28 agents to depress the freezing point of the liver tissue.

29 nscription across normal, cirrhotic, and HCC liver tissue.

30 at define PMC identity compared with control liver tissues.

31 iral RNA demonstrating active replication in liver tissues.

32 ed reactive bile ducts compared with control liver tissues.

33 welling in mitochondria from mouse and human liver tissues.

34 ancer cell lines and not the adjacent normal liver tissues.

35 samples and their corresponding non-tumorous liver tissues.

36 ovarian tumors, but not nontumor prostate or liver tissues.

37 bolic chambers and by histologic analyses of liver tissues.

38 lymphocytes in vitro and by studies in human liver tissues.

39 ost-infected hamsters compared to uninfected liver tissues.

40 ry epithelial cells from healthy or diseased liver tissues.

41 issue microarrays of 105 HCCs and 7 nontumor liver tissues.

42 m samples and matched primary and metastatic liver tissues.

43 d in human HCC tissues compared to non-tumor liver tissues.

44 tenin activation in fibrotic/cirrhotic human liver tissues.

45 chronic HCV infection, but were detected in liver tissues.

46 ex vivo culture of patient-derived fibrotic liver tissues.

47 ession is very low or undetectable in normal liver tissues.

48 of human HCC tissues compared with non-tumor liver tissues.

49 s and microscopic and histologic analysis of liver tissues.

50 s were detected in murine blood, spleen, and liver tissues.

51 fewer neutrophil infiltration compared to CS liver tissues.

52 topathological evaluation of periodontal and liver tissues.

53 pCY & HepCO) from normal young and old human liver tissues.

54 We also studied human hepatocytes and liver tissues.

55 In liver tissues, a total of 428 differentially expressed g

56 tion of netrin-1 and its receptors in murine liver tissues after I/R injury.

57 Liver tissue analysis found the coexistence of an angiog

58 sue geometry from microscopy images of mouse liver tissue and analyzed it applying soft-condensed-mat

59 ores of gene expression from whole blood and liver tissue and assessed them for association with VTE.

60 We analyzed liver tissue and blood samples obtained before initiatio

61 essed by p16(INK4a) in situ hybridization in liver tissue and by senescence-associated beta-galactosi

62 prevented ischemia-induced cell swelling in liver tissue and dramatically improved LVR outcomes in s

63 iet, we observed higher MC concentrations in liver tissue and fecal matter.

64 at GCs stabilize HIF protein in intact human liver tissue and isolated hepatocytes.

65 tic fibrogenesis flux rates both directly in liver tissue and noninvasively in blood.

66 ortant for physiologically-relevant in vitro liver tissue and organ models, it is most often complete

67 ls of FXR isoforms and gene targets in human liver tissue and primary human hepatocytes from the Gene

68 novel insights into genome function in human liver tissue and provides a valuable resource for assess

69 study reinforces our previous findings using liver tissue and reveals new genes and likely tissue-spe

70 Mice were then sacrificed; liver tissue and serum were harvested.

71 this review, we discuss advances in modeling liver tissue and the latest developments in understandin

72 relation of herpesviruses in bile, blood and liver tissue and to investigate their association with b

73 state cancer samples, as well as 10 nontumor liver tissues and 20 nontumor prostate tissues, collecte

74 B cells were isolated from mouse and human liver tissues and analyzed by flow cytometry and enzyme-

75 ef brain, heart, kidney, large intestine and liver tissues and chemometric analysis enabled unique or

76 Liver tissues and cholangiocytes were collected, and liv

77 We obtained HCC and nontumorous liver tissues and clinical data from patients who underw

78 and subsequent distribution in the targeted liver tissues and hepatic tumors confirmed with MRI and

79 xpression data collected from the same human liver tissues and high-resolution promoter-focused chrom

80 administration of carbon tetrachloride, and liver tissues and HSCs were collected and analyzed.

81 ly, miR-139-5p was upregulated in metastatic liver tissues and negatively correlated with genes assoc

82 This population was absent in nondiseased liver tissues and peripheral blood.

83 anscriptome analyses were carried out in the liver tissues and rRNA meta-transcriptome analysis were

84 , performed RNA sequencing and proteomics of liver tissue, and integrated these data with serum metab

85 in a mouse model downregulated CIDEB in the liver tissue, and knockout of the CIDEB gene in a hepato

86 numbers of inflammatory cells in adipose and liver tissue, and steatosis; and these effects were exac

87 erate metastatic stem cells in preneoplastic liver tissue are not well understood.

88 xicity, regeneration and clonal structure of liver tissue as it progresses from health to disease.

89 The gold content of tumor and liver tissue at 1 hour or 24 hours after injection was q

90 cell-to-cell DNA methylation variability in liver tissue, based on comparing the methylation status

91 dies were performed in human control and PSC liver tissue biopsies, serum, and bile.

92 The procedure was established on liver tissue but can be used to isolate ECs from other o

93 Anti-CD3 did not differentially reach BM and liver tissues but was more effective in reducing graft a

94 1/MTA1dE4 in their paired nontumor and tumor liver tissues by using RT-qPCR.

95 For experiments on liver tissue, calibration by spiked tissue homogenates a

96 To determine whether lipid profiling of liver tissue can identify metabolic signatures associate

97 n factor (TF) DNA-binding activity for mouse liver tissues collected from embryonic day 12.5 (E12.5)

98 f genome-wide messenger RNA expression using liver tissues collected from mice fed a standard chow di

99 We also analyzed transcriptomes of liver tissues collected from mice on a choline-deficient

100 physiologic and metabolic aspects of intact liver tissue compared with two-dimensional culture syste

101 Human liver tissues contained a significant proportion of IgA-

102 2013 through May 2017, along with tumor-free liver tissues (control tissues) and peripheral blood sam

103 d and accurate production of human acellular liver tissue cubes (ALTCs) using normal liver tissue uns

104 Oxidative stress plays a critical role in liver tissue damage and in hepatocellular carcinoma (HCC

105 During ruxolitinib treatment, liver tissue damage receded concomitantly with a decreas

106 ised to respond to the release of IL-33 upon liver tissue damage through expression of type 2 cytokin

107 Analysis of chronically inflamed liver tissue demonstrated accumulation of SCARF-1 at sit

108 eNOS dysfunction observed in platelets and liver tissue didn't match with FMD.

109 tribute to optimal lymphocyte positioning in liver tissue during chronic hepatitis.

110 patocytes maintain the ability to regenerate liver tissues during chronic damage without generating m

111 matched maternal serum, placenta, and fetal liver tissues during mid-gestation among a geographicall

112 an islets clearly with high contrast against liver tissue, enabling accurate quantitation of islet ma

113 rous biomedical applications, especially for liver tissue engineering, cell preservation, and drug to

114 o current obstacles in disease modelling and liver tissue engineering.

115 position is essential for the advancement of liver tissue engineering.

116 lymphocytes, and immunochemistry staining of liver tissues for assessing necrosis, platelet depositio

117 thway components in tumor and non-neoplastic liver tissue from 7 pediatric patients with moderately d

118 tein levels were evaluated in Huh7 cells, in liver tissue from a rat model of NAFLD, and in liver bio

119 Furthermore, liver tissue from AH patients demonstrated an enrichment

120 antitative IMS experiments were performed on liver tissue from an animal dosed in vivo.

121 Immunohistochemical characterization of liver tissue from an index case of atabecestat-mediated

122 ency of cII target gene was 3.46 x 10(-5) in liver tissue from control fish, which increased by 1.4-f

123 Notably, liver tissue from Ercc1(/-) mice fed ad libitum showed p

124 nts with AH or alcoholic cirrhosis or normal liver tissue from hepatic resection.

125 In fibrotic liver tissue from mice and patients, hepatic S1P levels

126 n systems, and in vivo ribosome profiling of liver tissue from mice carrying genomic deletions of 3'

127 d to be increased in isolated HSCs and whole liver tissue from Nlrp3(L351P) Lrat Cre mice compared to

128 ire metabolic profiles of muscle, heart, and liver tissue from normally slaughtered and dead on arriv

129 f JNK in drug-induced liver injury (DILI) in liver tissue from patients and in mice with genetic dele

130 d metabolomic and transcriptomic analyses of liver tissue from patients with AH or alcoholic cirrhosi

131 et, N = 167 and validation set, N = 225) and liver tissue from patients with cirrhosis without HCC (N

132 NMP altered gene-expression profiles of liver tissue from proinflammation to prohealing and rege

133 ata from healthy volunteers (n = 11), normal liver tissue from public repositories and patients witho

134 ere, we performed a fluorine mass balance on liver tissues from 11 different species using a combinat

135 cinoma (HCC) using paired tumor and adjacent liver tissues from 159 patients.

136 We analyzed the expression data of liver tissues from 216 patients with cirrhosis without H

137 pared gene expression patterns with those of liver tissues from 25 patients with nonalcoholic steatoh

138 atitis B surface antigen and core antigen in liver tissues from 26 patients with chronic HBV infectio

139 bal changes in postmortem gene expression in liver tissues from 27 Italian and United States corpses:

140 nalyzed gene expression profiles of nontumor liver tissues from 392 patients with early-stage HCC (tr

141 ed virological factors and AKT expression in liver tissues from 56 HCC patients with better prognoses

142 strogen receptor (GPER1) in HCC and nontumor liver tissues from 68 patients by immunohistochemistry.

143 We collected blood and liver tissues from Atp7b(-/-) and Atp7b(+/-) (control) r

144 We collected and analyzed liver tissues from C57BL/6 (control), LysM-EGFP, B6 ACTb

145 Liver tissues from control mice given CCl(4) had signifi

146 n comparing gene expression profiles between liver tissues from different mouse models of NAFLD and p

147 Liver tissues from FXR-knockout mice had reduced express

148 vitro (Huh7-S10-3 liver cells) and in vivo (liver tissues from HEV-infected pigs); however, ISG15 is

149 at regulate fibrosis genes were increased in liver tissues from infants who did not survive for 2 yea

150 In studies of liver tissues from infants with cholestasis, we identifi

151 Whole-transcriptome sequence analyses of liver tissues from mice and patients with Alagille syndr

152 We collected liver tissues from mice that express a constitutively ac

153 performed quantitative proteomic analyses of liver tissues from mice to evaluate these functions and

154 Liver tissues from mice with liver-specific hemizygous d

155 yhead like transcription factor 2 (GRHL2) in liver tissues from mice.

156 Liver tissues from MYO5B(P663L) piglets had alterations

157 Analyses of liver tissues from NASH patients reveal that YAP is incr

158 rs of chronic HCV patients that is absent in liver tissues from nonviral hepatitis or healthy subject

159 mRNA, a target of MIR122, were increased in liver tissues from patients and mice with ALD, compared

160 Fibrotic liver tissues from patients and rodents (mice and rats)

161 of PFKFB3 protein were increased in fibrotic liver tissues from patients compared with non-fibrotic l

162 Genetic analyses of liver tissues from patients have provided important info

163 nt cirrhotic liver samples, and 10 non-tumor liver tissues from patients undergoing resection for hep

164 Many mRNAs expressed at high levels in liver tissues from patients with 2-year transplant-free

165 Levels of GRHL2 also were increased in liver tissues from patients with ALD, compared with cont

166 IL17 is up-regulated in liver tissues from patients with BA, compared with contr

167 Liver tissues from patients with chronic HCV infection h

168 We collected liver tissues from patients with cirrhosis (n = 43), HCC

169 Liver tissues from patients with cirrhosis and HCC revea

170 nd the ICF gene expression pattern in 50% of liver tissues from patients with cirrhosis without HCC a

171 We obtained nontumor liver tissues from patients with colorectal carcinoma un

172 cirrhosis without HCC and in 60% of nontumor liver tissues from patients with early-stage HCC.

173 Liver tissues from patients with liver disease had incre

174 ne expression signatures similar to those of liver tissues from patients with NASH.

175 In liver tissues from patients with PBC and dnTGF-betaRII m

176 In liver tissues from patients with primary sclerosing chol

177 Hepatocytes in liver tissues from patients with WD and from Atp7b(-/-)

178 iopsies from 2 patients with WD in Italy and liver tissues from patients without WD (control).

179 eased levels of CPEB1 and CPEB4 in cirrhotic liver tissues from patients, compared with control tissu

180 CRLM tissues compared with healthy, adjacent liver tissues from the same patients.

181 neutrophil extracellular traps in kidney and liver tissues from untreated rats, consistent with the t

182 rm long-term expanding organoids that retain liver tissue function and genetic stability.

183 histopathologic examination of gingival and liver tissues; immunohistochemistry to cells positive fo

184 revealed that exosomes mirrored whole human liver tissue in terms of the families of proteins presen

185 ffective protocols aimed at recreating human liver tissue in vitro.

186 oproteins (RNPs) to cells in vitro and mouse liver tissue in vivo with engineered ectosomes.

187 enous genes in cell lines in vitro and mouse liver tissue in vivo, paving the way toward applications

188 Pathologic changes in kidney and liver tissues in a rat model of major burn and endotoxin

189 LPS challenge can activate CREBH in mouse liver tissues in a toll-like receptor (TLR)/MyD88-depend

190 Rbeta expression is increased in adipose and liver tissues in obese high-fat fed mice.

191 estinal system, especially for intestine and liver tissues in which aberrant and deregulated repair r

192 uman APOBEC3A expression in murine colon and liver tissues increases tumorigenesis.

193 healthy individuals but highly expressed in liver tissue, indicating an ectopic origin from the live

194 and (1866) reduced HFD-increased adipose and liver tissue inflammation, adipocyte differentiation, an

195 c sinusoidal channels and positioning within liver tissue is a critical event in the development and

196 iciency in mouse embryo fibroblasts or mouse liver tissue is associated with replicative stress and m

197 reased in KCs and that level of YAP in human liver tissues is positively correlated with expression o

198 In human liver tissues, levels of FXRalpha2 varied significantly

199 Recently, a liver tissue model conducive to hepatotoxicity testing w

200 he motor cortex, hippocampus, cerebellum and liver tissue of 5 year old transgenic sheep and matched

201 ) for herpesvirus 1-8 DNA in bile, blood and liver tissue of 73 patients after first LT and analyzed

202 l K- and Ru L2,3-edges) in tumor, kidney and liver tissue of a SW480 bearing mouse.

203 E) residues and gene expression in embryonic liver tissue of double-crested cormorants (Phalacrocorax

204 MCPIP1 expression level was higher in the liver tissue of HBV-infected patients and mice.

205 wed significantly elevated expression in the liver tissue of NASH patients.

206 flammation or fibrosis was found in adjacent liver tissues of 3 patients who underwent liver resectio

207 atients as well as the adjacent noncancerous liver tissues of a subset of HCC patients with a relativ

208 n adducts, and depletion of glutathione from liver tissues of control mice, resulting in ER stress an

209 rs of ACSL1, we examined ACSL1 expression in liver tissues of hamsters fed a normal diet, a high fat

210 rmed in non-cancerous and adjacent cancerous liver tissues of HCC patients.

211 number of IL17a-positive gammadelta T cells liver tissues of mice with BA was associated with increa

212 bryonic fibroblasts as well as in muscle and liver tissues of mutant mice.

213 an immune-related gene expression pattern in liver tissues of patients with early-stage HCC, called t

214 ation between levels of YAP/TAZ and CYR61 in liver tissues of patients with high-grade nonalcoholic s

215 ve pressure, observed in chronically damaged liver tissues, on polyploid cells.

216 ing neoplasmatic process which begins in the liver tissue or in the biliary tracts.

217 as the presence of the HCV genome in either liver tissue or peripheral blood monocytes, despite cons

218 ssues, compared with T cells from tumor-free liver tissues or blood.

219 urrent single-cell model, whether of primary liver tissue origin, from liver cell lines, or derived f

220 D4 T cells colocated within freshly isolated liver tissue (p < 0.001).

221 Curiously, despite having more marked liver tissue pathology, 9142-primed mice also had spleni

222 mice with knockdown of XBP1, we observed of liver tissue persistent endoplasmic reticulum stress, de

223 3 present on organelles isolated from murine liver tissue prior to CE-LIF analysis.

224 ctly from the surface of ultrathin slices of liver tissue prior to detection by high-resolution mass

225 mouse HSCs, human LX2 HSCs, human cirrhotic liver tissues, rats and mice with liver fibrosis (due to

226 Elevation of CXCL1 in premetastatic liver tissue recruited CXCR2-positive myeloid-derived su

227 n of PPARdelta in cultured hepatic cells and liver tissue reduced LPCAT3 mRNA levels, and exogenous o

228 d transplant rejection yet is beneficial for liver tissue regeneration.

229 th hepatitis C virus-associated cirrhosis or liver tissues removed during transplantation; healthy hu

230 s as an important Wnt-producing regulator of liver tissue repair following localized liver injury.

231 ether or how the acute-phase changes promote liver tissue resilience during infections is unclear.

232 and Scd-1 Untargeted lipidomic profiling in liver tissue revealed 132 lipid species, including sphin

233 e analysis of immunostaining were applied to liver tissue samples from infants with BA.

234 ations in KRAS or BRAF genes in pathological liver tissue samples from patients with hepatic vascular

235 so compared gene expression profiles between liver tissue samples from patients with nonalcoholic ste

236 We obtained liver tissue samples from patients with primary sclerosi

237 clinical specimens, cell lysates, and mouse liver tissue samples, demonstrating its highly sensitive

238 proteome of E. coli, mouse brain, and mouse liver tissue samples, respectively.

239 using ChIP-seq data for 20 DAPs in two human liver tissue samples.

240 Liver tissue sections from mice with and without abdomin

241 Chromatin immunoprecipitation analyses of liver tissue showed that at 6 hours after PH, liver XBP1

242 NMP liver tissues showed less necrosis and apoptosis in the

243 0%, respectively), a higher tumour-to-normal-liver-tissue signal ratio (5.33 versus 1.45) and an enha

244 a-AASA) and pipecolic acid both in brain and liver tissues, similar to the biochemical picture in ALD

245 PTX3 was evaluated in cultured human cells, liver tissue slices, and mice with acute-on-chronic live

246 ound that our single blind study using eight liver tissue-specific gene biomarkers (e.g. AMBP and AHS

247 d immune-related gene expression patterns in liver tissues surrounding early-stage HCCs and chemoprev

248 Histological analysis of the periodontal and liver tissues sustains the link between periodontal and

249 pectrum of clinical disorders and changes in liver tissue that can be detected by pathology analysis.

250 The liver tissue that surrounded the tumors showed no histol

251 In nodules of human cirrhotic liver tissue, there was no evidence of chromosome-level

252 ug compounds in both human cartilage and dog liver tissue to be visualized using MALDI-2, whereas lit

253 an hepatocellular carcinoma (HCC) and benign liver tissue to identify miRNA target sites transcriptom

254 Rejection resulted in distinct blood and liver tissue transcriptional changes in patients who wer

255 ular liver tissue cubes (ALTCs) using normal liver tissue unsuitable for transplantation.

256 for investigation of hepatotoxicity in human liver tissue upon applying drug concentrations relevant

257 evelopment of EMT-positive mCSCs in HCC-free liver tissue upon chronic inflammation.

258 study undertook sampling of brain, lung, and liver tissue using core biopsy needles, blood and cerebr

259 We assessed cytokine profiles of liver tissues using a multiplexed array.

260 Liver tissue was analyzed for Sirius Red staining and hy

261 emoved during transplantation; healthy human liver tissue was obtained from a commercial source (cont

262 Liver tissue was obtained from healthy liver donors (n =

263 Human liver tissue was perfused over a 30 hour period with hou

264 Next-generation sequencing of mouse liver tissues was performed from control, VPA, and VPA +

265 transporter 1 (SLC29A1) in HCC compared with liver tissue, we conducted a proof-of-concept study eval

266 Using human fetal liver tissue, we found that the mRNA of CYP26A1 and CYP2

267 Based on studies of mice and human liver tissues, we found the liver to be a site of IgA pr

268 Serum, hepatocytes and liver tissue were analyzed.

269 Human liver tissues were also analyzed by histology.

270 Liver tissues were analyzed by histology and by immunobl

271 Liver tissues were analyzed by histology, immunohistoche

272 Human and mouse liver tissues were analyzed by histology, immunohistoche

273 od samples were analyzed by biochemistry and liver tissues were analyzed by histology, RNA sequencing

274 Liver tissues were analyzed by immunohistochemistry, imm

275 Liver tissues were collected 14 months after delivery; g

276 Liver tissues were collected and analyzed by histology a

277 Liver tissues were collected and analyzed by histology a

278 Blood and liver tissues were collected and analyzed by histology a

279 Pancreata and liver tissues were collected and analyzed by histology,

280 Liver tissues were collected and analyzed by immunohisto

281 of liver failure (alanine aminotransferase); liver tissues were collected and analyzed by quantitativ

282 Liver tissues were collected and analyzed by RNA sequenc

283 weights were measured, and fecal, blood, and liver tissues were collected and analyzed.

284 inhibitor nintedanib or vehicle (controls); liver tissues were collected and histology, transcriptom

285 Liver tissues were collected at different timepoints dur

286 Liver tissues were collected before surgery and at 6 and

287 Liver tissues were collected from mice and analyzed by h

288 Liver tissues were collected from mice and analyzed hist

289 Serum and liver tissues were collected; hepatocytes and liver mono

290 Liver tissues were obtained from patients with primary s

291 ycosylation sites were identified from mouse liver tissues, which showed the ability to enrich glycop

292 okines and reduced the expression of CHOP in liver tissues while dramatically increasing hepatic HO-1

293 lating the spatial distribution of lipids in liver tissue with disease progression using advanced mas

294 We combined decellularized human liver tissue with electrospun polymers to produce a nich

295 ogel phantom, a solution sample, and porcine liver tissue with exchanged parameters by perfusion of t

296 ed them to be distinguished from nontumorous liver tissue with high accuracy [c: AUC = 0.88 with 95%

297 al responsiveness was confirmed in assays of liver tissue with variable durations of ischemia, which

298 15 could recognize S. japonicum eggs laid in liver tissues with a detection ratio of 80.5%.

299 The liver tissues with the ICF gene expression pattern had 3

300 Patients with cirrhosis and liver tissues with the immunosuppressive profile (10% of