ライフサイエンスコーパス: lives

1 gs are highly valued and integrated in human lives).

2 as the promise of robots enhancing our daily lives.

3 t evolutionary success and our present daily lives.

4 reat efficacy for OUD treatment and can save lives.

5 rimental outcomes, in this case protein half-lives.

6 dynamics is important to many aspects of our lives.

7 environments combine to create unique human lives.

8 iggered a pandemic that is now claiming many lives.

9 capacitating conditions that markedly impact lives.

10 effort may change over the course of males' lives.

11 of numerous new advanced materials into our lives.

12 ents from their families at the end of their lives.

13 ys to connect with important people in their lives.

14 ults live not only longer but also healthier lives.

15 as science, the court room, and our everyday lives.

16 roductive acceleration if they also led long lives.

17 d forms displayed significantly shorter half-lives.

18 rapidly worldwide and threatens millions of lives.

19 's pursuit of a world with longer, healthier lives.

20 t, preventing myocardial infarction may save lives.

21 ple and has claimed hundreds of thousands of lives.

22 tical stages of sepsis, thereby saving human lives.

23 ve revolution has had for people's emotional lives.

24 their breadths, potencies, and in vivo half-lives.

25 idespread use of LIBs in every aspect of our lives.

26 , with distinct physical properties and half-lives.

27 learning modes and methods throughout their lives.

28 agents in the healthy continuation of their lives.

29 ost PV patients can lead long and productive lives.

30 ital signs and timely administration to save lives.

31 e at risk, and suppress transmission to save lives.

32 ed to negative impacts on women's and girls' lives.

33 nfected individuals to live long, productive lives.

34 aphylaxis so that it did not take over their lives.

35 icity, increased efficacy, and extended half-lives.

36 r treatment is of dire urgency and will save lives.

37 can significantly reduce mortality and saves lives.

38 le populations may save or cost thousands of lives.

39 tions and the impact of surgery on patients' lives.

40 ized by worry and vulnerability lived longer lives.

41 st 99% and save more than 62 million women's lives.

42 and therefore make a difference in patients lives.

43 active biomedical sensing role in our daily lives.

44 and poses a great burden on patients' daily lives.

45 erties and substantially extend peptide half-lives.

46 rease science engagement in children's daily lives.

47 quitous, revolutionizing many aspects of our lives.

48 rrected, it could save lives-including Black lives.

49 ight similarly curtail transmission and save lives.

50 to minimize the impact of coronavirus on our lives.

51 tless force for a world of longer, healthier lives.

52 role that an 'attention economy' has in our lives(1).

53 reduced model [7 rates, 2 KD's, enzyme half-lives~1 min] predicted the measured clot elution rate of

54 )I-MIBG despite the large difference in half-lives (100 vs. 13.2 h).

55 ulfate, respectively) results in rapid (half-lives ~20-60 min), photochemically induced nucleophile i

56 r-labeled antibodies beyond 2-3 isotope half-lives (7-10 d), after which a poor signal-to-noise ratio

57 cterized by very low clearance and long half-lives across preclinical species, resulting in a PK prof

58 tion that radiopharmaceutical effective half-lives across the population are gaussian-distributed (i.

59 these medications for the remainder of their lives after diagnosis.

60 Half-lives also vary globally between cell lines, with median

61 mmon Era), and it resulted in the loss of 59 lives and $25 billion in damages across the southeastern

62 or all Americans would save more than 68 000 lives and 1.73 million life-years every year compared wi

63 cal disease and a threat to 65 million human lives and 100 million small and large livestock animals

64 der the 25% backlog scenario, 811 additional lives and 14 873 life-years lost under the 50% backlog s

65 oss months 1-3 would result in 90 additional lives and 1662 live-years lost due to diagnostic delays

66 he 50% backlog scenario, and 1231 additional lives and 22 635 life-years lost under the 75% backlog s

67 per patient) would result in 181 additional lives and 3316 life-years lost as a result of a backlog

68 for the 25% backlog scenario, 183 additional lives and 3362 life-years lost under the 50% backlog sce

69 the 50% backlog scenario, and 276 additional lives and 5075 life-years lost under the 75% backlog sce

70 backlog of referrals of 25%, 361 additional lives and 6632 life-years lost for a 50% backlog of refe

71 fter lockdown would result in 401 additional lives and 7332 life-years lost due to diagnostic delays

72 50% backlog of referrals, and 542 additional lives and 9948 life-years lost for a 75% backlog in refe

73 la virus (EBOV) outbreaks can claim numerous lives and also devastate the local health infrastructure

74 motor skills is a central part of our daily lives and can provide a model for rehabilitation after a

75 tion share a fundamental purpose to save the lives and ease the suffering of people caught in acute c

76 containing highly pathogenic viruses, saving lives and economy is evident.

77 era of modern medicine have saved countless lives and enhanced patient well-being, it is clear that

78 ure the impact of heart failure on patients' lives and is strongly associated with clinical events ov

79 fall short of only altering the binding half-lives and keeping other parameters of the interaction un

80 climate change and its interplay with human lives and landscapes.

81 l comforting of families as they honored the lives and legacies of their loved ones while inspiring c

82 umbers, we estimated the aggregate number of lives and life-years lost in England for per-patient del

83 inment, and hence have the potential to save lives and limit environmental disasters.

84 sis that silently disables families and ends lives and livelihoods around the world.

85 impact on society worldwide, threatening the lives and livelihoods of many.

86 o In this study, we evaluated the serum half-lives and permeability into the brain and cerebrospinal

87 Hurricanes that damage lives and property can also impact pollutant sources and

88 jor TCs pose, by far, the greatest threat to lives and property.

89 aquifer vulnerability and potential loss of lives and property.

90 gests that OPEs with longer atmospheric half-lives and relatively high octanol-air partitioning coeff

91 d dynamic proteomics to profile protein half-lives and report that INM and ER residents turn over at

92 urs, which can have a severe impact on their lives and that of their families.

93 inues, with devasting consequences for human lives and the global economy(1,2).

94 ir glaucoma interfered more with their daily lives and were more worried about losing vision from gla

95 Spectral changes, half-lives, and bleaching rates were determined.

96 e production rates, quantum yields, and half-lives, and found that strong electron-donating groups en

97 accines around the globe, saving millions of lives, and highlighting the power of immunization to pre

98 ades nearly every social aspect of our daily lives, and its disruption is a significant factor in men

99 titioners, improve epidemic management, save lives, and reduce the economic impact of outbreaks.

100 o account for the full array of adolescents' lives, and variation in how ethical review committees as

101 l and scientific integrity, given that human lives are at stake.

102 Compartment-specific degradation half-lives are essential pieces of information in the regulat

103 bility distortion.SIGNIFICANCE STATEMENT Our lives are peppered with uncertain, probabilistic choices

104 Although a large proportion of our lives are spent participating in social interactions, th

105 sion rates, quantum yields, and thermal half-lives) are largely retained.

106 PFPeS and PFHpS showed average half-lives as 0.63 and 1.46 y, respectively.

107 The same organism that lives as a commensal and is transmitted in both health-c

108 stances plays an important role in our daily lives as well as in ecological and technological worlds.

109 ent to accurately predict environmental half-lives, as intrinsic differences in the reaction mechanis

110 Saving lives at ages below life expectancy is the key to increa

111 on that commonly occurs in nature and in our lives at any time and any place.

112 hild Health and Human Development and Saving Lives at Birth Grand Challenges.

113 Reaction half-lives at pH 7 ranged from milliseconds to hours.

114 hmic drugs were discontinued at least 5 half-lives before the initiation of ivabradine.

115 generated radicals are persistent, with half-lives between 1 and 7 d and display no degradation upon

116 ntury-specifically, how they partition their lives between freshwater habitats and the ocean.

117 ral exposures and favorable elimination half-lives both in rats and dogs.

118 ificial agents are increasingly entering our lives, but how the human brain responds to these new art

119 RS as a significant challenge in their sons' lives, but one that could be overcome.

120 mpounds with relatively long biological half-lives, but their use for compounds with relatively short

121 p (AA), which significantly impact patients' lives by damaging their appearance and function.

122 Human capabilities may lead to fulfilling lives by enabling people to achieve a valuable combinati

123 ic shock therefore has the potential to save lives by opening an early window of intervention.

124 4), and LTE(4), have different biologic half-lives, cellular targets, and receptor specificities.

125 disaccharides generally exhibited lower half-lives compared to monosaccharides; whereas, 1 -> 6 disac

126 We as humans do not value lives consistently.

127 ty of men to remain fertile throughout their lives depends upon establishment of a spermatogonial ste

128 indeed be possible to read across from half-lives determined in highly efficient biotransformation e

129 Here, we explore the possibility to use half-lives determined in highly time- and work-efficient biot

130 In a desperate attempt to improve patients' lives different regions of the neuraxis were ablated.

131 tified nuclides include those that have half-lives down to [Formula: see text].

132 wledge gap, we investigated dissipation half-lives (DT50s) of 31 substances (mainly pharmaceuticals)

133 Dissipation half-lives (DT50s) were highly variable between the tested co

134 a pervasive disease that affects millions of lives each year in equatorial regions of the world.

135 smodium spp. that takes an estimated 435,000 lives each year, primarily among young African children.

136 Infectious diseases claim millions of lives each year.

137 ~40 million people and claims nearly 300 000 lives each year.

138 they transmit claim at least a million human lives every year globally.

139 tella germanica L.) is a worldwide pest that lives exclusively in human environments.

140 equences of financial toxicity to survivors' lives following acute respiratory distress syndrome.

141 We experimentally determined half-lives for 52 structurally diverse agrochemical active in

142 treatment plants over different GAC service lives for controlling 61 unregulated DBPs, 9 regulated D

143 Moreover, relative half-lives for individual miRNAs vary between cell types, imp

144 bronic coherence at the conical intersection lives for several hundred femtoseconds and can be measur

145 Vaccines save millions of lives from infectious diseases caused by viruses and bac

146 nt of effective vaccines has saved countless lives from infectious diseases, the basic workings of th

147 d mixtures of chemicals to predict soil half-lives from regulatory simulation studies.

148 t of RNA-DNA hybrids per cell and their half-lives genome-wide.

149 patients (10.6%) had parasite clearance half-lives greater than 5 hours with pfkelch13 polymorphism a

150 fections with longer parasite clearance half-lives (>5 hours) were observed in 12% isolates.

151 ens that acquired fractures earlier in their lives had fewer DCX(+) neurons in the caudal hippocampal

152 nzo-p-dioxin and dibenzofuran (PCDD/Fs) half-lives (HLs) in soil is presented.

153 Over half of the world's population lives in a country where the canine rabies virus variant

154 egressing the experimentally determined half-lives in activated sludge against average soil half-live

155 hierarchy of protein stabilities (with half-lives in descending order) as follows: LDB1 > SSBP > LMO

156 ortion of species spend all or part of their lives in groups, with group coordination playing an impo

157 Bats live extremely long lives in highly complex and dynamic social environments,

158 eir wild ancestor, the Red junglefowl, which lives in humid and sub-humid tropical areas.

159 We demonstrate that this species lives in large, multi-male, multi-female groups that ass

160 One that lives in Mexican rivers and various convergent forms tha

161 Nowadays, 23% of the world population lives in multi-million cities.

162 apable of plastic changes in appearance, and lives in multiple environments.

163 erception.SIGNIFICANCE STATEMENT We live our lives in social groups where complex relationships form

164 and multivariate models for predicting half-lives in soil by regressing the experimentally determine

165 to show that the placozoan Trichoplax sp. H2 lives in symbiosis with two intracellular bacteria.

166 textiles, which will soon revolutionize our lives in the era of Internet of Things.

167 e retina of the closest living ancestor that lives in the rivers and two independently adapted of cav

168 itioned themselves as living abnormal family lives in the stage from normal to abnormal.

169 This symbiont lives in the ventral epithelial cells of Trichoplax, pro

170 itor - the red jungle fowl (Gallus gallus) - lives in tropical ecosystems and does not exist in north

171 ically plagued by instability and short half-lives in vivo.

172 at if sleep loss is corrected, it could save lives-including Black lives.

173 higher on general neuroticism lived shorter lives, individuals whose neuroticism was characterized b

174 The protozoan parasite Toxoplasma gondii lives inside a vacuole in the host cytosol where it is p

175 insects can have surprisingly complex social lives involving a network of individually differentiated

176 use for compounds with relatively short half-lives is not clear and may require either a longer deplo

177 cin (C(MAX) = 400 ng/ml)) and different half-lives (isoniazid and pyrazinamide (C(MAX) = 28,900 ng/ml

178 at transplant fulfills the mission of saving lives, it is imperative to consider the consequences not

179 They are associated with longer half-lives, larger-scale production, and lower positron range

180 uperior stability and longer biological half-lives likely due to opposite chirality and thus protecti

181 the same migratory patterns throughout their lives, little is known on the time required for immature

182 Apart from the lives lost, survivors of semiautomatic rifle- and shotgu

183 ng quiet rest and suggests that in our daily lives, moments of unoccupied rest may serve an essential

184 Africa, at least one-sixth of the population lives more than 2 h away from a public hospital, and one

185 lution was extremely rapid; the average half-lives of (129)I(-) and (129)IO(3)(-) in soil solution we

186 injection, representing approximately 9 half-lives of (89)Zr and with a total residual activity of on

187 respectively, and then dissipated with half-lives of 1.33 and 4.33 days, respectively.

188 and linear PFOS isomers showed average half-lives of 1.77, 2.87, and 2.93 y, respectively.

189 We studied the dissipation half-lives of 10 micropollutants in sediment-water incubation

190 solved with this dosing strategy, saving the lives of a minimum of 2423 children in these countries a

191 has proven its great potential by saving the lives of a proportion of late stage patients with immuno

192 e success of this approach in extending half-lives of a wide range of biologics, it is unclear whethe

193 otein in WT mice demonstrated prolonged half-lives of alpha-Gal A in tissues and plasma.

194 Tuberculosis (TB) continues to claim the lives of around 1.7 million people per year.

195 come a global pandemic that has affected the lives of billions of individuals.

196 f thousands, and utterly disrupted the daily lives of billions of people around the world.

197 estricts the opportunities for long, healthy lives of Black Americans and other historically disenfra

198 coding RNAs that play important roles in the lives of both animals and plants.

199 d treatment continue to prolong and save the lives of cancer patients globally.

200 dramatically affect the activities and half-lives of glycoproteins, effects that are relevant to und

201 Compared to protein-boosted regimens, half-lives of gp120-specific antibodies were longer but peak

202 d profile in vitro, possessed metabolic half-lives of greater than 1 h in mouse liver microsomes (MLM

203 We found cell division-independent half-lives of H2B-FPs to be short, which had led to overestim

204 uses cause chronic disease, and threaten the lives of immunosuppressed individuals.

205 l research is about saving and improving the lives of individuals with cancer.

206 Moreover, favorable half-lives of iodine isotopes result in much less challenging

207 n of unwanted proteins and also control half-lives of key cellular regulatory factors.

208 The Coulombic efficiencies and cycle lives of LMBs with ethylene carbonate (EC), dimethyl car

209 a legacy that will continue to influence the lives of many for decades to come.

210 e clinical management of GERD influences the lives of many individuals and is responsible for substan

211 the allergic phenotype has likely saved the lives of many more mammals than have ever died from alle

212 ut the world and has resulted in the loss of lives of many souls.

213 rmediates are unstable, commonly having half-lives of minutes to hours(6).

214 , and nematodes, thereby specifying the half-lives of most short-lived miRNAs.

215 wide RNA decay pathway that reduces the half-lives of mRNAs based on overall 3' UTR structure formed

216 es holds the promise of revealing the secret lives of nucleosomes, potentially bridging the gaps in o

217 ase 2019 (COVID-19) pandemic has claimed the lives of over one million people worldwide.

218 d at achieving long-term improvements in the lives of patients and families.

219 plant nephrology will ultimately improve the lives of patients suffering from kidney disease.

220 Organ shortage continues to limit the lives of patients who require liver transplantation.

221 able to cure AML or significantly extend the lives of patients with a common mutation called FLT3-ITD

222 re creating new opportunities to improve the lives of patients with DoC.

223 (MIRI) is a serious threat to the health and lives of patients without any effective therapy.

224 iratory syndrome coronavirus has changed the lives of people around the world with a huge impact on e

225 oximately two orders of magnitude, with half-lives of per-site recovery of steady-state methylation l

226 brief systemic and intraarticular (IA) half-lives of relaxin-2: 0.96 h and 0.62 h, respectively.

227 s potential to reduce suffering and save the lives of rich and poor patients alike.

228 Half-lives of RSV-specific antibodies in infants approximated

229 Shelf-lives of samples, except for KPJ, ended after 12 weeks o

230 d the second another intermediate, with half-lives of seconds.

231 However, short half-lives of such labile ligands due to nuclease attack and

232 ion formation could dramatically improve the lives of surgical patients.

233 ve is made salient participants preserve the lives of that perspective, i.e. the passenger shifts tow

234 xtrapolate unfolding rate constants and half-lives of the crystallins in the absence of the denaturan

235 n activated sludge against average soil half-lives of the same chemicals extracted from regulatory da

236 serum and urine) and to estimate serum half-lives of the short-chain PFAS together with legacy PFAS.

237 mity, that he stated would "make or mar" the lives of the students he was addressing.

238 ost unremarkable of topoisomerases, the many lives of these type IA topoisomerases are now being prog

239 The biological half-lives of total cyantraniliprole were 11.3 and 9.4 days f

240 ined health care resources, and impacted the lives of transplant professionals.

241 By measuring the half-lives of two PARP1-mRNA targets we found that the half-l

242 quence changes and typically have short half-lives of two to three generations.

243 Although the decisions of our daily lives often occur in the context of temporal and reward

244 Keen to ensure that the legacy of Linnaeus lives on in the age of microbial genomics and metagenomi

245 t ideal for drugs with short biological half-lives or small therapeutic windows.

246 Tuberculosis (TB) claims 1.5 million lives per year.

247 ects on their light absorption, thermal half-lives, photostationary states, fatigue, and quantum yiel

248 al economy and claimed more than 1.7 million lives, presenting an urgent global health crisis.

249 Initiatives, such as the Saving Young Lives programme, to train local medical staff from low-r

250 Branched PFOS isomers had average half-lives ranging from 1.05 to 1.26 y for different isomers.

251 er in neutral than in acidic soils with half-lives ranging from only 2 to >120 days.

252 impact on the economic aspects of patients' lives remains unknown.

253 ing RSMR would result in a greater number of lives saved (3592 vs 2161, P < 0.01) and require only 15

254 ence of car safety technologies, and (4) the lives saved and DALYs averted if all cars had these tech

255 Although the number of lives saved by immunotherapy mounts, only a relatively s

256 afest" hospitals and the potential number of lives saved through patient realignment determined.

257 Next, models were constructed with the Lives Saved Tool (LiST) using country-specific baseline

258 We used the Lives Saved Tool to estimate the additional maternal and

259 For this modelling study, we used the Lives Saved Tool to estimate the number of deaths that w

260 echnology and multitasking in their personal lives, school and the workplace, creating myriad challen

261 problems and maintaining social and personal lives, significant burden and stress can occur.

262 multiple cutoff criteria and predicted shelf-lives (SL(predicted)).

263 t people become parents during their working lives, STEM fields must do more to retain professionals

264 Modeling based on mRNA half-lives suggests that most degradation factors bind intact

265 prospective Tracking Adolescents' Individual Lives Survey cohort in the Netherlands with measurements

266 yields, and the extremely long thermal half-lives (tens to thousands of years) were maintained in mo

267 Tuberculosis claims more human lives than any other bacterial infectious disease and re

268 Tuberculosis claims more human lives than any other infectious disease.

269 Branched PFOS isomers had shorter half-lives than linear PFOS isomers.

270 experiments revealed RNAs with shorter half-lives than those reported after chemical inhibition of t

271 tless force for a world of longer, healthier lives, the 2030 Impact Goal is anchored in an understand

272 and why it evolves, leading to the saving of lives through more timely and geographically targeted in

273 The oncology nurse influence in saving lives through prevention and early detection of cancer i

274 and 65% of stillbirths, allowing 4.3 million lives to be saved annually by 2035.

275 ligands by the different ligand binding half-lives to the T cell receptor (TCR).

276 in ways that still dominate our professional lives today.

277 erdependent collaboration - scaled up to our lives together in an interdependent cultural group - thi

278 o both resulted in significantly longer half-lives (up to 50% longer).

279 wo orders of magnitude, and the thermal half-lives vary between milliseconds and hours.

280 During our everyday lives, we are confronted with a vast amount of informati

281 In our daily lives, we consume foods that have been transported, stor

282 From 87,941,718 analyzed lives, we identified 16,292,018 opioid prescriptions fil

283 Half-lives were also determined for two known metabolites and

284 RNAs expressed at low levels with short half-lives were enriched in the polysomes of upf1 mutants, in

285 Half-lives were estimated by assuming one compartment, first-

286 as depleted at 100 mum; however, oxygen half-lives were longer at 18 mW/cm(2) than at 30 mW/cm(2).

287 reduction of their respective mRNAs and half-lives were observed in GRTH-KI mice.

288 wo PARP1-mRNA targets we found that the half-lives were significantly decreased in PARP1-depleted cel

289 fords potent PYY analogs with >14 h rat half-lives, which are expected to translate into a human half

290 experiments in activated sludge to soil half-lives, which are obtained from much more work- and resou

291 It causes loss of human lives, which arise from infection and inflammation and l

292 Delayed images, up to 10 half-lives with (18)F-FDG, revealed biologic insight and supp

293 A general pattern of increasing half-lives with increasing chain length was observed.

294 Most invertebrates in the ocean begin their lives with planktonic larval phases that are critical fo

295 Sustaining longer lives with reduced periods of disability will require an

296 e has radically changed the structure of our lives, with devastating social and economic consequences

297 iming for illustrative purposes 1 million US lives, with results approximately scalable over a broad

298 s teeth from 43 children living their entire lives within 2 miles of the smelter were analyzed to und

299 rent countries, claiming more than 1 million lives worldwide.

300 IgG1 and IgG2 have similar half-lives, yet IgG2 displays lower foetal than maternal conc