ライフサイエンスコーパス: lordosis

1 ation to reinstate feminine sexual behavior (lordosis).

2 quantified as the copulatory stance known as lordosis.

3 for a significant proportion of variance in lordosis.

4 of the female rodent reproductive behavior, lordosis.

5 atosensory, not just hormonal, influences on lordosis.

6 al hormone treatments sufficient to activate lordosis.

7 eptors, which is expected in turn to promote lordosis.

8 oceptors also facilitates estrogen-dependent lordosis.

9 a role for MeApd GABA in the facilitation of lordosis.

10 ensatory mechanisms such as increased lumbar lordosis.

11 abnormally such as scoliosis, kyphosis, and lordosis.

12 avity of wedged lumbar vertebrae, known as a lordosis.

13 and eventually develop bowed legs and lumbar lordosis.

14 uct of his advanced age, osteoarthritis, and lordosis.

15 cell group crucial for estrogen induction of lordosis.

16 OR and induces the sexual receptive behavior lordosis.

17 hr amide reversed LPNY-induced inhibition of lordosis.

18 cated in alpha(1)-adrenergic facilitation of lordosis.

19 lieving estrogen inhibition and facilitating lordosis.

20 inea pigs displayed progesterone-facilitated lordosis (85.7% vs. 5.8%, respectively, p<0.05), there w

21 gulation of the female reproductive behavior lordosis, a behavior dependent upon the sequential activ

22 Genetic influences on lordosis, a mammalian social behavior, are amenable for

23 al beta isoform of the ER gene showed normal lordosis and courtship behaviors, extending in some case

24 a,5alpha-THP; 100 or 200ng/side)-facilitated lordosis and its enhancement by D1 (SKF38393; 100ng/side

25 ossessed a lower back consistent with lumbar lordosis and other adaptations to bipedalism, including

26 torso that are argued to have permitted both lordosis and pelvic stabilization during upright walking

27 In thoracolumbar/lumbar coronal asymmetry, lordosis and sagittal imbalance were the larger coeffici

28 measures of spinal sagittal shape (kyphosis, lordosis and sagittal imbalance, which is a measure of t

29 tures of spinal sagittal shape, particularly lordosis and sagittal imbalance.

30 parameters related to coronal asymmetry were lordosis and sagittal imbalance.

31 stent with the behavioral incompatibility of lordosis and ultrasound production and suggest that the

32 ion and time course of the lesion effects on lordosis and ultrasound production suggest that the VMN

33 and cervical vertebrae indicating pronounced lordosis, and Baastrup disease as a product of his advan

34 inhibited estrogen plus progesterone-induced lordosis, and the MOR-selective antagonist D-Phe-Cys-Tyr

35 into the medial preoptic nucleus attenuated lordosis, and their effects were blocked with the MOR an

36 ce the quality of the reproductive behavior, lordosis, and to reduce the EMG of lumbar back muscles i

37 29 +/- 7.04 mm, d = 1.03), and in the lumbar lordosis angle (males = 37.69 +/- 8.89 degrees vs. femal

38 orrelation of lumbar temperature with lumbar lordosis angle (r = - 0.50) and dorsal temperature with

39 (genital sniffing of females by male mice), lordosis (arched-back mating posture in female rats), co

40 wed a transient, but significant, decline in lordosis behavior 5 and 10 min after restraint.

41 aminobutyric acid (GABA) modulate female rat lordosis behavior and appear to interact in their contro

42 Therefore, NO regulation of lordosis behavior and gonadotropin release in female rat

43 in the VMN are involved in the modulation of lordosis behavior and lead to the suggestion that 5-HT2C

44 As expected, 8-OH-DPAT reduced lordosis behavior and muscimol attenuated this inhibitio

45 tion of 5-HT(2A/2C) receptors can facilitate lordosis behavior and that the VMN is one site at which

46 th EB showed significantly greater levels of lordosis behavior compared with OVX females treated with

47 ving 200 ng 8-OH-DPAT exhibited a decline in lordosis behavior following infusion.

48 E- and P-binding neurons important for lordosis behavior have been located within the ventromed

49 nucleus of the hypothalamus (VMN), inhibited lordosis behavior in all hormone-treated conditions.

50 alpha(1)-adrenoceptor antagonist prazosin on lordosis behavior in E(2)- and P-treated female rats.

51 itatory effects of alpha(1)-adrenoceptors on lordosis behavior in female rats, and previous exposure

52 sary for the expression of hormone-dependent lordosis behavior in female rats.

53 e protein kinase G inhibitor KT5823 inhibits lordosis behavior in hormone-treated female rats.

54 l (E(2)) and progesterone (P) facilitate rat lordosis behavior in part by regulating the expression o

55 st action at 5-HT(2A/2C) receptors increased lordosis behavior in rats with low sexual receptivity.

56 s of T3 showed significantly lower levels of lordosis behavior in response to estradiol benzoate (EB)

57 ) receptor antagonist, ketanserin, inhibited lordosis behavior in sexually receptive rats.

58 tor subtypes contribute to the modulation of lordosis behavior in the female rat.

59 onsistent with reports that GABA facilitates lordosis behavior in this hypothalamic structure.

60 e pulses could be reversed and still achieve lordosis behavior induction.

61 dence that the effects of 5-HT on female rat lordosis behavior involve the integrated activity of at

62 ) receptor-mediated inhibition of female rat lordosis behavior is also discussed.

63 onadotropin-releasing hormone release and of lordosis behavior of female rats.

64 tive to hormone-primed, ovariectomized rats, lordosis behavior of proestrous females was less affecte

65 th several reports that muscimol facilitates lordosis behavior of suboptimally hormonally primed fema

66 tion of estradiol, an estrogen necessary for lordosis behavior to occur, heightens this effect.

67 Lordosis behavior was examined following bilateral infus

68 tor interaction in the control of female rat lordosis behavior was examined.

69 le for VMN 5-HT3 receptors in the control of lordosis behavior was examined.

70 Estradiol-induced lordosis behavior was observed in response to a stud mal

71 Lordosis behavior was observed prior to VMN infusion, du

72 both routes of administration, inhibition of lordosis behavior was seen following treatment with the

73 In contrast, DZ facilitates lordosis behavior when infused into the midbrain central

74 8-OH-DPAT inhibited lordosis behavior within 15 min of the infusion and ever

75 e state: virgins display sexual receptivity (lordosis behavior), while lactating mothers attack.

76 olymerization with cytochalasin D attenuated lordosis behavior, indicating the importance of estradio

77 reduced the ability of 8-OH-DPAT to inhibit lordosis behavior, rats were preprimed with 10 microg EB

78 t was given progesterone and then tested for lordosis behavior, the induction of which requires the g

79 lamic ventromedial nucleus (VMN) facilitated lordosis behavior-inducing genomic actions of estrogen.

80 he effects of 5-HT2 receptor-active drugs on lordosis behavior.

81 A receptor antagonist, effectively inhibited lordosis behavior.

82 roduce two groups of rats differing in their lordosis behavior.

83 HT(2A/2C) receptor agonists could facilitate lordosis behavior.

84 ors mediating inhibition and facilitation of lordosis behavior.

85 effective in preventing DOI from increasing lordosis behavior.

86 y female sex behavior in laboratory animals, lordosis behavior.

87 rts a dual role in the control of female rat lordosis behavior.

88 le for VMN 5-HT3 receptors in the control of lordosis behavior.

89 tron producing the most consistent change in lordosis behavior.

90 cause, alone, 1500 ng mCPBG slightly reduced lordosis behavior.

91 tion to the role of 5HT in the regulation of lordosis behavior.

92 leus of the hypothalamus (VMN) to facilitate lordosis behavior.

93 oth sexes were gonadectomized and tested for lordosis behavior.

94 blood levels of progesterone, and eliminated lordosis behavior.

95 wild type females, CX43+/- mice had reduced lordosis behavior.

96 These cells are essential for lordosis behavior.

97 tors in the mediobasal hypothalamus inhibits lordosis behavior.

98 Muscimol alone also reduced lordosis behavior.

99 pylamino)tetralin (8-OH-DPAT), on female rat lordosis behavior.

100 altering the 5-HT(1A) receptor modulation of lordosis behavior.

101 e hypothalamus, these changes are needed for lordosis behavior.

102 knocked out show that ERalpha is crucial for lordosis behavior.

103 the ventromedial hypothalamus (VMN) depress lordosis but increase ultrasonic vocalization in female

104 vation of glutamate neurons had no effect on lordosis, but increased self-grooming.

105 ine D1 receptor stimulation, facilitation of lordosis by D1 receptor stimulation in estradiol-primed

106 the VMN blocked the subsequent induction of lordosis by D1-like agonists.

107 itation of one component of mating behavior, lordosis, by vaginal-cervical stimulation does not requi

108 groups for the following measured variables: lordosis C2-C7, anterior head translation, amplitudes of

109 phy, T2 hyperintensity, and loss of cervical lordosis, can be seen on neutral MRI as well, which subs

110 es not appear to be directly involved in the lordosis circuit, but appears to direct behavior away fr

111 Radiographic parameters include the cervical lordosis (CL), T1 slope, C2-C7 sagittal vertical axis (C

112 upports the proposed hierarchical network of lordosis control.

113 Sexual proceptivity and receptivity (lordosis) during the postpartum estrus were virtually el

114 atrophy, T2 hyperintensity, loss of cervical lordosis, enhancement of posterior epidural venous plexu

115 determine if either drug would attenuate the lordosis-facilitating effects of DOI.

116 sion of a membrane P receptor, 25-Dx, during lordosis facilitation.

117 (10 or 20 mg/kg) significantly reduced both lordosis frequency and quality and reduced (but not sign

118 MH2 was argued to demonstrate no appreciable lordosis ('hypolordosis') similar to Neandertals.

119 SA or P&BSA showed significant elevations in lordosis in 5 min.

120 d in 35.2% of patients, and loss of cervical lordosis in 58.8% of patients.

121 Present studies show that KT5823 attenuates lordosis in a dose-dependent manner when infused bilater

122 of the hypothalamus (VMH), OFQ/N facilitates lordosis in female rats through estrogen and progesteron

123 se results contrast with some recent work on lordosis in fossil hominins, where MH2 was argued to dem

124 ol displayed in AHAbd test and higher lumbar lordosis in individuals over 25 years seem to be probabl

125 ance the display of progesterone-facilitated lordosis in juvenile females, increase levels of hypotha

126 , 95% CI - 1.35 to - 0.08, P = 0.03), lumbar lordosis in participants over 25 years (Hedge's g 2.75,

127 enhanced display of progesterone-facilitated lordosis in prepubertal guinea pigs following MPOA lesio

128 on coronal asymmetry for males and females, lordosis increased with coronal asymmetry in females onl

129 sm by which acute E exposure facilitates the lordosis-inducing genomic actions of estrogens.

130 tions in the hypothalamus can potentiate its lordosis-inducing genomic actions on behavior and may be

131 aspects of mating, including facilitation of lordosis, induction of sexual receptivity, abbreviation

132 le both estrogen and progesterone reduce the lordosis-inhibiting effect of 8-OH-DPAT, the mechanisms

133 subchronically treated with fluoxetine, the lordosis-inhibiting effect of an acute injection with fl

134 DOI attenuated the lordosis-inhibiting effect of ketanserin, but ketanserin

135 g quipazine or TFMPP were protected from the lordosis-inhibiting effects of 8-OH-DPAT, alone.

136 gesterone, prepriming with EB attenuated the lordosis-inhibiting effects of systemic treatment with 8

137 The lordosis-inhibiting effects of the 5-HT1A receptor agoni

138 /M)>/=0.5 were used to examine the potential lordosis-inhibiting effects of the 5-HT2A receptor antag

139 a new pelvic reconstruction to infer lumbar lordosis, interarticulation of lower lumbar (L4-S1) and

140 The neural circuit for lordosis involves a supraspinal loop, which is controlle

141 mechanism through which estrogen facilitates lordosis is by remodeling synaptic connectivity within t

142 e the EMG of lumbar back muscles involved in lordosis is exerted through a reticulospinal pathway wit

143 Duration and intensity of lordosis is mediated by actions of the progesterone (P)

144 ong evidence that dopaminergic modulation of lordosis is mediated by the novel D5 dopamine receptor.

145 Lordosis is regulated by estrogen and progesterone (P4)

146 subtype mediating E(2) and P facilitation of lordosis is the alpha(1)-adrenoceptor.

147 luded anterolisthesis, osteophytic spurring, lordosis, kyphosis, and nerve root impingement.

148 and radiological parameters (C7-SVA; lumbar lordosis, LL; the difference between pelvic incidence an

149 rameters-pelvic incidence (PI), lower lumbar lordosis (LL4-S), and spinal 3D length (S3DL)-significan

150 about the local VMH microcircuitry governing lordosis nor how estrogen alters synaptic connectivity w

151 enous P (200 microg) significantly increased lordosis of all mice within 10 min of P, but vehicle inf

152 uced plasma 3alpha,5alpha-THP and attenuated lordosis of all mice.

153 RU38486, a PR antagonist, attenuated lordosis of C57 and C57x129, but not PRKO, mice; epostan

154 alpha-ol-20-one (3alpha,5alpha-THP) enhanced lordosis of ovariectomized, sexually experienced C57BL/6

155 oxysteroid oxidoreduced product, facilitates lordosis of rodents in part via agonist-like actions at

156 We have found that progestogen-facilitated lordosis of rodents is enhanced by activation of dopamin

157 vived and developed progressive dwarfism and lordosis of the cervical spine.

158 metabolites' effects on sexual receptivity (lordosis) of mice was examined.

159 , compared with that seen in mice with lower lordosis on initial mating.

160 For sexually naive mice, greater lordosis on initial sexual experience corresponded to gr

161 ced neck deflection which increased cervical lordosis or kyphosis by 4-5 degrees to 11 degrees , depe

162 for the display of progesterone-facilitated lordosis or perfused, and their hypothalamic tissue proc

163 ount and duration and reduced the latency of lordosis, over that seen with vehicle infusion, in PRKO

164 fference between pelvic incidence and lumbar lordosis, PI-LL; pelvic tilt, PT) were assessed.

165 anterior head translation distance, cervical lordosis (posterior bodies of C2-C7), central somatosens

166 ts sensorimotor integration of the analogous lordosis posture displayed by sexually receptive female

167 gment of the motor pathway that produces the lordosis posture, the hallmark of female rat sexual beha

168 The lordosis quotient (LQ) was measured following either pho

169 A typical sex difference in lordosis quotient (LQ) was observed and neonatal RU-486

170 VMHVL resulted in a significant reduction in lordosis quotient compared to control (reverse sense) OD

171 midbrain central gray infusions of DZ on the lordosis quotient.

172 Receptivity (lordosis quotients and ratings) and proceptivity (dartin

173 etween intromissions and ejaculation, higher lordosis quotients and ratings, more pacing of their sex

174 us oxytocin infused controls, as measured by lordosis quotients and receptivity scores, at 40, and 90

175 howed reduced intromission-like behavior and lordosis quotients compared with vehicle and scrambled c

176 Lordosis quotients were reduced about 50% in nonandrogen

177 The simplest hypothesis was that lordosis quotients would be significantly reduced as a r

178 al role of hypothalamic opioid expression in lordosis reflex 16-mer oligodeoxynucleotide (ODN) direct

179 ng the neuraxis previously implicated in the lordosis reflex are indeed serially connected.

180 The lordosis reflex is a hormone-dependent behavior displaye

181 mount (L/M) ratio and in the quality of the lordosis reflex with 500 ng tropisetron producing the mo

182 receptor agonist altered the quality of the lordosis reflex.

183 tal development of this limbic-hypothalamic, lordosis regulating circuit, and to determine the age at

184 expression in the adult limbic-hypothalamic lordosis regulating circuit, which are not functional be

185 d may be subject to estrogenic influences in lordosis-relevant neurons in the ventrolateral subdivisi

186 It is suggested that muscimol may enhance lordosis responding in suboptimally hormonally primed ra

187 However, both drugs limited the duration of lordosis responding initiated by DOI.

188 ,907 in reducing the DOI-induced increase in lordosis responding.

189 -HT1A receptor antagonist did not facilitate lordosis responding.

190 In Experiment 2, SP diminished the lordosis response as it did in Experiment 1.

191 exposure to SP for ten weeks attenuated the lordosis response following sequential treatment with es

192 The expression of the lordosis response is modulated by OT action in the ventr

193 1) alpha(1)-adrenoceptors in the HYP enhance lordosis responses by activating the nitric oxide (NO)-c

194 h past results, unilateral lesions disrupted lordosis responses to contralateral flank stimulation.

195 ale guinea pigs rarely display adult-typical lordosis responses to ovarian steroid hormones until 40-

196 ng-term spinal problems, including kyphosis, lordosis, scoliosis, and hypoplasia.

197 xhibits a pelvic incidence (and hence lumbar lordosis) similar to modern humans, articulation of lumb

198 The lordosis stabilizes the upper body over the lower limbs

199 he arcuate nucleus or preoptic area, induced lordosis, suggesting the functional presence of D5 dopam

200 m social interactions.SIGNIFICANCE STATEMENT Lordosis, the measure of female sexual receptivity, is a

201 Lordosis, the measure of female sexual receptivity, is o

202 wild type mice suggest that P may facilitate lordosis through actions at substrates other than intrac

203 on-traditional actions in the VTA to enhance lordosis through D1 and/or GABA(A) include activity of P

204 Females with a lordosis to mount (L/M) ratio < 0.5 were used to test th

205 ere was a dose-dependent decline in both the lordosis to mount (L/M) ratio and in the quality of the

206 Tropisetron reduced the lordosis to mount (L/M) ratio in every animal investigat

207 Rats with a lordosis to mount ratio (L/M)>/=0.5 were used to examine

208 ha-THP-, SKF38393-, and muscimol-facilitated lordosis was attenuated by infusions of the PLC inhibito

209 Progestin facilitation of lordosis was correlated with a reduction of estrogen-ind

210 lses (15 min to 2 h duration, and 5 h apart) lordosis was induced.

211 ular progestin receptors (PRs) to facilitate lordosis was investigated in PR knockout (PRKO) mice, PR

212 t the delayed post-EB timepoint, significant lordosis was noted and the duration of intra-Acb DAMGO-d

213 Lordosis was observed in response to solicitous males in

214 In thoracic coronal asymmetry, whilst lordosis was predominant, kyphosis played more of a role

215 les raised on a diet high in phytoestrogens, lordosis was reduced in comparison with females of both

216 Cervical lordosis was significantly improved postoperatively (- 1

217 ) activation, the steroid-dependent behavior lordosis was used in estrogen-primed ovariectomized Spra

218 sthetics, which would block E's induction of lordosis when administered at the time of estrogen appli

219 ed to bovine serum albumin (P:BSA) increased lordosis when applied bilaterally to both the VMH and VT

220 rdosis with i.v. P infusion and increases in lordosis when P's effects are relegated to the membrane

221 of GABAergic neurons in the MeApd inhibited lordosis, while photoactivation of glutamate neurons had

222 The rapid facilitation of lordosis with i.v. P infusion and increases in lordosis