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1 bitor of the Akt-beta-catenin interaction at low doses.
2 ials at high doses and biofilm inhibitors at low doses.
3 in the mode of action of this insecticide at low doses.
4 ketamine were superior to active placebo; a low dose (0.1 mg/kg) was significant only prior to adjus
5 the effects of naloxone-methiodide at a very low dose (0.2 mg/kg; at which naloxone was undetectable
6 titumor immunity amplification with an ultra-low dose (0.25 mug kg(-1) ), which is several hundred ti
7 Systemic administration of nilotinib at a low dose (0.5 mg/kg/day, i.p.) in tumor-bearing mice not
8 World Health Organization recommended single low-dose (0.25mg/kg) primaquine (PQ) in combination with
9 SV-NS1-based vaccine prevented deaths from a low dose (10(3) PFU) challenge, though they experienced
10 ASFV-G-DeltaI177L confers protection even at low doses (10(2) HAD(50)) and remains completely attenua
13 one-HCl, naloxone-methiodide at a relatively low dose (2 mg/kg) fully blocked heroin-induced decrease
16 he infection for 28 days, in an experimental low-dose (300 colony-forming units) intradermal model of
17 7 participants who received the ChAd155-RSV low dose, 31 who received the ChAd155-RSV high dose, 19
21 el RNA-Seq data to understand the effects of low-dose (56)Fe ion irradiation on the formation of hepa
22 In contrast, subcutaneous administration of low-dose 5A7 (0.08-0.16 mg/kg) every 3 days gradually lo
23 atio) measures were derived from noncontrast low-dose abdominal CT scans in a generally healthy asymp
24 erfaces and epitaxial growth are revealed by low-dose aberration-corrected high-resolution transmissi
28 rimary lung, breast and oesophageal cancers, low-dose adjuvant epigenetic therapy disrupts the premet
39 interval (CI) 66%-89%) accurate diagnosis in low-dose and 80% (95% CI 67%-90%) in standard CT by prim
41 al received a half dose as their first dose (low dose) and a standard dose as their second dose (LD/S
42 th three thirds (standard dose), two thirds (low dose), and one third (very low dose) of the injected
43 4 for the standard dose, 3.4 +/- 0.7 for the low dose, and 1.9 +/- 0.4 for the very low dose; all P <
44 d by 0.94%, 2.75%, and 4.24% in the placebo, low-dose, and high-dose groups, respectively (P =.032 fo
45 he standard dose; 95%, 81%, and 90% with the low dose; and 71%, 76%, and 59% with the very low dose,
48 rials demonstrated that chemoprophylaxis, or low-dose anticoagulation, prevents VTE in selected medic
50 ion is needed about the long-term effects of low-dose aspirin (<=160 mg) on incident hepatocellular c
53 4-40 years were randomly assigned to receive low-dose aspirin (5990 women) or placebo (5986 women).
54 , double-masked, placebo-controlled trial of low-dose aspirin (81 mg daily) initiated between 6 weeks
55 lyunsaturated fatty acids (omega-3 PUFA) and low-dose aspirin (ASA) have been proposed as a host modu
57 concerned, all 3 of our patients were taking low-dose aspirin and/or clopidogrel as secondary cardiov
59 from low-income and middle-income countries, low-dose aspirin initiated between 6 weeks and 0 days of
62 revention Guidelines recommended considering low-dose aspirin therapy only among adults 40 to 70 year
64 th chronic viral hepatitis in Sweden, use of low-dose aspirin was associated with a significantly low
66 ilator alone (Protocol 1: ACh or Protocol 2: low dose ATP); (ii) mild handgrip exercise (5% maximum v
68 determined whether the absence of CAC, using low-dose attenuation correction CT obtained during the P
74 sGMA-based dental materials and that chronic low-dose BPA exposure may adversely affect child health,
77 tC neurons attenuated rate depression at the low dose, but had no effect on rate following high doses
78 uced in mice that are not only protective at low doses, but that we extensively test to determine the
79 ows that oral exposure to EE, even at a very low dose, can exacerbate azotemia, increase clinical mar
80 validity and limitations of the concept that low dose cardiovascular polypills, already in large scal
81 of COVID-19 infection were studied by using low-dose chest CT and real-time reverse transcription po
83 utional neural network trained with (a) 1181 low-dose chest CT examinations (baseline), (b) a small s
85 lysis of lung involvement on submillisievert low-dose chest CT outperformed conventional visual analy
86 test in mice lacking GLAST the effects of a low-dose cisplatin known not to cause any detectable cha
87 (I/R), aristolochic acid, and repeated acute low-dose cisplatin was also alleviated in PT-DsbA-L-KO m
89 s) (n = 21), or an investigational arm using low-dose CNI plus costimulation blockade (belatacept) wi
95 mized trials regarding whether volume-based, low-dose computed tomographic (CT) screening can reduce
96 rial (NLST) demonstrated that screening with low-dose computed tomography (LDCT) is associated with a
98 04), a randomized controlled trial comparing low-dose computed tomography (LDCT; n = 26,722) with che
99 ent annual review since 1990, chest X-ray or low-dose computed tomography scan, and outcome linkage t
100 rticles and HIV-1 virus-like particles under low-dose conditions (5.7 e/ angstrom(2)) and heterogeneo
101 m were enrolled to undergo both standard and low-dose contrast enhanced CT scans, which were categori
102 hat treatment of C57Bl/6J male breeders with low-dose corticosterone (CORT) for 28 days prior to mati
103 tients (group 1) were acquired with an ultra-low dose CT (32-MDCT, 130 kV, tin filter and iterative r
104 Two large randomized controlled trials of low-dose CT (LDCT)-based lung cancer screening in high-r
106 d to the costal pleura (CP-NCNs) at baseline low-dose CT and to identify key features of benignity.
114 trospective review was performed of baseline low-dose CT scans obtained in 8730 participants in the M
115 e mid to late 1990s, however, indicates that low-dose CT screening of high-risk patients enables dete
116 Diagnostic accuracy of contrast enhanced low-dose CT was not inferior to standard CT in diagnosin
119 combination with hypomethylating agents and low-dose cytarabine in older adults for whom chemotherap
121 clax combined with hypomethylating agents or low-dose cytarabine represents an important new therapy
123 bone and cemental regeneration while local, low dose delivery did not heal periodontal osseous defec
124 n and symptoms of heart failure treated with low-dose digoxin or bisoprolol, there was no statistical
126 dard dose of epinephrine to placebo, high or low dose epinephrine, any other vasopressor alone or in
128 quine estrogens and the beneficial effect of low-dose estrogen treatment of patients with acquired ar
129 sed both the locomotor-activating effects of low dose ethanol and the sedative-hypnotic effects of a
130 from SPLAT flowable matrix with and without low-dose ethanol dispensers for manipulation of ambrosia
131 erbenone dispensers (SPLAT) co-deployed with low-dose ethanol dispensers than when treated with verbe
133 udy was to describe the effects of combining low-dose EVL and CNIs in maintenance immunosuppression r
134 MARV glycoprotein (GP) 20-30 minutes after a low dose exposure to the most pathogenic variant of MARV
135 To reduce aerosol transmissions, the use of low dose far-UVC lighting to disinfect in-room air has b
136 er (7 g/d) or control in Trial 1 (n = 25) or low-dose fiber (3 g/d) or control in Trial 2 (n = 25), w
137 ol group) and in participants who received a low dose followed by a standard dose, efficacy was 90.0%
139 nanoscale crystallographic analysis and the low-dose formation of multiple diffraction contrast imag
142 ed place preference (CPP) and the effects of low dose guanfacine on BNST activity and stress-induced
145 TX, USA), with refractory agitation, despite low-dose haloperidol, were randomly assigned to receive
149 with COVID-19 and acute respiratory failure, low-dose hydrocortisone, compared with placebo, did not
151 nsulin bolus-induced hypoglycemia test and a low-dose hyperinsulinemic-hypoglycemic clamp procedure.
154 tep 2 (mild persistent asthma), either daily low-dose ICS plus as-needed SABA therapy or as-needed co
155 py for moderate persistent asthma in step 3 (low-dose ICS-formoterol therapy) and step 4 (medium-dose
156 patients entered a 1-month run-in period on low-dose ICS/LABA budesonide/formoterol (BUD/F) 200/6 on
157 In contrast, alveolospheres pretreated with low-dose IFNs show a reduction in viral replication, sug
162 days (PND) 14 to 21, followed by ad libitum, low-dose individual ABX or ABX cocktail in the drinking
163 by the organism comprise compounds that, at low doses, induce stress resistance mechanisms, includin
165 xperimentally tested the model by inhibiting low dose infection with the drug tenofovir, which interf
166 ildren with asthma aged 6 to 16 years taking low-dose inhaled corticosteroids and with serum 25-hydro
170 c time >=4 to 6 h, adjunctive treatment with low-dose intracoronary alteplase during primary percutan
171 d safety of a therapeutic strategy involving low-dose intracoronary alteplase infused early after cor
174 is reactions were amenable to treatment with low-dose intravenous adrenaline, with no reported advers
175 le is known about how continuous exposure to low dose ionising radiation affects normal cells and org
177 ences showing that genotoxic injury, such as low dose irradiation, may promote an IGFBP-4 release in
180 ce hemodialysis for ESKD to a high-dose or a low-dose IV iron regimen, with a primary composite outco
189 mans, demonstrate that the administration of low-dose ketamine does not impair tolerance to simulated
192 thesis in both image and sinogram space from low-dose (LD) PET images and sinograms without sacrifici
193 received 1 or 2 intramuscular injections of low-dose (LD; 5 x 1010 vector particles) or high-dose (H
194 kg feed weight) or BPA (5 mg/kg feed weight, low dose- LD or 50 mg/kg, upper dose-UD), and dams were
195 cures in 100% of the test animals with very low dose levels (300 nmol/kg) following a convenient onc
198 on, the use of systemically-delivered versus low dose locally-delivered Scl-Ab via poly(lactic-co-gly
199 ial-type thrombus propagation at exceedingly low doses (<2 ug/kg, IV), yet without substantial system
202 ) and other forms of inflammatory arthritis, low-dose methotrexate therapy remains the gold standard
205 ovel OPV2-c1, 122 (93% [87-97]) of 131 after low-dose novel OPV2-c1, 138 (95% [90-98]) of 146 after h
207 ed higher mRNA delivery potency in vivo at a low dose of 0.1 mg kg(-1) when formulated with a PBD-lip
210 ihood of severe reactions and reactions to a low dose of allergen in individual patients with PA.
213 n vestibular hair cells, administration of a low dose of DT caused profound SNHL without vestibular d
215 tment of SARS-CoV-2-infected hamsters with a low dose of favipiravir or hydroxychloroquine with(out)
216 an clock in the suprachiasmatic nucleus to a low dose of morphine, and showed the bidirectional effec
218 ed survival times in mice co-infected with a low dose of T. muris on d 105 after CNS prion infection
220 ple mouse models of murine tumours, a single low dose of the STING agonist led to tumour regression a
222 ta were confirmed in rhesus macaques where a low dose of TMV-NPNAx5 elicited Abs that persisted at fu
223 g a higher dose may yet be needed, while the low dose of TS-134 showed evidence of symptom reduction
226 this was also the case for BMDMs exposed to low doses of BTK inhibitors such as ibrutinib and for mo
229 used the zebrafish model to investigate how low doses of DomA affect the developing nervous system,
232 Many studies have demonstrated impacts of low doses of insecticides on insect behavior, but have n
235 at can be partially rescued to reduce CIN by low doses of paclitaxel and nucleoside supplementation,
237 allenged intravaginally with repeated weekly low doses of SIV(mac251) administered 3 h after applicat
238 ll-specific R26-mTmG reporter mice, in which low doses of tamoxifen allowed labeling of single-cell p
239 n indication for anticoagulation, the use of low doses of the factor Xa inhibitor, rivaroxaban, has s
241 se curve" with increasing cAMP production at low doses of TSH and decreased cAMP production at high d
242 immunosuppressed hamsters are susceptible to low doses of virus and develop more severe and prolonged
245 ) and 11 (15.7%) of the CsA CE high-dose and low-dose patients, respectively, most commonly instillat
246 ations in the areas of image reconstruction, low-dose PET, disease detection, and models used for dia
247 f 6 swine were treated with pulsed fields at low dose (PF(LD)) and high dose (PF(HD)) and followed fo
252 into the long-term effects of environmental low dose radiation on fish ovaries development, a high-t
255 therapy seeds, the VADER can provide varying low dose rate irradiations at dose rates of 0.1 to 1.2 G
257 e large biological uncertainties of chronic (low-dose rate) heavy-ion exposures and the validation of
258 l beam radiation therapy (EBRT; n = 261), or low-dose-rate brachytherapy (n = 87) for men with favora
260 aying within current regulatory dose limits, low-dose-rate far-UVC exposure can potentially safely pr
261 o cleanup workers and/or evacuees exposed to low-dose-rate radiation after the 1986 Chornobyl (Cherno
264 ction and developed a therapeutic regimen of low-dose recombinant human interleukin-2 (IL-2) combined
265 regimen of 3.7 MBq/kg, images from simulated low-dose regimens (1.9-0.41 MBq/kg) were evaluated using
269 er, scores of PET-only images were lower for low-dose scans, with a 12% reduction for 1/3-dose images
271 sublayer surfaces of MIL-101 is reported by low-dose spherical aberration-corrected high-resolution
274 B transcription factor activation induced by low-dose streptozocin (LD-STZ) treatment in the immunoco
276 ells mitigated hyperglycemia in the multiple low-dose streptozotocin model of diabetes, demonstrating
277 amined mice rendered hyperglycemic following low-dose streptozotocin prior to increasing cardiomyocyt
281 Combination treatment with cibinetide and low-dose tacrolimus significantly improved long-term gra
284 stigate the long-term efficacy and safety of low-dose TG therapy in IBD patients failing AZA and MP.
285 2 bioavailability is dose dependent and at a low dose that approximates the normal daily requirement
288 Ds for mediating rapid red cell clearance at low doses, to enable effective, inexpensive prophylaxis.
290 thors sought to determine whether adjunctive low-dose transdermal testosterone improves depression sy
291 base data to describe trends in zolpidem and low-dose trazodone dispensing among adults with employer
294 uman disease, we infected mice with an ultra-low dose (ULD) of between 1-3 founding bacteria, reflect
296 [QID, high-dose] or CsA CE twice daily [BID, low-dose] + vehicle BID) and vehicle patients were alloc
297 this study, male use of pain medications at low doses was not notably associated with fecundability.
300 ustoluminogens (AIE-Au) to achieve efficient low-dose X-ray-induced photodynamic therapy (X-PDT) with