ライフサイエンスコーパス: low-protein

1 ] carbohydrate, and 0.4 g/[kg/h] lipid) or a low protein (0.4 g/[kg/h] protein, 2.2 g/[kg/h] carbohyd

2 Canada goose goslings fed low-protein (10%) diets were on average 44% lighter in b

3 diets containing 5% of energy from protein (low protein), 15% (normal protein), or 25% (high protein

4 state (0-3 h), who were fed half-hourly with low-protein (2% of energy, 3-6 h) and isoenergetic highe

5 Volunteers underwent 6 wk of 150% low-protein (2%) overfeeding followed by another wk of w

6 or 24 h each and included the following: (1) low protein (3%), (2) standard (50% carbohydrate, 20% pr

7 ly increased by threefold only after the two low-protein (3%) overfeeding diets, one high in carbohyd

8 A low-protein (6.25 g) mixed macronutrient beverage can be

9 dams fed either a control (20% protein) or a low protein (8% protein) isocaloric diet.

10 n (7.21 +/- 3.08 MJ/d) condition than in the low-protein (9.33 +/- 3.52 MJ/d) and normal-protein (9.6

11 had only a single peptide match, indicating low protein abundance and/or false-positive peptide matc

12 in thousands of individuals with high versus low protein abundance.

13 cient to target firefly luciferase (LUC) for low protein accumulation equivalent to that observed pre

14 n the necessary cis-acting element to confer low protein accumulation onto LUC, while a fusion protei

15 ts original host, R. eutropha, revealed only low protein amounts.

16 oth loss and the proportion of patients with low protein and caloric intake (P = 0.02 and 0.01, respe

17 d pressure parameters in male offspring from low protein and control-fed dams measured simultaneously

18 with low N content and artificial diets with low protein and high carbohydrate content.

19 g mainly of poorly bioavailable lignin, with low protein and lipid content, the carbohydrates from fa

20 balance to Deltanitrogen intake between the low-protein and higher-protein periods, was 0.68 +/- 0.0

21 The benefits of low protein (and phosphorus) diets include the ameliorat

22 Low-protein (and phosphorus) diets can also ameliorate u

23 r metabolic diseases who were treated with a low-protein, and consequently, low-lactose diet.

24 blood pressure and heart rate in control and low protein animals, ruling out an effect of enhanced pr

25 onitis, upper gastrointestinal bleeding, and low-protein ascites with associated poor liver function.

26 This suggests that low protein availability in fruits influences current le

27 id not inhibit the P450 3A4 isozyme, and had low protein binding (18.22% for 23) and a desirable log

28 Low protein binding (21%), large volume of distribution

29 ife of 5-7 h in three species and moderately low protein binding in both mouse (69%) and human (63%)

30 microbiological potency, low clearance, and low protein binding that can result in lower efficacious

31 ny favorable pharmacological traits, such as low protein binding, minimal human serum effect on anti-

32 was discovered for designing molecules with low protein binding.

33 ith high dependence on tubular secretion but low protein-binding affinity.

34 sually involves efficient manufacturing, but low protein bioavailability resulting in higher doses co

35 Persistently low protein C levels are related to poor prognosis.

36 Low protein C levels were associated with prolongation o

37 High thrombomodulin and low protein C levels were significantly associated with

38 ociated with high soluble thrombomodulin and low protein C levels.

39 ta demonstrate that C. parvum transcripts of low protein-coding potential are selectively delivered i

40 dentified a panel of RNA transcripts of very low protein-coding potential in C. parvum.

41 The low protein-coding potential of meRNAs suggests that man

42 ntransparent samples, to use samples of very low protein concentration (< or = 0.3 mg/ml), and to stu

43 le-resonance assignment strategy tailored to low protein concentration (0.2 mM) and poor chemical shi

44 Folding of equine cytochrome c at a low protein concentration (26 microM) eliminated a slow

45 The first occurs at low protein concentration and is characterized by an inc

46 presented that facilitates NMR studies at a low protein concentration of approximately 20 micoM.

47 the site-specific torsional relaxation at a low protein concentration under physiological conditions

48 For low protein concentration, no direct method is currently

49 At low protein concentration, the NBDs display an initial s

50 ngle stable complex with the gRNA gA6[14] at low protein concentration, while at higher protein conce

51 degradation rate compared to those formed at low protein concentration.

52 neutral pH reversibility is observed only at low protein concentrations (<0.5 mg/ml).

53 ains its structure and function at extremely low protein concentrations (<10(-)12 M).

54 nanoparticles conjugated with antibodies at low protein concentrations (<40 mug/mL) display self-ass

55 and (15)N-{(1)H} NOE data were collected at low protein concentrations (<or=100 microM) and at two f

56 zing system, especially in studies done with low protein concentrations (0.1 microM), and at elevated

57 ta protein fibrils that formed at relatively low protein concentrations and exhibited remarkably high

58 d of NF-LH transition to an isotropic gel at low protein concentrations as a function of increasing m

59 Low protein concentrations in these experiments prevente

60 A lag phase at low protein concentrations indicates that fibril formati

61 Protection at low protein concentrations is more pronounced and more e

62 unlabelled protein, it is not limited to the low protein concentrations normally required for single-

63 At low protein concentrations the structural rearrangements

64 switch from slow two-state-like exchange at low protein concentrations to fast exchange at higher, p

65 41 +/- 3 ns when measured at low proton and low protein concentrations to minimize protein aggregati

66 The fluorescence enhancement at low protein concentrations was buffer-dependent and requ

67 Dimerization constants calculated at low protein concentrations were 265, 750, 1212, and 7879

68 ibril formation is accelerated at relatively low protein concentrations, and the ability to seed the

69 At low protein concentrations, ATP promotes dimerization of

70 cular autoreduction process is implicated at low protein concentrations, but oligomerization decrease

71 ects with origin DNA and ssDNA especially at low protein concentrations, but only half were defective

72 d with Ni2+ and Cu2+ binding to H144*UreE at low protein concentrations, consistent with binding to s

73 uring static light scattering experiments at low protein concentrations, frequently the protein is as

74 The first phase, occurring at low protein concentrations, involves both electrostatic

75 s at high protein concentrations, whereas at low protein concentrations, it dissociates into dimers t

76 By contrast, REGbetaDeltai exhibited, at low protein concentrations, reduced proteasome activatio

77 s at high protein concentrations, whereas at low protein concentrations, they formed dimers, as did S

78 high protein concentrations and monomers at low protein concentrations.

79 nstants, and for performing experiments with low protein concentrations.

80 ingle-stranded DNA and origin DNA binding at low protein concentrations.

81 rmal single-stranded DNA binding activity at low protein concentrations.

82 inge model for noncooperative HMG binding at low protein concentrations.

83 lding is reversible and two-state for EP3 at low protein concentrations.

84 his same Bcd domain plays a positive role at low protein concentrations.

85 lysis of MIF after chemical cross-linking at low protein concentrations.

86 e-molecule screening in human serum at ultra-low protein concentrations.

87 At relatively low-protein concentrations, XPA formed a complex with DN

88 terleukin (IL)-8 was selectively released at low-protein concentrations.

89 -based reporter displacement assay with very low protein consumption was developed to enable the larg

90 ddition of amaranth flour, with a relatively low protein content (16.45%), did not mitigate acrylamid

91 , it is shown that they are small cells with low protein content suggestive of G0.

92 omposed of neutral and acidic sugars, with a low protein content.

93 with 79% protein and a starchy product with low protein content.

94 DDGS extracts had relatively low protein contents (14-44.9%, w/w), regardless of the

95 sponse to androgen exposure, were grown in a low protein-defined media under androgen-stimulated (A+)

96 otein aggregates have so far been limited to low protein densities in either vesicular or bilayer mor

97 are not pairwise additive, for sufficiently low protein density, thermodynamic properties depend onl

98 Patients were prescribed a very low protein diet (0.3 g/kg) plus supplemental essential

99 - 3.9 micromol kg-1 h-1, HP + W) but not the low protein diet (51.1 +/- 5.9 micromol kg-1 h-1, LP + G

100 protein diet (18% casein; NPD) or isocaloric low protein diet (9% casein; LPD) restricted to one ovul

101 We studied maternal low protein diet (LPD) during pregnancy/lactation in mic

102 Maternal low protein diet (LPD) fed during only the preimplantati

103 ein diet (NPD; 18% protein) or an isocaloric low protein diet (LPD; 9% protein) for a minimum of 7 we

104 Low protein diet and sodium or glycerol phenylbutyrate,

105 The impaired NO release in the MA of low protein diet dams was not accompanied by reduced eNO

106 We have shown maternal low protein diet exclusively during mouse preimplantatio

107 Primary osteoblasts from low protein diet fed mice showed decreased in vitro bone

108 h the significance of a sup-optimal paternal low protein diet for offspring vascular homeostasis and

109 oduced significantly less weight gain in the low protein diet group (3.16 kg; 95% CI, 1.88-4.44 kg) c

110 A low protein diet had minimal effects on paternal cardiov

111 enzyme activity were programmed by paternal low protein diet in a sperm and/or seminal plasma specif

112 The effect of maternal low protein diet in pregnancy on the function of offspri

113 n used to model the effects of exposure to a low protein diet in utero on adult blood pressure.

114 With the low protein diet leucine oxidation rates during feeding

115 Paternal low protein diet modified F1 male offspring testicular e

116 Paternal low protein diet modified F1 neonatal and adult offsprin

117 ation analyses and studied angiogenesis in a low protein diet rat model of IUGR.

118 In maternal low protein diet rat models of programming, administrati

119 However, dams fed the low protein diet showed extensive bone loss by the end o

120 after infection, with those on the high fat/low protein diet showing 30% survival at 8 days, vs. alm

121 f the total visceral CO2 production during a low protein diet, this increase did not compensate entir

122 idney development and function by a maternal low protein diet.

123 did not increase during overfeeding with the low protein diet.

124 s affecting the urea cycle while consuming a low protein diet.

125 s were instructed and their adherence to the low-protein diet (0.6 g/kg of body weight per day) was e

126 of ketoanalogue-supplemented vegetarian very low-protein diet (KD) compared with conventional low-pro

127 we revealed that newborns of dams exposed to low-protein diet (LP0.5) throughout pregnancy exhibited

128 NPY-Y2R system is also activated by maternal low-protein diet (LPD) and linked to obesity in offsprin

129 protein diet (KD) compared with conventional low-protein diet (LPD).

130 ng sheep were fed either a control (n=15) or low-protein diet (n=16, 17 vs. 8.7 g crude protein/MJ me

131 diet plus resistance training (n = 14) or a low-protein diet alone (n = 12) for 12 weeks.

132 her, these findings indicate that a maternal low-protein diet alters microRNA and mTOR expression in

133 ary calcium decreased significantly with the low-protein diet and increased significantly with the hi

134 r time can be assessed by 24-h overfeeding a low-protein diet and measurements of plasma FGF21 concen

135 to be effective against the catabolism of a low-protein diet and uremia in patients with renal failu

136 ion of renal disease in patients receiving a low-protein diet compared with patients receiving a usua

137 n participants randomly assigned to the very-low-protein diet compared with the low-protein diet.

138 nd by day 14 1.6-2.7 times higher during the low-protein diet compared with the medium-protein diet.

139 etween participants randomly assigned to the low-protein diet compared with the moderate-protein diet

140 In contrast, offspring of a low-protein diet displayed no deficits in operant learni

141 this issue of Molecular Cell that a paternal low-protein diet elevates ROS in the testicular germ cel

142 Offspring of males fed a low-protein diet exhibited elevated hepatic expression o

143 In the low-protein diet group whose excess energy was fat, the

144 SleepEE was unchanged by overfeeding in the low-protein diet group, and baseline surface area predic

145 dividuals with a blunted FGF21 response to a low-protein diet have a thrifty metabolism and are at ri

146 tudies demonstrated that in mouse dams fed a low-protein diet hepatic expression of FOXA2 and FOXA3 m

147 hancing autophagy by exposure to a prolonged low-protein diet improved cardiac function in Python mic

148 e reported previously that rats exposed to a low-protein diet in utero and postnatal catch-up growth

149 usly, we demonstrated that rats exposed to a low-protein diet in utero that underwent postnatal catch

150 we hypothesized that exposure to a maternal low-protein diet increases glomerular Ang II AT1 recepto

151 promoted impulsivity, whereas exposure to a low-protein diet led to marked inattention.

152 of support for protein leverage effects on a low-protein diet may stem from the fact that protein int

153 tary manipulations in the daughters in a rat low-protein diet model.

154 They were randomly assigned to a low-protein diet plus resistance training (n = 14) or a

155 five studies of nondiabetic renal disease, a low-protein diet significantly reduced the risk for rena

156 es of insulin-dependent diabetes mellitus, a low-protein diet significantly slowed the increase in ur

157 hase protein intake was 13% higher after the low-protein diet than after the high-protein diet (253 +

158 Fractional calcium absorption after the low-protein diet was 0.19+/-0.03, which was significantl

159 ion model, in which animals are exposed to a low-protein diet while in utero and then are cross-foste

160 In addition, after the low-protein diet, food preferences for savory high-prote

161 nce of one or more cofactors, particularly a low-protein diet, thiamine deficiency, alcoholism, and h

162 changes in fat distribution in response to a low-protein diet.

163 day 4 of the high-protein compared with the low-protein diet.

164 ts of soy-protein intake resemble those of a low-protein diet.

165 s the ability of the patient to respond to a low-protein diet.

166 econdary hyperparathyroidism on day 4 of the low-protein diet.

167 rs in the initial IMCD (IMCD1) of rats fed a low-protein diet.

168 ihydroxyvitamin D] in subjects consuming the low-protein diet.

169 the very-low-protein diet compared with the low-protein diet.

170 MA-B (P = 0.004) in participants consuming a low-protein diet.

171 dard diet; a high-carbohydrate, low-fat, and low-protein diet; or a low-carbohydrate, high-fat, and h

172 47, respectively) but not in subjects in the low-protein-diet group (P = 0.384 and 0.078, respectivel

173 reover, there is no evidence that the use of low protein diets (LPD) in the predialysis period result

174 ng most pronounced in female animals fed the low protein diets and the effects of protein reduction b

175 core were significant only in animals on the low protein diets.

176 When low-protein diets are prescribed, patients should be clo

177 Low-protein diets cause a urinary concentrating defect i

178 Canada and snow goose goslings fed low-protein diets had reduced growth rates of the tarsus

179 searched for studies examining the effect of low-protein diets in humans with chronic renal disease.

180 muscle wasting, which may be exacerbated by low-protein diets prescribed to delay disease progressio

181 In rats with renal disease, low-protein diets slow the decline in renal function, hi

182 goose goslings were unable to survive on the low-protein diets, and those fed high- or medium-protein

183 Studies have compared high- and low-protein diets, but there are few data on carbohydrat

184 n Association for the Study of Diabetes, and low-protein diets.

185 s by the gut compared with animals receiving low-protein diets.

186 construed as an argument against the use of low-protein diets.

187 due to maternal malnutrition via high-fat or low-protein diets.

188 ructural size to captive-reared goslings fed low-protein diets.

189 Very low protein-DNA ratio was required if incubations were c

190 At a low-protein dose and over a similar range of plasma CEA,

191 Our analysis revealed a very low protein evolution rate that is at least as slow as i

192 to be fed an MFGM-supplemented, low-energy, low-protein experimental formula (EF) or a standard form

193 od consistently shows increased pressures in low protein exposed rodent offspring compared to control

194 As adults, the low-protein-exposed sheep had reduced glomerular number

195 HR for negative, 1.57; comparison of high v low protein expression HR, P = .049).

196 on of BCL2 transcripts commensurate with the low protein expression level.

197 M motif confer peroxisomal targeting even at low protein expression levels.

198 s that is capable of detecting both high and low protein expression levels.

199 Moreover, we found low protein expression of E. coli LdcC in the feces of s

200 tumors, and colorectal cancer patients with low protein expression of SIRT1 have a poor prognosis.

201 Low protein expression of the antioxidant PRDX2 gene was

202 significant protein misfolding, resulting in low protein expression, cellular mislocalization, and re

203 Low protein expression, protein mislocalization, and red

204 a, and -125b expression was found altered in low protein fed mice.

205 in the apical membrane of initial IMCD from low-protein fed or hypercalcemic rats; (2) active urea r

206 Although low protein feeding increases the contribution of entera

207 We hypothesized that low protein feeding would lower the contribution of amin

208 suggests that degraded habitats with mostly low-protein forage may be able to support Canada gosling

209 et al. concluded that the use of a modified low protein formula (1.7 g protein/100 kcal) is safe.

210 For this reason, using a low-protein formula with an amino acid composition modif

211 Exposure to low-protein grand-maternal diet leads to decreased ovari

212 ts with smaller increases in FGF21 after the low-protein high-fat diet gained more weight after 6 mon

213 ight change was not independent from that of low protein in a multivariate model.

214 stinal calcium absorption explains, in part, low-protein-induced secondary hyperparathyroidism.

215 Nevertheless, feeding a "very-low" protein infant formula may cause limited protein sy

216 valuated the impact of habituation to either low protein intake (LOW PRO) or high protein intake (HIG

217 to derive a similar benefit from a maternal low protein intake as did GDM-exposed offspring.Overall,

218 the long-term developmental consequences of low protein intake in free-living populations remains li

219 In maintenance hemodialysis (MHD) patients, low protein intake is associated with protein-energy was

220 Low protein intake may have additional protective effect

221 with moderate to severe renal insufficiency, low protein intake may slow renal function decline.

222 It remains to be shown whether a relatively low protein intake would cause overeating or would be th

223 dation was substantially suppressed during a low protein intake.

224 ies examining 1) the effects of "high versus low" protein intake or 2) dietary protein's synergistic

225 Abdominal fat was highest with low protein intakes (<16% of energy), and midthigh fat w

226 ariable regression analysis assessed whether low protein intakes and the MST score were predictive of

227 Low protein intakes are unlikely to affect milk volume b

228 te the progression of renal disease and that low protein intakes have beneficial effects.

229 lta cells was unphosphorylated and exhibited low protein kinase activity.

230 t is unable to bind heme exhibits a constant low protein level and an enhanced protein degradation ra

231 be markedly decreased, suggesting that this low protein level produced the observed regulatory effec

232 the disulfide bond linkage patterns, at very low protein levels (<0.5 nmol), in two cysteine-rich pol

233 s might be expected, all the meals contained low protein levels (0.67-3.15 g/100 g) with the highest

234 strocytes and C6 cells: astrocytes expressed low protein levels of Hspa5 compared to C6 cells but acc

235 Low protein levels of RGS2 are associated with various p

236 expression in melanocytes is inhibitory with low protein levels present in surviving cells, suggestin

237 observed Bicoid binding despite vanishingly low protein levels.

238 owever, neuronal SNAREs do promote fusion at low protein/lipid ratios when triggered by higher concen

239 We hypothesized that long-term low protein, low calorie intake and endurance exercise a

240 BMI was lower in the low-protein, low-calorie diet (21.3 +/- 3.1) and runner

241 x hormone-binding globulin was higher in the low-protein, low-calorie diet and runner groups than in

242 ed adiposity, and long-term consumption of a low-protein, low-calorie diet are associated with low pl

243 21 sedentary subjects, who had been eating a low-protein, low-calorie diet for 4.4 +/- 2.8 y (x +/- S

244 I to IGF binding protein 3 were lower in the low-protein, low-calorie diet group (139 +/- 37 ng/mL an

245 l C. pneumoniae challenge, C57BL/6 mice on a low-protein/low-antioxidant diet, but not C57BL/6 mice o

246 ing treatments (n = 8/group): control (CON), low protein (LP) and LP supplemented with BCAA (LP + BCA

247 A low protein (LP) diet improves metabolic health in both

248 and Fgf21-KO mice were placed on control and low protein (LP) diets to assess changes in energy expen

249 al lysine use by the PDV was not affected by low protein (LP) feeding (HP, 213 micromol/kg per h; LP,

250 d either a control (C, 18% casein n = 22) or low protein (LP, 9% casein n = 14) diet.

251 Young progenies in a rat model of maternal low-protein (LP) diet are normoglycemic despite collapse

252 haracterizing progeny of pregnant dams fed a low-protein (LP) diet.

253 was increased 10-fold in mice and rats fed a low-protein (LP) diet.

254 Both maternal malnutrition [notably a low-protein (LP) diet] and stress/glucocorticoid exposur

255 otein-energy malnutrition induced in mice by low-protein (LP) feeding has a detrimental impact on CD8

256 study, we demonstrated that splenocytes from low-protein (LP) guinea pigs vaccinated 6 weeks previous

257 Here we use our maternal low-protein (LP) rat model to determine the effect of ea

258 Conversely, low protein males were relatively hypertensive at 8 week

259 he highest cholesterol-to-protein ratio have low protein mass.

260 re the concentration of SCN(-) is relatively low, proteins may be the principal initial targets of HO

261 us uptake was greatly diminished in maternal low protein (MLP) livers, accounting for a major fractio

262 a modified amino acid profile and a modified low-protein (mLP) content in healthy term-born infants.

263 that is challenged by the tight stacking and low protein mobility in grana.

264 We used an established maternal low-protein model where animals are born small but under

265 The change in EE after a low-protein overfeeding diet is a predictor of weight ch

266 ure (EE) and influences weight change during low-protein overfeeding in rodent models.

267 Low-protein overfeeding may be an important tool to iden

268 The average weight gain during 6 wk of low-protein overfeeding was 3.8 kg (6.1%, min: +2.5%, ma

269 EE during fasting, a smaller EE response to low-protein overfeeding, and a larger response to high-c

270 Under conditions of low protein oxidation (zero to three oxygen atoms added

271 new signal that manifests in late flowering, low protein oxidation during light stress, and enhanced

272 e shown preference and higher performance on low protein (p), high carbohydrate (c) diets as juvenile

273 restriction during lactation (the postnatal low-protein [PLP] group).

274 n micrographs showed crystallized lactose in low protein powders at high water activities.

275 , the rate of water diffusion was higher for low protein powders but high protein powders absorbed hi

276 sociated with diminished mRNA expression and low protein production.

277 Selecting soybean lines with low protein, protein plus oil, calcium, manganese, and b

278 code single-gene phenotypes and tend to have low protein-protein interaction complexity and, as such,

279 sects encounter challenging diets containing low protein quantities, recalcitrant carbohydrate source

280 Furthermore, isolated low Protein S may be causally associated with hepatic ar

281 highest degree of resistance to mAbs showed low protein stability and high local dynamic motions.

282 hr-31 is a key determinant of the relatively low protein stability, thereby promoting apoLp-III to in

283 A low protein state also increased preferences for savory

284 areas (orbitofrontal cortex, striatum) in a low-protein state than in a high-protein state.

285 objective was to investigate the effect of a low protein status compared with a high protein status o

286 arm muscle area indicate muscle wasting and low protein stores.

287 I-BAR domain-driven membrane remodeling at a low protein surface concentration with near-atomistic de

288 mbranes and vesicles, we demonstrate that at low protein surface densities, binding of N-BAR domain p

289 Cells with low glucose uptake capacity and low protein synthesis rates were less ligand-sensitive,

290 , a subpopulation of cells emerges with very low protein synthetic activity.

291 ased bulk diffusion coefficients compared to low protein systems.

292 ed by active niche signaling integration and low protein translation capacity.

293 reversibility of the inhibition and the very low protein turnover rate observed for the enzyme are pa

294 High total fruit and low-protein vegetable intakes were associated with a low

295 Feeding pigs with very-low protein (VLP) diets while supplemented with limiting

296 r adequate protein (AP; 18% protein) or very low protein (VLP; 2% protein) in an established murine m

297 ng either adequate protein (AP; 18%) or very low protein (VLP; 2%) in a mouse model.

298 f diabetes may benefit more from consuming a low-protein weight-loss diet in improving insulin resist

299 e a particular codon usage associated with a low protein yield; AU-rich and GC-rich transcripts tend

300 However, the low protein yields associated with these small samples p