ライフサイエンスコーパス: lumbar spinal cord

1 PTP expression levels in the embryonic chick lumbar spinal cord.

2 hypothalamus project to motor columns in the lumbar spinal cord.

3 locomotor leg movements resides in the upper lumbar spinal cord.

4 d the release of inhibitory molecules in the lumbar spinal cord.

5 ha and -beta mRNA on the injured side of the lumbar spinal cord.

6 structures in the septum, hypothalamus, and lumbar spinal cord.

7 1beta, CCR2, and TLR4 mRNA expression in the lumbar spinal cord.

8 ent the degeneration of motor neurons in the lumbar spinal cord.

9 cle leads to gene transfer in motoneurons of lumbar spinal cord.

10 to suppress FOS-immunoreactivity (FOS-IR) in lumbar spinal cord.

11 together with Fos protein expression in the lumbar spinal cord.

12 heat-evoked fos-like immunoreactivity in the lumbar spinal cord.

13 horn neurones in laminae II-VI of the lower lumbar spinal cord.

14 r autonomic nuclei of the thoracic and upper lumbar spinal cord.

15 neurons that project axons from the brain to lumbar spinal cord.

16 asymmetry in gene expression patterns in the lumbar spinal cord.

17 ersity of excitatory synapses throughout the lumbar spinal cord.

18 functional features and organization of the lumbar spinal cord.

19 at project axons from the mouse brain to the lumbar spinal cord.

20 d Renshaw cell-motoneuron pairs in the mouse lumbar spinal cord.

21 ically connected to the motor neurons in the lumbar spinal cord.

22 ells of origin of the two projections in the lumbar spinal cord.

23 f KCC2 and NKCC1 toward normal levels in the lumbar spinal cord.

24 of motor neurons in the ventral horn of the lumbar spinal cord.

25 systems entirely contained within the local lumbar spinal cord.

26 ence in the density of DA innervation in the lumbar spinal cord.

27 serves a sexually dimorphic function in the lumbar spinal cord.

28 beled motoneurons in the ventral horn of the lumbar spinal cord.

29 on neurons in the rat lumbar DRG and in the lumbar spinal cord.

30 t produce NK1R or MOR internalization in the lumbar spinal cord.

31 atin, captopril and phosphoramidon) onto the lumbar spinal cord.

32 gulation of neuronal/astrocytic GluR1 in the lumbar spinal cord.

33 g IL-1beta, TNF-alpha, CCL2, and TLR4 in the lumbar spinal cord.

34 rocytes and motoneurons (MNs) from the chick lumbar spinal cord.

35 fluorescein dextran amine was applied to the lumbar spinal cord.

36 bnormal isoform of the prion protein, in the lumbar spinal cord.

37 mmunoreactivity as well as their mRNA in the lumbar spinal cord.

38 rathecal catheter with the tip placed in the lumbar spinal cord.

39 r the potential of prion interference in the lumbar spinal cord.

40 on in the abundance of HY TME PrP(Sc) in the lumbar spinal cord.

41 eptor function and subunit expression in the lumbar spinal cord.

42 ical analyses were performed in cervical and lumbar spinal cords.

43 -disulfide isomerase (PDI) family members in lumbar spinal cords.

44 hyperalgesia and Fos protein staining in the lumbar spinal cord 1, 7, 14 and 28 days after unilateral

45 epidural electrical stimulation (EES) of the lumbar spinal cord(1-3) applied during neurorehabilitati

46 ificantly increased microvascular density in lumbar spinal cord, (6) IgG microvascular leakage, (7) r

47 g directly in 12 sporadic ALS and 10 control lumbar spinal cords acquired by a rapid autopsy system t

48 and chemokine-related genes increased in the lumbar spinal cord after RSD, there was no accumulation

49 F-alpha below the level of the lesion in the lumbar spinal cord after T13 lateral hemisection that co

50 was detected at 3 weeks postinfection in the lumbar spinal cord and ascended to the brain at a rate o

51 mRNAs and proteins for NT-3 and TrkC in the lumbar spinal cord and associated soleus muscle followin

52 The lumbar spinal cord and brainstem were evaluated for immu

53 en examined in the L4-5 dorsal root ganglia, lumbar spinal cord and gracile nucleus at 2, 6 and 14 we

54 c changes in motor neuron cell bodies in the lumbar spinal cord and in motor neuron axons in ventral

55 investigate the response of microglia in the lumbar spinal cord and in the brainstem to a tonic noxio

56 blots and immunohistochemistry, ipsilateral lumbar spinal cord and L5 and L6 DRG were analyzed for t

57 pro-inflammatory cytokines/chemokines in the lumbar spinal cord and plasma and decreased mast cell de

58 rived neurotrophic factor (BDNF) in both the lumbar spinal cord and soleus muscle.

59 rmalities included vacuoles initially in the lumbar spinal cord and subsequently in more cervical are

60 ern of their primary axon in the cervical or lumbar spinal cord and supraspinal collateral terminal f

61 corticospinal tracts from the medulla to the lumbar spinal cord and the sensory tracts from the lumba

62 We examined gene expression in the lumbar spinal cord and the specific response of motoneur

63 Lumbar spinal cords and LA muscles from gonadally intact

64 arasagittal and transverse slices of the rat lumbar spinal cord, and examine how these inputs differe

65 Levels of TNFalpha in the thoraco-lumbar spinal cord are also increased at day 8 post-liga

66 ant increase in motor neuron survival in the lumbar spinal cord as well as a significant decrease in

67 (AAV) throughout the cervical, thoracic and lumbar spinal cord, as well as brain motor centers.

68 ion of Inflammatory cytokine IL-1beta in the lumbar spinal cord, as well as its role in chronic pain.

69 is model, UPR activation was detected in the lumbar spinal cord at 6 months then declined at 12 month

70 oduces (a) a decrease in mu receptors in the lumbar spinal cord; (b) a decrease in the affinity of li

71 At the same time, in vitro isolated lumbar spinal cords became hyperreflexive and displayed

72 the levels of both neurotransmitters in the lumbar spinal cord beyond normal.

73 ability to TNF was increased not only in the lumbar spinal cord but also in brain and distal spinal c

74 Inosine did not affect CST sprouting in the lumbar spinal cord but did restore levels of the growth-

75 hroughout the gray matter in control and ALS lumbar spinal cord, but was significantly and selectivel

76 ssociated with enhanced reinnervation of the lumbar spinal cord by 5-HT axons.

77 30-40% more motoneurons in the brachial and lumbar spinal cord by the end of the normal period of ce

78 that epidural electrical stimulation of the lumbar spinal cord can reproduce the natural activation

79 (i.e., periaqueductal gray and subarachnoid lumbar spinal cord) can reduce pain sensitivity of rats

80 In embryonic lumbar spinal cord, cell-cell coupling is widespread in

81 uencing to profile how each cell type in the lumbar spinal cord changes after a thoracic injury in mi

82 ce results in DA concentrations in the adult lumbar spinal cord comparable to those of males.

83 g GABA, and reducing glutamate levels in the lumbar spinal cord, consistent with a spinal site of act

84 a population of spinothalamic neurons in the lumbar spinal cord containing several neuropeptides incl

85 Regions of the thoraco-lumbar spinal cord containing sympathetic preganglionic

86 f lumbar-projecting A(11) DA neurons and the lumbar spinal cord DA concentrations, organized by the p

87 mals without manifestation of disease had no lumbar spinal cord demyelination.

88 f the features of excitatory synapses in the lumbar spinal cord, detailing synaptic diversity that is

89 early genes have been shown to occur in the lumbar spinal cord dorsal horn after peripheral inflamma

90 ary tract (NTS), and caudal thoracic/rostral lumbar spinal cord dorsal horn.

91 ns of spinocerebellar neurons in the thoraco-lumbar spinal cord: dorsal spinocerebellar tract neurons

92 phosphatase, were severely diminished in the lumbar spinal cord, DRG, and hindlimb skin.

93 nd p75, appeared qualitatively normal in the lumbar spinal cord, DRG, and hindlimb skin.

94 tion and impulse conduction in the Lewis rat lumbar spinal cord during the clinical course of acute E

95 In rodent lumbar spinal cord, extensive gap junctional coupling am

96 Moreover, in caudal lumbar spinal cord extracts from a set of paraplegic rab

97 HY TME spread from the sciatic nerve to the lumbar spinal cord followed by transsynaptic spread and

98 we found no obvious staining differences in lumbar spinal cord following the chronic constriction in

99 ffects of estrogen on gene expression in the lumbar spinal cord, following sciatic nerve crush injury

100 eparate extraction of cervical, thoracic and lumbar spinal cord for immunochemical assay.

101 (heart rate and mean arterial pressure), and lumbar spinal cord Fos expression in control rats and in

102 Neural circuitry in the lumbar spinal cord governs two principal features of loc

103 hen administered intrathecally (i.t.) to the lumbar spinal cord, GSK189254 produced robust effects in

104 Epidural stimulation (ES) of the lumbar spinal cord has demonstrated significant improvem

105 cells in the superficial dorsal horn of the lumbar spinal cord have silent synapses: they do not res

106 e denervated gray matter of the cervical and lumbar spinal cord; however, EPO treatment further signi

107 or neuron density in the ventral horn of the lumbar spinal cord in G93A mice.

108 We examined whether the lumbar spinal cord in postnatal day 5 neonatal spinally

109 al analysis of cell extracts from the caudal lumbar spinal cord indicated that there was increased pr

110 f SB 203580 blocked the increased GFAP-IR in lumbar spinal cord induced by pSNL.

111 In lumbar spinal cord, inflammatory signaling is reduced in

112 h chronic incomplete cervical, thoracic, and lumbar spinal cord injury were randomly assigned to 10 s

113 o the same populations of neurons within the lumbar spinal cord, interference between HY TME and DY T

114 ective antagonist) in the dorsal quadrant of lumbar spinal cord ipsilateral to nerve injury.

115 ed that, in rats, release of oxytocin in the lumbar spinal cord is not limited to conventional synaps

116 the brain and brainstem that project to the lumbar spinal cord, leading to paralysis.

117 s direct manipulations of the neurons in the lumbar spinal cord led to muscle spasms without meaningf

118 bers and initially entered the simian CNS at lumbar spinal cord levels.

119 ly invasive, intrathecal delivery of NPCs at lumbar spinal cord (lumbar puncture) represents an impor

120 ALS lumbar spinal cord lysates similarly show increased cyto

121 s and recordings of motor output, in the rat lumbar spinal cord maintained in vitro, to demonstrate t

122 Treatment with CLC increased the number of lumbar spinal cord motoneurons that survived the cell de

123 There was no significant loss of lumbar spinal cord motor neurons in the MOG peptide-EAE

124 pinal IGF-1 expression and partial rescue of lumbar spinal cord motor neurons, as well as sex-specifi

125 These results suggest that lumbar spinal cord neurons are sensitized during the dev

126 GDNF were transplanted unilaterally into the lumbar spinal cord of 18 ALS participants in a phase 1/2

127 (NR1) subunit was selectively deleted in the lumbar spinal cord of adult mice by the localized inject

128 s and retrodorsolateral nucleus of the lower lumbar spinal cord of adult rats.

129 significant elevation of C(16:0)-Cer in the lumbar spinal cord of EAE mice.

130 f pain-associated reactive astrocytes in the lumbar spinal cord of HIV-1 gp120 transgenic mice using

131 lved a reduction in neuronal activity in the lumbar spinal cord of humans during walking.

132 id; DOPAC) of A11 DA neurons innervating the lumbar spinal cord of male and female C57/BL6 mice, and

133 tau, MAP2, synaptophysin and drebrin in the lumbar spinal cord of non-diabetic and streptozotocin-di

134 ha and monocyte chemoattractant protein 1 in lumbar spinal cord of paclitaxel-treated WT mice.

135 The lumbar spinal cord of rats contains the sexually dimorph

136 of Fos protein-like immunoreactivity in the lumbar spinal cord of rats with complete spinal transect

137 s injected into the intrathecal space of the lumbar spinal cord of rats.

138 d white matter of the medulla, cervical, and lumbar spinal cord of SALS patients are novel findings.

139 al spinal neural stem cells (hNSCs) into the lumbar spinal cord of SOD1(G93A) rats leads to a moderat

140 Grafting of hNSCs into the lumbar spinal cord of SOD1(G93A) rats protected alpha-mo

141 ease in microgliosis and astrogliosis in the lumbar spinal cord of SOD1(G93A) transgenic mice before

142 d the levels of glutamate and glycine in the lumbar spinal cord of spinally transected rats.

143 oduct of membrane lipid peroxidation, in the lumbar spinal cord of sporadic amyotrophic lateral scler

144 sed TNF-alpha and FasL immunostaining in the lumbar spinal cord of the G93A SOD1 transgenic mice occu

145 ized sexually dimorphic motor nucleus in the lumbar spinal cord of the male rat.

146 n-dependent population of motoneurons in the lumbar spinal cord of the rat, to partial motoneuron dep

147 both sexually dimorphic motor nuclei in the lumbar spinal cord of the rat.

148 rough a density cushion were inoculated into lumbar spinal cords of 100-day-old mice carrying a human

149 n motor neuron counts or glial activation in lumbar spinal cords of liraglutide treated mice compared

150 Tissue concentrations of hIGF-1 in lumbar spinal cords of mice infused with IGF-1:TTC were

151 l hyperalgesia and Fos expression within the lumbar spinal cord on days 14, 35 and 55 after either CC

152 , chosen to include (hindbrain, cervical and lumbar spinal cord), or exclude (dorsal telencephalon) p

153 vector encoding human IGF-1 (CERE-130) into lumbar spinal cord parenchyma of SOD1(G93A) mice.

154 disruption of the BBB by compression of the lumbar spinal cord, permeability to TNF was increased no

155 Lumbar spinal cord PET signal was significantly higher i

156 ect to extrahypothalamic brain areas and the lumbar spinal cord play an important role in the control

157 n, paw skin, lumbar dorsal root ganglia, and lumbar spinal cord, postinfection (p.i.).

158 hat neurons in different segments of the rat lumbar spinal cord process information from group II aff

159 ficantly with small fibre axonal loss in the lumbar spinal cord (r = -0.832, P = 0.003) only in HLA-D

160 conjugated to saporin to demyelinate the rat lumbar spinal cord, remove macroglia, and produce parapl

161 haw cells and their dendrites in cat and rat lumbar spinal cord, respectively.

162 Immunohistochemistry of lumbar spinal cord revealed aberrant expression level an

163 However, examination of the lumbar spinal cord revealed the following changes.

164 amyotrophic lateral sclerosis (ALS) than in lumbar spinal cord samples from neurologically normal pa

165 Here, we report higher Par-4 levels in lumbar spinal cord samples from patients with amyotrophi

166 We also compared the levels of Par-4 in lumbar spinal cord samples from wild-type and transgenic

167 amples, higher Par-4 levels were observed in lumbar spinal cord samples prepared from the transgenic

168 xpression arrays were used to compare murine lumbar spinal cord (SC) and dorsal root ganglion (DRG) g

169 scular Blockade (NMB) and another undergoing lumbar spinal cord (SC) transection, both serving as con

170 Silver impregnation of lumbar spinal cord sections and descending motor axon co

171 eased TNF-alpha and FasL immunoreactivity in lumbar spinal cord sections of ALS patients and G93A tra

172 Further analyses of adjacent lumbar spinal cord sections revealed that many, although

173 unohistochemical analyses of human and mouse lumbar spinal cord sections revealed that Par-4 is local

174 Lumbar spinal cord sections showed gamma2 immunostaining

175 ath genes, bcl-2 and bax, in control and ALS lumbar spinal cord sections.

176 rode was placed on the left dorsal column at lumbar spinal cord segments 2-3 in sodium pentobarbital

177 stmortem samples from cervical, thoracic and lumbar spinal cord segments from 154 individuals with AL

178 dorsal horn of the caudal thoracic and upper lumbar spinal cord segments.

179 d inflammation within the dorsal horn of the lumbar spinal cord.SIGNIFICANCE STATEMENT Mounting evide

180 In rat lumbar spinal cord slices, we now demonstrate that condi

181 ade with biocytin-filled electrodes from rat lumbar spinal cord slices.

182 Neurites from rostral (cervical) and caudal (lumbar) spinal cord slices exhibit distinct growth prefe

183 S) functionality during micturition, the mid-lumbar spinal cord (specifically L3) was targeted in the

184 an be activated via lower thoracic and upper lumbar spinal cord stimulation to produce an effective c

185 ignificantly higher DA concentrations in the lumbar spinal cord than either females or males carrying

186 ns, more infectious virus was present in the lumbar spinal cord than in the cervical spinal cord.

187 ), a sexually dimorphic motor nucleus in the lumbar spinal cord that controls penile reflexes involve

188 bitory effects on dorsal horn neurons in the lumbar spinal cord that receive nociceptive input from c

189 evels after tissue injury, in the normal rat lumbar spinal cord, the majority of neurons and radial g

190 ocated group of somatic motor neurons in the lumbar spinal cord, the retrodorsolateral nucleus, showe

191 descending propriospinal projections to the lumbar spinal cord, therefore, produce inhibitory effect

192 Western blot analyses of lumbar spinal cord tissue from spastic animals showed a

193 Lumbar spinal cord tissues were examined 7 days after th

194 eract with higher centers and the sacral and lumbar spinal cord to coordinate complex voiding behavio

195 ion in parasagittal and transverse slices of lumbar spinal cord to stimulate presynaptic neurons by g

196 unctional connectivity features of the human lumbar spinal cord using resting-state fMRI (rs-fMRI) at

197 brain, and clearance from the brain stem and lumbar spinal cord was delayed, followed by reactivation

198 etic and somatic motor outflows from thoraco-lumbar spinal cord was investigated in a novel arteriall

199 Lumbar spinal cord was removed and immunostained for M4

200 tor-alpha and estrogen receptor-beta mRNA in lumbar spinal cord was shown by traditional RT-PCR.

201 scope examination of brainstem, cervical and lumbar spinal cords was performed in ALS mice at early a

202 DA concentrations in the lumbar spinal cord were higher in males, suggesting a gr

203 inhibition of rat dorsal horn neurons of the lumbar spinal cord were tested.

204 at about 12-13 or 19 weeks of age, and their lumbar spinal cords were processed for histo- and immuno

205 d by real-time PCR, was more abundant in the lumbar spinal cord, while HSV-2 DNA was more abundant in

206 ress increases GABA(B(1a)) expression in the lumbar spinal cord, with no commensurate change in therm

207 ine (by approximately 85% of control) in rat lumbar spinal cord without altering levels of dopamine o