ライフサイエンスコーパス: lung biopsy

1 tal hernia, and subcutaneous emphysema after lung biopsy).

2 are being evaluated to decrease the need for lung biopsy.

3 id, and characteristic histologic changes on lung biopsy.

4 ist are sufficient to obviate the need for a lung biopsy.

5 titial pneumonia (UIP) confirmed by surgical lung biopsy.

6 ovided an overall diagnosis, before surgical lung biopsy.

7 pneumonia had the vaccine strain of VZV in a lung biopsy.

8 atients had idiopathic PAP confirmed by open lung biopsy.

9 high-resolution chest CT (HRCT) or surgical lung biopsy.

10 ls found in bronchoalveolar lavage fluid and lung biopsy.

11 , bronchoalveolar lavage, and transbronchial lung biopsy.

12 agnoses inconsistently confirmed by adequate lung biopsy.

13 ts, often obviating the need to perform open-lung biopsy.

14 eries of patients diagnosed by bronchoscopic lung biopsy.

15 F) diagnosis without the need for a surgical lung biopsy.

16 of pneumothorax after CT-guided percutaneous lung biopsy.

17 transbronchial lung cryobiopsy, and surgical lung biopsy.

18 for the increased risk associated with open lung biopsy.

19 te of pneumothorax at CT-guided percutaneous lung biopsy.

20 he immunohistochemical features on liver and lung biopsy.

21 Of these, 407 underwent lung biopsy.

22 nchoalveolar lavage, genetic testing, and/or lung biopsy.

23 ent a biopsy of each lung, for a total of 20 lung biopsies.

24 mograms, blood chemistries, radiographs, and lung biopsies.

25 t based on the results of the transbronchial lung biopsies.

26 nosis, often obviating the need for surgical lung biopsies.

27 udies failed to find molecular AMR (ABMR) in lung biopsies.

28 less conclusively predict the COPD status of lung biopsies.

29 the most highly upregulated in SSc skin and lung biopsies.

30 cal symptoms and, if available, CT scans and lung biopsies.

31 s for interstitial lung disease and surgical lung biopsies.

32 immunohistochemical staining of IPF surgical lung biopsies.

33 e-related mortality was four-fold higher for lung biopsy (0.0078) compared with BAL (0.0018).

34 However, complications were more common with lung biopsy (0.15 v 0.08; P = .006), and procedure-relat

35 nosis was more common with BAL compared with lung biopsy (0.49 v 0.34; P < .001).

36 d (2), liver biopsy (2), colonic biopsy (1), lung biopsy (1), and stool (1).

37 tients were diagnosed to have amyloidosis by lung biopsy (15 surgical, 2 transthoracic needle, and 1

38 All cases underwent lung biopsies: 58 were BLC, and 59 were surgical lung bi

39 Conclusion During CT-guided percutaneous lung biopsy, a protocol of positioning biopsy-side down,

40 s and are well equipped to perform CT-guided lung biopsies, adhering closely to the principles outlin

41 total of 49 soldiers underwent thoracoscopic lung biopsy after noninvasive evaluation did not provide

42 Of the 49 soldiers who underwent lung biopsy, all biopsy samples were abnormal, with 38 s

43 T and CXCR3 expression in human IPF surgical lung biopsies and assessed whether CXCR3 and its ligand

44 Messenger RNA in transbronchial lung biopsies and bronchoalveolar lavage cell pellet and

45 samples, miR-17~92 expression was reduced in lung biopsies and lung fibroblasts from patients with IP

46 SHH) pathway members in normal and IPF human lung biopsies and primary fibroblasts.

47 ife-threatening complication of percutaneous lung biopsy and ablation.

48 Thoracoscopic lung biopsy and bronchoalveolar lavage were not conducte

49 disease (ILD) patients undergoing diagnostic lung biopsy and conducted single-cell RNA-Seq on spare t

50 y discussions, guiding the need for surgical lung biopsy and determining available pharmacologic ther

51 The mean cost per patient for lung biopsy and pneumothorax management was as follows:

52 analysis, and suggestions for transbronchial lung biopsy and surgical lung biopsy were also made.

53 The pathology of transbronchial lung biopsy and the findings of bronchoalveolar lavage f

54 pathologic evidence of fibrosis at surgical lung biopsy and to compare a usual interstitial pneumoni

55 obtained from two patients 1 to 2 days after lung biopsy and which were sterile by culture were posit

56 and bilateral pneumothorax after unilateral lung biopsy), and thoracic wall (infections, transdiaphr

57 cells in vitro, colocalizes to mast cells in lung biopsies, and is elevated in asthmatic airways.

58 minantly solid pattern of LAM lesions in the lung biopsy, and greater rate of decline in expiratory f

59 ng studies, bronchoalveolar lavage, surgical lung biopsy, and histopathologic assessment, improved ou

60 on complications after transthoracic needle lung biopsy are limited to case series from selected ins

61 ngs alone and for considering transbronchial lung biopsy as a diagnostic tool.

62 olution CT as part of screening and surgical lung biopsy as part of standard clinical care.

63 iNOS was measured in central and peripheral lung biopsies, as well as BAL cells.

64 try, blood analyses, chest radiographs, open lung biopsies, as well as tissue drug concentrations and

65 cant reduction (P < .016) in intraprocedural lung biopsy-associated pneumothorax was found when the e

66 A surgical lung biopsy at the time of grafting revealed characteris

67 We examined RGS4 expression in human lung biopsies by immunohistochemistry.

68 Transbronchial lung biopsy can be performed with an acceptable risk and

69 ressed at significantly higher levels in UIP lung biopsies compared with biopsies from patients with

70 nts (22%) in the bellows group who underwent lung biopsy compared with 16 of 50 (32%) patients in the

71 In CT-guided lung biopsies, complication risk can be reduced by optim

72 number of cores was a predictive factor for lung biopsy complications.

73 ybridization (FISH) studies performed on the lung biopsy confirmed a normal XY genotype.

74 patients served as a control group.Methods: Lung biopsy cores from decedents underwent viral culture

75 with the same species or 1 bronchoscopic or lung biopsy culture).

76 Histologic analysis of transbronchial lung biopsies demonstrated a few eosinophils within the

77 e, bronchoalveolar lavage lymphocytosis, and lung biopsy demonstrating granulomas, inflammation, and

78 everity of fibrosis and cellularity found on lung biopsy determine the prognosis and response to ther

79 s well as new insights into the role of open lung biopsy, diaphragmatic dysfunction, and a potential

80 Surgical lung biopsies disclosed nonspecific interstitial pneumon

81 In suspected cases, surgical lung biopsy early in the clinical course could be consid

82 To test this hypothesis, we obtained open lung biopsies either from normal patients undergoing tho

83 mplication rate after percutaneous CT-guided lung biopsy, especially chest tube insertion.

84 s, detecting chest wall invasion by tumours, lung biopsy, estimating pleural effusion volume, and pre

85 ematologic malignancy, who underwent 67 open lung biopsies for diagnosis of an unknown pulmonary proc

86 We recruited 18 patients with fILD awaiting lung biopsy for [(18)F]FDG PET/CT.

87 F diagnosis conditionally recommend surgical lung biopsy for histopathology diagnosis of UIP when rad

88 n-hospital mortality after elective surgical lung biopsy for interstitial lung disease is just under

89 c lung pathology as well as a transbronchial lung biopsy for molecular testing with Envisia Genomic C

90 pients of HSCT, and if they underwent BAL or lung biopsy for the evaluation of pulmonary lesions.

91 Pathologists reviewed surgical lung biopsies from 108 patients with usual interstitial

92 Lung biopsies from 11 patients with pulmonary eosinophil

93 We profiled lung biopsies from 15 patients with IPF, 12 with HP, and

94 Mitochondria were analysed in lung biopsies from 30 patients with idiopathic or connec

95 , histologic diagnoses of ALI and OP in 4786 lung biopsies from 803 adult lung recipients.

96 We took 125 surgical lung biopsies from 86 patients.

97 itro repeated incubation with IL-13, and (3) lung biopsies from COPD and healthy patients.

98 Open lung biopsies from eight patients with CFA, nine patient

99 Lung biopsies from patients infected with H1N1 revealed

100 We obtained open lung biopsies from patients undergoing thoracic surgery

101 Selective spatial transcriptomic analysis of lung biopsies from patients with COVID-19 shows the pres

102 Phosphorylated STAT-3 was elevated in lung biopsies from patients with idiopathic pulmonary fi

103 We used tissue sections of surgical lung biopsies from patients with IPF to localize express

104 Here, we report that RNA sequencing of lung biopsies from patients with RA-ILD and IPF revealed

105 elta2 T-cell infiltration were observed in a lung biopsy from a fatal SARS-CoV-2 infection.

106 tasis on HRCT and had not undergone surgical lung biopsy had disease that progressed in a similar way

107 problems such as empyema, pneumothorax, and lung biopsy has significantly altered our treatment algo

108 Single-cell RNA sequencing from human lung biopsies identified macrophages as a source of OSM.

109 ctive diagnoses of AR and LB from over 2,000 lung biopsies in 400 newly transplanted adult lung recip

110 a 2.9-fold increased MSK1 mRNA expression in lung biopsies in patients at 6 months before CLAD diagno

111 The yield and impact of open lung biopsies in patients with hematologic malignancies

112 ia in bronchoalveolar lavage fluid (BALF) or lung biopsies in the absence of infection, atopy, or ast

113 issue available for histopathology (surgical lung biopsy in 28 patients and explanted lung in two pat

114 cases (61.8%); clinical history and surgical lung biopsy in 56 cases (18.1%); and clinical history an

115 psy as an acceptable alternative to surgical lung biopsy in centers with appropriate expertise.

116 puted tomography, thus avoiding the need for lung biopsy in most patients.

117 We conclude that open lung biopsy in patients with hematologic malignancy has

118 to permit diagnosis of IPF without surgical lung biopsy in select cases when CT shows a probable UIP

119 Bronchoalveolar fluid analysis and lung biopsy in selected case reports revealed several di

120 rated in the COLDICE (Cryobiopsy versus Open Lung Biopsy in the Diagnosis of Interstitial Lung Diseas

121 st computed tomography, genetic testing, and lung biopsy in the diagnostic evaluation of children wit

122 ion rate of bronchoalveolar lavage (BAL) and lung biopsy in the evaluation of pulmonary lesions in pa

123 ywords: Biopsy/Needle Aspiration, CT, Lungs, Lung Biopsy, Interventional Bronchoscopy(C) RSNA, 2023.

124 samples obtained with percutaneous CT-guided lung biopsy is associated with postprocedural complicati

125 Lung biopsy is most helpful when clinical and radiologic

126 It is not known if a surgical lung biopsy is necessary in all patients for the diagnos

127 Surgical lung biopsy is often required for a confident multidisci

128 Lung biopsy light microscopy demonstrated a marked reduc

129 tissue samples from all the cases for which lung biopsy material was available (15 of 20 cases known

130 Further diagnostic measures, including lung biopsies, may be limited to rare, complicated cases

131 Lung biopsy more commonly led to a noninfectious diagnos

132 al study participants referred for CT-guided lung biopsy (n = 2052) were assessed for enrollment.

133 In patients undergoing surgical lung biopsy (n = 86), after adjusting for guideline-base

134 7.3%) by bronchoalveolar lavage (n=68), open lung biopsy (n=3), or autopsy (n=14).

135 s: previous chest operations other than open lung biopsy (n=6 patients having 1-4 previous operations

136 nd their corresponding receptors in surgical lung biopsies obtained at the time of disease diagnosis

137 An open-lung biopsy obtained from the second patient allowed a q

138 Lung function of 143 patients and lung biopsies of 74 of these patients were reviewed for

139 mechanistic action of EGCG by investigating lung biopsies of patients with mild interstitial lung di

140 [(18)F]FDG uptake with histologic markers on lung biopsy of patients with fibrotic interstitial lung

141 alysis of 104 patients with IPF who had open lung biopsy (OLB) at Mayo Medical Center from 1976 to 19

142 done in 94.7% of patients and surgical open lung biopsy (OLB) in 20.3%.

143 n computed tomography (HRCT, n = 25) or open-lung biopsy (OLB, n = 1) patterns typical for idiopathic

144 g patients biopsy side down during CT-guided lung biopsy on the incidence of pneumothorax, chest drai

145 oscopy with transbronchial and endobronchial lung biopsies or endosonography (esophageal or endobronc

146 histopathologic presence of the organism at lung biopsy or (b) a positive culture of a respiratory s

147 e such patients who had undergone diagnostic lung biopsy or autopsy were examined.

148 the basis of histopathological appearance at lung biopsy or autopsy, they have been termed: alveolar

149 y specimens and lung tissue obtained by open-lung biopsy or post mortem examination occurred in 11 (8

150 ties in a subset of patients undergoing open lung biopsy or transplantation or whose lung tissue was

151 ormalities underwent bronchoalveolar lavage, lung biopsy, or both.

152 RATIONALE: In the absence of a surgical lung biopsy, patients diagnosed with idiopathic pulmonar

153 estimated there to be around 12,000 surgical lung biopsies performed annually for interstitial lung d

154 requent complication of transthoracic needle lung biopsy, pneumothorax is common and often necessitat

155 s the current standard of care for CT-guided lung biopsy; positioning biopsy side down was hypothesiz

156 The extent of fibroblastic foci present on lung biopsy predicts survival in IPF.

157 The use of specimens acquired from lung biopsy procedures to identify biomarkers of clinica

158 Eighty-three transbronchial lung biopsy procedures were performed in this patient co

159 is could be attributed to the transbronchial lung biopsy procedures.

160 al aspiration, or percutaneous transthoracic lung biopsy (PTLB).

161 biopsy side down for percutaneous CT-guided lung biopsy reduced the incidence of pneumothorax compar

162 during percutaneous CT-guided transthoracic lung biopsy reduces the rate of overall pneumothorax and

163 ted tomographic (CT) scans of the chest, and lung biopsy reports were submitted by referring centers

164 76 years) with chronic HP had their surgical lung biopsy results reviewed by two pathologists for the

165 In situ hybridization of IPF lung biopsies revealed that miR-144-3p is expressed in f

166 hoalveolar lavage were unrevealing, and open lung biopsy revealed active small vessel vasculitis.

167 Open lung biopsy revealed extrinsic allergic alveolitis (hype

168 Trans-bronchial lung biopsy revealed intraluminal organization and fibri

169 Lung biopsy revealed perivascular and interstitial eosin

170 An open lung biopsy revealed pulmonary capillaritis.

171 Immunostaining studies of the proband's lung biopsy revealed that RAB5B and EE marker EEA1 were

172 An unknown virus was isolated from a lung biopsy sample and multiple other samples from a pat

173 existing and subsequently obtained surgical lung biopsy samples and from lung explants.

174 stomorphometric analysis of small airways in lung biopsy samples collected from 50 soldiers with post

175 ual interstitial pneumonia in transbronchial lung biopsy samples from 49 patients with 88% specificit

176 ere obtained from 49 patients and 55 in vivo lung biopsy samples from computed tomographic [CT]-guide

177 We collected surgical lung biopsy samples from patients with various interstit

178 Three to five transbronchial lung biopsy samples were collected from all patients spe

179 Open lung biopsy samples were scored for cellular infiltratio

180 equire histological confirmation of surgical lung biopsy samples when high-resolution CT images are n

181 ls in bronchoalveolar lavage fluid, blood or lung biopsy samples, and rapid response to corticosteroi

182 ng algorithm in less-invasive transbronchial lung biopsy samples.

183 versus normal areas of lung in IPF surgical lung biopsy samples.

184 other interstitial lung diseases in surgical lung biopsy samples.

185 IPF had both high-resolution CT and surgical lung biopsy samples.

186 lung tissue was obtained from donated normal lungs, biopsy samples of transplanted lungs, and explant

187 onia pattern on high resolution CT, surgical lung biopsy sampling might not be necessary to reach a d

188 he primary outcome was comparison of average lung biopsy scores at 6 months.

189 Consecutive paraffin-embedded lung biopsy sections were immunostained for alveolar and

190 osis was idiopathic pulmonary fibrosis; open lung biopsy shortly before his death confirmed asbestosi

191 ary capillaritis may have negative serology, lung biopsy should be strongly considered in any child w

192 dditional investigations, including surgical lung biopsy, should be considered in patients with eithe

193 Trans-bronchial lung biopsy showed lymphocytic infiltration of the alveo

194 Histopathology from the lung biopsy showed structures consistent with B. dermati

195 over, heparanase content was higher in human lung biopsies showing diffuse alveolar damage than in no

196 and six of these patients also had surgical lung biopsy showing a pattern consistent with chronic hy

197 A video-assisted thoracoscopic lung biopsy shows findings of usual interstitial pneumon

198 Findings of surgical lung biopsy (SLB) are important in categorizing patients

199 chial lung cryobiopsy (TBLC)-versus surgical lung biopsy (SLB) as the current gold standard-in inters

200 ography has limited resolution, and surgical lung biopsy (SLB) carries risks of morbidity and mortali

201 ut prospective studies with matched surgical lung biopsy (SLB) have yielded conflicting results.

202 thologic agreement between TBLC and surgical lung biopsy (SLB) was demonstrated in the COLDICE (Cryob

203 stic accuracy of TBLC compared with surgical lung biopsy (SLB), in the context of increasing use of T

204 biopsies: 58 were BLC, and 59 were surgical lung biopsy (SLB).

205 pulmonary fibroblasts grown out of surgical lung biopsies (SLBs) from IIP patients based on their ex

206 Staining of UIP lung biopsy specimens demonstrated that phosphorylated S

207 Lung biopsy specimens from asthmatic and nonasthmatic pa

208 Staining of lung biopsy specimens from patients with acute lung inju

209 Paraffin-embedded lung biopsy specimens from patients with RA (n = 15) and

210 Lung biopsy specimens from patients with RA-associated i

211 Open-lung biopsy specimens from patients with RA-associated I

212 Recut sections were obtained from lung biopsy specimens from seven male recipients of tran

213 emodeling-associated genes in transbronchial lung biopsy specimens from two cohorts with 18 patients

214 tion were examined in fibroblasts grown from lung biopsy specimens obtained from 16 scleroderma patie

215 T-cell lines derived from lung biopsy specimens of asthmatic patients were charact

216 Gastrointestinal and lung biopsy specimens of subjects with inflammatory dise

217 With open lung biopsy specimens the following assays yielded the i

218 At each time point, lung biopsy specimens were scored for rejection.

219 Bronchoalveolar lavage (BAL) fluid and lung biopsy specimens were stained with hematoxylin and

220 ngulfing degenerating lamellar bodies and/or lung biopsy specimens with alveolar spaces filled with h

221 nd 24 formalin-fixed, paraffin-embedded open lung biopsy specimens.

222 which we showcase for the exemplar of human lung biopsy specimens.

223 eous analysis of the 16 DNA adducts in human lung biopsy specimens.

224 otein receptor type 1A (BMPR1A) and BMPR2 in lung-biopsy specimens from patients with pulmonary hyper

225 Bronchoscopy and transbronchial lung biopsy (TBLB) are the gold standard of diagnosis.

226 th noncaseating necrosis from transbronchial lung biopsy (TBLB) specimen, increasing of lymphocyte an

227 positive plus had histopathology on surgical lung biopsy that was consistent with hypersensitivity pn

228 ge fluid; and three had findings on surgical lung biopsy that were consistent with subacute hypersens

229 s had histopathological features on surgical lung biopsy that were consistent with this diagnosis.

230 Bronchoscopy with transbronchial lung biopsies, the current diagnostic standard, has mode

231 olecular diagnosis of UIP" in transbronchial lung biopsy, the Envisia Genomic Classifier, accurately

232 T characteristics but are unfit for surgical lung biopsy, therefore preventing a confident diagnosis.

233 Immunohistochemistry of lung biopsy tissue in five HIV-negative patients showed

234 In addition, five soldiers received a lung biopsy; tissue results were compared to a previousl

235 In gastrointestinal and lung biopsy tissues of patients with CVID, numerous IFN-

236 robust comparative approach utilizing human lung biopsies to characterize the immunological landscap

237 oalveolar lavage and repeated transbronchial lung biopsies to determine progression to chronic beryll

238 to the contrary, we have found bronchoscopic lung biopsy to be a safe and effective diagnostic techni

239 n immunocompetent patient documented at open lung biopsy to be due to Mycobacterium haemophilum.

240 hout a typical NEHI presentation, and thus a lung biopsy to differentiate the diseases is indicated.

241 dentify patients who should undergo surgical lung biopsy to secure a definitive histological diagnosi

242 with interstitial lung disease referred for lung biopsy underwent sequential TBLC and SLB under one

243 paraffin-embedded lung biopsies with normal lung biopsies, using immunostaining, RNA sequencing, and

244 Cellular infiltration score of the open lung biopsies was higher in responders (7.6+/-0.6) than

245 repeat spoligotyping of 85 paraffin-embedded lung biopsies was used to investigated the occurrence ar

246 duration of symptoms 4.6 yr, and time since lung biopsy was 3.2 yr.

247 clinician, radiologist, and pathologist (if lung biopsy was completed) independently evaluated each

248 Lung biopsy was most important for diagnosis in those pa

249 08 and December 2009, percutaneous CT-guided lung biopsy was performed in 201 patients.

250 In the three patients in whom open lung biopsy was performed, there was bronchiolocentric i

251 Serial lung biopsies were examined by light microscopy and immu

252 Concurrent proximal airway and distal lung biopsies were obtained by bronchoscopy from subject

253 amples from computed tomographic [CT]-guided lung biopsies were obtained from 25 patients) and quanti

254 Before, during, and after CPB, peripheral lung biopsies were performed to determine tissue NO, nit

255 160 coaxial computed tomography (CT)-guided lung biopsies were performed.

256 y (CT) guided and 24 fluoroscopically guided lung biopsies were performed.

257 The lung biopsies were reviewed by a pathology core and 54 o

258 for transbronchial lung biopsy and surgical lung biopsy were also made.

259 Patients undergoing CT-guided lung biopsy were either positioned in (a) the standard p

260 s were screened; 72 studies of BAL and 31 of lung biopsy were included.

261 Other procedures including lung biopsy were performed if clinically indicated.

262 is diagnosed with the use of transbronchial lung biopsies, which are invasive, expensive, and subjec

263 een validated by a preliminary test on human lung biopsy, which has confirmed the ex-vivo CK17 detect

264 examined and compared EGPA paraffin-embedded lung biopsies with normal lung biopsies, using immunosta