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1 ithelial, blood, induced sputum, T cells and lymphoblastoids).
2 atency III proliferating B cells, on various lymphoblastoid and Burkitt lymphoma cell lines, some of
4 ased levels of CSF KYNA (P=0.03) and reduced lymphoblastoid and hippocampal KMO expression (P</=0.05)
5 of which were profiled in both the GM12878 (lymphoblastoid) and K562 (erythroleukemic) human hematop
6 covered that in human cancer cells (myeloma, lymphoblastoid, and breast cancer), when expression of h
7 of transcription start sites (TSSs) in human lymphoblastoid B cell (GM12878) and chronic myelogenous
11 ow that Epstein-Barr virus (EBV) transformed lymphoblastoid B-cell lines (LCLs) not only express DEC-
12 *01:01 and HLA-G*01:01 were transfected into lymphoblastoid C1R cells expressing low endogenous HLA.
19 his study, integrative analyses of published lymphoblastoid cell line (LCL) Hi-C data and our 4C-seq
24 nome RNA-seq analysis between mouse vHpc and lymphoblastoid cell line cultures from control women and
40 C-seq by sequencing the methylome of a human lymphoblastoid cell line to approximately 8.6x high-qual
41 C data of chromosome 5 from GM12878 (a human lymphoblastoid cell line), (ii) 40-kb resolution whole-g
42 from GM06990, a near-normal EBV-transformed lymphoblastoid cell line, and have compared origin distr
43 Applied to high-resolution Hi-C data in a lymphoblastoid cell line, HiC-DC detects significant int
44 for PBL-to-atrium; and from 0.81 to 0.98 for lymphoblastoid cell line-to-PBL based on cross-validatio
49 ized endogenously presented targets on EBV B lymphoblastoid cell lines (BLCLs), but not peripheral bl
51 a demonstration, Epstein-Barr virus-infected lymphoblastoid cell lines (EBV-LCL) were isolated based
52 addition, human LRRK2 G2019S patient-derived lymphoblastoid cell lines (LCL) demonstrated increased m
53 l transcriptomics data from a panel of human lymphoblastoid cell lines (LCL) to infer drug response n
54 tore iNKT recognition in EBV-infected cells, lymphoblastoid cell lines (LCL) were treated with AM580,
57 ntly reported gene expression changes in 480 lymphoblastoid cell lines (LCLs) after in vitro simvasta
58 lysis of RNA stability in seven human HapMap lymphoblastoid cell lines (LCLs) and analyzed the effect
59 lomere repeat elements (SREs) in transformed lymphoblastoid cell lines (LCLs) and human embryonic ste
60 otein isoforms across 68 Yoruba (YRI) HapMap lymphoblastoid cell lines (LCLs) and identified 12 cis a
65 tosine modifications at 283,540 CpG sites in lymphoblastoid cell lines (LCLs) derived from independen
66 We developed an in vitro model of PMD with lymphoblastoid cell lines (LCLs) derived from participan
70 ene expression profiles using microarrays on lymphoblastoid cell lines (LCLs) from 413 cases and 446
71 romatin profiling for three histone marks in lymphoblastoid cell lines (LCLs) from 75 sequenced indiv
72 Previously we hypothesized that a subset of lymphoblastoid cell lines (LCLs) from children with auti
73 Here we analyze m(6)A mRNA modifications in lymphoblastoid cell lines (LCLs) from human, chimpanzee
74 enome-wide association studies involving 523 lymphoblastoid cell lines (LCLs) from individuals of Eur
75 A21 to assess trisomic protein expression in lymphoblastoid cell lines (LCLs) from patients with DS a
77 B cell lymphoma infected with HHV-6B, (iii) lymphoblastoid cell lines (LCLs) from subjects with inhe
79 EBV to convert human B cells into long-lived lymphoblastoid cell lines (LCLs) in vitro requires the c
80 rther demonstrated that knockdown of H2AX in lymphoblastoid cell lines (LCLs) led to the upregulation
81 ion, elicited lytic EBV in latently infected lymphoblastoid cell lines (LCLs) partially via Toll-like
82 r Virus (EBV) conversion of B-lymphocytes to Lymphoblastoid Cell Lines (LCLs) requires four EBV nucle
83 hocytes (RBLs) leads to the establishment of lymphoblastoid cell lines (LCLs) that can grow indefinit
84 transformed into continuously proliferating lymphoblastoid cell lines (LCLs) that carry EBV DNA as e
87 between vitamin D receptor (VDR) binding in lymphoblastoid cell lines (LCLs), chromatin states in LC
92 amining Epstein-Barr virus (EBV)-transformed lymphoblastoid cell lines (LCLs), we identified four EBV
93 sforms B cells to continuously proliferating lymphoblastoid cell lines (LCLs), which represent an exp
106 a panel of iPSCs from 58 well-studied Yoruba lymphoblastoid cell lines (LCLs); 14 of these lines were
107 vitro results in their immortalization into lymphoblastoid cell lines (LCLs); this latency program i
108 loci in genome-wide expression data sets of lymphoblastoid cell lines (n = 1,830) and were related t
109 CAMKK2 in human brains (P=1.1 x 10(-6)) and lymphoblastoid cell lines (the lowest P=8.4 x 10(-6)).
110 ranscription initiation across several human lymphoblastoid cell lines (Yoruba population) and detect
112 eQTLs each affect hundreds of transcripts in lymphoblastoid cell lines across three African populatio
113 ong chromosomes from primary lymphocytes and lymphoblastoid cell lines adapted to long-term growth in
114 edish patients, and to KMO expression in 717 lymphoblastoid cell lines and 138 hippocampal biopsies.
115 s from human, chimpanzee, and rhesus macaque lymphoblastoid cell lines and compared them to transcrip
116 stimulation with autologous EBV-transformed lymphoblastoid cell lines and correlated with EBV load i
117 rm that CYFIP1 is upregulated in transformed lymphoblastoid cell lines and demonstrate its upregulati
118 R-181c, were significantly down-regulated in lymphoblastoid cell lines and fresh peripheral blood cel
119 990620, that differentially recruits CTCF in lymphoblastoid cell lines and human brain to influence C
121 hromatin signature to infer MAE for genes in lymphoblastoid cell lines and human fetal brain tissue.
123 with a decline in CLDN14 expression in both lymphoblastoid cell lines and T cells (Padj = 0.003 and
124 ic variation in TF binding affinity in human lymphoblastoid cell lines and test their association wit
125 med histone acetylation ChIP-seq on 57 human lymphoblastoid cell lines and used the resulting reads t
126 e associated with lower FBXO33 expression in lymphoblastoid cell lines and with reduced frontal gray
128 ng Salmonella typhimurium infection of human lymphoblastoid cell lines as a means of dissecting the g
130 nomic and transcriptomic data from 445 human lymphoblastoid cell lines by combining an RNA editing QT
131 ne expression levels generated for 373 human lymphoblastoid cell lines by the Geuvadis consortium and
132 virus (EBV) to transform human B cells into lymphoblastoid cell lines compared to that of type 2 EBV
133 us (EBV)-encoded RNAs (EBERs) were tested in lymphoblastoid cell lines containing EBER mutants of EBV
134 study the response to 23 treatments in three lymphoblastoid cell lines demonstrating that it should a
135 associations with gene expression levels in lymphoblastoid cell lines derived from 480 participants
136 onstructed by transferring mitochondria from lymphoblastoid cell lines derived from a Chinese family
137 generated by transferring mitochondria from lymphoblastoid cell lines derived from a Chinese family
138 icative impairments could be demonstrated in lymphoblastoid cell lines derived from affected individu
140 iated (P = .01) with FPGS gene expression in lymphoblastoid cell lines derived from combined HapMap A
141 , cytosine modification levels in 133 HapMap lymphoblastoid cell lines derived from individuals of Eu
142 ne expression in response to high glucose in lymphoblastoid cell lines derived from matched individua
143 We performed functional assays by using lymphoblastoid cell lines derived from members of Chines
144 expression by affecting the binding to GR in lymphoblastoid cell lines derived from the same patients
146 ar susceptibility to cisplatin in 176 HapMap lymphoblastoid cell lines derived from Yoruba individual
149 otein from V362I and R381Q variants in human lymphoblastoid cell lines exhibited lower expression lev
150 with reduced survival in a panel of 24 human lymphoblastoid cell lines exposed to the alkylating agen
151 Here, we show that EBV-immortalized FSHD lymphoblastoid cell lines express DUX4 and both early an
153 udies, we collected RNA-sequencing data from lymphoblastoid cell lines for 431 Hutterite individuals.
154 red the cytotoxicity of 156 compounds in 884 lymphoblastoid cell lines for which genotype and transcr
156 ne relative protein levels of 5,953 genes in lymphoblastoid cell lines from 95 diverse individuals ge
158 rometry to perform an integrated analysis in lymphoblastoid cell lines from a diverse group of indivi
159 itation, we derived normal and DNMT3A mutant lymphoblastoid cell lines from a germline mosaic individ
161 OGT protein levels was observed in isolated lymphoblastoid cell lines from affected individuals, con
162 This miniATM variant was also highlighted in lymphoblastoid cell lines from AT patients and was shown
163 f NK cells to kill freshly established human lymphoblastoid cell lines from autologous or allogeneic
164 and extended in three human EBV-transformed lymphoblastoid cell lines from individuals with MSS, lea
166 tein (FMRP), its upregulation in transformed lymphoblastoid cell lines from patients with duplication
172 in nonsynonymous substitutions in all three lymphoblastoid cell lines in our study, unlike RNA editi
174 of 237 up-regulated genes derived from FSHD lymphoblastoid cell lines is elevated in FSHD muscle bio
175 gh-throughput sequencing data sets for human lymphoblastoid cell lines mapped to the EBV genome.
177 elationship between COMETs and haplotypes in lymphoblastoid cell lines of African and European origin
178 lls or NK-cell clones with HLA-C2(+) CCR7(+) lymphoblastoid cell lines resulted in increased CCR7 upt
179 s, which leads to continuously proliferating lymphoblastoid cell lines through examination of the exp
180 red heteroplasmies in mtRNA from 446 human B-lymphoblastoid cell lines to their corresponding mtDNA u
181 logous dendritic cells and EBV-transformed B-lymphoblastoid cell lines transduced with an adenoviral
182 cellular phenotypes in three patient-derived lymphoblastoid cell lines with three variants: p.Gly535A
184 using >300 expression microarrays (from 117 lymphoblastoid cell lines) in corticosteroid (dexamethas
186 appear to regulate gene expression in human lymphoblastoid cell lines, a tightly controlled, largely
187 ells, HeLa cells, HEK293 cells, and 16 human lymphoblastoid cell lines, all genotyped for the 9p21.3
188 iP luciferase reporter, EBNA1 DNA binding in lymphoblastoid cell lines, and EBV genome number per lym
189 evel was performed using patient and control lymphoblastoid cell lines, and established experimental
190 ed BZLF1 expression in latently EBV-infected lymphoblastoid cell lines, and knockdown of BGLF2 reduce
191 n transcriptional response in fibroblast and lymphoblastoid cell lines, as well as circulating monocy
192 cific quantification assays to a panel of HD lymphoblastoid cell lines, each carrying the major Europ
193 measure chromatin accessibility in 70 Yoruba lymphoblastoid cell lines, for which genome-wide genotyp
194 h resulted in the generation of EBV-positive lymphoblastoid cell lines, indicating that the virus in
195 eral blood mononuclear cells, monocytes, and lymphoblastoid cell lines, leading to enhanced autophagi
196 nscription factor MEF2A in 32 distinct human lymphoblastoid cell lines, providing insights into the m
197 entified as eQTL in monocytes, liver tissue, lymphoblastoid cell lines, T cells, and fibroblasts are
199 nd drug sensitivity measurements in 24 human lymphoblastoid cell lines, was applied to a panel of 12
203 sed gene editing approach in MDV-transformed lymphoblastoid cell lines, we show that MDV-miR-M4, desp
204 to the establishment of permanently growing lymphoblastoid cell lines, whereas CD40L/IL-4 blasts hav
205 iation in genome-wide gene expression in 107 lymphoblastoid cell lines, with alleles ranging from 15
229 uencing in ATAC-seq libraries generated from lymphoblastoid cell lines: targeted cleavage of mitochon
230 n both peripheral blood leukocytes (PBL) and lymphoblastoid cell lines; and a study of postoperative
231 e method was first applied to RNA-Seq from a lymphoblastoid cell-line, achieving 99.7% precision and
235 hese cells do not resemble the proliferating lymphoblastoid cells (LCLs) (latency III) that are gener
237 acteristics of MMR-deficient tumor cells) in lymphoblastoid cells (LCs) from 3 patients with CMMRD an
238 strongly associated with CREB1 expression in lymphoblastoid cells (P<0.005) and the prefrontal cortex
239 in transfected murine macrophages and human lymphoblastoid cells affected anthrax toxin binding, int
242 Gene expression profiling was performed on lymphoblastoid cells and levels of CXCL10 were measured
243 F8 mRNA and intracellular FVIII protein in B lymphoblastoid cells and liver biopsies from individuals
244 ntagonizes the growth inhibitory effect in B lymphoblastoid cells and might be used to modulate the f
245 lular fusion transcripts in transduced human lymphoblastoid cells and primary hematopoietic stem/prog
247 cently demonstrated that SRS patient-derived lymphoblastoid cells are capable of transporting exogeno
249 NA from affected individuals' fibroblasts or lymphoblastoid cells confirmed mutant transcripts with p
254 and associated with PRPF6 mRNA expression in lymphoblastoid cells from 373 Europeans in the 1000 Geno
257 ce (MECP2-TG), and corrected MECP2 levels in lymphoblastoid cells from MECP2 duplication patients in
258 RNA and protein abundance in patient-derived lymphoblastoid cells from one NUDT21 deletion and three
260 of plasmid replication (oriP) as a "bait" in lymphoblastoid cells further confirmed contacts with act
261 ter irradiation are cell type-specific, with lymphoblastoid cells generally showing more contact chan
263 omatin conformation capture (Hi-C) assays in lymphoblastoid cells have become available, enabling us
264 we utilized gene expression association from lymphoblastoid cells lines from 754 p.Phe508del CF-affec
268 roarray analysis performed on FRDA patient's lymphoblastoid cells stably reconstituted with frataxin,
269 cleus cytome (CBMN-Cyt) assay with WIL2-NS B lymphoblastoid cells to test the potential genotoxicity,
270 peptide profile of human EC and syngeneic B lymphoblastoid cells was biochemically analyzed and comp
272 alleles in cells, irrelevant sera binding to lymphoblastoid cells were minimized by CRISPR/Cas9 elimi
274 ere readily detected in DNA from the treated lymphoblastoid cells, and both were largely eliminated f
275 MK) enzyme activity was analyzed in cultured lymphoblastoid cells, and mevalonic acid levels were mea
278 2-depleted motor neurons, in patient-derived lymphoblastoid cells, induced pluripotent stem cell-deri
279 ction studies in EBV-positive B lymphoma and lymphoblastoid cells, we found that the levels of functi
280 tructures (at the macrodomain resolution) of lymphoblastoid cells, we identify an atlas of stable int
282 NA and transcription factor targets in human lymphoblastoid cells, while being nearly a million times
288 s) and active regions of the human genome in lymphoblastoid cells.IMPORTANCE EBV is associated with ~
290 Global transcriptome analysis of L254F-OGT lymphoblastoids compared with controls revealed a small
292 ised myelogenous leukemia (K562) and healthy lymphoblastoid (GM12878) cell lines to train the learnin
296 histone modifications, cohesin, and CTCF in lymphoblastoid lines from 19 individuals of diverse ance
298 ng data for various cell nucleus geometries (lymphoblastoid, skin fibroblast, and breast epithelial c
299 virus-driven luciferase expression, or A3R5 lymphoblastoid target cells, in which infectivity was ev
300 obtain such transcriptomes, we sequenced the lymphoblastoid transcriptomes of three family members (G