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1 cleavage of the Pth substrates diacetyl-[14C]lysyl-tRNA and acetyl-[14C]phenylalanyl-tRNA.
2                                              Lysyl-tRNAs are essential for protein biosynthesis by ri
3                           However, decreased lysyl-tRNA(Lys) in the lysS mutant provides a possible r
4 tion during coded protein synthesis requires lysyl-tRNA(Lys), which is synthesized by lysyl-tRNA synt
5 resence of Nepsilon-(5-azido-2-nitrobenzoyl)-lysyl-tRNA, photoreactive lysine residues would be incor
6 ynthetases (LysRS1 and LysRS2) together form lysyl-tRNA(Pyl), a potential intermediate to pyrrolysyl-
7                     The Arabidopsis thaliana lysyl tRNA synthetase (AtKRS) structurally and functiona
8 inhibition of the Mycobacterium tuberculosis lysyl tRNA synthetase (LysRS).
9 RNA, we discovered that the Escherichia coli lysyl tRNA synthetase was responsible for misacylating t
10 ein A) and LysN (anticodon binding domain of lysyl tRNA synthetase).
11  stem eliminated misacylation by the E. coli lysyl tRNA synthetase, and led to the development of a f
12        Here, we examine an N(epsilon)-acetyl-lysyl-tRNA synthetase (AcKRS), which is polyspecific (i.
13 of fully modified cellular tRNALys3 by human lysyl-tRNA synthetase (h-LysRS).
14 hydrolyze lysyl-adenylate generated by human lysyl-tRNA synthetase (hLysRS) by proceeding through an
15                                        Human lysyl-tRNA synthetase (hLysRS) is essential for aminoacy
16                                        Human lysyl-tRNA synthetase (hLysRS), the only cellular factor
17 f the anticodon in tRNA recognition by human lysyl-tRNA synthetase (hLysRS).
18 is, p.Tyr173SerfsX7, and p.Ile302Met) in the lysyl-tRNA synthetase (KARS) gene in two patients from t
19                                              Lysyl-tRNA synthetase (KARS), an enzyme required for pro
20 cing, we discovered genetic abnormalities in lysyl-tRNA synthetase (KARS).
21 e identified at highly conserved residues of lysyl-tRNA synthetase (KARS): the c.1129G>A (p.Asp377Asn
22  some cases may be driven by the presence of lysyl-tRNA synthetase (KRS) in the medium.
23 an methionyl-tRNA synthetase (MRS) and human lysyl-tRNA synthetase (KRS) were expressed in human-deri
24      Yeast two-hybrid screens suggested that lysyl-tRNA synthetase (LysRS) also associates with LeuRS
25 s has been developed against M. tuberculosis lysyl-tRNA synthetase (LysRS) and cellular studies suppo
26 nscription primer via an interaction between lysyl-tRNA synthetase (LysRS) and the HIV-1 Gag polyprot
27 f the transcription factors MITF or USF2 and lysyl-tRNA synthetase (LysRS) are associated with human
28  into two unrelated structural classes, with lysyl-tRNA synthetase (LysRS) being the only enzyme repr
29  previously shown that the essential protein lysyl-tRNA synthetase (LysRS) exists in two unrelated fo
30                                        Human lysyl-tRNA synthetase (LysRS) is also specifically packa
31 unrelated aminoacyl-tRNA synthetase classes, lysyl-tRNA synthetase (LysRS) is the only example known
32                     The alpha(2) homodimeric lysyl-tRNA synthetase (LysRS) is tightly bound in the MS
33                Moreover, similarly disrupted lysyl-tRNA synthetase (LysRS) proteins showed reduced en
34                                              Lysyl-tRNA synthetase (LysRS), a class II enzyme whose m
35 s a mutation in the KARS gene, which encodes lysyl-tRNA synthetase (LysRS), a moonlight protein with
36 s a mutation in the KARS gene, which encodes lysyl-tRNA synthetase (LysRS), a moonlight protein with
37  Gag and GagPol, as well as host cell factor lysyl-tRNA synthetase (LysRS), are required for specific
38 horamidates and lysyl-adenylate generated by lysyl-tRNA synthetase (LysRS).
39 res lysyl-tRNA(Lys), which is synthesized by lysyl-tRNA synthetase (LysRS).
40    The crystal structure of the constitutive lysyl-tRNA synthetase (LysS) from Escherichia coli has b
41 lciparum has shown that cladosporin inhibits lysyl-tRNA synthetase (PfKRS1).
42                                              Lysyl-tRNA synthetase 1 (KARS1), an aminoacyl-tRNA synth
43  targeted the ATP-binding pocket of T. cruzi lysyl-tRNA synthetase 1 (KRS1).
44 o the production of a protein with canonical lysyl-tRNA synthetase activity in vitro.
45                                              Lysyl-tRNA synthetase aminoacylates CoA-SH with lysine,
46 69 base pair to G4:C69 and overproduction of lysyl-tRNA synthetase and methionyl-tRNA transformylase
47 jeK, encoding truncated homologs of class II lysyl-tRNA synthetase and of lysine-2,3-aminomutase, res
48 r results on recognition of tRNAs by E. coli lysyl-tRNA synthetase and on competition in cells among
49                                Two proteins, lysyl-tRNA synthetase and translocon-associated protein
50          Purified E. coli RNA polymerase and lysyl-tRNA synthetase are both capable of adding such 5'
51 blem, Hoepfner et al. uncover the parasite's lysyl-tRNA synthetase as a druggable target.
52 , our analysis points to the extant forms of lysyl-tRNA synthetase being preceded in evolution by the
53  significant similarity to any class II-type lysyl-tRNA synthetase could be detected.
54 lso encode G73, the motif 2 loop sequence of lysyl-tRNA synthetase differs at multiple positions from
55 r, the capacity of tRNA3Lys to interact with lysyl-tRNA synthetase does not entirely explain the enha
56                                              Lysyl-tRNA synthetase from Escherichia coli belongs to t
57                                  The genomic lysyl-tRNA synthetase gene consisted of 15 exons.
58 tely 30%, of the mature transcripts from the lysyl-tRNA synthetase gene.
59                     Two cDNAs encoding human lysyl-tRNA synthetase have been identified.
60            The detection of an archaeal-type lysyl-tRNA synthetase in B. burgdorferi and other pathog
61 udies have demonstrated that the presence of lysyl-tRNA synthetase in HIV-1 virions might account for
62  this knowledge gap, a diverse set of potent lysyl-tRNA synthetase inhibitors was profiled to identif
63                                              Lysyl-tRNA synthetase is a member of the class II aminoa
64                                        Human lysyl-tRNA synthetase is bound to the multi-tRNA synthet
65 ases, we report here that the class II human lysyl-tRNA synthetase is relatively insensitive to the n
66 d a trans pQTL relationship between the KARS lysyl-tRNA synthetase locus and levels of the DIDO1 prot
67     Crystals of the thermo-inducible E. coli lysyl-tRNA synthetase LysU which diffract to 2.1 A resol
68 nal modification with (R)-beta-lysine by the lysyl-tRNA synthetase paralog PoxA.
69                                   A putative lysyl-tRNA synthetase resistance gene was identified in
70 the sequence of the loop of motif 2 of human lysyl-tRNA synthetase specifies a structural variation t
71 syl-AMP generated by either E. coli or human lysyl-tRNA synthetase were partially transferable by C-t
72 ural classes, the only known exception being lysyl-tRNA synthetase which exists in both classes I (Ly
73 gene lies immediately adjacent to the cKARS (lysyl-tRNA synthetase) gene with the two genes in a head
74                                              Lysyl-tRNA synthetase, a class II enzyme, edits homocyst
75                                  We examined lysyl-tRNA synthetase, a close structural homologue of t
76 molar inhibitor of the Plasmodium falciparum lysyl-tRNA synthetase, and exhibits activity against bot
77 tion in the C. capitata lysine--tRNA ligase (Lysyl-tRNA synthetase, LysRS) gene responsible for the t
78 lysis of B. burgdorferi mRNA showed that the lysyl-tRNA synthetase-encoding gene is highly expressed,
79                        Expression of the two lysyl-tRNA synthetase-green fluorescent protein gene fus
80 base pair reduces mischarging by the E. coli lysyl-tRNA synthetase.
81 he synthesis of asparaginyl-tRNA and a novel lysyl-tRNA synthetase.
82 n shown to contain an unrelated class I-type lysyl-tRNA synthetase.
83 rgdorferi contains a functional class I-type lysyl-tRNA synthetase.
84 (Trp)(CCA) to be aminoacylated by A.thaliana lysyl-tRNA synthetase.
85 n the mammalian cells by S207-phosphorylated Lysyl-tRNA synthetase.
86                      They are synthesized by lysyl-tRNA synthetases (EC 6.1.1.6), a group of enzymes
87          Alternatively, class I and class II lysyl-tRNA synthetases (LysRS1 and LysRS2) together form
88                                              Lysyl-tRNA synthetases (LysRSs) are unique amongst the a
89           In bacteria and eukarya, all known lysyl-tRNA synthetases are subclass IIc-type aminoacyl-t
90                Thus, isoleucyl-, valyl-, and lysyl-tRNA synthetases behave as aminoacyl-S-CoA synthet
91                  This difference between the lysyl-tRNA synthetases of spirochetes and their hosts ma
92           Nonautoantigenic aspartyl-tRNA and lysyl-tRNA synthetases were not chemotactic.
93 ination factor Rho, bacterial and eukaryotic lysyl-tRNA synthetases, bacteriophage T4 endonuclease VI
94 RS1 and LysRS2, the two different M. barkeri lysyl-tRNA synthetases.
95 h lysine but is not closely related to known lysyl-tRNA synthetases.
96 bases indicated high homology to a family of lysyl-tRNA synthetases.
97 he amino acid level to archaeal class I-type lysyl-tRNA synthetases.