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1 pic glutamate receptors, mGluR1a, mGluR2, or mGluR8.
2 at, except for the mouse cDNA clone encoding mGluR8.
3 pha-methyl-amino-phosphonobutyrate inhibited mGluR8.
4 ng either mGluR4, mGluR8, or both mGluR4 and mGluR8.
5 xpress either group II mGluR2/3 or group III mGluR8.
7 analyzed the mechanism of action underlying mGluR8 activity and modulation of the cytosolic Ca2+ con
8 ated the biological effects of the selective mGluR8 agonist (S)-3,4-dicarboxyphenylglycine ((S)-3,4-D
9 by CIPN was significantly attenuated by the mGluR8 agonist, (S)-3,4-DCPG, the Group II mGluR agonist
10 results suggest that Group II mGluR agonist, mGluR8 agonist, and meclizine are promising candidates a
11 ng, which enables endocytosis and recycling, mGluR8 and beta-arr form stable complexes, which leads t
12 rents in Xenopus laevis oocytes coexpressing mGluR8 and G protein-coupled inwardly rectifying potassi
13 ing male and female mice to test agonists of mGluR8 and Group II mGluR as well as meclizine as interv
16 gh percentage of single-labeled mGluR2/3 and mGluR8 cells, there is a considerable population of doub
18 pression, with 75.0% of DRG cells expressing mGluR8, followed by group II, with 51.6% expressing mGlu
19 ic glutamate receptor (mGluR), type 8 mGluR (mGluR8), has been identified functionally as a presynapt
24 localization of the group III mGluR subtype, mGluR8, in the human body and investigated the biologica
27 role for mGluR8 in anxiety and suggest that mGluR8 may not be a therapeutic target for schizophrenia
30 These results suggest that the function of mGluR8 of modulating the cytosolic Ca2+ concentration an
33 glutamate activates presynaptic mGluR2/3 and mGluR8 receptors but not mGluR4, although this receptor
34 fficking, including the identification of an mGluR8 splice variant with impaired internalization.
35 nputs from glutamatergic ON bipolar cells at mGluR8 synapses, and excitatory inputs from an OFF wide-
37 bands, corresponding to sublaminae 1-4; and mGluR8 was localized in two broad bands, one each in the