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1 roduction of multiple proteins from a single mRNA transcript.
2 of two or more somatic variants on the same mRNA transcript.
3 equence-specific recognition of the targeted mRNA transcript.
4 ne target, IFIT1/ISG56, by destabilizing its mRNA transcript.
5 all copies of miR-200c bound the immobilized mRNA transcript.
6 oRNAs and alternative polyadenylation of the mRNA transcript.
7 trin mRNA splicing and creating an elongated mRNA transcript.
8 thway leading to destabilization of the NOXA mRNA transcript.
9 ed nonsense-mediated decay of the respective mRNA transcript.
10 e with a sequence complementary to the Smad7 mRNA transcript.
11 the predicted effects on splicing of the pre-mRNA transcript.
12 tive splicing of its single gene-encoded pre-mRNA transcript.
13 sense RNAs or untranslated regions (UTRs) of mRNA transcripts.
14 However, they tended to have much longer pre-mRNA transcripts.
15 ibosomes are not uniformly distributed along mRNA transcripts.
16 hundreds to thousands of both noncoding and mRNA transcripts.
17 able change in the relative amounts of viral mRNA transcripts.
18 native polyadenylation to produce at least 8 mRNA transcripts.
19 ative polyadenylation to generate at least 8 mRNA transcripts.
20 resolution method for analysis of 5' ends of mRNA transcripts.
21 with fast translation initiation on nascent mRNA transcripts.
22 maintenance of normal levels of overlapping mRNA transcripts.
23 es simultaneously via the abundance of their mRNA transcripts.
24 ed a global survey of the decay rates of MTB mRNA transcripts.
25 rescued upon overexpression of human C9orf72 mRNA transcripts.
26 use recombinant sclerostin decreased cyp27B1 mRNA transcripts.
27 al capping of RNA polymerase II (Pol II) pre-mRNA transcripts.
28 in the relative abundance of DLL1 and LRIG1 mRNA transcripts.
29 essing small RNAs derived from processing of mRNA transcripts.
30 amounts of IFNgamma, T-bet, and IL-15Ralpha mRNA transcripts.
31 ncing (RNA-Seq) were used to identify CYP3A4 mRNA transcripts.
32 Polyadenylation sites mark the ends of mRNA transcripts.
33 ites allows a single gene to encode multiple mRNA transcripts.
34 ted novel approach for targeted reduction of mRNA transcripts.
35 ted KSPGs (lumican and keratocan), and their mRNA transcripts.
36 iptionally regulate the expression of target mRNA transcripts.
37 ed human immunodeficiency virus type 1 viral mRNA transcripts.
38 tors interact at cis regulatory sites on pre-mRNA transcripts.
39 A detection feasible down to ~600 individual mRNA transcripts.
40 he regulation, initiation, and processing of mRNA transcripts.
41 2 and RARA by reducing m(6)A levels in these mRNA transcripts.
42 nnotated, and now includes the major spliced mRNA transcripts.
43 n to include 10 374 novel lncRNAs and 58 640 mRNA transcripts.
44 rgeting nirK, typical nosZ and atypical nosZ mRNA transcripts.
45 gene expression up to 2-fold at the level of mRNA transcripts.
46 ignaling pathways, proteolysis products, and mRNA transcripts.
47 untranslated regions (UTR) of messenger RNA (mRNA) transcripts.
48 ukin-2(IL-2), IL-4, and IL-10 messenger RNA (mRNA) transcripts.
49 scriptome studies involve the examination of mRNA transcript abundance and gene expression patterns i
50 ociated with alterations in DNA copy number, mRNA transcript abundance and splicing, and both inter-
53 d bead-enhanced detection of three different mRNA transcripts, achieving a dynamic range spanning ove
54 as carried out combining proteomics, qRT-PCR mRNA transcripts analysis, and enzyme activities assessm
55 ike particles (VLPs) package the recombinant mRNA transcript and can be disassembled and reassembled
56 lineage tracing studies, spatially specific mRNA transcript and protein expression, and single-cell
57 expression through stabilisation of the vacA mRNA transcript and that the stabilising effect is of pa
58 li: the number of protein molecules made per mRNA transcript and the number of ribosomes required per
59 2 and CLN3 lead to a significant decrease in mRNA transcripts and a corresponding decrease in protein
60 uplex RNAs recruit argonaute 2 (AGO2) to pre-mRNA transcripts and altered splicing requires AGO2 expr
62 educed expression of Bdnf exon IV-containing mRNA transcripts and BDNF protein in the cerebral cortex
64 ed miR-146a to its multiple predicted target mRNA transcripts and found that miR-146a was predicted t
65 ene regulation, where they act by binding to mRNA transcripts and inhibiting their translation (i.e.
67 RNA surveillance system is active on all pre-mRNA transcripts and modulated by nutrient availability.
68 vels of TGF-beta1, IL-6, IL-23, and IL-1beta mRNA transcripts and of TGF-beta1, IL-6, and IL-1beta pr
69 3H14 modulates pre-mRNA processing of select mRNA transcripts and plays a critical role in regulating
70 elative to B cells, but hnRNPLL binds Ighg2b mRNA transcripts and promotes an increase in levels of t
71 usly that human endogenous retroviral (HERV) mRNA transcripts and protein are found in cells of HIV-1
72 moral artery significantly upregulates mDia1 mRNA transcripts and protein in the injured vessel, part
73 ICH3 gene functionally and identified ERICH3 mRNA transcripts and protein isoforms that are highly ex
74 tin, leptin receptor (long isoform), and PTH mRNA transcripts and protein were detected in an overlap
76 stimulation leads to destabilization of TNF mRNA transcripts and subsequent failure to produce TNF p
77 -beta1, TGF-beta2, IL-6, IL-23, and IL-1beta mRNA transcripts and TGF-beta1, IL-6, and IL-1beta prote
78 duces transition from short to fully spliced mRNA transcripts and that this transition is blocked by
79 the 3'-untranslated region (UTR) of several mRNA transcripts and the eukaryotic initiation factor 4G
80 AtpA and AtpD, are translated from the same mRNA transcript, and both contain a PPG motif; however,
81 n within the coding region of the associated mRNA transcript, and enhances its translation by relievi
82 tion was observed among DNA copy number, the mRNA transcript, and protein expression of the HER-2 gen
83 IL-1beta, TNF-alpha, and cathepsin S (Ctss) mRNA transcripts, and greater nitrotyrosine and 4-hydrox
89 Overall, these results suggest that sperm mRNA transcripts are indicators of low dose toxicant-ind
92 ies to date have explored whether particular mRNA transcripts are more critical than others in facili
95 A) in a surface RNA polymerase reaction; the mRNA transcripts are then translated into proteins by ce
97 cused on developing RNA flow cytometry using mRNA transcripts as proxies distinguishing NKG2C from NK
98 antification of both high- and low-abundance mRNA transcripts, as well as micro-RNAs that are not eas
99 polyadenylation to generate full-length B19V mRNA transcripts at levels sufficient to support product
100 ved RNA surveillance mechanism through which mRNA transcripts bearing premature termination codons (P
101 l and can also alter the reading frame in an mRNA transcript because 1,N (6)-erA is incompletely inci
102 precursors encoded in open-reading frames of mRNA transcripts but also cryptic peptides encoded in ap
104 t the absolute quantification of single-cell mRNA transcripts by digital, one-step reverse transcript
105 ound to both enhance the binding kinetics of mRNA transcripts by disrupting complex secondary structu
108 nderstand gene function, the encoding DNA or mRNA transcript can be manipulated and the consequences
111 oduction of noncanonical and cancer-specific mRNA transcripts, can lead to loss-of-function in tumor
112 man patients with ARDS, inflammasome-related mRNA transcripts (CASP1, IL1B, and IL18) were increased
114 ase in IL-1beta, IFN-gamma, MHC II, and Ctss mRNA transcripts compared with young wild-type mice and
115 NAs (ceRNAs) sequester microRNAs to regulate mRNA transcripts containing common microRNA recognition
116 decay is involved in the degradation of CLN1 mRNA transcripts containing the p.R151X mutation in huma
117 cluding endorepellin, were present; however, mRNA transcripts corresponding to regions of domain III
118 re identified with retained introns in their mRNA transcripts, corresponding with a significant reduc
119 gions of interest containing combinations of mRNA transcripts, CpG sites, and SNPs by jointly testing
120 ing to full-length and alternatively spliced mRNA transcripts, decreasing mRNA levels across the life
121 ed Cx43 protein levels due to decreased GJA1 mRNA transcripts dependent upon beta-catenin transcripti
122 report the alternative splicing of the TRPC3 mRNA transcript (designated TRPC3c), resulting in omissi
123 tial expression of a Y-chromosome associated mRNA transcript, Eif2s3y, and the X-linked, X-inactivati
124 -splicing events, resulting in at least nine mRNA transcripts encoding at least 12 functionally diffe
125 cal to generating appropriate levels of B19V mRNA transcripts encoding capsid proteins and small nons
129 a more than 10(3)-fold increase in exosomal mRNA transcripts, even from cells with low basal levels
132 CagA contributes to the DNA copy change and mRNA transcript expression of the HER-2 gene and, conseq
133 vance of SPAG5 gene copy number aberrations, mRNA transcript expression, and protein expression and a
135 , with global upregulation of immune-related mRNA transcripts following infection and comparatively m
136 the gene fused to a 3' tag that targets the mRNA transcript for degradation by the host nonsense-med
137 ained more intensely and exhibited increased mRNA transcripts for both proteins compared to those in
138 Real-time polymerase chain reaction detected mRNA transcripts for Dra and Slc26a6 in mouse incisor en
139 hown that Type I-III BNSTALG neurons express mRNA transcripts for each of the Kv4 alpha subunits.
140 cription factor, and RORgammat and increased mRNA transcripts for IL-23 receptor (IL-23R) and IL-26,
141 in reaction (scRT-PCR) studies revealed that mRNA transcripts for Kv4.2, Kv4.3, and all four KChIPs w
142 s from psoriasis patients revealed increased mRNA transcripts for several members of this RTK family
143 r lung, as determined by increased levels of mRNA transcripts for the keratinocyte-derived chemokine,
148 cess that creates translatable mitochondrial mRNA transcripts from cryptogene encoded RNAs and is uni
149 lates the expression of numerous alternative mRNA transcripts from genes involved in synaptic plastic
153 cing generates a diversity of messenger RNA (mRNA) transcripts from a single mRNA precursor and contr
156 n of the main open reading frame (ORF) in an mRNA transcript has been reported to be regulated by ups
157 tion of full-length capsid proteins encoding mRNA transcripts, has been suggested as a step that bloc
158 genome-wide studies of alternatively spliced mRNA transcripts have become increasingly important in c
160 be associated with reduced expression of BLK mRNA transcript in human B cell lines; however, little i
161 hic factor (BDNF) gene generates a truncated mRNA transcript in naive brain that is suppressed upon c
164 viously focused on the detection of aberrant mRNA transcripts in a subset of disorders for which RNA
165 idization technique to visualize HIV gag-pol mRNA transcripts in cerebellum and lymph node tissues fr
167 to examine expression of alternative CYP3A4 mRNA transcripts in hepatocytes in response to developme
171 dium channel alpha subunits revealed NaV 1.7 mRNA transcripts in nearly all retrogradely labelled col
172 r-1a, -1b, -2a, -2b, -2f, and -2g; and Tg1-1 mRNA transcripts in ocular surface tissues increased in
175 constructs designed to induce expression of mRNA transcripts in trans with respect to the SSA system
176 One approach is to label newly synthesized mRNA transcripts in vivo through the incorporation of mo
179 criptomics, measures the expression level of mRNAs (transcripts) in a given cell population at a spec
180 a role for MRB1590 in editing mitochondrial mRNA transcripts, in particular the transcript encoding
181 the targeted degradation of stored maternal mRNA transcripts including sirtuin 1 and ubiquitin prote
183 s and is required for translation of complex mRNA transcripts, including those encoding key cell-cycl
184 recently described assay, aberrantly spliced mRNA transcripts initiated in the vector A2UCOE sequence
187 is processed from the ubiquitous hnRNP K pre-mRNA transcript, is achieved by inhibition of its biogen
189 bsequent allosteric conformational switch on mRNA transcript length has not yet been investigated.
190 of thermoregulation resulting in lower eftM mRNA transcript level at 37 degrees C compared to 25 deg
191 lation of NnCYP76B6 resulted in reduction of mRNA transcript levels as well as CPT content in compari
192 nCYP76B6 showed a significant enhancement in mRNA transcript levels coincident with enhanced CPT accu
196 ta1 and FOXM1 expression at both protein and mRNA transcript levels in ERalpha-positive breast cancer
197 mokine receptor 1 [duffy blood group]) whose mRNA transcript levels in plasma exosomes significantly
199 overexpressions mediated distinct effects on mRNA transcript levels of fibrillar procollagens, their
203 and SMART-seq, can reveal simultaneously the mRNA transcript levels of thousands of genes in thousand
206 of WsMYC2 showed significant enhancement of mRNA transcript levels which corroborated well with the
209 understanding of an important enzyme in the mRNA transcript life cycle and allow functional analogie
210 ncertainties about the complete structure of mRNA transcripts limit the progress of research in this
211 ges to DJ-1 were concomitant with changes in mRNA transcripts mainly involved in catecholamine metabo
213 re, while the C-terminal half encoding viral mRNA transcript modifications consists of a flexible app
214 ls (669 U/mL vs. 106 U/mL, P = 0.01), higher mRNA transcript numbers of thymic stromal lymphopoietin
218 of predicting the risk for AMR by measuring mRNA transcripts of AMR-associated genes in plasma exoso
223 that RNAi reagents designed to suppress the mRNA transcripts of the same gene often produce a spectr
224 idization to examine the distribution of the mRNA transcripts of these genes in the apteronotid telen
225 y score for EoE, p(EoE), based on esophageal mRNA transcript patterns from biopsies of patients with
229 ino antisense oligonucleotide prevented B19V mRNA transcripts polyadenylated at the (pA)d site during
230 he generation of a sufficient number of B19V mRNA transcripts polyadenylated at the distal polyadenyl
231 149 synthetic genetic interactions, and 225 mRNA transcripts (primarily consisting of stress- and nu
233 le, as well as monitoring the number of lacI mRNA transcripts produced in the presence and absence of
236 th CTDs and subsequently analyzed esophageal mRNA transcript profiles in patients with EoE with or wi
239 se to hypoxic stress and stabilizes the PIM1 mRNA transcript, resulting in PIM1 protein overexpressio
240 ession of gene products via hybridization to mRNA transcripts, resulting in suppression of translatio
243 dicts splice junctions from an arbitrary pre-mRNA transcript sequence, enabling precise prediction of
244 appear to decrease the half-life of the tra mRNA transcript, suggesting that RteR does not bind to t
246 al (NS) gene of influenza A virus encodes an mRNA transcript that is alternatively spliced to express
247 8 (NS) of the influenza virus genome encode mRNA transcripts that are alternatively spliced to expre
248 n by RNA Polymerase II and completion of pre-mRNA transcripts that are dependent on hormone signaling
249 eavage and polyadenylation (ApA) to generate mRNA transcripts that differ in the lengths of their 3'
250 t in E. coli most translation occurs on free mRNA transcripts that have diffused into the ribosome-ri
251 to be RAG-mediated, and are associated with mRNA transcripts that initiate from 3' regions of Notch1
252 region (UTR) truncation of growth-promoting mRNA transcripts that relieves intrinsic microRNA- and A
253 gene expression profiling failed to identify mRNA transcripts that were differentially regulated by t
255 proach does not require amplification of the mRNA transcript, thereby allowing for simplified analyse
256 partially complementary sequences on target mRNA transcripts, thereby causing their degradation, dea
257 en microRNAs (miRNAs) and the messenger RNA (mRNA) transcripts they regulate, and thereby often fail
258 s RNA binding proteins are deposited onto an mRNA transcript to modulate post-transcriptional process
259 to recognize active Polymerase II-derived TE mRNA transcripts to both trigger and correctively reesta
262 ent strategy for the analysis of full length mRNA transcripts using arrays of silicon photonic micror
263 The expression of multiple IGF1 or Igf1 mRNA transcript variants in human and mouse skeletal mus
265 yed higher levels of Abca1, Abcg1, and Pparg mRNA transcripts versus Ager-expressing Ldlr(-/-) mice i
266 Nrf2 was markedly enhanced, the level of its mRNA transcript was barely changed in the fat-1 transgen
269 ge of long reads spanning the full length of mRNA transcripts, we provide support for 23,865 splice i
271 Overall 1479 lncRNA transcripts and 1109 mRNA transcripts were aberrantly expressed in 6- and 20-
272 escue assay, and demonstrated that all three mRNA transcripts were able to rescue abcc6a morpholino-i
276 a CMV promoter to drive expression of IL-37, mRNA transcripts were not present in colons at the resti
277 ression of COL I and lower expression of OCN mRNA transcripts were noted in the PDL-MSCs compared to
279 ) subsets by using immunohistochemistry, and mRNA transcripts were quantified by using a microarray.
280 of paraffin-embedded tissue was isolated and mRNA transcripts were quantified with real-time polymera
284 the resolution reaction, approximately 1,500 mRNA transcripts were significantly different from place
287 ischer 344 rats identified 128 altered sperm mRNA transcripts when compared to control using linear m
288 ar reprogramming, including the induction of mRNA transcripts which encode anti-inflammatory cytokine
289 on by inhibiting polyadenylation of selected mRNA transcripts, which prevents binding of the ribosome
290 sed the expression of IL-1beta and TNF-alpha mRNA transcripts, while decreasing the frequency of CD45
291 ear the 3' end of a pre-mRNA create multiple mRNA transcripts with different 3' untranslated regions
295 For example, therapies targeting specific mRNA transcripts with splice-site-directed oligonucleoti
296 ternative polyadenylation (APA) and generate mRNA transcripts with varying lengths, typically of the
297 nse showed modulation of approximately 7,500 mRNA transcripts, with high expression of cytokines that
298 first time, the presence of RSV proteins and mRNA transcripts within BAL and blood neutrophils from i
299 al = 13.7 mug/L) altered the abundance of 26 mRNA transcripts within the liver of exposed pre-metamor
300 RNA targets from three different full length mRNA transcripts yielded a approximately 10 pM LOD with