ライフサイエンスコーパス: major disease

1 aquaphilic vehicle for Old World Leishmania major disease.

2 icin and paromomycin alone for ulcerative L. major disease.

3 substantially decrease the incidence of this major disease.

4 GPCRs) are important therapeutic targets for major diseases.

5 an counter to declining mortality from other major diseases.

6 f three medications that are used to prevent major diseases.

7 herapeutics for cost-effective treatments of major diseases.

8 due to their central role in the etiology of major diseases.

9 development of targeted therapies for these major diseases.

10 reducing mortality and disability from most major diseases.

11 of homocysteine are associated with several major diseases.

12 s an important therapeutic target in several major diseases.

13 ation of the adaptive immune system and many major diseases.

14 Bone metastasis in cancer patients is a major disease advancement for various types of cancer.

15 Bacterial meningitis remains a major disease affecting children in Cote d'Ivoire.

16 COVID-19 while concurrently addressing other major diseases affecting children in African countries.

17 The major diseases affecting the aorta are aortic aneurysms

18 Gut microbiota has been implicated in major diseases affecting the human population and has al

19 ng DPB1 allele, *0201, does not seem to be a major disease allele.

20 dy was to quantify the risk of mortality and major diseases among migrants during the 1991-2001 Balka

21 Mutations of mtDNA cause major disease and disability with a wide range of presen

22 Anxiety disorders constitute a major disease and social burden worldwide; however, many

23 view of twin concordance and discordance for major diseases and mental disorders, which conveys a cru

24 an wars faced considerably elevated risks of major diseases and mortality in their first decade in Sw

25 Many Gram-negative bacteria that cause major diseases and mortality worldwide require the type

26 tes pharmacological potential in the cure of major diseases and numerous biotechnological application

27 he potential for prevention and treatment of major diseases and potentially therapeutic regeneration

28 ive against strains that are associated with major diseases and resistant to multiple drugs could be

29 man genetic factors, the risks of developing major diseases and the molecular basis of drug efficacy

30 Virus encephalitis is a major disease, and alphaviruses, as highlighted by the r

31 an initiative to resolve disputed origins of major diseases, and a global early warning system to mon

32 ening disease (Huanglongbing, HLB) and other major diseases, and cold tolerance.

33 t causality and mechanisms linking these two major diseases are lacking.

34 ative capabilities of complement, highlights major disease areas with known complement contribution,

35 Recent findings in four major disease areas, inflammation, cancer, infection, an

36 ete revascularization with one graft to each major diseased artery system; 2) functional complete rev

37 rized by a FitzGibbon A-quality graft to the major diseased artery, and there were no new postanastom

38 erstanding and characterization of these two major diseases as well as their associated viruses and w

39 f its pathogenesis through identification of major disease associated pathways-knowledge that has the

40 Heart disease and cancer are the 2 major diseases associated with mortality risk in the Uni

41 ar cells from individuals homozygous for the major disease-associated L1007fsinsC NOD2 mutation respo

42 n trafficking and surface expression are the major disease-associated mechanisms associated with path

43 ses of T cell clones that are specific for a major disease-associated peptide to antigen-pulsed intac

44 TAR DNA binding protein 43 (TDP-43) is a major disease-associated protein involved in the pathoge

45 nity-dwelling adults aged >=70 years without major diseases at baseline.

46 ria before the present conflict and is now a major disease burden among 3.6 million Syrian refugees i

47 NAFLD is a major disease burden and a foremost cause of chronic liv

48 d with oncogenic papilloma viruses, remain a major disease burden in the absence of effective impleme

49 Itch represents a major disease burden of psoriasis.

50 ion of the aero-digestive tract represents a major disease burden of the elderly, and despite recent

51 epithelial lining and are associated with a major disease burden.

52 Lung cancer and chronic lung diseases impose major disease burdens worldwide and are caused by inhale

53 ill help understand and hopefully fight this major disease by generating general knowledge about canc

54 ive protein (CRP) concentration with risk of major diseases can best be assessed by long-term prospec

55 At present, several major disease categories (including but not limited to a

56 origin and divided their diagnoses into 125 major disease categories (of which 94 were complete-case

57 evolving brain asymmetry within subjects to major disease categories across ~4500 total medical diag

58 oint prevalence figures for each of the five major disease categories are comparable with those from

59 ation studies, identify CNVs associated with major disease categories, and illustrate the pleiotropic

60 We uncover CNV associations with four major disease categories, including autoimmune, cardio-m

61 were 36 histopathological diagnoses in seven major disease categories.

62 PM2.5 exposure and hospital admissions for 7 major disease categories: (1) endocrine, nutritional, an

63 The two major disease-causing biotypes of Vibrio cholerae, class

64 as an oligogenic inheritance with RET as the major disease-causing gene, while CIPO is genetically he

65 perates in intact Plasmodium falciparum, the major disease-causing human malaria parasite.

66 lalanine residue in Yor1p, equivalent to the major disease-causing mutation in CFTR, causes ER retent

67 The major disease-causing mutation in the cystic fibrosis tr

68 equence of six strains representing the five major disease-causing serotypes of Streptococcus agalact

69 ne showed consistent efficacy independent of major disease characteristics.

70 States during the period 1959-1999 for four major disease classes.

71 Hierarchical clustering yielded four major disease clusters: cluster 1 included all CIN3 hist

72 l of 67272 US female nurses who were free of major disease completed detailed questionnaires on diet

73 Major disease complications include thrombosis and leuke

74 e independence of others, that are linked to major disease components.

75 Obesity is a major disease condition, in turn leading to pathological

76 weighted sum of polygenic risk scores for 20 major disease conditions, including, e.g., coronary arte

77 ly known to be related to mortality and four major diseases contributing to mortality, to develop a l

78 atoria, X. vesicatoria and X. gardneri, is a major disease, contributing to significant yield losses

79 Major disease-control programs have greatly reduced both

80 Age-specific mortality rates from major diseases declined once population changes were acc

81 survival motor neuron) is thought to be the major disease determining gene since it is missing in th

82 clinical disease severity comprising of four major disease domains (seizure, cognitive failure, muscu

83 , somatic CAG repeat expansion, which is the major disease driver in HD, was significantly decreased

84 recruited monocyte-derived macrophages were major disease drivers by producing most IFN-beta, reside

85 alpha (HNF4a) and systemic inflammation are major disease drivers of AH.

86 whether T cell responses to neoepitopes are major disease drivers that could impact prediction, prev

87 llular processes and have been identified as major disease drivers, activation and termination of PLC

88 ations deal with RNA viruses associated with major disease emergence events, such as HIV-1, influenza

89 We selected long-term studies that assessed major disease end points as an outcome.

90 garding the effect of periodontal therapy on major disease endpoints such as tooth loss, edentulism,

91 hat iNTS has gained greater recognition as a major disease entity in children younger than 5 years.

92 on age and sex, polygenic risk scores for 22 major diseases explained less than 2 percentage points o

93 This review presents the major disease features and treatments of these forms of

94 SCA7(140Q/5Q) males and females exhibit the major disease features observed in patients, including c

95 ncreased the risks of death overall and from major diseases for men in China.

96 One of the major diseases for which early diagnosis is crucial is r

97 of the peripheral nervous system and is the major disease gene for the rare congenital breathing dis

98 assessed in Cox models providing overall and major disease-group incidence rate ratios (IRRs).

99 Several major diseases have been associated with length variatio

100 Cercospora leaf spot (CLS) is a major disease impacting global sugar beet cultivation an

101 d the gut microbiome differences across five major diseases in a multi-cohort dataset constituting mo

102 the fungus Hemileia vastatrix, is one of the major diseases in coffee throughout the world.

103 phylum of intracellular parasites that cause major diseases in humans and animals and are evolutionar

104 hosts by blood-sucking arthropods and cause major diseases in humans and animals.

105 ure on the development of the microbiome and major diseases including allergy and infection in large

106 modulator of human health and the status of major diseases including cancer, diabetes and inflammato

107 Mycobacteria cause major diseases including human tuberculosis, bovine tube

108 on during pregnancy predisposes offspring to major diseases, including hypertension, in later life, b

109 are associated with reduced risk of several major diseases, including neurodegenerative disorders.

110 is of granulomas is linked to progression of major diseases, including tuberculosis and atheroscleros

111 enes and that autoimmunity to CII is not the major disease-inducing event.

112 This review for residents discusses the major diseases involving the mesenteric small bowel and

113 rone, and plasma renin activity, are the two major diseases linked so far to mutations in a Kir chann

114 the TTN (titin gene), titin has emerged as a major disease locus for cardiac disorders.

115 C1 gene on human chromosome 18, which is the major disease locus.

116 Major disease manifestations include fatal acute infecti

117 Shifts in major diseases may have significant implications regardi

118 macological therapies for RP must target the major disease mechanism and contend with overlap, if it

119 f T(reg)-mediated immunosuppression is not a major disease mechanism in AA.

120 ew that defective protein glycosylation is a major disease mechanism in gerodermia osteodysplastica.

121 in haploinsufficiency has been proposed as a major disease mechanism.

122 One of the major disease mechanisms in FTDP-17 is the increased inc

123 pies of the null allele, excluding CNTF as a major disease modifier in ALS.

124 proteins and explored its utility to predict major disease morbidity and mortality in diverse populat

125 canker, caused by Neonectria ditissima, is a major disease of apple (Malus x domestica) with limited

126 t (CLS), caused by Cercospora beticola, is a major disease of Beta vulgaris worldwide.

127 Bovine tuberculosis (bTB) is a major disease of cattle in the UK, placing a significant

128 Malaria is a major disease of humans caused by protozoan parasites fr

129 by the fungus Colletotrichum sublineola is a major disease of sorghum worldwide.

130 One major disease of the elderly is Parkinson's disease, whi

131 ed by Puccinia graminis f. sp. tritici) is a major disease of wheat.

132 tential pharmacological targets to treat the major diseases of aging.

133 We review the major diseases of bone remodeling, emphasizing our curre

134 Many major diseases of human brain involve deficiencies of se

135 Recent research suggests that several of the major diseases of later life, including coronary heart d

136 proteins, but whether fungi, which cause the major diseases of most crop species, also require differ

137 ty to acquire new information) is one of the major diseases of our era.

138 Thus far, there are two major diseases of programmed cell death associated with

139 Aortic aneurysm and dissection (AAD) are major diseases of the adult aorta caused by progressive

140 range of preclinical strategies for tackling major diseases of the nervous system, the clinical limit

141 Many of the major diseases of Western populations are hormone depend

142 the virus is endemic and continues to cause major disease outbreaks every year.

143 ough HCM may progress along 1 or more of its major disease pathways (i.e., arrhythmic sudden death ri

144 A major disease phenotype in patients with LEOPARD syndrom

145 They do not display the major disease phenotypes of lpr and IL-2 KO mice.

146 Peritonitis is the major disease problem of laying hens in commercial table

147 Pathological LN status is a major disease prognostic factor and marker of surgical q

148 ce prevented EAE, suggesting that IL-17 is a major disease-promoting factor.

149 Here, we report a major disease-promoting role for microRNA-92a (miR-92a)

150 Recently, the major disease protein found in the pathological inclusio

151 TAR DNA-binding protein 43 (TDP-43) is a major disease protein in amyotrophic lateral sclerosis (

152 er was unknown, we showed that TDP-43 is the major disease protein in both disorders.

153 TDP-43 is the major disease protein in ubiquitin-positive inclusions o

154 ed to assess current methods of managing the major diseases related to hepatic dysfunction in pregnan

155 and controls) FDG-PET dataset extracted two major disease-related metabolic components: (a) a nonspe

156 Cultivated and wild potatoes contain a major disease-resistance cluster on the short arm of chr

157 and leucine-rich-repeat proteins (NLRs), the major disease-resistance gene families, has been unexplo

158 ed at diagnosis, the reliable achievement of major disease responses makes extensive BM testing and M

159 related multimorbidity, aging biomarkers and major disease risk factors.

160 re young adults (median age, 22 years) whose major disease risk was residence in population-dense cen

161 enting infection of the oviduct and thus the major disease sequelae associated with chlamydial infect

162 While the major disease signs and lesions of type C disease are us

163 While the major disease signs and lesions of type D animal disease

164 y developed countries and remains one of the major diseases strongly affected by the diet.

165 samples, including BC organoids covering all major disease subtypes (triple-negative, estrogen recept

166 defined as the labile copper pool, occurs in major diseases such as cancer, where tumor growth and me

167 survival, and imbalances are associated with major diseases such as cancer.

168 olds tremendous promise for the treatment of major diseases such as cancer.

169 st has broad application to the treatment of major diseases such as diabetes and a wide range of othe

170 ans have provided unambiguous evidence for a major disease susceptibility locus on chromosome 6p21 (P

171 acterial blight of rice (Oryza sativa L.), a major disease that constrains production of this staple

172 g these drugs that demonstrate reductions in major diseases that treatment of hypertension is intende

173 rdered proteins are closely linked with many major diseases, their binding mechanisms with small mole

174 Tuberculosis continues to be a major disease threatening millions of lives worldwide.

175 s endemic in Asia, with live bird trade as a major disease transmission pathway.

176 tivation of CO(2)-detecting neurons in three major disease-transmitting mosquitoes: Anopheles gambiae

177 ent in disease; 2) they are enriched in many major disease types like hematopoietic diseases, cardiov

178 therapy will be enabled for a wide range of major diseases using genomic knowledge alone.

179 phylogeny that resolves the position of the major disease vector species and the major mosquito line

180 ation in Aedes sierrensis, a congener of the major disease vector species that experiences large ther

181 ovel cuticular resistance mechanisms in this major disease vector.

182 Mosquitoes are major disease vectors because most species must feed on

183 ars of potential life lost for SCD and other major diseases were compared.