ライフサイエンスコーパス: malate

1 by DcuABC in exchange for L-aspartate and L-malate.

2 s enhancing nocturnal CO2 fixation to stored malate.

3 ary RCH were treated with systemic sunitinib malate.

4 ylated sugar intermediates and of starch and malate.

5 rticularly the roles of starch, sucrose, and malate.

6 nce via a novel mechanism involving sinapoyl malate.

7 xpress the ME genes and is unable to utilize malate.

8 t, followed by the binding of oxaloacetate/L-malate.

9 building up the ester side chain to sinapoyl malate.

10 I) reduction in the presence of tartrate and malate.

11 ven glucose and pyruvate but normalized with malate.

12 cretion of organic acids such as citrate and malate.

13 apillary RCH treated with systemic sunitinib malate.

14 ncluding citrate, isocitrate, succinate, and malate (1.4-3.9-fold).

15 cbl1 plants exudated less Al-chelating malate, accumulated more Al, and displayed a severe root

16 These perturbations paralleled reduced malate accumulation at dawn and decreased nocturnal star

17 Malate accumulation in the vacuole largely determines ap

18 logical traits and drought-induced nighttime malate accumulation was observed across genotypes.

19 optimizing CAM-associated dark CO2 fixation, malate accumulation, CAM productivity, and core circadia

20 y, dark period CO(2) fixation, and nocturnal malate accumulation.

21 ctivated malate transporter 12 (ALMT12) is a malate-activated, voltage-dependent member of the alumin

22 The increased longevity provided by malate addition did not occur in fumarase (fum-1), glyox

23 Malate also increased NADPH, NAD, and the NAD/NADH ratio

24 VHL) disease treated with systemic sunitinib malate, an agent that inhibits both anti-vascular endoth

25 Ultraviolet spectroscopy of sinapoyl malate, an essential UV-B screening agent in plants, was

26 med) are 2.73 for oxidation of pyruvate plus malate and 1.64 for oxidation of succinate.

27 reduced Km [PEP] coupled with elevated I50 [malate and Asp] values) via in vivo deubiquitination of

28 ppc2 mutant greatly reduced the synthesis of malate and citrate and severely suppressed ammonium assi

29 h the PEP carboxylase competitive inhibitors malate and diethyl oxalacetate (DOA) in the strong isopr

30 Both malate and DOA did not alter the sensitivity of isoprene

31 Malate and fumarate addition increased oxygen consumptio

32 ls and nitrate, increased levels of sucrose, malate and fumarate and minor changes in total protein a

33 tribute to the lifespan extension induced by malate and fumarate by increasing the amount of oxidized

34 previously with an impaired accumulation of malate and fumarate in leaves.

35 lacking AtQUAC1 accumulated higher levels of malate and fumarate.

36 upplying the ppc1/ppc2 mutant with exogenous malate and glutamate, suggesting that low nitrogen statu

37 malate importer, ABCB14, increases both its malate and its background auxin transport activity, sugg

38 y DcuABC-mediated import and conversion of L-malate and L-aspartate.

39 Malate and lactate dehydrogenases (MDH and LDH) are homo

40 Lactate levels, lactate/malate and lactate/pyruvate ratios were elevated in HKCs

41 pression of maeP and maeE is induced by both malate and low pH, and induction in response to both cue

42 Some metabolites, such as malate and Man, appeared in the models for both conducta

43 Additional structures of the complex with malate and of the apo form of GlcB supported that hypoth

44 ially NADPH-producing pathways involving (S)-malate and ornithine, quorum sensing, sporulation, and c

45 n of RsbU revealed that alpha-ketoglutarate, malate and oxaloacetate bound to the RsbU periplasmic do

46 d is its catalysis of the interconversion of malate and oxaloacetate in the tricarboxylic acid cycle.

47 ine, aspartate, cysteine, glutamine, lysine, malate and pyroglutamate.

48 Malate and pyruvate were diverted to produce aspartate,

49 LND inhibits the formation of fumarate and malate and suppresses succinate-induced respiration of i

50 quently, this oxaloacetate is converted into malate and then pyruvate, ostensibly increasing the NADP

51 ng its sensitivity to feedback inhibition by malate and thus enhancing nocturnal CO2 fixation to stor

52 three different substrates (L(+)-tartrate, D-malate, and 3-isopropylmalate).

53 gulatory mechanism of BdALMT12 activation by malate, and Ca(2+)/CaM, emphasizing that a complex regul

54 of 19 traits, including sucrose, ascorbate, malate, and citrate levels.

55 tes including alpha-KG, succinate, fumarate, malate, and citrate were observed in TGF-beta1-different

56 ally relevant concentrations of pyruvate and malate, and flux of respiration, NAD(P)H fluorescence, a

57 ncomitant accumulation of the MDH substrate, malate, and fumarate, its immediate precursor in the Kre

58 itrate, 2-oxoglutarate, succinate, fumarate, malate, and oxaloacetate) were tested for their influenc

59 riptan, eletriptan hydrobromide, almotriptan malate, and rizatriptan benzoate tablets.

60 ull assimilatory flux to produce glyoxylate, malate, and succinate.

61 n rates in response to glutamate, but not to malate, and were depleted in all TCA cycle substrates be

62 s cell system confirmed that this channel is malate- and voltage-dependent.

63 ral function affording bacterial growth on D-malate as a carbon source, the D-malate dehydrogenase of

64 sIII, and is required for normal growth with malate as a sole carbon source.

65 umarate, so conversion of this metabolite to malate as detected by (13)C-magnetic resonance spectrosc

66 displayed lower production of aspartate and malate, as well as reduced k(pyr->asp) and (13)C-label e

67 (LDH) reaction and the intermediates of the malate-aspartate and glycerol 3-phosphate shuttles.

68 ism by which GOT2 acetylation stimulates the malate-aspartate NADH shuttle activity and oxidative pro

69 ere we find that the absence of a functional malate-aspartate NADH shuttle caused by aralar/AGC1 disr

70 mitochondria, is the regulatory step in the malate-aspartate NADH shuttle, MAS.

71 d increases the expression of glycolysis and malate-aspartate shuttle (MAS) genes.

72 r Aralar/AGC1 (Slc25a12), a component of the malate-aspartate shuttle (MAS), is stimulated by modest

73 Here, we studied the role of malate-aspartate shuttle (MAS)-dependent substrate suppl

74 sport mechanisms with consequent compromised malate-aspartate shuttle and changes in allosteric effec

75 mplex I of the electron transport chain, the malate-aspartate shuttle and mitochondrial citrate expor

76 relies on shuttle mechanisms, including the malate-aspartate shuttle and the glycerol-3-phosphate sh

77 t a profound reliance on glucose metabolism, malate-aspartate shuttle deregulation leads to a specifi

78 The malate-aspartate shuttle is indispensable for the net tr

79 The malate-aspartate shuttle is operated by two pairs of enz

80 nd that mitochondrial citrate export and the malate-aspartate shuttle promote histone acetylation, an

81 Hyperacetylation of mitochondrial malate-aspartate shuttle proteins impaired the transport

82 drogenase (MDH) operate as components of the malate-aspartate shuttle, in which a reducing equivalent

83 These findings support a model in which the malate-aspartate shuttle, mitochondrial citrate export a

84 GOT2, a member of the malate-aspartate shuttle, plays an essential role in the

85 partate/glutamate carriers is central to the malate-aspartate shuttle, urea cycle, gluconeogenesis an

86 Reduced levels of aspartate deregulated the malate-aspartate shuttle, which is important for cytopla

87 itochondrial transporter that is part of the malate-aspartate shuttle, which regulates the NAD+/NADH

88 ate carrier 1 (AGC1), a key component of the malate-aspartate shuttle.

89 ons, is the regulatory component of the NADH malate-aspartate shuttle.

90 eotide breakdown and partial reversal of the malate/aspartate shuttle.

91 he restoration of respiration with glutamate/malate back to control levels.

92 catalyze the oxidative decarboxylation of D-malate-based substrates with various specificities.

93 The broader role of a malate/beta-methylmalate synthase in human physiology an

94 We report that CLYBL encodes a malate/beta-methylmalate synthase, converting glyoxylate

95 oascorbic (DHAA) acids and validated in 20mM malate buffer (pH 3.8).

96 studied: calcium carbonate, calcium citrate malate, calcium phosphate and calcium bisglycinate.

97 Malate can be synthesized from fumarate by the enzyme fu

98 haliana Our results also show that exogenous malate can rescue the long-root phenotype of lpi5 and lp

99 olonization assays to describe how aspartate/malate can trigger initial Salmonella Typhimurium gut-lu

100 lling the production of organic acid anions (malate, citrate) that are excreted in copious amounts by

101 hat chemically reduce iron(III) from citrate-malate complexes.

102 e roots constitutively and had 2-fold higher malate concentrations in the xylem sap than nulls, indic

103 3)C-label exchange rate between pyruvate and malate, consistent with down-regulated gluconeogenesis.

104 We demonstrate that fruit citrate and malate contents have been impacted by selection during d

105 esent bioinformatic data suggesting that the malate cycle may support phosphoglycolate salvage in div

106 that an oxidative pathway, which we term the malate cycle, supports phosphoglycolate salvage.

107 The alternative malate decarboxylase, NADP-ME, did not appear to compens

108 During the light period, malate decarboxylation concentrates CO(2) around Rubisco

109 Q2: Do the enzymes responsible for malate decarboxylation limit daytime mobilisation from t

110 ) catalyze two key steps during light-period malate decarboxylation that underpin secondary CO(2) fix

111 The kinetics of malate dehydrogenase (MDH) catalyzed oxidation/reduction

112 Two isoenzymes of malate dehydrogenase (MDH) operate as components of the

113 hosphate, reduced are used by NADP-dependent malate dehydrogenase (MDH) to reduce OAA to malate, thus

114 Malate dehydrogenase (MDH), a key enzyme in the tricarbo

115 tes aggregation of model substrates, such as malate dehydrogenase (MDH), and inhibits disaggregation

116 atured substrates such as alpha-lactalbumin, malate dehydrogenase (MDH), and the beta-subunit of ATP

117 MDH2 encodes mitochondrial malate dehydrogenase (MDH), which is essential for the c

118 peroxisomal NADH is reoxidised to NAD(+) by malate dehydrogenase (Mdh3p) and reduction equivalents a

119 Mitochondrial malate dehydrogenase (mMDH; EC 1.1.1.37) has multiple ro

120 as activated primary T cells, that cytosolic malate dehydrogenase 1 (MDH1) is an alternative to LDH a

121 X5 (PEX5C) receptor construct or peroxisomal malate dehydrogenase 1 (pMDH1) cargo protein into sunflo

122 d in cell-cell contacts) and MDH1 (cytosolic Malate dehydrogenase 1), revealed their role in early st

123 led to increased nitrogen assimilation, NADP-malate dehydrogenase activation, and light vulnerability

124 No malate dehydrogenase activity was detected using macerat

125 urs of NMP with URC, including mitochondrial malate dehydrogenase and glutamic-oxaloacetic transamina

126 n into two target proteins (Escherichia coli malate dehydrogenase and human histone H3) caused homoge

127 alanine amino transferase and glutamate and malate dehydrogenase and malate, there are no links betw

128 cytochrome-C) and others (creatine kinase M, malate dehydrogenase cytosolic, fibrinogen and parvalbum

129 HG is generated by lactate dehydrogenase and malate dehydrogenase in response to hypoxia.

130 growth on D-malate as a carbon source, the D-malate dehydrogenase of Escherichia coli (EcDmlA) natura

131 The heat-denatured malate dehydrogenase that did not refold by the assistan

132 trate channeling (e.g., of oxaloacetate from malate dehydrogenase to citrate synthase), and use of al

133 rase and further oxidized to oxaloacetate by malate dehydrogenase with the accompanying reduction of

134 ctor protein (SteA), and a metabolic enzyme (malate dehydrogenase), and demonstrate practical applica

135 ycle components, including citrate synthase, malate dehydrogenase, and aconitase, resulted in a one-c

136 the metabolic enzymes citrate synthase (CS), malate dehydrogenase, and strombine dehydrogenase remain

137 d interfacial residues between mitochondrial malate dehydrogenase, citrate synthase, and aconitase we

138 es with isolated lactate dehydrogenase-1 and malate dehydrogenase-2 revealed that generation of 2-HG

139 d two key enzymes-glycerol dehydrogenase and malate dehydrogenase-were overexpressed to improve PA ti

140 hose substrates include the short-lived Mdh2 malate dehydrogenase.

141 nzymes with multiple isoforms, aconitase and malate dehydrogenase.

142 tamate oxaloacetate transaminases (GOT), and malate dehydrogenases (MDH).

143 nd MDH2 encoding mitochondrial and cytosolic malate dehydrogenases, respectively; and (iv) GLN1 encod

144 Lifespan extension induced by malate depended upon the longevity regulators DAF-16 and

145 )-ATO and Mito(10)-ATO inhibit both pyruvate/malate-dependent complex I and duroquinol-dependent comp

146 Nicotiana benthamiana cells, Ma1 mediates a malate-dependent inward-rectifying current, whereas the

147 e substrates between alpha-ketoglutarate and malate despite high rates of glutaminolysis, as determin

148 ion during therapy, treatment with sunitinib malate did not improve visual acuity or reduce the size

149 Despite these conditions, sinapoyl malate displays anomalous spectral broadening extending

150 that increasing OsALMT4 expression affected malate efflux and compartmentation within the tissues, w

151 Q3: Does malate efflux from the vacuole set the pace of decarboxy

152 ing the membrane permease ALMT1, to increase malate exudation in response to low phosphate.

153 cue the long-root phenotype of lpi5 and lpi6 Malate exudation is required for the accumulation of Fe

154 o underlie Arabidopsis Al tolerance via root malate exudation, known as SENSITIVE TO PROTON RHIZOTOXI

155 However, the rapid clearance of Sunb-malate eye drops administered through topical instillati

156 culates as ferric complexes with citrate and malate (Fe(III)3Cit2Mal2, Fe(III)3Cit3Mal1, Fe(III)Cit2)

157 ed included: iron complexes with citrate and malate: Fe(III)(Cit)(3)(Mal), Fe(III)(Cit)(2)(Mal)(2), F

158 Malate feeding resulted in the inhibition of net assimil

159 We detected signals from fumarate and malate following intravenous administration of hyperpola

160 e suture-induced corneal NV than either Sunb-malate free drug or the placebo MS.

161 anion channel responsible for the release of malate from guard cells, is essential for efficient stom

162 The active endobacterium likely extracted malate from the fungal host as the primary carbon substr

163 e lines overexpressing (OX) OsALMT4 released malate from the roots constitutively and had 2-fold high

164 of various metabolites including sucrose and malate (from several potential sources; including guard

165 schemia, PTP opening may result in succinate/malate-fueled ROS production from complex III due to act

166 ariation in several metabolite pools such as malate, fumarate or citrate, and flux calculations sugge

167 ne), tricarboxylic acid cycle intermediates (malate, fumarate), glutamate, fatty acid acylcarnitines,

168 sensitivity, including alpha-ketoglutarate, malate, fumarate, succinate, 2-hydroxyglutarate, citrate

169 ome metabolites, including Glc-6-P, Fru-6-P, malate, fumarate, Xyl, and ribose.

170 gen flux after the addition of glutamate and malate (GM), adenosine diphosphate (d), succinate (S) an

171 trate, isocitrate and the two enantiomers of malate have been studied by (1)H NMR titration experimen

172 ntrations of citrate, and to a lesser extent malate, have a major impact on nucleus-encoded transcrip

173 lts of this study collectively indicate that malate importantly controls the chloroplast reductive st

174 Introduction of this D/E-P motif into malate importer, ABCB14, increases both its malate and i

175 ive cardiac means to replenish succinate and malate in MS.

176 nulls, indicating greater concentrations of malate in the apoplast.

177 e CO(2) via an organic intermediate, such as malate in the case of C(4) CCMs).

178 the reversible oxidative decarboxylation of malate in the presence of NADP.

179 , KCS combinations of glutamate, citrate and malate increased PFP (from 1.22 to 1.29 mmol peroxides/k

180 ges in isoprene emission rate in control and malate-inhibited leaves were associated with changes in

181 Malate inhibition of isoprene emission was associated wi

182 convert the C4-dicarboxylates aspartate and malate into fumarate (AspA, FumABC), are required for fu

183 nt analyses of doubly tagged, doubly charged malate ions.

184 Malate is a central metabolite involved in a multiplicit

185 Cabozantinib S-malate is a vascular endothelial growth factor receptor

186 sides the active site, where the substrate S-malate is bound bidentate to the unique iron of the [4Fe

187 The role of sinapoyl malate is confirmed through the use of a mutant compromi

188 or carbonyl carboxylates, such as tartrate, malate, lactate, pyruvate, and mandelate, significantly

189 The oxaloacetate is converted to malate, leading to malic acid accumulation in the vacuol

190 e calli results in a significant decrease in malate level.

191 h was coordinated predominantly by phosphate/malate ligands.

192 We developed Sunb-malate loaded poly(D,L-lactic-co-glycolic acid) (PLGA) m

193 at night for the mesophyll to fix CO(2) into malate (Mal) and store it in the vacuole.

194 Systemic sunitinib malate may be useful in slowing progression of ocular di

195 in this small series, and systemic sunitinib malate may not be safe for treatment of RCH when used at

196 ains predicted to impact the activity of the malate metabolic pathway.

197 Kok break point is also probably related to malate metabolism, which participates in maintaining pho

198 lly rate-limiting steps underpinning diurnal malate mobilisation and help direct future research effo

199 ion of CO(2) via RuBisCo dictate the rate of malate mobilisation?

200 ght-time primary carboxylation reactions and malate movement across the tonoplast.

201 Sunb-malate MS following SCT injection more effectively suppr

202 unb-malate through the SCT injection of Sunb-malate MS mitigated the proliferation of vascular endoth

203 Subconjunctival (SCT) injection of Sunb-malate MS provided a prolonged ocular drug retention and

204 Sunb-malate MS sustained the drug release for 30 days under t

205 -co-glycolic acid) (PLGA) microspheres (Sunb-malate MS) with a particle size of approximately 15 mum

206 greatly neutralized by SCT injection of Sunb-malate MS.

207 ose, lactate, alanine, glycerol 3-phosphate, malate, myo-inositol, or stearic acid tissue concentrati

208 l b, fructose, fumarate, glucose, glutamate, malate, nitrate, starch, sucrose, total amino acids, and

209 he dark or in nonphotosynthetic tissues, the malate-OAA shuttle was proposed to be mediated by the co

210 ivery pathways to the bundle sheath (BS; via malate or aspartate), and rates of phosphoglyceric acid

211 the predominance of Mn(II), bound mostly to malate or citrate, in roots and stems of all four specie

212 mulated in vacuoles as either soluble Mn(II) malate or citrate.

213 ochondria (n = 7) for glycolysis (pyruvate + malate)- or FA (palmitoylcarnitine)-derived substrates,

214 bution of isotopes when (13)C-glucose, (13)C-malate, or (13)C-pyruvate was provided as a substrate to

215 ure following incubation with abscisic acid, malate, or citrate.

216 ase, converting glyoxylate and acetyl-CoA to malate, or glyoxylate and propionyl-CoA to beta-methylma

217 in lipid vesicles catalyzed the exchange of malate, oxaloacetate, and aspartate for phosphate plus a

218 graphic analyses with succinate, fumarate, L-malate, oxaloacetate, pyruvate and D- and L-2HG support

219 duction-oxidation (redox) homeostasis is the malate-oxaloacetate (OAA) shuttle.

220 ase (MDH) catalyzed oxidation/reduction of L-malate/oxaloacetate is pH-dependent due to the proton ge

221 found that in glucose grown cells, both the malate/oxaloacetate shuttle and a glycerol-3-phosphate d

222 alents are transferred to the cytosol by the malate/oxaloacetate shuttle.

223 required for expression of genes encoding a malate permease (maeP) and malic enzyme (maeE).

224 A malate-phosphate anti-porter DctA is regulated by RpoN a

225 hydrogen peroxide emission using pyruvate + malate (PM) or succinate + rotenone (SR) as substrates.

226 ing in increased [(13)C]-glucose flux toward malate production, potentially explaining the susceptibi

227 ing to cytosolic glucose carbon flow via OAA-malate-pyruvate and acetyl-CoA-fatty acid pathways in TR

228 First, expression of the putative malate-pyruvate NADH shuttle increases in ssy5Delta cell

229 Here, we investigate the staphylococcal malate-quinone and l-lactate-quinone oxidoreductases (Mq

230 We solved the structure of a malate racemase apoprotein and used it, along with the p

231 We discovered two malate racemases, one phenyllactate racemase, one alpha-

232 s known regarding the drivers behind diurnal malate remobilisation from the vacuole that liberates CO

233 In the presence of malate, RoxS transiently escapes from repression by the

234 ALMT and AtMATE, responsible for citrate and malate secretion, respectively, were elevated under Ga s

235 atives most closely associated with sinapoyl malate showing characteristic broadening even under jet-

236 ngstrom crystal structure of MatC with bound malate shows a high level of substrate coordination, wit

237 Particularly, the citrate-malate shuttle supplies cytosolic acetyl-CoA and plastid

238 ralar deficiency, presumably through citrate-malate shuttle.

239 racteristics brought on by the electron-rich malate side chain.

240 altered as reflected by increased nighttime malate, starch, and glutathione levels and a reduced res

241 induced changes in amino acids, fumarate and malate, suggesting Krebs cycle up-regulation.

242 Sunitinib malate (Sunb-malate) targeting against multiple receptor

243 Malate supplementation did not extend the lifespan of lo

244 We have used a fragment-based approach on malate synthase (GlcB) from Mycobacterium tuberculosis a

245 Here, we report that malate synthase (MS), the second enzyme of the glyoxylat

246 lidated the increase in isocitrate lyase and malate synthase activities.

247 as an essential physiologic function of Mtb malate synthase and advances its validation as a target

248 tudy the genes encoding isocitrate lyase and malate synthase from Chlorogloeopsis fritschii PCC 9212

249 g pathway of an 82-kDa slow folding protein, malate synthase G (MSG), was investigated.

250 anscript abundances for isocitrate lyase and malate synthase increased, and C. fritschii grew faster,

251 When the genes encoding isocitrate lyase and malate synthase were expressed in Synechococcus sp. PCC

252 glyoxylate shunt genes (isocitrate lyase and malate synthase) was >300-fold higher in the light--but

253 orted the activities of isocitrate lyase and malate synthase, the key enzymes of the glyoxylate cycle

254 Malate synthases are best known for their established ro

255 Sunitinib malate (Sunb-malate) targeting against multiple receptor tyrosine kin

256 showed a stronger interaction with dianionic malate than with the trianionic citrate or isocitrate, s

257 conversion of hyperpolarized oxaloacetate to malate, the two signal components are separated into com

258 Sunb-malate, the water-soluble form of sunitinib, was shown t

259 e and glutamate and malate dehydrogenase and malate, there are no links between single enzyme activit

260 in hydroponics but, when combined with 1 mm malate, this concentration inhibited growth.

261 Local sustained release of Sunb-malate through the SCT injection of Sunb-malate MS mitig

262 malate dehydrogenase (MDH) to reduce OAA to malate, thus regenerating the electron acceptor NADP.

263 rgillus carbonarius, AcDct(p), increased the malate titer 12-fold without affecting the growth.

264 the malic enzyme (ME) pathway, which allows malate to be used as a supplemental carbon source for gr

265 H), which is essential for the conversion of malate to oxaloacetate as part of the proper functioning

266 carboxylases that catalyse the conversion of malate to pyruvate and are essential for NADPH regenerat

267 fumarate with a progressive increase in the malate-to-fumarate (MA/FA) ratio at days 2 to 5 after so

268 indicating that ma1 has significantly lower malate transport activity than Ma1.

269 This study reveals new links between malate transport and mineral nutrition.

270 hat the truncation of Ma1 to ma1 reduces its malate transport function by removing a conserved C-term

271 Vacuolar malate transport has been characterized at the molecular

272 ON RHIZOTOXICITY1 (STOP1)-ALUMINUM-ACTIVATED MALATE TRANSPORT1 (ALMT1) signaling module was tested th

273 anion flux through plant aluminium-activated malate transporter (ALMT) proteins is activated by anion

274 RHIZOTOXICITY (STOP1) and ALUMINUM ACTIVATED MALATE TRANSPORTER 1 (ALMT1), represent a critical check

275 The aluminum-activated malate transporter 12 (ALMT12) is a malate-activated, vo

276 e-dependent member of the aluminum-activated malate transporter family that has been implicated in an

277 nts degradation of the yflS mRNA, encoding a malate transporter.

278 m genes, including carbonic anhydrases and a malate transporter.

279 unction analysis is shown using the aluminum malate transporter1 gene.

280 identification of ALMT4 (ALUMINUM ACTIVATED MALATE TRANSPORTER4) as an Arabidopsis thaliana ion chan

281 on of Ma1, an ortholog of ALUMINUM-ACTIVATED MALATE TRANSPORTER9 (ALMT9) in Arabidopsis (Arabidopsis

282 Aluminum-activated malate transporters (ALMTs) form a family of anion chann

283 The aluminum-activated malate transporters (ALMTs) form a membrane protein fami

284 of plastid-cytosol and mitochondrion-cytosol malate transporters in recycling the ammonia liberated d

285 sophyll of isozymes implicated in starch and malate turnover are discussed in line with the contrasti

286 Furthermore, malate uptake and utilization contribute to the adaptive

287 o S. pyogenes' carbon source repertory, that malate utilization is a highly regulated process, and th

288 Additionally, malate utilization requires the PTS transporter EI enzym

289 s suggest that other mechanisms, such as the malate valve and the Mehler reaction, were able to maint

290 Hence, the chloroplast malate valve and triose phosphate-3-phosphoglycerate shu

291 glucose, fructose, sucrose, starch, citrate, malate, vitamin C and soluble and insoluble oxalic acid.

292 e, induced by exogenous Ca(2+) ionophore and malate, was shown to be inhibited by exogenous applicati

293 ntration, in the presence of L-carnitine and malate, were performed.

294 n 2-day hypoxia and is mediated by cytosolic malate whereas in 10-day hypoxia the rewiring is mediate

295 o the active mechanism intrinsic to sinapoyl malate, which is tentatively attributed to mixing of the

296 with acetyl coenzyme A (acetyl-CoA) to give malate, which undergoes two oxidative decarboxylation st

297 ich a reducing equivalent is transported via malate, which when oxidized to oxaloacetate, transfers a

298 er, our results indicate that MDH1 generates malate with carbons derived from glutamine, thus enablin

299 protein from this system, binds to l- and d-malate with K(d) values of 27 and 21 nM, respectively, t

300 p. palustris, grew photoheterotrophically on malate without electron acceptors or H2 production.