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1 ier (BTB) of contraceptive drugs or to treat male infertility.
2 tis in ZFP628-deficient mice that results in male infertility.
3 o undergo normal differentiation, leading to male infertility.
4 including obesity, retinal degeneration and male infertility.
5 ntegration into microsurgical procedures for male infertility.
6 luences 4.1G function and is associated with male infertility.
7 f 4.1G in B6-129 hybrids was associated with male infertility.
8 Catpser3; depletion of late spermatids; and male infertility.
9 n, central nervous system abnormalities, and male infertility.
10 for loss of some of these proteins in human male infertility.
11 ance of the abnormal DNA repair mechanism in male infertility.
12 ian families segregating autosomal-recessive male infertility.
13 eiotic division, resulting in cell death and male infertility.
14 t lack of Spem1 causes sperm deformation and male infertility.
15 of which have been previously implicated in male infertility.
16 ccumulation of mucus in the sinus cavity and male infertility.
17 iple components of capacitation resulting in male infertility.
18 o-pulmonary disease, laterality defects, and male infertility.
19 er and viability) and increased incidence of male infertility.
20 ophthalmoparesis (SANDO), Parkinsonism, and male infertility.
21 ents that disrupt its activity could lead to male infertility.
22 s for another type of skeletal dysplasia and male infertility.
23 hagun, that is affected by both dwarfism and male infertility.
24 A number of recessive autosomal genes cause male infertility.
25 nctional analysis and molecular diagnosis of male infertility.
26 the long arm of the human Y chromosome cause male infertility.
27 s a rare but surgically correctable cause of male infertility.
28 exclusively in the testis and implicated in male infertility.
29 culatory duct obstruction is a rare cause of male infertility.
30 lications for neurodegenerative diseases and male infertility.
31 ociated with human neurological problems and male infertility.
32 ent and our understanding of the etiology of male infertility.
33 receptors may be useful in the treatment of male infertility.
34 implications for the understanding of human male infertility.
35 ate cancer, benign prostatic hyperplasia and male infertility.
36 contribute to some forms of human idiopathic male infertility.
37 f spermatogenesis are common causes of human male infertility.
38 gulating this process might help in treating male infertility.
39 era of considerable improvements in treating male infertility.
40 low blood pressure, kidney dysfunctions, and male infertility.
41 ated using a retroviral gene-trap system for male infertility.
42 pancreatitis resemble those associated with male infertility.
43 eficiency and identifies a treatable form of male infertility.
44 like autosomal) genes may be determinants of male infertility.
45 n some familial cases of autosomal recessive male infertility.
46 a novel therapeutic opportunity for treating male infertility.
47 provide a candidate locus for some cases of male infertility.
48 (MMAF) has been identified as a sub-type of male infertility.
49 and distinguish clinically distinct forms of male infertility.
50 n the aetiology, diagnosis, and treatment of male infertility.
51 en disrupted in mice, causes azoospermia and male infertility.
52 piRNA biogenesis, spermatogenic arrest, and male infertility.
53 e methods and detecting causes of idiopathic male infertility.
54 es of obstructive azoospermia found in human male infertility.
55 ildland fire smoke with a heightened risk of male infertility.
56 in post-meiotic defects, abnormal sperm, and male infertility.
57 hibit impaired sperm flagellum formation and male infertility.
58 um, is the most common identifiable cause of male infertility.
59 e linked to compromised sperm production and male infertility.
60 variant as a high-penetrance risk factor for male infertility.
61 t77F loading, abnormal sperm morphology, and male infertility.
62 the diagnosis and treatment of the causes of male infertility.
63 ght into the application in the treatment of male infertility.
64 this gene is a possible cause of idiopathic male infertility.
65 our understanding of the molecular basis of male infertility.
66 n mammalian spermatozoa and its relevance to male infertility.
67 permatogenesis in men, ultimately leading to male infertility.
68 potential therapeutic insights for treating male infertility.
69 tions worldwide and has been associated with male infertility.
70 cting sperm function during the diagnosis of male infertility.
71 ncompatibility of recombination hotspots and male infertility.
72 ould contribute to advances in therapies for male infertility.
73 a deficiency leads to testicular atrophy and male infertility.
74 hat cause defective transposon silencing and male infertility.
75 ts in mice including female subfertility and male infertility.
76 itourinary birth defects and their impact on male infertility.
77 could apply to treatment of disease such as male infertility.
78 d severe differentiation defects, leading to male infertility.
79 nd its loss results in neurodegeneration and male infertility.
80 h causes a number of side effects, including male infertility.
81 of the first meiotic division, resulting in male infertility.
82 set of candidate genes associated with moss male infertility.
83 oxiredoxins (PRDXs) is associated with human male infertility.
84 d decreased motility, resulting in selective male infertility.
85 CCP5 deficiency does cause male infertility.
86 al examination are essential in diagnosis of male infertility.
87 genetic defects are directly responsible for male infertility.
88 mosome gene, are an important cause of human male infertility.
89 disease progression and link SMN to general male infertility.
90 drogen receptor gene in PM cells resulted in male infertility.
91 cue sperm function in certain cases of human male infertility.
92 s ranging from a lack of testis formation to male infertility.
93 found that deletion of Mkrn2 in mice led to male infertility.
94 s meiotic recombination, leading to profound male infertility.
95 ns for the diagnosis and management of human male infertility.
96 t STAG3 is a strong candidate gene for human male infertility.
97 uld hypothesized its putative involvement in male infertility.
98 linical biomarker and therapeutic target for male infertility.
99 Oligo- and azoospermia are severe forms of male infertility.
100 and testicular macrophages that may lead to male infertility.
101 xic to the maturing spermatozoa resulting in male infertility.
102 it is a candidate to exert a causal role in male infertility.
103 evel in spermatozoa could be used to predict male infertility.
104 with acute and chronic prostatitis linked to male infertility.
105 ronic airway disease, laterality defects and male infertility.
106 as a diagnostic marker for the evaluation of male infertility.
107 ized by recurrent respiratory infections and male infertility.
108 ause of defective sperm function in cases of male infertility.
109 pe resulting from deletion of Ppp1cc gene is male infertility.
110 ERalpha AF-1 is capable of rescuing AF2ERKI male infertility.
111 underlying cause of many cases of idiopathic male infertility.
113 is, and mice with inactivated Pde11a exhibit male infertility, a known testicular germ cell tumor (TG
114 level of evidence for being associated with male infertility according to the ClinGen criteria, maki
116 lysis remains the cornerstone for evaluating male infertility, advanced diagnostic tests to investiga
119 transposons, followed by cell death, causing male infertility and a complete block of spermatogenesis
120 mans, defective ciliary motility can lead to male infertility and a congenital disorder called primar
123 o mutations play an important role in severe male infertility and explain a portion of the genetic ca
124 at the absence of beta4B-tubulin resulted in male infertility and failure to produce sperm cells.
126 ications for improving clinical diagnoses of male infertility and identifying additional targets for
127 lood-based tests useful in the management of male infertility and indicate CTA candidates for cancer
128 Loss of ADAM3 is strongly associated with male infertility and is observed in knockouts of male ge
129 , including a human mutation associated with male infertility and Mosaic Variegated Aneuploidy, disru
131 njection has revolutionized the treatment of male infertility and offers an alternative to vasectomy
132 ly, its use is expanding in the treatment of male infertility and patients with chronic testicular or
133 currently being explored in the treatment of male infertility and patients with chronic testicular pa
135 for the role of de novo mutations in severe male infertility and point to new candidate genes affect
136 of DMRT1 variants being a causal factor for male infertility and provide the distribution of likely
139 out of BRD7 (BRD7(-/-)) resulted in complete male infertility and spermatogenesis defects, including
140 se data demonstrate that BRD7 is involved in male infertility and spermatogenesis in mice, and BRD7 d
141 ignificant opportunity to identify causes of male infertility and targets for male contraceptives.
142 implications for common diseases, including male infertility and testicular cancer, due to abnormali
143 efect in men and is a predisposing factor of male infertility and testicular cancer, yet the etiology
144 ding raises the possibility for treatment of male infertility and testosterone deficiency through the
146 e leveraged to improve clinical screening of male infertility and ultimately reduce time to pregnancy
147 vitro fertilization techniques for treating male infertility and whole-animal cloning by nuclear tra
148 ception, 2111 (0.1%) had ART conception with male infertility, and 5603 (0.4%) had ART conception wit
150 d caused defective spermatid development and male infertility, and a phase separation-deficient FXR1(
151 y, and is also associated with pancreatitis, male infertility, and cachexia, features characteristic
152 t subregions of the epididymis, for treating male infertility, and for generating novel methods of ma
155 pertrophic cardiomyopathy to muscle wasting, male infertility, and mental retardation, yet recent rep
156 ammation, pancreatic exocrine insufficiency, male infertility, and might include several comorbiditie
160 hich structural variants have been linked to male infertility, and X-chromosome genes OPN1LW and OPN1
161 In mice and humans, growth insufficiency and male infertility are common disorders that are genetical
168 numerous genetic conditions associated with male infertility as well as emerging translational evide
170 reduction in H3.3 histone levels, leading to male infertility, as well as abnormal sperm and testes m
171 s may help to design new strategies to treat male infertility, as well as to identify potential targe
172 f the sNHE gene in mice resulted in absolute male infertility associated with a complete loss of sper
173 elopment as demonstrated by the incidence of male infertility associated with abnormal sperm ad shapi
176 of PHB in spermatocytes resulted in complete male infertility, associated with not only meiotic pachy
178 AMHCre and Rosa26CreERT2 lines) resulted in male infertility, atrophic testes with vacuolation, azoo
179 that genetic ablation ofCul4ain mice led to male infertility because of aberrant meiotic progression
180 soform, but not p53 or DeltaNp73, results in male infertility because of severe impairment of spermat
181 y linked to CF carriers (e.g., pancreatitis, male infertility, bronchiectasis), as well as some condi
182 ciated seminal microbiota abnormalities with male infertility but have yielded differing results owin
183 Meiotic arrest is a common cause of human male infertility, but the causes of this arrest are poor
184 olism have been widely implicated in causing male infertility, but there has been little progress in
185 rm injection revolutionized the treatment of male infertility by requiring a minimal number of sperm
190 ormal sense of smell, is a treatable form of male infertility caused by a congenital defect in the se
191 dy provided insights into a new mechanism of male infertility caused by the MKRN2 downregulation.
196 ame time, the TAM treatment reversed AF2ERKI male infertility compared with the vehicle-treated group
197 ociations between occupational exposures and male infertility could be identified in this study.
198 sp1 results in elevated perinatal lethality, male infertility, crosslinker hypersensitivity, and an F
199 Germ cell-specific deletion of Cul4bled to male infertility, despite normal testicular morphology a
201 m but show defects in growth after birth and male infertility due to a block in spermatogenesis.
202 However, the Taf7l disruption resulted in male infertility due to compromised testis development a
203 ermined TG repeat number in 98 patients with male infertility due to congenital absence of the vas de
204 ull-length transcript is sufficient to cause male infertility due to congenital bilateral absence of
205 been shown to cause cystic fibrosis (CF) and male infertility due to congenital bilateral absence of
207 have application for treating some cases of male infertility (e.g., secondary to gonadotoxic therapy
208 it ciliopathy-associated disorders including male infertility, early growth retardation, excessive we
209 pleiotropic, also resulting in sparse hair, male infertility, failure to thrive, and hydrocephaly, t
210 Poor sperm motility is a common cause of male infertility for which there are no empirical therap
211 upported by their homology with a Drosophila male infertility gene boule and sterility of Daz11 knock
213 cally, bs mice exhibit nuclear cataracts and male infertility; genetic analyses assigned the bs locus
214 er, to date, the association between OSA and male infertility has not been examined in a population-b
216 nisms, the mechanisms of temperature-induced male infertility have not been fully elucidated [5].
217 and is commonly characterized by sinusitis, male infertility, hydrocephalus, and situs inversus.
218 H2AX-/- mice, including growth retardation, male infertility, immune defects, chromosome instability
220 (close to 100% penetrance) and consequently male infertility in 3-4 and 5-6 weeks in mice and cynomo
221 c (LP/P) variants in 638 candidate genes for male infertility in 521 individuals presenting idiopathi
226 ntly related to RNA splicing factors, causes male infertility in mice by blocking the meiotic exit an
227 to defective sperm chromatin compaction and male infertility in mice, mirroring the observation of l
234 osure to elevated temperatures are linked to male infertility in several organisms, the mechanisms of
235 otential to lead to a therapy for idiopathic male infertility in the clinic, and could open the door
238 nt duct development is the dominant cause of male infertility in these mouse models, and this likely
242 have application for treating some cases of male infertility, including those caused by chemotherapy
243 fficiency (POI) recruited to the GEnetics of Male INfertility Initiative (GEMINI) or Estonian Androlo
251 suitability of rhesus macaques for studying male infertility is based on similarities in spermatogen
256 resents the most common cause of unexplained male infertility known thus far and that this sperm chan
257 e has been identified as causative for human male infertility, male mice deficient for members of the
259 mutations in EPPIN and an increased risk of male infertility, neither EPPIN nor any closely related
260 insights on some of the potential causes of male infertility, new underlining molecular mechanisms s
261 ith a severe CFTR mutation, 5T can result in male infertility, nonclassic cystic fibrosis, or a norma
264 oyed as an easily accessible system to study male infertility of humans and animals in terms of flage
265 Deletion of CETN1 or CETN2 in mice causes male infertility or dysosmia, respectively, without affe
266 The biggest improvement in the management of male infertility over the past 10 years has been the int
267 n specific stimulation, could participate in male infertility pathogenesis via inflammatory cytokine
268 one variant, observed in the MCM9 gene of a male infertility patient, compromised fertility or gamet
269 3-positive spermatozoa) were found in 51% of male infertility patients (n = 72), in 20% of men from c
278 ic and postmeiotic development, resulting in male infertility resembling oligoasthenoteratozoospermia
280 ngers of transmitting traits responsible for male infertility, sex and autosomal chromosome aberratio
282 te that the ERalpha AF-2 mutation results in male infertility, suggesting that the AF-1 is regulated
285 nd suggest that NCOA5 deficiency could cause male infertility through increased IL-6 expression in ep
288 intracytoplasmic sperm injection (ICSI) for male infertility was used and whether embryos were fresh
289 her RHOX cluster methylation associates with male infertility, we evaluated the methylation status of
290 hat mutations in CFTR are a leading cause of male infertility, we propose that defective ATP signalli
291 ility and randomly selected patients without male infertility were matched using a 1:4 propensity sco
292 resulting accumulation of GlcCer results in male infertility, whereas mutations in the GBA1 gene and
293 ave potential therapeutic value for treating male infertility, which afflicts >100 million men world-
294 ndrial morphology, synaptic dysfunction, and male infertility, which are features often observed in h
296 cture for organizing the complex genetics of male infertility, which may provide a rational basis for
297 y outcome was the association of the risk of male infertility with OSA exposure time interval (short
299 iral vectors can be used for gene therapy of male infertility without the risk of germ-line transmiss
300 AP91, an RS3 protein, is implicated in human male infertility, yet its molecular function remains poo