ライフサイエンスコーパス: malignant brain tumor

1 HOXA9 in glioblastoma (GBM), the most common malignant brain tumor.

2 n medulloblastoma, the most common childhood malignant brain tumor.

3 Glioblastoma (GBM) is the most common malignant brain tumor.

4 lioblastoma (GBM) is the most common primary malignant brain tumor.

5 the hypoxic region of glioblastoma, the most malignant brain tumor.

6 anner in glioblastoma (GBM), the most common malignant brain tumor.

7 Medulloblastoma is the most common pediatric malignant brain tumor.

8 Glioblastoma is the most common primary malignant brain tumor.

9 a is both the most common and lethal primary malignant brain tumor.

10 ations in the normal brain, and is common in malignant brain tumors.

11 ctive against a variety of tumors, including malignant brain tumors.

12 brain and that this pathway is subverted in malignant brain tumors.

13 get for new anti-invasive therapies to treat malignant brain tumors.

14 cells remaining after surgical debulking of malignant brain tumors.

15 of this approach in patients with recurrent malignant brain tumors.

16 option for patients with certain benign and malignant brain tumors.

17 ance in improving survival for patients with malignant brain tumors.

18 00 in treating both adults and children with malignant brain tumors.

19 m the suggested benefit from temozolomide in malignant brain tumors.

20 en infused intratumorally into patients with malignant brain tumors.

21 of IL-13R complex in 25 primary explants of malignant brain tumors.

22 in cellular immunotherapy trials for primary malignant brain tumors.

23 llular immunotherapy trials in human primary malignant brain tumors.

24 High-grade gliomas are the most aggressive malignant brain tumors.

25 erapy for some young children with recurrent malignant brain tumors.

26 atients with progressive growth of recurrent malignant brain tumors.

27 or experimental treatment of uniformly fatal malignant brain tumors.

28 cue (ABMR) for young patients with recurrent malignant brain tumors.

29 ft models, to determine its activity against malignant brain tumors.

30 ent antiproliferative activity against human malignant brain tumors.

31 tment-related changes (TRC) in patients with malignant brain tumors.

32 tem, accounting for approximately 80% of all malignant brain tumors.

33 e TBI was associated with risk of developing malignant brain tumors.

34 n extracellular matrix (ECM) are involved in malignant brain tumors.

35 ty in recurrent GBM, with potential in other malignant brain tumors.

36 f implementation in personalized medicine of malignant brain tumors.

37 enefit after standard of care has failed for malignant brain tumors.

38 e of high-grade glioma and other progressive malignant brain tumors.

39 or heterogeneity and geographic evolution of malignant brain tumors.

40 Glioblastomas are highly malignant brain tumors.

41 ne therapy approaches to treat patients with malignant brain tumors.

42 appaB signaling in combination therapies for malignant brain tumors.

43 all central nervous system tumors and 80% of malignant brain tumors.

44 ative thrombosis in patients with benign and malignant brain tumors.

45 rove the treatment outcomes of patients with malignant brain tumors.

46 lymerases, resulting in 'ultra-hypermutated' malignant brain tumors.

47 as well as diseases, including most notably malignant brain tumors.

48 receiving radiotherapy for the treatment of malignant brain tumors.

49 y contribute to the etiology of these highly malignant brain tumors.

50 that can improve management of patients with malignant brain tumors.

51 ession of the anti-bacterial gene deleted in malignant brain tumor 1 (DMBT1) is mediated by p38 and S

52 Lethal 3 malignant brain tumor 1 (L3MBTL1), a homolog of the Dros

53 Further, we find that lethal 3 malignant brain tumor 1 (L3MBTL1), a reader protein with

54 like, Ap15a-like, and ApNp35) and Deleted in Malignant Brain Tumor 1-like proteins.

55 ation and identification revealed deleted in malignant brain tumors 1 (DMBT1) (also known by the alia

56 The deleted in malignant brain tumors 1 (DMBT1) gene on 10q25-26 is a c

57 ernatively spliced product of the deleted in malignant brain tumors 1 (DMBT1) gene.

58 y agglutinin [SAG, encoded by the deleted in malignant brain tumors 1 (DMBT1) gene] is an innate immu

59 sephosphate isomerase (TPI1), and deleted in malignant brain tumors 1 protein (DMBT1).

60 Dmbt1 (deleted in malignant brain tumors 1) was identified as a candidate

61 e further show that expression of Deleted in Malignant Brain Tumors 1, the human homologue of the col

62 Glioblastoma is a prevalent malignant brain tumor and despite clinical intervention,

63 astoma multiforme is the most common primary malignant brain tumor and despite treatment with surgery

64 Glioblastoma (GBM) is the most malignant brain tumor and is highly resistant to intensi

65 ultiforme is the most common type of primary malignant brain tumor and may arise from a cell with neu

66 GB is the most common and aggressive primary malignant brain tumor and the current standard-of-care t

67 de gliomas (LGG) are the most common primary malignant brain tumors and are resistant to current ther

68 el therapeutic strategy for the treatment of malignant brain tumors and confirm the antitumor activit

69 B opening for drug delivery in patients with malignant brain tumors and effectively facilitate BBB cl

70 treatment related morbidity in infants with malignant brain tumors and in older children with standa

71 a multiforme (GBM) is one of the most common malignant brain tumors and its average survival time is

72 cell surface receptors are overexpressed in malignant brain tumors and reportedly involved in tumor

73 the rationale for targeting angiogenesis in malignant brain tumors and summarizes the results of rec

74 Glioblastoma is the most common primary malignant brain tumor, and is refractory to surgical res

75 deadly cancer, is the most lethal and common malignant brain tumor, and the leading cause of death in

76 Gliomas account for 77% of primary malignant brain tumors, and the prognosis has hardly cha

77 From a structural point of view, malignant brain tumors are classically characterized by

78 Approximately 49% of malignant brain tumors are glioblastomas, and 30% are di

79 ndividuals, and approximately 49% of primary malignant brain tumors are glioblastomas.

80 Malignant brain tumors are highly lethal and aggressive.

81 s of glioma, the most common type of primary malignant brain tumor, are poorly understood.

82 Glioblastomas (GBMs), the most common and malignant brain tumors, are highly resistant to current

83 or in 20 patients with pathologically proven malignant brain tumors (astrocytoma, n = 17; oligodendro

84 The primary outcome was development of malignant brain tumor based on International Classificat

85 iving acute lymphoblastic leukemia (ALL) and malignant brain tumors (BTs) have a higher incidence of

86 Glioblastoma is the most common primary malignant brain tumor, but despite multimodal treatment

87 stoma (GBM) is the most common type of adult malignant brain tumor, but its molecular mechanisms are

88 ma multiforme, the most common adult primary malignant brain tumor, but not in grade II to III glioma

89 ese studies offer a new concept for treating malignant brain tumors by improving the accumulation of

90 A significant proportion of children with malignant brain tumors can avoid radiotherapy and prolon

91 Potent immune responses against malignant brain tumors can be elicited by paracrine intr

92 ted the routine clinical care of challenging malignant brain tumor cases at a U.S. institution.

93 el in which the spatio-temporal expansion of malignant brain tumor cells is guided by environmental h

94 TM-601 binds to malignant brain tumor cells with high affinity and does

95 Glioblastoma (GBM) is a highly malignant brain tumor characterized by a heterogeneous p

96 Glioblastoma is a primary malignant brain tumor characterized by highly infiltrati

97 Glioblastoma (GBM) is the most malignant brain tumor characterized by intrinsic or acqu

98 Medulloblastoma (MB) is a pediatric malignant brain tumor composed of four different subgrou

99 Malignant brain tumors consist of a number of distinct s

100 Malignant brain tumors consist of malignancies originate

101 Traditional therapies for malignant brain tumors consist of surgical resection and

102 (GBM) is the most common and lethal primary malignant brain tumor, containing GBM stem cells (GSCs)

103 Nervous System Lymphomas (PCNSLs) are rare, malignant brain tumors derived from lymphocytes B.

104 Diffuse malignant brain tumors develop during early embryogenesi

105 Medulloblastoma is a malignant brain tumor diagnosed in children.

106 The protein deleted in malignant brain tumors (DMBT1) and the trefoil factor (T

107 ike family of proteins, often accompanied by malignant brain tumor domain (MBT) and sterile alpha mot

108 SFMBT1 belongs to the malignant brain tumor domain-containing chromatin reader

109 ide screen, we identified Scm-like with four malignant brain tumor domains 1 (SFMBT1) as a candidate

110 We present a protocol for using the triple malignant brain tumor domains of L3MBTL1 (3xMBT), which

111 BT1 (Scm [Sex comb on midleg] with four MBT [malignant brain tumor] domains 1) is a poorly characteri

112 The dismal prognosis of malignant brain tumors drives the development of new tre

113 resected tumors of 26 patients with advanced malignant brain tumors enrolled during December 2020 to

114 In archival malignant brain tumors expression levels of ALK and PTN

115 omplexes, polycomb repressive complexes, and malignant brain tumor family proteins, that collectively

116 pressor protein, the product of the lethal(3)malignant brain tumor gene.

117 endent intercellular signaling of the highly malignant brain tumor glioblastoma multiforme (GBM).

118 bitors for many tumors, including the highly malignant brain tumor glioblastoma.

119 ealed a number of miRNAs dysregulated in the malignant brain tumor glioblastoma.

120 romising therapeutic strategy for the highly malignant brain tumor, glioblastoma (GBM).

121 reat cancer, however, its efficacy in highly malignant brain-tumors, glioblastomas (GBM), is limited.

122 CL12 and its cognate receptor CXCR4 regulate malignant brain tumor growth and are potential chemother

123 lymphoblastic leukemia, hepatoblastoma, and malignant brain tumors had the highest risk of early dea

124 stoma (GBM), the most common type of primary malignant brain tumors harboring a subpopulation of stem

125 Glioblastoma, the most common primary malignant brain tumor, harbors a small population of tum

126 the activation of developmental programs in malignant brain tumors has emerged as a driver for growt

127 Glioblastoma, the predominant adult malignant brain tumor, has been computationally classifi

128 glioblastoma (GBM), the most common primary malignant brain tumor, have been defined, the intricate

129 re TBI group had a higher risk of developing malignant brain tumors (hazard ratio [HR], 1.67 [95% CI,

130 f medulloblastoma, the most common childhood malignant brain tumor: However, many long-term survivors

131 lioblastoma (GBM) is the most common primary malignant brain tumor in adults and carries a dismal pro

132 Glioblastoma is the most common malignant brain tumor in adults and carries a particular

133 ligodendrogliomas are the second most common malignant brain tumor in adults and exhibit characterist

134 Glioblastoma is the most common primary malignant brain tumor in adults and is associated with p

135 Glioblastoma is the most prevalent primary malignant brain tumor in adults and is characterized by

136 lioblastoma (GBM) is the most common primary malignant brain tumor in adults with a poor prognosis de

137 glioblastoma (GBM), the most common primary malignant brain tumor in adults, remains a significant u

138 own in glioblastoma, the most common primary malignant brain tumor in adults.

139 (GBM) is the most common and lethal primary malignant brain tumor in adults.

140 ioblastoma multiforme (GBM), the most common malignant brain tumor in adults.

141 lioblastoma (GBM) is the most common primary malignant brain tumor in adults.

142 Glioblastoma is the most lethal primary malignant brain tumor in adults.

143 astoma is the most common and lethal primary malignant brain tumor in adults.

144 o medulloblastoma formation, the most common malignant brain tumor in childhood.

145 igh-grade glioma (pHGG) is the most frequent malignant brain tumor in children and can be subclassifi

146 Medulloblastoma is the most common malignant brain tumor in children, and despite improveme

147 Medulloblastoma (MB) is the most prevalent malignant brain tumor in children, exhibiting clinical a

148 Medulloblastoma, the most common malignant brain tumor in children, is a biologically het

149 Medulloblastoma, the most common primary malignant brain tumor in children, is a radiosensitive a

150 eatment for medulloblastoma, the most common malignant brain tumor in children, remains limited to su

151 a subset of medulloblastoma, the most common malignant brain tumor in children, was found to contain

152 Medulloblastoma (MB) is the most common malignant brain tumor in children, where one-third of pa

153 Medulloblastoma is the most common malignant brain tumor in children.

154 tly linked to medulloblastoma (MB), a common malignant brain tumor in children.

155 that collectively represent the most common malignant brain tumor in children.

156 ve rise to medulloblastomas, the most common malignant brain tumor in children.

157 leading to medulloblastoma, the most common malignant brain tumor in children.

158 ormation in medulloblastoma, the most common malignant brain tumor in children.

159 l models of medulloblastoma, the most common malignant brain tumor in children.

160 combination therapy to treat the most common malignant brain tumor in children.

161 lts in medulloblastoma (MB), the most common malignant brain tumor in children.

162 origin for medulloblastoma, the most common malignant brain tumor in children.

163 on promotes medulloblastoma, the most common malignant brain tumor in children.

164 nating in the cerebellum, is the most common malignant brain tumor in children.

165 ciated with medulloblastoma, the most common malignant brain tumor in children.

166 Medulloblastoma (MB) is the most common malignant brain tumor in children.

167 Medulloblastoma is the most common malignant brain tumor in children.Chromosome arm 17p13.3

168 Glioblastoma is the most malignant brain tumor in humans and an average survival

169 Astrocytoma is the most common malignant brain tumor in humans.

170 Glioblastoma is the most common malignant brain tumor in humans.

171 poor prognosis, are the most common primary malignant brain tumors in adults.

172 e the most prevalent and devastating primary malignant brain tumors in adults.

173 Medulloblastoma, one of the most malignant brain tumors in children, is thought to arise

174 Medulloblastoma is among the most common malignant brain tumors in children.

175 omprise medulloblastoma, are the most common malignant brain tumors in children.

176 ma-derived myc (N-myc) is a leading cause of malignant brain tumors in children.

177 otherapy resulted in a high response rate of malignant brain tumors in infants.

178 Symptoms of malignant brain tumors include headache (50%), seizures

179 Other malignant brain tumors include primary central nervous s

180 system and the efficacy of gene therapy for malignant brain tumors include: 1) the design of more ef

181 dality of therapy for all commonly occurring malignant brain tumors, including medulloblastoma and gl

182 The annual incidence of primary malignant brain tumors is approximately 7 per 100 000 in

183 The incidence of primary malignant brain tumors is approximately 7 per 100 000 in

184 Evaluation of treatment effects in malignant brain tumors is challenging because of the lac

185 Medulloblastoma, the most common pediatric malignant brain tumor, is an example of a disease that h

186 Glioblastoma, the most common and aggressive malignant brain tumor, is propagated by stem-like cancer

187 MB, the most common pediatric malignant brain tumor, is treated with surgical resectio

188 blastoma multiforme, the most common form of malignant brain tumor,is resistant to all forms of thera

189 gene delivery in gene therapy strategies for malignant brain tumors, it is important to determine the

190 ogue of Drosophila tumor suppressor lethal(3)malignant brain tumor (l(3)mbt), binds histones in a met

191 Here, we identified Lethal(3)malignant brain tumor-like protein 1 (L3MBTL1) as a key

192 Lethal malignant brain tumors (lmbt) result from the loss of th

193 his mechanism persists in medulloblastoma, a malignant brain tumor markedly sensitive to radiation an

194 Malignant brain tumor (MBT) domain of PHF20L1 binds to m

195 ded abrogating binding of the Polycomb group malignant brain tumor (MBT) protein L3MBTL1 to lysine me

196 tial recognition of p53K382me1 by the triple malignant brain tumor (MBT) repeats of the chromatin com

197 Human L3MBTL1, which contains three malignant brain tumor (MBT) repeats, binds monomethylate

198 61, which encodes a protein composed of four malignant brain tumor (MBT) repeats.

199 We demonstrate that the malignant-brain-tumor (MBT) protein L3MBTL1 is in a comp

200 Glioblastoma is the most common primary malignant brain tumor of adults and one of the most leth

201 Glioblastoma is the most common malignant brain tumor of adults and one of the most leth

202 Medulloblastoma, the most common malignant brain tumor of childhood, is believed to deriv

203 uggest that medulloblastoma, the most common malignant brain tumor of childhood, is comprised of four

204 Medulloblastoma (MB) is the most common malignant brain tumor of childhood.

205 Medulloblastoma is a common malignant brain tumor of childhood.

206 Medulloblastoma is the most common malignant brain tumor of childhood.

207 ulloblastomas (PNET/MB), are the most common malignant brain tumor of childhood.

208 Medulloblastoma (MB) is the most common malignant brain tumor of children.

209 Medulloblastomas are the most common malignant brain tumors of childhood, and despite recent

210 Medulloblastoma is one of the most common malignant brain tumors of children, and 30% of medullobl

211 e blood-brain barrier (BBB) in patients with malignant brain tumors or metastases.

212 roliferation of abnormal microvasculature in malignant brain tumor patients, we have undertaken a cel

213 Caregivers of patients with primary malignant brain tumors (PMBT) experience significant psy

214 Malignant brain tumors pose diagnostic and therapeutic p

215 Malignant brain tumor prevalence was 0.6% in the moderat

216 the human homolog of the Drosophila lethal(3)malignant brain tumor protein, is a member of the polyco

217 ranscriptional repressor protein, lethal (3) malignant brain tumor protein, L(3)MBT, and the histone

218 Malignant brain tumors rank among the most challenging t

219 s without systemic toxicity in patients with malignant brain tumors refractory to conventional therap

220 In spite of intensive studies, malignant brain tumors remain to be a medical challenge.

221 apies, the clinical outcome of patients with malignant brain tumors remains extremely poor.

222 with Glioblastoma Multiforme (GM), a highly malignant brain tumor, remains poor despite concerted ef

223 It contains two MBT (malignant brain tumor) repeats; the MBT is a protein mod

224 Gliomas, the most common malignant brain tumors, represent the main focus of the

225 AAV-miRzip-21 and AAV-miR-7 in mice bearing malignant brain tumors resulted in significantly decreas

226 Mutations in any of three genes [l(3)malignant brain tumor, shackleton, and out of sync] affe

227 TB) is a major obstacle for drug delivery to malignant brain tumors such as glioblastoma (GBM).

228 egion, and rearrangements or inactivation in malignant brain tumors, suggest that LGI1 is a candidate

229 Medulloblastoma is a malignant brain tumor that arises in the cerebellum in c

230 Medulloblastoma (MB) is a malignant brain tumor that arises in the cerebellum of c

231 Medulloblastoma (MB) is a highly malignant brain tumor that occurs primarily in children.

232 Medulloblastoma (MB) is a malignant brain tumor that often arises in the cerebellu

233 Gliomas are highly malignant brain tumors that are highly invasive and resi

234 Glioblastomas are malignant brain tumors that are very difficult to cure,

235 Medulloblastomas are malignant brain tumors that arise by transformation of n

236 Medulloblastomas are malignant brain tumors that arise in the cerebellum in c

237 Medulloblastomas are malignant brain tumors that arise in the cerebellum in c

238 Diffuse gliomas are malignant brain tumors that include lower-grade gliomas

239 ermal tumors (PNETs) are a family of primary malignant brain tumors that include medulloblastomas.

240 A relatively novel combination treatment for malignant brain tumors that includes focused ultrasound

241 Glioblastomas are highly vascular malignant brain tumors that often overexpress vascular e

242 ight of clinical trials of oncolytic HSV for malignant brain tumors, these findings suggest that anti

243 Given the propensity for malignant brain tumors to infiltrate the surrounding nor

244 owever, the immune escape mechanisms used by malignant brain tumors to subvert this innate type of im

245 microenvironment might affect the ability of malignant brain tumors to traverse between brain and vas

246 lationships in newly diagnosed patients with malignant brain tumors treated with direct injections of

247 al antibody (MAb) in patients with recurrent malignant brain tumors, treated by direct injections of

248 New approaches to treating patients with malignant brain tumors use advanced magnetic resonance a

249 an effective agent used in the treatment of malignant brain tumors, was examined in an animal tumor

250 CXCL12 is a stroma-derived growth factor for malignant brain tumors, we tested the hypothesis that CX

251 (median age, 30 months) with newly diagnosed malignant brain tumors were enrolled onto this trial.

252 98 children younger than 3 years of age with malignant brain tumors were treated with prolonged posto

253 lastoma, one of the most prevalent childhood malignant brain tumors, were investigated to identify pr

254 cer drug discovery projects, but not yet for malignant brain tumors where type-II inhibition of cycli

255 erential regulation of cell proliferation in malignant brain tumors, which will have a broader impact

256 n younger than 6 years of age with recurrent malignant brain tumors who had not previously been expos

257 Glioblastoma multiforme (GBM) is a malignant brain tumor with a poor prognosis resulting fr

258 lioblastomas (GBMs), the most common primary malignant brain tumor with an unfavorable prognosis.

259 Glioblastoma (GBM) is a malignant brain tumor with diffuse infiltration.

260 toma multiforme (GBM) is a highly aggressive malignant brain tumor with fatal outcome.

261 Glioblastoma is the most common malignant brain tumor with less than 15 months median su

262 lioblastoma (GBM) is a highly aggressive and malignant brain tumor with limited therapeutic options a

263 Glioblastoma (GBM) is the most common malignant brain tumor with poor prognosis under the curr

264 Glioblastoma (GBM) is the most prevalent malignant brain tumor with poor prognosis.

265 ma is the most common and aggressive primary malignant brain tumor with poor prognosis.

266 glioma/GBM) is the most common primary adult malignant brain tumor with poor prognosis.

267 Glioblastomas (GBMs) are malignant brain tumors with a median survival of less th

268 s intracranial growth in xenograft models of malignant brain tumors with comparable efficacy to AMD 3

269 Treatment of malignant brain tumors with conventional approaches is l

270 igh-grade glioma (HGG) is a group of primary malignant brain tumors with dismal prognosis.

271 e investigated regional therapy of recurrent malignant brain tumors with transferrin-CRM107, a conjug

272 lastoma (GBM) is the most aggressive primary malignant brain tumor, with a median survival of approxi

273 ain tumor, accounting for nearly half of all malignant brain tumors, with a median survival rate of o

274 alignant gliomas are the most common primary malignant brain tumors, with an annual incidence of 5.26