ライフサイエンスコーパス: mannan-binding lectin

1 nd has ligand specificity similar to that of mannan-binding lectin.

2 ly reported for the lectin homologs SP-D and mannan-binding lectin.

3 consistently shown glomerular deposition of mannan-binding lectin (1 of 6 pattern-recognition molecu

4 way and absence of the LP complement protein mannan-binding lectin abrogates elastase-induced AAA.

5 Human beta-defensin 3 and mannan-binding lectin also blocked viral fusion by creat

6 Dendrimers are not sensed by C1q and mannan-binding lectin, and hence do not trigger compleme

7 ctin complement pathway via interaction with mannan binding lectin-associated serine proteases.

8 Mannan-binding lectin-associated serine protease 2 (MASP

9 n to enzymatically active FD is catalyzed by mannan-binding lectin-associated serine protease 3 (MASP

10 Here, we show that mannan-binding lectin-associated serine protease-1 (MASP

11 n pathway deficiency, a mouse strain lacking mannan-binding lectin-associated serine protease-2 (MASP

12 mediated by direct cleavage of native C3 by mannan-binding lectin-associated serine protease-2 bound

13 Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can a

14 C2 bypass route is dependent on LP-specific mannan-binding lectin-associated serine protease-2.

15 We found that the complex bound to mannan-binding lectin-associated serine proteases (MASPs

16 lecules leading to the activation of zymogen mannan-binding lectin-associated serine proteases (MASPs

17 H-ficolin is found in plasma associated with mannan-binding lectin-associated serine proteases (MASPs

18 ternative pathway and mannan-binding lectin, mannan-binding lectin-associated serine proteases 1 and

19 In serum, CL-L1 was found in complexes with mannan-binding lectin-associated serine proteases, sugge

20 anism, which is conserved in C1r and also in mannan-binding lectin-associated serine proteases, the s

21 Mannan-binding lectin-associated serine proteinase (MASP

22 Mannan-binding lectin-associated serine proteinase 2 (MA

23 eir binding by recognition molecules such as mannan-binding lectin, C-reactive protein and the mannos

24 in pathway (LP) showed that both ficolin and mannan-binding lectin can activate the LP through natura

25 ution of blistering had a similar pattern in mannan-binding lectin-deficient and control mice and was

26 ys in this model, we injected C1q-deficient, mannan-binding lectin-deficient, and factor B-deficient

27 he lectin activation pathway upon binding of mannan-binding lectin, ficolins, or collectin kidney 1 (

28 Mannan-binding lectin, known to share some functions wit

29 and factor H in the alternative pathway and mannan-binding lectin, mannan-binding lectin-associated

30 substrate complex consisting of glycan-bound mannan-binding lectin, MASP-2, and C4 is discussed.

31 Measurement of mannan binding lectin (MBL) antigenic level and activity

32 Mannan binding lectin (MBL) is an innate immune mediator

33 nt, the pattern recognition molecules (PRMs) mannan-binding lectin (MBL) and ficolins complexed with

34 C1q and mannan-binding lectin (MBL) are not only recognition com

35 In teleost fish, the immune functions of mannan-binding lectin (MBL) associated protein (MAP) and

36 Mannan-binding lectin (MBL) constitutes an important par

37 Mannan-binding lectin (MBL) is a C1q-like molecule opson

38 Mannan-binding lectin (MBL) is a component of the innate

39 Mannan-binding lectin (MBL) is an important protein of t

40 b, CR1 was reported to interact with C1q and mannan-binding lectin (MBL) likely through its C-termina

41 It is activated upon binding of mannan-binding lectin (MBL) or ficolins (H-, L-, and M-f

42 ght to occur via recognition of pathogens by mannan-binding lectin (MBL) or ficolins in complex with

43 activation by Neisseria gonorrhoeae via the mannan-binding lectin (MBL) pathway in normal human seru

44 Levels of the serum opsonin mannan-binding lectin (MBL) were directly correlated wit

45 Mannan-binding lectin (MBL), a member of the collectin f

46 iple helices are critical in the function of mannan-binding lectin (MBL), an oligomeric recognition m

47 t the soluble pattern recognition molecules, mannan-binding lectin (MBL), L-ficolin, and M-ficolin, w

48 The pattern recognition molecule, mannan-binding lectin (MBL), plays an important role in

49 ction of an endogenous complement inhibitor, mannan-binding lectin (MBL)-associated protein (MAp)44,

50 Mannan-binding lectin (MBL)-associated serine proteases,

51 oligomannose glycans on serum IgD and IgE to mannan-binding lectin (MBL).

52 ified as mannan-specific, and named mosquito mannan-binding lectin (MBL).

53 found that the C7 rs6876739 CC genotypes and mannan-binding lectin (MBL2) gene polymorphisms of liver

54 Also, the mannan-binding lectin (MBL2), an innate immune lectin th

55 w the complement system is activated via the mannan-binding-lectin pathway.

56 omplement cascade but not the alternative or mannan-binding lectin pathways.

57 MASP1 encodes mannan-binding lectin serine protease 1.

58 ession of eight proteins-Granulin precursor, Mannan-binding-lectin-serine-peptidase-2, Endoplasmatic-

59 All three proteins inhibited binding of mannan-binding lectin to the polysaccharide mannan, prev

60 lement components revealed that C1q, but not mannan-binding lectin, was required for complement activ

61 etic deficiency in early complement, IgM, or mannan-binding lectin were characterized in a mesenteric

62 to ischemic Ag providing a binding site for mannan-binding lectin which subsequently leads to activa

63 to the same areas that stain positively for mannan-binding lectin, which suggests that the complemen

64 complexes that are formed upon engagement of mannan-binding lectin with its serine proteases.