ライフサイエンスコーパス: mannose 6-phosphate receptor

1 protein had altered binding affinity for the mannose 6-phosphate receptor.

2 the bifunctional, IGF-II cation-independent mannose 6-phosphate receptor.

3 ecause of uptake of enzyme from blood by the mannose 6-phosphate receptor.

4 patocytes, suggesting diffuse uptake via the mannose 6-phosphate receptor.

5 lin-like growth factor II/cation-independent mannose 6-phosphate receptor.

6 that Asn-175 mutants could interact with the mannose 6-phosphate receptor.

7 proton pump, but lacking cation-independent mannose 6-phosphate receptor.

8 asmic granules by a mechanism other than the mannose 6-phosphate receptor.

9 signals of the transferrin receptor or large mannose 6-phosphate receptor.

10 state localization of the cation-independent mannose 6-phosphate receptor.

11 rane proteins such as the cation-independent mannose 6-phosphate receptor.

12 ith high affinity for the cation-independent mannose 6-phosphate receptor.

13 e cytoplasmic tail of the cation-independent mannose 6-phosphate receptor.

14 r and failed to bind to the cation-dependent mannose 6-phosphate receptor.

15 nclusion that the interacting protein is the mannose-6 phosphate receptor.

16 2 chimera containing a cytosolic domain of a mannose-6-phosphate receptor.

17 ng the basis for lysosomal transport via the mannose-6-phosphate receptor.

18 lular distribution of the cation-independent mannose-6-phosphate receptor.

19 r to those containing the cation-independent mannose-6-phosphate receptor.

20 ous to the recycling signal of the mammalian mannose-6-phosphate receptor.

21 s competent for lysosomal uptake through the mannose-6-phosphate receptor.

22 argeted to the lysosome independently of the mannose-6-phosphate receptor.

23 glycosaminoglycans and a cation-independent mannose-6-phosphate receptor.

24 upstream of the steady-state distribution of mannose 6-phosphate receptors.

25 tifs present in the cytoplasmic tails of the mannose 6-phosphate receptors.

26 the cation-independent and cation-dependent mannose 6-phosphate receptors.

27 the cation-independent and cation-dependent mannose 6-phosphate receptors.

28 lization with transferrin receptors and some mannose 6-phosphate receptors.

29 e, resulting in the peripheral dispersion of mannose 6-phosphate receptors.

30 -phosphate, indicating lysosomal sorting via mannose 6-phosphate receptors.

31 osis of lysosomal enzymes via the mannose or mannose 6-phosphate receptors.

32 human GGA3 complexed with signals from both mannose-6-phosphate receptors.

33 trast to wild-type ASA, which is taken up by mannose-6-phosphate receptors, all chimeric proteins wer

34 he acid hydrolases to the cation-independent mannose 6-phosphate receptor allows sufficient sorting t

35 Cation-independent mannose-6-phosphate receptor, also called insulin-like g

36 de transferrin, fluid phase markers, and the mannose-6-phosphate receptor, although in the perinuclea

37 ndependent mechanisms, but are devoid of the mannose 6-phosphate receptor and cathepsin L.

38 ecreased affinity for the cation-independent mannose 6-phosphate receptor and failed to bind to the c

39 itutive (transferrin receptor) and regulated mannose 6-phosphate receptor and GLUT4 trafficking to th

40 d by two distinct MPRs: the cation-dependent mannose 6-phosphate receptor and the insulin-like growth

41 r, and low amounts of the cation-independent mannose 6-phosphate receptor and the lysosome-associated

42 e receptors including the cation-independent mannose 6-phosphate receptor and the mannose receptor.

43 chinery that mediates the trafficking of the mannose 6-phosphate receptors and associated cargo from

44 nd lysosomal acid phosphatases but also with mannose 6-phosphate receptors and cathepsin L.

45 ow visualization of endocytosis of mod2B via mannose 6-phosphate receptors and delivery of mod2B to l

46 s of GCC185 triggers enhanced degradation of mannose 6-phosphate receptors and enhanced secretion of

47 s Rab9 GTPase and the cytoplasmic domains of mannose 6-phosphate receptors and is required for their

48 the cation-independent and cation-dependent mannose 6-phosphate receptors and is required for their

49 rectly leads to impaired recycling of 46-kDa mannose 6-phosphate receptors and partial mistargeting o

50 p40 cofractionates with endosomes containing mannose 6-phosphate receptors and the Rab9 GTPase.

51 oteins such as furin, the cation-independent mannose-6-phosphate receptor and in viral proteins such

52 of cargoes, including the cation-independent mannose-6-phosphate receptor and semaphorin 4C, by the m

53 nto cells via sortilin or cation-independent mannose 6-phosphate receptor, and facilitated the acidif

54 tor 2 receptor (IGF2R), a cation-independent mannose-6-phosphate receptor, and increases expression o

55 l G-proteins, including Ras, up-regulate the mannose-6-phosphate receptor, and induce apoptosis.

56 d lysosomal marker proteins, including Rab7, mannose-6-phosphate receptor, and LAMP-1.

57 the cytoplasmic tail of the cation-dependent mannose 6-phosphate receptor are palmitoylated via thioe

58 gnition by the insulin-like growth factor II/mannose 6-phosphate receptor are predicted by sequence a

59 Cation-independent mannose 6-phosphate receptors are enriched in the Rab9 d

60 also stimulates the initial rate with which mannose 6-phosphate receptors are transported from late

61 the cation-independent and cation-dependent mannose-6-phosphate receptors, are recognized by the GGA

62 ach other and to the 46 kDa cation-dependent mannose 6-phosphate receptor, assemble into a compact st

63 s, the GGAs appear to mediate sorting of the mannose 6-phosphate receptors at the trans-Golgi network

64 targeted to the lysosome through binding to mannose 6-phosphate receptors because their glycans are

65 5 min, then contained the cation-independent mannose 6-phosphate receptor between 2.5 and 7.5 min, an

66 t monitors the transport of cation-dependent mannose 6-phosphate receptors between endosomes and the

67 47 kDa (TIP47; also known as perilipin-3 and mannose-6-phosphate receptor-binding protein 1), a membe

68 uolar protein sorting 35 homolog), and M6PR (mannose 6-phosphate receptor) blocked PrP(C) internaliza

69 ile ectopic expression of cation-independent mannose-6 phosphate receptor blocks apoptosis induced by

70 e studies show TGN localization of furin and mannose-6-phosphate receptor, but not TGN46, is strictly

71 Mannose 6-phosphate receptors carry newly synthesized ly

72 lysosome is mediated by the cation-dependent mannose 6-phosphate receptor (CD-MPR) and the insulin-li

73 cid cytoplasmic tail of the cation-dependent mannose 6-phosphate receptor (CD-MPR) contains a signal(

74 luble truncated form of the cation-dependent mannose 6-phosphate receptor (CD-MPR) encoding only the

75 The cation-dependent mannose 6-phosphate receptor (CD-MPR) is a key component

76 The 46 kDa cation-dependent mannose 6-phosphate receptor (CD-MPR) plays a key role i

77 increased expression of the cation-dependent mannose 6-phosphate receptor (CD-MPR), which is partiall

78 The cation-dependent and cation-independent mannose 6-phosphate receptors (CD- and CI-MPRs) bind the

79 g proteins, including the cation-independent mannose 6 phosphate receptor (CI-M6PR), which coordinate

80 ss receptors, such as the cation-independent mannose 6-phosphate receptor (CI-M6PR), to direct extrac

81 on the trafficking of the cation-independent mannose 6-phosphate receptor (CI-M6PR).

82 ly recognize cargoes like cation-independent mannose 6-phosphate receptor (CI-MPR) and Insulin-like g

83 The 300 kDa cation-independent mannose 6-phosphate receptor (CI-MPR) and the 46 kDa cat

84 The 300-kDa cation-independent mannose 6-phosphate receptor (CI-MPR) and the 46-kDa cat

85 ii) Cells transduced with cation-independent mannose 6-phosphate receptor (CI-MPR) block apoptosis in

86 mplex, which recycles the cation-independent mannose 6-phosphate receptor (CI-MPR) from endosomes to

87 ramatic redistribution of cation-independent mannose 6-phosphate receptor (CI-MPR) from its normal pe

88 h the distribution of the cation-independent mannose 6-phosphate receptor (CI-MPR) has been well stud

89 The 300 kDa cation-independent mannose 6-phosphate receptor (CI-MPR) is a multifunction

90 The cation-independent mannose 6-phosphate receptor (CI-MPR) is clinically sign

91 The cation-independent mannose 6-phosphate receptor (CI-MPR) mediates sorting o

92 The 300 kDa cation-independent mannose 6-phosphate receptor (CI-MPR) mediates the intra

93 The 300-kDa cation-independent mannose 6-phosphate receptor (CI-MPR) plays a critical r

94 ctivation is regulated by cation-independent mannose 6-phosphate receptor (CI-MPR), a protein that fa

95 h affinity ligand for the cation-independent mannose 6-phosphate receptor (CI-MPR), and we analyzed t

96 The 300-kDa cation-independent mannose 6-phosphate receptor (CI-MPR), which contains mu

97 be because of inefficient cation-independent mannose 6-phosphate receptor (CI-MPR)-mediated endocytos

98 rk (TGN) transport of the cation-independent mannose 6-phosphate receptor (CI-MPR).

99 e cytoplasmic tail of the cation-independent mannose 6-phosphate receptor (CI-MPR).

100 ity of the cation-independent and -dependent mannose 6-phosphate receptors (CI-MPR and CD-MPR) for hi

101 early endosomes, and the cation-independent mannose-6-phosphate receptor (CI-M6PR), a component of l

102 n ATPase (V-ATPase), the calcium-independent mannose-6-phosphate receptor (CI-M6PR), or cathepsin D.

103 tein NPC2, a cargo of the cation-independent mannose-6-phosphate receptor (CI-M6PR).

104 g a target protein to the cation-independent mannose-6-phosphate receptor (CI-M6PR).

105 that are agonists of the cation-independent mannose-6-phosphate receptor (CI-M6PR).

106 ograde trafficking of the cation-independent mannose-6-phosphate receptor (CI-MPR) and sortilin.

107 d to this pathway are the Cation-Independent Mannose-6-phosphate receptor (CI-MPR) and the ATP7B copp

108 The cation-independent mannose-6-phosphate receptor (CI-MPR) follows a highly r

109 as been attributed to low cation-independent mannose-6-phosphate receptor (CI-MPR) in skeletal muscle

110 attributed to inefficient cation-independent mannose-6-phosphate receptor (CI-MPR) mediated uptake.

111 to-Golgi retrieval of the cation-independent mannose-6-phosphate receptor (CI-MPR), a receptor for ly

112 clenbuterol treatment on cation-independent mannose-6-phosphate receptor (CI-MPR)-mediated uptake an

113 tion between SNX5 and the cation-independent mannose-6-phosphate receptor (CI-MPR).

114 ome-to-Golgi retrieval of cation-independent mannose-6-phosphate receptors (CI-MPR) in the soma is di

115 erouted AP-1, endocytosed cation-independent mannose 6-phosphate receptor (CIMPR) accumulated in a pe

116 25 ArfGAPs for effects on cation-independent mannose 6-phosphate receptor (CIMPR) localization.

117 anges the distribution of cation-independent mannose 6-phosphate receptor (CIMPR) without affecting t

118 t for the localization of cation independent mannose-6-phosphate receptor (CIMPR) at Golgi.

119 ferrin receptor (TfR) and Cation-Independent Mannose-6-Phosphate Receptor (CIMPR), and the conserved

120 eficient form of the bovine cation-dependent mannose 6-phosphate receptor complexed to pentamannosyl

121 of the interaction of recombinant TIP47 with mannose 6-phosphate receptor cytoplasmic domains.

122 und to be taken up by uncorrected cells in a mannose-6-phosphate receptor-dependent manner.

123 The enzyme is delivered by a mannose-6-phosphate receptor-dependent mechanism to the

124 e sulfotransferase and monitors transport of mannose 6-phosphate receptors engineered to contain a co

125 receptors, including the cation-independent mannose 6-phosphate receptor for lysosomal enzymes.

126 ates the retrieval of the cation-independent mannose 6-phosphate receptor from endosomes to the trans

127 f drug had no effect on the transport of the mannose 6-phosphate receptor from late endosomes to the

128 the retrograde sorting of Cation-independent Mannose 6-Phosphate Receptor from late endosomes.

129 1 causes a mislocalization of both furin and mannose 6-phosphate receptor from the trans-Golgi networ

130 TIP47 functions in the delivery of mannose 6-phosphate receptors from endosomes to the tran

131 rt processes, their role in the transport of mannose 6-phosphate receptors from endosomes to the tran

132 o transport assay that measures transport of mannose 6-phosphate receptors from endosomes to the tran

133 Rab9 GTPase is required for the transport of mannose 6-phosphate receptors from endosomes to the tran

134 We study the transport of mannose 6-phosphate receptors from late endosomes to the

135 ab9A and its effectors regulate recycling of mannose 6-phosphate receptors from late endosomes to the

136 ab9A and its effectors regulate transport of mannose 6-phosphate receptors from late endosomes to the

137 ated cholesterol on Rab9-dependent export of mannose 6-phosphate receptors from this compartment.

138 mes to the TGN, but not for the retrieval of mannose-6-phosphate receptor from late endosomes.

139 This protein was known to transport mannose-6-phosphate receptors from endosome to trans-Gol

140 tracellular region of the cation-independent mannose-6-phosphate receptor has gained an IGF-II-bindin

141 st time the three-dimensional structure of a mannose 6-phosphate receptor homology (MRH) domain prese

142 n, the N-terminal part of Yos9 including the mannose 6-phosphate receptor homology domain mediates th

143 Inactivation of the mannose 6-phosphate receptor homology domain of OS9 had

144 trates that in the majority of instances the mannose 6-phosphate receptor homology domain of the gamm

145 We postulate that the mannose 6-phosphate receptor homology domain of the gamm

146 is an ER-resident glycoprotein containing a mannose-6-phosphate receptor homology domain, which is a

147 lin-like growth factor II/cation-independent mannose 6-phosphate receptor (IGF-II/CI-MPR).

148 g sites of the insulin-like growth factor-II/mannose 6-phosphate receptor (IGF-II/MPR) have been loca

149 The insulin-like growth factor-II/mannose 6-phosphate receptor (IGF-II/MPR) is a type I gl

150 on-independent insulin-like growth factor-II/mannose 6-phosphate receptor (IGF-IIR) with IGFs and man

151 The insulin-like growth factor II/mannose 6-phosphate receptor (IGF2R) carries out multipl

152 Ligands of the IGF-II/mannose 6-phosphate receptor (IGF2R) include IGF-II and

153 The insulin-like growth factor II/mannose 6-phosphate receptor (IGF2R) interacts with lyso

154 g the insulin-like growth factor II (IGF-II)/mannose 6-phosphate receptor (IGF2R), is frequently inac

155 lysosomal membranes, the accumulation of the mannose 6-phosphate receptor in and the recruitment of t

156 However, mutant PPT enzymes did not bind to mannose 6-phosphate receptors in a blotting assay.

157 altered the steady-state distribution of the mannose-6-phosphate receptor in the cell.

158 argo, sortilin, SorLA and cation-independent mannose 6-phosphate receptor, in rodent primary neurons

159 , endocytic markers delivered to vacuoles by mannose 6-phosphate receptor-independent mechanisms, but

160 These results implicate MMR-independent and mannose 6-phosphate receptor-independent pathways in phL

161 o numerous ligands and plays a major role in mannose 6-phosphate receptor-independent transport of ly

162 Two such proteins, mannose 6-phosphate receptor-interacting protein TIP47 a

163 ired incorporation of the cation-independent mannose 6-phosphate receptor into clathrin-coated vesicl

164 two proteins may cooperate in packaging the mannose 6-phosphate receptors into clathrin-coated vesic

165 etwork to lysosomes and the incorporation of mannose-6-phosphate receptors into CCVs.

166 These vesicles contain the mannose 6-phosphate receptor involved in targeting prote

167 The insulin-like growth factor II/mannose 6-phosphate receptor is a multifunctional recept

168 receptor tyrosine kinase, whereas the IGF-2/ mannose 6-phosphate receptor is a single transmembrane d

169 binds more tightly to the cation-independent mannose 6-phosphate receptor (K(D) = 1 microm) than to t

170 (D) = 1 microm) than to the cation-dependent mannose 6-phosphate receptor (K(D) = 3 microm).

171 Antibodies directed to the mannose-6-phosphate receptor labeled vacuole membranes.

172 rs of transport vesicles (cation-independent mannose 6-phosphate receptor), late endosomes (Ras-assoc

173 istribution of markers of the TGN (TGN38 and mannose 6-phosphate receptors) led us to propose that GG

174 osomal tubules and redistributes a conserved mannose 6-phosphate receptor-like protein from endosomes

175 athepsin D) and late endosomal markers (anti-mannose-6-phosphate receptor), lysosomal markers (CD-63)

176 sorting nexin 1 (SNX1), as well as decreased mannose 6 phosphate receptor (M6PR), suggesting the impa

177 Protein levels of another mannose 6-phosphate receptor (M6PR)-dependent enzyme, B-

178 lls, both the late autophagy pathway and the mannose-6-phosphate receptor (M6PR) pathway are interrup

179 -like growth factor-II receptor (IGF-IIR), a mannose-6-phosphate receptor (M6PR) that binds to cathep

180 alization of specific cargo proteins (furin, mannose-6-phosphate receptor (M6PR), and M6PR lacking a

181 II (IGF2) enhances memory in rodents via the mannose-6-phosphate receptor (M6PR), but the underlying

182 Uptake of recombinant enzyme is via the mannose-6-phosphate receptor (M6PR).

183 domains of the insulin-like growth factor II/mannose 6-phosphate receptor (Man-6-P/IGF2R), located in

184 but not with Rab7 or the cation-independent mannose 6-phosphate receptor, markers for late endosomal

185 Here, we demonstrate that mannose 6-phosphate receptor-mediated cellular uptake an

186 6-phosphate, suggesting cation-independent, mannose 6-phosphate receptor-mediated endocytosis from t

187 enzyme is delivered to neonatal brain after mannose 6-phosphate receptor-mediated transcytosis.

188 tion, the induction of tolerance may require mannose 6-phosphate receptor-mediated uptake because alp

189 by repeated high doses of enzyme depends on mannose 6-phosphate receptor-mediated uptake or whether

190 subtypes of MPS knockout cell lines through mannose-6-phosphate receptor-mediated endocytosis in vit

191 ces, and can be taken up by distal cells via mannose-6-phosphate receptor-mediated endocytosis.

192 secreted into the circulation for subsequent mannose-6-phosphate receptor-mediated tissue uptake.

193 g pathways for insulin-like growth factor-II/mannose 6-phosphate receptor (MPR) and transferrin recep

194 brane protein LIMP-2 has been a paradigm for mannose 6-phosphate receptor (MPR) independent lysosomal

195 fEndosome-to-Golgi retrieval of the mannose 6-phosphate receptor (MPR) is required for lysos

196 OCRL1 and IPIP27A localize to mannose 6-phosphate receptor (MPR)-containing traffickin

197 in maintaining Golgi structure and tethering mannose 6-phosphate receptor (MPR)-containing transport

198 R) on macrophages, ERT targets primarily the mannose 6-phosphate receptor (MPR).

199 y transient but dramatic upregulation of the mannose-6-phosphate receptor (MPR) on the tumor cell sur

200 endosomal membranes as that followed by the mannose-6-phosphate receptor (MPR), and consistent with

201 mbrane cargo includes the cation-independent mannose-6-phosphate receptor (MPR).

202 or subpopulation of mature lysosomes lacking mannose-6-phosphate receptors (MPR) and smaller populati

203 n cell lines deficient in cation-independent mannose 6-phosphate receptors (MPRci).

204 the cation-dependent and cation-independent mannose 6-phosphate receptors (MPRs) and is required for

205 n-dependent (CD) and cation-independent (CI) mannose 6-phosphate receptors (MPRs) and is required for

206 olgi network (TGN) is mediated by binding to mannose 6-phosphate receptors (MPRs) and subsequent capt

207 in a late endosome microdomain together with mannose 6-phosphate receptors (MPRs) and the tail-intera

208 Mannose 6-phosphate receptors (MPRs) are transported fro

209 Mannose 6-phosphate receptors (MPRs) are transported fro

210 n-independent (CI) and cation-dependent (CD) mannose 6-phosphate receptors (MPRs) bind specifically t

211 Mannose 6-phosphate receptors (MPRs) deliver lysosomal h

212 Mannose 6-phosphate receptors (MPRs) deliver newly synth

213 Mannose 6-phosphate receptors (MPRs) deliver soluble aci

214 ns (GGAs) are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) in the Golgi and ha

215 Mannose 6-phosphate receptors (MPRs) participate in the

216 Mannose 6-phosphate receptors (MPRs) play an important r

217 olases to lysosomes relies on transmembrane, mannose 6-phosphate receptors (MPRs) that cycle between

218 is required for Rab9-dependent recycling of mannose 6-phosphate receptors (MPRs) to the Golgi and fo

219 Mannose 6-phosphate receptors (MPRs) transport newly syn

220 oated vesicles that form on the TGN, are the mannose 6-phosphate receptors (MPRs).

221 y known to exhibit low and high affinity for mannose-6-phosphate receptors (MPRs), respectively.

222 reduced in hydrolytic enzymes transported by mannose-6-phosphate receptors (MPRs).

223 was taken up by a combination of mannose and mannose 6-phosphate receptors (MR and M6PR, respectively

224 y into the endosomal/lysosomal system by the mannose 6-phosphate receptor, N- and C-terminal proseque

225 This effect was mediated via upregulation of mannose-6-phosphate receptors on the surface of tumor ce

226 on the trafficking of the cation-independent mannose 6-phosphate receptor or the GLUT1 glucose transp

227 nked dimer, the majority is directed via the mannose-6-phosphate receptor pathway to endocytic compar

228 lysosomal enzymes reach the lysosome via the mannose-6-phosphate receptor pathway.

229 h-muscle cell interaction may be mediated by mannose 6-phosphate receptors present on monocytes.

230 d loss of TC II-R but not cation-independent mannose 6-phosphate receptor protein at the basolateral

231 ficking of an endocytosed cation-independent mannose 6-phosphate receptor reporter from early endosom

232 We found that the cation-independent mannose-6-phosphate receptor serves as typhoid toxin sor

233 le form of the insulin-like growth factor II/mannose 6-phosphate receptor (sIGF-II/MPR) is present in

234 skin fibroblasts and/or chondrocytes via the mannose-6-phosphate receptor system, leading to metaboli

235 All three GGAs (1, 2, and 3) bind to the mannose 6-phosphate receptor tail via their VHS domains,

236 t therapy specifically designed for enhanced mannose-6-phosphate-receptor targeting and enzyme uptake

237 CD36, nitric oxide synthase type 2, and the mannose-6 phosphate receptor) that are known to be palmi

238 fficking to the lysosome, presumably via the mannose 6-phosphate receptor, the 110-kDa precursor unde

239 lations of the insulin-like growth factor-II/mannose 6-phosphate receptor, the transferrin receptor,

240 six knockdowns cause the cation-independent mannose 6-phosphate receptor to become trapped in cluste

241 y sequence alignment to the cation-dependent mannose 6-phosphate receptor to reside within domains 3

242 for the retrieval of the cation-independent mannose 6-phosphate receptor to the TGN.

243 ck in Rab6-dependent retrograde transport of mannose 6-phosphate receptors to the Golgi.

244 This blocks retrieval of mannose 6-phosphate receptors to the TGN and impairs cat

245 ts and control Rab9-dependent trafficking of mannose-6-phosphate receptor to lysosomes.

246 We used two independent assays of mannose 6-phosphate receptor trafficking to determine th

247 pe C cell membranes, which in turn, disrupts mannose 6-phosphate receptor trafficking.

248 nt that is independent of cation-independent mannose 6-phosphate receptor trafficking.

249 of endo-lysosomes, as well as impairment of mannose-6-phosphate-receptor trafficking.

250 membranes along with clathrin, giantin, the mannose 6-phosphate receptor, transferrin, and the early

251 th Rab9 in terms of its ability to stimulate mannose 6-phosphate receptor transport.

252 GA3 but not GGA2 bind the cation-independent mannose 6-phosphate receptor very poorly because of auto

253 ome-associated membrane protein-2 (LAMP2)(+)/mannose 6-phosphate receptor(-) vesicles that can be dis

254 eficient hepatocytes, whereas that of 46-kDa mannose 6-phosphate receptor was decreased to 30% of con

255 Expression of the cation-dependent 46 kDa mannose 6-phosphate receptor was elevated in pyramidal n

256 The cation-independent mannose 6-phosphate receptor was not colocalized with ei

257 somal-prelysosomal marker cation-independent mannose 6-phosphate receptor was not detectable in the v

258 The steady-state level of 300-kDa mannose 6-phosphate receptor was slightly lower in LAMP-

259 ylation of desialylated cell surface 300-kDa mannose 6-phosphate receptors, we found that receptor en

260 Rab, synaptojanin, and the cation-dependent mannose 6-phosphate receptor were used to explore wild-t

261 n-Pick type C membranes, as cation-dependent mannose 6-phosphate receptors were missorted to the lyso

262 tered distribution of the cation-independent mannose 6-phosphate receptor, which normally sorts acid

263 the surface expression or internalization of mannose 6-phosphate receptors, which are required for VZ

264 or (IGF2R), also known as cation-independent mannose-6-phosphate receptor, which is involved in traff

265 delivery was independent of high-mannose and mannose-6-phosphate receptors, which are exploited for d

266 1 reaches the vacuole even in the absence of mannose-6-phosphate receptors, which are responsible for

267 ilure of fission caused defective sorting of mannose 6-phosphate receptor, with consequently disrupte

268 o a column of immobilized cation-independent mannose 6-phosphate receptor, with the strongest binding

269 at interact with the cytoplasmic tail of the mannose 6-phosphate receptor, yet its sequence is highly

270 r to that of avidin and the cation-dependent mannose 6-phosphate receptor, yet only domain 11 binds I