ライフサイエンスコーパス: margin

1 -treat-exposed population (4% noninferiority margin).

2 was outside the prespecified noninferiority margin.

3 surface to detect PC tissue at the resection margin.

4 ine and >500 m depth, beyond the continental margin.

5 fference, peritumoral enhancement, and tumor margin.

6 ing microbial enemy release beyond the range margin.

7 ift and highly extended (<15 km) continental margin.

8 V(FB) value (-0.02 V vs Fc/Fc(+)) by a wide margin.

9 d, therefore, avoid setting a noninferiority margin.

10 oonal alluvial plains into an extremely arid margin.

11 in (0 mm margin) and R0 as at least a 0.1 mm margin.

12 closure, and 5-6 mm was the mostly preferred margin.

13 tforms for assessing a drug's cardiac safety margin.

14 d, less than 50 km from the Alpine ice sheet margin.

15 cious, with an absolute 0.75% noninferiority margin.

16 300 km south of the contemporaneous Eurasian margin.

17 rimary tumor, >=4 CRLM, and positive hepatic margin.

18 f consensus guidelines defining a "positive" margin.

19 of the 95% CI was within the noninferiority margin.

20 ptosis was not observed in the human fissure margins.

21 ly invoke more oxidized fluids at convergent margins.

22 romotion of cell division at primordial leaf margins.

23 ng contemporaneous re-assessment of positive margins.

24 ture and reduced gene flow towards the range margins.

25 ce of tumor in the stain was considered free margins.

26 for accurate detection of positive surgical margins.

27 methods for the intraoperative assessment of margins.

28 eoplasms, which have little granular data on margins.

29 osphere in the forearc regions of convergent margins.

30 arbon seeps are ubiquitous along continental margins.

31 ological type), and presence/absence of free margins.

32 in stabilising population dynamics at range margins.

33 ting property distributions within and among margins.

34 s can be important for setting upslope range margins.

35 overlying intra-retinal fluid and indistinct margins.

36 oproterozoic ocean focused along continental margins.

37 assessment that visualizes <1% of the tissue margins.

38 R1 was defined as a microscopically involved margin (0 mm margin) and R0 as at least a 0.1 mm margin.

39 icating better health status; noninferiority margin, 0.05 points).

40 int was powered for equivalence (equivalence margin 10% with significance level 0.05) and consisted o

41 monovalent OPV2 in infants (non-inferiority margin 10%).

42 erion for noninferiority for this end point (margin, -10 percentage points).

43 both of which were below the noninferiority margin (2 stools).

44 different between patients with R0 versus R1 margins (2- and 5-year local recurrence free survivals o

45 included vitreous attachment at the coloboma margin (23.33%), vitreous condensation (6.67%), and hill

46 pendent chronology of the history of the GIS margin(3,4).

47 or noninferiority for the primary end point (margin, 6 percentage points).

48 th tested for noninferiority (noninferiority margin, 7.5 percentage points) and superiority.

49 uentially for noninferiority (noninferiority margin, 7.5 percentage points) and superiority.

50 cluding 51 patients with an initial negative margin (82.4% with < 2 mm), and 157 with an initial posi

51 s are a noncalcified solid nodule with sharp margins; a round, oval, or polygonal shape; distanced 15

52 and upper eyelid meiboscores (P = .012), lid margin abnormality scores (P = .0059), and meibum qualit

53 At temperate tidewater margins, abundant subglacial meltwater forms morainal ba

54 als, while demonstrating considerable safety margins against platelet reduction in a nonhuman primate

55 nificantly more apical shift of the gingival margin (almost two-fold).

56 we found no differences in hydraulic safety margin among species, suggesting that all trees may be e

57 However, our study showed a narrower safety margin and a limited increased efficiency at the posteri

58 the distance between the temporal optic disc margin and foveal center, and the vertical diameter not

59 , we determined the relationship between the margin and original IPMN using driver gene mutations ide

60 f QME for detecting tumor within 1 mm of the margin and the potential for this technique to improve o

61 deep-sea fish assemblage on the West African margin and, if so, identify potential cues for the behav

62 In Group A, 13.2% had involved margins and 13.2% underwent a second surgical interventi

63 that can improve the visualization of tumor margins and adjuvant therapies to ablate remaining tumor

64 eye and 2 others had scarring of the eyelid margins and blepharitis.

65 Weeds are often abundant in field margins and ditches surrounding agricultural landscapes.

66 all unsprayed treatments with non-crop plant margins and in corresponding sprayed treatments (with bo

67 Associations between margins and overall survival and local recurrence free s

68 ups were not significant (p=0.7 for involved margins and p=0.5 for reintervention).

69 al and flexible distal stipes, serrate frond margins and presence of sporophylls) and L. spicata (rig

70 ss variable APC datasets and improved safety margins and proarrhythmic risk assessments.

71 ar infiltration beyond the macroscopic tumor margins and to quantify neo-angiogenesis.

72 d as a microscopically involved margin (0 mm margin) and R0 as at least a 0.1 mm margin.

73 midway of the xiphoid process and the costal margin, and 1 cm above the umbilicus, respectively.

74 tures, such as calcification, poorly defined margin, and a markedly hypoechoic solid nodule; and beni

75 neural invasion, T-stage, N-stage, resection margin, and adjuvant chemotherapy were correlated with O

76 r reconstruction, 62 (85%) had negative (R0) margins, and 24 (33%) had a complete or major pathologic

77 36; P = 0.024); and iris hooks at the rhexis margin (aOR, 6.99; P < 0.001).

78 ical techniques-suturing the vestibular flap margin apically to the base of the recipient bed versus

79 18.6% of patients, tumor-positive resection margins are detected on histopathology.

80 Continental margins are disproportionally important for global prima

81 ed, and imaged to determine whether surgical margins are free of tumor cells-a costly and time- and l

82 rgins; however, recent data suggest narrower margins are sufficient, and for benign PT, a negative ma

83 Complete removal and negative margins are the goal of any surgical resection of primar

84 cal zipping" forces along the outer cortical margin as well as tension in the white matter core, toge

85 scent imaging using 6qcNIR allows 100% tumor margin assessment by generating en face images that corr

86 for the early detection and for the surgical-margin assessment of epithelial cancers of the upper int

87 mplementation of an accurate, intraoperative margin assessment tool may reduce this re-excision rate.

88 tissue sampling during intraoperative tumor-margin assessment, while offering an affordable tool to

89 Margin assessments by imaging and by the surgeon were re

90 ses negative following the first Mohs stage, margin assessments correlated with histopathology in 39

91 imaging, and was further validated in cancer margin assessments using human medulloblastoma cancers.

92 cy of periodontal probe through the gingival margin at midfacial level.

93 est Pleistocene interglacials, the ice sheet margin at the Wilkes Basin retreated to near the precipi

94 nts require repeat surgery due to inadequate margins at the initial operation.

95 ve assessment can be used to ensure negative margins at the time of surgery.

96 ation imaging (OPI) for the detection for KC margins before Mohs surgery with promising results.

97 t BioConceptVec consistently has, by a large margin, better performance than existing concept embeddi

98 requires precisely locating and defining the margins between lesions and normal tissue.

99 However, this is made difficult by irregular margin borders.

100 different between patients with R0 versus R1 margins but wider resection margins do not confer a surv

101 methods consistently and with a significant margin, but neither unsupervised nor semi-supervised rep

102 on the pattern of lava flooding of tesserae margins by adjacent plains volcanism.

103 or malignancy involvement of dissected tumor margins by introducing two crucial classification parame

104 es were analysed (composition, echogenicity, margin, calcification status, the presence of halo and o

105 Cells lining the OF margin can maintain RPE fate ectopically and fail to tra

106 A 5% noninferiority margin compared with enoxaparin was chosen.

107 ation is limited by the large noninferiority margin compared with the low observed event rate, as wel

108 The noninferiority margin corresponds to a 12% absolute difference between

109 Negative circumferential resection margins (CRM) are the cornerstone for the curative treat

110 % (n = 74) of those with an initial positive margin did not undergo a second operation, among whom on

111 % [95% CI, 5.2%-13.2%]; P < .001; net income margin: difference, 3.6% [95% CI, 0.011%-7.2%]; P = .05)

112 search and development expense (gross profit margin: difference, 30.5% [95% CI, 20.9%-40.1%]; P < .00

113 0.5% [95% CI, 20.9%-40.1%]; P < .001; EBITDA margin: difference, 9.2% [95% CI, 5.2%-13.2%]; P < .001;

114 ith R0 versus R1 margins but wider resection margins do not confer a survival benefit [57 months (95%

115 contrast agents can be used to define tumour margins during surgery in real time, the selectivity of

116 tatistically significant differential profit margin favoring pharmaceutical companies was evidence of

117 e do not recommend re-excision of a negative margin for benign PT, regardless of margin width, as a p

118 The non-inferiority margin for overall response was defined using a 60% rete

119 The non-inferiority margin for overall survival was set as a hazard ratio (H

120 ference that did not meet the noninferiority margin for placebo.

121 nclude requiring only the 1.3 noninferiority margin for regulatory approval, conducting trials for lo

122 r-free days at day 28, with a noninferiority margin for the difference in ventilator-free days at day

123 and inappropriate shocks; the noninferiority margin for the upper boundary of the 95% confidence inte

124 of the recipient bed versus leaving the flap margin free and unsutured.

125 nsutured when compared with leaving the flap margin free.

126 gher than, those in flu Without SAFE1, grana margins (GMs) of chloroplast thylakoids (Thys) are speci

127 Margins >0.5 mm were not predictive of local recurrence

128 Current guidelines recommend >= 1 cm margins; however, recent data suggest narrower margins a

129 complete resection of adrenal metastasis (R1 margins; HR: 1.62, P = 0.034; R2 margins; HR: 5.45, P =

130 astasis (R1 margins; HR: 1.62, P = 0.034; R2 margins; HR: 5.45, P = 0.002) were associated with short

131 The 2 plaques provided a safety margin in 43% versus 40% eyes, provided no safety margin

132 base of the graft; whereas, the mucosal flap margin in the control group was left free.

133 ifies ray flower identity at the flower head margin in the model plant Gerbera hybrida We discovered

134 bduction initiation occurred along a passive margin in the northwest Indian Ocean.

135 nables detection of tumor-positive resection margins in 9/9 subjects and four additional otherwise mi

136 Inadequate margins in breast-conserving surgery (BCS) are associate

137 Clearance of surgical margins in cervical cancer prevents the need for adjuvan

138 cts causing insufficient alignment of the OF margins in Nf2 mutants and failure to fuse properly, res

139 The nanosuspension enabled sufficient margins in preclinical toleration studies to nominate 12

140 n the first reading and for echogenicity and margins in the second reading, which had moderate concor

141 could aid surgeons in assessing oral cancer margins in vivo.

142 MARGINS included patients eligible for breast-conserving

143 nce imaging (CLI) for assessment of surgical margins intraoperatively during radical prostatectomy.

144 city to provide accurate assessment of tumor margin involvement in breast-conserving surgery.

145 tage, surgical approach, time of surgery and margin involvement mGPS (p < 0.05) was associated with C

146 any high-risk pathologic features (nodal or margin involvement or LVI), adjuvant chemotherapy follow

147 motherapy (DM 83.0%, LR 16.9%) regardless of margin-involvement (DM 80.1%, LR 19.4%).

148 ttern also remained consistent regardless of margin-involvement (DM 94.1%, LR 5.9%).

149 erforming FSTA surgery when the mucosal flap margin is left free and unsutured when compared with lea

150 A microscopically clear resection margin is most important in predicting overall survival.

151 A 1-2 mm margin is often used to define R0 but this is based on p

152 of the northern South China Sea continental margin is strikingly similar to the broad continental ri

153 amics in a small number of cells at the leaf margin is tightly associated with the control of differe

154 gin width, as a progressively wider surgical margin is unlikely to reduce LR.

155 h (PPD), bleeding on probing (BoP), gingival margin level, dentin hypersensitivity, and percent of po

156 ng scenarios, with the greatest contribution margin loses ($1,650,000 per surgeon-year) realized with

157 re sufficient, and for benign PT, a negative margin may not be necessary.

158 ence generated (also found along the Tethyan margin) may be considered as a smoking gun for this type

159 kup time (TBUT), corneal staining and eyelid margin measurements, meibum quality, meibomian gland exp

160 shaft cells of the Drosophila anterior wing margin mechanosensory bristles undergo PCP-directed apic

161 The R0 (circumferential resection margin negative) resection rate was 28%.

162 up until the age of 17 wk (at an equivalence margin of +/-3.0 g/d).

163 29 431 for Medicare Advantage (mean hospital margin of -$30 828+/-$39 757 for medicare fee for servic

164 dy drug, with a prespecified non-inferiority margin of -10%.

165 l was within the prespecified noninferiority margin of -9 percentage points.

166 Recession with a non-inferiority margin of 0.4 mm (p = 0.05).

167 o 0.246) were all within the non-inferiority margin of 0.5 mm.

168 A noninferiority margin of 1.08 in terms of hazard ratio was prespecified

169 rity analysis with the use of a prespecified margin of 1.25 on the relative scale.

170 s less than the prespecified non-inferiority margin of 1.62 (IRR 0.47 [95% CI 0.19-1.15]).

171 s less than the prespecified non-inferiority margin of 1.62.

172 Drug Administration snapshot approach and a margin of 10 percentage points to define the non-inferio

173 A non-inferiority margin of 10% was used.

174 C for the average radiologist by an absolute margin of 11.5%.

175 A noninferiority margin of 12% was used.

176 calculated to detect inferiority of RC8 by a margin of 12%.

177 -3.626 letters, exceeding the noninferiority margin of 3.5 letters.

178 letters, which is within the noninferiority margin of 4 letters.

179 both of which were below the noninferiority margin of 4 percentage points.

180 on-to-treat exposed), with a non-inferiority margin of 4%.

181 mpared with tirofiban using a noninferiority margin of 9%, superiority of both tirofiban and cangrelo

182 A non-inferiority margin of absolute differences of 20% was used.

183 points, with 10 points being a commonly used margin of clinical relevance.

184 nting a modern human presence on the western margin of Iberia ~5,000 years earlier than previously kn

185 , was assessed in a noninferiority analysis (margin of noninferiority, 7.5 percentage points).

186 hondria inheritance, (3) accumulation in the margin of nonrecombining regions of various factors, inc

187 ng eyes open/closed), (2) walking stability (Margin of Stability during normal/dual-task walking), (3

188 The non-inferiority margin of the 10% was not reached (difference=7.0%; 95%C

189 We studied this system near the range margin of the alligatorweed flea beetle to test whether

190 tive was to describe the OCT features at the margin of the coloboma.

191 ar tissue was identified along the posterior margin of the corneas and DSAEK buttons in all cases.

192 Eluting Seeds (iDES) for insertion into the margin of the GBM resection cavity to provide a sustaine

193 ow that Eocene extension across the northern margin of the South China Sea records the transition bet

194 city, for detecting tumor within 1 mm of the margins of BCS specimens.

195 rogeneously on relict quartz surfaces at the margins of coesite-bearing inclusions.

196 evice, for real-time diagnosis of suspicious margins of dissected tumors to declare more precise intr

197 The division boundary forms between the margins of expression of CdaI and CdaA, which exclude ea

198 atients, and colocalized with B cells at the margins of follicles.

199 multaneous OCT and QME were performed on the margins of intact, freshly excised specimens from 83 pat

200 ed homeobox3 (WOX3) homolog expressed at the margins of leaf primordia, and is required for mediolate

201 result of HSIL and detection of HSIL at the margins of LEEP sample.

202 taken at polypectomy sites or assessments of margins of resected polyps.

203 Given low profit margins of smallholder farmers (2 to 9%), the range of p

204 CN groups, bone formation was limited to the margins of the defects at 30 postoperative days, whereas

205 across the ablation zone of land terminating margins of the Greenland Ice Sheet over multi-annual tim

206 system critically controls ice motion at the margins of the Greenland Ice Sheet.

207 Due to positive margins on final permanent sections, the patient underwe

208 nic lithosphere is emplaced onto continental margins (ophiolites), and along the seafloor as faulting

209 ve control) while treatments with bare earth margin or sprayed with water (negative controls) had the

210 as, either on the buccal or lingual gingival margin, or circumferentially forming a "ring around the

211 tage 3 or 4, Gleason score of 7-10, positive margins, or preoperative PSA >=10 ng/mL) for biochemical

212 Boost dose (P < .001) and boost margin (P = .001) differed between groups.

213 oning (hazard ratio [HR], 2.81 for no safety margin; P = 0.041).

214 Crop margin plantings of Ageratum conyzoides, Tridax procumbe

215 ; new cementum (NC); new bone (NB); gingival margin position; total epithelium length; epithelium on

216 nal accessory nerves and because of a likely margin-positive (R1 or R2) result.

217 significantly correlated with recurrence in margin-positive patients.

218 Measured parameters included resection rate, margin positivity, pathologic response, and toxicity.

219 regression and non-inferiority analyses (25% margin, power 80%).

220 en had histopathologically positive surgical margins (PSMs), and 2 of 3 PSMs were accurately detected

221 ssessed by gastroscopy, histology (resection margin [R] positivity of polypectomy or biopsy), EUS, CT

222 erative eyelid height or postoperative upper margin reflex distance (MRD1) of less than 2 mm.

223 Margin reflex distance 1 (MRD1), MRD2, and levator funct

224 mpared between groups, with a noninferiority margin (relative difference) of 15%.

225 ole of species interactions in setting range margins remains poorly understood.

226 ized by an apical discrepancy of the mucosal margin respective to its ideal position with or without

227 fined as an apical migration of the gingival margin respective to the cementoenamel junction resultin

228 ), and 10 (4.8%) patients had R0, R1, and R2 margins, respectively.

229 Swept-source OCT of the coloboma margin revealed new features in addition to the previous

230 on the occurrence of submarine landslides at margin scale are lacking, leaving unanswered a link betw

231 Measurements on about 313 human breast tumor margins showed more than 90% accuracy and near 93% speci

232 triangular; polygonal; round; or irregular), margin (smooth or nonsmooth), and attachment to the cost

233 mber of ribs resected did not correlate with margin status (p = 0.36).

234 .39; 95% CI, 0.07 to 2.10; P = .27) or final margin status (positive v negative: OR = 0.96; 95% CI, 0

235 have presented mixed results on the role of margin status in risk of recurrence after surgical resec

236 We compared the tumor margin status on CLI to postoperative histopathology.

237 Stratification factors were Gleason score, margin status, planned radiotherapy schedule (52.5 Gy in

238 3.3%) and remained consistent independent of margin-status.

239 ic Guidance in Breast-Conserving Therapy, or MARGINS, study.

240 for iRLT and trophic differences along range margins, surveying the mammal community along the boreal

241 terbodies with abundant wetlands along their margins than those without wetlands.

242 ed delayed growth kinetics and more distinct margins than tumors derived from control TICs.

243 -resection treatment of remaining unresected margins, thanks to a molecular construct designed to rai

244 ecords from the northeastern Tibetan Plateau margin that are dated precisely from ~35.5 to 31 Ma by c

245 flexed down a previously rifted continental margin thereby contributing to subsidence of flanking se

246 the role of T cells, especially at the wound margin; these cells may support the destructive autoinfl

247 PFS) at week 48, using a 15% non-inferiority margin to compare the investigational groups against the

248 s within and beyond the species' local range margin to determine if the addition of social informatio

249 n in 43% versus 40% eyes, provided no safety margin to guard foveola in 17% versus 33%, and did not e

250 r-microdissection RNA-seq of leaf primordial margins to identify gene targets bound and modulated by

251 lled, open-label, non-inferiority trial (10% margin) to compared immunogenicity following administrat

252 eyelid position improvement using lower lid margin-to-pupillary reflex distance was the most common

253 ntle and forced eyelid closure, upper eyelid margin-to-reflex distance (MRD1), corneal staining, stat

254 OFC in which epithelial cells at the fissure margins undergo a transient epithelial-to-mesenchymal-li

255 PPR within 1 radius of the disc margin underwent 7.6 +/- 1.6 mum average temporal displa

256 Margins up to 0.5 mm offers a local recurrence benefit b

257 , p<0.001) and healthcare/social care costs (margin US$17 524, -24 763 to -10 284, p<0.001).

258 d detection of oral lesion heterogeneity and margins using optical coherence tomography.

259 ference product on the basis of prespecified margins, using a study population and efficacy end point

260 The noninferiority margin was 0.1 logarithm of the minimum angle of resolut

261 The noninferiority margin was 1.3 (upper boundary of a 95.6% confidence int

262 The prespecified noninferiority margin was 1.75 percentage points.

263 The non-inferiority margin was 10%.

264 The noninferiority margin was 3.5 letters.

265 The noninferiority margin was 4 letters.

266 The noninferiority margin was 8%.

267 The non-inferiority margin was a hazard ratio (HR) of 1.3.

268 The non-inferiority margin was a hazard ratio (HR) of 2.0.

269 The prespecified noninferiority margin was a relative risk (RR) of 0.90.

270 A R2 margin was defined as macroscopic residual disease.

271 Although positive margin was not significantly associated with recurrence

272 pattern toward apical shift of the gingival margin was noticed for the ADM-adjacent untreated sites

273 In the test group the mucosal flap margin was sutured apically to the periosteum at the bas

274 variable logistic regression with predictive margins was used to compare outcomes.

275 intraoperative complications, and resection margins, was performed.

276 on, in a subset of 32 patients with positive margins, we determined the relationship between the marg

277 int width, and location relative to the disc margin were also analyzed.

278 Enhancement and sharpness of the tumor margin were associated with expression of ribosomal prot

279 , p = 0.05), and CD3 + cells at the invasive margin were associated with improved disease-free surviv

280 with shape (odds ratio, 0.73; P = .005) and margin were significant (odds ratio, 0.80; P = .001).

281 ize and grade of the dysplastic focus at the margin were significantly correlated with recurrence in

282 Stem P50 and hydraulic safety margin were the most strongly related physiological trai

283 mm with LOS or triangular shapes and smooth margins were benign.

284 Surgical margins were positive in 42% (n = 231) and negative in 5

285 ellar effusion, and irregular cartilage-bone margin, were similar between hemiplegic and non-hemipleg

286 ion zone and proximal pull-through resection margin where ENS was present.

287 tiling pattern and relocated to the ChP-free margin where they breached the weakened epithelial barri

288 inland from the current position of the ice margin, which-assuming current ice volumes-would have co

289 grades) was not reduced with wider negative margin width (>= 2 mm v < 2 mm: odds ratio [OR] = 0.39;

290 For the entire cohort, a wider margin width was not associated with a reduced risk of L

291 negative margin for benign PT, regardless of margin width, as a progressively wider surgical margin i

292 f the oral tumour and the surgical resection margin with more than 95% sensitivity and specificity.

293 ween enhancements and sharpness of the tumor margin with the ribosome suggests that these MRI feature

294 were trained to effectively read fluorescent margins with a short guided instruction, highlighting cl

295 then surgery and radiotherapy boost based on margins with continued chemotherapy).

296 h to adaptive lymphocytes, which softens the margins with innate lymphocyte populations and allows in

297 led pathological features of the parenchymal margin) with recurrence after surgical resection.

298 th < 2 mm), and 157 with an initial positive margin, with residual disease only found in six (2.9%).

299 rovide histologic-quality images of surgical margins without physical sectioning.

300 have been documented in numerous continental margins worldwide, their geometry, controls and emplacem