ライフサイエンスコーパス: marijuana

1 from n = 568 (illicit opioids) to n = 4272 (marijuana).

2 drocannabinol (THC), the primary CB found in marijuana.

3 isting for patients using legal recreational marijuana.

4 l marijuana, and 4 states allow recreational marijuana.

5 failure for transplant who use legal medical marijuana.

6 US states and countries that legalize retail marijuana.

7 glaucoma patients in a state with legalized marijuana.

8 ta9-THC), the major psychoactive compound in marijuana.

9 , one of the main psychoactive components of marijuana.

10 ctive compound tetrahydrocannabinol (THC) in marijuana.

11 t medical justifications for legalization of marijuana.

12 mucosal microbiota with frequent smoking of marijuana.

13 viduals driving under the influence (DUI) of marijuana.

14 Cannabis sativa, or marijuana, a popular recreational drug, alters sensory p

15 ressed especially politicized health issues (marijuana, abortion, and firearm storage).

16 A may lead to novel treatment strategies for marijuana abuse.

17 Such laws could convey a message about marijuana acceptability that increases its use soon afte

18 nding treatment options, the legal status of marijuana, addressing the opioid epidemic, insurance cov

19 related to psychiatric vulnerability (e.g., marijuana, alcohol, and caffeine misuse, perceived stres

20 nt users of marijuana with 4.6 million using marijuana almost daily.

21 ervational data suggest associations between marijuana and a broad range of adverse cardiovascular ri

22 On the other hand, marijuana and alcohol might follow an additive effect tr

23 0.362 to -0.128; P < .001), and relevance of marijuana and glaucoma treatment costs (beta, 0.127; 95%

24 etween frequent recreational cannabis (FRC) (marijuana and hashish) use and periodontitis prevalence

25 Marijuana and hemp were crossed to evaluate competing mo

26 ed high-throughput screening and chemotyping marijuana and hemp, as well as other botanical products.

27 ers to determine the history of recommending marijuana and influencing factors for or against this re

28 oducts by children, the relationship between marijuana and opioid use, and whether there will be an i

29 Self-report data on marijuana and other drug use occasions were collected an

30 for education regarding the risk of smoking marijuana and prevention messages.

31 d to questionnaires including information on marijuana and recreational drug use during the past 3 mo

32 iated with smoking in the past month, use of marijuana and recreational drugs, prescription drug misu

33 ncurrent with changes in the legal status of marijuana and societal attitudes regarding its use.

34 ffects, and proposed mechanisms of action of marijuana and summarizes the available literature regard

35 y demonstrates striking similarities between marijuana and tobacco smoke in terms of their physical a

36 Marijuana and tobacco use were each independently associ

37 2015, almost half of US states allow medical marijuana, and 4 states allow recreational marijuana.

38 with other drugs (such as nicotine, alcohol, marijuana, and antidepressant) with infants with similar

39 heroin, ecstasy, methamphetamines, synthetic marijuana, and prescription drug abuse, including severa

40 late the effects of the active ingredient of marijuana, and they have gained enormous popularity over

41 rs (MAR), smoking-and-marijuana users (SAM), marijuana-and-drinking users (MAD), and users of all thr

42 Attitudes toward marijuana are changing, the prevalence of DSM-IV cannabi

43 Few glaucoma specialists have recommended marijuana as a treatment for glaucoma, and an even small

44 veral limitations associated with the use of marijuana as a treatment for glaucoma.

45 rijuana for glaucoma, but only 2.6% had used marijuana as a treatment for glaucoma.

46 inol (THC), the primary active ingredient in marijuana, as assessed with self-administration (SA), ha

47 ased acceptability among the public of using marijuana based on false perceptions of its therapeutic

48 medical and recreational use of cannabis, or marijuana, becomes more prevalent, law enforcement needs

49 to 0.444; P < .001), false beliefs regarding marijuana (beta, 0.323; 95% CI, 0.236 to 0.504; P < .001

50 subsequent perceived harmfulness and use of marijuana by adolescents.

51 ent of a specific phytochemical component of marijuana called cannabidiol (CBD), which possesses prom

52 Use of marijuana (Cannabis sativa) often begins in adolescence,

53 ical questions about the long-term impact of marijuana (Cannabis sativa) that are especially importan

54 HC) and cannabidiol (CBD) occur naturally in marijuana (Cannabis) and may be formulated, individually

55 is becoming increasingly potent, and smoking marijuana carries many of the same cardiovascular health

56 Annual RPC pediatric marijuana cases increased more than 5-fold from 2009 (9)

57 el.SIGNIFICANCE STATEMENTCannabis sativa, or marijuana, causes euphoria and exerts a wide range of me

58 veral approaches to synthesizing measures of marijuana, cocaine, heroin, ecstasy, methamphetamines, s

59 nce of tetrahydrocannabinolic acid (THCA) in marijuana compared with cannabidiolic acid (CBDA) in hem

60 esses a potential unifying mechanism whereby marijuana could exert rewarding and addictive/withdrawal

61 The main psychoactive compound in marijuana, Delta(9)-tetrahydrocannabinol (THC), and its

62 disorder (OR, 2.03 [95% CI, 1.03-3.99]), and marijuana dependence (OR, 2.88 [95% CI, 1.07-7.71]) comp

63 in cannabis, play major roles in tobacco and marijuana dependence as reinforcers of drug-seeking and

64 and THC that play major roles in tobacco and marijuana dependence: (1) maintenance of high rates of d

65 Analyses including both alcohol and marijuana did not support an independent role for mariju

66 A total of 203 of the 300 medical marijuana dispensaries called were successfully contacte

67 ceptions among glaucoma specialists, medical marijuana dispensaries, and glaucoma patients in a state

68 In contrast, many marijuana dispensary employees endorse its use.

69 First, medical marijuana dispensary employees were surveyed using a mys

70 pairments in offspring of mothers that abuse marijuana during pregnancy.

71 As legal access and public acceptance of marijuana escalate, physicians should be aware of these

72 in measured IQ may not be a direct result of marijuana exposure but rather attributable to familial f

73 's hospital, and Colorado's RPC received 163 marijuana exposure cases between January 1, 2009, and De

74 Marijuana exposure visits and RPC cases, marijuana sourc

75 iatric disorders, and deleterious effects of marijuana exposure.

76 ren's hospital visits and RPC case rates for marijuana exposures increased between the 2 years prior

77 The median age of RPC marijuana exposures was 2 years (IQR, 1.3-4.0), and 85 p

78 RPC cases from Colorado for single-substance marijuana exposures.

79 wine data set and mass spectra of different marijuana extracts were used.

80 S-DA and SVC to classify the mass spectra of marijuana extracts with an overall accuracy of 97%.

81 ersisted even when adolescents stopped using marijuana for a year.

82 Use of marijuana for chronic pain, neuropathic pain, and spasti

83 regarding patients' perceptions toward using marijuana for glaucoma and their intentions to use this

84 nificantly associated with intentions to use marijuana for glaucoma treatment after controlling for d

85 (58.9%) had heard about the possible use of marijuana for glaucoma, but only 2.6% had used marijuana

86 main outcome was patients' intentions to use marijuana for glaucoma.

87 associated with patients' intentions to use marijuana for glaucoma.

88 ce of treatment costs, and intentions to use marijuana for glaucoma.

89 As legalization of marijuana for medical and recreational use continues, th

90 lationship between US state laws that permit marijuana for medical purposes and adolescent marijuana

91 The effect of legalizing marijuana for recreational use on rates of adolescent ma

92 ts (7.6%) reported that they had recommended marijuana for the treatment of glaucoma, with the majori

93 orts the listing of patients who use medical marijuana for transplant after a period of abstinence.

94 Marijuana has drawn significant public attention and con

95 C), which is the main bioactive component in marijuana, has also been shown to possess potent anti-in

96 Cannabis sativa, commonly called cannabis or marijuana, has been used for its psychotropic and mind-a

97 Cannabis, or marijuana, has potential therapeutic and medicinal prope

98 Marijuana (hereafter "tetrahydrocannabinol [THC]") use h

99 The increasing use of medical marijuana highlights the importance of developing a bett

100 no roadside DUI test exists for determining marijuana impairment, thus the merit lies in detecting t

101 uana did not support an independent role for marijuana in alcohol effects on cerebellar gray matter t

102 vey to assess trends in self-reported use of marijuana in electronic cigarettes among US middle schoo

103 vascular diseases currently use or have used marijuana in its variety of forms, including inhalation

104 Observations: Marijuana in oncology may have potential for use as an a

105 all areas related to the therapeutic use of marijuana in oncology.

106 Colorado RPC cases for pediatric marijuana increased significantly and at a higher rate t

107 table to familial factors that underlie both marijuana initiation and low intellectual attainment.

108 gly relevant, including the effects of acute marijuana intoxication on driving abilities, unintention

109 nce were administered at ages 9-12 y, before marijuana involvement, and again at ages 17-20 y.

110 Marijuana is becoming increasingly potent, and smoking m

111 Marijuana is becoming legal in an increasing number of s

112 Marijuana is classified as a Schedule I substance, thus

113 Marijuana is distinguished from hemp by a nonfunctional

114 Marijuana is listed as a Schedule I substance under the

115 Marijuana is one of the most commonly used drugs in the

116 Although marijuana is the most commonly abused illicit drug, the

117 Marijuana is the most widely used illicit drug in the Un

118 The rapidly changing sociopolitical marijuana landscape provides a foundation for the therap

119 US adults, and 28 states have passed medical marijuana laws (MML).

120 Twenty-nine states have medical marijuana laws (MMLs) and of these, 8 have recreational

121 aws (MMLs) and of these, 8 have recreational marijuana laws (RMLs).

122 Medical marijuana laws appear to have contributed to increased p

123 tes and the District of Columbia had medical marijuana laws in place.

124 the increases in such risks, and the role of marijuana laws in these increases.

125 onsequences associated with changes in state marijuana laws should receive consideration by health ca

126 Given changes in U.S. marijuana laws, attitudes, and use patterns, individuals

127 e and the practical implications for medical marijuana laws.

128 ers is urgently needed because of increasing marijuana legalisation in multiple jurisdictions, the ef

129 ashington and Colorado prior to recreational marijuana legalization (2010-2012) with postlegalization

130 As marijuana legalization is increasing, research regarding

131 They are usually purchased as marijuana-like drugs, marketed as herbal blends and perc

132 Adolescents who regularly use marijuana may be at heightened risk of developing subcli

133 While medical marijuana may help some, cannabis-related health consequ

134 found at high levels in modern varieties of marijuana--may be detrimental to CB1 signaling, particul

135 plantation after a period of abstinence from marijuana (n=241, 68.3%).

136 and reject novel spectra that may be neither marijuana nor hemp.

137 reat or moderate risk to health from smoking marijuana occasionally) and marijuana use (past 30 days)

138 fect size=0.14), and lower past month use of marijuana (odds ratio=0.65) and illegal drugs (odds rati

139 To our knowledge, the effect of recreational marijuana on the pediatric population has not been evalu

140 the effects of increased use and potency of marijuana on water and wastewater treatment processes an

141 f perceiving great risk of harm from smoking marijuana once or twice a week decreased from 50.4% (49.

142 e evidence for the legitimate medical use of marijuana or cannabinoids is limited to a few indication

143 eling to determine whether spectra belong to marijuana or hemp and reject novel spectra that may be n

144 Cannabis sativa, also known as marijuana or hemp, produces a non-psychoactive compound

145 ce these spectra are recognized by aSIMCA as marijuana or hemp, they are then routed to the appropria

146 Search criteria included "glaucoma" AND "marijuana" or "cannabinoid" or "CBD." The top 20 Google

147 nited States that reported alcohol, tobacco, marijuana, or other drug use outcomes.

148 ctronic vapor product was used together with marijuana, particularly in combination with cigarette sm

149 ion of great or no risk of harm from smoking marijuana, perception of state legalisation of medical m

150 Historical shifts are occurring in marijuana policy.

151 dose deaths and the changing legal status of marijuana pose new challenges.

152 No evidence was seen for a contribution of marijuana product contaminating bacteria to these differ

153 riving abilities, unintentional ingestion of marijuana products by children, the relationship between

154 Of these, 103 respondents (51%) recommended marijuana products for the treatment of glaucoma.

155 Known marijuana products involved in the exposure included 30

156 of Delta9-THC in the increasingly available marijuana products used by male teens may largely reflec

157 tional marijuana use and authorizing medical marijuana programs, there are renewed clinical and polic

158 , we found that legalization of recreational marijuana reduced the number of searches of white, black

159 methamphetamine/crystal, cocaine/crack, and marijuana, regardless of whether or not abstinence was a

160 The mean rate of marijuana-related visits to the children's hospital incr

161 nsor for the detection of THC in saliva as a marijuana roadside DUI test with a lower detection limit

162 As marijuana's popularity continues to grow, patients with

163 iosynthesis of the endogenous counterpart of marijuana's psychotropic and appetite-inducing component

164 ucoma will encounter conflicting opinions on marijuana's role in glaucoma therapy.

165 The data showed that although the number of marijuana samples seized over the last 4 years has decli

166 The first set contains different marijuana samples with higher concentrations of tetrahyd

167 ant community about whether patients who use marijuana should be eligible for transplant listing, but

168 particularly in people exposed to secondhand marijuana smoke (SHMS).

169 Particles from marijuana smoke are on average 29% larger in mobility di

170 Marijuana smoke contains cannabinoids, immunosuppressant

171 Tobacco and marijuana smoke particles are quantitatively similar in

172 For tobacco and marijuana smoke, respectively, 4350 and 2575 different c

173 Marijuana smokers had higher levels of testosterone with

174 Cigarette or marijuana smoking are infrequently criteria for exclusio

175 Regular marijuana smoking more than once per week was associated

176 Marijuana exposure visits and RPC cases, marijuana source and type, clinical effects, scenarios,

177 n perceiving great risk of harm from smoking marijuana suggest the need for education regarding the r

178 legalization had exposures from recreational marijuana, suggesting that legalization did affect the i

179 al target of the psychoactive constituent of marijuana, the partial agonist Delta(9)-tetrahydrocannab

180 vity ranged from 0.82 (CI, 0.76 to 0.87) for marijuana to 0.63 (CI, 0.47 to 0.78) for sedatives; spec

181 illicit cannabis plant material from regular marijuana to sinsemilla.

182 ts indicated that perceptions of legality of marijuana use (beta, 0.378; 95% CI, 0.205 to 0.444; P <

183 th graders: % [SD], -9.0 [3.8]; P = .02) and marijuana use (eighth graders: % [SD], 5.0 [1.9]; P = .0

184 Perceived harmfulness of marijuana use (great or moderate risk to health from smo

185 coma, past marijuana use, perceptions toward marijuana use (legality, systemic adverse effects, safet

186 lth from smoking marijuana occasionally) and marijuana use (past 30 days).

187 ences were found in perceived harmfulness or marijuana use among 12th graders in Washington or for an

188 ing number of states legalizing recreational marijuana use and authorizing medical marijuana programs

189 The associations between increases in marijuana use and decreases in perceiving great risk of

190 Past-year marijuana use and DSM-IV marijuana use disorder (abuse o

191 adult recreational and prescription drug and marijuana use and experience of sexual violence, feminin

192 Associations between heavy marijuana use and HIV disease markers or white blood cel

193 compared changes in perceived harmfulness of marijuana use and in past-month marijuana use in Washing

194 Marijuana use and legalization are a pressing issue for

195 Recent increases in marijuana use and legalization without adequate knowledg

196 Changes in marijuana use and risk perception generally began in 200

197 vide data examining the relationship between marijuana use and semen quality from young men recruited

198 Thus, understanding trends of marijuana use and use disorders and examining factors th

199 each survey year, we estimated prevalence of marijuana use and use disorders, initiation of marijuana

200 recent and/or cumulative history of regular marijuana use and whether these effects were sustained f

201 education >12 years, and 20% reported heavy marijuana use at >/=50% of biannual visits during follow

202 ders in Washington, perceived harmfulness of marijuana use decreased and marijuana use increased foll

203 g eighth and 10th graders, respectively, and marijuana use decreased by 1.3% and 0.9% over the same p

204 Past-year marijuana use and DSM-IV marijuana use disorder (abuse or dependence).

205 However, the prevalence of marijuana use disorder among marijuana users decreased s

206 nearly 3 of 10 marijuana users manifested a marijuana use disorder in 2012-2013.

207 The past-year prevalence of DSM-IV marijuana use disorder was 1.5% (0.08) in 2001-2002 and

208 2012-2013, and there was a large increase in marijuana use disorders during that time.

209 However, marijuana use disorders in adults remained stable at abo

210 The study of marijuana use disorders is urgently needed because of in

211 ugh it also may detect tobacco, alcohol, and marijuana use disorders, further refinement is needed be

212 uana use, as seen in the lower prevalence of marijuana use each year during 2006-14 than in 2002 when

213 ed whether adolescents who engage in regular marijuana use exhibit a systematic increase in subclinic

214 rceived harmfulness or past-month adolescent marijuana use following legalization.

215 be particularly relevant in states in which marijuana use for glaucoma is legal, as in the case of t

216 As more states approve marijuana use for medical indications, physicians will b

217 and concurrent cigarette use, the effect of marijuana use from time 2 to time 3 remained significant

218 arijuana for medical purposes and adolescent marijuana use has been controversial.

219 severity of glaucoma, prior knowledge about marijuana use in glaucoma, past marijuana use, perceptio

220 rrent practice patterns and attitudes toward marijuana use in patients with advanced heart failure be

221 With rising rates of marijuana use in the general population and an increasin

222 al marijuana use, and mean number of days of marijuana use in the previous year.

223 er states that did not legalize recreational marijuana use in this period.

224 dical community and legislative groups about marijuana use in transplant candidates is needed to ensu

225 ion between the legalization of recreational marijuana use in Washington and Colorado in 2012 and the

226 rmfulness of marijuana use and in past-month marijuana use in Washington and Colorado prior to recrea

227 eighth and 10th graders, respectively, while marijuana use increased 2.0% and 4.1% from 2010-2012 to

228 d harmfulness of marijuana use decreased and marijuana use increased following legalization of recrea

229 Marijuana use increased from 10.4% (95% CI 9.97-10.82) t

230 Prevalence and frequency of marijuana use increased in adults in the USA starting in

231 Heavy marijuana use is a risk factor for CV disease in HIV-inf

232 for recreational use on rates of adolescent marijuana use is a topic of considerable debate.

233 The findings of this study indicate that marijuana use is associated with decreased neural respon

234 Our findings are of public interest as marijuana use is common and may be contributing to recen

235 Importance: Medicinal marijuana use is currently legal in 23 states and the Di

236 Screening for marijuana use is encouraged, especially in young patient

237 Marijuana use is increasing as more states are legalizin

238 Although states where marijuana use is legal have higher rates of use than non

239 begins in adolescence, and heavy adolescent marijuana use is often associated with impaired cognitiv

240 Marijuana use is prevalent among persons infected with h

241 Over time, marijuana use may alter anticipatory reward processing i

242 Marijuana use may alter ventral striatal response to rew

243 These results suggest that regular marijuana use may significantly increase the risk that a

244 The prevalence of marijuana use more than doubled between 2001-2002 and 20

245 Effects of marijuana use on cardiovascular (CV) events and other en

246 some studies showing detrimental effects of marijuana use on cognitive functioning and others showin

247 ion in multiple jurisdictions, the effect of marijuana use on future risk of psychiatric disorders, a

248 influence of perceptions of the legality of marijuana use on intentions to use this substance as a t

249 to date, little data exist on the impact of marijuana use on male fertility.

250 search is needed to determine the effects of marijuana use on neural function involved in reward resp

251 viders regarding the negative association of marijuana use on semen quality.

252 The effect of prior regular marijuana use on subsequent subclinical psychotic sympto

253 nth and lifetime diagnoses, the mean days of marijuana use per year were 225.3 (SE=5.7) and 274.2 (SE

254 Long-term heavy marijuana use showed no significant associations with vi

255 Greater marijuana use was associated with later blunted activati

256 Marijuana use was self-reported at the time of each cogn

257 ent study was to examine the associations of marijuana use with changes in intellectual performance i

258 models were used to test the association of marijuana use with neural response in the NAcc to reward

259 these trends (eg, perceptions of harms from marijuana use) is essential.

260 perception of state legalisation of medical marijuana use, and mean number of days of marijuana use

261 , history of glaucoma, knowledge and rate of marijuana use, and perceptions of marijuana use.

262 ere associated with changes in prevalence of marijuana use, as seen in the lower prevalence of mariju

263 rijuana use and use disorders, initiation of marijuana use, daily or near daily use, perception of gr

264 ng states that did not legalize recreational marijuana use, perceived harmfulness decreased by 4.9% a

265 wledge about marijuana use in glaucoma, past marijuana use, perceptions toward marijuana use (legalit

266 zes cardiovascular considerations related to marijuana use, pharmacological interactions, and future

267 gh school heavy drinking, cigarette smoking, marijuana use, poly-prescription drug misuse, white race

268 Self-reported frequency of marijuana use, subclinical psychotic symptoms, and sever

269 be an increase in health problems related to marijuana use, such as dependence/addiction, psychosis,

270 each year adolescent boys engaged in regular marijuana use, their expected level of subsequent subcli

271 nd rate of marijuana use, and perceptions of marijuana use.

272 eased following legalization of recreational marijuana use.

273 ic variables, disease severity, and previous marijuana use.

274 red questionnaires that include questions on marijuana use.

275 eating disorders, overweight or obesity and marijuana use.

276 tional states that may legalize recreational marijuana use.

277 uding depression; anxiety; conduct problems; marijuana use; optimism; not in education, employment, o

278 (DRN), smoking-and-drinking subjects (SAD), marijuana users (MAR), smoking-and-marijuana users (SAM)

279 ts (SAD), marijuana users (MAR), smoking-and-marijuana users (SAM), marijuana-and-drinking users (MAD

280 We used a cross-sectional study of 20 marijuana users and 19 control non-users, to determine i

281 e prevalence of marijuana use disorder among marijuana users decreased significantly from 2001-2002 (

282 While not all marijuana users experience problems, nearly 3 of 10 mari

283 Marijuana users had lower test scores relative to nonuse

284 na users experience problems, nearly 3 of 10 marijuana users manifested a marijuana use disorder in 2

285 moked more than 20 cigarettes daily, current marijuana users, and those who reported 16 or more lifet

286 um, and Porphyromonas, were at low levels in marijuana users, while Rothia, which is found at depress

287 l states have passed legislation prohibiting marijuana-using patients from being denied transplant li

288 espondents from states with laws prohibiting marijuana-using patients from being denied transplant li

289 nied transplant listing reported denying all marijuana-using patients or mandating abstinence before

290 Furthermore, marijuana-using twins failed to show significantly great

291 to characterize trends in the prevalence of marijuana vaping in 2017, 2018, and 2019 among 8th, 10th

292 mine if chronic inhalation-based exposure to marijuana was associated with a distinct oral microbiota

293 02 when perceiving risk of harm from smoking marijuana was included in models.

294 sary employees were questioned as to whether marijuana was recommended and whether marijuana was safe

295 hether marijuana was recommended and whether marijuana was safe and effective.

296 In contrast to marijuana, where Delta(9)-tetrahydrocannabinol (Delta(9)

297 iol (CBD) is a non-psychoactive component of marijuana, which has anti-inflammatory effects.

298 re are more than 17 million current users of marijuana with 4.6 million using marijuana almost daily.

299 cts of THC.SIGNIFICANCE STATEMENT Strains of marijuana with high levels of delta-9-tetrahydrocannabin

300 A total of 45% had smoked marijuana within the last 3 months.