ライフサイエンスコーパス: mass spectrometric

1 f All Theoretical Fragment Ion Mass Spectra) mass spectrometric acquisitions were performed to obtain

2 Duplicate mass spectrometric analyses and confirmatory next genera

3 matography is a core component of almost all mass spectrometric analyses of (bio)molecules.

4 Tandem mass spectrometric analyses of deuterated congeners and

5 Large-scale microarray and mass spectrometric analyses revealed significant up-regu

6 Therefore, we performed quantitative mass spectrometric analyses to define the epitopes forme

7 We used immunoprecipitation followed by mass spectrometric analyses to evaluate the presence of

8 enable users to perform complex quantitative mass spectrometric analyses with ease.

9 Because of the high-throughput nature of mass spectrometric analyses, the interpretation of these

10 al wisdom that detergents are deleterious to mass spectrometric analyses, the presence of Tween-20 di

11 sterase assay as well as in situ and ex situ mass spectrometric analyses.

12 c antibodies and patients' serum followed by mass spectrometric analyses.

13 Mass-spectrometric analyses confirmed that conversion is

14 -energy collisional dissociation) multistage mass spectrometric analysis (HCD-MS(n)) and ETD (electro

15 Here, amide hydrogen-deuterium exchange with mass spectrometric analysis (HDX-MS) coupled with proteo

16 ater labeling combined with sensitive tandem mass spectrometric analysis allowed integrated synthesis

17 ibrinogen for additional investigation using mass spectrometric analysis and electron microscopy.

18 Performed mass spectrometric analysis and molecular modeling allow

19 ships between BtAdVs and CAdVs, we conducted mass spectrometric analysis and single-particle cryo-ele

20 Mass spectrometric analysis identified apolipoprotein(a)

21 oinducing peptide (AIP) was responsible, and mass spectrometric analysis identified the S. caprae AIP

22 Mass spectrometric analysis identified USP14 interaction

23 Mass spectrometric analysis indicated that 628 cell-lysa

24 Arraying of single cells for mass spectrometric analysis is a considerable bioanalyti

25 he main limitation to the sensitivity of the mass spectrometric analysis of (99)Tc is the background

26 TS-5 degradation products were identified in mass spectrometric analysis of 29 of 33 arthropathic pat

27 A holistic, nontargeted mass spectrometric analysis of any herbal material and p

28 Compared to previous attempts at MALDI-TOF mass spectrometric analysis of barley proteins, the extr

29 st sampling/ionization method for the direct mass spectrometric analysis of biological samples at amb

30 new analytical technique allowing for rapid mass spectrometric analysis of biological samples with l

31 Mass spectrometric analysis of carbonyl compounds in fec

32 Mass spectrometric analysis of cell extracts identified

33 Mass spectrometric analysis of conditioned medium from i

34 conjunction with chemical cross-linking and mass spectrometric analysis of conformational changes to

35 Mass spectrometric analysis of GAG isomers, in particula

36 Our mass spectrometric analysis of homomeric and heteromeric

37 ecent advances in methods for enrichment and mass spectrometric analysis of intact glycopeptides have

38 Mass spectrometric analysis of Ire1 expressed in Escheri

39 best of our knowledge using state of the art mass spectrometric analysis of particle and gas-phase co

40 Finally, using a mass spectrometric analysis of secreted proteins, we dem

41 ntargeted, high throughput, and quantitative mass spectrometric analysis of single cells from cell su

42 While nanofluidic technologies have enabled mass spectrometric analysis of single cells, these measu

43 RNA sequencing and mass spectrometric analysis of SPRIGHTLY-expressing cell

44 Mass spectrometric analysis of the anionic products of i

45 Mass spectrometric analysis of the anionic products of i

46 Using mass spectrometric analysis of the isolated VEGF-C-cleav

47 tion on the digestibility were determined by mass spectrometric analysis of the modified beta-lactogl

48 We conducted a comprehensive mass spectrometric analysis of the N-glycosylation profi

49 tudy, we performed affinity purification and mass spectrometric analysis of the protein microenvironm

50 Raman spectroscopic and mass spectrometric analysis of the reaction solutions re

51 Mass spectrometric analysis of the secretome of P. aerug

52 Mass spectrometric analysis of the starting octasacchari

53 reened for their subsite specificities using mass spectrometric analysis of their products when actin

54 Through mass spectrometric analysis of ubiquitylated proteins af

55 A mass spectrometric analysis platform has been developed

56 mportant role of GNRs as semiconductors, the mass spectrometric analysis provides a readily available

57 which can subsequently be subjected to rapid mass spectrometric analysis providing insights into the

58 Mass spectrometric analysis revealed binding of ZNF768 t

59 Mass spectrometric analysis revealed significant differe

60 Mass spectrometric analysis revealed that the RxLR seque

61 al trypsinolysis followed by high resolution mass spectrometric analysis reveals that Ub chain branch

62 stion of milk proteins by kefir grains, with mass spectrometric analysis showing the release of 609 p

63 has the potential to be translated to other mass spectrometric analysis techniques, including MALDI

64 oupled with a fragment separation method and mass spectrometric analysis to compare their secondary s

65 n to reduce complexity of mixtures or tandem mass spectrometric analysis to conduct structural elucid

66 on to stabilize regiospecificity, and tandem mass spectrometric analysis to identify and quantify reg

67 sources, enzyme assays, Western blotting and mass spectrometric analysis to monitor and quantify the

68 )-based workflow from sample preparation for mass spectrometric analysis to visualization of protein-

69 es from volume-limited samples, each type of mass spectrometric analysis uncovers only a portion of t

70 gent followed by enzyme digestion and tandem mass spectrometric analysis using an LC-MS/MS system cou

71 tified by a combination of NMR spectroscopy, mass spectrometric analysis, and computational modeling

72 design, Co-IP, preparation of the sample for mass spectrometric analysis, and data analysis steps, to

73 Ahead of online mass spectrometric analysis, field asymmetric ion mobili

74 Here, using mass spectrometric analysis, it is demonstrated that the

75 ovalent capture, co-immunoprecipitation, and mass spectrometric analysis, we identified a subset of H

76 and quantified using a targeted HPLC tandem mass spectrometric analysis.

77 ochemistry with peptidomics information from mass spectrometric analysis.

78 determined by chromatographic separation and mass spectrometric analysis.

79 blished by immunohistochemistry staining and mass spectrometric analysis.

80 kground biofluid electrolytes for quantiatve mass spectrometric analysis.

81 MR, (13)C NMR, UV-Vis spectroscopies and via mass spectrometric analysis.

82 latilization with online chemical ionization mass spectrometric analysis.

83 ethylation of glycopeptides and their tandem mass spectrometric analysis.

84 atmospheric pressure chemical ionization and mass spectrometric analysis.

85 from glycoproteins in whole cell lysates for mass spectrometric analysis.

86 nvolving several intermediates identified by mass spectrometric analysis.

87 se positives are small owing to the use of a mass spectrometric analysis.

88 ions that occur during sample preparation or mass spectrometric analysis.

89 f aging mice and followed by biochemical and mass spectrometric analysis.

90 ipidomics has been significantly advanced by mass spectrometric analysis.

91 investigated by end-group analysis with ESI mass spectrometric analysis.

92 en reported, but could not yet be coupled to mass spectrometric analysis.

93 phase as multiply charged ions suitable for mass spectrometric analysis.

94 able rapid affinity purification followed by mass spectrometric analysis.

95 Affinity purification and subsequent mass-spectrometric analysis of Nedd8-conjugated proteins

96 Mass-spectrometric analysis of the enzymatic hydrolysis

97 The concept of direct mass-spectrometric analysis, especially exploited by amb

98 After sample preparation and mass-spectrometric analysis, peptide intensity ratios be

99 Using yeast two-hybrid and mass-spectrometric analysis, we report that mDia1 has a

100 Spectroscopic and mass spectrometric analytical techniques were used to ch

101 We provide mass spectrometric and biochemical evidence of an associ

102 gnificant improvements to total selectivity (mass spectrometric and chromatographic), peak identifica

103 Mass spectrometric and crystallographic studies of Pt(II

104 Mass spectrometric and immunochemical analyses showed th

105 Additionally, mass spectrometric and immunochemical analyses showed th

106 Combined mass spectrometric and infrared spectroscopic analyses o

107 lity of this ion source is demonstrated with mass spectrometric and ion mobility measurements of acet

108 g first catalysis cycle were corroborated by mass spectrometric and NMR experiments, thereby addition

109 Our mass spectrometric and spectroscopic studies are accompa

110 Biochemical, mass spectrometric, and mutational analyses revealed tha

111 Light-scattering, mass spectrometric, and nuclear magnetic resonance chara

112 alternative strategy to the well-established mass spectrometric approach and thus effectively adds to

113 Our high-resolution mass spectrometric approach can unambiguously differenti

114 we report the development of a quantitative mass spectrometric approach combined with microfluidic t

115 For the first time we present a mass spectrometric approach employing an ambient ionisat

116 Notably, a mass spectrometric approach showed that ARH3-deficient m

117 We present a mass spectrometric approach to characterize and monitor

118 Using a large-scale mass spectrometric approach, here we perform quantitativ

119 Here, using a site-specific mass spectrometric approach, we reveal the glycan struct

120 an untargeted, liquid chromatography-coupled mass spectrometric approach.

121 Herein, we highlight mass spectrometric approaches commonly applied to identi

122 g genetic, biochemical, and highly sensitive mass spectrometric approaches, we identified an alternat

123 graphy-multiple reaction monitoring (LC-MRM) mass spectrometric approaches.

124 new lipidomics-based liquid chromatographic-mass spectrometric assay for phospholipases A(2) to perf

125 Herein, the first chiral dopant-based mass spectrometric assay, with its foundation rooted in

126 pared using either flow cytometry or a novel mass spectrometric assay.

127 clearance using liquid chromatography-tandem mass spectrometric assays of serum and timed urine sampl

128 were studied in patients using quantitative mass-spectrometric assays.

129 ctrometric instrumentation was performed for mass spectrometric assessment of trueness.

130 ental mechanistic studies including those of mass spectrometric back reaction screening experiments,

131 Here, we provide mass spectrometric-based evidence to show that metallodr

132 Here, we report chromatographic and mass spectrometric behavior of 904 authentic standards c

133 ledge of specific compound classes and their mass spectrometric behaviour, and poses the risk of miss

134 gained considerable momentum in the field of mass spectrometric biomolecule analysis, including prote

135 Using these improved mass spectrometric capabilities, we detected and quantif

136 Mass spectrometric characterisation identified novel MUP

137 ons upon APCI, and therefore enable accurate mass spectrometric characterization of complex mixtures

138 Mass spectrometric characterization of KRAS expressed in

139 Mass spectrometric characterization of McrA from the met

140 tion curves, herein we present a coulometric mass spectrometric (CMS) approach for absolute protein q

141 s have been observed and characterized under mass spectrometric conditions.

142 direct analysis in real time-high resolution mass spectrometric (DART-HRMS) analysis of ethanol suspe

143 ming), proteomic sample preparation (5-7 d), mass spectrometric data acquisition (2 d), and proteomic

144 construct, proteomic sample preparation, and mass spectrometric data acquisition and analysis.

145 Acquired mass spectrometric data argues against formation of olig

146 ally pretreated samples showed that not only mass spectrometric data can be obtained by electrochemis

147 High-resolution mass spectrometric data collection was conducted in a du

148 efficiently searching liquid chromatographic/mass spectrometric data for unknown compounds has been d

149 extensible OpenMS software implements common mass spectrometric data processing tasks through a well-

150 85 tools and ready-made workflows for common mass spectrometric data processing tasks, which enable u

151 Simplify combines biological and mass spectrometric data sets and uses an "activity index

152 freely available for untargeted analysis of mass spectrometric data sets, it does not always identif

153 ed proteomic sample takes 1 d, acquiring the mass spectrometric data takes 2-5 d and analysis of the

154 However, mass spectrometric data typically contain large amounts

155 Mass spectrometric data was processed using the laborato

156 and polydispersity index determined from the mass spectrometric data were in line with both the label

157 n criteria addressing (1) the quality of the mass spectrometric data, (2) the confidence of peptide i

158 d quantify pGlu, in agreement with available mass spectrometric data.

159 ure is examined on simulated as well as real mass spectrometric data.

160 es in liquid chromatographic high-resolution mass spectrometric data.

161 -linking approaches is the complexity of the mass spectrometric data.

162 phase I/II biotransformation prediction and mass-spectrometric data mining.

163 ional gas chromatography with time-of-flight mass spectrometric detection (GC x GC-TOFMS).

164 (3D) gas chromatography with time-of-flight mass spectrometric detection (GC(3)/TOFMS) is described.

165 ional gas chromatography with time-of-flight mass spectrometric detection (GCxGC/TOFMS) proved to be

166 iation in rice using ion chromatography with mass spectrometric detection (IC-ICP-MS), covering the m

167 ulizer coupled to inductively coupled plasma mass spectrometric detection (ICP-MS).

168 llel high resolution time of flight (HR-ToF) mass spectrometric detection and a high throughput acety

169 lecular beam (CMB) instruments with rotating mass spectrometric detection and time-of-flight analysis

170 igand interaction screening assays employing mass spectrometric detection are widely used in early st

171 ng LK concentrations in their brains using a mass spectrometric detection method developed for this p

172 e that a peptide binding method coupled with mass spectrometric detection of bound peptide can quanti

173 analytes with excellent chromatographic and mass spectrometric detection properties.

174 iltration, microfluidic sample handling, and mass spectrometric detection through signal ion emission

175 and selected reaction monitoring (SRM) based mass spectrometric detection to quantify a positron emis

176 alidated, using liquid chromatography-tandem mass spectrometric detection, in order to accurately det

177 hemical composition distribution (CCD), with mass spectrometric detection, is described.

178 high-performance liquid chromatography with mass spectrometric detection, whereas total phenolic con

179 rption ionization time-of-flight (MALDI-TOF) mass spectrometric detection-are attractive analytical a

180 gh-performance liquid chromatographic-tandem mass spectrometric detection.

181 derable benefits when combined with accurate mass spectrometric detection.

182 ance liquid chromatography (UPLC), both with mass spectrometric detection.

183 pyrolysis coupled to gas chromatography with mass-spectrometric detection in selected ion monitoring

184 tivity assay that allows the high-throughput mass-spectrometric detection of enzyme activity in compl

185 as a versatile ambient ionization source for mass-spectrometric determinations of polar and nonpolar

186 to develop rapid, large-scale, and parallel mass spectrometric drug screens.

187 iven sodium or proton pump, with noncovalent mass-spectrometric, electrophysiological, and flash phot

188 ) complex was also confirmed by electrospray mass spectrometric (ESI MS) experiments.

189 he DS(-) hampers the electrospray ionization mass spectrometric (ESI-MS) analysis.

190 Genetic, pharmacological and mass spectrometric evidence in vivo as well as in vitro

191 ates and products of ACE through a series of mass-spectrometric experiments.

192 ke of any of the 4 same foods.A total of 249 mass spectrometric features showed a positive dose-depen

193 methods for P(A) analysis based on enzymatic mass spectrometric fingerprinting and in silico simulati

194 Here, we describe an enzymatic/mass spectrometric fingerprinting method to analyze the

195 Applicability of the obtained mass spectrometric fingerprints for food authentication

196 ct our predicted hidden states, we use rapid mass spectrometric footprinting and confirm our models'

197 the gas phase using two differential tandem mass-spectrometric fragmentation methods, such as collis

198 A gas chromatography-mass spectrometric (GC-MS) method was utilized for the s

199 S-BID) method, coupled to gas chromatography/mass spectrometric (GC/MS) analysis, was developed for t

200 Hs to channel them into a gas chromatography/mass spectrometric (GC/MS) system for analysis.

201 functional assessment of barrier parameters, mass spectrometric global proteomic analysis and quantit

202 Here, we combine comprehensive mass spectrometric glycan sequencing and molecular dynam

203 However, the mass spectrometric identification and characterization o

204 h thioredoxin in E. coli cells, allowing for mass spectrometric identification of interacting protein

205 ed to explore the utility of this reagent in mass spectrometric identification of specific functional

206 Here we report on the mass spectrometric identification of the OTULIN interact

207 d a biotin tag for subsequent enrichment and mass spectrometric identification of the receptor or oth

208 Here, using affinity protein purification, mass spectrometric identification, and confocal immunofl

209 A modified isotope dilution mass spectrometric (IDMS) method treating the silicon as

210 matrix-assisted laser desorption/ionization mass spectrometric imaging (MALDI-MSI) of agarose micro-

211 Advanced mass spectrometric imaging and surface analysis techniqu

212 Furthermore, we performed mass spectrometric imaging combined with fluorescence in

213 compatibility of this protocol with various mass spectrometric imaging methods including matrix-assi

214 comparison between tandem and time-of-flight mass spectrometric instrumentation was performed for mas

215 Mass spectrometric investigation indicates the presence

216 digestion followed by liquid chromatographic/mass spectrometric (LC/MS) analysis was used to locate "

217 lts demonstrate that combinatory AQbD-guided mass spectrometric/liquid chromatographic optimization s

218 ke the double-spike procedure, only a single mass spectrometric measurement is required, which improv

219 idation of a surrogate peptide combined with mass spectrometric measurement of the oxidation yield.

220 Mass spectrometric measurements both by electrospray ion

221 Additional mass spectrometric measurements of 20 different organic

222 Mass spectrometric measurements revealed that expression

223 in C. beticola and E. fawcettii coupled with mass spectrometric metabolite analyses confirmed their r

224 A major bottleneck of mass spectrometric metabolomic analysis is still the rap

225 sults obtained by inductively coupled plasma mass spectrometric method and no significant difference

226 ted laser desorption/ionization (SALDI)-type mass spectrometric method for analysis and imaging, can

227 A new mass spectrometric method for evaluating metabolite form

228 methods in recent years, there is no simple mass spectrometric method for identification and de novo

229 Finally, we established a mass spectrometric method for quantifying the incorporat

230 of this study were to develop a quantitative mass spectrometric method for selected betainized compou

231 y accessible, sensitive, and robust targeted mass spectrometric method selected reaction monitoring,

232 We report here a mass spectrometric method that is able to identify and d

233 Here we developed a mass spectrometric method to interrogate incorporation o

234 was to apply a liquid chromatography-tandem mass spectrometric method to investigate the presence of

235 alidation of a highly accurate and sensitive mass spectrometric method, no trace of BMAA was detected

236 use model), were identified by an innovative mass spectrometric method, SNOTRAP.

237 tra performance liquid chromatography-tandem mass spectrometric method.

238 as and liquid chromatographies combined with mass spectrometric methods (gas chromatography/mass spec

239 Atmospheric pressure sampling mass spectrometric methods are ideal platforms for rapid

240 9 to 88.6 mumol/h/kg) (P = 0.165) by the two mass spectrometric methods in HC.

241 lemented or largely replaced by a variety of mass spectrometric methods in recent years, there is no

242 to 102.2 mumol/h/kg) (P = 0.247) by the two mass spectrometric methods in SM and 93.7 mumol/h/kg (IQ

243 eled peroxides in association with sensitive mass spectrometric methods should constitute powerful to

244 mponent sample, compared to classical tandem mass spectrometric methods that discard all ions with th

245 itoring tool, this approach could supplement mass spectrometric methods that may only be applicable a

246 Two liquid chromatography-tandem mass spectrometric methods were developed and validated

247 Compared to other mass spectrometric methods, the developed assays require

248 Using two different tandem mass spectrometric methods, we measured the isotopic enr

249 clinical sample cohorts and across different mass spectrometric methods.

250 different in SM than in HC by the respective mass spectrometric methods: 93.2 mumol/h/kg of body weig

251 Comprehensive mass spectrometric (MS) analyses were conducted to chara

252 ent separation method, the addition to it of mass spectrometric (MS) analysis, and recent improvement

253 abundance glycans and glycopeptides prior to mass spectrometric (MS) analysis.

254 ndle for their selective enrichment prior to mass spectrometric (MS) analysis.

255 Mass spectrometric (MS) characterization of these molecu

256 Here, we present a workflow that allows mass spectrometric (MS) identification of proteins in di

257 a laborious and time-consuming process, and mass spectrometric (MS) imaging techniques, which show g

258 A highly sensitive mass spectrometric (MS) method was developed and validat

259 Sensitive and selective mass spectrometric (MS) techniques coupled to ultrahigh

260 Next-generation mass spectrometric (MS) techniques such as SWATH-MS have

261 BS can be applied for the concomitant tandem mass spectrometric (MS/MS) analysis of nine pharmaceutic

262 Here we report synthetic, mass spectrometric, NMR spectroscopic and quantum mechan

263 carryover and improve liquid chromatography-mass spectrometric performance.

264 Mass spectrometric phosphoproteomic measurements further

265 spectrometry (REIMS) was used for the rapid mass spectrometric profiling of cancer cell lines.

266 This may be the first mass spectrometric profiling of polyphenol components fr

267 As an alternative, direct mass spectrometric profiling of the mucosal metabolome p

268 We performed a mass spectrometric proteomics characterization of BALF e

269 d by Proton Transfer Reaction Time-of-Flight Mass Spectrometric (PTR-(ToF)MS).

270 id-catalyzed depurination of DNA followed by mass spectrometric quantification of adenine.

271 , vaporizer) parameters for high-sensitivity mass spectrometric quantification of brain tissue glutam

272 bioanalytical GLP methodology detailing the mass spectrometric quantitation of PF-05212384 dosed as

273 ith 50 muL of plasma resulted in the highest mass spectrometric response.

274 The mass spectrometric results reveal ample oxidative side r

275 e number of structurally similar components, mass spectrometric screens based on high-performance liq

276 2-AA-labeled glycans have increased mass spectrometric sensitivity for their identification

277 cies concentration, and eventually in direct mass spectrometric sensitivity.

278 itope profiling, computational modeling, and mass-spectrometric sequencing of peptidylarginine deimin

279 and get, to some degree, structure-specific mass spectrometric signals.

280 on Fourier transform ion cyclotron resonance mass spectrometric studies, we determined that water was

281 were validated by photoaffinity labeling and mass spectrometric studies.

282 zation methods have an important role in the mass spectrometric study of crude oils and other natural

283 present a hydrogen/deuterium exchange (HDX)-mass spectrometric study of wild type and mutant COMT, c

284 This finding is borne out by mass spectrometric survey of A152T tau phosphorylation i

285 We developed a portable mass spectrometric system ("miniRuedi") for quantificato

286 igh performance liquid chromatography-tandem mass spectrometric system.

287 nalyzed by a newly developed offline aerosol mass spectrometric technique (AMS).

288 g the oligomer growth can be assigned by the mass spectrometric technique.

289 complexes are characterized with UV/Vis and mass spectrometric techniques and reaction rates with cy

290 al composition by using complementary online mass spectrometric techniques in a comprehensive chemica

291 ble with other ambient desorption/ionization mass spectrometric techniques like desorption electrospr

292 d particle-phase products by high-resolution mass spectrometric techniques revealed the formation of

293 ch could easily be implemented in hyphenated mass spectrometric techniques to improve the structural

294 We combined a range of mass spectrometric techniques to unravel the location an

295 ombination of high-resolution separation and mass spectrometric techniques were used to characterize

296 rs for both variants by integrating advanced mass spectrometric techniques with available electron mi

297 trices revealing excellent agreement of both mass spectrometric techniques.

298 ospheric pressure chemical ionization tandem mass spectrometric (UHPLC-APCI-MS/MS) method was develop

299 liquid chromatography with triple quadrupole mass spectrometric (UPLC-QqQ-MS/MS) profiling of phenoli

300 of peptides identified in current bottom-up mass spectrometric workflows, although impressive for hi