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1 genetically variable and adaptive trait, is maternally inherited.
2 conflict, should the mitochondrial genome be maternally inherited.
3 tozoa, and GFP expression in the embryos was maternally inherited.
4 ations in mitochondrial DNA (mtDNA) that are maternally inherited.
5 .2, indicating that defects in this gene are maternally inherited.
6 hers, suggesting that these mutations can be maternally inherited.
7 140Thr in PTPRN2, affected syncope only when maternally inherited.
8 uclear differentiation, either stochastic or maternally inherited.
9 ing revealed a subset of pri-miRNAs that are maternally inherited.
10 with rearrangements < 6 Mb, unless they were maternally inherited.
11 tinalis to show that levels of buffering are maternally inherited.
12 ased thyroid-stimulating hormone levels when maternally inherited.
13 t by an average of 1.83 cm (-0.31 s.d.) when maternally inherited.
14 KCNQ1 influence diabetes susceptibility when maternally inherited.
17 tudies demonstrated preferential loss of the maternally inherited 1p homologue in NBs with 1p loss of
18 t MYCN amplification: 13 had deletion of the maternally inherited 1p, whereas 16 had deletion of the
20 ith autosomal recessive inheritance, 16 were maternally inherited, 5 were autosomal dominant, and 3 w
22 ter of microRNAs (miRNAs) expressed from the maternally inherited allele ("maternally expressed") to
24 olk sac endoderm, which occurs only from the maternally inherited allele in a female embryo, had the
26 d that Ube3a is primarily expressed from the maternally inherited allele in myelinated large-diameter
28 affecting the expression or function of the maternally inherited allele of the ubiquitin-protein lig
30 s multiple non-coding RNAs (ncRNAs) from the maternally inherited allele, including the largest miRNA
32 protein, is expressed predominantly from the maternally-inherited allele and acts to restrict foetal
33 EA gene is imprinted, so that paternally and maternally inherited alleles are differentially expresse
34 s and mammals [3,4], in which paternally and maternally inherited alleles may be differentially expre
36 Cytoplasmic genetic elements are generally maternally inherited, although there are several excepti
38 Naturally occurring activin receptor mRNA is maternally inherited and contains within its 3' untransl
45 ermatogenesis, whereas class II 26G RNAs are maternally inherited and silence gene expression during
46 family showed that the expressed allele was maternally inherited and that the distinct clinical pres
47 a also suggest that JME may be predominantly maternally inherited and that the HLA-linked form is mor
48 ated into the cotton chloroplast genome were maternally inherited and were not transmitted via pollen
49 guided by the coordinated interplay between maternally inherited and zygotically manufactured RNAs a
50 rray of diverse disorders, most of which are maternally inherited, and all of which are associated wi
51 female-biased line, sex ratio distortion was maternally inherited, and occurred in conjunction with a
56 s and proteins from the aphid's obligate and maternally inherited bacterial endosymbiont, Buchnera, w
60 mmon form of reproductive sabotage caused by maternally inherited bacterial symbionts of arthropods.
61 infection of Drosophila melanogaster by this maternally inherited bacterium restores fertility to fem
62 er's hereditary optic neuropathy (LHON) is a maternally inherited blinding disease characterized by d
64 e its ligand, HLA-C2, was paternally but not maternally inherited by a fetus (p = 0.005, odds ratio =
65 a duplication of seven base pairs, which was maternally inherited, c.844_851dupCCATGCA, predicting p.
67 Although present in a variety of eukaryotes, maternally inherited characters are especially prominent
70 iparentally inherited nuclear loci and three maternally inherited chloroplast fragments from all dipl
72 D/MPV that arose de novo specifically on the maternally inherited chromosome and delete lung-specific
73 we show that deletion of the IG-DMR from the maternally inherited chromosome causes bidirectional los
74 on, the IG-DMR, which is unmethylated on the maternally inherited chromosome, is necessary for the re
75 H19 is expressed almost exclusively from the maternally inherited chromosome, while Igf2 expression i
84 ces with blue eggs are distinguished only by maternally inherited components of the genome, which mai
85 of the X chromosome evoke the P cytotype, a maternally inherited condition that regulates the P-elem
86 nd TP6 are associated with the P cytotype, a maternally inherited condition that represses P-element-
87 genomes and also by having the P cytotype, a maternally inherited condition that strongly represses P
88 ising from loss-of-function mutations in the maternally inherited copy of the UBE3A gene, and is char
89 l disorder caused by loss of function of the maternally inherited copy of UBE3A, an imprinted gene ex
91 3, 4, or 5 unlinked autosomal markers with a maternally inherited cytoplasmic marker illustrate how n
92 e M. pyrifera genotype for two predominantly maternally inherited cytoplasmic markers (COI and rbcLS
94 enriched regions on Chr X, within which rare maternally-inherited damaging variants carry substantial
95 c acidosis and stroke-like episodes (MELAS), maternally inherited deafness and diabetes (MIDD) and pr
96 well as the precise pathogenic mechanism of maternally inherited deafness and its exacerbation by en
97 ritical insights into the pathophysiology of maternally inherited deafness arising from tRNA mutation
100 A methylation-dependent retrograde signal in maternally inherited deafness pathology and shedding sig
101 ked to mitochondrial dysfunctions leading to maternally inherited deafness, aminoglycoside sensitivit
104 Here, we show that pigs (Sus scrofa) with a maternally inherited deletion of UBE3A (UBE3A(-/+)) have
105 phenotype was seen with either paternally or maternally inherited deletions and with either complete
106 w that germ cells can be specified either by maternally inherited determinants (preformation) or by i
108 consistent family relationships (n = 7), and maternally inherited diabetes and deafness (n = 5).
109 causes retinal degeneration in patients with maternally inherited diabetes and deafness and mitochond
112 ffected father, but this is not explained by maternally inherited diabetes and/or deafness (MIDD) cau
113 syndrome, the low mtDNA heteroplasmy causes maternally inherited diabetes with or without deafness (
115 tions in mitochondrial genes as the cause of maternally inherited diseases affecting tissues that rel
116 new insights into the molecular mechanism of maternally inherited diseases and a step toward therapeu
117 tDNA often lead to clinically heterogeneous, maternally inherited diseases that display different org
118 Mutations in mitochondrial DNA (mtDNA) cause maternally inherited diseases, while somatic mutations a
119 gh frequencies of pathogenic mtDNA result in maternally inherited diseases; maternally and somaticall
120 cidosis, and stroke-like episodes (MELAS), a maternally inherited disorder, is usually associated wit
125 Approximately 3-5% of ASD cases arise from maternally inherited duplications of 15q11.2-q13.1, term
127 s suggest that PGCs are unable to respond to maternally inherited endoderm determinants because RNAPI
130 acellular bacteria in the animal kingdom are maternally inherited endosymbionts of the genus Wolbachi
132 tracellular Wolbachia bacteria are obligate, maternally-inherited, endosymbionts found frequently in
134 (IIT)-which uses sterilization caused by the maternally inherited endosymbiotic bacteria Wolbachia-is
135 Progress has been made in developing the maternally inherited endosymbiotic bacterium Wolbachia a
136 Arthropods, including insects, often harbor maternally inherited endosymbiotic microbes, some of whi
137 ited CNVs, specifically for small (<100 kb), maternally inherited events (P = 0.01) that are enriched
138 er's hereditary optic neuropathy (LHON) is a maternally inherited eye disease due to mitochondrial DN
139 d selection, demographic history, and/or any maternally inherited factor such as the bacterial symbio
140 We show that the sea star first likely uses maternally inherited factors and the Wnt and Delta pathw
142 Mutational analysis of COL17A1 identified a maternally inherited G-to-T transversion at the -1 posit
144 enomes suggest the presence of a continuous, maternally inherited gene flow from different regions of
145 inherited genes might be inactivated because maternally inherited genes are adapted to function harmo
146 act of the genetics of the mother beyond the maternally inherited genes can lead to new insights into
148 Mitochondrial diseases include a group of maternally inherited genetic disorders caused by mutatio
149 , using the D-loop of mitochondrial DNA as a maternally inherited genetic marker, we address the ques
150 length polymorphism (RFLP) analysis of three maternally inherited genomes (mitochondrial DNA and plas
151 tance dispersal) on the genetic structure of maternally inherited genomes and the colonization rate o
152 d systems such as Drosophila and Xenopus use maternally inherited germ determinants to specify germ c
154 se observations suggest that Gryllus lacks a maternally inherited germ plasm, in contrast with many h
155 at growth hormone deficiency associated with maternally inherited gingival fibromatosis is an allelic
158 ce lessened toward term, overall, mothers of maternally inherited H19(Delta13) mutants had significan
160 syndrome region on chromosome 15q, which, if maternally inherited, has been implicated in autism.
166 at trophoblast expresses both paternally and maternally inherited HLA-C surface proteins and that mat
168 cular basis of the disorder by identifying a maternally inherited, homoplasmic m.14674T>C mt-tRNA(Glu
169 according to extreme geographic structure in maternally inherited host mitochondrial DNA, appeared co
171 the same region of paternally inherited and maternally inherited human chromosome 15q, respectively.
172 CF, which binds at multiple sites within the maternally inherited ICR and is required to form a chrom
174 though a less likely possibility is that the maternally inherited imprinting center acts in trans in
175 n blotting and RT-PCR, Xenopus TIMP3 mRNA is maternally inherited in eggs and midblastula (stage 8) e
178 this limitation, since the plastid genome is maternally inherited in most plants, motivating the need
179 e DNA-containing cytoplasmic organelles, are maternally inherited in the majority of angiosperm speci
181 ion of a Drosophila simulans population by a maternally inherited insect bacterial parasite, Wolbachi
184 aoronymphium and its sister species harbor a maternally inherited intracellular bacterial symbiont.
187 drial inhibitors, or in neurons derived from maternally inherited Leigh syndrome (MILS) patient iPS c
188 S), neuropathy, ataxia, retinitis pigmentosa-maternally inherited Leigh syndrome (NARP-MILS), and Leb
191 hy, ataxia, and retinitis pigmentosa), MILS (maternally inherited Leigh's syndrome), and FBSN (famili
194 nal identity-by-descent sharing, whereas the maternally inherited locus was not linked to the trait (
195 cluding NRXN2 and CNTNAP2 putatively overlay maternally inherited loss-of-function coding variations
197 duce severe neuromuscular pathologies, cause maternally inherited metabolic diseases, and suppress ap
198 t period owes to conflict, between a woman's maternally inherited (MI) and paternally inherited (PI)
202 t chirality of this drug response suggests a maternally inherited, microfilament-dependent organizati
207 approximately 1500 genes, 37 encoded by the maternally inherited mitochondrial DNA (mtDNA) and the r
211 pulation differentiation was much higher for maternally inherited mitochondrial DNA polymorphisms tha
212 oward creating embryos free from the risk of maternally inherited mitochondrial DNA-based disease.
214 ow is much stronger in nuclear genes than in maternally inherited mitochondrial genes, indicating tha
220 pment depends heavily on accurate control of maternally inherited mRNAs, and yet it remains unknown h
223 Our data thus demonstrate that low levels of maternally inherited mtDNA mutations when present during
225 equilibrium) of associations was greater for maternally inherited mtDNA than for paternally inherited
227 r the genetics of the thousands of copies of maternally inherited mtDNA, the more than 1,000 nuclear
229 phenotyping showed that animals possessing a maternally inherited mutation (Ube3a(mQ606E)) paradoxica
230 otal of 10 de novo mutations and 3 X-linked (maternally inherited) mutations that had been previously
231 ne mutation at position 1555 associated with maternally inherited non-syndromic deafness and sensitiv
232 s in CEP104; one of these subjects harbors a maternally inherited nonsense mutation (c.496C>T [p.Arg1
233 rRNA gene of human mitochondrial DNA causes maternally inherited, nonsyndromic deafness, an extreme
234 tions that disrupted a gene, 82% were either maternally inherited or de novo (p = 4.3 x 10(-3)).
235 n-dependent depletion score=29), each with a maternally-inherited or de novo candidate modifier varia
239 ents required for enhanced expression of the maternally inherited p57 (KIP2) allele lie at a distance
241 ere, we describe an IDAIL proband carrying a maternally inherited pathogenic CTLA4 variant and a pate
242 compound heterozygous for MYO15A variants-a maternally-inherited pathogenic stop-gain variant co-seg
243 led from paternally inherited centrioles and maternally inherited pericentriolar material (PCM) [1].
244 urce loci is determined by histone marks and maternally inherited piRNAs, but also imply the existenc
246 estigations are required to characterize the maternally inherited plant stress imprints leading to hi
247 Recent phylogenomic analyses based on the maternally inherited plastid organelle have enlightened
248 l library, which may reflect an abundance of maternally inherited pre-formed ribosomes in the yolk.
250 Lrmp is a conserved vertebrate gene whose maternally inherited products are essential for nucleus-
255 tic distances, population structure, and the maternally inherited rbcL gene identified putative hybri
257 ound to be conferred non-canonically through maternally inherited repressive histone modification H3K
262 osphorylation are present in a pedigree with maternally inherited sensorineural deafness, levodopa-re
263 To this end, the nature and genetics of the maternally inherited sex-ratio trait of Drosophila bifas
267 severely reduced fertility due to a lack of maternally inherited Stella-protein in their oocytes.
271 ex ratio in offspring under the influence of maternally inherited symbionts, but extreme sex ratios o
272 The early Xenopus embryo expresses three maternally inherited Tcf/LEF mRNAs, and their relative r
273 Since they inhabit the cytoplasm and are maternally inherited, these microorganisms can enhance t
275 l., 2016) we showed that dormancy levels are maternally inherited through the preferential maternal a
276 ondrial DNA (mtDNA) has been associated with maternally inherited traits of hypersensitivity to strep
277 irect consequence of delayed turnover of the maternally-inherited transcription factor LIN-15B, a syn
278 use embryo is associated with destruction of maternally inherited transcripts, an important process f
280 ome (AS), which is caused by the loss of the maternally inherited UBE3A allele (encoding ubiquitin pr
281 rogenetic disorder caused by deletion of the maternally inherited UBE3A allele and is characterized b
285 umption defects specifically associated with maternally inherited Ube3a deficiency may reveal importa
286 analyses identified co-regulated networks in maternally inherited Ube3a deletion offspring enriched i
288 opmental disorder caused by mutations in the maternally inherited UBE3A gene, which encodes a ubiquit
290 used by disrupted neuronal expression of the maternally inherited Ube3A ubiquitin protein ligase, req
291 ter from its enhancers occurs by CTCF in the maternally inherited unmethylated chromosome but not the
292 ) individuals were males, 17 of which have a maternally inherited variant; six individuals (4 male, 2
293 individuals from 26 families with de novo or maternally inherited variants in the X-linked SMARCA1 ge
294 uced in schizonts and female gametocytes, is maternally inherited where its absence leads to the deve
295 9.9 kb of upstream DNA when this deletion is maternally inherited, with synchronous replication patte
297 n brood hatch and promotes the spread of the maternally inherited Wolbachia infection into the host p
298 udy identified preferential selection of the maternally inherited X chromosome in glutamatergic neuro