ライフサイエンスコーパス: matrix metalloproteinase 13

1 chemokine (C-X-C motif) ligand 9 (CXCL9) and matrix metalloproteinase 13.

2 ng did not prevent collagen I degradation by matrix metalloproteinase 13.

3 ed with the expression profiles of DDR-2 and matrix metalloproteinase 13.

4 roteinase 1, matrix metalloproteinase 2, and matrix metalloproteinase 13.

5 such as transforming growth factor-beta2 and matrix metalloproteinase-13.

6 ey are heterogeneous regarding expression of matrix metalloproteinase-13.

7 shly isolated hepatic stellate cells express matrix metalloproteinase-13.

8 synovial fluid CSF1-R levels correlated with matrix metalloproteinase 13, a prognostic marker and mol

9 synovial fluid CSF1-R levels correlated with matrix metalloproteinase 13, a prognostic marker and mol

10 d expression of catabolic factors, including matrix metalloproteinase-13, accompanied by an increase

11 nally, nebulized hypertonic saline inhibited matrix -metalloproteinase-13 accumulation in the broncho

12 ention, sustained gene silencing and reduced matrix metalloproteinase 13 activity over 30 days, resul

13 mediated induction by KC of type X collagen, matrix metalloproteinase-13, alkaline phosphatase, and c

14 ATRA increased the levels of matrix metalloproteinase 13 and aggrecanase activity in

15 pression of matrix-degrading enzymes such as matrix metalloproteinase 13 and aggrecanase.

16 lagen breakdown via the direct activation of matrix metalloproteinase-13 and possibly other fibrillar

17 ramatic up-regulation and down-regulation of matrix metalloproteinase-13 and vascular endothelial gro

18 These cells delivered matrix metalloproteinases-13 and -9, respectively, into

19 Recent work identified matrix metalloproteinase 13 as a myeloma-derived fusogen

20 the activation of the fibrillar collagenase, matrix metalloproteinase-13, by keratinocytes.

21 Matrix metalloproteinase-13 (collagenase-3), a member of

22 tinocytes use an alternative plasminogen and matrix metalloproteinase-13-dependent pathway for dissol

23 -1 and -2, suggesting that plasmin activates matrix metalloproteinase-13 directly.

24 uce chondrocyte hypertrophy and ADAMTS-4 and matrix metalloproteinase 13 expression.

25 an optimized small interfering RNA targeting matrix metalloproteinase 13 for preferential delivery to

26 carrying small interfering RNA targeting the matrix metalloproteinase 13 gene (Mmp13), which breaks d

27 ly upregulated procollagen, fibronectin, and matrix metalloproteinase-13 genes.

28 Human matrix metalloproteinases-13 (HMMP13) shows a wide subst

29 einases revealed significant upregulation of matrix metalloproteinase 13 in Col1a1(r/r) wounds, but m

30 mouse models by increasing the expression of matrix metalloproteinase 13 in M1-TAMs.

31 necrosis factor alpha, IL-1beta, IL-10, and matrix metalloproteinase 13 in the joint to the same ext

32 The activation of matrix metalloproteinase-13 in normal keratinocytes was

33 tein receptor, retinoic acid receptor gamma, matrix metalloproteinase 13, Indian hedgehog, osteocalci

34 nt of beta-catenin cAct mice with a specific matrix metalloproteinase 13 inhibitor, ameliorated the m

35 hoalveolar lavage protein, shock vs. shock + matrix metalloproteinase-13 inhibitor CL-82198, p = .002

36 ic saline, p = .009) and pretreatment with a matrix metalloproteinase-13 inhibitor was sufficient to

37 midin-4-ones 9 as orally active and specific matrix metalloproteinase-13 inhibitors were discovered f

38 ifugation of co-cultured cells revealed that matrix metalloproteinase-13 is localized mainly within h

39 Collagenase-3 (matrix metalloproteinase-13) is expressed by osteoblasts

40 ion of collagen I protein with no changes in matrix metalloproteinase 13 (MMP 13).

41 ether S100A4 can stimulate the production of matrix metalloproteinase 13 (MMP-13) by articular chondr

42 Matrix metalloproteinase 13 (MMP-13) expression was dete

43 Matrix metalloproteinase 13 (MMP-13) has attracted atten

44 Matrix metalloproteinase 13 (MMP-13) has been shown to b

45 Alterations in type X collagen and matrix metalloproteinase 13 (MMP-13) in articular chondr

46 o found increased expression and activity of matrix metalloproteinase 13 (MMP-13) in the mutant mouse

47 ed to evaluate Smad3 and Runx2 regulation of matrix metalloproteinase 13 (MMP-13) messenger RNA (mRNA

48 The ability of S100B and HMGB-1 to stimulate matrix metalloproteinase 13 (MMP-13) production was also

49 on 740 (Y740A), and luciferase driven by the matrix metalloproteinase 13 (MMP-13) promoter were trans

50 age and to stimulate chondrocytes to produce matrix metalloproteinase 13 (MMP-13) through activation

51 Expression of DDR-2, matrix metalloproteinase 13 (MMP-13), and MMP-derived ty

52 nd selective inhibitors (10d and (S)-17b) of matrix metalloproteinase 13 (MMP-13).

53 d its novel role as an essential mediator of matrix metalloproteinase-13 (MMP-13) expression during t

54 Osteoarthritic chondrocytes secrete matrix metalloproteinase-13 (MMP-13) in response to inte

55 Matrix metalloproteinase-13 (MMP-13) is a zinc-dependent

56 Matrix metalloproteinase-13 (MMP-13) is an important enz

57 Matrix metalloproteinase-13 (MMP-13) plays a critical ro

58 The collagenase matrix metalloproteinase-13 (MMP-13) plays an important

59 reported that HDAC4 was a basal repressor of matrix metalloproteinase-13 (MMP-13) transcription and p

60 Previously we reported that PTH induces matrix metalloproteinase-13 (MMP-13) transcription in os

61 Matrix metalloproteinase-13 (MMP-13), a catabolic cartil

62 broblasts, we measured the effect of IL-6 on matrix metalloproteinase-13 (MMP-13), c-jun, junB, and c

63 ranslated region corresponding to the canine matrix metalloproteinase-13 (MMP-13), collagenase-3 gene

64 er (BIK), migration-inhibitory factor (MIF), matrix metalloproteinase-13 (MMP-13), fibroblast growth

65 One of these genes is matrix metalloproteinase-13 (MMP-13), which is involved

66 of basic fibroblast growth factor (bFGF) and matrix metalloproteinase-13 (MMP-13).

67 o zebrafish model to show that the epidermal matrix-metalloproteinase 13 (MMP-13) induces degeneratio

68 nocytes, but not axons, and up-regulation of matrix-metalloproteinase 13 (MMP-13, collagenase 3) in t

69 Collagenase-3 (matrix metalloproteinase 13, MMP-13) was employed as a s

70 and production of interstitial collagenase (matrix metalloproteinase-13; MMP-13), a critical enzyme

71 or 23 (FGF23) expression and FGFR1 activity; Matrix metalloproteinase 13 (MMP13) and Aggrecanase2 (AD

72 real-time PCR was used to measure COL2A1 and matrix metalloproteinase 13 (MMP13) gene expression; Wes

73 expression of type X collagen (Col10a1) and matrix metalloproteinase 13 (Mmp13) genes is decreased.

74 PTH stimulates expression of matrix metalloproteinase 13 (MMP13) in bone.

75 The major metalloproteinase matrix metalloproteinase 13 (MMP13) is also associated w

76 We report that the matrix metalloproteinase 13 (MMP13) is the highest up-re

77 xtracellular matrix (ECM) by the collagenase matrix metalloproteinase 13 (MMP13) represents a key eve

78 xpress more bone-resorbing enzymes including Matrix metalloproteinase 13 (Mmp13) when they generate s

79 We identified matrix metalloproteinase 13 (MMP13), receptor activator

80 Matrix metalloproteinase 13 (Mmp13, collagenase-3) plays

81 Matrix metalloproteinase-13 (MMP13) is a collagenase exp

82 Matrix metalloproteinase-13 (MMP13) is a Zn(2+)-dependen

83 This study investigated whether matrix metalloproteinase-13 (MMP13) is involved in P. ae

84 ddition to the 3'-untranslated region of the matrix metalloproteinases-13 (MMP13) gene, the different

85 his communication we show that expression of matrix metalloproteinase-13 mRNA is reciprocally modulat

86 late cells are co-cultured with hepatocytes, matrix metalloproteinase-13 mRNA is up-regulated and alp

87 tocytes with galactosamine further increased matrix metalloproteinase-13 mRNA production.

88 pport the notion that alpha1(I) collagen and matrix metalloproteinase-13 mRNAs are reciprocally modul

89 imultaneously produce alpha1(I) collagen and matrix metalloproteinase-13 mRNAs.

90 sequence for HMMP13 is 86% identical to rat matrix metalloproteinases-13 (RMMP13); however, the regu

91 the immunoreactivity of type X collagen and matrix metalloproteinase-13 were seen between the groups