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1  nonreceptor-mediated lytic activity at this maximal concentration.
2 IL-1beta cytotoxicity even at 300 pg/ml, the maximal concentration.
3 ed, reaching 20% (median, 5%) of the initial maximal concentration.
4  (median, 13%), respectively, of the initial maximal concentrations.
5 P being the most potent agonist tested (half-maximal concentration, 0.13 microM) and 10-fold more pot
6 ve rather than additive or potentiating with maximal concentrations (100 nM) of EGF, suggesting that
7 thylene-ATP mimicked the action of ATP (half-maximal concentrations 6 and 161 microM, respectively).
8  of CTL019 in peripheral blood, with greater maximal concentration and area under the curve values co
9 t dose-proportional increase in tirapazamine maximal concentration and area under the curve(last) was
10 )C-labeled peptides, 3F(14) reaches a higher maximal concentration and has a longer half-time of elim
11 Cmpk by salicylate and GdCl3 revealed a half-maximal concentration and Hill coefficient of 1.6 mM and
12 (V)2.2 channels, guangxitoxin (GxTX)-1 (half-maximal concentration approximately 1 nmol/l), has been
13 t the apoE4 folding intermediate reached its maximal concentration ( approximately 90% of the mixture
14 y) after acute cocoa consumption and reached maximal concentrations by 2 h (41 +/- 4 nmol/L, 5.92 +/-
15 ha-tocopherol AUC from 0 to 72 h, as well as maximal concentrations (Cmax: 2.04 +/- 0.14 compared wit
16 pendent and partially reversible with a half-maximal concentration constant IC(50) of 2.6 microm.
17 ximal current density and increased the half-maximal concentration derived from GABA dose-response cu
18 e reactions oscillate accordingly, attaining maximal concentration during the middle of their respect
19 tions do not affect the Km for ATP, the half-maximal concentration (EC50) for the C2 domain of type I
20 larly by PUVA following PAR1 (effective half-maximal concentration (EC50), 8.4 +/- 1.1 versus 4.3 +/-
21 exhibit potent inhibitory activity with half-maximal concentrations (ED50) of 320 nM and 460 nM, resp
22 by homoduplex and heteroduplex DNA, the half-maximal concentration for activation by heteroduplex DNA
23 ment ends in direct binding assays; the half-maximal concentration for binding of adducin to gelsolin
24                  The observed geometric mean maximal concentration for linezolid was 6425 ng/mL.
25                            However, the half-maximal concentration for P(i) binding to metalloenzyme
26 tion tendency, secondary structure, and half-maximal concentration for supramolecular assembly, chann
27                                     The half-maximal concentration for this effect was 6.4 nM, with m
28 07 serum concentrations remained stable near maximal concentration for up to 3 years of follow-up.
29                                         Half-maximal concentrations for FFA-induced reduction of junc
30 ols, in a dose-dependent manner, with a half-maximal concentration (IC50) value of 8 micromol/l.
31 in response to both LPS and TNF, with a half-maximal concentration in the range of 0.1 to 0.6 microM.
32 ATP occurred more rapidly and reached higher maximal concentrations in the mitochondria of micu mutan
33 + concentration exceeds 3 microM, and a half-maximal concentration is produced at a free Ca2+ concent
34 scence with a Hill coefficient of 2 and half-maximal concentration (K(Na)(0.5)) of 49 mM at -90 mV.
35 he Hill equation to yield values of the half maximal concentrations (K1/2), and the Hill coefficients
36                      The data yielded a half-maximal concentration, K1/2 = 19 +/- 3 mM and a Hill coe
37  of #x223c;40%, and when applied together at maximal concentrations, no additional spine loss resulte
38 is in the purified Q783A mutant, with a half-maximal concentration of 0.06 micrometer, essentially id
39 that was concentration dependent with a half-maximal concentration of 1 nM.
40  36% at the hMC4R, and 11% at the hMC5R at a maximal concentration of 10 microM.
41 that was concentration dependent with a half-maximal concentration of 2 nM.
42 urrent by 75% (Kd = 3.3 mM, 5 cells) while a maximal concentration of 4-aminopyridine (4-AP; 10 mM) b
43 rrent in a dose-dependent manner with a half-maximal concentration of 4.6 +/- 0.5 mm.
44 48.6% in the presence of ethanol with a half-maximal concentration of 4.7 mM.
45  a specific and saturable manner with a half-maximal concentration of 8 nM.
46 significant endothelial toxic effects at the maximal concentration of amphotericin B.
47 lts in a transient pulse of cAMP, reaching a maximal concentration of approximately 10 microm and per
48     The peptide inhibited fusion with a half-maximal concentration of approximately 2 microM; however
49 nhibited by extracellular Ca(2+) with a half-maximal concentration of approximately 20 mum.
50 ve and insensitive myeloma cells with a half maximal concentration of approximately 3 micromol/L.
51                         In the presence of a maximal concentration of ATP, both the amount of secreti
52 se phospholipid vesicles and lowers the half-maximal concentration of calcium needed for this fusion
53    Activation of muscarinic receptors with a maximal concentration of carbachol (100 microm) induced
54  the leached cobalt ions does not exceed the maximal concentration of cobalt at the NC surface indica
55                     Experiments using a half-maximal concentration of DAMGO demonstrate that nor-BNI
56 is of serum-free C6 culture media revealed a maximal concentration of DARP by culture day 1.
57 zed platelets (150 x 10(3)/microl), the half-maximal concentration of FVIII required to accelerate VW
58                              Dialysis with a maximal concentration of inositol 1,4,5-trisphosphate (I
59 radient increased flash frequency, whereas a maximal concentration of nigericin (5 mum) collapsed the
60                                       A near maximal concentration of the selective 5-HT(2A) antagoni
61 Data were compared to exocytosis evoked by a maximal concentration of the strong secretagogue ionomyc
62    After a single oral dose, the mean +/- SD maximal concentration of thiamine and net area under the
63                                              Maximal concentration of tumor necrosis factor (TNF)-alp
64                 We found previously that the maximal concentration of ultraviolet B radiation (290-32
65                                          The maximal concentration of virus shedding was higher for p
66 r IXa complex in a biphasic manner with half-maximal concentrations of 0.2 and 1.6 mM while the micel
67 2+ inhibited purinoceptor currents with half-maximal concentrations of 5 mM at the P2X2 receptor, 89
68 reased the amplitude of current activated by maximal concentrations of 5-hydroxytryptamine (5-HT) and
69  pronounced intracellular NO elevation, with maximal concentrations of 7 and 17 nm, respectively.
70                                          Yet maximal concentrations of all AngsFvs elicited angiogene
71                            Co-treatment with maximal concentrations of either IGF-1 or BDNF enhanced
72 eased by more than 2-fold in the presence of maximal concentrations of either of the inhibitors of TG
73                                          The maximal concentrations of genomic and replicative-interm
74 4-GFP translocation at either sub-maximal or maximal concentrations of insulin.
75                               The effects of maximal concentrations of lithium and valproate on gluta
76 ctivity was independent of cGMP and the half-maximal concentrations of NADP and NA needed were about
77                           The geometric mean maximal concentrations of PNU-100480, PNU-101603, and PN
78                                              Maximal concentrations of serum SLPI correlate significa
79                      The effects elicited by maximal concentrations of the A2aR agonist 2-[4-(2-carbo
80                                              Maximal concentrations of the MOR-selective agonist DAMG
81 Cl- cotransport 80% to 89% of stimulation by maximal concentrations of these drugs.
82    Similar peak responses were observed with maximal concentrations of these four agonists and with t
83 owed the same trend as fumarate reaching its maximal concentration on the 3rd-5th day after thawing (
84                                              Maximal concentrations ranged from 2.2 to 2.8 and 1.5 to
85 hesion-dependent oxidative burst with a half-maximal concentration similar to that for adhesion.
86 left [L] = 2.9 +/- 1.5 min, the time of half maximal concentration [T1/2max] R = 8.8 +/- 3.7 min, T1/
87 sfully obtained in healthy rats (the time of maximal concentration [Tmax] right [R] = 2.8 +/- 1.2 min
88  area under the concentration-time curve and maximal concentration values increased linearly with dos
89                             Maximal and half-maximal concentrations were approximately 20 and approxi
90 lease rate decreased (2-10 ng/day) and lower maximal concentrations were observed (1-10 micrograms/ml
91 zed at about day 3 of development, reaches a maximal concentration with the formation of the first-st