戻る
「早戻しボタン」を押すと検索画面に戻ります。 [閉じる]

コーパス検索結果 (１語後でソート)

通し番号をクリックするとPubMedの該当ページを表示します
1 er, one serine is bound to each interface at maximal effect.
2 ing was observed, with spermine exerting the maximal effect.
3 otency and, in the case of propofol, reduced maximal effect.
4  had to be added within the first 24 h for a maximal effect.
5 ,5)P3 was more potent and exhibited a larger maximal effect.
6  with IFN-gamma for at least 8 h to obtain a maximal effect.
7 tration-response relationship with 1.9 log10 maximal effect.
8 activate G protein with no alteration in the maximal effect.
9 agnitude without significantly affecting the maximal effect.
10 on stimulation of FGF8b are required for the maximal effect.
11 types of maltreatment at specific ages exert maximal effects.
12 s, and levels of intake optimized to produce maximal effects.
13 ypophysial BK channel activity (EC50, 22 mM; maximal effect, 100 mM).
14 sidue mutated to cysteine (voltages for half-maximal effect -107, -94 and -73 mV for positions 361, 3
15 e NO donor sodium nitroprusside reduced tau (maximal effect, -14+/-2%, n=5, P<0.001), and this lusitr
16                                  The time to maximal effect (20, 50, and 90 min) and duration of effe
17 th intrapulmonary IL-1beta production with a maximal effect 7 days after instillation of the adenovir
18                                          The maximal effect (80 +/- 6% reduction in probability of fi
19  are standardized from 0 (no effect) to 100 (maximal effect); a scale score is the average of respons
20 e Bmax of scuPA binding 4-fold with the half-maximal effect achieved at a peptide concentration of 50
21 ted G1 phase progression within 12 h, with a maximal effect after 72 h.
22 ein expression by >90% with maximal and half-maximal effects after 8 and 2 h, respectively.
23 of the core increased with temperature, with maximal effect around 116 degrees C.
24 tter-gated ion channels have a wide range of maximal effects as well as Hill slopes, suggesting that
25 e suggest thresholds of > 40 Gy s(-1) with a maximal effect at > 100 Gy s(-1), accumulated evidence s
26 imum (6.6 +/- 1.4)-fold increase with a half-maximal effect at 0.3 nM.
27 e slower as [MgADP] was increased, with half-maximal effect at 0.5 mM [MgADP]; the pre- and post-T-ju
28  an EC(50) of approximately 245 nM and had a maximal effect at 0.5-2 microM and required the presence
29 id hydrolysis stimulated by basic FGF with a maximal effect at 1 microg ml-1.
30 phine was concentration-dependent, reached a maximal effect at 1 micromol/L, and was reversed by nalo
31 sponse to TGF-beta1 was dose-dependent, with maximal effect at 1 ng/mL, and was associated with immun
32 ndent inhibition of the lectin pathway, with maximal effect at 10 microg/mL.
33 eversible and concentration dependent with a maximal effect at 10 microM.
34 e-dependent decreases in retinal blood flow (maximal effect at 10(-)(6) M, P < 0.05).
35 TPase activity of ABCR 3-4-fold, with a half-maximal effect at 10-15 microM.
36 hypoxia and simulate preconditioning, with a maximal effect at 100 nM.
37 xpression, as did rosiglitazone, with a half-maximal effect at 100 nm.
38 sient model of ocular hypertension, with the maximal effect at 120 min post-administration at 1% w/v
39 resistance in a dose-dependent manner with a maximal effect at 120 minutes of 6.8 Omega whereas VEGF-
40 enerate potent antinociception more rapidly (maximal effect at 1h postinjection) but also lose their
41 the messenger RNA and protein levels, with a maximal effect at 2 hours (P < 0.05; n >/= 3).
42 ependent manner (IC50 = 0.5 mumol/L), with a maximal effect at 2.5 to 5.0 mumol/L.
43 ration of [14C]glucose into glycogen, with a maximal effect at 30 nmol/l leptin.
44 t a concentration as low as 10 nmol/l with a maximal effect at 5 micromol/l.
45  enhanced the activity of the enzyme, having maximal effect at 50 and 75 mM, respectively.
46      These effects were dose-dependent (half-maximal effect at 7 microM), saturable and specific (i.e
47 n by IAC was inhibited by SKF10047 with half-maximal effect at 7 microM.
48 onsumption in beta-HC9 cells (15-30%) with a maximal effect at 8 mmol/l for glucose and at 250 nmol/l
49                   With trypsin, CB2 showed a maximal effect at 8 mol of tOspB to 1 mol of mAb.
50 aC at actin/gelsolin ratios of <32:1, with a maximal effect at an actin/gelsolin ratio of 2:1.
51 e static quenching is saturable and has half-maximal effect at approximately 20 mM nucleoside or NTP,
52 a concentration-dependent manner with a half-maximal effect at approximately 5 ng/mL.
53                                      Dex had maximal effect at concentrations above 0.01 microM and w
54 enistein inhibited bone resorption with half maximal effects at 0.5 and 10 micromol/L and complete in
55 n the levels of COX-2 mRNA and protein, with maximal effects at 8-12 and 12-24 h, respectively.
56      Inhibition was dose-dependent with half-maximal effects at approximately 15-20 muM.
57 hanical allodynia from day 1 to day 10, with maximal effects at early time points.
58 on this measure, with OFQ/N(1-11) displaying maximal effects at higher (15-30 nmol) doses and OFQ/N(1
59 (15-30 nmol) doses and OFQ/N(1-7) displaying maximal effects at lower (0.15-1.5 nmol) doses.
60  pathology (e.g., dystrophic neurites), with maximal effects attained with approximately 1 mug/d dose
61 creasing unitary current amplitude, with CLR maximal effects being observed at 10-30 uM internal Ca(2
62 nt and was detectable at 0.3 nm insulin with maximal effect between 1 and 3 nm.
63  in a dose-dependent manner with an apparent maximal effect between 3 and 6 h after intravenous admin
64  progesterone produced approximately 1/2 the maximal effect but as little as 10 nM progesterone produ
65 euronal cultures with picomolar potency with maximal effects comparable to nerve growth factor.
66                            Further, the half-maximal effect concentration of C5a and the predicted do
67  an effect size greater than or equal to the maximal effect derived from linear modeling.
68 xone-reversible manner with good potency and maximal effect equivalent to that of the mu-opioid agoni
69 timulation, although this was lower than the maximal effect exhibited by the minimal mouse enhancer (
70 bitat intensity of 200 lux, for example this maximal effect (eyes always open versus always closed) w
71  glucagon receptor, Cpd 1 increased the half-maximal effect for glucagon stimulation of adenylyl cycl
72 ive, were elevated across the CF range, with maximal effects for CFs in the 10 kHz region.
73        The D50 (concentration producing half-maximal effect) for cocaine and U-50,488H was 10.3 and 1
74                ED50 (the dose producing half-maximal effect) for insulin's effect on leptin and FFA w
75 concentration required to achieve 90% of the maximal effect (IC(90)) of drug liking was 0.675 ng/mL.
76 )-1,1'-biphenyl] that increases the dopamine maximal effect in a dose-dependent manner in human and m
77 ere much more potent and/or had an increased maximal effect in inhibiting adenylyl cyclase and in act
78 on persisted above the MIC (TMIC), mediating maximal effect in the HFS-Mab, was used as the exposure
79 ecombinant GluN1/GluN3A receptors, with half-maximal effect in the physiologic pH range.
80 ions throughout most of the assessment, with maximal effects in summer, under low-nutrient conditions
81 te extension is severely limited after 24 h, maximal effect is reached at 36 h and recovery is only p
82 isease activity, the time required to attain maximal effect is unclear.
83  The Na+ effect was concentration-dependent (maximal effect, &lt;/=12.5 mM) and was specific for shear s
84 ted that TLK19780 acted very rapidly, with a maximal effect observed 2 min after addition to insulin-
85 is decrease was dose-dependent with the half-maximal effect observed at 0.5 microg/100 g of body weig
86 crease in [3H]thymidine incorporation with a maximal effect observed at 30 nm.
87 t relaxation of precontracted vessels with a maximal effect observed at 90 minutes.
88 peptides was dose and time dependent, with a maximal effect observed at 96 h (87 +/- 16% [mean +/- SE
89 ine CE cell N-cadherin mRNA levels, with the maximal effect observed between 10(-10) (1.47 +/- 0.06-f
90 ression in human PBMCs and monocytes, with a maximal effect observed when IL-10 was added from 20 h b
91 s-like positive nuclei in rat forebrain with maximal effects observed 2 h post-dose.
92  in high-intensity tail-flick latencies with maximal effects observed at a dose range of 0.75-3 nmol,
93 sed A(2A)AR in a time-dependent manner, with maximal effects observed by 1 day, and continued down-re
94 as measured by RNase protection assays, with maximal effects observed in early stages of HSC activati
95 osphotyrosine content of p38 MAP kinase with maximal effects observed within 5 min.
96 the tumor-determinant reactive T cells, with maximal effects obtained by combined anti-CD40 and anti-
97 entiation, but preclinical data suggest that maximal effects occur within 8-12 d.
98 e light response was about 80%, and the half-maximal effect occurred at 385 nm delta subunit.
99                                          The maximal effect occurred at 6 hours with 100 nmol/L Ang I
100 ried with the age of astrocyte cultures; the maximal effect occurred at approximately 2 weeks in vitr
101                                              Maximal effects occurred at a concentration of 3 mmol/L
102 un mRNA, in a time-dependent manner with the maximal effect occurring 2 h after the stimulation and a
103 centration-dependent manner with minimal and maximal effects occurring at 1 and 25 microg/ml, respect
104 sibly inhibited DeltaPsim fluctuations, with maximal effects occurring at 100 microM.
105 trations of ceramide as low as 5 microM with maximal effects occurring at a concentration of 15 micro
106 trast, there was no change in the potency or maximal effect of 2-MeSATP with the S317A mutant recepto
107  predicted these changes and showed that the maximal effect of addition of a sorbent to the dialysate
108  cells, CNP was five times more efficacious (maximal effect of CNP was 497% +/- 44% that of ANP) and
109           Insulin pretreatment increased the maximal effect of DAMGO, but did not change its EC(50) v
110              In these cells, the potency and maximal effect of delta-opioid receptor agonist (SNC80)-
111 dissociated profile by exhibiting 42% of the maximal effect of DEX in a mouse mammary tumor virus (MM
112 expression was 3.5 nM, exhibiting 87% of the maximal effect of dexamethasone (DEX).
113 ese responses were equal in magnitude to the maximal effect of estradiol, and they were inhibited by
114            Such stability suggests that near maximal effect of expiratory TGI could be obtained by ap
115             The simulation set limits to the maximal effect of eyes open all day versus eyes closed a
116                                          The maximal effect of insulin on tyrosine phosphorylation of
117 e, although the factors were equipotent, the maximal effect of LIF > CNTF.
118 tal SCs, with survival activity equaling the maximal effect of neuregulin, the major peptide SC survi
119 RE and the A/T-rich motif was required for a maximal effect of PLZF on a heterologous promoter and wa
120 in tissue oxygen delivery while awaiting the maximal effect of recombinant erythropoietin on bone mar
121 cited Ca(2+) elevations with a rank order of maximal effect of RTKA >/= SP > RTKC >/= RTKB.
122 sfer regions may result in a decrease in the maximal effect of signal transfer.
123 ntain biases dependent on the Hill-slope and maximal effect of single-drugs.
124                                              Maximal effect of the activator requires that the system
125                                          The maximal effect of the inhibitory compounds is enhanced w
126                                       A half-maximal effect of the muscarinic agonist carbachol was o
127 157F) had no effect on either the potency or maximal effect of.
128 Pase activity in a dose-related manner, with maximal effects of 29% increase over basal level seen at
129 n a concentration-dependent manner with half-maximal effects of approximately 1 nM.
130                                         Half-maximal effects of Ca(2+) were observed at approximately
131                                              Maximal effects of forskolin were observed at 10 micromo
132                                          The maximal effects of IAA and NPA are between 3.5 and 5 h A
133                                          The maximal effects of mucosal UDP on [3H]inositol phosphate
134                                  We find the maximal effects of non-substrate FAs on both huPGHSs occ
135                                              Maximal effects of these inactivating drugs occurred wit
136 RDLM314S) increased the potency, but not the maximal effect, of GABA potentiation by either propofol
137  system appears quite sensitive, with a half-maximal effect on a Pqrr reporter at 140 pM C8-AHL.
138 ably, PKM2-H391Y co-expressed cells showed a maximal effect on all the studied parameters.
139                    In endothelial cells, the maximal effect on angptl4 expression was achieved at 8 h
140                                The predicted maximal effect on cardiac output was observed at 1.2 min
141  increased free Ca(2+) concentration at half-maximal effect on channel activation, a reduced steepnes
142 iated with the binding of sugar might have a maximal effect on ChvE's interactions with its distinct
143 he last 2 estradiol pulses best captured the maximal effect on hippocampal CA1 spine density.
144 creases in permeability at 4 h, exerting its maximal effect on sucrose uptake at 24 h.
145                               To achieve its maximal effect on the LDL receptor, PCSK9 requires autop
146 logs were more potent and produced a greater maximal effect on the rate of [3H]spiperone dissociation
147 940-tolerant mice are capable of producing a maximal effect on the second messenger system.
148 es, in the majority (13/20), sites producing maximal effects on both variables coincided.
149  chemical shifts throughout the enzyme, with maximal effects on helix I (Val-15), beta-strand 1 of th
150 than that of B-cryptoxanthin or lycopene had maximal effects on ISI.
151 ced by changes in temperature will have near-maximal effects on pH-dependent conformational equilibri
152 ted a biphasic dose dependent response, with maximal effects on PKA noted at 10(-12)M peptide T.
153         We conclude that LXR is required for maximal effects on plaque CD68+ cell expression of CCR7
154                                       Nearly maximal effects on Rac activity were obtained with 10% s
155  the residual release is sufficient to exert maximal effects on the target NK-1 receptors.
156 rvilinear when the two drugs differ in their maximal effects or Hill slopes.
157 hanism to increase the potency, modulate the maximal effect, or alter the bias of ligands.
158                                          For maximal effect, (p)ppGpp interacts with the cofactor Dks
159 ative log molar concentration eliciting half-maximal effect [pD2] 9.2 +/- 0.03 and 8.9 +/- 0.03, resp
160  a concentration-dependent manner, with half-maximal effect produced at about 2 nM AODN concentration
161 ill coefficient of approximately two, a half-maximal effect reached by nearly 500 nm Ca(2+) , and Ca(
162                                              Maximal effects required approximately 200 microM phosph
163 lial electrical resistance for 3 hours (with maximal effect seen at 300 micromol/L H2O2), indicating
164 nce-mediated transcriptional responses, with maximal effects similar to those caused by interleukin-6
165                           The estimated half-maximal effect-site concentration of soticlestat was 5.5
166 bacteria required to trigger a response) and maximal effect size according to a logistic equation.
167 ed on the small sample size and the observed maximal effect size of 70%, the power of the study is at
168 s antagonize GLP-1 signaling, decreasing the maximal effect that GLP-1 can elicit on cAMP production
169  with a reversal t1/2 > 6 hours and close to maximal effects that remained for at least 5 hours after
170       We focused on the mutants that had the maximal effects to increase (in alpha4) or reduce (in de
171         At the lowest intensity, 3 lux, this maximal effect was +/- 28%, but it is only 1% at the hig
172   The concentration of UMP required for half-maximal effect was 2.5 microM.
173                                          The maximal effect was a 150% increase in compliance and a 4
174 izolid considerably, 25-fold on average, and maximal effect was achieved at an exposure equivalent to
175 oltage dependence of hERG1 inactivation, and maximal effect was achieved in channels containing three
176 tionship was apparent in the brain, and near-maximal effect was apparent with doses of 8 mg/kg.
177                               NMB had a half-maximal effect was at 0.4 nM and was 30-fold more potent
178 ased directly with pacing frequency, but the maximal effect was blunted with the T286A, consistent wi
179 ntially decreased the risk of death, and the maximal effect was not reached within the studied range.
180 A expression in a dose-dependent manner: the maximal effect was observed at a concentration of 10 ng/
181                                          The maximal effect was observed in children who received >75
182                                          The maximal effect was obtained when the cells were preincub
183                                         When maximal effect was seen, iNO was discontinued to compare
184                         Similar increases to maximal effect were observed after treatment with the ca
185                         Similar increases to maximal effect were observed after treatment with the ca
186                                              Maximal effects were observed at relatively longer time
187  into a beneficial effect on adiposity, with maximal effect when started at the earliest age and main
188 rmed phenotype in vitro all appeared to show maximal effect with 100 MOI AdMnSOD.
189 wer efficacy compounds showed an increase in maximal effect with a smaller shift in potency.
190 tical cell cycle regulators in order to have maximal effect with minimal input.
191  during 10 min of treatment, betaPEA induced maximal effects within 1 min.
192 reduced by forskolin treatment, in which the maximal effect yields an 80% reduction in AT1-R mRNA lev

 
Page Top