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1 frequency (<300 Hz) sinusoids that delivered maximally ~1% of the transcranial current to the auditor
5 evice-recorded AF burden at 1 year was 0% or maximally 5% of the time in 28/39 ablation patients (72%
9 ity in a period of 7 days at 10 nM, and half-maximally accelerated cell death combined with SN-38 at
10 with related viruses show that ZIKV MBEs are maximally accessible among mosquito-borne flaviviruses.
12 Existing methodologies focus on generating maximally accurate maps whereby minor states become disc
14 emonstrate that only toxic metalloporphyrins maximally activate expression of the Staphylococcus aure
15 orted concentration of cAMP required to half-maximally activate PKA, which measures in the 100-300 nM
16 ynergizes with primary activation signals to maximally activate platelets and render them prothrombot
17 y, we found that calcium levels necessary to maximally activate the thin filament mitigated the struc
18 d force observed when heart muscle cells are maximally activated by calcium is due to a change in thi
19 used to inhibit mouse liver PKC-lambda/zeta maximally activated by insulin or ceramide and a truncat
21 al, parietal, premotor, and prefrontal areas maximally activated by tactile stimulations presented at
22 nonhuman primate functional network that is maximally activated by tactile stimulations presented at
26 -AR activation and high [Ca(2+) ]i increased maximally activated tail IKs , negatively shifted the vo
27 the cerebral system for action monitoring is maximally activated when others' errors are coded as if
29 d shear stress, at arterial flow magnitudes, maximally activates NOTCH signaling, which upregulates G
32 nding to wherever inside cells the enzyme is maximally active and preclude minor populations present
34 active," being minimally active during W and maximally active during PS in negative correlation with
35 we found that many glutamatergic neurons are maximally active during REM sleep (REM-max), while the m
36 amatergic neurons were "W-max active," being maximally active during W and minimally active during PS
37 We found that all cholinergic neurons were maximally active during W and PS in positive correlation
41 endent cellulose production pathway that was maximally active when cultures were grown under reducing
42 es of intrinsic functional networks that are maximally active when resting relative to engaging in a
44 king group and reported here are intended to maximally address individuals, groups, and settings most
46 vity is maximized when the MR-ARFI MEGs were maximally aligned with the FUS propagation direction.
47 xidative stress and Th1 polarization and was maximally altered in patients with more severe mucosal i
48 ndogenous LECs and their natural environment maximally, and regenerates lenses with visual function.
49 eft inferior-parietal and cingulate regions, maximally around question offset, with high-gamma augmen
50 lation columns were found to be concentrated maximally around the pointed tips of each electrode.
52 2F domain directly binds the t-SNARE SNAP-25 maximally at 100 muM and with reduction at 0 muM Ca(2+),
53 ted that activating FcgammaRs were expressed maximally at 5 d post-infection (dpi), while the inhibit
55 PCLSs from naive Rgs5(-/-) mice contracted maximally at baseline independently of allergen challeng
56 w one to focus interventions on participants maximally at risk and at a stage prior to widespread syn
58 wo trajectories, but individuals with normal maximally attained FEV(1) had an increased risk of nonma
59 an accelerated decline of FEV(1) from normal maximally attained FEV(1) in early adulthood (normal max
60 ).Conclusions: COPD developed through normal maximally attained FEV(1) trajectory is associated with
61 y attained FEV(1) in early adulthood (normal maximally attained FEV(1) trajectory) but also through a
62 FEV(1) below normal in early adulthood (low maximally attained FEV(1) trajectory).Objectives: To tes
63 rticipants had developed COPD through normal maximally attained FEV(1) trajectory, 65 had developed C
64 rajectory, 65 had developed COPD through low maximally attained FEV(1) trajectory, and 1,026 did not
66 P = 0.01) compared with individuals with low maximally attained FEV(1).Conclusions: COPD developed th
67 EV1 could also lead to COPD in persons whose maximally attained FEV1 is less than population norms.
68 We show that host-seeking mosquitoes are maximally attracted to thermal stimuli approximating hos
71 nd inhibition of both kinases is required to maximally block the tumorigenic potential of pancreatic
73 xperiments demonstrated that bevacizumab was maximally bound to this anchoring molecule within 1 h, a
74 ttenuated dural-evoked Adelta-fiber neurons (maximally by 19%) and basal spontaneous activity (maxima
75 ally by 19%) and basal spontaneous activity (maximally by 33%) in the rat trigeminocervical complex,
79 approximately 50% from the in vivo level in maximally [Ca(2+) ]-activated cardiac trabecula accelera
80 r what information to share with patients to maximally capitalize on patient-centered realignment.
81 ion parameters are individually optimized to maximally characterize analytes from each new sample mat
86 y specialty (HHIs range from 0, representing maximally competitive markets, to 10,000 in markets serv
89 pendent component analysis jointly we sought maximally correlated, maximally interpretable latent dim
92 estral cnidarian forms, in Clytia the medusa maximally deploys the ancestral cnidarian-bilaterian tra
93 equal superposition of two eigenstates with maximally different energies; this state ideally reaches
94 tent diameter is the intentional fracture of maximally dilated stents, which can be accomplished usin
95 hat distinct sets of epigenomic features are maximally discriminative for different group-wise compar
96 wed as prototypical glasses in that they are maximally disordered while simultaneously being mechanic
97 f a glass since they are out of equilibrium, maximally disordered, hyperuniform, mechanically rigid w
98 Individual chains in the assembly approach a maximally-disordered, melt-like state which may be calle
101 olutions from multiple methods and selects a maximally diverse subset to produce an improved ensemble
102 fied a subpopulation of neurons that respond maximally during investigation and attack of male conspe
103 ltured human fibroblasts SAMHD1 is expressed maximally during quiescence preventing accumulation of d
104 ate potency 2-fold, increase the response to maximally effective concentration of agonist 4-fold, and
108 time of single channel currents activated by maximally effective concentrations of agonist but only h
116 aining approaches, with the goal of creating maximally efficient and effective approaches to training
117 ant technological goal is thus the design of maximally efficient engines working at the maximum possi
118 r, the data show that the brain adapts to be maximally efficient in the processing and control of two
120 as Claude Shannon's theoretical result that maximally efficient representational systems assign shor
121 ether GFR modulates PT endocytosis to enable maximally efficient uptake of filtered proteins in vivo.
123 In particular we find that selection can be maximally enhanced or suppressed at intermediate flow sp
124 evice in which charge and spin transport are maximally entangled and simultaneously controlled by an
125 tter, converting an |N> (x) |0> input into a maximally entangled N00N state (|N> (x) |0> + |0> (x) |N
126 the qubits' energy splittings, to produce a maximally entangled state of one (40)Ca(+) qubit and one
127 to enable the generation of a vast class of maximally entangled states suitable for measurements wit
130 lying BRCA network function holds promise to maximally exploit genome instability for hereditary and
131 ught to identify novel approaches that could maximally exploit the therapeutic index between tumor ce
132 oreal blood flow, suggesting that VCO2ML was maximally exploited in each experimental condition.
133 oxin and acquiring beneficial cargo, thereby maximally exploiting potential niche resources.Bacteria
134 occupy shallow burrows in sediments and are maximally exposed to the contaminants that accumulate wi
135 and, consistent with a causal effect, genes maximally expressed at each stage display selection for
138 pose that in quiescent cells where SAMHD1 is maximally expressed GTP binds to site 1 with very high a
142 y, a graph filtering technique called Planar Maximally Filtered Graph (PMFG) has been applied to many
143 at in a fully triangulated Miura-ori that is maximally floppy, adding constraints via the elimination
144 SAA1 forms stable soluble oligomers that are maximally folded at pH 4.3 with approximately 35% alpha-
146 This structure unexpectedly reveals that maximally four insulins can bind the 'T'-shaped IR dimer
149 2-coordinate buttress-type motifs, all with maximally Grotthus-ordered H-bond patterns that successf
151 nging", in which different populations spike maximally in alternating time bins, causing network outp
152 of administration (intravenous and oral) to maximally increase brain uptake of the avid and selectiv
154 tients to identify an oligomer sequence that maximally increased enzyme activity in all fibroblasts.
156 gions of greatest uncertainty, the algorithm maximally increases knowledge with each added measuremen
157 ysis parsed each participant's EEG data into maximally independent component (IC) source processes, w
159 in patients with severe asthma refractory to maximally indicated doses of inhaled corticosteroids.
160 (UVB and UVA from 300-400 nm) but instead is maximally induced by higher wavelengths ranging from 450
161 can be phosphorylated by SFKs [7], which is maximally induced by low shear stress in vitro and in vi
162 s study, we show that GITR ligand (GITRL) is maximally induced on APCs at day 2 post-lymphocytic chor
163 c irradiation in the AM, when p53 levels are maximally induced, is discussed in terms of the mutation
164 ritize small molecules that are predicted to maximally influence the expression of their target gene
165 encies at which the sensory cortices respond maximally, influenced the impact of FDP on perception, f
170 en them can be quantitatively explained by a maximally informative search strategy, where the searche
171 e implies that MID does not necessarily find maximally informative stimulus dimensions when spiking i
172 ted as combinatorial odor code, one which is maximally informative, with the most informative neurons
173 Compound 10g is a potent CETP inhibitor that maximally inhibited cholesteryl ester (CE) transfer acti
174 which is inhibited by stationary images, is maximally inhibited when the slope constant of the ampli
175 chanistic level can facilitate the design of maximally insulated systems featuring heterologously exp
179 ysis jointly we sought maximally correlated, maximally interpretable latent dimensions of brain conne
181 Inferior and anterior walls and septum were maximally involved, whereas inferolateral and right vent
182 T arrives at an identity: an experience is a maximally irreducible conceptual structure (MICS, a cons
184 y their stabilization energies, dipoles, and Maximally-Localized Wannier Function (MLWF) centers.
185 as a desensitization strategy, we sensitized maximally MHC-mismatched rhesus pairs with two sequentia
187 A bio-enabled, environmentally-friendly, and maximally mild layer-by-layer approach has been develope
189 ity and biphasic dose response curves of the maximally modified phosphoform are ruled out for basic s
190 treatment with OVA, nitrated OVA (nOVA), and maximally nitrated OVA (nOVAmax) were performed before m
191 mally repressive, fully nucleosomal, and the maximally non-repressive, nucleosome-free, configuration
194 nglish bilingual individuals participated in maximally parallel language-switching tasks in productio
195 for IscU at pH 8.0 show that its S state is maximally populated at 25 degrees C and that heating or
200 tudy also determined that all tested strains maximally produce, and extracellularly release, TpeL at
205 represents a soft-interaction analog of the maximally random jammed (MRJ) packings of hard particles
206 us to show the existence of relatively large maximally random jammed (MRJ) packings with exactly isos
209 y human macrophages with 10 nM RvD1 for 48 h maximally reduced the secretion of the proinflammatory c
216 aCD)-catalyzed lipid exchange can be used to maximally replace the sphingolipids and phospholipids in
217 fact: the receptor distribution is tuned to maximally represent information about the olfactory envi
218 onfigurations at steady state, including the maximally repressive, fully nucleosomal, and the maximal
220 ith our hypothesis, the right mid-insula was maximally responsive during the peak period of sympathet
221 anges in microvascular and cardiac functions maximally restrain the levels of cutaneous vasodilatatio
222 r, it remains unclear if these responses are maximally restrained by age-related changes in cutaneous
223 ding gene body and enhancer regions, and for maximally reversing abnormal promoter DNA hypermethylati
224 ntify single point mutations in the RNA that maximally sample suboptimal conformational space based o
225 t are normalized with respect to theoretical maximally segregated configurations, this framework prov
227 t deep-sea fish have a single visual pigment maximally sensitive at short wavelengths, approximately
228 specific allergen-presenting DC-RAs to half-maximally sensitized mice with ovalbumin or peanut aller
229 to identify gene expression weightings that maximally separate traits of interest, and found that re
230 to identify gene expression weightings that maximally separate traits of interest, and found that re
231 a VOI derived by discriminant analysis that maximally separated diagnostic groups (multiblock baryce
233 that representations of similar odorants are maximally separated, measured by the distance between th
236 ling is maximized by as few as five antigens maximally spaced on the surface of a 40-nm viral-like na
238 ard substrate however, the elastic moduli of maximally spread mEFs are greater than those of vim(-/-)
239 e actin filament resulted in a bond that was maximally stable at 8 piconewtons, with a mean lifetime
240 ncounter return periods of about 21 days for maximally steep waves, while less steep rogues occur abo
242 X-1-deficient, and PLN-deficient hearts, and maximally stimulated contractile and calcium kinetic par
245 centrations, characteristics associated with maximally suppressive, anti-inflammatory T(reg) cells.
246 nopusoocytes, we found that CMPI potentiated maximally the responses of (alpha4)3(beta2)2nAChR to 10m
247 This interest has arisen because it is a maximally thin membrane that, once perforated with atomi
248 he parahippocampal place area (PPA) responds maximally to environmental scenes during fMRI studies bu
249 previous studies, with most cells responding maximally to ITDs that correspond to the contralateral e
250 ls during flight and found that they respond maximally to visual movement corresponding to rotation a
252 ering in patients who have been stable on a "maximally tolerated beta-blocker dose," but this definit
253 ent a baseline exercise test while receiving maximally tolerated beta-blocker therapy that was contin
254 Low-sodium weight-reduction diet plus the maximally tolerated dosage of acetazolamide (up to 4 g/d
255 re randomly assigned to placebo-plus-diet or maximally tolerated dosage of acetazolamide-plus-diet.
257 , controlled, blinded trial to determine the maximally tolerated dose (MTD) of 3K3A-APC in ischemic s
258 Treatment according to an individualized maximally tolerated dose may achieve a comparable respon
259 ere enrolled (0.04, 0.15, 0.4 mg), because a maximally tolerated dose of 1.0 mg was identified in a p
260 any oncology drugs are administered at their maximally tolerated dose without the knowledge of their
262 a stable antihypertensive regimen including maximally tolerated doses of at least 3 drugs including
263 a stable antihypertensive regimen involving maximally tolerated doses of at least three drugs, inclu
264 gurgitation who remained symptomatic despite maximally tolerated doses of GDMT were randomized 1:1 to
265 despite treatment for at least 3 months with maximally tolerated doses of three drugs, from 12 second
270 severe (4+) secondary MR were randomized to maximally tolerated GDMT plus MitraClip or GDMT alone; 5
271 gurgitation who remained symptomatic despite maximally tolerated GDMT, regardless of prior CRT implan
272 gurgitation who remained symptomatic despite maximally tolerated guideline-directed medical therapy (
273 ith HF and severe MR who were symptomatic on maximally tolerated guideline-directed medical therapy (
274 s and improved quality of life compared with maximally tolerated guideline-directed medical therapy (
276 -C up to an additional 70% in the setting of maximally tolerated medical therapy and have the potenti
278 isk patients with LDL-C levels >=70 mg/dL on maximally tolerated oral therapies, including statins an
279 this 52-week trial, bempedoic acid added to maximally tolerated statin therapy did not lead to a hig
281 ezetimibe or PCSK9 monoclonal antibodies to maximally tolerated statin therapy may be cost effective
282 olocumab positions these drugs as add-ons to maximally tolerated statin therapy or for those with sta
284 0 mg per deciliter while they were receiving maximally tolerated statin therapy with or without addit
286 gh risk for cardiovascular disease receiving maximally tolerated statins, the addition of bempedoic a
287 oronary artery disease (CAD) patients taking maximally tolerated therapy and with LDL-C levels >200 m
288 matic HF and 3+ to 4+ secondary MR receiving maximally-tolerated medical therapy, edge-to-edge TMVr r
292 study was to determine whether the max-ICH (maximally treated ICH) Score provides improved and clini
293 onsist of three layers and those of cysts of maximally two, while spores were also more compacted tha
296 Our method is the simplest way to obtain maximally unbiased random sequences that are subject to
297 In E. coli, the napABC genes are transcribed maximally under anaerobic growth conditions in the prese