ライフサイエンスコーパス: maximum concentration

1 -ADPKD bile (849 +/- 144 pg/mL vs. 270 pg/mL maximum concentration).

2 ations required ( 10 uM) exceeded the plasma maximum concentration.

3 ); 24 of 27 samples had less than 50% of the maximum concentration.

4 of decreases related to a decrease in 8-hour maximum concentrations.

5 ies, showing rapid absorption (time to reach maximum concentration, 0.5 to 6.0 hours) and elimination

6 rom the beginning of its development up to a maximum concentration (1,789 mumol/Kg FW).

7 dose duvelisib was rapidly absorbed (time to maximum concentration, 1-2 hours), with a half-life of 5

8 57% of samples) and was found at the highest maximum concentration (100 ng/L), some of the higher lev

9 62-3949], -62% difference [45-72]; p<0.001), maximum concentrations (117 [91-159] vs 383 pg/mL [302-5

10 ime PAL activity began to increase, reaching maximum concentrations 15 h after inoculation.

11 Radish was grown in contaminated soil (maximum concentration 2.9 mg/kg dw) and control plot.

12 At the maximum concentration (50 ng/mL), IGF-I induced a 60-fol

13 the radical concentration back to a similar maximum concentration, a feature that is reproducible ov

14 TMZ was absorbed rapidly with maximum concentrations achieved in 0.90 hours, on averag

15 The maximum concentrations achieved were 3.02 0.07 g/L of BE

16 ne was observed compared to vancomycin, with maximum concentrations achieved within 48 hours.

17 g/m(3) in e-cigarette vapor exceed the ACGIH maximum concentrations allowable for workers of 370 mug/

18 orld Health Organization's guideline for the maximum concentration allowed in drinking water.

19 e range, with dose-proportional increases in maximum concentration, although the area under the curve

20 Model-derived maximum concentration and area under the concentration-t

21 Exposure (maximum concentration and area under the concentration-t

22 macokinetic analysis showed lower vorinostat maximum concentration and area under the curve (0 to 24

23 The ratios of the maximum concentration and area under the curve from time

24 Plasma pinitol concentrations, maximum concentration and AUC increased according to the

25 reased with escalating dose, but the time to maximum concentration and clearance did not differ acros

26 t), however, the cells traverse the crest of maximum concentration and migrate further before reversi

27 The median time to reach maximum concentration and terminal elimination half-life

28 med therapeutic concentration (ratios of the maximum concentration and the trough concentration) C(ma

29 Maximum concentration, time to maximum concentration, and area under the concentration/

30 were as follows for E2 area under the curve, maximum concentration, and concentration at 24 hours (C2

31 ea under the concentration time curve (AUC), maximum concentration, and concentration at end of dosin

32 tistically significant changes in clearance, maximum concentrations, and areas under the concentratio

33 e (AUC0-24h); 0.65 (90% CI, .55-.76) for the maximum concentration; and 0.51 (90% CI, .41-.63) for th

34 612 nm versus the reduced enzyme, reaches a maximum concentration approximately 30 microseconds afte

35 The two ferryl species reach a maximum concentration approximately 310 microseconds aft

36 initial rise of buprenorphine in plasma with maximum concentration around 24 hours, with an apparent

37 with recombinant ZP3R/sp56 (74% drop at the maximum concentrations assayed).

38 bed Pu extends >70 A from the surface with a maximum concentration at 10.5 A and a total coverage of

39 subjects consuming TJ with oil, reaching the maximum concentration at 24h.

40 ement of microplastic particles results in a maximum concentration at intermediate depths.

41 were detected for up to 24 h with respective maximum concentrations at 1 and 1.5 h.

42 EIAEDs significantly decreased the maximum concentration, AUC(0-12 hours), and predose trou

43 a concentration-dependent manner with a half-maximum concentration between 0.007 and 0.4 mg .

44 RWPs were detected during storm peaks with a maximum concentration between 6.4 and 18 mg/L, and conce

45 Mean maximum concentration (C(max)) and area under curve of B

46 Average maximum concentration (C(max)) and area under the curve

47 y-derived treatments, whereas differences in maximum concentration (C(max)) and time at maximum conce

48 The maximum concentration (C(max)) increased to 5060 ng/mL (

49 ion-time curve (AUC) of 167% (2.67-fold) and maximum concentration (C(max)) of 142% (2.42-fold).

50 n both normal and tumor-bearing mice, with a maximum concentration (C(max)) of 35-45 percentage injec

51 ea under the curve (AUC) predictions; 78% of maximum concentration (C(max)) predictions; and 70% of h

52 Doses predicted to produce equivalent maximum concentration (C(max)) values were selected (40

53 semaglutide with only 75% of the once-weekly maximum concentration (C(max)), a feature that could red

54 comes were trough concentration (C(trough)), maximum concentration (C(max)), and area under the conce

55 ) (area under the concentration-time curve), maximum concentration (C(max)), and minimum concentratio

56 ffected the area under the curve at 8 h, the maximum concentration (c(max)), or the time it took for

57 The maximum concentrations (C(max)) of ara-G occurred at or

58 ime curve from 0 to 168 h (AUC(0-168 h)) and maximum concentration [C(max)] of cagrilintide and semag

59 The maximum concentration Cmax and area under the concentrat

60 f 0.31 and appeared to influence RIF AUC and maximum concentration (Cmax) at a dose of 20 mg/kg, desp

61 The mean maximum concentration (Cmax) at a reasonably well-tolera

62 ion in rats resulted in 60-fold reduction in maximum concentration (Cmax) compared with cota immediat

63 litaxel levels greater than 0.05 mumol/L and maximum concentration (Cmax) of paclitaxel.

64 g per day, the median (range) plasma arsenic maximum concentration (Cmax) was 0.28 microM (0.11-0.37

65 DTG maximum concentration (Cmax) was significantly higher in

66 inimum steady-state concentration (Cmin) and maximum concentration (Cmax) were 0.78+/-0.46 microg/ml

67 r the concentration-time curve (AUC) and the maximum concentration (Cmax) were calculated for TAF and

68 der the curve 0 to 24 hours (AUC(0-24h)) and maximum concentration (Cmax) were calculated.

69 ns, there was no significant accumulation in maximum concentration (Cmax), and the intersubject varia

70 - to 24-hour area under the curve (AUC0-24), maximum concentration (Cmax), AUC0-24/MIC, Cmax/MIC, and

71 mary outcomes were total exposure (AUC0-24), maximum concentration (Cmax), CSF concentration, and gra

72 Antibody serum half-life (and maximum concentration [Cmax]) generally increased betwee

73 concentration, AUC extrapolated to infinity, maximum concentration [Cmax], and time to Cmax) were obs

74 Due to insufficient data, criteria maximum concentrations (CMCs) of only seven transition m

75 and both the area under the curve (AUC) and maximum concentration++ (Cmx) of total topotecan in plas

76 cleaning, and occupancy activities, reaching maximum concentrations during these activities of 130, 1

77 ener detected in most of the samples, with a maximum concentration exceeding 800 ng/g.

78 ic trapping concentrator, we could achieve a maximum concentration factor of approximately 800 for DN

79 sbuvir studies, the area under the curve and maximum concentration for sofosbuvir and GS-331007 in ad

80 ozone pollution days (with 2-day average 8-h maximum concentrations >=100 ug/m3 vs. < 70 ug/m3) range

81 nophen concentration (< or = 30 mins) with a maximum concentration (> 12 mg/L) to define "normal" emp

82 Geoside reach a maximum concentration in berry skins of Baco blanc at ve

83 The PK parameters (maximum concentration in plasma and area under the curve

84 les (median 44 [IQR 30-58] vs 69 [56-87]% of maximum concentration in standard curve; p=0.043; n=8 an

85 e released catecholamines, with an estimated maximum concentration in the cell culture volume of ~52

86 nd continuous data, i.e., the Fe minimum and maximum concentration in the microstructures, are used a

87 l was enhanced in inoculated samples whereby maximum concentrations in inoculated and cell-free sampl

88 9-CA-ADIN was found at maximum concentrations in WWTP effluent and rivers up to

89 Maximum concentration increases with increasing number o

90 The maximum concentration level of delivered doxorubicin exc

91 enidate was associated with a longer time to maximum concentration, longer time to maximum CNS dopami

92 The maximum concentration (mug/g) of the individual phenolic

93 (annual or warm season average of daily 8-h maximum concentrations) O(3) exposure with all-cause and

94 r to those reported in other countries, with maximum concentrations observed in fish and fishery prod

95 llowed a trend similar to that of AOXs, with maximum concentrations observed in the final treated wat

96 ns show fast elimination and reveal that the maximum concentration obtained in the blood after i.v. a

97 The maximum concentrations obtained were 700.94 mg CE/100 g

98 ons within leachate following planting, with maximum concentrations occurring 4 weeks post-planting (

99 .8 mug m(-3), respectively, were found, with maximum concentrations occurring at 2 pm LT, 150-200 km

100 detected mycotoxin in water samples, with a maximum concentration of 0.48+/-0.05ngL(-1) followed by

101 against the presence of copper ions up to a maximum concentration of 0.80 muM (equivalent to 50 ppb)

102 phenolic content (500 mg/kg oil), reaching a maximum concentration of 1.63 muM.

103 G1 and G2 in 3% and 14% of the samples at a maximum concentration of 1.9 and 6.8 mug kg(-1) respecti

104 ptake of [18F]FACBC in the tumor exhibited a maximum concentration of 146 nCi/mL at 35 min after inje

105 e channel with nominal volume of 15.2 muL, a maximum concentration of 200 mM ammonium acetate flowing

106 d as 78.06%, TRP as 81.92% and TAC as 84% on maximum concentration of 200 ug/mL.

107 ransient hydrogen (H2 ) formation reaching a maximum concentration of 205 +/- 13 ppmv was observed in

108 ve the maximum allowed for sorbic acid and a maximum concentration of 2105.36+/-178.60mgkg(-1).

109 sed more than 40 times during storms, with a maximum concentration of 2760 ng/L for E(15)additives, 8

110 astics were found in all 107 samples, with a maximum concentration of 32 particles/m(3) and a median

111 ion model was significant, and we obtained a maximum concentration of 53.4% at pH 7.56 and temperatur

112 ted for 75% of the SigmaPFAS profile, with a maximum concentration of 6800 mug/kg wet weight (ww).

113 ake flasks as suspension cultures, achieving maximum concentration of 7 x 10(5) cells/mL while keepin

114 nced using the Maillard reaction, reaching a maximum concentration of 71.8 g/L which represents a 42.

115 ied in all WWTP effluent grab samples with a maximum concentration of 73.4 ng/L, while the lowest con

116 national weighted mean of 32.7 mug/kg and a maximum concentration of 857 mug/kg, and exceeded the hu

117 as decreased, with a reduction in AUCtau and maximum concentration of about 30%.

118 A simple theory predicts that the maximum concentration of an analyte ion preconcentrated

119 Lower background [DEA] will limit the maximum concentration of analyte acids that can be deter

120 h a half-life of approximately 9 hours and a maximum concentration of approximately 4 hours.

121 ed the same course of increase and reached a maximum concentration of around 20 mug/g dry matter.

122 same as the strategy, S(MaxR*, that leads to maximum concentration of available nutrient in soil pore

123 The cytotoxicity of the maximum concentration of BNPs and free BAR used in in vi

124 of lipid matrix postponed and decreased the maximum concentration of both oxidation parameters.

125 The geometric mean maximum concentration of CBDA of 72.7 ng/mL was observed

126 without 0.05% acetate were the same, but the maximum concentration of cells was fourfold higher with

127 We calculated that the maximum concentration of CP and CL after intramammary tr

128 The maximum concentration of DBDPE (10,000 pg/m(3)) in outdo

129 The maximum concentration of DEX in nonvitrectomized versus

130 a 1:1:1 molar ratio of RTV, ATV and LPV, the maximum concentration of each drug was only one third of

131 nd range of the area under the curve and the maximum concentration of felodipine were significantly (

132 'high concentration barrier', describing the maximum concentration of fluorescent species tolerable f

133 These conditions resulted in a maximum concentration of fragments between 38 and 150 nt

134 The maximum concentration of free active sites in the C8-SCX

135 ion rate of ionic Ag(+) from the NPs and the maximum concentration of free Ag(+) released from the NP

136 The maximum concentration of HIV-1 RNA detected was 8100 cop

137 Furthermore, the maximum concentration of HT is reached between the fourt

138 The maximum concentration of ionic Ag(+) released from these

139 t and vine vigour affected the timing of the maximum concentration of norisoprenoid precursors and th

140 surfaces containing approximately 50% of the maximum concentration of oligonucleotides.

141 Mean maximum concentration of omecamtiv mecarbil at 12 weeks

142 We assessed the maximum concentration of omecamtiv mecarbil in plasma (p

143 Maximum concentration of pazopanib in plasma during cycl

144 While the maximum concentration of plasma EA after PJSP consumptio

145 bsorbance measurements yields , that is, the maximum concentration of SWNTs that can exist in the iso

146 With this method, we show that the maximum concentration of the available liposomal drug in

147 r ring-chain buffering occurs as well as the maximum concentration of the buffered molecule.

148 There was no relationship between dose, maximum concentration of the drug (C(max)), or area unde

149 a half-life of 20 to 22 days and provided a maximum concentration of the drug in excess of levels th

150 hanced eggs (produced by feeding hens at the maximum concentration of vitamin D3 or serum 25-hydroxyv

151 d that NI-TeDB-DiPhOBz and NI-BDE-209, up to maximum concentrations of 1.9 and 9 muM, respectively, c

152 e and carbamazepine diol-were detected, with maximum concentrations of 150.67, 601.95, and 89.18 ng/g

153 dehyde was not detected in food samples, the maximum concentrations of 24 and 95 ug kg(-1) were found

154 rapid production of hydrogen peroxide, with maximum concentrations of 3.85 muM.

155 ane sulfonamido diethanol (FBSEE diol), with maximum concentrations of 482 mug/L, 141 mug/L, and 83.5

156 (PFHxA) was the primary PFCA produced, with maximum concentrations of 57.4 +/- 6.5, 9.0 +/- 1.2, and

157 Initial and maximum concentrations of beta-carotene in serum and mil

158 assigned 1-week and 7-week averages of daily maximum concentrations of carbon monoxide, nitrogen diox

159 The autotrophic growth rates and maximum concentrations of cells were significantly lower

160 edium greatly increased the growth rates and maximum concentrations of cells.

161 icity at 222 nm decreases in the presence of maximum concentrations of denaturants in the order TFA >

162 While in tomato and potato samples, the maximum concentrations of ETU residues were reached on t

163 an be loaded onto class II-positive cells at maximum concentrations of exogenous peptide.

164 The maximum concentrations of galaxolide (HHCB) (447 ng g(-1

165 nd concentrations were similar among months; maximum concentrations of herbicides, insecticides, and

166 The maximum concentrations of lignans, total phenolics, flav

167 The maximum concentrations of LMW-PPs corresponded to the fl

168 Maximum concentrations of particles within 0.3 to 10 mum

169 Maximum concentrations of particles within 10-420 nm, ac

170 the specific sites where NK cells would face maximum concentrations of secreted perforin.

171 Maximum concentrations of studied compounds were detecte

172 e pharmacokinetics (area under the curve and maximum concentration) of lapatinib, capecitabine and it

173 MBs reached maximum concentration on day 5 of refeeding.

174 Capsaicinoids reached the maximum concentration on the 30th days post-anthesis (dp

175 Tumor uptake (maximum concentration or area under the concentration ve

176 ncluding area under the curve (P = .019) and maximum concentration (P = .006).

177 tacrolimus, for area under the curve (AUC), maximum concentration postdose (Cmax), minimum concentra

178 dosing regimens, the EDP-938 median time to maximum concentration ranged from 4 to 5 hours, and the

179 potassium concentrations up to cycle 3 with maximum concentrations reaching up to 5400, 397, and 233

180 t by comparing their migration values to the maximum concentration recommended by Cramer, e.g., ethyl

181 native systems had similar median and higher maximum concentrations, reflecting a wider range of syst

182 6+/-4 microm, and ADO: 37.2+/-4.1 microm, at maximum concentrations, respectively).

183 ea Chl-a depicts a distinct seasonality with maximum concentrations seen during the winter time (attr

184 nephrine, prostaglandin E1, and forskolin at maximum concentrations stimulated phosphorylation of the

185 Mean values of time to the maximum concentration (T(max)) were not significantly di

186 n maximum concentration (C(max)) and time at maximum concentration (T(max)) were observed; for exampl

187 took for plasma total (+)-catechin to reach maximum concentration (t(max)).

188 d concentration (C(max)/dose), time to reach maximum concentration (t(max), area under the blood conc

189 ) cells at concentrations up to 500 muM (the maximum concentration tested).

190 taining up to 20 mol % peptide, which is the maximum concentration tested, formed gel phases with mel

191 ture data and compared with estimates of the maximum concentration that can be tolerated in steel pro

192 sed as eluent for this purpose but generally maximum concentrations that can be tolerated are relativ

193 Moreover, maximum concentrations that leached from enameled glass

194 ms through photoinduced CS, accumulates to a maximum concentration, then dies away through CR.

195 Maximum concentration, time to maximum concentration, an

196 The time required to attain maximum concentration (Tmax) in CSF was less upon intran

197 nimum concentration postdose (Cmin), time to maximum concentration (Tmax).

198 ndoor air concentrations were similar to the maximum concentrations under natural conditions, and (d)

199 under the concentration-time curve (tau) and maximum concentration values for sofosbuvir, ledipasvir,

200 yl- (both class III toxicity) were above the maximum concentration values for three samples that were

201 ration time curve from days 0-210 and plasma maximum concentration values were slightly higher than t

202 The maximum concentration was 6 ng/mL.

203 ations increased rapidly, and median time to maximum concentration was 84.1 days (IQR 56.1-112.0) for

204 The maximum concentration was reached at 3 min followed by a

205 InO median maximum concentrations were comparable to simulated adul

206 , where safety data are reassuring, although maximum concentrations were higher in children weighing

207 Temporal changes in the site-wide maximum concentrations were used to estimate source atte

208 Median and maximum concentrations were, respectively, 1414 mg kg(-

209 ed cyclosporine area under the curve and the maximum concentration with GFJ (P < or = 0.007), but not

210 The maximum concentration within a typical one-chamber ant n

211 Ciraparantag reaches maximum concentration within minutes after IV administra