ライフサイエンスコーパス: maximum response

1 ween 1.5 and 3 pi radians at the location of maximum response.

2 important component of treatment to achieve maximum response.

3 wo of which are ongoing and have not reached maximum response.

4 units exhibited a steeper slope and a higher maximum response.

5 cularly sensitivity to GABA blockade for the maximum response.

6 tion of acetylcholine that produces half the maximum response.

7 tegorized into four classes based upon their maximum responses.

8 n-response curves with reduced but plateaued maximum responses.

9 dant manner (effector concentration for half-maximum response=1.2 mM+/-0.7).

10 ce of Ca2+, phosphatidylserine, and diolein (maximum response, 360 +/- 4% versus 342 +/- 9% of contro

11 ty = 5.7 microg/mL), and 58 (AC(50) = 38 nM, maximum response = 82%; solubility = 51.2 microg/mL).

12 bility = 7.3 microg/mL), 56 (AC(50) = 99 nM, maximum response = 84%; solubility = 5.7 microg/mL), and

13 probes of PKM2 including 55 (AC(50) = 43 nM, maximum response = 84%; solubility = 7.3 microg/mL), 56

14 macologic properties, specifically increased maximum response achievable and area under the curve, an

15 The mean maximum response after 4 mg/kg MK-801 was 13+/-2%.

16 esponse (I(1/2) ), Hill coefficient (n), and maximum response amplitude (R(max) ).

17 haelis-Menten equation to derive R(max), the maximum response amplitude, and sigma, the contrast nece

18 r-cell response and a surprising decrease in maximum response amplitude, both mediated by a change in

19 stitutions at Tyr217 substantially decreased maximum response and increased the EC50 for carbachol, d

20 Cone R(max) (maximum response) and cone S (sensitivity) parameters we

21 transduction to obtain values for log Rmax (maximum response) and log S (sensitivity).

22 (50) (the concentration that produces a half-maximum response), and the Hill coefficient (the maximum

23 .41 at 0 minutes, 0.37 at 1 minute, 0.42 for maximum response, and 0.39 for the area under the curve

24 gh expression of TRH receptor alone produces maximum responses approximately 48 h after injection, co

25 < 0.01; DNA, 28.4% increase, p < 0.001; HP, maximum response at 0.5 h, 50% increase, p < 0.001).

26 old increase in pro-TRH biosynthesis, with a maximum response at 10 nm.

27 ng in a concentration-dependent manner, with maximum response at 20 to 25 min.

28 nse was dose-dependent (EC50 = 25 nM) with a maximum response at 300 nM and a minimal observable resp

29 When comparing the maximum response at any L-DOPA dose to placebo, high eff

30 sensor response to NO reduction indicated a maximum response at pH 3.

31 The prepared enzyme electrodes exhibited maximum response at pH 7.0 and 45 degrees C +0.35 V and

32 mulation changed over the cycle, with larger maximum responses at both proestrus and estrus relative

33 ll changes in the ocean's O(2) content, with maximum responses at suboxic concentrations where anaero

34 lclozapine displayed substantially increased maximum responses at the Y106A and W101A mutants, slight

35 employed to optimize the conditions for the maximum response based on 54 different experiments.

36 hich choline is actually a full agonist, its maximum response being limited only by channel block.

37 NKCC2A-/- compared with wild-type mice, with maximum responses being significantly diminished.

38 Therefore, traditional features depending on maximum response change will cause confusion during furt

39 It exhibited a maximum response current to histamine at applied potenti

40 chemotherapy is at least 4-6 months or until maximum response, depending on toxicity and in the absen

41 motherapy is at least 4 to 6 months or until maximum response, depending on toxicity and in the absen

42 The receptor's maximum response depends on the difference in agonist bi

43 headings approximately perpendicular to the maximum response direction.

44 concentration required to produce 50% of the maximum response [EC(50)], 0.52+/-0.07 micromol/L) and e

45 y the empirical CRC parameters efficacy (the maximum response), EC(50) (the concentration that produc

46 a non-competitive mechanism that reduced the maximum response elicited by GABA.

47 compound model also explain why the reduced maximum response elicited by some partial agonists can b

48 ulatory effect of ACh was 0.15 microM with a maximum response equal to 67% of that obtained by a maxi

49 t bind to receptors but produce only a small maximum response even at concentrations where all recept

50 ric 5-HT3ARs (64 +/- 7% and 80 +/- 4% of the maximum response evoked by the endogenous orthosteric ag

51 intensity function types and their slope and maximum responses, for units with characteristic frequen

52 ET-1 in all (n = 12) C-units, with mean and maximum response frequencies of 0.08 +/- 0.02 and 1.5 +/

53 ET-1 was 3.16 +/- 0.31 min, and the mean and maximum response frequency were 2.02 +/- 0.48 impulses (

54 concentration of ligand that elicited 50% of maximum response in (86)Rb flux assays (K1/2), also refe

55 A maximum response is observed for 4.8-nm-thick PNS, with

56 ts in primary hepatocytes (20-fold), and the maximum response is obtained at a glucose concentration

57 A maximum response is produced at a dose of 4 micrograms/k

58 CB response showed a size-dependent shift in maximum response level from 2 microg/ml of 5 nm sized NP

59 he response and controlled response area and maximum response magnitude.

60 The video's green channel (maximum response near 540 nm) shows the color change due

61 a dose- and time-dependent manner, with the maximum response observed 30 min after MTII injection.

62 ude of the BRET signal was normalized to the maximum response obtained with 10 uM 2-(3,4-dichlorophen

63 ase of 3-4-fold in media VEGF levels, with a maximum response occurring at a concentration of 10 nM.

64 thin 6 h, with 1 mg/kg tamoxifen producing a maximum response of 15-20-fold.

65 T-based Ca(2+) flux assay, we found that the maximum response of alpha4beta2 receptors to agonist was

66 Moreover, a selective reduction in the maximum response of the high-affinity component was appa

67 The maximum response of the retinogeniculate synapses, conve

68 f the receptor to between 55 and 110% of the maximum response of the wild-type receptor to the agonis

69 the naked eye, and the time required for the maximum response of violacein (5 h) was less than that o

70 We found that experience increased maximum responses of putative excitatory neurons but had

71 atory neurons but had the opposite effect on maximum responses of putative inhibitory neurons, an obs

72 26.1% vs. 26.2% +/- 24.5%, P = 0.007; SPECT(maximum) response of 45% +/- 25.1% vs. 19% +/- 27.0%, P

73 Examination of the efficacies (maximum responses) of the various cytokines showed that

74 on the stimulus strength required for a half-maximum response, of the M-cone population was 38-fold l

75 Treatment was repeated every 28 days until maximum response or a maximum of 6 cycles.

76 ate and subsequently allowing the asymptotic maximum response probability to be a free parameter.

77 3 locations </= 15 dB, the fitted asymptotic maximum response probability was <80%, consistent with t

78 dB because of a reduction in the asymptotic maximum response probability.

79 ated a decrease in the apparent k(m) and the maximum response, R(max), suggesting a decrease in the n

80 aseline (non-drug) training, the time of the maximum response rate (peak time) for mature rats was ap

81 The maximum response rate (Rmax) and the reinforcement rate

82 mely the number of molecules per site n, the maximum response RM and the concentration at half satura

83 n the EC50 of carbachol and decreases in the maximum response (Rmax).

84 n at frequencies between 1 and 60 Hz, with a maximum response seen at 20 Hz.

85 h respect to the periphery, the time to half-maximum response (t1/2a) for arterial insulin was the sa

86 th 10-fold higher affinity and 3-fold higher maximum response than murine FXR-LBD.

87 The time to maximum response, the gallbladder ejection fraction, and

88 ression coefficient, R(2)=0.9912), while the maximum response time for each measurement was less than

89 initiation was individualized to begin after maximum response to AD as assessed by monthly digital re

90 tiation of RT individualized on the basis of maximum response to AD, achieves disease control rates c

91 in receptor-activating peptide, an increased maximum response to adenosine 5'-diphosphate and TxA2, a

92 pretreatment (10 microM, 48 hr) reduced the maximum response to agonist-stimulated [3H]inositol phos

93 The maximum response to alphabeta-MeATP was 36 +/- 23 % (ran

94 dependence also did not shift sensitivity or maximum response to baclofen in CA1 neurons.

95 nt gained 8-fold affinity and more than 250% maximum response to CDCA in vitro.

96 nd morphine activated GIRK currents, but the maximum response to DAMGO was greater than that of morph

97 The maximum response to glycine also appeared much reduced,

98 is defect corresponded to a reduction in the maximum response to insulin.

99 The maximum response to PbTx-1 was approximately two-fold gr

100 In untreated neurons, maximum responses to GABA and the apparent GABA EC50 inc

101 at, at pH 6.4 we observed a reduction in the maximum responses to the partial agonists B-alanine and

102 at, at pH 6.4 we observed a reduction in the maximum responses to the partial agonists beta-alanine a

103 periments at two latitudes demonstrates that maximum responses to warming are concentrated in late wi

104 ng that a decrease occurred in the BRI1 half-maximum response values.

105 min), and the concentration of FMLP for half-maximum response was 28.6 nM.

106 The mean maximum response was 39+/-4% at 20 Hz.

107 could be discontinued after six cycles if a maximum response was achieved.

108 lthough with graded dobutamine infusion, the maximum response was not different from that in controls

109 script, the screening time was very fast and maximum response was obtained up to 11-fold higher than

110 mm rostral to the calamus scriptorius (CS); maximum responses were elicited from a site 0.6 mm rostr

111 ive than wild-type control rods and that the maximum responses were much smaller in amplitude.

112 Maximum responses were observed when the radiation beam

113 The maximum response with 82% lysis of labeled target cells

114 d a substantial pH-dependent decrease in the maximum response with a pK(a) near 6.0.

115 At 20 and 25 mg/kg/day R-FB, we obtained the maximum response with up to 90% inhibition of total tumo

116 nt manner showing an age-related increase in maximum response without change in EC50 or slope value.