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1 100 mg MED), low (<50 mg MED), or none (0 mg MED).
2 cursor cells (GNP) and a MB cell line, PZp53(MED).
3 o Rituxan-induced apoptosis than Myc(ON)CD20(MED).
4 data through minimum entropy decomposition (MED).
5 mmatory profile (M1 [F4/80(low) Gr1(+) CD11b(med)]).
6 stent transmission mode of CCYV by B. tabaci MED.
7 They were deemed crossover to MED.
8 s no impact on disease severity in mice with MED.
9 mputer simulation to examine the accuracy of MED.
10 pes I-IV patients regardless of skin type or MED.
11 erythema was approximately 60% regardless of MED.
12 ioid doses below the risk threshold of 90 mg MED.
13 tion in rat cortex and showed highly potent (MED = 0.16 mg/kg) and efficacious antidepressant-like ac
18 he divergent GATA-type transcription factors MED-1 and MED-2 are encoded by an unlinked, redundant pa
19 he T-box factor gene tbx-35, a target of the MED-1 and MED-2 divergent GATA factors, was previously f
22 hIP) assays showed recruitment of AR, SRC-1, Med-1, transcription factor IIB (TFIIB), and polymerase
30 his Mediator complex subunit associates with Med 12, Med13, and cyclin C to form a submodule that is
31 D, 15.0%), escalating dose (from <3 to 20 mg MED, 13.7%), and de-escalating dose (from 20 to <3mg MED
32 esser quantities were fragments (ATL: 22.9%: MED: 14.7% PAC: 20.2%) and microbeads (4.8%; PAC only; t
33 mg MED, 27.3%), consistent high dose (150 mg MED, 15.0%), escalating dose (from <3 to 20 mg MED, 13.7
34 nt GATA-type transcription factors MED-1 and MED-2 are encoded by an unlinked, redundant pair of intr
35 actor gene tbx-35, a target of the MED-1 and MED-2 divergent GATA factors, was previously found to re
37 .2%; PAC: 3.4%), thermoplastics (ATL: 36.8%: MED: 20.7% PAC: 27.7%) and synthetic regenerated cellulo
38 by Trichopoulou et al (range: 0-9; N Engl J Med 2003;348:2599-608) exhibited the highest average yea
40 t in the primary report (Krystal et al., Nat Med, 2020), the current findings suggest that further tr
41 nd these cells are tumorigenic, whereas CD29(med)24(-/lo) and CD29(med)24(hi) cells have diminished t
42 origenic, whereas CD29(med)24(-/lo) and CD29(med)24(hi) cells have diminished tumorigenicity or are n
43 MED, 34.6%), consistent moderate dose (20 mg MED, 27.3%), consistent high dose (150 mg MED, 15.0%), e
44 of 65 medically managed transplant patients (MED), 30 patients supported with an LVAD, and 5 nonfaili
45 iagnosis emerged: consistent low dose (<3 mg MED, 34.6%), consistent moderate dose (20 mg MED, 27.3%)
46 The most abundant element is found to be Pb (med = 4.6 x 10(6) ng m(-3)), which is 40 times the secon
48 (27+/-17 and 27%, respectively; P<0.03) and MED (58+/-42 and 33%; P<0.05) versus CTRL (88+/-52 and 7
49 e of synthetic materials such as elastomers (MED: 61.2%; PAC: 3.4%), thermoplastics (ATL: 36.8%: MED:
50 r compared with younger patients assigned to MED (79% versus 60% for quartiles 4 and 1, respectively;
51 particles (n = 811) were fibres (ATL: 77.1% MED: 85.3% PAC: 64.8%) with blue and black being the dom
53 can result in multiple epiphyseal dysplasia (MED), a disease characterized by delayed and irregular b
54 he kinases, KinD, depends on the lipoprotein Med, a mutant of which has been known to cause a canniba
60 Enrichment using Droplet Pre-Amplification (MED-Amp) method, which combines single-molecule emulsifi
62 ssigned to medical therapy alone (MED) or to MED and coronary artery bypass graft (CABG) surgery in t
65 MYC oncogene, we predict interaction between MED and FBP1 might also have implications for cancer ini
66 on of the musculoskeletal phenotype of PSACH-MED and is directly relevant to the clinical management
67 largely mitigated by the outcomes of the PD MED and Levodopa in Early Parkinson's Disease (LEAP) stu
69 cells to selectively deplete subunits of the MED and TFIID complexes to dissect the contribution of e
72 i) metal-enhanced electrochemical detection (MED) and (ii) label-free surface plasmon resonance (SPR)
73 (STR), hippocampus (HC), medulla oblongata (MED) and anterior cingulate (ACNG) and five peripheral t
75 thresholds of two Scn8a mouse mutants, Scn8a(med) and Scn8a(med-jo), to flurothyl- and kainic acid (K
76 s guideline-based antidepressant medication (MED) and were randomly assigned to add-on therapy with c
77 N), 5 glioblastoma (GBM), 6 medulloblastoma (MED), and 5 nontumor brain (NT) control samples obtained
78 normal mammary stem cell markers, CD29(hi)24(med), and these cells are tumorigenic, whereas CD29(med)
79 that a homogeneous electron transfer between Med*+ and chalcone epoxides is facilitated by an electro
80 ormed in 65/602 patients (10.8%) assigned to MED, and 55/610 patients (9.0%) assigned to CABG receive
81 MP1, termed Alaskan, China 1, China 2, Med+, Med-, and NC, have been identified, and individuals can
85 a (PSACH) and multiple epiphyseal dysplasia (MED) are relatively common skeletal dysplasias belonging
90 affected by alanine substitutions in Mad and Med at a subset of basic residues within and flanking he
91 omonas) was first confirmed to be present in MED B. tabaci using Hiseq2500 and FISH technologies.
95 ls were enumerated by flow cytometry as CD45(med+) blood mononuclear cells expressing CD34, with addi
96 Here, we investigated the in vivo role of MED by generating a conditional null mice model in which
97 Finally, we report that overproduction of Med bypassed the dominant negative effect on transcripti
99 region for 2 hours 3 times a day), medicine (MED; carvedilol therapy at 12.5 mg PO BID), or control (
101 was previously observed in a murine model of MED caused by a Matn3 V194D mutation, some mutant protei
102 CD11b(high)]) and proresolving (Mres [F4/80(med) CD11b(low)]) phenotypes, without changing the numbe
106 days, confirming the M2 features of the MGL1(med)/CD11c(+) eATMPhi transcriptional profile and implic
108 ructure-associated MGL1(-)/CD11c(+) and MGL1(med)/CD11c(+) eATMPhis were identified after 8 weeks of
109 h the most immature subset (Oct4(hi)/CD44(hi/med)/CD24(-/+)) demonstrating chemoresistance, dormancy,
110 ating cells (TICs) that copurify with a CD24(med)CD49f(hi) population from premalignant ErbB2-express
114 ion is the thymus, where a few TCRgammadelta(med) cells can be induced to TCRgammadelta(hi) but only
116 ing igf2 signaling inhibited growth of PZp53(MED) cells, implicating igf2 as a potential clinical tar
117 and promoters and of MYC regulated ccnd2, 23 med complex components, and MYC regulated cell survival
128 be a novel mechanism whereby CD11c(hi)MHC II(med) DCs regulate the re-establishment of vascular quies
129 ar expansion, CD11c(hi)MHC class II (MHC II)(med) dendritic cells (DCs) accumulate later, and their s
134 ranscriptional coactivator complex Mediator (MED) facilitates transcription of nuclear hormone recept
139 nts the concept of metal-enhanced detection (MED) for the determination of DNA-DNA reactions and pres
142 both maternal and zygotic activities of the med genes act to specify endoderm, defects in endoderm s
144 he PADN group as compared to distance in the MED group (470 +/- 84 m vs. 399 +/- 116 m, respectively;
145 different across the spectrum of age in the MED group (53% versus 49% for quartiles 4 and 1, respect
148 group versus 149 +/- 73 dyn s cm(-5) in the MED group, mean between-group difference was 109 dyn s c
155 peaked during P10-14 and exhibited Siglec-F(med/high)CD11c(-/low) phenotypes, similar to allergic as
157 , we show that deletion or overproduction of Med impaired or enhanced, respectively, biofilm formatio
159 ssociated with lower mortality compared with MED in per-protocol and several time-dependent analyses
160 amenable to CABG were randomized to CABG or MED in the STICH trial (Surgical Treatment for Ischemic
161 diovascular hospitalization with CABG versus MED in younger compared with older patients (Pinteractio
162 V1.6 through a naturally occurring mutation (med) in mouse peritoneal macrophages inhibited podosome
163 icacy of CABG compared with medical therapy (MED) in patients with heart failure caused by ischemic c
167 i)/CD16(neg) [classical], CD14(+ or hi)/CD16(med) [intermediate], and CD14(neg)/CD16(hi) [nonclassica
171 uch disorder, multiple epiphyseal dysplasia (MED), is characterized by mild dwarfism and early-onset
172 us of brain slices from Scn8a mutant mice of med(J) type, in which there is greatly reduced spontaneo
175 wo Scn8a mouse mutants, Scn8a(med) and Scn8a(med-jo), to flurothyl- and kainic acid (KA)-induced seiz
177 lurothyl-induced seizures, Scn1a(+/-); Scn8a(med-jo/+) mice displayed thresholds that were comparable
180 ion in waist circumference was higher in the MED/LC group (-6.9 +/- 6.6 cm) than in the LF diet group
181 IPF volume had reduced twice as much in the MED/LC group compared with the LF group [-37 +/- 26.2 mL
182 sus -11.5% for the MED/LC; P<0.001), and the MED/LC group decreased reported carbohydrates intake (-3
184 e compared a Mediterranean/low-carbohydrate (MED/LC) diet plus 28 g walnuts/d with a calorically equa
185 c low-fat or Mediterranean/low-carbohydrate (MED/LC) diet+28 g walnuts/day with/without added moderat
186 ted fat intake (-21.0% versus -11.5% for the MED/LC; P<0.001), and the MED/LC group decreased reporte
188 ls isolated from the mediastinal lymph node (med-LN) of aged animals exhibited increased cardiotropis
189 the myocardium and mediastinal lymph nodes (med-LN) of infarcted mice, acquired a Treg phenotype wit
194 (high) CD16(low) CD35(low) CD10(low) S100A12(med-low) and, based on these markers, recovered in whole
196 s of LMP1, termed Alaskan, China 1, China 2, Med+, Med-, and NC, have been identified, and individual
197 s and peripheral myelinated axons from Scn8a(med/med) mice, which lack functional Na(V)1.6, no effect
198 tes with decreased enrichment of H3K27ac and MED (Mediator complex subunit)-1, and reduced recruitmen
202 We categorized dosages as large (>/=100 mg MED), moderate (50 to <100 mg MED), low (<50 mg MED), or
203 PC were enumerated by flow cytometry as CD45(med+) mononuclear cells expressing CD34 and subsets coex
205 on the cohort of 151 patients (STN-DBS n=67, MED n=84) resulted in a well-balanced sub-cohort includi
206 [ATL]: n = 30, four species; Mediterranean (MED): n = 56, two species; Pacific (PAC): n = 16, five s
207 dications to Enhance Depression Outcomes (CO-MED, n = 665), Establishing Moderators and Biosignatures
208 st this possibility, we recorded from GCs of med (Na(v)1.6-null) and wild-type mice during postnatal
209 Our data suggest the key target of the Psi/MED network in controlling developmentally regulated tis
214 vity in U87MG mouse xenografts, achieving an MED of 1.5 mg/kg, following weekly intravenous dosing.
215 ciaries with a prescription yielding a daily MED of more than 120 mg did not decline after adoption o
216 ibers; 5% had prescriptions yielding a daily MED of more than 120 mg in any calendar quarter; and 0.3
217 s yielding a daily morphine-equivalent dose (MED) of more than 120 mg, and treatment for nonfatal pre
218 utcome was daily morphine-equivalent dosage (MED) of opioids dispensed from 60 days before to up to 7
223 wer 5-year mortality than those who received MED only (25% vs 42%; hazard ratio, 0.50; 95% confidence
226 randomly assigned to medical therapy alone (MED) or to MED and coronary artery bypass graft (CABG) s
229 We hypothesize that the myopathy in PSACH-MED originates from an underlying tendon and ligament pa
230 northward and eastward future expansions of MED over both the Euro-Mediterranean and western North A
235 or-RNA polymerase II pre-initiation complex (Med-PIC) was assembled and analyzed by cryo-electron mic
238 ectories of opioid morphine equivalent dose (MED) prescribed during the 12-month period before the di
239 using multiple enzymes for sample digestion (MED), primarily an increase of sequence coverage, have b
241 INTERPRETATION: Results from SPYRAL HTN-OFF MED provide biological proof of principle for the blood-
245 was milder than that reported previously in med Purkinje neurons, which prompted us to look for diff
248 ession data from only 30 conditions and that MED results are robust to the existence of unknown occur
252 a metal-enhanced electrochemical detection (MED) sensor, which relied on the redox properties of a s
253 fates in Caenorhabditis, we have identified med sequence homologs in the related nematodes C. briggs
254 ily conserved multiprotein Mediator complex (MED) serves as an interface between DNA-bound transcript
255 y searching the genome for clusters of these MED sites, we have identified 19 candidate MED targets.
256 g a positive pilot trial, the SPYRAL HTN-OFF MED (SPYRAL Pivotal) trial was designed to assess the ef
257 ce of Med impaired and the overproduction of Med stimulated the transcription of two operons (sdp and
258 pathway, while reduction of Med15 levels, a MED subunit in the tail domain, suppressed the Nodal sig
260 osed that each TF interacts with a dedicated MED subunit to induce specific transcriptional responses
261 te GATA TF interface and suggest that binary MED subunit-TF partnerships are probably oversimplified
262 enes, implying shared or differential use of MED subunits by GATAs depending on the target gene.
264 10, reduction of Med12 and Med13 levels, two MED subunits in the regulatory domain, led to an enhance
266 Molecular structure analysis of purified Med-T and Med-T/TFIIH complexes by electron microscopy r
267 mplexes by electron microscopy revealed that Med-T corresponds to the mediator head module of higher
268 IIH-associated protein complex in T. brucei (Med-T) consisting of nine subunits whose amino acid sequ
269 lar structure analysis of purified Med-T and Med-T/TFIIH complexes by electron microscopy revealed th
271 and instantaneous firing rates were lower in med than in wild-type GCs, demonstrating that Na(v)1.6 c
272 the Annals of Internal Medicine (Ann Intern Med), the Annals of Surgery (Ann Surg), Obstetrics & Gyn
273 1.0% (mean, 8.8%) tumor cells are CD29(hi)24(med); these populations significantly increase to 16.5%
277 We demonstrate by in situ hybridization that med transcripts accumulate both in the EMS cell and in t
278 -) embryos made by mothers in which germline med transcripts have been abrogated by transgene cosuppr
279 with logistic regression analyses in the CO-MED trial using participants with complete data (N=431)
280 d no meaningful benefit (AUC=0.76) in the CO-MED trial were used to predict remission (AUC=0.80) and
285 tAlleles can be obtained from bioinformatics.med.utah.edu/~alun, which also has more information on i
286 o similar extents, the Alaskan, China 1, and Med+ variants had limited binding to the E3 ubiquitin li
290 heteroarenes mediated by a triarylimidazole (Med) was investigated by cyclic voltammetry (CV) and con
292 il in the deep Eastern Mediterranean Sea (E. Med.) water column and to minimize potential bias associ
293 hanisms that underpin the pathophysiology of MED we generated a murine model of epiphyseal dysplasia
294 search of electronic databases (Athens, Pub Med, Web of Science, Science Direct, AMED, CINAHL, Cochr
296 s how and why the geographic distribution of MED will change based on the latest-available climate pr
297 With these understandings, judicious use of MED will likely provide useful information about eukaryo
298 start with 70% of the minimal erythema dose (MED) with 20% increments at each treatment thereafter.
299 s were maintained on multi-electrode dishes (MED) with an 8x8 array of electrodes and examined for ph