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1 ns, potentially through mutagenic effects of meiotic crossover.
2 conversion in humans and its relationship to meiotic crossover.
3 Ly) plays a central role in the formation of meiotic crossovers.
4 s a change in the number and distribution of meiotic crossovers.
5 e genomic and epigenomic features underlying meiotic crossovers.
6 s mutations in one generation, and number of meiotic crossovers.
7 ther to a failure to resolve those DSBs into meiotic crossovers.
8 are euploid and exhibit near-normal rates of meiotic crossovers.
9 MEI-9 is required for the generation of most meiotic crossovers.
10 ave a less severe reduction in the number of meiotic crossovers.
11 is a major force governing the patterning of meiotic crossovers.
12 d duplication of 17p11.2 result from unequal meiotic crossovers.
13 that msh4 and zip1 affect the same subset of meiotic crossovers.
14 occur proximally than a comparable number of meiotic crossovers.
15 small chromosome 4, which normally never has meiotic crossovers [3].
16                                              Meiotic crossover activity in the genome proved high (17
17 ied in metazoa to affect the distribution of meiotic crossovers along the chromosome.
18  resolution) and find no correlation between meiotic crossover and de novo structural variants.
19 he basis of the underlying molecular rate of meiotic crossover and the coefficient of inbreeding caus
20 ed nicks being critical for the formation of meiotic crossovers and their distribution.
21 interacts with the MUS312 protein to produce meiotic crossovers, and that MUS312 has a MEI-9-independ
22 ed in cis with meiotic drive; suppression of meiotic crossovers; and copy-number instability, with a
23 ble roles for Holliday junction unwinding in meiotic crossover are discussed.
24                                              Meiotic crossovers are highly polarized along the chromo
25                           In mre-11 mutants, meiotic crossovers are not detected, and oocyte chromoso
26                In Schizosaccharomyces pombe, meiotic crossovers are produced primarily through a mech
27            The frequency and distribution of meiotic crossovers are tightly controlled; however, vari
28                                              Meiotic crossovers are typically evenly spaced, with eac
29                          This is because the meiotic crossovers between homologous chromatids are not
30                                              Meiotic crossovers can be formed through the interfering
31                                              Meiotic crossovers/chiasmata, that are required to ensur
32                                              Meiotic crossover (CO) recombination establishes physica
33                                              Meiotic crossover (CO) recombination facilitates evoluti
34 re, we review observations on two aspects of meiotic crossover control - crossover interference and r
35 on (NDJ), reflecting inherent differences in meiotic crossover control, yet the underlying basis of t
36 ination proteins is a fundamental feature of meiotic crossover control.
37 nation reaction is an essential component of meiotic crossover control.
38       Knowledge of the exact distribution of meiotic crossovers (COs) and gene conversions (GCs) is e
39                                              Meiotic crossovers (COs) are crucial for ensuring accura
40                                              Meiotic crossovers (COs) are needed to produce genetical
41                                              Meiotic crossovers (COs) are nonrandomly distributed alo
42                                              Meiotic crossovers (COs) are tightly regulated to ensure
43                                              Meiotic crossovers (COs) ensure proper chromosome segreg
44                                              Meiotic crossovers (COs) generate genetic diversity and
45                                              Meiotic crossovers (COs) have intriguing patterning prop
46                                              Meiotic crossovers (COs) have two important roles, shuff
47 del plant Arabidopsis thaliana indicate that meiotic crossovers (COs) occur through two genetic pathw
48                                              Meiotic crossovers (COs) play a critical role in generat
49  per homolog pair will be designated to form meiotic crossovers (COs), where reciprocal genetic excha
50 n to affect the frequency and positioning of meiotic crossovers (COs).
51 ue where it is required for normal levels of meiotic crossovers (COs).
52         Condensin is recruited near sites of meiotic crossover designation by pro-crossover factors b
53                                              Meiotic crossovers detected by pedigree analysis in the
54                   The relative influences of meiotic crossover distribution and population history on
55 the CDK consensus sites in REC-1 compromises meiotic crossover distribution in vivo.
56                  We further demonstrate that meiotic crossover distribution is markedly altered in ma
57 l further suggests that a subsequent unequal meiotic crossover event had generated an additional gene
58 s inverted on chromosome 14, which enables a meiotic crossover event that fuses the long arms of two
59                              In humans, most meiotic crossover events are clustered into short region
60 himpanzees, recombination hotspots, at which meiotic crossover events cluster, differ markedly in the
61  and studies involving fine-scale mapping of meiotic crossover events have led to a new generation of
62                                              Meiotic crossovers facilitate chromosome segregation and
63                                              Meiotic crossovers facilitate the segregation of homolog
64 t a significant alteration in the pattern of meiotic crossovers for specific genetic intervals.
65 of the Arabidopsis thaliana HEIP1 homolog in meiotic crossover formation and report its wide conserva
66           Mutations in hdm result in reduced meiotic crossover formation and sensitivity to the DNA-d
67 -1 (XND-1), known for its role in regulating meiotic crossover formation, is an early determinant of
68 at the proper removal of DMC1 is crucial for meiotic crossover formation.
69 but is an important factor in the control of meiotic crossover formation.
70                                              Meiotic crossover frequency varies within genomes, which
71                              A range for the meiotic crossover frequency was determined on the basis
72  To identify genetic variation that controls meiotic crossover frequency, we screened Arabidopsis acc
73  we have found mutations in highly conserved meiotic crossover genes that could support polyploid mei
74      To investigate the relationship between meiotic crossover hot spots and block-like linkage diseq
75 ods to characterize sperm conversions in two meiotic crossover hot spots in the major histocompatibil
76                          PRDM9 directs human meiotic crossover hot spots to intergenic sequence motif
77 ows that these areas correspond precisely to meiotic crossover hot spots.
78 t TAP2 molecules revealed a highly localized meiotic crossover hotspot approximately 1.2 kb long, unu
79                                              Meiotic crossover, i.e. the reciprocal exchange of chrom
80 e that an MER3-like function is required for meiotic crossover in plants and provide further support
81 ei (SPN) genotyping to directly measure male meiotic crossovers in 3136 pollen nuclei from 584 indivi
82 ey to reverse breeding is the suppression of meiotic crossovers in a hybrid plant to ensure the trans
83     We conclude that MEI-9 can generate some meiotic crossovers in an ERCC1-independent manner.
84  work has identified three pathways limiting meiotic crossovers in Arabidopsis thaliana that rely on
85 me size affects the rate and distribution of meiotic crossovers in budding yeast was tested.
86                                    Normally, meiotic crossovers in conjunction with sister-chromatid
87 view, we describe the pathway for generating meiotic crossovers in Drosophila melanogaster females an
88 ur finding that deletion of swi5(+) restored meiotic crossovers in eme1Delta cells.
89  been found to be responsible for nearly all meiotic crossovers in fission yeast.
90 s known about the fine-scale distribution of meiotic crossovers in human chromosomes.
91                                Generation of meiotic crossovers in many eukaryotes requires the elimi
92                                              Meiotic crossovers in outbred species, such as oil palm
93 t in vivo evidence that DNA breaks stimulate meiotic crossovers in plants.
94       Collectively, our results suggest that meiotic crossovers in potato are largely determined by t
95                                              Meiotic crossovers in the human genome cluster into high
96  to control and measure the distributions of meiotic crossovers in wild-type cells.
97           MEI-9 is also required to generate meiotic crossovers, in a function thought to be associat
98                                              Meiotic crossover interference is a one-dimensional spat
99 e previously proposed a "counting model" for meiotic crossover interference, in which double-strand b
100 shuffling of genetic material facilitated by meiotic crossovers is a critical driver of genetic varia
101                                The number of meiotic crossovers is tightly controlled and most depend
102                                        Human meiotic crossovers mainly cluster into narrow hot spots
103                  These mechanisms regulating meiotic crossovers may be conserved across species.
104  specificity between the mismatch repair and meiotic crossover MutS homologs in yeast is provided by
105 ome dosage compensation in somatic cells and meiotic crossover number and distribution in germ cells.
106 oteins reinforce and expand the model of two meiotic crossover pathways.
107 scopy to explore and mechanistically explain meiotic crossover pattering in Arabidopsis lines with fu
108                            We show here that meiotic crossover patterning is lost in Drosophila melan
109                                              Meiotic crossover patterning shows huge variation within
110                                              Meiotic crossover points were unevenly distributed acros
111                        In many cereal crops, meiotic crossovers predominantly occur toward the ends o
112                                              Meiotic crossovers provide an interesting example, defin
113                                              Meiotic crossovers rearrange existing genetic variation
114 nce and fertility rely on the stimulation of meiotic crossover recombination by potentially genotoxic
115 osome must pair with its homolog and undergo meiotic crossover recombination in order to segregate pr
116                                              Meiotic crossover recombination is essential for both ac
117                                              Meiotic crossover recombination rates impose a limit on
118 tromeres are also universally suppressed for meiotic crossover recombination, across eukaryotes.
119                              We propose that meiotic crossover regulation operates as a self-limiting
120 yt et al. now uncover a key role for Sgs1 in meiotic crossover regulation, which in turn reveals a jo
121                                              Meiotic crossovers result from homology-directed repair
122 t (Saccharomyces cerevisiae) have shown that meiotic crossovers result primarily from the biased reso
123                                              Meiotic crossovers shuffle parental genetic information,
124 ale genome-wide datasets we demonstrate that meiotic crossover sites display enriched genomic contact
125                             The formation of meiotic crossovers was previously posited to occur via t
126                   The vast majority (81%) of meiotic crossovers were mapped to less than 5 kb.
127                                              Meiotic crossovers were reduced in Drosophila rec, mei-2
128 hods have therefore been developed to detect meiotic crossovers within two different GC-rich minisate
129    Loss of Sgs1 also increases the number of meiotic crossovers without changing the frequency of gen

 
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