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1 igh potency and wash resistance (an index of membrane anchoring).
2 -Bbp1 complex is the central unit of the SPB membrane anchor.
3 rate that in C. crescentus, FzlC is one such membrane anchor.
4 naling by liberating EGFR ligands from their membrane anchor.
5 rane domain, an ectodomain, and a C-terminal membrane anchor.
6 hat provides a cytosolic domain and a plasma membrane anchor.
7 n carried out largely on atlastins lacking a membrane anchor.
8 e role of this substructure as a hydrophobic membrane anchor.
9 ytoplasmic tail of the Heart of glass (HEG1) membrane anchor.
10 as the expression level and geometry of the membrane anchor.
11 ows us to estimate the area density of these membrane anchors.
12 e with barriers for membrane exit due to the membrane anchors.
13 hile the nonspecific interactions are mainly membrane-anchored.
14 d the Sec17 apolar loop has functions beyond membrane anchoring.
15 f the gammaCA domain subunit composition and membrane anchoring.
16 ng; and (iii) mutation R252E, affecting nsP1 membrane anchoring.
17 single-point mutations of PhCCD1 to improve membrane anchoring.
19 ential for localization and interacting with membrane-anchored A-Kinase-Anchoring Proteins (AKAPs).
23 the C-terminal cytosolic tail of RHD3 has a membrane anchoring ability that is required for efficien
24 single-residue substitution that alters the membrane-anchoring ability of Ail significantly contribu
27 N-terminal helical segment having a role of membrane anchor, an unstructured C-terminal region that
29 ive amino acids N-terminal to the C-terminal membrane anchor and at a gamma-like site in the middle o
31 Photolysis releases the bioagent from its membrane anchor and thereby renders it biologically acti
32 s confirm that the combined functionality of membrane anchoring and microtubule tip affinity is in pr
33 residues resulted in significant loss of PLB membrane anchoring and mislocalization to the cytoplasm
36 terium tuberculosis, lack the canonical FtsZ-membrane anchors and Z-ring regulators described for E.
38 r the identification and characterization of membrane-anchored and extracellular proteins that bind h
41 ged residues, which is strictly required for membrane anchoring, and when transferred to the cytoplas
42 ifications are able to act as more than just membrane anchors, and dynamic S-acylation in particular
46 d II is polymerized, nascent polymers remain membrane-anchored at one end, and the other end becomes
49 utocatalysis severs the protein into a large membrane-anchored beta subunit that noncovalently associ
50 337-Gly340, Thr343, and Thr345) could act as membrane anchor, binding interface for a second rhodopsi
51 n from the membrane-anchored transducer, and membrane-anchored biotin displayed on the surface of a s
53 hic helix of the monomers not only acts as a membrane anchor but also generates significant positive
54 ocation channel as a weakly self-interacting membrane anchor but establishes a heteromeric TM-TM heli
55 ontain a beta barrel domain that serves as a membrane anchor, but the assembly and quality control of
56 FAT signalling whereas the dominant negative membrane-anchored C-terminal fragment (PC1-MAT) increase
58 on of Ca(2+) influx by the dominant negative membrane-anchored C-terminal tail fragment of PC1 elevat
59 The FtsZ GTPase domain is separated from its membrane-anchoring C-terminal conserved (CTC) peptide by
60 oluble forms of the protein lacking both the membrane-anchoring C-terminal tail and the intrinsically
61 gulation in Magnetospirillum gryphiswaldense Membrane-anchored CcfM localizes in a filamentous patter
67 tissue injury by physical separation of the membrane-anchored cofactor tissue factor (TF) from inact
68 ucleate actin filaments colocalize in plasma membrane-anchored complexes called nodes in the constric
70 euronal loss were significantly reduced when membrane-anchored CX3CL1 C-terminal fragment (CX3CL1-ct)
73 erminal calpain protease is regulated by the membrane-anchored DEK1 MEM, which is connected to the ca
75 most relevant avenues and accomplishments of membrane-anchored DNA nanostructures for investigating,
77 by a 'glycan', which is preassembled onto a membrane-anchored dolichol molecule embedded within the
80 uence located between its Bcl-2 homology and membrane anchor domains and blocks homo- and heteromeric
83 ith Bag1 then shifts hERG degradation to the membrane-anchored E3 ligase TRC8 and its E2-conjugating
84 VSV vectors (N4CT1-EBOVGP1), which expresses membrane-anchored EBOV GP from the first position in the
85 plant secretory system, KORRIGAN1 (KOR1), a membrane-anchored endo-beta-1,4-glucanase involved in ce
90 ver, more recent work has suggested that the membrane-anchored epithelial cell serine protease matrip
91 subtilis grows without FtsA or the putative membrane anchor EzrA and why bacteria lacking FtsA conta
93 and the membrane; in the active state, with membrane-anchored farnesyl and unrestrained HVR, the cat
95 in has a globular head that is attached to a membrane-anchored flexible stalk of approximately 80 res
98 esent evidence that type I myosin is the key membrane anchor for endocytic actin assembly factors in
100 ) are functionally important glycolipids and membrane anchors for cell wall lipoglycans in the Coryne
102 fluenza virus type 1 (rHPIV1) expressing the membrane-anchored form of EBOV glycoprotein GP, as an in
104 mor surveillance functions when expressed in membrane-anchored form on activated immune effector cell
105 f FtsZ regulators and establishes a role for membrane-anchored FtsZ in the regulation of cell wall hy
107 e show that WNT5A stimulates dimerization of membrane-anchored FZD4 CRDs and oligomerization of full-
109 in 2 to a GPR27V2 chimera in the presence of membrane-anchored G protein-coupled receptor kinase-2.
114 membranes, we redesigned it by introducing a membrane anchor group based on negatively charged sulfon
115 nditions in the absence of other activators, membrane-anchored GTP-Rab5A provides strong, virtually b
117 n of the human enzyme lacking its N-terminal membrane anchor has allowed for physical and biochemical
122 screening, these antibodies are expressed as membrane-anchored IgM (mIgM) in 293F indicator cells.
123 inct mechanisms: classic signaling using the membrane-anchored IL-6 receptor and trans-signaling usin
124 used to a glycosylphosphatidylinositol (GPI) membrane anchor, immobilizing it on the extracellular su
125 ns, two amphipathic helices, and an in-plane membrane anchor in IL-26, which are structural features
127 lts provide new evidence for the role of the membrane anchor in PrP-lipid interactions, highlighting
132 scopy, and determined distinct structures of membrane-anchored KRAS dimers in the active GTP- and ina
134 in vivo delivery of a corresponding soluble membrane anchored ligand, we generated lipidated analogs
136 which leads to multivalent interactions with membrane-anchored ligands and very high binding affiniti
147 LpoA structures helped explain how an outer membrane-anchored LpoA can either withdraw from or exten
150 thought to depend on the mobilization of the membrane-anchored matrix metalloproteinases MMP14 (MT1-M
151 elaxed lipid density; therefore this type of membrane anchor may assist in keeping the Z ring positio
152 e test the hypothesis that the length of the membrane anchor may impact the outcome by comparing sing
153 Although Fis1 is dispensable for fission, membrane-anchored Mdv1, Mff, or MiDs paired individually
155 te tethered to a genetically targeted-plasma membrane anchor (membrane anchored Photoswitchable Ortho
156 have attached mucus as they did not shed the membrane-anchored meprin beta into the luminal mucus.
157 ntegrin And Metalloprotease (ADAM) family of membrane-anchored metalloproteases are synthesized as pr
159 ial regulator of cell-cell interactions, the membrane-anchored metalloproteinase ADAM17, in endochond
160 lpha)-converting enzyme (TACE) are prominent membrane-anchored metalloproteinases that regulate the t
164 sults are consistent with a model in which a membrane anchored MinC/MinD complex is targeted to the Z
166 irectly to lipid bilayers and identified its membrane anchoring moiety, consisting of a hydrophobic l
167 We reason that the transport efficiency of membrane-anchored motors is reduced because of their sli
169 s (MMPs) are a family of secreted soluble or membrane-anchored multimodular peptidases regularly foun
170 ively, these findings indicate that MyoB are membrane-anchored myosin receptors that define a distinc
175 its role in the biosynthesis of lipid A, the membrane anchor of lipopolysaccharide (LPS), has not bee
176 ents of the bacteria, including lipid A, the membrane anchor of lipopolysaccharide, could affect any
179 The diffusivity, majorly influenced by the membrane anchor of the component, and the repulsed abili
181 eurofascin-186 enrichment in turn reinforces membrane anchoring of Ankyrin-G and subsequent recruitme
183 hai3 on cell membranes and that constitutive membrane anchoring of GIV in yeast cells or rapid membra
185 pecifically induce BPL cell apoptosis due to membrane anchoring of sTRAIL and simultaneous activation
187 CaaX motif (class B), which is important for membrane anchoring of the protein; the presence of such
189 ting the dynamics and thermodynamics of this membrane anchor on a POPC bilayer using all-atom, explic
192 sion of the K2 C terminus as an extension of membrane-anchored P-selectin glycoprotein ligand-1 (PSGL
194 ECAM) is a approximately 180-kDa multidomain membrane-anchored pan-peptidase inhibitor, which is clea
198 entirely dependent on CD4 anchoring, not on membrane anchoring per se, and required optimal Ab geome
199 ividing cells expand their PG layer by using membrane-anchored PG synthases, which are guided by dyna
200 genetically targeted-plasma membrane anchor (membrane anchored Photoswitchable Orthogonal Remotely Te
202 oblasts had not previously been screened for membrane anchored proteases that could contribute to cel
205 Semaphorin 7a is a glycophosphatidylinositol membrane-anchored protein that promotes attachment and s
206 esent genetic evidence that a putative inner membrane-anchored protein with a large periplasmic domai
207 ied in the cytoplasmic N-terminal end of the membrane-anchored protein YfgM of Escherichia coli.
213 are used as a zip code to guide a subset of membrane-anchored proteins through the secretory pathway
215 Adam10), a member of the ADAM family of cell membrane-anchored proteins, has been linked to the regul
217 e membrane-associated, involving a myriad of membrane-anchored proteins, proteomic efforts to better
226 d by the IL1RL1 gene, is expressed as both a membrane-anchored receptor (ST2L) activated by IL33 and
227 d sensitively on the binding constant of the membrane-anchored receptor and ligand proteins that medi
231 des in this network are myosins XI and their membrane-anchored receptors (MyoB) that, together, drive
233 ore dynamic than truncated forms lacking the membrane-anchoring region, despite sharing the same stea
236 ized by the fusion of ribbon precursors with membrane-anchored ribbons that also appear to fuse with
238 vaccine that encodes a prefusion stabilized, membrane-anchored SARS-CoV-2 full-length spike protein.
239 binding domain; or BNT162b2, which encodes a membrane-anchored SARS-CoV-2 full-length spike, stabiliz
240 Syntrophins are a family of proteins forming membrane-anchored scaffolds and serving as adaptors for
242 and refine the NMR measurements on the Htt17 membrane anchor segment of huntingtin that is of fundame
243 their hydrophobic N-terminal polymerization/membrane anchor segment with the major pilins but are mu
244 both the hydrophobic signal sequence and the membrane anchor sequence promoting translocation of the
247 emical analyses, matriptase, a member of the membrane-anchored serine protease family, is found to pl
251 Matriptase-2 (MT2), encoded by TMPRSS6, is a membrane-anchored serine protease that plays a key role
257 ur knowledge of non-proteolytic functions of membrane-anchored serine proteases and provides unexpect
258 biochemical observations regarding these two membrane-anchored serine proteases and their downstream
260 n, however, has focused on the potential for membrane-anchored serine proteases to regulate PAR activ
261 evidence for an interplay between PAR-2 and membrane-anchored serine proteases, which may co-conspir
263 e showed that BACE1 can effectively shed the membrane-anchored signaling molecule Jagged 1 (Jag1).Wea
264 on its own interferes with the zippering of membrane-anchored SNARE complexes midway through the zip
267 mino acid-induced cleavage of this synthetic membrane-anchored substrate occurs in a Deltatether stra
268 ydrogenase that lacks a typical cytochrome b membrane anchor subunit, which transfers electrons to th
269 ains unclear if R7BP serves exclusively as a membrane anchoring subunit or further modulates RGS prot
270 rt that RGS7 is selectively modulated by its membrane anchoring subunit R7BP, which sets the dynamic
271 eared to be secreted and Mmp2 appeared to be membrane-anchored, suggesting that protein localization
275 gand recognition by this enigmatic family of membrane-anchored TGF-beta family signaling regulators a
276 geted to the plasma membrane by a C-terminal membrane anchor that comprises a farnesyl-cysteine-methy
277 ChE is anchored at the TSC by a proline-rich membrane anchor, the small transmembrane protein anchor
280 e results indicate that being more than just membrane anchors, TM helices could play an important rol
281 rast, low pH did not affect the formation of membrane-anchored TNFR1-containing signaling complex (co
282 is of fundamental importance: it serves as a membrane anchor to control the localization of huntingti
284 K2-in which both protease recruitment to the membrane-anchored transcription factor and LOV domain op
285 t, which together produce translocation of a membrane-anchored transcription factor to the nucleus to
286 ity is read out via proteolytic release of a membrane-anchored transcription factor, and we temporall
287 iotin, did not displace the protein from the membrane-anchored transducer, and membrane-anchored biot
289 cated form of the Rieske protein lacking the membrane anchor (trunc-TtRp) to investigate redox-state-
294 omposed of cytosolic V1-sector and lysosomal membrane-anchored V0-sector, regulates lysosomal acidifi
295 le CX3CL1 isoform, suggesting that it is the membrane-anchored version of CX3CL1 that regulates micro
296 ht to determine the relative contribution on membrane-anchored versus soluble CX3CL1 in regulating th
298 ntly, structure and orientation of the Htt17 membrane anchor were determined using a combined solutio
300 scherichia coli interaction of FtsZ with its membrane anchors, ZipA and FtsA, as well as the spatial