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1 an increase in the unsaturation index in the membrane microdomain.
2 n that carotenoids play a role in organizing membrane microdomains.
3 ynamic changes in its localization in plasma membrane microdomains.
4 d that prestin localizes in cholesterol-rich membrane microdomains.
5 glutinin (HA), which is also found in plasma membrane microdomains.
6 rgeted to synapses and clustered in modified membrane microdomains.
7 lux by clustering NMDA receptors in modified membrane microdomains.
8 anize--they are not templated by preexisting membrane microdomains.
9 gered by changes in the lipid composition of membrane microdomains.
10 dt) is dependent upon the integrity of lipid membrane microdomains.
11 fts by redistributing cholesterol into these membrane microdomains.
12 singly to identify clustering of proteins in membrane microdomains.
13 in localizes a portion of Galpha(s) to these membrane microdomains.
14 hieved by receptor exclusion from lipid raft membrane microdomains.
15 ents are associated with detergent-resistant membrane microdomains.
16 hat N-myristoylated cystin fractionates with membrane microdomains.
17 at M. truncatula FLOT2 and FLOT4 localize to membrane microdomains.
18 via Ca(2+) activation of AC activity within membrane microdomains.
19 PKC-alpha within intact cholesterol-enriched membrane microdomains.
20 signaling events in these specialized plasma membrane microdomains.
21 y regulating trafficking to cholesterol-rich membrane microdomains.
22 ith phospholipase D2 (PLD2) in caveolin-rich membrane microdomains.
23 f proteins, including some connexins, within membrane microdomains.
24 ne potential site of action is in lipid raft membrane microdomains.
25 of the protein to reside in cholesterol-rich membrane microdomains.
26 perturb membrane structure by alteration of membrane microdomains.
27 marker protein that is enriched in caveolae membrane microdomains.
28 ngolipid stereochemistry in the formation of membrane microdomains.
29 plasma membranes, consistent with localized membrane microdomains.
30 ively transfer GSL to or from these putative membrane microdomains.
31 ral additional gamma-secretase substrates in membrane microdomains.
32 45, suggesting that they arise from distinct membrane microdomains.
33 erized as caveolin and flotillin-rich plasma membrane microdomains.
34 cells cluster signaling complexes in plasma membrane microdomains.
35 The levels of GM3 in the cell also affect membrane microdomains.
36 vivo with sphingolipid- and cholesterol-rich membrane microdomains.
37 roteins preferentially colocalize with fluid membrane microdomains.
38 nhances DAT localization in cholesterol rich membrane microdomains.
39 and phospholipase D2 (PLD2) in caveolin-rich membrane microdomains.
40 mbranes, suggesting budding from specialized membrane microdomains.
41 d VRCs for robust replication in PE-enriched membrane microdomains.
42 dt) is dependent upon the integrity of lipid membrane microdomains.
43 nhances DAT localization in cholesterol-rich membrane microdomains.
44 promotes proper docking of LPS in lipid raft membrane microdomains.
45 ng molecules at subcellular compartments and membrane microdomains.
46 ruitment and colocalization of RhoB to these membrane microdomains.
47 odifying insulin receptor translocation into membrane microdomains.
48 d PC7 promotes their association with plasma membrane microdomains.
49 orters that, nonetheless, remain confined to membrane microdomains.
50 rkers were recently developed to investigate membrane microdomains.
51 e clustering of MHC-II present in lipid raft membrane microdomains, a process that leads to MHC-II en
54 ronment, and role of this channel in sensory membrane microdomains, all of which helps to understand
55 rofile is reminiscent of detergent-insoluble membrane microdomains, although our approach is valuably
56 membranes exhibited numerous large abnormal membrane microdomains (aMMDs), which trap and inactivate
57 te the distribution of prestin within plasma membrane microdomains and affect prestin self-associatio
58 teins are spatially regulated between plasma membrane microdomains and between the plasma membrane an
59 -FRET, we revealed that AtHIR1 is present in membrane microdomains and co-localizes with the membrane
60 depletion microscopy the key roles played by membrane microdomains and cytoskeleton transient organiz
61 ds, leading to a reduced inclusion in plasma membrane microdomains and decreased uptake by caveolar e
62 f PP2A and PP2A regulatory enzymes in plasma membrane microdomains and identify a novel methylation-d
63 ls by pDCs involves CD81- and CD9-associated membrane microdomains and induces potent IFN-alpha produ
64 s an adaptor module that targets rPGRP-LC to membrane microdomains and interacts with the negative re
65 ncorporated into and localized within plasma membrane microdomains and proximal vesicles in T cells.
67 gle-particle tracking analysis revealed that membrane microdomains and the cytoskeleton, especially m
68 rological synapses, providing a link between membrane microdomains and the formation of polarized mem
69 Sphingolipids represent a major component of membrane microdomains, and ceramide-enriched microdomain
70 esterol and sphingolipid-enriched lipid raft membrane microdomains, and delivery of protein ligands t
71 cally associated with RPS2, are localized in membrane microdomains, and quantitatively contribute to
72 es are differentially regulated in different membrane microdomains, and the overall activity of this
73 there is increasing evidence to suggest that membrane microdomains, and their modulation, have an imp
77 ence that cholesterol- and sphingolipid-rich membrane microdomains are involved in regulating traffic
78 ther, these data demonstrate that structured membrane microdomains are necessary for ceramide-induced
79 used on lipid rafts and confirmed that these membrane microdomains are required for IL-6 and IGF-I si
80 elated proteins implicated in scaffolding of membrane microdomains, are rapidly recruited to the urop
82 recent work has highlighted sphingolipids in membrane microdomains as potential targets for inhibitio
83 y described Incs were localized to inclusion membrane microdomains, as evidenced by colocalization wi
84 DCA stimulated TGR5 redistribution to plasma membrane microdomains, as localized by immunogold electr
85 , CD4 and G protein were present in separate membrane microdomains, as shown by double-label immunoel
86 ObRa because of differential involvement of membrane microdomains, as shown by use of the clathrin i
87 r to involve a general reorganization of the membrane microdomains associated with virion assembly, b
89 herin is localized to a spatially restricted membrane microdomain at the apical inner segment recess
90 s well, by recruiting TCR/pMHCI complexes to membrane microdomains at a rate which depends on the aff
92 sses, such as protein sorting, organelle and membrane microdomain biogenesis, protein-protein interac
93 precursors show evidence of Par3-expressing membrane microdomains, but fail to develop normal apical
94 llular matrix proteins in specialized plasma membrane microdomains, but the effects of these interact
96 the extent of organization of proteins into membrane microdomains by analyzing the distribution of p
98 Astrocytes exhibit spatially-restricted near-membrane microdomain Ca(2+)transients in their fine proc
99 -1 (Cav-1), the major protein of specialized membrane microdomains called caveolae, which functions i
100 Exosome uptake depends on cholesterol-rich membrane microdomains called lipid rafts, and can be blo
102 ocalization with these receptors on the same membrane microdomain can also recruit thrombin to activa
104 estigate the role of cholesterol-rich plasma membrane microdomains (caveolae and lipid rafts) in GH s
106 of PrP(C) in specific, cholesterol-sensitive membrane microdomains, commonly called lipid rafts.
107 raction of SHP-1 constitutively localizes to membrane microdomains, commonly referred to as lipid raf
108 vation and demonstrate the essential role of membrane microdomain compartmentalization in enabling PI
109 gether, these results suggest that different membrane microdomain components are recruited in a stepw
110 he first time that dietary DHA alters T cell membrane microdomain composition and suppresses the PKCt
111 Unfortunately, little is known about how membrane microdomain composition controls factor VIIa-ti
112 oth clathrin-deficient and clathrin-enriched membrane microdomains concurrent with diminished tyrosin
114 APP induced the formation of cellular plasma membrane microdomains containing dense lipids, in additi
115 myelin-associated glycoprotein (MAG) require membrane microdomains containing either sulfatides or co
118 rkably, both serum EV-enriched fractions and membrane microdomains containing the acquired MHC alloan
119 The ExPortal of Streptococcus pyogenes is a membrane microdomain dedicated to the secretion and fold
120 h active clustering of relevant molecules in membrane microdomains defined as the supramolecular acti
122 e (AMPH) induced DAT-meditated DA efflux and membrane microdomain distribution of the transporter.
123 ne-induced DAT-mediated dopamine efflux, and membrane microdomain distribution of the transporter.
125 roteomic quantitation of detergent resistant membrane microdomains (DRMMs) isolated from cells expres
126 ted with Ib, after which detergent-resistant membrane microdomains (DRMs) were extracted with cold Tr
127 eins that associate with detergent-resistant membrane microdomains (DRMs), which are known to be invo
128 ficial membrane bilayers containing discrete membrane microdomains encompassing T cell ligands (i.e.,
129 ogenes is an anionic phospholipid-containing membrane microdomain enriched in Sec translocons and pos
130 t a reporter protein to Pd, likely to plasma membrane microdomains enriched at Pd As such, the GPI mo
135 f photoreceptor CNG channel association with membrane microdomains enriched in raft lipids, cholester
136 strating the presence of detergent-insoluble membrane microdomains enriched in sterols and sphingolip
137 e viral RdRP and host factors to subcellular membrane microdomains enriched with specific phospholipi
138 bined with their residence in lipid-enriched membrane microdomains facilitates rapid, high-capacity s
139 IV-1) relies on cholesterol-laden lipid raft membrane microdomains for entry into and egress out of s
140 lesterol-dependent CEACAM localizations into membrane microdomains for MHV entry, instead suggesting
148 argeting of ion channels to cholesterol-rich membrane microdomains has emerged as a novel mechanism o
149 Lipid rafts, sterol- and sphingolipid-rich membrane microdomains, have been extensively studied in
150 known to be compartmentalized within plasma membrane microdomains; however, the underlying mechanism
151 Lipid rafts and caveolae are specialized membrane microdomains implicated in regulating G protein
152 agic pathway and the recruitment to specific membrane microdomains in a physiological human gene expr
154 We examined the surface distribution of raft membrane microdomains in cortical neuron cultures during
157 ion is to colocalize signaling proteins with membrane microdomains in order to facilitate their inter
158 idence for a critical role of Flot1-enriched membrane microdomains in PKC-triggered DAT endocytosis a
161 also required to localize DAT within plasma membrane microdomains in stable cell lines, and was esse
166 itutively and exclusively localized to these membrane microdomains in various experimental models.
167 ese findings demonstrate a critical role for membrane microdomains in vesicular trafficking-mediated
168 l a novel modality by which n-3 PUFA remodel membrane microdomains in vivo and thereby alter caveolae
169 x protein (M protein) partitions into plasma membrane microdomains in VSV-infected cells as well as i
171 pose in Cell that expansion of intracellular membrane microdomains induced by saturated FA recruit an
172 which the formation of specific sphingolipid membrane microdomains initiates signaling cascades that
173 ch as secretion, endocytosis, segregation in membrane microdomains, intracellular transport, and targ
177 d DR4 and DR5, respectively) into lipid raft membrane microdomains is required for TRAIL-induced cell
179 with cholesterol- and sphingolipid-enriched membrane microdomains (lipid rafts) and are highly expre
180 that cholesterol- and sphingolipid-enriched membrane microdomains (lipid rafts) mediate specific gui
181 k) signaling module from the GM1-rich plasma membrane microdomains (lipid rafts), and subsequently an
182 that it may partition into cholesterol-rich membrane microdomains (lipid rafts), its compartmentaliz
185 ng of MOG into glycosphingolipid-cholesterol membrane microdomains ("lipid rafts"), followed by chang
186 tein Gag associates with two types of plasma membrane microdomains, lipid rafts and tetraspanin-enric
187 that CD11b/CD18 bound APC within specialized membrane microdomains/lipid rafts and facilitated APC cl
188 ed sGC activity related to dynamic shifts in membrane microdomain localization, with Cav3-microdomain
195 he distribution of single LTCCs in different membrane microdomains of nonfailing and failing human an
196 roscopy showed that both were organized into membrane microdomains of similar sizes, approximately 10
197 GluR1, and ERK all reside within specialized membrane microdomains of the DH, and that ERalpha and ER
200 at preclustering of MHC-peptide complexes in membrane microdomains on the APC surface affects the eff
202 locates and concentrates in cholesterol-rich membrane microdomains or lipid rafts, facilitating forma
206 ns unknown whether this channel localizes in membrane microdomains or whether it interacts with chole
207 zed, and the involvement of cholesterol-rich membrane microdomains, or lipid rafts, in the life cycle
209 Our results indicate that cholesterol-rich membrane microdomains play a role in transmitting non-ge
210 r luminal acidification nor cholesterol-rich membrane microdomains play essential roles in soluble co
211 Epidermal growth factor receptor (EGFR) at membrane microdomains plays an essential role in the gro
212 embrane compositions, engineering metastable membrane microdomains, probing 2D lipid-lipid mixing, an
213 physiological functions, and its presence in membrane microdomains (rafts) appears to be important fo
216 a are co-enriched in cholesterol-rich plasma membrane microdomains/rafts purified from N2a cells.
217 partitioning of Rac1 to caveolin-containing membrane microdomains, raising the possibility that MIF
218 signaling events compartmentalized by these membrane microdomains, recent studies have revealed the
219 to occur via multiple mechanisms, including membrane microdomains, receptor oligomerization, and pro
222 ch lateral segregation into specialized raft membrane microdomains regulates the activable pool of nA
224 ling, and indicate that septins may organize membrane microdomains relevant to other signalling proce
228 ectively partitioned into specialized plasma membrane microdomains rich in glycosphingolipids and cho
230 cellular model, we found LRRK2 to locate to membrane microdomains such as the neck of caveolae, micr
234 these diverse activities, we examined plasma membrane microdomains termed eisosomes or membrane compa
237 MHC-II also associates with another type of membrane microdomain, termed tetraspan microdomains.
238 (MHC-II) associate with detergent-resistant membrane microdomains, termed lipid rafts, which affects
241 ex and dynamic topographical organization of membrane microdomains than is predicted by biochemical a
242 oligovalent ligation positions the BCR in a membrane microdomain that is distinct from one engaged i
244 of EPCR is localized on the cell surface in membrane microdomains that are positive for caveolin-1.
247 hymal cells contain discrete Par3-expressing membrane microdomains that become restricted to an apica
249 fic MHC class II-peptide complexes in plasma membrane microdomains that can facilitate efficient T ce
250 nduces the formation of cholesterol-enriched membrane microdomains that compartmentalize its activate
251 gest the formation of phosphatidate-enriched membrane microdomains that contain all components of the
253 endowed with caveolae, which are specialized membrane microdomains that facilitate the integration of
254 st the existence of lipid rafts, specialized membrane microdomains that promote interaction among sig
255 thelial cells have been implicated as plasma membrane microdomains that sense or transduce hemodynami
256 athways and becomes concentrated in specific membrane microdomains that serve as signaling platforms.
257 s the inherent property of partitioning into membrane microdomains that then serve as the sites of as
258 -sensitive nAChR might reside in specialized membrane microdomains that upon cholesterol depletion be
259 s indicate that NaPi protein is localized in membrane microdomains, that in potassium deficiency a la
262 lation affected the association of GP64 with membrane microdomains, the potential association of GP64
263 sion by condensing CEACAMs into "lipid raft" membrane microdomains, thereby creating opportunities fo
264 gulate the integration and/or coalescence of membrane microdomains, thereby establishing apical-basal
265 ass II complexes are clustered in APC plasma membrane microdomains, thereby providing a mechanism for
267 specific effectors into function-specifying membrane microdomains to carry out receptor trafficking.
269 redistributes from nonlipid raft (LR) to LR membrane microdomains upon immunoglobulin G-red blood ce
270 a1- and beta2-adrenergic receptor-associated membrane microdomains using a novel membrane-targeted Fo
271 n when we prevented it from associating with membrane microdomains via the GPI anchor or when we inhi
272 flotillin, an intrinsic constituent of these membrane microdomains, via the adapter protein, c-Cbl as
273 junction with the known heterogeneity of OHC membrane microdomains, voltage-gated ion channels, charg
274 particles that bud from GSL-enriched plasma membrane microdomains was also dependent on interactions
275 rine substitutions (4S) failed to cluster in membrane microdomains, was deficient in restriction of p
276 To visualize the FAK activity at different membrane microdomains, we develop a fluorescence resonan
277 herin and their affiliation with "raft-like" membrane microdomains were modified by these cytokines.
278 nalog, the L-threo analog did not cluster in membrane microdomains when added at higher concentration
279 ramatically increased by targeting it to the membrane microdomains where fusion occurs, via the addit
280 d-rafts and can target functional enzymes to membrane microdomains where pathologic APP-processing is
281 t activated PKCalpha is recruited to FR-rich membrane microdomains where, in association with its rec
282 P and BACE1 were colocalized into stabilized membrane microdomains, where the beta-cleavage of APP an
283 CMA, only occurs outside the lipid-enriched membrane microdomains, whereas the LAMP-2A located withi
285 assembly platforms might involve sterol-rich membrane microdomains, which are heterogeneous and highl
287 ves in growth, signaling, and maintenance of membrane microdomains, which may arise from the unique c
288 hat facilitate the formation of postsynaptic membrane microdomains, which may serve key roles in the
289 activity is evenly distributed at different membrane microdomains, while integrin-mediated signaling
290 annel localizes in caveolae, which are known membrane microdomains whose major component in the stria
291 t required to concentrate the G protein into membrane microdomains with a density similar to that of
292 d in plasma membranes of infected cells into membrane microdomains with diameters of 100 to 150 nm, w
293 e G protein was organized predominantly into membrane microdomains with diameters of approximately 10
295 ible mechanisms: (i) clustering of PIP(2) in membrane microdomains with restricted lateral diffusion,
296 ergents, indicative of their co-residence in membrane microdomains with similar protein-lipid composi
297 in2 [6-8], is sufficient to generate de novo membrane microdomains with some of the predicted propert
298 have been reported to localize to different membrane microdomains, with H-Ras localizing to caveolin
299 esponsiveness of Ca2+ signaling complexes at membrane microdomains, with the most responsive complexe
300 strategy to explore the function of BACE1 in membrane microdomains without altering the cellular chol