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1 e in the Schlemm's canal (SC) and trabecular meshwork.
2 links on the nuclear envelope and the lamin meshwork.
3 ate at the Golgi and form a dense non-radial meshwork.
4 s performed to 360 degrees of the trabecular meshwork.
5 in combination with a model keratocyte actin meshwork.
6 ncapsulate agarose in the form of a gel-like meshwork.
7 outflow obstruction distal to the trabecular meshwork.
8 ior cornea initiating beneath the trabecular meshwork.
9 acaques by laser treatment to the trabecular meshwork.
10 ctility of the cortical membrane-bound actin meshwork.
11 pigmentary dispersion within the trabecular meshwork.
12 nal with no visible damage to the trabecular meshwork.
13 acaques by laser treatment to the trabecular meshwork.
14 e gelled into a tightly linked, low mobility meshwork.
15 single lamin filaments in three-dimensional meshwork.
16 res, Schlemm's canal (SC) and the trabecular meshwork.
17 ility of the break to traverse the chromatin meshwork.
18 tile stress generated by the platelet-fibrin meshwork.
19 ciliary muscle (46 +/- 5.6%) and trabecular meshwork (37 +/- 8.3%) of treated eyes relative to vehic
20 ose found in normal (5 kPa) and glaucomatous meshworks (75 kPa), or tissue culture polystyrene (TCP;
23 -dependent adhesion organizes the microvilli meshwork and ensures the proper attachment of RCs to the
25 rats was associated with fibrotic trabecular meshwork and increased levels of F-actin, phosphorylated
26 lating DN-Ts are trapped within stromal cell meshwork and interfere with correct localization of MZ B
27 link the plasma membrane and cortical actin meshwork and mediate the dynamic nature of the membrane-
28 showed that chromatin decondensation, lamin meshwork and NE rupture and extracellular DNA release re
30 aqueous humor outflow through the trabecular meshwork and Schlemm's canal (SC) is the most important
31 hin human retina, optic nerve and trabecular meshwork and that ABCA1 and AFAP1 are also expressed in
32 sicles are enmeshed in an apical cytokeratin meshwork and that Rab11a likely acts upstream of Rab8a t
33 nvelope (NE) permeabilization, nuclear lamin meshwork and then NE rupture to release DNA into the cyt
34 actin cytoskeleton is organized into diverse meshworks and bundles that support many aspects of cell
35 to the anterior chamber angle and trabecular meshwork, and reduced postoperative use of steroids.
38 bjects were analyzed to determine trabecular meshwork anteroposterior length and 3 anterior chamber a
39 cant positive association between trabecular meshwork anteroposterior length and all anterior chamber
40 cant positive association between trabecular meshwork anteroposterior length and all anterior chamber
41 evaluate the association between trabecular meshwork anteroposterior length and anterior chamber ang
47 lamins A/C or lamin B1, the remaining lamin meshworks are altered compared with the lamin meshworks
49 in ionically cross-linked MDP into a fibrous meshwork as determined by scanning and transmission elec
50 utilize graphene, a single-atom-thick carbon meshwork, as the thinnest possible impermeable and condu
51 y hypomorphic Schlemm's canal and trabecular meshwork, as well as elevated IOP, demonstrating that an
53 e perpendicular distance from the trabecular meshwork at 500 mum and 750 mum anterior to the scleral
54 to SMLM, in the context of the fibrous actin meshwork at the T cell immunological synapse, whose stru
55 data showed a crucial role for a contractile meshwork at the top of the cell, which is composed of ac
56 define the architecture of the nuclear lamin meshworks at molecular resolution, providing insights in
57 (w/v) readily diffused through the vitreous meshwork; at higher concentrations (~0.1% w/v), these na
60 nt proteins that assemble into a filamentous meshwork, bridging the nuclear envelope and chromatin.
61 ntain the high density of actin filaments in meshwork by keeping actin filaments close enough for cro
62 le, or mechanical blockade of the trabecular meshwork by protein aggregates or contaminant particles
64 restructuring and constraining the spectrin meshwork can fully account for the observed changes in d
65 structures that resemble clumps, stars, and meshworks can appear in the process of ring assembly.
66 stic forces transmitted by the peptidoglycan meshwork cause the moving dislocations to interact not o
67 primary cultures of living human trabecular meshwork cells (hTMC) without the application of exogeno
68 vitro by infecting primary human trabecular meshwork cells and in vivo by injecting living rats intr
69 ork, which is a scenario toxic to trabecular meshwork cells and leads to early onset of ocular hypert
70 d several other ECM components in trabecular meshwork cells from the anterior segment of the eye was
72 misfolding and aggregation within trabecular meshwork cells, and ultimately, ER stress-induced cell d
73 increase oxidative damage to the trabecular meshwork cells, resulting in elevation of intraocular pr
76 of NTRs, penetrate more readily into the FG-meshwork compared to their globular counterparts of iden
77 Our data suggest that a perinuclear actin meshwork connects actin cables to nuclei via actin-cross
79 rround themselves with a cell wall, a strong meshwork consisting primarily of the polymerized aminosu
80 dicted that actin filaments of the endocytic meshwork continually polymerize and disassemble, turning
81 tracellular matrix expression and trabecular meshwork contractility appears to coordinately impact ou
82 n silico model of two-dimensional actomyosin meshwork contraction, demonstrating that actomyosin mesh
86 aterial consisting of a porous elastic solid meshwork (cytoskeleton, organelles, macromolecules) bath
88 Our study also suggests that these MyosinII meshworks drive cell shape changes in response to extern
89 rization of cellular fibronectin (FN) into a meshwork drives endothelial cell (EC) polarity and vascu
90 agination and because of entanglement of the meshwork due to its dendritic structure and cross-linkin
92 k contraction, demonstrating that actomyosin meshworks exhibit an inherent force orienting mechanism
93 yocilin is a protein found in the trabecular meshwork extracellular matrix tissue of the eye that pla
94 uclei lacking LA/C exhibit slightly enlarged meshwork faces and some shape changes, whereas LB1-defic
97 m regions within the uveal and corneoscleral meshwork for image acquisition pairs of AF-SHG (without
98 oA knockout reduced fibroblast branching and meshwork formation and resulted in more compactly cluste
99 ture medium not only rescued the microfibril meshwork formation in LTBP2-suppressed ciliary epithelia
100 rane microdomains induce actin-microfilament meshwork formation, anchoring microtubules that grow rad
102 mber of edges per face, suggesting that each meshwork has somewhat unique assembly characteristics.
103 ted in regions where the fibers in the lamin meshwork have a greater separation, and we find that thi
104 In this clinic-based population, trabecular meshwork height is shorter in PACG patients compared to
107 rin red staining in primary human trabecular meshwork (HTM) cells and alkaline phosphatase (ALP) acti
108 ed from primary cultures of human trabecular meshwork (HTM) cells has confirmed secretion of ATX and
109 mine if oxidative stress on human trabecular meshwork (HTM) cells influences the stability of key mRN
112 human cortical neuronal (HCN-1A), trabecular meshwork (HTMC), and pulmonary artery smooth muscle (PAS
113 egrity, leads to the collapse of the laminB2 meshwork, impairs neuronal survival, and markedly reduce
117 Oxidative stress/damage to the trabecular meshwork in such post-vitrectomy cases may contribute to
118 ereas the MT cytoskeleton resembles a random meshwork in the cells' interior, MTs near the cell surfa
120 mbly, before the appearance of a dense actin meshwork in the initial segment, and before dendrites ac
121 el for modulation of a dynamic actin-vesicle meshwork in the oocyte at the origin of asymmetric posit
123 eshworks are altered compared with the lamin meshworks in wild-type nuclei or nuclei lacking lamin B2
124 n cross-members and the size of the skeletal meshwork increase in developing gametocytes, then decrea
125 fication inducer BMP2 gene to the trabecular meshwork induces elevated IOP in living rats without alt
126 rstood but has been attributed to trabecular meshwork injury from repeated injections, a potential to
127 ed rat hippocampus are affected by astrocyte meshwork integrity: evidence of a novel cell-cell interg
129 us humor (AH) outflow through the trabecular meshwork is a primary risk factor for open-angle glaucom
132 Graph theory analysis shows that the lamin meshwork is not a random arrangement of filaments but ex
134 quantitative analysis reveals that the actin meshwork is organized radially and is compacted by the c
135 aqueous drainage tract distal to trabecular meshwork is potentially an important determinant of intr
136 nced glaucoma suggesting that the trabecular meshwork is the primary impediment to outflow and its ab
139 blocks of the nuclear lamina, a filamentous meshwork lining the nucleoplasmic side of the inner nucl
140 d above the cuticular plate, a dense F-actin meshwork located underneath the apical plasma membrane.
141 ting fibrotic activity within the trabecular meshwork may result in ocular hypertension, we investiga
143 it is difficult to dissect mouse trabecular meshwork (MTM) tissues and establish MTM cell strains.
145 angles were defined as posterior trabecular meshwork not visible for >/=2 quadrants on non-indentati
146 e aligned in tightly bundled chains within a meshwork of astrocytes; however, the cell-cell cues that
147 ) makes it possible to investigate the dense meshwork of axons, dendrites, and synapses that form neu
148 oplasmic astrocytes develop a dense ramified meshwork of cellular processes to form intimate contacts
149 llular matrix (ECM) is a complex and dynamic meshwork of cross-linked proteins that supports cell pol
151 of neutrophil extracellular traps (NETs), a meshwork of decondensed chromatin lined with histones an
152 largely consisting of T cells embedded in a meshwork of epithelial cells, with no direct resemblance
153 bound compartments, which accumulate a dense meshwork of F-actin through the kinase activity of the S
154 clots develop a remarkable structure, with a meshwork of fibrin and platelet aggregates on the exteri
155 components of the nuclear lamina, a dynamic meshwork of intermediate filaments lining the nuclear en
158 nuclear morphology is the nuclear lamina, a meshwork of intermediate lamin filaments that lines the
159 cal effects pertaining to the formation of a meshwork of interpenetrating HA polymer chains are respo
162 n of mechanical stress along the protein/DNA meshwork of meiotic chromosome axes, with topoisomerase
163 sin-1 are initially directed by a disordered meshwork of microtubules, generating minor slow cytoplas
164 agulation was then applied to the trabecular meshwork of one eye to induce chronic elevation of intra
165 agulation was then applied to the trabecular meshwork of one eye to induce chronic elevation of IOP a
166 agulation then was applied to the trabecular meshwork of one eye to induce chronic unilateral IOP ele
170 al extracellular matrix (ECM), an interwoven meshwork of proteins, glycoproteins, proteoglycans, and
171 osterior zonular fibers consisted of a dense meshwork of radially oriented microfibrils that we terme
172 vealed that RPMs are embedded in a reticular meshwork of red pulp fibroblasts characterized by the ex
174 erved in large fish and amphibian eggs are a meshwork of short, unstable microtubules maintained by a
175 We show that the quality of the BM stromal meshwork of SMZL infiltrates correlates with time to pro
176 cell membrane skeleton is a pseudohexagonal meshwork of spectrin, actin, protein 4.1R, ankyrin, and
177 Because the endothelial surface layer, a meshwork of surface-bound and loosely adherent glycosami
179 arrest of compaction of the loose interwoven meshwork of the fetal myocardial primordium and subseque
180 t spanin-mediated fusion is regulated by the meshwork of the PG, thus coupling fusion to murein degra
181 atial boundaries within the dense astroglial meshwork of the SVZ and rostral migratory stream (RMS),
183 f ERK1/2 was also observed in the trabecular meshwork of transgenic mice expressing 6-fold higher lev
184 -bundling activities; the formation of large meshworks of Coro1A(E26K)-decorated filaments endowed wi
185 ructural stability of the nucleus comes from meshworks of intermediate filament proteins known as lam
186 e-it module is illustrated by application to meshworks of nuclear lamin A, minifilaments of myosin II
187 imate forces exerted by a polymerizing actin meshwork on an invagination of the plasma membrane durin
189 ent on filopodial protrusions appearing as a meshwork on the cell surface, which colocalized with CXC
195 types of insoluble organic matrices: chitin meshworks, organic microrings, and organic microplates,
196 a crescent interest in increasing trabecular meshwork outflow by extracellular matrix remodeling and/
197 of new agents that act mainly on trabecular meshwork outflow may be the future hypotensive treatment
198 citatory synapses and in other dense protein meshworks, owing to an impeded diffusion of the ~3,000-k
201 s (8/10) showed moderate to heavy trabecular meshwork pigmentation and either Krukenberg spindle or t
203 y increasing the connectivity of the F-actin meshwork, plastin enables the cortex to generate stronge
205 of glaucoma, pigmentation of the trabecular meshwork (PTM), total energy delivered, and baseline int
206 inted-end rootlets anchored in a filamentous meshwork referred to as the "terminal web." Although cla
209 e uveal (UV), CS, and juxtacanalicular (JCT) meshwork, respectively, were captured at different depth
216 red for formation of the cytoplasmic F-actin meshwork that controls the central position of the spind
217 late assembly of a dynamic cytoplasmic actin meshwork that facilitates translocation of the meiotic s
218 s the basic constituent of the proteinaceous meshwork that is localized between adjacent cytoplasmic
219 tically organize a dynamic cytoplasmic actin meshwork that mediates translocation of the spindle towa
221 protein (ARP)2/3 complex generates an actin meshwork that operates within a tip-localized, microtubu
222 ermediate filaments (DIFs) form an intricate meshwork that organizes myofibers within striated muscle
223 orming a porous and highly dynamic polymeric meshwork that percolates in radial and axial directions
224 mutant of FAK led to disruption of the actin meshwork that resulted in sequestration of IAV at the ce
226 s typically defined as a thin layer of actin meshwork that uniformly underlies the plasma membrane of
227 rA family assembles into a three-dimensional meshwork that uses the nucleoid as a scaffold and period
228 from Def(++) mice were composed of a fibrin meshwork that was denser and contained a higher proporti
229 a minimal continuum elastic model of a lamin meshwork that we use to investigate which aspects of the
230 f molecular processes (expansions of protein meshworks) that are required for degradation of protein
231 of the most abundant genes in the trabecular meshwork, the eye tissue responsible for maintenance of
232 ents may be more localized to the trabecular meshwork, therefore making GATT a particularly suitable
235 luation revealed a well-organized trabecular meshwork tissue, exhibiting denser matrix in the treated
236 nd in the extracellular matrix of trabecular meshwork tissue, the anatomical region of the eye involv
237 sed in most tissues including the trabecular meshwork (TM) and heterozygous Sod2 knockout mice exhibi
238 tors in primary cultures of human trabecular meshwork (TM) and Schlemm's canal (SC) cells were determ
240 The IOP is maintained by the trabecular meshwork (TM) and the elevation of IOP in open-angle gla
243 n and distribution of MRP4 in the trabecular meshwork (TM) cells and its role in homeostasis of IOP.
244 n the modulation of the volume of trabecular meshwork (TM) cells and, in turn, the aqueous humour (AH
245 (ECM) proteins were evaluated in trabecular meshwork (TM) cells by cDNA microarray, q-PCR, fluoresce
246 determine whether cultured human trabecular meshwork (TM) cells express BMP1, BMP1 expression is reg
247 s by compromising the function of trabecular meshwork (TM) cells in the anterior eye, but how these c
248 hyme-like transition (Endo-MT) of trabecular meshwork (TM) cells is known to be associated with prima
249 We have previously shown that trabecular meshwork (TM) cells might detect aqueous humor fluid she
250 age of the phagocytic property of trabecular meshwork (TM) cells, and developed a novel magnetic bead
252 ogical mechanisms of glaucomatous trabecular meshwork (TM) damage and elevation of intraocular pressu
253 open angle glaucoma and is due to trabecular meshwork (TM) damage, which leads to impaired aqueous hu
256 nduced myocilin expression in the trabecular meshwork (TM) has been suggested to play an important ro
258 ever, their potential role in the trabecular meshwork (TM) in the eye, which regulates intraocular pr
262 ular matrix (ECM) proteins in the trabecular meshwork (TM) is associated with TM dysfunction and intr
264 nges in the unlasered portions of trabecular meshwork (TM) of laser-treated primate eyes are understu
267 fluorescence (TPEF) of the human trabecular meshwork (TM) reveals beams of heterogeneous autofluores
268 e study was designed to determine trabecular meshwork (TM) stiffness and its relationship to outflow
269 ermine the localization of TNC in trabecular meshwork (TM) tissue and to analyze the effects of TNC o
272 e biomechanical properties of the trabecular meshwork (TM), including the inner wall of Schlemm's can
273 t-like) from cells located in the trabecular meshwork (TM), the primary structural component of the c
282 olases must break peptide cross-links in the meshwork to allow insertion of new glycan strands betwee
284 is unclear whether rapsyn first forms a wide meshwork to which receptors can subsequently dock or whe
285 alicular connective tissue of the trabecular meshwork together with inner wall endothelium of Schlemm
287 diate filament proteins that assemble into a meshwork underneath the inner nuclear membrane, the nucl
288 ly assess the structure and dynamics of this meshwork using live-cell superresolution fluorescence mi
290 classified as narrow if posterior trabecular meshwork was not visible and open if the angle was open
292 instead of being secreted to the trabecular meshwork, which is a scenario toxic to trabecular meshwo
293 s present contractile apical-medial MyosinII meshworks, which control the apical area and junctional
295 lamin filaments arrange to form an emergent meshwork whose topology dictates the mechanical properti