ライフサイエンスコーパス: mesodermal

1 cell types that are typically categorized as mesodermal.

2 each germ layer, ectodermal, endodermal, and mesodermal.

3 Here, we show that a mesodermal ABCC (MRP) transporter is necessary for endod

4 nic developmental pathway through successive mesodermal and adipogenic progenitor stages.

5 id oral-aboral patterning of nonskeletogenic mesodermal and ectodermal domains in early development o

6 s indicate that developmental GRNs directing mesodermal and ectodermal specification have undergone m

7 eak-like cell population segregated into the mesodermal and endodermal lineages.

8 ors that have important functions in several mesodermal and endodermal organs, including heart, liver

9 The consequences of disrupted mesodermal and endodermal RA signaling were restricted t

10 100 genes with coordinated expression among mesodermal and endothelial cell types.

11 support the notion that Sall4 regulates both mesodermal and neural development.

12 itively supports a progenitor state for both mesodermal and neural progenitors.

13 orchestrated development of the endodermal, mesodermal, and neural crest tissues.

14 ells initiate stem cell cultures and exhibit mesodermal bias in differentiation assays.

15 , which supports the migration and fusion of mesodermal cardiac precursors.

16 -iPSC have a reduced ability to give rise to mesodermal, cardiac progenitors and mature cardiomyocyte

17 e that controls dynamic actin remodeling and mesodermal cell behaviors during Xenopus gastrulation.

18 w C-cadherin-based contacts with neighboring mesodermal cell bodies.

19 eir self-renewal and balancing neural versus mesodermal cell fate decisions.

20 ishing the proper balance between neural and mesodermal cell fate determination in mouse embryos and

21 Mesodermal cell migration defects in toddler mutants res

22 lts suggest that Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling

23 verexpression of Zic1 and Pax3 in the 10T1/2 mesodermal cell model results in enrichment of these fac

24 itor field, possibly representing an ancient mesodermal cell state that predates the primordial verte

25 ne at different embryonic stages and in four mesodermal cell types is governed by the binding of mult

26 ly, in oral or aboral domains, presaging the mesodermal cell types that will emerge.

27 lacks many of the genes found in bilaterian mesodermal cell types, suggesting that these cell types

28 and that the veg2 lineage also gives rise to mesodermal cell types.

29 ment, the PAAs emerge from nkx2.5-expressing mesodermal cells and connect the dorsal head vasculature

30 By late gastrulation, mesodermal cells become packed as they engage in planar

31 hat the E(+)F(+) fraction at E7.5 represents mesodermal cells competent to respond to TGFbeta1, BMP4,

32 During Drosophila gastrulation, the ventral mesodermal cells constrict their apices, undergo a serie

33 partitioned into the nascent ectodermal and mesodermal cells during cleavage and early gastrulation

34 posterior due to the addition of neural and mesodermal cells from a neuromesodermal progenitor (NMp)

35 strating its ability to remodel chromatin in mesodermal cells from developing embryos and proving a m

36 nomic binding and transcription profiling in mesodermal cells from mouse and human Pax3-induced embry

37 We identify a population of mesodermal cells in a developing invertebrate, the marin

38 blebby transitional morphology of involuting mesodermal cells in a vertebrate embryo.

39 During chicken yolk sac (YS) growth, mesodermal cells in the area vasculosa follow the migrat

40 l cells efficiently promote the emergence of mesodermal cells in the neighboring population through s

41 hat identifies impaired migration of nascent mesodermal cells in the primitive streak as the morphoge

42 MCs fail to repress the transfating of other mesodermal cells into the skeletogenic lineage.

43 A subpopulation of mesodermal cells moving ventrally from the somatopleural

44 Mesodermal cells signal to neighboring epithelial cells

45 fic RNAi screen and discovered 39 factors in mesodermal cells that suppress the proliferation of adja

46 of SoxB1 proteins in the limb bud confers on mesodermal cells the potential to activate neural-specif

47 s mediated by regulation of Wnt signaling in mesodermal cells through activation of integrin-beta1.

48 and Gata2 is required in both ectodermal and mesodermal cells to enable mesoderm to commit to a hemat

49 oup Orthoptera, the induction of a subset of mesodermal cells to form the primordial germ cells (PGCs

50 ientation and migration behaviors of lateral mesodermal cells undergoing convergence and extension mo

51 -11/planar cell polarity signaling polarizes mesodermal cells undergoing convergent extension during

52 ntified unanticipated regulatory networks in mesodermal cells with growth-suppressive function, expos

53 n, canonical Wnts promote the recruitment of mesodermal cells within this region into the pacemaker l

54 ially-injected undifferentiated-iPSCs, day 4 mesodermal cells, and day 8, day 20, and day 30 purified

55 RA, produced by newly generated mesodermal cells, provides feedback that initiates NMP g

56 ly coordinated manner across endothelial and mesodermal cells.

57 endodermal and extraembryonic but mixed with mesodermal cells.

58 nal-mediated induction of a subpopulation of mesodermal cells.

59 ing sorted nuclei and interfered with Ubx in mesodermal cells.

60 iate into Pax6(+)-neural precursor cells and mesodermal cells.

61 the separation and intercalation of dividing mesodermal cells.

62 foster tissue repair, and differentiate into mesodermal cells.

63 is derived from both neural crest cells and mesodermal cells; however, the majority of the bone, car

64 nd Delta (Dl) reveals segmentally reiterated mesodermal clusters ("cardiogenic clusters") that consti

65 Finally, because our assay for mesodermal commitment is quantitative we are able to sho

66 isms underlying human embryonic development, mesodermal commitment, and cardiovascular specification.

67 Furthermore, in the mesodermal compartment, genes regulating presomitic meso

68 development is separable from neural and/or mesodermal contributions.

69 nitors become temporarily sequestered in the mesodermal cores of pharyngeal arch 2 (PA2), where they

70 has not been characterised for this class of mesodermal CRMs.

71 strongest case producing embryos with severe mesodermal defects that phenocopy brachyury null mutants

72 after endodermal deletion of Nkx2.5 whereas mesodermal deletion engendered cardiac defects almost id

73 er injury, with putative quiescent precursor mesodermal derivation.

74 a new paradigm for how the kidney and other mesodermal derivatives arise during embryogenesis.

75 st is required to repress gene expression in mesodermal derivatives including muscle and notochord, a

76 f pharyngeal mesoderm and differentiation of mesodermal derivatives into vascular smooth muscle cells

77 specifically abolishes specification of late mesodermal derivatives such as the coelomic pouches to w

78 The ability of neural crest to contribute mesodermal derivatives to the bauplan has raised questio

79 th this, gene expression analysis shows that mesodermal derivatives within the trunk and tail of spt

80 but unlike Pax7, which is also expressed in mesodermal derivatives, this enhancer is not active in s

81 e and adults, which led to lethality; in the mesodermal derivatives, which led to pupal lethality; or

82 subsequently in ectodermal, endodermal, and mesodermal derivatives.

83 he body axis encompasses both ectodermal and mesodermal derivatives.

84 enriched in MSCs compared to differentiated mesodermal derivatives.

85 LF4, and POLR2A result in meningiomas in the mesodermal-derived meninges of the midline and paramedia

86 early in cancer development inectodermal and mesodermal-derived tissue-specific stem and progenitor c

87 he intertwined processes of tail elongation, mesodermal development and somitogenesis.

88 says, these results suggest an impairment in mesodermal development capacity during early stages, whi

89 ry to Bmp signalling that otherwise promotes mesodermal development in the posterior epiblast.

90 ectively, this roadmap enables navigation of mesodermal development to produce transplantable human t

91 bx15 is a member of the T-box gene family of mesodermal developmental genes.

92 maintain Polycomb-mediated repression of non-mesodermal developmental regulators, suggesting cooperat

93 We have previously shown that the mesodermal developmental transcription factor Tbx15 is h

94 the primitive streak, as it does not lead to mesodermal differentiation but brings axial progenitors

95 gh-level Wnt signaling is able to accelerate mesodermal differentiation cell-autonomously, just as we

96 sh Tbx16 (Spadetail) is capable of advancing mesodermal differentiation cell-autonomously.

97 Metabolic switching during endodermal and mesodermal differentiation coincides with a reduction in

98 ockdown, embryos fail to gastrulate and show mesodermal differentiation defects that we connect to in

99 how that NDST1 and NDST2 are dispensable for mesodermal differentiation into osteoblasts but necessar

100 Except for their potential for mesodermal differentiation into osteoblasts, the cells a

101 we are able to show that the acceleration of mesodermal differentiation is surprisingly incomplete, i

102 RA does not control pharyngeal mesodermal differentiation to endothelium, but instead p

103 ccompanies the earliest stages of neural and mesodermal differentiation.

104 ates body elongation and balances neural and mesodermal differentiation.

105 It is expressed in mesodermal domains flanking Mmp2-positive glia.

106 In contrast, mesodermal domains vary significantly in closely related

107 core mesoderm, we used Mesp1(Cre) and T-Cre mesodermal drivers in combination with inactivate Tbx1 a

108 tor binding site motifs accurately predicted mesodermal enhancer activity.

109 posing the conserved and selective nature of mesodermal-epithelial communication in development and c

110 ntestinal setting that is not accompanied by mesodermal expression of Barx1, which is necessary for g

111 brates by the genomic complexity and the pan-mesodermal expression territory of Brachyury.

112 ound by Slou, Msh and other HD TFs that have mesodermal expression.

113 and Dfd (in both brachiopods) show staggered mesodermal expression.

114 ls co-express the neural factor Sox2 and the mesodermal factor Brachyury and differentiate into neura

115 yons that recapitulated ontogeny, with early mesodermal factors being expressed before mature endothe

116 stable switch, leading to maintenance of the mesodermal fate and repression of the bipotential progen

117 During vertebrate development, mesodermal fate choices are regulated by interactions be

118 cells to explore how these pathways control mesodermal fate choices in vitro.

119 understanding of the mechanisms that govern mesodermal fate decisions early during embryogenesis.

120 nding of the mechanisms whereby Etv2 governs mesodermal fate decisions early during embryogenesis.

121 ies identify ER71 as a critical regulator of mesodermal fate decisions that acts to specify the hemat

122 id cell fate is suppressed via Nkx2-5 during mesodermal fate determination, and that the Gata1 gene i

123 (low)T(low) entity whose choice of neural or mesodermal fate is dictated by their position in the pro

124 the tail bud(4), WNT signalling promotes the mesodermal fate that is required for sustained axial elo

125 fate and concomitantly skewed toward cardiac mesodermal fate.

126 hese cells are restricted to an intermediate mesodermal fate.

127 t ontogeny that is separable from neural and mesodermal fates.

128 We further demonstrate that a mesodermal Fgf24 convergence cue controlled by Tbx5a und

129 sensory neurons, and reveal a novel role for mesodermal Fgf8 on the early differentiation of the NC a

130 e found that Y397F embryos exhibited reduced mesodermal fibronectin (FN) and osteopontin expression a

131 These findings identify mesodermal foxc1a/b as a direct upstream regulator of et

132 Here we show that sudden loss of the mesodermal gene (Brachyury) from CNH and the mesoderm pr

133 ingle cell level coexpresses pluripotent and mesodermal gene expression programmes.

134 d-type embryos impaired dorsal organizer and mesodermal gene expression without perceptible earlier p

135 ated FGF activity and ectopically maintained mesodermal gene expression, implicating endogenous retin

136 ed inhibition of p53-directed ectodermal and mesodermal gene expression.

137 tem initiates non-interacting endodermal and mesodermal gene regulatory networks in veg2-derived cell

138 n across species and found that Dl activates mesodermal genes at the same threshold levels in melanog

139 ression datasets indicate that regulation of mesodermal genes has diverged more markedly than regulat

140 rmal state by not only activating downstream mesodermal genes, but also by repressing bipotential pro

141 ly derived from angioblasts specified in the mesodermal germ cell layer.

142 runk progenitors normally fated to enter the mesodermal germ layer can be redirected towards the neur

143 e a positive intergenic feedback loop in the mesodermal GRN.

144 ollective migration towards Fgf8a-expressing mesodermal guideposts.

145 from the epiblast, is a discrete part of the mesodermal heart field, and contributes myocardium after

146 Mesodermal identity is specified in a superficial layer

147 By promoting mesodermal identity through manipulation of WNT signalli

148 s a key regulator of the signals involved in mesodermal induction of neural crest.

149 arch artery remodeling stem from the role of mesodermal integrin alpha5beta1 in neural crest prolifer

150 our studies demonstrate a requisite role for mesodermal integrin alpha5beta1 in signaling between the

151 Mesodermal iPSC-derived progenitors (MiPs) can regenerat

152 ic iPSCs and a specifically isolated pool of mesodermal iPSC-derived progenitors (MiPs) toward the st

153 The authors also identified a novel pool of mesodermal iPSC-derived progenitors (MiPs).

154 Using neural and mesodermal landmarks we demonstrate that the functions o

155 iation while up-regulating genes involved in mesodermal lineage decisions.

156 atin remodeling factors confer robustness to mesodermal lineage determination.

157 e for microRNAs (miRNAs) in establishing the mesodermal lineage leading to both HSC emergence and vas

158 ripotency, formation of primitive streak and mesodermal lineage progression are synchronized in EBs.

159 Both adipocytes and osteoblasts share the mesodermal lineage that derives from mesenchymal stem ce

160 postembryonic cell divisions, including the mesodermal lineage.

161 4d is the origin of mesodermal lineages and the germline in many spiralians.

162 Epigenetic changes in adult lung mesodermal lineages are thought to contribute towards di

163 ipotent stem cells toward 80%-99% pure human mesodermal lineages at most branchpoints.

164 .g., neural lineages by Myt1 Isl1, and St18; mesodermal lineages by Pitx1, Pitx2, Barhl2, and Lmx1a;

165 specification and survival of ectodermal and mesodermal lineages during embryoid body formation and u

166 hoices leading from pluripotency to 12 human mesodermal lineages, including bone, muscle, and heart.

167 cell populations contributed to alternative mesodermal lineages, including the cardiac lineage.

168 reviously assumed to be mostly restricted to mesodermal lineages, marks a hESC-derived hepatic progen

169 lopment, although it is expressed broadly in mesodermal lineages.

170 ulator of cellular proliferation via Yes1 in mesodermal lineages.

171 umours arise from endodermal, ectodermal, or mesodermal lineages.

172 Mesodermal loss of Ezh2 leads to the formation of ectopi

173 Unlike the global reduction of Fgf8, mesodermal loss of Fgf8 leads to a deficiency in PG neur

174 ifferentiation; however, the role of PTEN in mesodermal lung cell lineage formation remains unexamine

175 pecification pathway, specifically the early mesodermal marker Brachy-T, the lateral plate mesodermal

176 esodermal marker Brachy-T, the lateral plate mesodermal marker FLK1, and the endothelial-specific mar

177 ent of hESC-derived progenitors expressing a mesodermal marker, platelet-derived growth factor recept

178 essential for the activation of a subset of mesodermal markers in the Xenopus embryo.

179 genes with expression profile similar to the mesodermal master regulator Twist.

180 Cell lineage tracing demonstrated that mesodermal mesenchymal cells including HSCs are the majo

181 Furthermore, differentiation of the mesodermal mesenchymal cells into oval cells was not obs

182 duct ligation surgery-mediated liver injury, mesodermal mesenchymal cells, including HSCs and PFs, di

183 d classical ideas about the contributions of mesodermal mesenchyme and neural crest to particular str

184 Because ectodermal and mesodermal mesenchyme can form in close proximity and gi

185 the cranial neural crest (CNC) and cephalic mesodermal mesenchyme.

186 al crest-derived cells migrate to populate a mesodermal microenvironment, and display cellular functi

187 ate reconstruction suggests that contractile mesodermal midline cells existed in bilaterian ancestors

188 ial motion is typically attributed to active mesodermal migration over the underlying endoderm.

189 and this similarity with planarians suggests mesodermal muscle originated at the base of the Bilateri

190 it into distinct domains that specify future mesodermal, neural, and ectodermal territories.

191 development, the function of the pancreatic mesodermal niche in this process is poorly understood.

192 protocol to bias the differentiation toward mesodermal or endodermal cell lineage.

193 ial for neural induction but dispensable for mesodermal or endodermal differentiation.

194 geting of T to regulatory elements of either mesodermal or PGC genes has implications for differentia

195 helial balance in the development of certain mesodermal organs.

196 The mesodermal origin of Gryllus PGCs and absence of instruc

197 tor function is only disrupted in tissues of mesodermal origin where a significant amount of CTCF is

198 tions of a common systemic immune imbalance (mesodermal origin) with specific patterns of remodelling

199 elf-renewal, differentiation into tissues of mesodermal origin, and expression of phenotypic surface

200 ll populations of ectodermal, endodermal and mesodermal origin.

201 tes demonstrate that the scapula has a mixed mesodermal origin.

202 pporting cell types from both endodermal and mesodermal origins in a hexagonal lobule unit.

203 ards maintenance of pluripotency and favours mesodermal over neural fates upon differentiation, but t

204 that Goosecoid is an essential regulator of mesodermal patterning in mammals and that it has specifi

205 e ablation of Cubilin impairs endodermal and mesodermal patterning, and results in developmental arre

206 restricting CM specification during anterior mesodermal patterning, suggesting that between the two z

207 ulated the neural marker Sox2, causing a pro-mesodermal phenotype with a decreased proportion of neur

208 P) and posterior-like (low activin/high BMP) mesodermal populations.

209 d the precise cellular origins of the larval mesodermal posterior growth zone.

210 neration and migration of axial and paraxial mesodermal precursor cells by regulating EMT.

211 These arise in an Eng(+)Flk1(+) mesodermal precursor population at embryonic day 7.5 (E7

212 o specify mesoderm from a bipotential neural/mesodermal precursor.

213 ation movements place endodermal precursors, mesodermal precursors and primordial germ cells (PGCs) i

214 analyses have suggested a common origin from mesodermal precursors called hemangioblasts, specified i

215 Axial and paraxial mesodermal precursors ectopically accumulate in the PS a

216 embryos, the lineage specification of early mesodermal precursors expressing or not the Forkhead tra

217 tional in vitro studies suggest instead that mesodermal precursors first generate hemogenic endotheli

218 poietic stem cells, ACE identifies embryonic mesodermal precursors responsible for definitive hematop

219 These conditions induced pluripotent mesodermal precursors that give rise to a variety of som

220 se interactions regulate the transition from mesodermal precursors to cardiac progenitor cells (CPCs)

221 m cells (hESCs) revealed that MIXL1-positive mesodermal precursors were enriched for transcripts enco

222 chastic mechanism of PGC specification, from mesodermal precursors, is conserved in vertebrates.

223 CD90(+)CD73(+)CD31(-) multipotent clonogenic mesodermal precursors, which can be isolated and efficie

224 es the endodermal gene regulatory network in mesodermal precursors.

225 cell population, referred to as intermediate mesodermal progenitor (IMP) cells, is capable of unlimit

226 They also elucidate that chd;spt tailbud mesodermal progenitor cells (MPC) behave autonomously an

227 aused by widespread cell death that includes mesodermal progenitor cells that have begun to precociou

228 ular Tbeta4 can stimulate differentiation of mesodermal progenitor cells to a mature mural cell pheno

229 his approach to convert human fibroblasts to mesodermal progenitor cells, including by non-integrativ

230 orly located population of bipotential neuro-mesodermal progenitor cells.

231 rition-responsive reactivation of neural and mesodermal progenitor cells.

232 and endothelial cells develop from a common mesodermal progenitor, the haemangioblast.

233 to mesenchymal transition (EMT) from NMP to mesodermal progenitor.

234 monstrate that KDR(hi)CD31(-) hematovascular mesodermal progenitors (HVMPs) with definitive hematopoi

235 These progenitors, called neural mesodermal progenitors (NMPs), are identified as cells t

236 harbours bipotent progenitors, called neural mesodermal progenitors (NMPs), that contribute to the sp

237 thought to promote the formation of paraxial mesodermal progenitors (PMPs) of the trunk region while

238 was sufficient to activate Scx in mouse limb mesodermal progenitors and mesenchymal stem cells.

239 of Etv2 in the transcriptional regulation of mesodermal progenitors during embryogenesis.

240 ing limb, cartilage cells differentiate from mesodermal progenitors in an ordered process that result

241 tors (NMPs) produce both neural and paraxial mesodermal progenitors in the trunk and tail during vert

242 cranio-facial musculature derive from common mesodermal progenitors that express NKX2-5, ISL1, and TB

243 ent stem zone epiblast, which contains neuro-mesodermal progenitors that progressively generate the s

244 sms that govern lineage specification of the mesodermal progenitors to become endothelial and hematop

245 gnaling during gastrulation and this enables mesodermal progenitors to commit to a blood fate.

246 in actively restraining the specification of mesodermal progenitors to hematopoiesis.

247 roughout vertebrate trunk elongation, motile mesodermal progenitors undergo an order-to-disorder tran

248 significantly down-regulated processes in DS mesodermal progenitors were associated with decreased st

249 ively specify myoblasts from a pool of naive mesodermal progenitors.

250 Mesodermal progeny generated using such small molecules

251 ssion was induced when the isolated paraxial mesodermal progeny were treated with SAG1 (a hedgehog re

252 e effective generation from ESCs of paraxial mesodermal progeny, and to their further differentiation

253 on and propagation of a cell population with mesodermal properties.

254 rough the bilaterally symmetric divisions of mesodermal proteloblast DM'' and ectodermal proteloblast

255 However, symmetric cleavage of the mesodermal proteloblast was rescued by full length const

256 These studies demonstrate that mesodermal PTEN has a key role in controlling the amplif

257 To determine the role of mesodermal PTEN in the ontogeny of various mesenchymal c

258 As acetylated beta-catenin promotes mesodermal rather than neural fate(7), this ultimately l

259 a spatial pattern that maps directly to the mesodermal region, suggesting that mesoderm differentiat

260 cupancy of Lmd-bound regions with additional mesodermal regulators revealed that different transcript

261 res, studies of TF cooccupancy by additional mesodermal regulators, TF binding site determination usi

262 We propose that variation in mesodermal size occurs at a fast evolutionary rate and i

263 organogenesis model to enable a genome-wide mesodermal-specific RNAi screen and discovered 39 factor

264 stem cell (ESC) germ layer specification and mesodermal specification, uncovering combinatorial effec

265 Tbx16 locks cells into the mesodermal state by not only activating downstream mesod

266 cells (EpiSCs), one route advances through a mesodermal state prior to naive pluripotency induction,

267 ient and required via SMAD2/3 to drive mouse mesodermal stem cells towards the tendon lineage ex vivo

268 Although mesodermal stem cells undergo normal rounds of division

269 the device, we identify an anteriorly biased mesodermal stiffness gradient along which cells move to

270 brates is prefigured by reiterated embryonic mesodermal structures called somites.

271 er specifying the axial position relative to mesodermal structures of the hindbrain territory.

272 ormation and dysregulated the development of mesodermal sublineages.

273 Thus, activin/BMP gradients specify distinct mesodermal subpopulations that generate cell derivatives

274 e streak (PS) and patterns subsequently into mesodermal subtypes and organ precursors.

275 etic protein 4 (BMP4) to polarize cells into mesodermal subtypes that reflect mid-primitive-streak ca

276 1 in osteochondro-progenitor (Tbx1(OPKO)) or mesodermal (Tbx1(MKO)) lineage partially recapitulates t

277 sion of a corridor through a less-permissive mesodermal territory.

278 ere, we show that coordination of neural and mesodermal tissue at the zebrafish head-trunk transition

279 Changes in neural or mesodermal tissue configuration arising from defects in

280 austion, and the latter leads to breaches of mesodermal tissue integrity.

281 pathway - being robustly established within mesodermal tissue on the left side only.

282 ing cues specify germ layer contribution and mesodermal tissue type specification of multipotent stem

283 by coordinating the production of neural and mesodermal tissue.

284 t have been one of the earliest functions of mesodermal tissue.

285 production is distributed between neural and mesodermal tissues in the dorsal isolate, and the notoch

286 hancers identified by eFS as being active in mesodermal tissues revealed enriched DNA binding site mo

287 t the functions of RA in aligning neural and mesodermal tissues temporally precede the specification

288 tion, patterning and alignment of neural and mesodermal tissues that are essential for the organizati

289 TACC1 and TACC2, which are also expressed in mesodermal tissues, including somites.

290 mutants exhibit expanded neural and reduced mesodermal tissues, indicating a role of Sall4 in NMP di

291 lier origin of NC, independent of neural and mesodermal tissues.

292 signaling can occur without inducing ectopic mesodermal tissues.

293 trulation and is unlikely to operate through mesodermal tissues.

294 migration phase and aberrantly contribute to mesodermal tissues.

295 the development and homeostasis of multiple mesodermal tissues.

296 Here we show that the mesodermal transcription factor T-box 15 (Tbx15) is high

297 own and putative, previously uncharacterized mesodermal transcription factors.

298 e(7), this ultimately leads to activation of mesodermal transcriptional WNT targets and specification

299 an oncolytic agent extends to nonhematologic mesodermal tumors and that unusually strong resistance t

300 s secreted from the prospective dorsolateral mesodermal zone during gastrulation.