ライフサイエンスコーパス: mesothelial

1 pleural-based therapies to modulate pleural mesothelial activation and parenchymal fibrosis progress

2 We observed that macrophage-mesothelial adhesion is Arg-Gly-Asp (RGD) sensitive and

3 socolon and retroperitoneum are separated by mesothelial and connective tissue layers.

4 data provide a molecular mechanism by which mesothelial and epithelial FGF9 directs lung development

5 Thus, Wt1(+) mesothelial and fibroblastic stromal cells constitute es

6 enes of GATA6(+) macrophages were induced by mesothelial and fibroblastic stromal cells that express

7 uclei, cytoplasm, and extracellular space of mesothelial and inflammatory cells around asbestos depos

8 We demonstrate that WT1 is expressed by both mesothelial and mesenchymal cells in idiopathic pulmonar

9 creased expression of lysyl oxidase (LOX) in mesothelial and ovarian cancer cells to promote collagen

10 signal-regulated kinase (ERK1/2) pathway in mesothelial and pulmonary epithelial cells in vitro, but

11 e divided into two distinct regions: the sub-mesothelial and sub-epithelial compartments, which proli

12 that were cocultured with Jagged-1 knockdown mesothelial and tumor feeder cells.

13 Here, we demonstrate that mesothelial- and epithelial-derived FGF9, mesenchymal Wn

14 n RTK with known oncogenic properties in non-mesothelial cancer types.

15 wth factor-beta1 (TGF-beta1) induces pleural mesothelial cell (PMC) transformation into myofibroblast

16 Furthermore, mesothelial cell and macrophage expression of VEGF-C inc

17 enesis and indicate that signals controlling mesothelial cell entry are organ specific.

18 We visualized WT1(+) mesothelial cell entry into the lung by live imaging and

19 SV40 may be related to the very high rate of mesothelial cell immortalization that is characteristica

20 ory effects of DLX4 on CD44 levels and tumor-mesothelial cell interactions were abrogated when IL-1be

21 gated the ability of DLX4 to stimulate tumor-mesothelial cell interactions.

22 etastasis, potentiating invasion through the mesothelial cell layer and colonization of the submesoth

23 its ability to recruit an entirely exogenous mesothelial cell layer during development.

24 The epicardium, a mesothelial cell layer enveloping the myocardium, is act

25 The epicardium is a mesothelial cell layer essential for vertebrate heart de

26 tant contribution of somatic mesoderm to the mesothelial cell layer of the PE.

27 ovarian cancer metastasis, clearance of the mesothelial cell layer, to examine the clearance ability

28 cin promoted intercalation of filopodia into mesothelial cell layers and cell invasion.

29 A human mesothelial cell line (LP9/TERT-1) and isolated human pl

30 imens (n = 5), and MPM and SV40-immortalized mesothelial cell lines (n = 5).

31 SV40 oncoprotein expression in murine mesothelial cell lines enhanced spontaneous and asbestos

32 Murine mesothelial cell lines lacking wild-type p53 due to a po

33 addition, stress-induced senescence in human mesothelial cell lines was impaired by SV40 oncoprotein

34 immortal cell lines (SV40-transformed human mesothelial cell lines, S-HML).

35 the invasion of tumor cell clusters into the mesothelial cell lining of peritoneal cavity organs; how

36 Activation of mesothelial cell LPA1 induced CTGF expression by inducin

37 BKV replicated faster than SV40 and caused mesothelial cell lysis, not cellular transformation.

38 cancer cell death during adhesion to normal mesothelial cell monolayers.

39 loss-of-function mice, we demonstrated that mesothelial cell movement into the lung requires the dir

40 ary vessels arise from a unique extracardiac mesothelial cell population, the proepicardium, which de

41 ic grafting and subsequent identification of mesothelial cell populations, we demonstrate that a diff

42 gates the role of dynamic O-GlcNAcylation of mesothelial cell proteins in cell survival during exposu

43 ve loads stimulated remodeling of peritoneal mesothelial cell surface ultrastructure via induction of

44 s of erionite, and examined the hallmarks of mesothelial cell transformation in vitro and in vivo.

45 Here, we demonstrate that asbestos-induced mesothelial cell transformation is linked to increases i

46 There was evidence of mesothelial cell transition to a mesenchymal phenotype w

47 We characterize two distinct mesothelial cell types as well as early hepatic stellate

48 The mesothelial cell VEGF production was significantly reduc

49 ally in the developing mesothelium reveals a mesothelial cell-autonomous role for Ezh2 in repression

50 These data suggest that downregulation of mesothelial cell-derived ITLN1 in the omental tumor micr

51 e relationships between epicardium, arterial mesothelial cells (AMCs), and the coronary vasculature.

52 e vertebrate heart originates from migratory mesothelial cells (epicardium) that give rise to coronar

53 ly, we reported that SV40 infection of human mesothelial cells (HM) causes aberrant methylation of th

54 SV40 infection of human mesothelial cells (HM) causes early cellular immortaliza

55 Asbestos is cytotoxic to human mesothelial cells (HM), which appears counterintuitive f

56 er mesothelial cells (SHM) and primary human mesothelial cells (HM).

57 s not induce transformation of primary human mesothelial cells (HM); instead, asbestos is very cytoto

58 1 production were measured in vitro in human mesothelial cells (HMC) in the presence or absence of me

59 We have shown that human peritoneal mesothelial cells (HPMCs) recovered from the pelvic peri

60 Human peritoneal mesothelial cells (HPMCs), the main source of IL-6 and V

61 ffluents, peritoneal tissues, and peritoneal mesothelial cells (HPMCs).

62 ning vesicle transportation in human pleural mesothelial cells (HPMCs).

63 n the developing liver, lung, and intestine, mesothelial cells (MCs) differentiate into specific mese

64 Mesothelial cells (MCs) form a single epithelial layer a

65 Mesothelial cells (MCs) line the peritoneal cavity and h

66 onstrated that MesP1+ mesoderm gives rise to mesothelial cells (MCs), which differentiate into HSCs a

67 13), and primary peritoneal and immortalized mesothelial cells (MeT5A) by immunohistochemistry, qRT-P

68 ies using NIH 3T3 fibroblasts and peritoneal mesothelial cells (PMCs) showed that CTGF blockade suppr

69 Pleural mesothelial cells (PMCs), which are derived from the mes

70 ophils (RNase 3), macrophages (RNase 6), and mesothelial cells (RNase 7).

71 P-1) activity in both primary Syrian hamster mesothelial cells (SHM) and primary human mesothelial ce

72 in peritoneal macrophages (TLR2/4, C5aR) and mesothelial cells (TLR2, C5aR).

73 al steps of OvCa metastasis and suggest that mesothelial cells actively contribute to metastasis.

74 Mesothelial cells also produced chemokines in response t

75 host-derived Wnt5a, expressed by peritoneal mesothelial cells and adipocytes, as a primary regulator

76 Mesotheliomas are tumors arising from mesothelial cells and are associated with asbestos expos

77 SV40 did not lyse mesothelial cells and caused a high rate of transformati

78 lls associated with the basal lamina beneath mesothelial cells and expressing activated leukocyte cel

79 ulture containing primary human fibroblasts, mesothelial cells and extracellular matrix can be adapte

80 reased phosphorylation of Tyr-216 in pleural mesothelial cells and GSK-3beta mobilization from the cy

81 f innate immune mediators from primary mouse mesothelial cells and human monocytic MonoMac6 cells, an

82 rt their ability to colonize and multiply in mesothelial cells and in both resident and recruited leu

83 However, normal mesothelial cells and mesothelioma cells from Bap1(+/-)

84 TNT-mediated interaction between peritoneal mesothelial cells and OvCa cells was enhanced under comp

85 Immortalized human mesothelial cells and primary mesothelial cells, culture

86 y resident macrophages and then amplified by mesothelial cells and probably other cells of the perito

87 data identify distinctive fates for injured mesothelial cells and submesothelial fibroblasts during

88 ty, adhesion to and retraction of peritoneal mesothelial cells and subsequent anchoring.

89 Both production of LPA by peritoneal mesothelial cells and the chemotactic activity in the co

90 submesothelial cells is higher than that of mesothelial cells and transitional cells.

91 n tumor microenvironment, notably peritoneal mesothelial cells and visceral adipose, secreted Wnt5a.

92 Accumulating evidence suggests that mesothelial cells are an important component of the meta

93 In conclusion, mesothelial cells are an important source of VEGF.

94 Mesothelial cells are generally thought to be "bystander

95 on, this study identified O-GlcNAcylation in mesothelial cells as a potentially important molecular m

96 These results define mesothelial cells as microbial sensors through TLRs and

97 ed ovarian tumor cell adhesion to peritoneal mesothelial cells as well as migration and invasion, lea

98 vasculogenic niche composed of AMCs and sub-mesothelial cells at the base of the pulmonary artery.

99 1, Tcf21) and Tbx18, can be induced in naive mesothelial cells by the liver bud, both in vitro and in

100 The heart is lined by a single layer of mesothelial cells called the epicardium that provides im

101 Indeed, knockdown of CD157 in Met-5A mesothelial cells changed their morphology and cytoskele

102 e, for the first time, that human peritoneal mesothelial cells constitutively produce bioactive lipid

103 We show here that human peritoneal mesothelial cells constitutively produce LPA, which acco

104 Pleural mesothelial cells contribute to pleural rind formation b

105 Thus, specialized omental mesothelial cells coordinate the recruitment and aggrega

106 We show that SV40 infection of human mesothelial cells directly causes overexpression of Notc

107 ) three Ca(2+) shuttling pathways in primary mesothelial cells during Ca(2+) oscillations: Ca(2+) shu

108 Mesothelial cells exposed to asbestos or bleomycin for 9

109 Mesothelial cells expressed podoplanin and ALCAM.

110 lly devoid of a mesothelium but that serosal mesothelial cells expressing the Wilm's tumor protein (W

111 Adenoviral-Cre treatment of normal mesothelial cells from Bap1;Nf2;Cdkn2a CKO mice, but not

112 spheroid formation in vitro, suggesting that mesothelial cells from Bap1;Nf2;Cdkn2a mice have stem ce

113 Sub-mesothelial cells from this niche differentiate into lym

114 sion of ovarian cancer cells into peritoneal mesothelial cells has also been analyzed and shown to re

115 Here we show that malignant mesothelial cells have an elevated Notch signaling pathw

116 y assays for PLA(2) indicate that peritoneal mesothelial cells have strong constitutive PLA(2) activi

117 Treatment of mesothelial cells in culture with carboplatin resulted i

118 uption is repaired and replaced by surviving mesothelial cells in peritoneal injury, and not by subme

119 esive nanoparticles (BNPs) can interact with mesothelial cells in the abdominal cavity and significan

120 highlight an important role for hypoxia and mesothelial cells in the modification of the extracellul

121 of transformation in infected primary human mesothelial cells in tissue culture, leading to the form

122 achment of ovarian tumor cells to peritoneal mesothelial cells in vitro and increases the numbers of

123 overexpression of ET-1 induced MMT in human mesothelial cells in vitro and promoted the early cellul

124 Blocking fibronectin production in primary mesothelial cells in vitro or in murine models, either g

125 roduction in pleural tissues in vivo, and by mesothelial cells in vitro.

126 TGF-beta increases the VEGF production by mesothelial cells in vivo and in vitro.

127 r genetic mapping of Wilms' tumor-1-positive mesothelial cells indicated that peritoneal membrane dis

128 Activation of LPA1 on mesothelial cells induced these cells to express connect

129 this activity was undetectable or minimal in mesothelial cells infected and/or transformed by SV40 ta

130 tos did not influence telomerase activity in mesothelial cells infected with SV40.

131 Phenotype conversion of mesothelial cells into myofibroblasts, the so-called mes

132 RK1/2 activation in pulmonary epithelial and mesothelial cells is unclear.

133 mas (MMs) are aggressive tumors derived from mesothelial cells lining the lungs, pericardium and peri

134 g through the mesothelium, a single layer of mesothelial cells lining the peritoneal cavity.

135 Endogenous peritoneal macrophages and mesothelial cells lining the peritoneum contain MCP-1, w

136 Binding of mesothelin on normal mesothelial cells lining the pleura or peritoneum to the

137 mesothelioma (MPeM) is a rare cancer of the mesothelial cells of the peritoneum.

138 Novel findings include the following: mesothelial cells of the serosa transduce Hedgehog signa

139 l ester "mixed isomers" (CCFSE) dye to label mesothelial cells on the surface of the embryonic lung.

140 single-chain urokinase-bound rabbit pleural mesothelial cells or lung fibroblasts with kinetics simi

141 Although primary cultures of mesothelial cells or submesothelial fibroblasts each exp

142 ese findings indicate that cancer-associated mesothelial cells promote colonization during the initia

143 However, the mechanisms by which mesothelial cells promote metastasis are unclear.

144 Upon exposure to bacterial products, mesothelial cells secrete chemokines, but the signaling

145 pic 3D cultures, we found that primary human mesothelial cells secrete fibronectin in the presence of

146 Together, our data provide evidence that mesothelial cells serve as a source of vascular smooth m

147 line (LP9/TERT-1) and isolated human pleural mesothelial cells showed rapid and protracted asbestos-i

148 A subset of mesothelial cells situated atop the immune aggregates wa

149 Conditioned medium from peritoneal mesothelial cells stimulate migration, adhesion, and inv

150 nd, VCAM-1, inhibits EMT of chick epicardial mesothelial cells stimulated by TGFbeta isoforms.

151 ovarian tumor cells as well as in peritoneal mesothelial cells that are in direct contact with dissem

152 ember proto-oncogenes in lung epithelial and mesothelial cells that are linked to proliferation and c

153 ereby favoring survival and proliferation of mesothelial cells that have sustained DNA damage.

154 inflammasome, a component of macrophages or mesothelial cells that leads to production of chemotacti

155 Mesothelial cells that line the serous cavities and oute

156 RAC1/SMAD-dependent signaling pathway in the mesothelial cells that promotes a mesenchymal phenotype

157 s are up-regulated in asbestos-exposed human mesothelial cells through an epidermal growth factor rec

158 hese data demonstrate an intrinsic origin of mesothelial cells to a coelomic organ and provide a nove

159 Recent studies have proposed mesothelial cells to be an important source of myofibrob

160 hesize that SV40 oncoproteins will sensitize mesothelial cells to DNA damage induced by asbestos or c

161 ty of the conditioned medium from peritoneal mesothelial cells to ovarian cancer cells.

162 ccompanied by transport of mitochondria from mesothelial cells to OvCa cells.

163 the unusual susceptibility of primary human mesothelial cells to SV40 carcinogenesis.

164 hese observations support a scenario whereby mesothelial cells undergo a series of chronic injury, in

165 eport that stimulation of primary peritoneal mesothelial cells via nucleotide-binding oligomerization

166 Yet, Nod1 stimulation of mesothelial cells via RICK enhanced chemokine secretion

167 uced inflammasome/inflammation activation in mesothelial cells was CREB dependent, further supporting

168 2, TLR4, TRIF, or inflammasome components in mesothelial cells was critical for the production of CXC

169 ng anti-ALCAM antibodies, submesothelial and mesothelial cells were isolated by FACS.

170 cer cell apoptosis during adhesion to normal mesothelial cells which line the peritoneum.

171 sbestos induces a fibroblastic transition of mesothelial cells with a gain of mesenchymal markers (vi

172 Finally, infection of mesothelial cells with Listeria monocytogenes induced pr

173 Stimulation of human peritoneal mesothelial cells with OSM induced phosphorylation of gp

174 tracellular matrix components, human primary mesothelial cells, and full-thickness human peritoneum a

175 ressed by submesothelial fibroblasts but not mesothelial cells, attenuated the peritoneal fibrosis bu

176 induced telomerase activity in primary human mesothelial cells, but not in primary fibroblasts.

177 ms of interactions of pathogenic fibers with mesothelial cells, crucial signaling pathways, and genet

178 rtalized human mesothelial cells and primary mesothelial cells, cultured from human omentum or clinic

179 also shown to efficiently rupture peritoneal mesothelial cells, exposing the submesothelial collagen

180 BKV and SV40 infected mesothelial cells, expressed viral oncoproteins, and cau

181 31 was mainly derived from the local tissue (mesothelial cells, fibroblasts).

182 on of Wilms tumor 1 (WT1), a known marker of mesothelial cells, in various cell types in normal and f

183 le for this vascular defect was the yolk sac mesothelial cells, not the cardiomyocytes or the VSMC.

184 podoplanin was also expressed by peritoneal mesothelial cells, osteocytes, glandular myoepithelial c

185 In cultured mesothelial cells, TGF-beta1 upregulated the expression

186 We observed that, in primary mesothelial cells, the plasmalemmal Ca(2+) influx played

187 because its normal expression is limited to mesothelial cells, which are dispensable.

188 he direct interaction of the OvCa cells with mesothelial cells, which cover the surface of the omentu

189 nment of chronic IL-1beta signaling in human mesothelial cells, which may promote mesothelial to fibr

190 he surface of FALCs were covered by CXCL1(+) mesothelial cells, which we termed FALC cover cells.

191 entified in the allantois: an outer layer of mesothelial cells, whose distal portion will become tran

192 he O-GlcNAc signal primarily originates from mesothelial cells.

193 ion in normal human tissues is restricted to mesothelial cells.

194 ntum, which are covered by a single layer of mesothelial cells.

195 al effects and transforming actions in human mesothelial cells.

196 lite exposures have similar effects on human mesothelial cells.

197 vide a novel mechanism for the generation of mesothelial cells.

198 n implicated previously in transformation of mesothelial cells.

199 PRRs) in bone marrow-derived macrophages and mesothelial cells.

200 elioma tumor cells in situ but not by normal mesothelial cells.

201 ted in asbestos-induced oncogenesis of human mesothelial cells.

202 in MM cell lines compared with non-malignant mesothelial cells.

203 signaling pathway compared with normal human mesothelial cells.

204 f neutrophils via IL-1R/MyD88 on neighboring mesothelial cells.

205 tumor 1 gene (Wt1) is expressed only in the mesothelial cells.

206 -6 from macrophages but robust production in mesothelial cells.

207 assayed for in vitro cytotoxicity to murine mesothelial cells.

208 ar matrix proteins, as well as to peritoneal mesothelial cells.

209 of chemokine and antimicrobial responses in mesothelial cells.

210 stimulated by angiogenic factors produced by mesothelial cells.

211 red chick embryonic and rat adult epicardial mesothelial cells.

212 pancreatic tissue but not in melanocytes and mesothelial cells.

213 lly expressed in MM cells compared to normal mesothelial cells.

214 in MM cells but had minimal effect on normal mesothelial cells.

215 We found that JCV did not infect human mesothelial cells.

216 l of a cell line derived from rat epicardial mesothelial cells.

217 required for the growth of SV40-transformed mesothelial cells.

218 ristically associated with SV40 infection of mesothelial cells.

219 xpression was restricted to human peritoneal mesothelial cells.

220 ers and is critical to the transformation of mesothelial cells.

221 rease in VEGF production from murine pleural mesothelial cells.

222 signaling enhanced collagen I deposition by mesothelial cells.

223 on of IL-1beta and IL-18 production in human mesothelial cells.

224 ne marrow derived macrophages, as well as by mesothelial cells.

225 orphologies and function compared to control mesothelial cells.

226 expression and TGF-beta1 expression in human mesothelial cells.

227 FA mRNA (P < 0.05) and protein (P < 0.05) in mesothelial cells.

228 sed concentrations of ID1 mRNA (P < 0.05) in mesothelial cells.

229 Acquisition of Ncad by Ecad+ cells increased mesothelial clearance activity but was not sufficient to

230 oneal explants and impaired MCA survival and mesothelial clearance competence.

231 al-to-mesenchymal transition (EMT), promoted mesothelial clearance in cell lines with weak activity,

232 scription factors TWIST1 and ZEB1 attenuated mesothelial clearance in ovarian cancer cell lines with

233 Amphiregulin enhances CL31 mesothelial clearance, a prerequisite for metastasis.

234 promotes cell migration, anoikis resistance, mesothelial clearance, and peritoneal metastasis in vitr

235 tion is maintained in SV40-transformed human mesothelial clones and in SV40-positive mesotheliomas an

236 ish that regeneration of the epicardium, the mesothelial covering of the heart, is mediated by two ph

237 The mesothelial-derived lineage demonstrates punctuated phen

238 nate while the long-studied cardiac model of mesothelial development may be the outlier.

239 Historically, analyses of mesothelial differentiation have focused on the heart wh

240 The mesothelial epicardium lost epithelial gene expression a

241 cancer cells exhibited increased adhesion to mesothelial explants excised from mice modeling diet-ind

242 Mesothelial FGF9 and mesenchymal WNT2A are principally r

243 Mesothelial Fibroblast Growth Factor 9 (Fgf9) has been d

244 edgehog signaling was not required for fetal mesothelial heart entry.

245 ated nuclear CREB1 as compared with reactive mesothelial hyperplasias and normal lung tissue.

246 se MCAs with peritoneal mesothelium disrupts mesothelial integrity, exposing the submesothelial colla

247 c adhesion molecule regulation of macrophage-mesothelial interactions.

248 ons in the regulation of ovarian cancer cell mesothelial invasion and metastatic progression and offe

249 Using a cell culture model system of mesothelial invasion, highly tumorigenic SKOV-3 and ES-2

250 correlates with the presence of an overlying mesothelial layer, which, as in vivo, expresses Fibrobla

251 R3(-/-) mice did not develop fibrosis of the mesothelial layer.

252 Where apposed to retroperitoneum, 2 mesothelial layers separated mesocolon and underlying re

253 show that cells originating from the Wt1(+) mesothelial lineage, which includes epicardial cells, di

254 with 9 mesothelioma cell lines and 3 normal mesothelial lines.

255 atments stimulate macrophage adhesion to the mesothelial lining of the peritoneal cavity.

256 spleen, an organ that originates within the mesothelial lining of the stomach.

257 Inactivation of all three loci in the mesothelial lining of the thoracic cavity leads to a hig

258 bute to pleural rind formation by undergoing mesothelial mesenchymal transition (MesoMT), whereby the

259 notably upregulated during TGF-beta induced mesothelial-mesenchymal transition (MesoMT).

260 These results indicate that MCs undergo mesothelial-mesenchymal transition and participate in li

261 phenotypic plasticity through bidirectional mesothelial-mesenchymal transitions.

262 m the mesothelium (the future pleura) to sub-mesothelial mesenchyme through both FGF receptor (FGFR)

263 more efficient in transmigration through the mesothelial monolayer compared with poorly tumorigenic O

264 neum and induce retraction of the peritoneal mesothelial monolayer prior to invasion of the collagen-

265 ent and extravasation across endothelial and mesothelial monolayers at sites of inflammation.

266 ibit, transmigration of SKOV-3 cells through mesothelial monolayers.

267 omous motion by subtracting the tissue-level mesothelial motion from the total endothelial cell displ

268 The mesothelial niche was enriched with fibrillar collagen i

269 Here, we report that the HGSOC tumor-mesothelial niche was hypoxic, and hypoxic signaling enh

270 anscriptional signature reflecting embryonic mesothelial origin of their discreet quiescent adult pre

271 clusters expressed the YAP1 target gene and mesothelial progenitor marker mesothelin, and many mesot

272 AJB1-PRKACA fusion in a YAP1-dependent liver mesothelial progenitor, identifying YAP1 as a target for

273 era model of gut morphogenesis reveals these mesothelial progenitors are broadly distributed througho

274 In this newly discovered model, mesothelial progenitors are intrinsic to organs of the d

275 Recent studies have shown that mesothelial progenitors contribute to mesenchymal lineag

276 lineage-tracing studies, we demonstrate that mesothelial progenitors of the intestine are intrinsic t

277 ction assays in organ cultures, and targeted mesothelial-restricted hedgehog loss-of-function mice, w

278 In addition, regionalized epicardial/mesothelial retinoic acid signaling regulates lymphangio

279 sis (Affymetrix array) of normal rat pleural mesothelial (RPM) cells, RPM cells exposed to crocidolit

280 lines in comparison to isolated rat pleural mesothelial (RPM) cells.

281 endon and skeletal muscle and underlying the mesothelial/serosal/capsular surfaces of every major org

282 ng after confirming that Cre recombinase was mesothelial specific and faithfully recapitulated endoge

283 hy mice injected with LPA exhibited enhanced mesothelial surface microvilli.

284 is an asbestos-induced cancer arising on the mesothelial surface of organ cavities.

285 In response to cardiac damage, a mesothelial tissue layer enveloping the heart called the

286 ular cell motility as well as the underlying mesothelial tissue motion.

287 ere significantly downregulated in malignant mesothelial tissues and malignant pleural mesothelioma (

288 ssion levels to classify benign vs malignant mesothelial tissues and the differences between pemetrex

289 ferentially expressed in benign or malignant mesothelial tissues.

290 n human mesothelial cells, which may promote mesothelial to fibroblastic transition (MFT) in an NLRP3

291 lso revealed the process of asbestos-induced mesothelial to fibroblastic transition and its ameliorat

292 e the first to suggest that asbestos induces mesothelial to fibroblastic transition in an inflammasom

293 ild-type (WT) mice showed enhanced fibrosis, mesothelial to mesenchymal transition, IL-17 production,

294 ial cells into myofibroblasts, the so-called mesothelial-to-mesenchymal transition (MMT), significant

295 ted the PMC phenotype and showed evidence of mesothelial-to-mesenchymal transition (MMT), with a redu

296 ation and myofibroblast differentiation, PMC mesothelial-to-mesenchymal transition, and VEGF-A produc

297 57BL/6 mice with fibrosis, angiogenesis, and mesothelial-to-mesenchymal transition.

298 Examination of mesothelial ultrastructure revealed a substantial increa

299 tes to and envelops the myocardium supplying mesothelial, vascular and stromal cell lineages.

300 The effects of carboplatin on mesothelial VCAM-1 expression were determined in culture