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1 ltering exon 5 inclusion in SmgGDS pre-mRNA (messenger RNA).
2 h rapid upregulation of thrombopoietin (TPO) messenger RNA.
3 ide, and dimethyloxalylglycine, raised NCOA4 messenger RNA.
4 -surface levels of PVR but not levels of Pvr messenger RNA.
5 ch binds to and prevents translation of TP53 messenger RNA.
6 esponding cis-regulatory elements in the pre-messenger RNA.
7 t cell density and levels of NOTCH3 and JAG2 messenger RNA.
8 t on how ribosomes can ignore stop codons in messenger RNA.
9 elets, suggesting dynamic trafficking of the messenger RNA.
10 uncleaved by ribonucleases and assemble onto messenger RNA.
11 orchestrate maturation and stabilisation of messenger RNA.
12 function for TET-mediated m(5)C oxidation in messenger RNA.
13 within the 3'-untranslated regions of PFKFB3 messenger RNA.
14 ated by binding of CPEB4 to its untranslated messenger RNA.
15 iptionally regulate the expression levels of messenger RNAs.
16 NA binding compared with cytoplasm-localized messenger RNAs.
17 lly drives expression of its own independent messenger RNAs.
18 rom short regulatory transcripts to gigantic messenger RNAs.
19 machinery, preventing the synthesis of viral messenger RNAs.
20 mostly intron retention, in several hundred messenger RNAs.
21 nces within 3'-untranslated regions of those messenger RNAs.
22 h Argonaute (AGO) proteins to repress target messenger RNAs.
23 PAIR-MaP to human RNase MRP and 2 bacterial messenger RNA 5' untranslated regions reveals functional
24 ed blood and urine samples, as well as CXCL9 messenger RNA (a marker of graft rejection) at elevated
26 ukin 6 and interleukin 1 receptor antagonist messenger RNA, alterations in synaptic strength, and nor
27 egulatory elements found mostly in bacterial messenger RNA and are classified into subtypes based on
28 omplex pseudouridine landscape that includes messenger RNA and diverse classes of noncoding RNA in hu
30 is and immunohistochemistry (IHC) to examine messenger RNA and protein changes in glands over time.
31 with sensitive sAML blasts, displayed higher messenger RNA and protein expression of TCF7L2, JMJD6, a
35 revealed significant up-regulation of CXADR messenger RNA and protein levels in plaque-invested caro
36 ared with AA MPs, SS MPs increased EC ICAM-1 messenger RNA and protein levels, as well as neutrophil
43 enzyme-linked immunosorbent assay, and COX2 messenger RNA and protein, compared with control biopsie
44 (m6A) has recently been found abundantly on messenger RNA and shown to regulate most steps of mRNA m
45 ense oligonucleotide designed to inhibit HTT messenger RNA and thereby reduce concentrations of mutan
46 MECP2 deletion altered expression of 284 messenger RNAs and 244 long noncoding RNAs, including th
47 ng nuclear maturation of most eukaryotic pre-messenger RNAs and long non-coding RNAs, introns are rem
50 get genes, followed by reduced expression of messenger RNAs and proteins regulated by the Wnt pathway
51 post-transcriptional regulators that target messenger RNAs and repress their translation into protei
53 t polypeptides that are encoded by defective messenger RNAs and undergo stalling at the ribosome duri
54 d by quantitative polymerase chain reaction (messenger RNA) and enzyme-linked immunosorbent assay (pr
55 cules, some encoding proteins (the so-called messenger RNAs) and others lacking protein-coding potent
57 zymes, determination of the cap structure of messenger RNA, and development of poxviruses as gene exp
58 and SYF2 were found associated with ECT2 pre-messenger RNA, and ECT2-Ex5+ isoform depletion reduced d
59 ed evidence for abasic sites in nascent RNA, messenger RNA, and ribosomal RNA from yeast and human ce
60 d the degradation of several host interferon messenger RNAs, and thus acted as a negative feedback re
66 le epigenetic modification found not only in messenger RNAs but also in non-coding RNAs, m(6)A affect
67 dant in untranslated regions (UTRs) of human messenger RNAs, but their functional importance remains
69 is unclear how newly synthesized genomes and messenger RNAs can travel from these sealed replication
70 tudies indicate that Rpt1- and Rpt2-encoding messenger RNAs co-localize in these particles that conta
71 patients with IBD had reduced levels of CRT messenger RNA compared with those from control individua
72 similar changes in the abundance of specific messenger RNAs, consistent with their ability to produce
77 eated celiac disease had increased levels of messenger RNAs encoding IL15 receptor subunit alpha (IL1
80 6 piRNAs repress gene expression by cleaving messenger RNAs encoding proteins required for sperm func
81 id cells and cells expressing Cxcr2 and Lgr5 messenger RNAs (epithelial progenitors) compared with mi
82 gonad-specific variant of the heterodimeric messenger RNA export receptor Nxf1-Nxt1 and the Piwi-ass
84 promoter, which is required for Bdnf exon IV messenger RNA expression and for the extinction of condi
87 ion (qPCR) were employed to assess Ddr1/DDR1 messenger RNA expression in mouse and human tissues.
88 also report that circulating SQSTM1 and the messenger RNA expression levels of SQSTM1 and INSR in pe
92 are independent of changes in cognate linear messenger RNA expression or estimated brain cell-type pr
94 er permeability, with altered tight-junction messenger RNA expression, increased brain levels of infl
98 In addition, RD2 influences the abundance of messenger RNAs from >100 core chromosomal GAS genes.
101 was assessed for its ability to semiquantify messenger RNA immune-related markers directly from blood
102 r genome atlas for levels of KDM3A and DCLK1 messenger RNA in human pancreatic ductal adenocarcinoma
104 ales had more OT-immunoreactive cells and OT messenger RNA in the paraventricular nucleus of the hypo
107 t IFIT2 binds directly to viral and cellular messenger RNAs in AU-rich regions, with bound cellular t
108 ured goblet cell density and levels of Notch messenger RNAs in BE tissues from 164 patients, with and
111 fication of the levels of proteins and their messenger RNAs in single cells suggests that translation
112 terspersed element RNAs, noncoding RNAs, and messenger RNAs in trans Some L1-mediated retrotransposit
114 P), which translationally represses specific messenger RNAs, including the PI3K catalytic isoform p11
116 ng exogenous nucleic acids, especially large messenger RNAs, into cell-secreted exosomes leads to low
117 sensitizes neurons to glutamate by targeting messenger RNAs involved in glutamate receptor signalling
121 bined single-cell combinatorial indexing and messenger RNA labeling (sci-fate), which uses combinator
123 a low ratio also had higher NAIP and PYCARD messenger RNA levels after lipopolysaccharide stimulatio
124 tipsychotic-exposed monkeys, we found higher messenger RNA levels for 1) most NF-kappaB family member
125 0% of the genes with significantly decreased messenger RNA levels in the mutant mouse cortex are invo
126 ls rapidly absorbed labeled fatty acids, and messenger RNA levels of Lgr5(+) stem cell markers (Lgr5,
127 imilar pattern of elevated NF-kappaB-related messenger RNA levels was seen in adult mice that receive
130 ly parallel reporter assays from a synthetic messenger RNA library composed of over one million 5' UT
133 ed QTL and correlated the abundance of cecal messenger RNA, luminal microflora, physiology, and behav
134 icroRNA can target many functionally related messenger RNAs making microRNAs powerful epigenetic regu
135 ome-wide mapping in ESCs reveals hundreds of messenger RNAs marked by 5hmC at sites characterized by
136 cation, contributing to different aspects of messenger RNA metabolism(5,6), is detectable on the majo
137 -separated droplets that organize and manage messenger RNA metabolism, cell signaling, biopolymer ass
139 ddress the regulation and functional role of messenger RNAs, microRNAs, long noncoding RNAs, and circ
140 nd 0.880 under the full transcript or mature messenger RNA models, respectively) compared to the stat
143 productively rearranged Igh allele, the Igh messenger RNA (mRNA) (IgHR) from a nonproductively rearr
144 ssing a codon optimized Rs-rbcLS operon, the messenger RNA (mRNA) abundance was ~25% of rbcL transcri
145 neous activation due to a global increase in messenger RNA (mRNA) abundance, which reduces the thresh
147 are extensively characterized, extracellular messenger RNA (mRNA) and long non-coding RNA (lncRNA) st
150 wild-type BRAF were shown to increase PD-L1 messenger RNA (mRNA) and protein expression that was att
151 ishes a latent infection, with low levels of messenger RNA (mRNA) and protein expression, evolved to
153 olymerase chain reaction (PCR) for detecting messenger RNA (mRNA) and quantitative PCR for HBoV1 geno
155 The posttranscriptional modification of messenger RNA (mRNA) and transfer RNA (tRNA) provides an
156 e is that ribosomes read the genetic code in messenger RNA (mRNA) as triplets of nucleotides in a sin
157 paced microRNA (miRNA) target sites within a messenger RNA (mRNA) can act cooperatively, leading to m
159 C7 extension of sarecycline extends into the messenger RNA (mRNA) channel to form a direct interactio
163 tion is autoregulated by feedback control of messenger RNA (mRNA) degradation via an unknown mechanis
165 port preclinical studies evaluating systemic messenger RNA (mRNA) encoding human alpha-Gal A in wild-
168 ffects of GC exposure during neurogenesis on messenger RNA (mRNA) expression and DNA methylation (DNA
169 luated morphometric, immunohistochemical and messenger RNA (mRNA) expression changes in coeliac disea
170 ic region of chromosome 2p with no impact in messenger RNA (mRNA) expression was more common in RB (2
173 receptor-gamma coactivator-alpha (PPARGC1A) messenger RNA (mRNA) in skin fibroblast cultures from th
174 (6)A) regulates stability and translation of messenger RNA (mRNA) in various biological processes.
175 sense-mediated knockdown of endogenous ssbp1 messenger RNA (mRNA) in zebrafish resulted in compromise
176 CUG triplet located in the 5' leader of POLG messenger RNA (mRNA) initiates almost as efficiently (~6
177 vement of RNA polymerase (RNAP)-synthesizing messenger RNA (mRNA) is coordinated with the movement of
180 Advances in the detection and mapping of messenger RNA (mRNA) N(6)-methyladenosine (m(6)A) and 5-
186 (m6A) can play important roles in regulating messenger RNA (mRNA) splicing, export, stability and tra
189 itiation factor 4F (eIF4F)] at the 5' end of messenger RNA (mRNA) to form the 48S initiation complex
191 f the enzymatic functions required for viral messenger RNA (mRNA) transcription and replication: RNA
192 , such as between microRNAs (miRNAs) and the messenger RNA (mRNA) transcripts they regulate, and ther
194 how that BCL11A is regulated at the level of messenger RNA (mRNA) translation during human hematopoie
195 IN1, and mLST8, forming CTORC2, and controls messenger RNA (mRNA) translation through phosphorylation
197 m children without liver disease (controls); messenger RNA (mRNA) was isolated, randomly assigned to
198 SCs that expressed increased levels of Atoh1 messenger RNA (mRNA), acquired a gene expression signatu
199 (HR) HPV DNA, HPV16/18 genotyping, HPV E6/E7 messenger RNA (mRNA), and p16/Ki-67 dual stain in a popu
200 givosiran had sustained reductions in ALAS1 messenger RNA (mRNA), delta aminolevulinic acid, and por
201 Regulation of enzymatic 5' decapping of messenger RNA (mRNA), which normally commits transcripts
207 roach to treat PA using a combination of two messenger RNAs (mRNAs) (dual mRNAs) encoding both human
208 l repertoire of erythroid miR-144/451 target messenger RNAs (mRNAs) and associated cellular pathways
209 taneously inhibits the translation of globin messenger RNAs (mRNAs) and selectively enhances the tran
210 ve been shown to suppress the translation of messenger RNAs (mRNAs) by directing the RNA-induced sile
211 g RNAs that modulate the translation-rate of messenger RNAs (mRNAs) by directing the RNA-induced sile
213 onal gene regulation, and they interact with messenger RNAs (mRNAs) either by degradation or by trans
219 nducted massively parallel screens targeting messenger RNAs (mRNAs) of a green fluorescent protein tr
221 tory molecules that act by binding to target messenger RNAs (mRNAs) to reduce protein synthesis and h
222 binding to dozens of small RNAs (sRNAs) and messenger RNAs (mRNAs) to regulate mRNA-expression level
223 sed proteins are coupled with their encoding messenger RNAs (mRNAs) via a high-affinity stem-loop RNA
225 366 long noncoding RNAs (lncRNAs), and 3266 messenger RNAs (mRNAs) were differentially expressed (DE
228 LY proteins function together to export many messenger RNAs (mRNAs), but we found that ALY1 is unique
229 h noncoding RNAs (ncRNAs) and protein-coding messenger RNAs (mRNAs), degrading ncRNAs that fail to fo
230 cluding changing the translation of specific messenger RNAs (mRNAs), provide a rapid means to respond
234 leotide, thereby increasing the chances of a messenger RNA of being capped during mRNA maturation, wh
235 <= 0.001) and significant downregulation in messenger RNA of shared targets superoxide dismutase 2 (
236 , the BCR-ABL1 fusion gene and its companion messenger RNA offers a unique target differentiating can
237 st TRDs is the presence of toxicity from the messenger RNA or protein encoded by the gene harboring t
238 se in level of interleukin (IL) 1beta (IL1B) messenger RNA (P for comparison = .005), increased IL1B
239 2.69-fold increase in the expression of TNF messenger RNA (P for comparison = 0.013) compared with c
240 e spliceosome-catalyzed process by which pre-messenger RNA (pre-mRNA) is processed to mature mRNA, is
243 nizes the 3'-splice site (3'SS) of precursor messenger RNA (pre-mRNA) through non-Watson-Crick pairin
245 zoan replication-dependent histone precursor messenger RNAs (pre-mRNAs) contains the U7 small nuclear
247 nally, in situ hybridization showed that DMD messenger RNA primarily localizes in the nuclear compart
249 ol essential biological functions, including messenger RNA processing, cell signalling and embryogene
251 ted and analyzed by histologic, metabolomic, messenger RNA quantification, and RNA-sequencing analyse
252 were measured for protein (Western blot) and messenger RNA (quantitative reverse transcriptase polyme
254 tion, stability, or localization of maternal messenger RNAs required for patterning decisions before
255 am of terminators to block nuclear export of messenger RNAs resulting from RNA polymerase readthrough
256 e until they bind RNA aptamers inserted into messenger RNAs, resulting in fluorescent RNA-protein com
257 ethyltransferase identification (DamID) with messenger RNA sequencing of the same cell (scDam&T-seq).
259 -connectivity mapping data sets queried with messenger RNA signature of RUNX1 knockdown identified no
262 etes larger amounts of GGT, and a rifampicin messenger RNA stability study showed that one reason for
265 roles in the stress response(1,2), maternal messenger RNA storage(3), synaptic plasticity(4), tumour
266 plexes recognized by ADARs as readout of pre-messenger RNA structures, we reveal distinct higher-orde
267 in (Sur) biomarkers: the Sur protein and its messenger RNA (Sur mRNA), including immunosensors, elect
269 was found to robustly activate the transfer-messenger RNA system, even when transcription was inhibi
272 ntified a 3' untranslated region in the TP53 messenger RNA that bound miR675-5p; binding resulted in
274 rent motifs in the 3' untranslated region of messenger RNAs that were sex differentially translated.
275 main, canonical protein encoded on the same messenger RNA, thereby revealing the use of functional b
277 cation of reference genes 16S rRNA, transfer-messenger RNA (tmRNA), pre-16S rRNA, and rpoB by reverse
279 associated with a relative deficiency of GLS messenger RNA transcribed from the expanded allele, whic
281 cts the efficiency with which individual pre-messenger RNA transcripts are productively processed acr
282 pathogenesis of PH via the direct binding to messenger RNA transcripts for degradation or inhibition
284 A common assumption in studies of local messenger RNA translation is that the anti-puromycin sta
285 hich could then result in increasing the GSN messenger RNA translation via reduced miR binding to its
286 clear factor kappaB, and reduces oncoprotein messenger RNA translation, is a potential novel treatmen
287 icroRNA-377 precursor, which represses Vegfa messenger RNA translation, is druggable in a selective m
288 in RNA in situ hybridization to detect HHV-6 messenger RNA (U41 and U57 transcripts) in lung tissue.
289 e a foundation from which to optimize future messenger RNA vaccination studies against NiV and other
290 of a lipid nanoparticle nucleoside-modified messenger RNA vaccine encoding the soluble Hendra virus
292 se 1, dose-escalation, open-label trial of a messenger RNA vaccine, mRNA-1273, which encodes the stab
295 ed HIV DNA, unspliced HIV RNA, and chemokine messenger RNA were quantified by quantitative polymerase
297 e whole DRG transcriptome and 66 genes whose messenger RNAs were sex differentially actively translat
299 receptor (IR) have a 50% reduction in Arrdc3 messenger RNA, while, conversely, mice with liver-specif