ライフサイエンスコーパス: meta position

1 strates, can selectively be borylated at the meta position.

2 e-containing aromatic molecules at the arene meta position.

3 matics provided they had donor groups in the meta position.

4 ively the product of activation at the arene meta position.

5 ylbenzoic ester (the anchoring group) in the meta position.

6 ety for one of the isopropyl arms but in the meta position.

7 lation with a high selectivity for the arene meta position.

8 higher than the BDE of phenyl radical at the meta position.

9 ic rings possessing substituents at the para/meta position.

10 nzene bridge via alkyne spacers at para- and meta-positions.

11 yl or 2,4,6-triisopropylphenyl groups at the meta-positions.

12 logues are selectively functionalized at the meta-positions.

13 liodonium salt is selective for the pyridine meta-position, affording a regiodivergent approach to py

14 Notably, the substituent groups on the meta-positions alter both the geometric and the electron

15 nd CYP2B6 oxidized PCB 91 and PCB 132 in the meta position and that CYP2A6 oxidized PCB 95 and PCB 13

16 the aromatic carboxyl group in PT523 to the meta position and was further diminished by moving it to

17 earing methoxy or fluoro substituents in the meta position are generated from lithium diisopropylamid

18 th strong pi electron-donating groups in the meta positions are predicted to have low-energy or groun

19 n an electron-donating amino group is at the meta position, as demonstrated in our recent work of usi

20 l for relaying the palladium catalyst to the meta position by norbornene after initial ortho-C-H acti

21 protio-DBB the installation of groups at the meta positions decreases the optical band gap while para

22 TM) radical dimer covalently tethered at the meta position, demonstrating the feasibility of alternan

23 ic preference for C-H bond activation at the meta-position despite cobalt-aryl complexes resulting fr

24 he carboxy group at the para rather than the meta position, displayed 2200-fold selectivity against t

25 general, single substitutions at the para or meta position enhanced binding.

26 olution the chiral auxiliaries placed at the meta position exhibit very little influence during the c

27 that the substitution of aminomethyl at the meta-position greatly enhances inactivation of alkyltran

28 ifted from the para position in DB921 to the meta position, has also been examined by X-ray crystallo

29 nthrene, pyrene, and corannulene moieties in meta positions have been synthesized in a straightforwar

30 Substitution of a sulfonamide group at the meta position, however, produces compounds with excellen

31 precursors are methylated exclusively at the meta-positions (i.e. 3/5-OH) of their phenyl rings by na

32 tions in electron-rich substrates and at the meta position in electron-deficient molecules.

33 Moving the fluorines from the meta positions in 18 to the ortho positions in 20 revers

34 when bonded at ortho and para as compared to meta positions in the phenyl ring.

35 awing substituents in their para, ortho, and meta positions in THF at room temperature.

36 Additional steric bulk on amines or at meta positions increase or have neutral effect on affini

37 e conjugate addition to form a C-C bond at a meta position instead of the ipso-carboxyl position.

38 tion intermediate and is then relayed to the meta position, leading to meta-selective C-H arylation o

39 ara-para positions (para series 1-5) or meta-meta positions (meta series 6-10).

40 of TyrOH is found to be hydroxylated in the meta position, most likely through an autocatalytic proc

41 ules are stable zwitterions by virtue of the meta positions occupied by the nitrogen and oxygen subst

42 Selective functionalization at the meta position of arenes remains a significant challenge.

43 up on ring A and a hydrophobic moiety at the meta position of ring B.

44 pyridyl rings, respectively, attached at the meta position of the 5-phenyl ring.

45 Substituents at the meta position of the arene (H, OMe, F) and the dialkylam

46 carbamoyl moiety and the substituents in the meta position of the arene.

47 on the aryloxazoline and substituents at the meta position of the arenes (methoxy, oxazolinyl, and fl

48 effects of the substituents attached to the meta position of the aromatic ring.

49 mple, alpha-methyl benzylamine placed at the meta position of the benzoyl group (via an amide bond) y

50 Electron-withdrawing substituents at the meta position of the C(6) aryl group afforded substantia

51 Substitution of a sulfonamide at the meta position of the phenyl ring dramatically increases

52 4,5,6'-pentachlorobiphenyl (PCB 102), in the meta position of the symmetrically substituted phenyl ri

53 echlorination was predominantly from flanked meta positions of 34-, 234-, 235-, 236-, 245-, 2345-, 23

54 carboximide) (NI) acceptor are linked to the meta positions of a phenyl spacer to yield 5ANI-Ph-NI an

55 Amino-, hydroxy-, and thiol-groups in the meta positions of C-phenylnitrile imine lower the activa

56 forts identified the para and methoxy-distal meta positions of dMMO2 as particularly promising for fu

57 ed that phenols having two hydroxy groups at meta positions of the aromatic ring were the most effici

58 turing a monofluoro substitution at para and meta positions of the benzyl ring, respectively.

59 derivatives that contain steric bulk in the meta positions of the N-bound aryl rings (catalysts 3-5)

60 rigid amido (-CO-NH-) linkers to the para or meta positions of the pargyline phenyl ring, respectivel

61 ications were made at two locations: (1) the meta positions of the two aromatic rings and (2) the end

62 The incorporation of a methyl group at the meta-position of 1 (relative to 1') significantly improv

63 icient means of selectively substituting the meta-position of anilines to produce aromatic phosphoniu

64 tion platform for selective nitration at the meta-position of azines via a radical pathway.

65 nding characteristics of substituents in the meta-position of the aromatic ring may be important in m

66 ied that electronegative atoms placed at the meta-position of the B-ring exhibit improved cytoprotect

67 o[4,5-e][1,4]diazepin-5-one framework to the meta-position of the phenyl ring of the 3-methylamino-1-

68 gen-bonding oxime and pyrazole groups at the meta-position of the phenyl ring on the P2/P2' substitue

69 cally useful site-selectivities favoring the meta-position of the ring were observed.

70 enyl)methyl (TTM) radicals connected via the meta-positions of a phenyl linker.

71 lglycine ligands carrying TIPS-groups at the meta-positions of the aromatic ring exhibit outstanding

72 ent were the compounds with a halogen in the meta position on the aromatic ring of the benzyloxy- or

73 C(PEP)P the four anchoring groups are in the meta position on the meso-phenyl rings of the porphyrin

74 aining a bromine atom at either the ortho or meta position on the phenyl ring, such as 2BP-TQS (4-(2-

75 n bond-donating substituents at the para and meta positions on the phenyl ring.

76 Substituting the meta positions on these species with pi donors stabilize

77 Placement of a hydrogen-bond donor in the meta-position on the 6-arylmethyl group resulted in appr

78 complex suggested that an extension from the meta-position on the phenyl group (ring-5) would improve

79 ting the 2-phenyl group with halogens in the meta position or by replacing the phenyl ring with a 2-

80 ted previously to hydroxylate toluene at the meta position, producing primarily m-cresol.

81 ind that if the substituted nitrogen is in a meta position relative to both acetylene linkers, the da

82 es containing alkenyl groups tethered at the meta position relative to the imine directing group has

83 es containing alkenyl groups tethered at the meta position relative to the imine directing group has

84 hydrogen bond donor from the "ortho" to the "meta" position, relative to the pyridazine ring.

85 However, an amino group at the meta position results in a PPG with better overall chemi

86 Mono- or difluoro substitution at meta position(s), as in 22c and 22h, was advantageous fo

87 At the closer meta-position, smaller groups were stabilizing and large

88 ng the specificity and significance of the 2-meta position substituent.

89 ryloxypropyl)-1H-imidazoles, which possess a meta-positioned substituent in the aryl ring, have been

90 installing a second aurophilic group at the meta position that, however, does not in itself contribu

91 kylation of the Ph-substituent at ortho- and meta-positions, that leads to a 1,2,7,8,9,10-hexahydro-6

92 d (13)C nucleus and the hydrogen atom at the meta-position to record two-dimensional (1)H-(13)C(F) co

93 between redox sites attached in para- or in meta-positions to a central benzene bridge, we investiga

94 the para hydroxyl group altered to be at the meta position, together with the replacement of one benz

95 ectivity could be switched from the ortho to meta position, under identical conditions, by just chang

96 methoxy groups in one of the phenyl rings at meta positions, was prepared.

97 mide with cyclooctylamino substituent at the meta position, we designed and synthesized di-meta-subst

98 hand side of the molecule substituted at the meta position with a benzoic acid or a pyridyl carboxyla

99 repins (DBBs) functionalized at the para and meta position with respect to the boron center in order

100 is tethered to the C-3' phenyl at ortho and meta positions with different length linkers.

101 he optimal position for substitution was the meta-position with selected members approaching or excee

102 elective functionalization at both ortho and meta positions within arenes bearing N-based directing g