ライフサイエンスコーパス: metabolic enzyme

1 for additional modulators of this important metabolic enzyme.

2 s both the activity and stability of a major metabolic enzyme.

3 pS) is a universally conserved and essential metabolic enzyme.

4 f microbial physiology via manipulation of a metabolic enzyme.

5 to understand the emerging biology of these metabolic enzymes.

6 biotic chemistry and the nature of the first metabolic enzymes.

7 acting as a rhythmic acetyl-transferase for metabolic enzymes.

8 d C-termini and by shielding components from metabolic enzymes.

9 and was associated with changes in polyamine metabolic enzymes.

10 e limited by the cell's capacity to maintain metabolic enzymes.

11 imal polyanionic surfaces on a set of common metabolic enzymes.

12 interactions for genes of key regulatory and metabolic enzymes.

13 factor for ATP, nucleic acids, and countless metabolic enzymes.

14 electrophoresis to characterize nucleic acid metabolic enzymes.

15 red by altered abundance and activity of the metabolic enzymes.

16 cerevisiae purged of its endogenous glycogen-metabolic enzymes.

17 olecules, signaling proteins and a subset of metabolic enzymes.

18 e resulted from the incorporation of primary metabolic enzymes.

19 criptional activation and phosphorylation of metabolic enzymes.

20 -phosphate) is an essential cofactor of many metabolic enzymes.

21 l mRNA expression levels of arachidonic acid metabolic enzymes.

22 magnetic beads provided a broad spectrum of metabolic enzymes.

23 enough to damage a growing list of essential metabolic enzymes.

24 (100-fold) up-regulation in dimethyl sulfide metabolic enzymes.

25 ing PAF levels through modulation of the PAF metabolic enzymes.

26 de novo with targeted mutations in critical metabolic enzymes.

27 to physically or functionally interact with metabolic enzymes.

28 ns, elastase, lysozyme, myeloperoxidase, and metabolic enzymes.

29 press all of the known endocannabinoid (eCB) metabolic enzymes.

30 he cytochrome P450 (cyt P450) superfamily of metabolic enzymes.

31 r (Moco), which serves as a redox center for metabolic enzymes.

32 ng patient response to therapies that target metabolic enzymes.

33 RNA synthetases) and moderate preference for metabolic enzymes.

34 interactions of protein-folding factors and metabolic enzymes.

35 toskeletal polymers, chaperones, and various metabolic enzymes.

36 n factors, structural proteins, kinases, and metabolic enzymes.

37 els and regulation of phosphorylation of key metabolic enzymes.

38 known whether there is direct regulation of metabolic enzymes.

39 facilitate their intracellular transport to metabolic enzymes.

40 al groups: Components of immune response and metabolic enzymes.

41 a nutrient-rich environment after removal of metabolic enzymes.

42 tarch synthesis and on genes encoding starch metabolic enzymes.

43 n and sequence characterization of important metabolic enzymes.

44 taenoic acid (EPA) using the same downstream metabolic enzymes.

45 l of the 5- phosphate of the guide strand by metabolic enzymes.

46 Here we show that the metabolic enzyme acetyl-CoA synthetase 2 (ACSS2) directl

47 motaxis histidine kinase CheAY2, the central metabolic enzyme aconitase (AcnB) and the detoxifying en

48 e we compare messenger RNA profiles of 1,454 metabolic enzymes across 1,981 tumours spanning 19 cance

49 Our results revealed similar metabolic enzyme activities and metabolic clearance rate

50 te sensing coupled to feedback regulation of metabolic enzyme activity or expression.

51 ple exposure group (7.5%) indicated elevated metabolic enzyme activity, likely through the aryl hydro

52 When the challenge is the loss of a metabolic enzyme, adaptive responses can also shed signi

53 ency, but rather to dysfunction in the lipid metabolic enzyme AGMO, which is expressed in the epiderm

54 We show here that the metabolic enzyme alkylglyceronephosphate synthase (AGPS)

55 termination of the enzymatic activity of key metabolic enzymes allowed us to shed some light on the b

56 tracing biocatalytic mechanisms operating in metabolic enzymes along a phylogenetic timeline of the f

57 Zone-dependent differences in expression of metabolic enzymes along the portocentral axis of the aci

58 ys, we found that pDC-MM interactions induce metabolic enzyme Alpha-Enolase (ENO1) in both pDCs and M

59 Other metabolic enzymes also assemble into filaments at low pH

60 ATP-citrate lyase (ACLY) is a central metabolic enzyme and catalyses the ATP-dependent convers

61 that introduces a methyl modification into a metabolic enzyme and whose activity can be modulated by

62 ell-specific transcriptional analysis of ABA metabolic enzymes and ABA-responsive promoters, have all

63 ann-like domains are present in a variety of metabolic enzymes and are capable of binding diverse lig

64 ograde transport of cytoskeleton components, metabolic enzymes and axonal regeneration enhancers, was

65 ntributors to modified kinetic parameters of metabolic enzymes and candidates for further study.

66 RNAs result in a switch in the expression of metabolic enzymes and cause the acquisition of glucose-i

67 creening of compounds targeting cellular DNA metabolic enzymes and chromatin remodelers for their abi

68 rious effect of 2-aminoacrylate generated by metabolic enzymes and emphasizes the need for RidA to qu

69 e regulation of quorum sensing and secondary metabolic enzymes and encodes new pteridine metabolites

70 matic promiscuity and recruitment of primary metabolic enzymes and examples of genomic clustering of

71 SPR/Cas9 functional genomic screen targeting metabolic enzymes and identified PDXK-an enzyme that pro

72 reveal MYC effects on the translation of key metabolic enzymes and immune receptors in lymphoma cells

73 activated a focused gene network enriched in metabolic enzymes and implantation factors.

74 rx provides reducing equivalents for central metabolic enzymes and is implicated in redox regulation

75 ow that oncogenes directly regulate critical metabolic enzymes and metabolic signaling pathways.

76 ell subsets, describe the emerging roles for metabolic enzymes and metabolites in the control of immu

77 ell known as a cofactor for numerous central metabolic enzymes and more recently for playing a role i

78 ples that illustrate the regulation of plant metabolic enzymes and pathways by PTMs and their cross t

79 ion of a large network of cytoprotective and metabolic enzymes and proteins.

80 egulates mitochondrial function by targeting metabolic enzymes and proteins.

81 signaling to 144 proteins, among which were metabolic enzymes and regulators.

82 tumour suppression, few connections between metabolic enzymes and senescence have been established.

83 Their acyl-CoA products regulate metabolic enzymes and signaling pathways, become oxidize

84 e the associations between the expression of metabolic enzymes and the levels of the metabolites part

85 s showed that HBc promoted the expression of metabolic enzymes and the secretion of metabolites in HC

86 Vice versa, metabolic enzymes and their products also exert multilev

87 d protein kinase and mTOR, and also numerous metabolic enzymes and their respective regulators.

88 GABAergic machinery with expression of GABA metabolic enzymes and transporters, GABA-A receptors and

89 We profiled an additional set of relevant metabolic enzymes and transporters, including Crc target

90 rofile by restoring the level of fatty acids metabolic enzymes and use.

91 ent of zonal differences in the abundance of metabolic enzymes and, much more important, an estimatio

92 In this new array, films of DNA, metabolic enzymes, and an ECL metallopolymer or complex

93 nt levels: by modulating the activity of key metabolic enzymes, and by massive transcriptional reprog

94 target not only GPCRs but also transporters, metabolic enzymes, and chaperones.

95 mitting ruthenium metallopolymer, microsomal metabolic enzymes, and DNA to detect potential genotoxic

96 affects the localization and activity of key metabolic enzymes, and it may work antagonistically or c

97 mitochondrial respiratory chain proteins and metabolic enzymes, and knockdown of ClpP in leukemic cel

98 A theme is emerging wherein nutrients, metabolic enzymes, and metabolites can act as an extensi

99 al and altering expression of neuropeptides, metabolic enzymes, and other non-neural genes.

100 ex panel of 15 other metabolites, associated metabolic enzymes, and phosphoproteins, the resultant da

101 protein-RNA complexes derived from viruses, metabolic enzymes, and ribosomes.

102 n transcriptional and epigenetic regulators, metabolic enzymes, and small GTPases.

103 fic predicted responses to the inhibition of metabolic enzymes, and successfully inferred the prognos

104 g., the transcription-translation machinery, metabolic enzymes, and the replisome.

105 Some existing chemotherapies target metabolic enzymes, and there is a resurgent interest in

106 Our finding that MTHFD1 and other metabolic enzymes are chromatin associated suggests a di

107 Metabolic enzymes are presumed regulators of this glycol

108 has transitioned to discoveries highlighting metabolic enzymes as loci-specific regulators of gene ex

109 zation of each anionic lipid and its related metabolic enzymes as starting points, we summarize their

110 function not only by regulating activity of metabolic enzymes, as previously reported, but also by r

111 Numerous metabolic enzymes assemble into filamentous structures,

112 onal enzymes between Archaea and Eukarya and metabolic enzymes between Bacteria and Eukarya.

113 rrel protein that likely derived from a core metabolic enzyme but evolved a new activity.

114 These include several metabolic enzymes but also a small number of proteins in

115 level p73 does not directly regulate serine metabolic enzymes, but transcriptionally controls a key

116 r results reveal the contribution of the key metabolic enzyme Caa1 to TORC1 activity in S. pombe.

117 metabolic processes, this study shows that a metabolic enzyme can act as a pattern recognition recept

118 informative associations between kinases and metabolic enzymes capable of predicting metabolic change

119 Aldehyde oxidase (AOX) is a metabolic enzyme catalyzing the oxidation of aldehyde an

120 irS affects the expression of genes encoding metabolic enzymes, cell-wall envelope proteins, efflux p

121 wly identified alterations in genes encoding metabolic enzymes, chromatin remodelers and a high propo

122 The activities of the metabolic enzymes citrate synthase (CS), malate dehydrog

123 hat TrmB functions alone to regulate central metabolic enzyme-coding genes but cooperates with variou

124 ctivation of Mtb's isocitrate lyases (ICLs), metabolic enzymes commonly assumed to be involved in rep

125 ions, they are good systems for studying how metabolic enzymes communicate via substrate channeling.

126 ipA is known to modify the E2 subunit of the metabolic enzyme complex pyruvate dehydrogenase (E2-PDH)

127 med SESAME (Serine-responsive SAM-containing Metabolic Enzyme complex), which contains serine metabol

128 C specimens have similar alterations in atRA metabolic enzymes, consistent with reduced colonic atRA.

129 e lymphoid cells (ILC2), but whether certain metabolic enzymes control disease outcome has not been a

130 rcinogenic bulky adducts that can arise when metabolic enzymes convert pro-carcinogens into a highly

131 The aldehyde dehydrogenase (ALDH) family of metabolic enzymes converts aldehydes to carboxylates.

132 ctivity between mouse and primate carotenoid metabolic enzymes could account for this species-specifi

133 lly reshapes the mutational landscape of the metabolic enzyme dihydrofolate reductase (DHFR).

134 eneral mechanism to inactivate and store key metabolic enzymes during a state of advanced cellular st

135 abolic proteins with that of typical zonated metabolic enzymes during liver maturation and after acut

136 e BRISC structure, ABRO1 binds SHMT2alpha, a metabolic enzyme enabling cancer growth in hypoxic envir

137 Overall, MCPs consist of metabolic enzymes encased within a protein shell, and th

138 We identified an unexpected role for the metabolic enzymes enolase and aldo-keto reductase as pos

139 Choking cancer via inhibition of metabolic enzymes essential for tumor but dispensable in

140 Genes encoding metabolic enzymes exhibited expression in metacyclics wi

141 etabolic phenotype or maladaptive changes in metabolic enzyme expression and regulation in the respon

142 No toxicity was seen regarding metabolic enzyme expression, glutathione, or histopathol

143 ed cardiac hypertrophy and fibrosis, altered metabolic enzyme expression, increased cardiac transcrip

144 ghly heritable biomarker of CYP2A6, the main metabolic enzyme for nicotine, will also enable investig

145 pression, including glutaminase (GLS), a key metabolic enzyme for tumour proliferation.

146 arboxylesterases were identified as the main metabolic enzymes for hydroxamic acids.

147 ndrial lipids reach inner membrane-localized metabolic enzymes for phosphatidylethanolamine synthesis

148 toreversible two-component system CcaSR, two metabolic enzymes for production of the chromophore phyc

149 study identifies creatine kinases (CKs), key metabolic enzymes for rapid ATP generation via the phosp

150 rates proteasomes, ribosomes, chaperones and metabolic enzymes from non-membrane bound compartments.

151 ucosal sites through mechanisms dependent on metabolic enzyme function.

152 ssays, we discovered that a diverse range of metabolic enzymes function in heterochromatin regulation

153 m, which includes inhibiting key glutathione metabolic enzymes (GCLC and GPX1), as well as direct dep

154 n key transcription factors and their target metabolic enzyme genes can explain the decreases in asso

155 Fumarate hydratases (FHs) are essential metabolic enzymes grouped into two classes.

156 Although mutations in metabolic enzymes hardwire metabolism to tumourigenesis,

157 r-associated mutations in genes encoding key metabolic enzymes has provided a direct link between alt

158 The recent discovery of mutations in metabolic enzymes has rekindled interest in harnessing t

159 In particular, the catalytic activities of metabolic enzymes have been shown to be regulated by Lys

160 Recent work has found that many metabolic enzymes have the ability to polymerize in resp

161 tional modification that targets a number of metabolic enzymes; however, the mechanisms and downstrea

162 ons in the X-linked gene encoding the purine metabolic enzyme, hypoxanthine guanine phosphoribosyl tr

163 cohol dehydrogenase (AdhE) enzymes are a key metabolic enzyme in bacterial physiology and pathogenici

164 MTHFD2 is the most differentially expressed metabolic enzyme in cancer versus normal cells.

165 oncept that LAL in hepatocytes is a critical metabolic enzyme in controlling neutral lipid metabolism

166 lts support a concept that LAL is a critical metabolic enzyme in lung epithelial cells that regulates

167 Based on homozygous deletions affecting metabolic enzymes in 16 TCGA cancer studies and 972 canc

168 s and ROS level, plus down-regulation of Hcy metabolic enzymes in aortae from Ang II-infused rats wer

169 Sequential metabolic enzymes in glucose metabolism have long been h

170 hotspots in the IDH1 and IDH2 genes encoding metabolic enzymes in intrahepatic cholangiocarcinomas.

171 The differential expression of metabolic enzymes in noninvasive CL1-0 cells and invasiv

172 strating a functional collaboration of these metabolic enzymes in response to oxidative stress.

173 peutic approaches to control the activity of metabolic enzymes in T cell subsets represents a promisi

174 The ability to strategically inhibit key metabolic enzymes in the purine pathway unexpectedly byp

175 mitochondria during heartbeats to stimulate metabolic enzymes in the tricarboxylic acid (TCA) cycle

176 riptional upregulation and repression of key metabolic enzymes in this pathway.

177 variation acts in trans to regulate multiple metabolic enzymes in this pathway.

178 roliferation-independent instructive role of metabolic enzymes in tumor plasticity is still unclear.

179 In addition, RNAs encoding multiple metabolic enzymes, including enzymes sponsoring glycolys

180 and their metabolism is mediated by several metabolic enzymes, including fatty acid amide hydrolase

181 YAP/TAZ activation modulated metabolic enzymes, including glutaminase (GLS1), to coor

182 Mutations in metabolic enzymes, including isocitrate dehydrogenase 1

183 requires precise, coordinated action of DNA metabolic enzymes, including proteins responsible for DN

184 ion loops that control the expression of key metabolic enzymes, including the BR-inactivating enzymes

185 diated DNA repair, suggesting that targeting metabolic enzymes increases cancer cell susceptibility t

186 important for regulating motility, but also metabolic enzymes, indicating that TgCDPK3 controls proc

187 r findings suggest that the primary cause of metabolic enzyme inhibition is not the evolution of regu

188 the compounds in clementine juice provoking metabolic enzyme inhibition or induction.

189 osis knockouts to predict the impact of both metabolic enzyme inhibitors and metabolic pathways explo

190 g the relevance and utility of incorporating metabolic enzymes into in vitro bioassays.

191 phoserine phosphatase (PSP), a key essential metabolic enzyme involved in conversion of O-phospho-l-s

192 te:ferredoxin oxidoreductase (PFOR), a major metabolic enzyme involved in energy generation through o

193 Here, we identify metabolic enzymes involved in extracellular matrix remod

194 mes, proteases, G-protein-coupled receptors, metabolic enzymes, ion transporters, and proteins of unk

195 Self-assembly of metabolic enzymes is increasingly recognized as a genera

196 ntification of heterozygous mutations in the metabolic enzyme isocitrate dehydrogenase (IDH) in subse

197 Mutations in the metabolic enzymes isocitrate dehydrogenase 1 (IDH1) and

198 Mutations in the metabolic enzymes isocitrate dehydrogenase-1 (IDH1) and

199 increased glycolysis, changes in the use of metabolic enzyme isoforms, and increased secretion of la

200 The tryptophan metabolic enzyme kynureninase (KYNU) is mimicked by a po

201 egulatory responses, 3) quantified glutamate metabolic enzyme levels in the VMH, 4) examined astrocyt

202 monia and nitrite transport proteins and key metabolic enzymes mainly in the bottom large granules fa

203 III secretion effector protein (SteA), and a metabolic enzyme (malate dehydrogenase), and demonstrate

204 d with aberrant expression of genes encoding metabolic enzymes manifested as profound systemic metabo

205 died water and solute transport proteins and metabolic enzymes matched expectations from prior locali

206 Control of the G(1)-phase by a central metabolic enzyme may be a common mechanism of cellular r

207 tection on the protein synthesis machine and metabolic enzymes may dominantly contribute to the well

208 Inhibitors of HIF-1 or metabolic enzymes may impair the metabolic flexibility o

209 ulence factors that destroy host tissues and metabolic enzymes might play an important role in invasi

210 The activity of many proteins, including metabolic enzymes, molecular machines, and ion channels,

211 roposed that NOCT deadenylates and regulates metabolic enzyme mRNAs.

212 isruption or pharmacologic inhibition of the metabolic enzymes NAD kinase or ketohexokinase was growt

213 concept, we select the gastrointestinal drug metabolic enzyme NAT2 at 8p22, which is frequently lost

214 onged in a double heterozygous mutant of the metabolic enzyme non-quiescent mutant 1 (NQM1), a paralo

215 ure of the copper active site in the primary metabolic enzyme of these bacteria, particulate methane

216 lt, glomeruli showed increased expression of metabolic enzymes of central carbon metabolism, amino ac

217 compared the polar metabolites, lipids, and metabolic enzymes of resting splenic B cells purified fr

218 The genes coding for the core metabolic enzymes of the photorespiratory pathway that a

219 ensively analyzed the expression of the main metabolic enzymes of the polyamine pathway and spermine

220 Here we focus on two metabolic enzymes of the yeast S. cerevisiae, neutral tr

221 damide (AEA) and 2-arachidonoylglycerol, and metabolic enzymes of these ligands.

222 Protein complexes of sequential metabolic enzymes, often termed metabolons, may permit d

223 effects of small molecular inhibitors of DNA metabolic enzymes on cccDNA synthesis but avoids cytotox

224 rect regulation of nutrient transporters and metabolic enzymes or the control of transcription factor

225 to polymerize is well conserved for the few metabolic enzyme paralogs that have been studied in yeas

226 ing the question of whether other amino acid metabolic enzymes participate in chromatin regulation.

227 y to investigate the spatial organization of metabolic enzymes participating in glucose metabolism in

228 ethanotrophic bacteria because their primary metabolic enzyme, particulate methane monooxygenase (pMM

229 present a computational pipeline to identify metabolic enzymes, pathways, and gene clusters from a se

230 h a direct transcriptional regulation of the metabolic enzyme PFKFB3.

231 in which the protein kinase activity of the metabolic enzyme PGK1 plays an instrumental role and rev

232 proteasomal degradation of the rate-limiting metabolic enzyme phosphofructokinase (PFK).

233 It is well recognized that many metabolic enzymes play essential roles in cancer cells i

234 nderstanding the regulation and evolution of metabolic enzyme polymerization.

235 ized administration of RvE1 based on genetic/metabolic enzyme profiles.

236 report the crystal structure of the central metabolic enzyme pyridoxal kinase (PDXK), which catalyze

237 ved protein receptors, including the central metabolic enzyme pyruvate carboxylase (LmPC).

238 2017) identify reversible aggregation of the metabolic enzyme pyruvate kinase under environmental str

239 sphorylation-dependent regulation of the key metabolic enzyme, pyruvate dehydrogenase.

240 Moreover, we show that the metabolic enzyme, pyruvate kinase muscle (PKM), interact

241 Here, we identify 17 metabolic enzymes recruited to yeast SGs in response to

242 aling networks of kinases, phosphatases, and metabolic enzymes regulate these processes.

243 erging evidence indicates that nonglycolytic metabolic enzymes regulating diverse pathways can assemb

244 tional regulation for the rhythmic gating of metabolic enzymes remains elusive.

245 e for Mannose phosphate isomerase (MPI) as a metabolic enzyme required to maintain Warburg metabolism

246 idoxal 5'-phosphate, which regulates two key metabolic enzymes required for acute myeloid leukemia (A

247 f-function and gain-of-function mutations of metabolic enzymes, respectively.

248 hosphoglycerate dehydrogenase (PHGDH) is the metabolic enzyme responsible for shunting the glycolytic

249 stablished, the role of miRNAs in regulating metabolic enzymes responsible for RA abundance during ax

250 Further analysis of 20 central-metabolic enzymes revealed six activities that were redu

251 We have found that 60 of the 440 yeast metabolic enzymes robustly form structures, including 10

252 vide evidence that PPIs, together with their metabolic enzymes SAC2-SAC5, are crucial for vacuolar tr

253 ts with the chromatin regulator SIN3 and the metabolic enzyme SAM-S, uncover a complex relationship b

254 bolic Enzyme complex), which contains serine metabolic enzymes, SAM (S-adenosylmethionine) synthetase

255 ation for understanding how mutations in the metabolic enzymes SDH, FH, and IDH can result in cancer

256 Regulatory proteins, metabolic enzymes, some myofibrillar and blood plasma pr

257 AT1 and, consequently, decreased that of the metabolic enzyme succinate dehydrogenase (SDH) in the tu

258 g loss of KDM3B, including downregulation of metabolic enzymes such as ARG2 and RDH11.

259 olite levels and messenger RNA expression of metabolic enzymes suggest the existence of extensive rep

260 similar in structure to cofactors in modern metabolic enzymes, suggesting a possible abiotic origin

261 nce in mice but does not relieve CCR of most metabolic enzymes, suggesting CcpA-independent CCR mecha

262 phosphoglycerate dehydrogenase (PHGDH), the metabolic enzyme that catalyses the reaction that divert

263 ing glutamate dehydrogenase (GDH), a 336-kDa metabolic enzyme that catalyzes the oxidative deaminatio

264 Here we report that PHGDH, the key metabolic enzyme that catalyzes the rate-limiting step o

265 chorismate mutase (CM), a well-characterized metabolic enzyme that catalyzes the rearrangement of cho

266 e selective inhibition of a highly conserved metabolic enzyme that contains identical active site res

267 Phosphoglucomutase 1 (PGM1) encodes the metabolic enzyme that interconverts glucose-6-P and gluc

268 nto the mutational landscape of an important metabolic enzyme that is highly conserved throughout euk

269 Nicotinamide N-methyltransferase (NNMT) is a metabolic enzyme that methylates nicotinamide (NAM) usin

270 Pyruvate kinase M2 (PKM2) is a metabolic enzyme that plays important roles in both proc

271 Transcription-related factors and metabolic enzymes that are expressed in all tissues have

272 In order to identify host cellular DNA metabolic enzymes that are involved in the biosynthesis

273 ehydrogenase 1 and 2 (IDH1 and IDH2) are key metabolic enzymes that are mutated in a variety of cance

274 Given that Tup1 and the metabolic enzymes that control PI(3,5)P2 are highly cons

275 ar cloning to insecticide targets and to the metabolic enzymes that degrade insecticides before they

276 nophosphate dehydrogenase (IMPDH) are purine metabolic enzymes that function maintaining the cellular

277 lation-independent interactions with various metabolic enzymes that orchestrate nitrogen flow, such a

278 Cytochrome P450 enzymes (P450s) are metabolic enzymes that process the majority of FDA-appro

279 hough mechanisms that include alterations in metabolic enzymes that regulate DNA methylation and hist

280 rogenases (MDH and LDH) are homologous, core metabolic enzymes that share a fold and catalytic mechan

281 nhanced the translation of mRNAs for several metabolic enzymes, thereby increasing glycolysis and oxi

282 ties to heat stress, providing evidence that metabolic enzyme thermostability is rate-limiting at sup

283 nfolding stress, and inactivation of crucial metabolic enzymes through S-allylmercapto modification o

284 Mapping the cellular distribution of metabolic enzymes thus identifies pathways for regulatin

285 From metabolic enzymes to cell surface receptors, connecting

286 e strongest associations is the tendency for metabolic enzymes to form dihedral complexes, which we s

287 tabolic pathways by coupling the turnover of metabolic enzymes to the levels of key metabolites.

288 includes eCB compounds and their associated metabolic enzymes, together with cannabinoid receptors,

289 variety of paths taken by duplicated primary metabolic enzymes toward integration into specialized me

290 ntaining H2O2-sensitive cysteines, including metabolic enzymes, transcription factors, and uncharacte

291 ogene family members, such as RAP2A, and the metabolic enzyme TYMS; and association of vasogenic edem

292 uld help dissect the roles of this important metabolic enzyme under different environmental and dieta

293 Several metabolic enzymes undergo reversible polymerization into

294 t cover (i) cytotoxicity; (ii) activation of metabolic enzymes via binding to the arylhydrocarbon rec

295 rafish harbor a full complement of cobalamin metabolic enzymes, we used genome editing to study the l

296 Most metabolic enzymes were soluble, although numerous pathwa

297 Magnetic beads coated with metabolic enzymes were used to make potentially reactive

298 an indirect promiscuous replacement of a key metabolic enzyme, which would have been extremely diffic

299 cts are synthesized in plants by specialized metabolic enzymes, which are often lineage-specific and

300 Bioinformatic analysis revealed that metabolic enzymes, which either utilize or generate acet