ライフサイエンスコーパス: metabolic flux analysis

1 mistry, cell imaging, mass spectrometry, and metabolic flux analysis.

2 emission tomography scan, metabolomics, and metabolic flux analysis.

3 the novel redHuman algorithm, along with 13C-metabolic flux analysis.

4 ly disjoint: Flux Balance Analysis and (13)C Metabolic Flux Analysis.

5 lux analysis and isotopically non-stationary metabolic flux analysis.

6 nce precludes the use of standard stationary metabolic flux analysis.

7 itrogen supply were further explored through metabolic flux analysis.

8 C-labeled metabolites is a powerful tool for metabolic flux analysis.

9 atography/tandem mass spectrometry for (13)C-metabolic flux analysis.

10 In a (13)C experiment for metabolic flux analysis ((13)C MFA), we examined isotope

11 Based on (13)C-metabolic flux analysis ((13)C-MFA) and RNA sequencing,

12 years have culminated in establishing (13)C-Metabolic Flux Analysis ((13)C-MFA) as a routine methodo

13 Measuring metabolic rates by (13)C-metabolic flux analysis ((13)C-MFA) is of central import

14 (13)C-Metabolic Flux Analysis ((13)C-MFA) is rapidly being rec

15 (13)C metabolic flux analysis ((13)C-MFA) is the predominant t

16 We used (13)C-fingerprinting, (13)C metabolic flux analysis ((13)C-MFA), and RNA-sequencing

17 luding flux balance analysis (FBA) and (13)C-metabolic flux analysis ((13)C-MFA), offer direct insigh

18 ethod are similar to those found through 13C Metabolic Flux Analysis (13C MFA) for central carbon met

19 13C Metabolic Flux Analysis (13C MFA) is considered to be th

20 Such data can be integrated using 13C Metabolic Flux Analysis (13C MFA) to provide quantitativ

21 ethod of measuring intracellular fluxes, 13C Metabolic Flux Analysis (13C MFA), uses the labeling pat

22 Measuring fluxes by 13C metabolic flux analysis (13C-MFA) has become a key activ

23 13C metabolic flux analysis (13C-MFA) has been widely used t

24 ng 74 reactions and 61 metabolites using 13C-Metabolic Flux Analysis (13C-MFA).

25 s through a technique called two-scale (13)C Metabolic Flux Analysis (2S-(13)C MFA).

26 in PPP/glycolysis ratios were determined via metabolic flux analysis after spiking (13)C1,2,3-glucose

27 Metabolic-flux analysis, along with acetyl CoA and lacta

28 levant metabolic pathways revealed by recent metabolic flux analysis and discuss the consequences of

29 otrophic, and heterotrophic conditions using metabolic flux analysis and isotopic tracers such as (2)

30 e package that can perform both steady-state metabolic flux analysis and isotopically non-stationary

31 crophages were assessed by RNA sequencing or metabolic flux analysis and liquid chromatography-tandem

32 Isotope-based methods are commonly used for metabolic flux analysis and metabolite quantification in

33 fore, there is a need to develop a "unified" metabolic flux analysis approach that could be similarly

34 This includes metabolic flux analysis approaches that utilize the rate

35 Recent advances in (13)C-metabolic flux analysis are now permitting highly precis

36 rovides valuable information for later (13)C metabolic flux analysis as indicated by a labeling exper

37 Metabolic flux analysis based on stable-isotope labeling

38 A metabolic flux analysis, based on isotopic data, suggest

39 re this technology is key is in the field of metabolic flux analysis because the resolution of these

40 Metabolic flux analysis by (13)C and (2)H MRS showed tha

41 with experimentally based flux maps from 13C metabolic flux analysis compared with a standard parsimo

42 re involved in mitochondrial metabolism, and metabolic flux analysis confirmed enhanced oxidative pho

43 n stationary phase, which is consistent with metabolic flux analysis data.

44 Metabolic flux analysis demonstrated that 90% of the con

45 g transients in cellular metabolism, dynamic metabolic flux analysis (DMFA), and dynamic flux balance

46 Metabolic flux analysis evolved as a powerful means for

47 sotopomer analysis has extended the reach of metabolic flux analysis from steady-state to highly dyna

48 ng genome-scale isotopic nonstationary (13)C-metabolic flux analysis given the labeling dynamics of 1

49 Isotope-assisted metabolic flux analysis (iMFA) is a powerful method to m

50 Here we used CRISPR/Cas9 gene editing and metabolic flux analysis in betaTC3 cells, a murine pancr

51 Using (13)C metabolic flux analysis in human RPE cells, we found tha

52 Using untargeted metabolomics and metabolic flux analysis in primary steroidogenic luteal

53 ition-induced quiescence, we conducted (13)C-metabolic flux analysis in proliferating (P) and quiesce

54 alidated through (13)C isotopic labeling and metabolic flux analysis in stored red blood cells.

55 on flow through the metabolic network ((13)C-metabolic flux analysis) in developing Alex embryos to b

56 Using real-time metabolic flux analysis, in the present study, we show t

57 Modeling and (13)C metabolic flux analysis indicate that oxygen limitation

58 Isotopically nonstationary metabolic flux analysis (INST-MFA) has been previously a

59 tudy, we employed isotopically nonstationary metabolic flux analysis (INST-MFA) to estimate R(L) and

60 opose ITOCSY as a practical NMR strategy for metabolic flux analysis, isotope dilution experiments, a

61 approach involving stable isotopes (such as metabolic flux analysis) may be better suited to provide

62 balance analysis (FBA) (in silico), and (ii) metabolic flux analysis (MFA) (in vivo).

63 n fluxes than experimentally measured by 13C-metabolic flux analysis (MFA) and the appearance of unre

64 s for stationary, nonstationary, and dynamic metabolic flux analysis (MFA) are numerous.

65 f model-predicted flux values with available Metabolic Flux Analysis (MFA) fluxes yielded predicted e

66 (1)(3)C metabolic flux analysis (MFA) has become the experimenta

67 Metabolic flux analysis (MFA) is a commonly used approac

68 Stable isotope-assisted metabolic flux analysis (MFA) is a powerful method to es

69 Metabolic flux analysis (MFA) is a valuable tool for qua

70 Metabolic flux analysis (MFA) is considered to be the go

71 Metabolic flux analysis (MFA) is highly relevant to unde

72 Methods of metabolic flux analysis (MFA) provide insights into the

73 (13)C metabolic flux analysis (MFA) provides a rigorous approa

74 Metabolic flux analysis (MFA) quantitatively determines

75 ondrial pyruvate transport, we applied (13)C metabolic flux analysis (MFA) to cells after transcripti

76 ngs, novel genome-scale models (GSMs), (13)C-metabolic flux analysis (MFA), and machine-learning appr

77 The gold standard method is model-based metabolic flux analysis (MFA), where fluxes are estimate

78 be measured directly but are estimated with metabolic flux analysis (MFA), which relies on the patte

79 tabolomics, label-free metabolic pathway and metabolic flux analysis might become possible when apply

80 We then developed a thermodynamic metabolic flux analysis model to investigate whether reg

81 ally validated by bioenergetic profiling and metabolic flux analysis of 13C-labeled substrates.

82 Thus, metabolic flux analysis of a given organism in a mixed c

83 y correlated with results from prior (1)(3)C metabolic flux analysis of B. napus developing embryos.

84 eling in cell wall precursors makes possible metabolic flux analysis of cell wall biosynthesis based

85 racterized mutants were now studied by (13)C metabolic flux analysis of cultured developing embryos b

86 Metabolic flux analysis of cultured podocytes using gene

87 Metabolic flux analysis of live cells using NMR enables

88 Previous in vivo isotope labeling and metabolic flux analysis of the benzenoid network in petu

89 A comparative metabolic flux analysis of wild-type and mutant strains

90 Metabolic flux analysis of yeast coexpressing FAD2 and F

91 In this study, we performed (13)C metabolic flux analysis on a panel of isogenic cell line

92 tope probing (protein-SIP) and peptide-based metabolic flux analysis (PMFA).

93 For (13)C-metabolic flux analysis, principles of isotopic steady s

94 13C-Based metabolic flux analysis provides valuable information ab

95 Subsequent (13)C-metabolic flux analysis revealed a 3-fold lower investme

96 Integrated lipid profiling and metabolic flux analysis revealed that cancer cells with

97 Metabolic flux analysis revealed this to be due to the p

98 Metabolic flux analysis reveals that flux through the pl

99 13C steady-state metabolic flux analysis showed that oxidation of acetyl-

100 with glycolytic inhibition, as confirmed by metabolic flux analysis showing a significant decrease i

101 n the past, as they are a central element of metabolic flux analysis, the distribution of kinetic con

102 lize one such approach, thermodynamics-based metabolic flux analysis (TMFA), to make genome-scale, qu

103 pplication of metabolic control analysis and metabolic flux analysis to a variety of systems.

104 Here, we used metabolic flux analysis to determine the effects of ligh

105 We used (2)H/(13)C metabolic flux analysis to quantify intermediary metabol

106 plus five Escherichia coli mutants, and used metabolic flux analysis to show that (2)H/(1)H fractiona

107 with brain cancer, coupled with quantitative metabolic flux analysis, to map the fates of glucose-der

108 elopment and application of a computer-aided metabolic flux analysis tool that enables the concurrent

109 We develop a novel method, metabolic flux analysis/unknown fragments, that extends

110 In particular, metabolic flux analysis uses mass isotopomers of metabol

111 pathways involved in hepatic lipoapoptosis, metabolic flux analysis using [U-(13)C(5)]glutamine as a

112 Metabolic flux analysis via a (13)C tracer experiment ha

113 Steady-state metabolic flux analysis was used to define the metabolic

114 Accordingly steady-state metabolic flux analysis was used to define the metabolic

115 To probe metabolic state of hepatocytes, metabolic flux analysis was used to obtain the metabolic

116 (Angptl4(iDeltaEC)), and transcriptomics and metabolic flux analysis, we demonstrate that ANGPTL4 is

117 ative transcriptomics, reverse genetics, and metabolic flux analysis, we discovered that transcriptio

118 Importantly, using metabolic flux analysis, we identified a metabolic signa

119 Using a reverse genetic approach and metabolic flux analysis, we provide evidence that the cy

120 Using metabolic flux analysis, we show that Hand1 expression c

121 e powerful and reliable methodology of (13)C-metabolic flux analysis, we show that the respiratory TC

122 -genome sequencing and high-resolution (13)C-metabolic flux analysis were performed on 10 adaptively

123 table isotope labeling and computer-assisted metabolic flux analysis were used to investigate the met

124 loss during metabolism, we also performed a metabolic flux analysis, which confirmed that the majori

125 vides a powerful new toolbox for (13)C-based metabolic flux analysis, which is an emerging strategy i

126 sure liquid chromatography-mass spectrometry metabolic flux analysis with redox and switch-tag proteo

127 otype of 3T1-L1 cells using RNAseq and (13)C metabolic flux analysis within a network spanning glycol