ライフサイエンスコーパス: metabolic reaction

1 mic groups are biased toward using different metabolic reactions.

2 osynthesis, gravity perception, and numerous metabolic reactions.

3 red as enzyme cofactors in a wide variety of metabolic reactions.

4 and in the control of enzyme activities and metabolic reactions.

5 factors and targets, and complex pathways of metabolic reactions.

6 Plant peroxisomal proteins catalyze key metabolic reactions.

7 in all kingdoms and involved in a variety of metabolic reactions.

8 sequester this energy-rich carbon source for metabolic reactions.

9 y removed from the broth, suggesting further metabolic reactions.

10 from NADPH to P450, which in turn catalyzes metabolic reactions.

11 athetic nervous system leads to a cascade of metabolic reactions.

12 n, is a one-carbon acceptor and donor in key metabolic reactions.

13 min, which is implicated in numerous crucial metabolic reactions.

14 deling systems such as protein complexes and metabolic reactions.

15 cal release, solubilization, and biochemical/metabolic reactions.

16 to predict an organism's viability from its metabolic reactions.

17 fections can cause cellular dysregulation of metabolic reactions.

18 source of chemiosmotic energy for primitive metabolic reactions.

19 s sustained by a variety of redox-controlled metabolic reactions.

20 ts central role in over one hundred cellular metabolic reactions.

21 the conditions of fast kinetics typical for metabolic reactions.

22 fatty acid beta-oxidation and other critical metabolic reactions.

23 in the human body that participates in many metabolic reactions.

24 number of species required to catalyze these metabolic reactions.

25 s in vivo limits studies to relatively fast metabolic reactions.

26 y proteins involved in electron transfer and metabolic reactions.

27 t as signalling molecules and substrates for metabolic reactions.

28 000 regulatory interactions controlling 1597 metabolic reactions.

29 uilibrium thermodynamics or for the study of metabolic reactions.

30 of substrates and catalyze 65% of the known metabolic reactions.

31 ession of the enzymes catalyzing the related metabolic reactions.

32 ing a broad repertoire of cell behaviors and metabolic reactions.

33 determining genes and the energy barrier for metabolic reactions.

34 derscoring its importance in a wide array of metabolic reactions.

35 a stoichiometric model that encompasses 679 metabolic reactions.

36 can affect the compartmental localization of metabolic reactions.

37 zymes associated with them catalyze adjacent metabolic reactions.

38 During metabolic reaction, absorption of leflunomide split into

39 termined enzyme structures that catalyse 361 metabolic reactions across 225 pathways to investigate m

40 enome scale modeling is identifying critical metabolic reactions across diverse human tissues.

41 the involvement of oxygen in many essential metabolic reactions, all living organisms have developed

42 The increasing number of interconnected metabolic reactions allows the development of in silico

43 tabolic products (375,809 compounds from one metabolic reaction and 10,583,901 from two reactions).

44 accharomyces cerevisiae, consisting of 1,175 metabolic reactions and 733 metabolites, has appeared.

45 44 open reading frames and consisted of 1020 metabolic reactions and 988 metabolites.

46 are ubiquitous organelles that house various metabolic reactions and are essential for human health(1

47 ential coenzyme NAD plays important roles in metabolic reactions and cell regulation in all organisms

48 Pickaxe predicts novel metabolic reactions and compounds, which can be used for

49 is located in organelle that house essential metabolic reactions and contains high reactive oxygen sp

50 uantitatively the extent to which individual metabolic reactions and enzymes can be bypassed.

51 for connecting metabolites to genes through metabolic reactions and enzymes that catalyze them.

52 We used (13)C or (15)N tracers to assess metabolic reactions and fluxes and real time quantitativ

53 6, consists of 806 genes associated with 667 metabolic reactions and includes a detailed representati

54 F) assumes an essential role in a variety of metabolic reactions and is critical for normal cellular

55 New studies of metabolic reactions and networks in embryos are making i

56 There was concordant clustering of certain metabolic reactions and putative virulence loci but not

57 players in incompletely characterized human metabolic reactions and reveal metabolic readouts inform

58 PPM metabolic reactions and stoichiometry were based on Chla

59 lar attention is paid to recently elucidated metabolic reactions and the genetic characterization of

60 osystem respiration based on the kinetics of metabolic reactions and the scaling of resource use by i

61 factor-target interactions regulating 3,300 metabolic reactions, and 1,905 KO phenotypes for E. coli

62 identify shifted metabolic functions, unique metabolic reactions, and changes in flux in metabolic re

63 ith network connectivity, irreversibility of metabolic reactions, and maximal flux capacities.

64 ch as toxic pathway intermediates, competing metabolic reactions, and slow reaction rates.

65 metabolic pathways and the presence of novel metabolic reactions are often determined by feeding isot

66 Since some metabolic reactions are only catalyzed in specific envir

67 and 54 pairs of enzymes whose corresponding metabolic reactions are predicted to be unconditionally

68 ioxide fixation is one of the most important metabolic reactions as it allows the capture of inorgani

69 This obviously simultaneously decelerates metabolic reactions as they operate closer to their ther

70 Metabolic reactions as well as cell biological processes

71 This includes the identification of specific metabolic reactions associated with isotopic variation a

72 rk presents a framework for studying altered metabolic reactions between patients with CD and control

73 y adenosine 5'-triphosphate (ATP), fuel many metabolic reactions, but less is known about the direct

74 l framework within which the organization of metabolic reactions can be analyzed and elucidated.

75 guided manual curation, we have compiled the metabolic reactions carried out by this proteome to form

76 stae morphology, bioenergetic functions, and metabolic reactions carried out in mitochondrial membran

77 Biotin is an essential cofactor for multiple metabolic reactions catalyzed by carboxylases.

78 Understanding how metabolic reactions, cell signaling, and developmental p

79 Thus, this HTCS functions as a metabolic reaction center, coupling nutrient sensing to

80 Peroxisomes compartmentalize certain metabolic reactions critical to plant and animal develop

81 The sets of individual metabolic reactions deriving these systemic conversions,

82 any of Nature's most proficient catalysts of metabolic reactions do not show a good fit for the enzym

83 With an accurate picture of the set of metabolic reactions encoded in a genome, it is now possi

84 ox state can be exploited to drive desirable metabolic reactions, even improving productivity and yie

85 atabases dealing with chemical compounds and metabolic reactions facilitates this research and now al

86 concentrations, and allosteric regulation to metabolic reaction fluxes.

87 minimal cut set (MCS) approach that predicts metabolic reactions for elimination to couple metabolite

88 of NAD(+), the biosynthesis of NADP(+), and metabolic reactions for the reduction and oxidation of N

89 nformatics have enabled the discovery of new metabolic reactions from overlooked microbial species an

90 ii) We reidentify metabolic reactions from three metabolic pathway referen

91 ocesses implemented via the orchestration of metabolic reactions, gene regulation, and environmental

92 framework for ABE fermentation that combines metabolic reactions, gene regulation, and environmental

93 Although the role of biotin in metabolic reactions has long been recognized, its influe

94 Whereas most metabolic reactions have low fluxes, the overall activit

95 mechanism underlying the gamma-GT-catalytic metabolic reaction in excessive alcohol consumption is a

96 nzyme that catalyzes an irreversible primary metabolic reaction in plants.Previous studies have used

97 atom should considerably suppress the major metabolic reaction in sirolimus, 39-O-demethylation.

98 d their predicted metabolic products via one metabolic reaction in the Evidence-based Metabolome Libr

99 analysis to estimate the flux through every metabolic reaction in the model both when glucosinolates

100 rine hydrolases that likely mediate critical metabolic reactions in asexual parasites and enable rati

101 ts have been valuable to monitor the flux of metabolic reactions in biological systems, which is cruc

102 ile catalysts that mediate a wide variety of metabolic reactions in eukaryotic cells, while also bein

103 edicting steady state rates - or fluxes - of metabolic reactions in genome-scale metabolic networks.

104 consist of a protein shell which sequesters metabolic reactions in its interior.

105 lar organelles that carry out numerous vital metabolic reactions in nearly all eukaryotes.

106 metabolic reactions, and changes in flux in metabolic reactions in response to these compounds.

107 Since metal ions are known to catalyze metabolic reactions in the absence of enzymes, here we e

108 centration of enzymes catalyzing the various metabolic reactions in the crowded cytoplasm.

109 needed for reducing equivalents generated by metabolic reactions in the cytosol to be oxidized via ae

110 Molybdenum-containing enzymes catalyze basic metabolic reactions in the nitrogen, sulfur, and carbon

111 hared tissue-specific or uniformly essential metabolic reactions in their metabolic networks.

112 ofluidic device for coupled phase I/phase II metabolic reactions in vitro.

113 ination of non-enzymatic organocatalytic and metabolic reactions in vivo for the sustainable synthesi

114 er activity, which is critical for important metabolic reactions, including diphthamide biosynthesis.

115 nt a relatively simple method for extracting metabolic reaction information from free text that score

116 Metabolic flux, or the rate of metabolic reactions, is one of the most fundamental metr

117 Through this, we identify metabolic reactions leading to putative phosphate source

118 Plant peroxisomes accommodate a multitude of metabolic reactions, many of which are related to the be

119 Metabolic reaction maps allow visualization of genome-sc

120 Using metabolic reaction maps of yeast, Arabidopsis, and human

121 taset in the context of functionally related metabolic reaction modules identified within the model v

122 econd, we determined the cytochrome-mediated metabolic reactions most typical for each group and exam

123 With the metabolic reaction network established, it becomes neces

124 c model of the yeast cell, based on its full metabolic reaction network extended with protein synthes

125 signature of BM composition was mapped as a metabolic reaction network highlighting interconnected b

126 A general metabolic reaction network model developed in this paper

127 flexible synthetic platform to study complex metabolic reaction networks and embodied chemical comput

128 of metabolomic and transcriptomic data into metabolic reaction networks identified condition-specifi

129 to fluorescence correlation spectroscopy and metabolic reaction networks.

130 were identified using mediation analyses and metabolic reaction networks.

131 tant water soluble vitamin (B2) required for metabolic reactions, normal cellular growth, differentia

132 ch Stt4/PI4KIIIalpha recruitment, and thus a metabolic reaction of fundamental importance in cell phy

133 ucuronic acid is the most important phase II metabolic reaction of steroidal compounds.

134 During oxygenic photosynthesis, metabolic reactions of CO2 fixation require more ATP tha

135 reaction fluxes can be utilized to determine metabolic reactions of high importance, amongst other an

136 However, the metabolic reactions of these species are underexplored,

137 This genotype contains 488 metabolic reactions operating on 343 metabolites.

138 rted into the cell but are not inputs to any metabolic reaction or pathway; and comparative analyses

139 Thus, we can now define systemic metabolic reactions, or eigen-reactions, for the study o

140 rted to active drugs in the body by enzymes, metabolic reactions, or through human-controlled actions

141 gmatis were deconvoluted with a genome-scale metabolic reaction-pair network to generate hypotheses a

142 ested that long-term HFD may affect specific metabolic reaction/pathways by altering enzyme activitie

143 orporates the full suite of genes, proteins, metabolic reactions, pigments, and biochemical compositi

144 In the presence of these varying metabolic reactions, PMNs (37 or 4 degreesC; +/- triacsi

145 a variety of proteins involved in important metabolic reactions, potentially including plastidic pat

146 Both cell lines exhibited distinct metabolic reaction profiles but shared elevated levels o

147 Living systems contain a vast network of metabolic reactions, providing a wealth of enzymes and c

148 le of inter-organelle contacts in organizing metabolic reactions remains poorly understood.

149 entalization may prevent competition between metabolic reactions requiring the same cofactor.

150 stance and be metabolically closely related; metabolic reaction sequences also follow smooth paths in

151 of redox-active enzymes involved in critical metabolic reactions, signaling pathways, and biological

152 ways appeared to be involved and resulted in metabolic reactions such as oxidation and reduction in a

153 al organelles that compartmentalize critical metabolic reactions, such as the breakdown of fats, in e

154 cally generating GENREs includes identifying metabolic reactions supported by sufficient genomic evid

155 Under these conditions, a metabolic reaction system can be reconceptualized in ter

156 Mitochondria carry out numerous metabolic reactions that are critical to cellular homeos

157 Peroxisomes house critical metabolic reactions that are essential for seedling deve

158 chemical moieties through the complex set of metabolic reactions that happen in the cell is essential

159 oli, 547 enzymes encoded by these genes, 702 metabolic reactions that occur in E.coli and the organiz

160 nes, 306 enzymes encoded by these genes, 580 metabolic reactions that occur in E.coli and the organiz

161 ymes encoded by a subset of these genes, 595 metabolic reactions that occur in E.coli, and the organi

162 ymes encoded by a subset of these genes, 904 metabolic reactions that occur in E.coli, and the organi

163 dation of sulfides to sulfoxides is a common metabolic reaction, the sulfides derived from brefeldin

164 ctional enzyme that can catalyze consecutive metabolic reactions, the aspartokinase I domain was fuse

165 To expand the targetable metabolic reactions, there is a demand for developing ex

166 est the coupling of cytoplasmic and vacuolar metabolic reactions through ASC-mediated redox activity.

167 atical models, MFA can quantify the rates of metabolic reactions through biochemical pathways.

168 , FDM) to quantify the contribution of every metabolic reaction to metabolic functions, e.g. the synt

169 t symbiont genomes and a complete mapping of metabolic reactions to an Escherichia coli in silico mod

170 at regulate vital biological functions, from metabolic reactions to expression modulation.

171 thermodynamic bottlenecks and enable diverse metabolic reactions to occur under the oligotrophic cond

172 Here we use four non-native metabolic reactions to rewire central carbon metabolism

173 Explainer searches the organism's network of metabolic reactions, transporters, cofactors, enzyme sub

174 on correlation coefficients is calculated, a metabolic reaction tree can be determined through the ap

175 ents, and the subsequent construction of the metabolic reaction tree is readily achievable for genome

176 ierarchically into sets of modules to form a metabolic reaction tree.

177 mmon, and iPY1537 and iJB1411 have 67 and 36 metabolic reactions unique to each, respectively.

178 hrough the resilencings of the non-essential metabolic reactions, using growth rate as selection prob

179 RA level is maintained through a cascade of metabolic reactions where retinal dehydrogenases (RALDHs

180 dinucleotide (FAD) is involved in important metabolic reactions where the biological function is int

181 Butanal and isoamyl acetate underwent metabolic reactions, which decreased their amount in the

182 e upregulation of proteins linked to several metabolic reactions, which produce TCA cycle intermediat

183 e two examples are chosen to illustrate that metabolic reactions with high control strength participa

184 of genes encoding a reaction, identified 102 metabolic reactions with significant change in flux in M

185 trongest driver of the net rates of cellular metabolic reactions, with metabolite concentrations coll

186 erential equations describing the individual metabolic reactions within the cardiomyocyte over time.