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1 sequencing DNA directly from an environment (metagenomics).
2 BRA bacterial community structure (V3V4 16 S metagenomics).
3 ed encephalitis was investigated using viral metagenomics.
4 resolvable in the near future through viral metagenomics.
5 one that we discuss here, is in genomics and metagenomics.
6 ress the problem of barcode deconvolution in metagenomics.
7 wo historical baboons from a zoo via shotgun metagenomics.
8 surface microbiome was assessed with shotgun metagenomics.
9 en using culture-independent high-throughput metagenomics.
10 sequencing data is a challenging problem in metagenomics.
11 obing, Raman-activated cell sorting and mini-metagenomics.
12 al gut virome in 44 recipients of HSCT using metagenomics.
13 ncing reads is one of the important goals in metagenomics.
14 approaches from other fields to the field of metagenomics.
15 ence genome, limiting the potential of whole metagenomics.
16 tance of detailed profiling methods, such as metagenomics.
17 biome alterations in ACLF using quantitative metagenomics.
18 s the increasing number of disciplines using metagenomics.
19 ture as evidenced by amplicon sequencing and metagenomics.
20 target-specific polymerase chain reaction or metagenomics.
23 plant virus families identified in fungi by metagenomics 91 Acknowledgements 91 References 91 SUMMAR
26 of DNA methylation information into shotgun metagenomics analyses will complement existing methods t
27 r Citrobacter rodentium infection along with metagenomics analyses, multicolor flow cytometry, and bi
28 pplications such as de novo genome assembly, metagenomics analysis and single nucleotide polymorphism
38 ed and fecal DNA was sequenced using shotgun metagenomics and analyzed with specifically designed bio
41 escence and electron microscopy, analyzed by metagenomics and cultured using previously developed met
43 microbial composition by performing shotgun metagenomics and de novo assembly of metagenome-assemble
52 ments using (15) N methylamine combined with metagenomics and metaproteomics facilitated identificati
54 Biomass was sampled from both reactors for metagenomics and metaproteomics, yielding a set of genom
55 tegrated approach using both virion-enriched metagenomics and metatranscriptomics constitutes a power
56 vealed that a combination of virion-enriched metagenomics and metatranscriptomics may be a more compr
57 s to acetate, CO2 , H2 and formate, combined metagenomics and metatranscriptomics show that unculture
59 iral communities revealed by virion-enriched metagenomics and metatranscriptomics were not interchang
60 tween pairs of coexisting gut microbes using metagenomics and microarray-based metatranscriptomics da
64 lyzing 16S rRNA microbial profiling, shotgun metagenomics and SCFAs in 153 fecal samples from non-kid
68 ve been used to study viral diversity, viral metagenomics and virus-host interactions in natural ecos
69 e-independent amplification (virion-enriched metagenomics) and metatranscriptomics based on bulk RNA
70 ; 285 fecal samples were analyzed by shotgun metagenomics, and 60 fecal samples were analyzed for met
71 and blood culture specimens, next-generation metagenomics, and gas chromatography mass spectrometry.
74 metagenomics resources, such as MG-RAST, EBI Metagenomics, and probeBASE, as well as a newly compiled
75 currently available virus genomes come from metagenomics, and some of these represent extremely abun
76 ducted a mesocosm experiment combined with a metagenomics approach (GeoChip 5.0) to elucidate the eff
77 dy of CBM_E1, which was discovered through a metagenomics approach and is the founding member of a no
78 wabs using an RNA sequencing (RNA-seq)-based metagenomics approach and Taxonomer, an ultrarapid, inte
79 WGA kits were tested for their utility in a metagenomics approach to identify the pathogens in sonic
85 iscuss how uHTS can inspire novel functional metagenomics approaches to identify natural biocatalysts
86 tions of targeted amplicon and shotgun-based metagenomics approaches to infectious disease diagnostic
87 polymerase chain reaction to high throughput metagenomics, appropriate resources for the analysis of
88 s review, we highlight the benefits of using metagenomics as well as the breadth of conclusions that
89 A high-throughput 16S V1-V2 rRNA gene-based metagenomics assay was developed and evaluated using >13
92 survey of a small agroecosystem using a new metagenomics-based approach involving rolling circle amp
95 per, we comprehensively assess approaches to metagenomics-based prediction tasks and for quantitative
102 genomics and subsequently as genome-resolved metagenomics, can circumvent this limitation by obtainin
104 from a joint hydrological, geochemical, and metagenomics characterization of a geothermal doublet in
105 is the first scalable, efficient, and rapid metagenomics classification algorithm capable of matchin
106 wrapping of a number of popular command-line metagenomics classification programs (Kraken, CLARK, DIA
107 datasets used to evaluate Kraken, a similar metagenomics classification tool, were used to measure a
108 quencing of known bacterial genomes within a metagenomics community, enriching the remaining species
111 Normalized viral read counts for untargeted metagenomics correlated with viral burden determined by
113 nomer, an ultrarapid, interactive, web-based metagenomics data analysis tool, with an FDA-cleared res
115 sical and biological approach, combined with metagenomics data and biotechnological advances, will en
117 ustrate how Keanu works by exploring shotgun metagenomics data from a sample collected from a bluff t
118 te this model with 16S rRNA gene and shotgun metagenomics data from defined bacterial communities.
120 f the main challenges when analyzing complex metagenomics data is the fact that large amounts of info
122 rapid, accurate, and interactive analyses of metagenomics data on personal computers and mobile devic
123 t in the data can be useful, especially with metagenomics data or data suspected to be contaminated.
124 ere, Roux and colleagues present time series metagenomics data revealing new virophage genera and the
125 enable timely and accurate analysis of large metagenomics data sets on conventional desktop computers
127 y genomics, transcriptomics, epigenomics and metagenomics data stored either locally or retrieved fro
128 describe an approach that combines existing metagenomics data with reverse genetics to engineer reag
129 address the main challenges of longitudinal metagenomics data, i.e. high-dimensionality, dependence
135 built on the combination of Tara with other metagenomics datasets, which results in 235 families wit
141 plore the application of these techniques to metagenomics, discuss their pros and cons, and speculate
142 red functional components were identified by metagenomics, enabling validation of robust in vivo RNA-
143 ructure and function modeling through marine metagenomics, especially for difficult proteins with few
146 rt highlights the utility and limitations of metagenomics for assessing public health risks regarding
147 nical laboratories are evaluating the use of metagenomics for identification of infectious agents dir
157 Over the past 2 years, MGnify (formerly EBI Metagenomics) has more than doubled the number of public
158 on exists, although single-cell genomics and metagenomics have alleviated some of this bottleneck.
160 ful culture-independent tools, in particular metagenomics, have substantially advanced virus discover
164 NGS methods using (i) unselected HCV RNA (metagenomics), (ii) preenrichment of HCV RNA by probe ca
165 man parvoviruses were recently discovered by metagenomics in Africa, bufavirus (BuV) in 2012 and tusa
167 xplore protocol optimization for leaderboard metagenomics in real samples, we introduce a benchmark o
169 bial life in hydrothermal deposits and their metagenomics-inferred physiology in light of the geologi
175 ir experimental identification by functional metagenomics is challenging, mainly due to the difficult
176 arly striking case of a virus discovered via metagenomics is crAssphage, which is by far the most abu
183 al challenge experiments, field surveys, and metagenomics, leading to the conclusion that a densoviru
185 statistical power of microfluidic-based mini-metagenomics make it a powerful tool to dissect the geno
188 rated analysis of multiomics data, including metagenomics, metatranscriptomics and metabolomics, with
193 al pipelines have been combined into shotgun metagenomics methods that have transformed microbiology.
194 ter Like for most viruses discovered through metagenomics, most of the basic biological questions abo
196 otal 730 patients were evaluated by targeted metagenomics (n = 573 patients), digital droplet PCR (n
199 e Darby Island, The Bahamas using predictive metagenomics of the 16S rRNA gene coupled with direct wh
200 ersity of MDV protists, we performed shotgun metagenomics on 18 sites representing a variety of lands
201 a mass ratio approach and conducted shotgun metagenomics on purified viral samples collected from a
202 ne amplicon sequencing, we performed shotgun metagenomics on the (13)C-labeled DNA to obtain function
211 rom isolate genomes, but culture-independent metagenomics provide a new window into their diversity.
214 es, including the Sequence Read Archive, the Metagenomics Rapid Annotation through Subsystems Technol
215 and development through our experience with metagenomics-RAST (MG-RAST), the most popular metagenomi
216 onomic and functional inference performed on metagenomics reads, no shift in structure and function o
219 This issue also includes updates on popular metagenomics resources, such as MG-RAST, EBI Metagenomic
220 plates on which to conduct culture-enriched metagenomics, resulting in the recovery of greater taxon
223 ing amino acid and protein biochemistry with metagenomics revealed that systematic purifying selectio
224 eting different biomolecules, including DNA (metagenomics), RNA (metatranscriptomics) and proteins (m
225 ncing data set to quantify distances between metagenomics samples from various human body habitats, N
233 d a combination of 16S rRNA gene sequencing, metagenomics sequencing, and mass spectrometry-based met
236 Microbial DNA was isolated, processed for metagenomics shotgun sequencing, and taxonomic and funct
239 recision, bias and robustness to a number of metagenomics-specific challenges were determined using a
242 Recently, some CE1 enzymes identified in metagenomics studies have been predicted to contain a fa
243 uencing technologies, an increased number of metagenomics studies have suggested the dysbiosis in mic
245 un based next-generation transcriptomics and metagenomics studies often generate 100-1000 GB sequence
250 e and ankylosing spondylitis, a quantitative metagenomics study based on deep shotgun sequencing was
251 lts from 16S rRNA gene amplicon analysis and metagenomics suggested that disturbances in the system w
259 lenging cases demonstrated the potential for metagenomics to advance existing methods for investigati
260 gene community analysis and genome-resolved metagenomics to characterize anaerobic wastewater treatm
261 trates the power of integrating DNA-SIP with metagenomics to characterize emerging organic contaminan
262 to assess cell structures and interactions; metagenomics to characterize enrichment taxa, generate m
264 we combined 16S rRNA sequencing and shotgun metagenomics to characterize the whole-organism microbio
267 ics, toxicology, metabonomics, genomics, and metagenomics to elucidate and validate the mechanism of
268 Furthermore, it demonstrates the power of metagenomics to glean large amounts of comparative data
269 ply paired metaproteomics and dsDNA-targeted metagenomics to identify 1,875 virion-associated protein
272 e isotope probing (SIP) with genome-resolved metagenomics to identify microorganisms associated with
275 ombine culture-based population genomics and metagenomics to investigate the within-microbiome evolut
277 g spatial variation in host tolerance, using metagenomics to quantify spatial variation in parasite p
280 ltures, we used single-filament genomics and metagenomics to retrieve draft genomes of 3 marine Candi
281 n of metatranscriptomics and genome-resolved metagenomics to study microbial activities in oil-contam
282 tiple assay technologies including genomics, metagenomics, transcriptomics, proteomics, and metabolom
285 tend the knowledge gained in human gut virus metagenomics (viromics) to disentangle the potential rol
288 about enzymatic chemistry into quantitative metagenomics, we determined the abundance and distributi
292 ives on in the age of microbial genomics and metagenomics, we propose an automated approach, employin
293 Archaea-specific quantitative (q) PCR and metagenomics were used to detect specific archaeal seque
294 technology has greatly promoted the field of metagenomics where previously unattainable information a
295 The situation is even more severe in shotgun metagenomics, where the contigs are often short, and the
296 s, Nubeam is ideal to analyze data sets from metagenomics whole genome shotgun (WGS) sequencing, wher
298 CDS platform is a robust tool for functional metagenomics, with the potential to significantly improv
300 specimens and 1/27 controls (P < .003), and metagenomics yielded archaea, mostly methanogens, in 28/