ライフサイエンスコーパス: methyl group

1 ds to the elimination of a proton from the 2-methyl group.

2 st likely be attributed to the exchange of a methyl group.

3 together but when they are separated by one methyl group.

4 tional ZF interacts with a conserved thymine methyl group.

5 s, in which one of the substituents is not a methyl group.

6 hobic interactions with the methylcytosine 5-methyl group.

7 vital interactions through its beta-branched methyl group.

8 e trifluoromethyl group in comparison to the methyl group.

9 a 4-fluorophenyl moiety substitutes for the methyl group.

10 substrates in which the olefin bears a beta-methyl group.

11 ety that include either a trifluoromethyl or methyl group.

12 lectronic effects of the fluorination at the methyl group.

13 ation is constrained by Val285 and the 5mCpG methyl group.

14 ure of ETX2514 was missing a double bond and methyl group.

15 erroneous assignment of the position of the methyl group.

16 ically different from that associated with a methyl group.

17 e biosynthesis, and the flux of folate-bound methyl groups.

18 central 1-carbon pathway for the transfer of methyl groups.

19 ntial propagation positions are blocked with methyl groups.

20 thyl group to mRNA while demethylases remove methyl groups.

21 tert-butyl substituents on the ligands with methyl groups.

22 m of transferring moieties other than simple methyl groups.

23 the C(sp(3))-H bonds of one of the prochiral methyl groups.

24 , resulting in the four spatially equivalent methyl groups.

25 ne interactions between the alpha- and gamma-methyl groups.

26 ffect favoring hydrogen abstraction from the methyl groups.

27 l toluene with all three H isotopes in their methyl groups.

28 sion of key genes to minimize loss of labile methyl groups.

29 ibly converted to betaine, a major source of methyl groups.

30 stallation of radioactive and stable labeled methyl groups.

31 tral lumen rendered by the interior-pointing methyl groups.

32 ty was observed in the presence of two alpha-methyl groups; (2) aliphatic carboxylic acids containing

33 studies showed the two subtypes with an N-1 methyl group (9 and 10) inhibited RNase H in low micromo

34 preclude Watson-Crick base pairing, the N(6)-methyl group alters the stability of RNA secondary struc

35 nt Ala-810 makes hydrophobic contacts with a methyl group and aniline in nintedanib and blocks water

36 tween any of the H atoms of the transferring methyl group and either Met40 or Asp141.

37 Subsequent introduction of the methyl group and functional group transformation complet

38 d that several genes encoding key enzymes of methyl group and polyamine metabolism, including Ornithi

39 e readily observed on substrates lacking a 5-methyl group and, remarkably, TET enzymes can be similar

40 /Abcb4), resulting in reduced consumption of methyl groups and biliary PC secretion.

41 lex regulatory feedback network between free methyl groups and genomic imprinting at birth.-Tserga, A

42 applicable for backbone amide and side chain methyl groups and represents a time and cost-effective a

43 choline-deficient (MCD) diet, which depletes methyl groups and results in a deleterious decrease in t

44 ance restraints from backbone amides and ILV methyl groups, and a 4.1 angstrom resolution EM map.

45 amine group of lysine can accept up to three methyl groups, and experiments show that protein-protein

46 tallation of metabolically robust deuterated methyl groups, and tandem ring formation, further demons

47 arent kinetic isotope effects related to the methyl group are more pronounced than for the methylene

48 ecules that lack an easily substituted (11)C-methyl group are often considered to have non-obvious st

49 Methyl groups are among the most prevalent structural el

50 These methyl groups are in van der Waals contact with a conser

51 he major groove side, and thus their pendant methyl groups are on the minor groove side.

52 Methyl groups are powerful probes for the analysis of st

53 Methyl groups are predominantly installed into biomolecu

54 hodology could expand the application of the methyl group as a useful protecting group.

55 ks on the Cu(110) surface by utilizing the 4-methyl groups as unique connection points.

56 ine-4-yl-methanethiol ligand due to an extra methyl group, as compared to a more rigid 4-pyridinethio

57 cence and excellent photostability, (b) an N-methyl group at each end of the squaraine core that ensu

58 An N-methyl group at position 33 blocks uncontrolled aggregat

59 ed that the placement of a single side chain methyl group at specific positions in a traptamer determ

60 4-(3 H)-ones (DABOs) by the intoduction of a methyl group at the alpha-benzylic position is known to

61 to metabolic stability, while positioning a methyl group at the C1 position of the P1' cyclopropyl r

62 Addition of a methyl group at the C10 position of the steroid has a si

63 hat results from the enzymatic addition of a methyl group at the fifth carbon of the cytosine base.

64 tivity, and that both the ester bond and the methyl group at the gamma-position of Thr4 are crucial f

65 Conversely, the introduction of a methyl group at the methylene hinge connecting the 6-ami

66 t C1 and C1' or lack the naturally occurring methyl group at those positions were synthesized and eva

67 ucleosome core particle (NCP) establish that methyl groups at 5mC and 6mA positions are, in general,

68 n of the pyrimidine, so each of them has two methyl groups at nucleotide positions 1 and 5 from the 5

69 trans-AT PKSs is their ability to introduce methyl groups at positions beta to the thiol ester in th

70 polysaccharide type 5 equipped with capping methyl groups at the points of propagation of the polysa

71 tect linear peptides by attaching prenyl and methyl groups at their free N- and C-termini.

72 onstration of the AlkB proteins to oxidize a methyl group attached to carbon, instead of nitrogen, on

73 es because it has a 7-[[methoxy(methyl)amino]methyl] group attached at the C7 position of ring D.

74 hen compared to the analogous dye containing methyl group away from donor.

75 nated and has to move out of the cavity as a methyl group before the hydrides can be formed.

76 hinge on the ability to distinguish a single methyl group between two histone variant isoforms and th

77 Model complexes with platinum or methyl groups bound to the nitrogen were synthesized.

78 AM and the abstraction of hydrogen from this methyl group by 5'-deoxyadenosyl radical that initiates

79 onbridging phosphate oxygens at A2662 with a methyl group by the introduction of a methylphosphonate

80 hylation states are created by deposition of methyl groups by multiple complexes of histone lysine me

81 TMD interactions, demonstrate that a single methyl group can dictate specificity, and define the min

82 inding sites and show how the orientation of methyl groups can trigger the drying of non-polar pocket

83 thodology was used to compile and validate a methyl-group carrier database (MGDB) including folate, c

84 investigating potential associations between methyl-group carrier intakes and risk or prognosis of ca

85 Balance of labile methyl groups (choline, methionine, betaine, and folate)

86 ind 5mC in the syn-conformation, placing the methyl group comparable to 3-methylcytosine, the prototy

87 Choline, a primary dietary source of methyl groups, converts Hcy to methionine and reduces ag

88 without the enzyme that can efficiently add methyl groups de novo.

89 n of increasing amounts of TM-bdc, with four methyl groups decorating the benzene dicarboxylate linke

90 , reactions with CdMe2 produce surface bound methyl groups (delta = 0.4 ppm, 0.04-0.22 nm(-2)) that p

91 folate, B-6, and total B-12 are key for the methyl group-dependent endogenous synthesis of phosphati

92 her yields than those attributable to the C5-methyl group deprotonation in NMe-1.

93 We noted that the methyl group derives from SAM, with cobalamin acting as

94 The appended methyl group derives from SAM; however, the enzyme also

95 omologs of Escherichia coli AlkB removes the methyl group directly.

96 We find that hydrophobic dehydration of the methyl group does not contribute to the binding free ene

97 diated by (1)H-(13)C cross-relaxation within methyl groups due to reorientation dynamics, and results

98 e 'magic methyl effect', the installation of methyl groups-especially adjacent (alpha) to heteroatoms

99 se analogues, one without and one with a C26-methyl group, exhibit remarkably different protein kinas

100 Oxidative C-H hydroxylation of methyl groups, followed by their removal from DNA, RNA o

101 ides that differ by the position of a single methyl group for both mono- and dimethylated variants.

102 d 1-carbon transfer are the major sources of methyl groups for 1-carbon metabolism.

103 nent of 1-carbon metabolism, which generates methyl groups for DNA methylation.

104 (SAM), which is the major cellular donor of methyl groups for protein modification.

105 thymidylate synthesis, and the provision of methyl groups for synthetic, regulatory, and epigenetic

106 It removes the 14alpha-methyl group from cyclized sterol precursors by first fo

107 rase (HNMT) inactivates HA by transferring a methyl group from S-adenosyl-l-methionine to HA, and is

108 the KMT family catalyze the transfer of the methyl group from S-adenosylmethionine (SAM) to lysine r

109 Ma) and NifB(Mt) can catalyze the removal of methyl group from SAM and the abstraction of hydrogen fr

110 ome substrates to catalyze the transfer of a methyl group from SAM to the epsilon-amino group of hist

111 We propose that rotation of the N(6)-methyl group from the preferred syn conformation in the

112 rase 1 (NTMT1) catalyzes the transfer of the methyl group from the S-adenosyl-l-methionine to the pro

113 The NirE enzyme catalyses the transfer of a methyl group from the SAM to uroporphyrinogen III and se

114 active allele in combination with removal of methyl groups from CpG dinucleotides.

115 et2) is an epigenetic regulator that removes methyl groups from deoxycytosine residues in DNA.

116 mily of histone demethylases that remove tri-methyl groups from H3K9 and H3K36.

117 These enzymes catalyze the transfer of donor methyl groups from the cofactor S-adenosylmethionine to

118 -ketoglutarate-dependent demethylases remove methyl groups from tri- and dimethylated lysine 4 of his

119 Polycomb-mediated gene silencing by removing methyl groups from trimethylated histone H3 lysine 27 (H

120 f-function (GOF)], apparently by placing its methyl group further inward and receiving stronger water

121 The nitroxides are designed to have the methyl groups further away from the N-O spin site to dec

122 MethylFLYA confidently assigns 488 methyl groups, i.e. 80% of those with NOESY data.

123 ii) a similar cyclization with a loss of the methyl group; (iii) a tandem process of cyclization into

124 Mutation of this hydroxyl to a methyl group impedes clamp binding and opening, DNA bind

125 iguously to an electronic effect by the para-methyl group in 1b, which increases the contribution of

126 Several naphthalene compounds containing a methyl group in a 1,8-relationship to a metal-complexed

127 e that highlights the importance of a single methyl group in biasing the conformation in the acyclic

128 cid (AABA), a cysteine analogue containing a methyl group in place of the sulfhydryl group present in

129 a DNA element with every pyrimidine having a methyl group in the 5-carbon position (thymine or 5-meth

130 enyl ring is slightly closer to the naphthyl methyl group in the complexes than in their metal-free c

131 w that a minor change, the introduction of a methyl group in the delta position, results in a signifi

132 e created new amino acids that incorporate a methyl group in the gamma-position of the stapling amino

133 er-energy anti conformation, positioning the methyl group in the major groove.

134 labeling studies confirmed the origin of the methyl group in the methanol product is the iridium-meth

135 rom the beta-position of the thiazole to the methyl group in the product.

136 hat 5-methylcytosine and thymine both have a methyl group in the same position, 5-carbon of the pyrim

137 ular hydrogen atom abstraction from benzylic methyl groups in 3, followed by intermolecular hydrogen

138 NMR spin relaxation studies of labeled methyl groups in both DNA and the H2B histone protein co

139 l micronutrients involved in the donation of methyl groups in cellular metabolism.

140 E isomers depended on number and position of methyl groups in the chroman ring.

141 ric protection of the radicals by additional methyl groups in the pendant group.

142 possesses four mPEG-3 groups replacing four methyl groups in the tert-butyl groups at the 3- and 6-p

143 widespread chemical shift perturbations for methyl groups in Z AAT (E342K).

144 The shielding effect of a methyl group incorporated in the coumarin derivative nea

145 isotope effect), whereas deuteration of the methyl group induces a normal secondary isotope effect.

146 voring the desired atropisomer in which this methyl group interacts with the S2 pocket of FVIIa.

147 le method for the sequential conversion of a methyl group into a fully substituted carbon center rema

148 enzo[g]indoles with [1,3] migration of the N-methyl group into the newly formed pyrrole ring; (ii) a

149 ormational constraint does indeed direct the methyl group into the S2 pocket as designed.

150 dAMP-bound human MTH1, revealing that the N6-methyl group is accommodated within a hydrophobic active

151 s an epigenetic modification of DNA, where a methyl group is added at the fifth carbon of the cytosin

152 ereomer is observed when the chiral benzylic methyl group is introduced.

153 The acetyl methyl group is lost during the reaction as methane.

154 tion state (TS) in which the transfer of the methyl group is rate limiting.

155 The steric effect exerted by the methyl group is responsible for the nonplanar arrangemen

156 f substituents on the signal of the naphthyl methyl group is small but discernible in the uncomplexed

157 al theory calculations indicate that the SAM methyl group is sterically constrained in complex with N

158 et binding precedes DNA binding and AdoMet's methyl group is then transferred to an adenine within th

159 Here we demonstrate that the methyl group is transferred to a precursor-associated su

160 he distance between the nitroxide moiety and methyl groups is effective in lengthening Tm at T > 70 K

161 Quantitatively, a significant use of labile methyl groups is in the production of phosphatidylcholin

162 ored by observing the (1)H NMR signal of the methyl group located in the shielding zone of the ring.

163 To aid this process, several Ile methyl groups located in different binding sites of the

164 eplacing the transferring hydrogen atom by a methyl group makes the substrate inactive and hence conf

165 ly improved choline and other markers in its methyl group metabolism pathway.

166 Solvation of the fibrils does not affect methyl group motions within the hydrophobic core of indi

167 also show that incorporation of a trifluoro-methyl group ( N(CF(3))Rpe) rather than a methyl group (

168 o synthesize new proteins and to provide the methyl groups needed for the methylation of RNA and DNA

169 isms by which these unactivated atoms obtain methyl groups nor the actual methyl donors are conserved

170 ro-methyl group ( N(CF(3))Rpe) rather than a methyl group ( NRpe) at the alpha-carbon of a monomer gi

171 acking motif with the electron-poor ammonium methyl groups occupying the electron-rich cavity of the

172 howed that inversion of configuration at the methyl group occurs when the chiral toluenes react with

173 are ascribable to deprotonation from the C5-methyl group of 1 are observed.

174 side chain of Glu446 is known to contact the methyl group of 5-methylcytosine (5mC) or thymine (5-met

175 the conjugation of a glyceryl moiety to the methyl group of 5mC through a carbon-carbon bond, result

176 The methyl group of 6-methylazulene was then used as a synth

177 vorans DSM 12444 is found to hydroxylate the methyl group of a range of methylcubane substrates conta

178 iD is a radical SAM enzyme that converts the methyl group of BChlide c or d into the formyl group of

179 The methyl group of dTMP apparently clashes with a highly co

180 and 2 equiv from C-H bond activation of one methyl group of each of the isopropyl groups at the 2- a

181 Perfluorination of the terminal methyl group of ethanol is found to enhance the disrupti

182 ted from (-)-epicatechin carbocation and the methyl group of methanol.

183 ent modification at a C(sp(3))-H bond in the methyl group of N6-methyl deoxyadenosine and N6-methyl a

184 nteraction between the phenylalanine and the methyl group of pyruvate.

185 ynaphthalen-2-yl)butanoic acid (in which the methyl group of R-naproxen was replaced by an ethyl grou

186 It transfers the methyl group of S-adenosylmethionine (SAM) to catalyze t

187 Mutagenesis of three residues near the methyl group of SAM and the nitrogen atom of the alkaloi

188 are within a short distance of the incoming methyl group of SAM for a direct methyl transfer during

189 e proximity to and in line with the incoming methyl group of SAM-would allow some SET domain proteins

190 e of SAM1 and the other two hydrogens of the methyl group of SAM2 appear in the methylated product.

191 show that a hydrogen is transferred from the methyl group of SAM2 to the 5'-deoxyadenosine of SAM1 an

192 Activation of the central methyl group of the ligand affords the diiron mu-carbyne

193 horizontal lineNTol species deprotonates the methyl group of the NacNac ligand.

194 addition to Sc horizontal lineNimide) with a methyl group of the NacNac(NMe2) ligand forming {MeC(NC6

195 oline's aliphatic cyclic structure and the 5-methyl group of the pyrimidine (5mC or T).

196 for radical-mediated C-C bond formation; the methyl group of toluene is positioned between fumarate a

197 toluene metabolism by adding fumarate to the methyl group of toluene to yield (R)-benzylsuccinate.

198 tention or inversion of configuration at the methyl group of toluene, we synthesized both enantiomers

199 m Apc(ko-liv) mice incorporated radiolabeled methyl groups of choline into phospholipids and DNA.

200 ith selective isotope labeling of the delta1 methyl groups of isoleucine side chains demonstrates tha

201 n 10(2) and 10(5) s(-1)) are observed in the methyl groups of isoleucine, leucine, and valine.

202 to probe the reorientation of the isopropyl methyl groups of l-leucine at the air-water interface.

203 cysteine due to reduced capacity to sink the methyl groups of SAM.

204 omplex with methylated DNA revealed that the methyl groups of the 5mCpA/TpG make van der Waals contac

205 ate NMR experiments to assign the side-chain methyl groups of the 64-kDa Mre11 nuclease and capping d

206 is enforced by the steric clash between the methyl groups of the arene ligand and the phenyl rings o

207 acycles governed by steric repulsion between methyl groups of the hydrocarbon chain of the cleaved ar

208 MR relaxation dispersion measurements of the methyl groups of the Ile, Leu, and Val residues at two s

209 cribed as partitioned into strips lined with methyl groups of the Me(2)pyzH(+) cations and strips fea

210 Methyl groups of thymine acts as a steric block, relocat

211 Specifically, we investigated the methyl groups of two leucine residues that belong to the

212 a) comprising a total of 708 isotope-labeled methyl groups, of which 612 contribute NOESY cross peaks

213 The methyl group on (C5Me5)3ThMe can be removed with [Et3NH]

214 ffering only by the presence or absence of a methyl group on the alpha-carbon, (S)-2-amino-7-[(18)F]f

215 pulsive force and presence of the additional methyl group on the backbone.

216 thylation method was employed to install the methyl group on the benzene ring.

217 A dye containing methyl group on the donor side exhibited blue shift in a

218 but also is influenced by the position of a methyl group on the monoterpene ring.

219 y to overcome this obstacle is to remove the methyl group on these modified bases prior to cDNA synth

220 traints show that the interaction energy for methyl groups on homochiral molecules differs significan

221 ether length, and the presence of isoprenoid methyl groups on one or both lipid tails.

222 The propargyl alcohol and the two terminal methyl groups on the olefinic unit shape the cyclization

223 tocopherol, differ in number and position of methyl groups on their chromanol head group.

224 Incorporation of a methyl group onto a macrocyclic FVIIa inhibitor improves

225 l cofactor that during catalysis transfers a methyl group originating from S-adenosyl-l-methionine.

226 ous in the MRC and reveal the role of Fhs in methyl group oxidation in R. pomeroyi.

227 ed set of genes encoding the upper branch of methyl group oxidation to CO2 as well as membrane-bound

228 , MG often solvates with both the ketone and methyl groups parallel to the water interface.

229 adopts a rotated conformation in which the 5-methyl group points into the minor groove, rather than t

230 he rigid compounds also suggested that the 3-methyl group present in compound 1 type antagonists may

231 with robust strategies for incorporation of methyl-group probes of structure and dynamics into the p

232 substitution at a bridgehead position with a methyl group produced a quadricyclane that thermally rev

233 Isotopically labeled methyl groups provide NMR probes in large, otherwise deu

234 Binding depends on pyrimidine 5' methyl groups provided by thymine and requires adjacent

235 According to IR and solid-state NMR, the methyl group remains intact, and does not evolve spontan

236 eals that when MG is in the trans state, the methyl group repels interfacial water to maintain the pl

237 spectively), proceeds via oxidation of the N-methyl group, resulting in the release of formaldehyde.

238 the hydration shell structure of fluorinated methyl groups results from a delicate balance of solute-

239 phosphines; introduction instead of a single methyl group reveals the first stereospecific synthesis

240 The methyl groups rigidize the ice-binding site, slow the wa

241 n of PAAs was related to the position of the methyl group, showing the same isomer specific preferenc

242 Second, we showed that PTP1B (13)C-methyl group side chain fast time-scale dynamics and (15

243 with an ethyl group or adding a second 1'-N-methyl group significantly reduced interaction with alph

244 nicotinamide (vitamin B3), which serves as a methyl group sink.

245 With data from six methyl groups, Spearman's correlation coefficient of the

246 unmodified or possessing single or multiple methyl group substituents on each of its four -CH(2)-CH=

247 Benzylamine compounds with methyl group substitution on the charged amine or with e

248 depend, as predicted by calculation, on its methyl group substitution pattern, making 3 by some way

249 phoethanolamine methyltransferases add three methyl groups successively to their substrate to produce

250 abolism in ESAM and support consideration of methyl-group supplementation in ESAM.

251 er, these results indicate that removal of a methyl group switches PK11195 from a potent antagonist o

252 ns 1 and 5 from the 5 end, resulting in four methyl groups symmetrically positioned in duplex DNA.

253 jos-Parrish ketone isomers with a transposed methyl group (termed "iso-Hajos-Parrish ketones") would

254 tion is predicted to be more in favor of the methyl group than the methylene of the pentyl chain, in

255 MethylFLYA assigns significantly more methyl groups than alternative algorithms, has an averag

256 ing-tunneling microscopy showed well-ordered methyl groups that covered nearly all of the surface.

257 only in the presence and/or position of the methyl groups that encircle the portal to their non-pola

258 ated MethylFLYA method for the assignment of methyl groups that is based on methyl-methyl nuclear Ove

259 Due to the benefit of methyl group, the dyes restrained the formation of aggre

260 rsible synthesis of acetyl-CoA from CO and a methyl group through a series of nickel-based organometa

261 at is involved in subsequent transfer of its methyl group to 5 or 8, H2O, and other nucleophilic comp

262 Adding a methyl group to a cytosine base locally modifies the str

263 al SAM enzyme catalyzing the conversion of a methyl group to a t-butyl group.

264 Covalent addition of a methyl group to adenosine N(6) (m(6)A) is an evolutionar

265 very low subsequent transfer of this labeled methyl group to D3-PC indicated that liver PEMT activity

266 nsecutive hydroxylation reactions of the C-7 methyl group to form a geminal diol intermediate, which

267 mediated hydrogen-atom abstraction at the N6-methyl group to form an alpha-amino radical.

268 only catalyzes sequential methylations of a methyl group to form ethyl and isopropyl groups but rema

269 cterized protein that oxidizes the pyocyanin methyl group to formaldehyde and reduces the pyrazine ri

270 and 5'-deoxyadenosine and the transfer of a methyl group to l-valine residue.

271 Methyltransferases add a methyl group to mRNA while demethylases remove methyl gr

272 ine resulted in the transfer of 1 deuterated methyl group to S-adenosylmethionine.

273 Subsequent steps entail conversion of the 1-methyl group to the 1-(dimethoxymethyl) unit and acid-ca

274 generated through the covalent addition of a methyl group to the fifth carbon of cytosine, is the mos

275 common mRNA modification, the addition of a methyl group to the N(6) position of adenosine (m(6)A),

276 e peak area of the valine/isoleucine/leucine methyl groups to an external, certified, small-molecule

277 ) controls one-carbon metabolism by donating methyl groups to biochemical building blocks, DNA, RNA,

278 novo DNA methyltransferases DNMT3a/3b adding methyl groups to CG dinucleotides in the hypomethylated

279 DNMT3a/3b can add methyl groups to daughter strands after each cycle of DN

280 methionine ratio, decreasing the transfer of methyl groups to DNA and RNA.

281 on affects chromatin through the addition of methyl groups to lysine or arginine residues of histones

282 Post-translational addition of methyl groups to the amino terminal tails of histone pro

283 The importance of several methyl groups to the potency of the inhibitors is highli

284 ) kinetic isotope effects at the transferred methyl group, together with (1)H3/(3)H3 binding isotope

285 ivities by functionalization of enantiotopic methyl groups under mild conditions.

286 ble under these reaction conditions, but its methyl group undergoes facile H/D exchange (k(3) = 0.046

287 es when an H-bonding moiety is replaced by a methyl group was contrasted.

288 rine substitution, while the effect of the 4-methyl group was negligible.

289 on permeation, such that no ion possessing a methyl group was permeant.

290 In addition, the methyl group was the best substituent, followed by the a

291 eriments performed on selectively deuterated methyl groups, we probed the 3-fold symmetric and 2-fold

292 laxation performed on selectively deuterated methyl groups, we probed the dynamics in the threefold s

293 d baseline circulating glycoprotein N-acetyl methyl groups were associated with longitudinal risk of

294 The angular methyl groups were attached by electrophilic cyclopropan

295 e of the incident light, indicating that the methyl groups were bonded directly atop surface Ge atoms

296 er an n-propyl or a phenyl group alongside a methyl group, were synthesized and obtained in a high pu

297 adicals produced from H abstraction from the methyl group, which also gives OH radicals as co-fragmen

298 m (1)H/(13)C NMR probes at isoleucine delta1 methyl groups, which facilitated (1)H/(13)C methyl TROSY

299 ne groups investigated here are analogues to methyl groups, which provides the opportunity to transfe

300 e, we study how AP-1 and Zta recognize these methyl groups within their cognate response elements.