ライフサイエンスコーパス: mice

1 cycle in nutrient-sensitive and -insensitive mice.

2 hotopic xenograft model in immunocompromised mice.

3 ropoietin levels in the kidneys of KS-tg/OVE mice.

4 ding but are completely absent in TSG-6-null mice.

5 ls, and an increase in apoptotic cells in KO mice.

6 in metastatic tropism when xenografted into mice.

7 to vigorous seizures and a quick death in KO mice.

8 terleukin-27 (IL-27) is elevated in neonatal mice.

9 disease index of the experimental colitis in mice.

10 MPKbeta1 abundance in the liver of E4bp4-LKO mice.

11 intestine of Hnf4alphagamma(DKO) and control mice.

12 ible retinal blood flow measurement in adult mice.

13 d inflammatory programs in WT versus IRF3-KO mice.

14 exacerbated fibrotic profile of Map3k8 (-/-) mice.

15 wound healing and nerve density in diabetic mice.

16 luripotency and ability to generate chimeric mice.

17 hway in bone marrow and BM-MSC of DeltaNC16A mice.

18 o promote sensitization to inhaled peanut in mice.

19 umin (PV) GABAergic interneurons of Ahnak KO mice.

20 hickening in comparison to Aip+/, Prkar1a+/- mice.

21 pathogenic PBX1 variants in both humans and mice.

22 r (D2R) and cause psychotic-like features in mice.

23 used in in vivo immunization experiments in mice.

24 ity compared with Nf1(flox/flox);PostnCre(+) mice.

25 eic skin grafts in young RAG2(-/-) recipient mice.

26 under normal and inflammatory conditions in mice.

27 susceptible to superinfection than wild-type mice.

28 liver injury and sinusoidal ischemia in SCD mice.

29 mation, was also prevented in EW RV-infected mice.

30 promoted cholesterol excretion in Abcg8(-/-) mice.

31 from day 3 to day 14 compared with untreated mice.

32 the KI, KI;Fatp4 (+/-) , and KI;Fatp4 (-/-) mice.

33 and partial sciatic nerve ligation models in mice.

34 cial regulator of heart valve development in mice.

35 lmonary vaso-occlusions in End.TGFbetaRII-KO mice.

36 of CDI in human microbiota-associated (HMA) mice.

37 al tumorigenesis in 11G5-infected Apc(Min/+) mice.

38 g the development of diet-induced obesity in mice.

39 These changes were not seen in MIOX-KO mice.

40 se that triggers episodic motor paralysis in mice.

41 on and activation during Kras-driven PDAC in mice.

42 responding reduction in ethanol intake in KO mice.

43 and extracellular electrophysiology in awake mice.

44 ic sutures in the pancreatic tail of C57/Bl6 mice.

45 es not alter viability of Mtb in vitro or in mice.

46 ution in the plasma compartment in humanized mice.

47 not improve splenomegaly in beta-thalassemic mice.

48 lenge in 33% of nanoformulated CCL21-treated mice.

49 duced in the skin of doxycycline-treated MFS mice.

50 as attenuated suppression of tumor growth in mice.

51 he retina of streptozotocin-induced diabetic mice.

52 ociated with improved glucose homeostasis in mice.

53 ased survival relative to wild-type knock-in mice.

54 l coping mechanisms and stress resiliency in mice.

55 produced in the endocrine pancreas of obese mice.

56 he BCL2 family, in intestinal homeostasis in mice.

57 esponses to predator odor in alcohol-exposed mice.

58 ted with thinner cortical bone in adult male mice.

59 ous administration to female and male BALB/c mice (10 animal/sex/group) along with their human blood

60 colocalize with Kiss1(hrGFP) in prepubertal mice, ~30% of GHRH neurons coexpressed both reporter gen

61 WT and FATP2-null (Fatp2 (-/-)) mice (5 weeks) were maintained on a standard chow diet f

62 om wild type (WT) and col4alpha5 knockout AS mice, a hereditary disorder characterized by progressive

63 and function are clearly demonstrated in RTT mice, a particular mode of inhibition, tonic inhibition,

64 these data suggest that in dopamine-depleted mice abnormally correlated and temporally offset PV GPe

65 Results showed that KO mice accumulated high concentrations of upstream lysine

66 at short-term high-fat-diet (HFD) feeding of mice activates prepronociceptin (PNOC)-expressing neuron

67 he residence time of rhDNase in the lungs of mice after pulmonary delivery while preserving its full

68 r SAA1 and SAA2 production in Th17-deficient mice after stress.

69 nificantly between susceptible and resilient mice after the first defeat session and continue to dive

70 Mice also acquired operant self-stimulation of thalamost

71 Col6a1(-/-) mice also displayed multiple airway changes, including i

72 the HSC clonal repertoire in hematochimeric mice, although engrafted edited clones preserve multilin

73 in Plasmodium berghei ANKA-infected C57BL/6J mice, an experimental CM model.

74 ion in primary somatosensory cortex of young mice and behavioral hyperactivity in the mice at one min

75 Strikingly, mice and flies lacking functional autophagy develop earl

76 In BCG-vaccinated mice and guinea pigs, metformin enhances immunogenicity

77 e-associated B cells [ABCs]) is increased in mice and humans with infections or autoimmune diseases.

78 17R signaling is essential to prevent OPC in mice and humans, but the individual roles of its ligands

79 have numerous shared characteristics between mice and humans.

80 ed with fasting plasma glucose in both obese mice and humans.

81 mic lymphatic vessel development in prenatal mice and it is critical for their survival postnatally.

82 nder UF cell culture conditions or in Balb/C mice and led to an over 2-fold increase in CTC attachmen

83 In both mice and nonhuman primates, cocktails of three de novo-d

84 sternomastoid (STM) muscles from SOD1(G37R) mice and performed Ca(2+)-imaging to monitor PSC activit

85 cally similar tendons were different between mice and rats.

86 d glucose tolerance in D734A INSR-expressing mice and reduced hyperinsulinemia in both S350L and D734

87 ly promotes GBM tumor growth and invasion in mice and significantly reduces the survival time of the

88 CO1 were similar in mitochondria from YAC128 mice and their wild-type littermates as well as in mitoc

89 xpressed at very low levels in the wild-type mice and were significantly upregulated in the mutant mi

90 n injected into mammary fat pad of syngeneic mice, and demonstrated synergy when combined with anti-P

91 sconnect in biotin levels between humans and mice, and explains the failure of potent biotin biosynth

92 tion of Nrf2 causes osteopenia in Keap1(-/-) mice, and Keap1(-/-) osteoblasts have significantly less

93 f sex-biased brain development in humans and mice, and shed light on the consistency, candidate cause

94 is markedly higher in germ-free than in SPF mice, and winner B cells in germ-free germinal centres a

95 erglycemic, but mildly insulin-resistant, KK mice; and hyperglycemic and markedly insulin-resistant K

96 However, CD163(-/-) mice are highly susceptible to S aureus infections, demo

97 ARalpha, and we demonstrate that Ppara (-/-) mice are less susceptible to superinfection than wild-ty

98 We found that mice are more likely to stay in places paired with orexi

99 we show that Syrian hamsters, in contrast to mice, are highly permissive to SARS-CoV-2 and develop br

100 ignificantly increased in diet-induced obese mice as compared with controls.

101 SF-PreCon markedly reduced MI/R injury in DM mice, as evidenced by improved cardiac function (increas

102 on in ventricular cardiomyocytes from C-dnO1 mice, associated with blunted Pyk2 signaling.

103 production in exposed offspring and juvenile mice at age 12 and 14 days, respectively.

104 ung mice and behavioral hyperactivity in the mice at one minute after the loss of righting reflex.

105 d with alpha-syn fibrils and 20 PBS-injected mice at three timepoints (10 males and 10 females per gr

106 Mice bearing MDA-MB-231 breast cancer and FaDu head neck

107 ate the development of nephrotic syndrome in mice bearing the Asah1 podocyte-specific gene deletion.

108 CHIP-S20E knock-in mice better clear ubiquitinated proteins and are cardio-

109 In mice, both prophylactic and therapeutic RDV improve pulm

110 We found that EphA4 KO in young mice, but not older adult mice, causes defects in muscle

111 ir cells was also affected in Ca(V) 1.3(-/-) mice, but to a much lesser extent than apical cells.

112 Using two strains of mice, C57BL/6J and BALB/cJ, and deploying deep RNA-Seq c

113 Our study indicated that Dp16 mice can be a useful model to examine the pathophysiolog

114 esting that the poor stroke recovery in aged mice can be reversed via poststroke bacteriotherapy foll

115 ICH induction in male mice caused profound HN loss in the affected hemisphere.

116 tions have CTDs, and inactivation of Crkl in mice causes CTDs, thus implicating this gene as a modifi

117 EphA4 KO in young mice, but not older adult mice, causes defects in muscle function, consistent with

118 Prnp180Q/196Q mice challenged with 2 subfibrillar, non-plaque-forming

119 In our model, mice clustered in two groups displaying high or low clin

120 tic cell death in the lungs of superinfected mice compared to mice infected with S. aureus alone.

121 CL2 were decreased in lungs of superinfected mice compared with controls.

122 e found in the guts of conventionally raised mice compared with germ-free animals.

123 he brain and periphery of lipopolysaccharide mice compared with the acid-mediated [(64)Cu]Cu-c[E(4)W(

124 stemming from them in male heterozygous Q175 mice, compared to age-matched WT males.

125 we found that the urine of pristane-injected mice contained increased levels of putative markers for

126 ividual epithelial cells from healthy BALB/c mice (controls) and TxA23 mice, which have chronically i

127 tigated neural and inflammatory markers from mice deficient for ELOVL2 (Elovl2(-/-) ), the key enzyme

128 Mice deficient in Fgl2 had dysregulated Ab responses at

129 Dp16 mice demonstrated craniofacial hypoplasia, especially in

130 Twelve-month old Aip+/- mice demonstrated phenotypic and biochemical evidence of

131 Here we show that Dysf(-/-) mice develop adverse LV remodeling following I/R injury

132 Homozygous mutant mice develop lethal postnatal inflammation of the saliva

133 memory task, whereas sedentary and adol ELE mice did not.

134 tubule-specific ENaC gamma-subunit knockout mice displayed decreased claudin-8 expression, confirmin

135 Nephrotic mice displayed decreased glomerular filtration rate and

136 melanopsin-activated astrocytes in wild-type mice enhanced the firing rate of cortical neurons and ga

137 Genetically labeled mice established that L1 neurons are proprioceptors.

138 rs remained stable and similar as in control mice, even in aged animals.

139 erase (RdRP) outside the viral context (RdRP mice) exhibit constitutive, MDA5-dependent, and quantita

140 Nkx6.2-null embryos, neonates and adult mice exhibited alterations of locomotor pattern and spin

141 Resilient mice exhibited an adaptive decrease in total running, ap

142 stis-infected Mefv(M680I/M680I) FMF knock-in mice exhibited IL-1-dependent increased survival relativ

143 By contrast, trisomic mice exhibited poor memory abilities and disordered pref

144 ent, immature cDC1s in Mycl (-/-) -deficient mice exhibited reduced expression of genes that regulate

145 Additionally, IL-6-deficient asthmatic mice exhibited reduced goblet cell hyperplasia and incre

146 Despite both control and ACC2 iKO mice exhibiting a similar obese phenotype, increasing FA

147 Extracellular recordings from mice exploring real 2D arenas demonstrate that grid cell

148 t, and very few differences were observed in mice exposed to rmTBI compared to controls.

149 We have shown that transgenic mice expressing a picornavirus RNA-dependent RNA polymer

150 Mice expressing the HTLV-1 oncogene Tax, driven by the h

151 In AKT-KI(+/+) mice, expressing the pathogenic human Tau mutant (hTau-P

152 beta in human wild-type alpha-Syn transgenic mice facilitates PD pathologies and elicits motor disord

153 while on the Western-style diet compared to mice fed control bacteria and had alterations in hepatic

154 Mice fed the L lactis subsp cremoris had increased gluco

155 Electron microscopic studies performed in mice fed with cuprizone and treated with anacardic acid

156 -alpha secretion, and tissue inflammation in mice (female BALB/c strain) with an LPS-induced acute lu

157 AGE(-/-) , TLR4(-/-) and TLR4(-/-) RAGE(-/-) mice following acute exposure to cigarette smoke (CS).

158 gle-cell electrophysiology in awake behaving mice following auditory associative training.

159 ineered human APOE targeted replacement (TR) mice following repeated mild TBI (rmTBI) using a lateral

160 Knockout mice for the kisspeptin receptor, Kiss1r (Kiss1r-/-) and

161 es have suggested that estrogens may protect mice from AKI.

162 Loss of HDAC3 in macrophages safeguards mice from lethal exposure to lipopolysaccharides, but th

163 n, reduced total IgE serum levels, protected mice from passive and active IgE sensitization, and resu

164 observed in the vehicle but not in the test mice groups.

165 ype virus and found that the DUBmut-infected mice had a statistically significant reduction (P < 0.05

166 DCs from Apc(Min/+)Ffar2(-/-) mice had an altered state of activation, increased death

167 alysis showed that podocytes of the knockout mice had distinctive foot process effacement and microvi

168 Prph2K/+/Rom1+/- mice had improved rod and cone function compared with Pr

169 Normoglycemic and insulin-sensitive C57BL/6J mice; hyperglycemic, but mildly insulin-resistant, KK mi

170 Administration of FGF21 in obese mice improves defective autophagy and hepatosteatosis in

171 , A2A-Cre, or vGluT2-Cre:Ai9 male and female mice in a cocaine conditioned place preference protocol

172 PCa epithelia with CAF expanded similarly in mice in the presence or absence of docetaxel.

173 Here, we show that mice in which alpha2-Na/K ATPase is conditionally delete

174 Notably, mice in which both Nf1 and Rac1 loci were disrupted (Nf1

175 Sex differences were noted in control mice, in which female islets showed 5 selenoproteins dec

176 erefore, our anatomical findings in rats and mice indicate that the INS-PSTN network is organized in

177 were significantly upregulated in the mutant mice, indicating that pre-translational splicing defects

178 rescues cardiac defects in Xinbeta knock-out mice-indicating a functional and genetic interaction bet

179 the lungs of superinfected mice compared to mice infected with S. aureus alone.

180 ess symptoms were evident in immunodeficient mice infected with T. gondii, as associated with high ex

181 in the different levels of neurovirulence in mice infected with WNV NY99 or Eg101.

182 al MRI (fMRI), and sensory-evoked fMRI on 20 mice injected with alpha-syn fibrils and 20 PBS-injected

183 substantial during the aging of short-lived mice, is stabilized at low levels during the aging of lo

184 ient cell isolation from Ccl17(E/+) reporter mice; it also exploited both CCL17-dependent and unique

185 specific and CD11c-specific knockout ((-/-)) mice lacking AhR, respectively, in LC and Langerin(+) de

186 was elevated in the prostates harvested from mice lacking HO-1 in myeloid compartment.

187 Here, we report that mice lacking Pdcd1 (Pd1-/-) demonstrated remarkable prot

188 Moreover, mice lacking PI3Kalpha and PI3Kdelta in Treg cells devel

189 Here we show, by analyzing Batf3(-/-) mice lacking the CD103(+) conventional dendritic cell ty

190 in Speg-KO mice was compared with that of WT mice, leading to the identification of similar abnormali

191 ound that global genetic ablation of EHD2 in mice leads to increased lipid droplet size in fat tissue

192 The Ash1l(+/-) mice manifested tic-like behaviors and compulsive behavi

193 hen nesting material is provided, individual mice may be experiencing thermal stress.

194 es of male and female TDP-43(Q331K) knock-in mice may help to unravel the mechanisms underlying sex-s

195 Interestingly, genetic ablation of TRPML1 in mice (Mcoln1 (-/-) ) induces a hyperdistended/hypertroph

196 Compared with nontransgenic wild-type mice, mice with neuronal Mfn2 overexpression also exhibi

197 C57BL/6J female mice (n = 18) were first treated with antibiotics for 4

198 Ten weeks old male C57BL/6 mice (n = 9) underwent left anterior descending (LAD) co

199 In mice, not only was TFR1 increased, but FPN was surprisin

200 differentiation were found in gut mucosa of mice nursed by mothers exposed to D pteronyssinus compar

201 We find that, in NF1 mice of both sexes, inhibition increases strongly during

202 d in the calyx of Held terminals of juvenile mice of either sex during high-frequency spiking.

203 inflicted substantial DG-specific damage in mice of either sex either by diphtheria toxin-based abla

204 ts with synaptosomes from Slc38a1 knock-down mice of either sex further support its role as a D-serin

205 S pressure, and the time for sacrificing the mice post-FUS (T(lag2)).

206 as well as small interfering RNA studies in mice primary macrophages, showed that the transcriptiona

207 t junction protein claudin-5 (cldn5) in male mice, promoting passage of circulating proinflammatory c

208 newly hyperglycemic non-obese diabetic (NOD) mice, protecting the insulin-producing beta-cells from d

209 We further show that GATIR mice provide an ideal tool for noninvasive monitoring of

210 MHV infection in mice provides an efficient cause-effect experimental mod

211 te group of 15.5 to 17 months of age C57BL/6 mice received a diet containing an Nrf2 inducer (Oltipra

212 Over a period of repeated training sessions, mice received either paired trials of a tone coterminati

213 HET mice receiving CAF (plasma CAF 893 ng/ml) have significa

214 attenuate acute kidney injury in transgenic mice receiving contrast material.

215 Administration of AFSE to diabetic mice reduced total cholesterol, triglycerides, LDL-chole

216 tion of GABAergic and neuronal activation in mice regardless of cirrhosis compared with those from he

217 t is deleted in gut using Villin-Cre, female mice remain healthy despite significant X-autosome dosag

218 on of an AAV8-ZAP-70 vector into ZAP-70(-/-) mice resulted in a rapid thymocyte differentiation assoc

219 vasoconstrictors in arteries from Jak2V617F mice resulting from a disturbed endothelial NO pathway a

220 has shown that germline deletion of Grb14 in mice results in cardiac hypertrophy and impaired systoli

221 tumors in sunitinib-treated EpsilonC-betaKO mice showed a marked decrease in microvessel density, an

222 During both NREM and REM sleep, mice showed large increases in cerebral blood volume ([H

223 amples from post-FMT patients to colonize GF mice shows a direct effect of fecal microbiota independe

224 nversely, administration of IL-33 in healthy mice suppressed erythropoiesis, decreased hemoglobin exp

225 However, in AD mice, SWR-DW and spindle-DW coupling were impaired.

226 we develop bioluminescent circadian reporter mice that are Cre dependent, allowing the circadian prop

227 Mice that are heterozygous for the missense mutation sho

228 g is corroborated in stress-susceptible male mice that have undergone chronic social defeat stress, a

229 Mice that lack TLR9 are deficient in both exercise-induc

230 We performed studies with male C57BL/6 mice that persistently replicate HBV (genotype D, seroty

231 ntrinsically photosensitive RGCs (ipRGCs) in mice that release the inhibitory neurotransmitter gamma-

232 We show in awake behaving mice that the onset of tremor is coincident with rhythmi

233 nce, including changes in the microbiome, in mice that underwent colorectal resection.

234 demyelination model in young and middle-aged mice, the latter group developed greater acute axonal an

235 been extensively studied in rats instead of mice, there is renewed interest in the anatomy of the mo

236 SNs) in the ventral striatum of D2R knockout mice, this mutant restored basal locomotor activity and

237 aortic ultrastructure and skin dermis of MFS mice through immunohistochemical evaluation and quantifi

238 Switching mice to a high lysine/low PN diet led to vigorous seizur

239 yloid precursor protein (APP) knock-out (KO) mice to assess the effects of Abetaos on glutamatergic t

240 used an activity-dependent tagging system in mice to determine the epigenetic state, 3D genome archit

241 ncreased levels of IL-27 predispose neonatal mice to more severe infection during Gram-negative sepsi

242 the memory Th17 compartment predispose aged mice toward the development of severe corneal epithelial

243 Consistent with this hypothesis, mice transplanted with T-cells co-expressing NOTCH1 and

244 NOTCH1 and NRARP develop leukemia later than mice transplanted with T-NOTCH1 cells.

245 Mice treated with PLX5622 had a significantly faster dec

246 pha neurons in the arcuate nucleus of female mice undergoes a shift in phenotype, from GHRH to Kiss1,

247 Female C57BL/6J mice underwent dorsal wounding following an established

248 licker stimulation and systemic hyperoxia in mice using a laser speckle flowgraphy (LSFG-Micro).

249 Critically, disruption of GAL5.1 in mice using CRISPR genome editing significantly reduced G

250 30 days in wild-type and Msx2 knock-in Swiss mice using Porphyromonas gingivalis infected ligatures.

251 ion of lipid cacostasis in the CNS of normal mice was associated with ALS-like lipid pathology, astro

252 er, elevated cochlear adenosine in untreated mice was associated with enhanced Adora2b gene expressio

253 esponse to skeletal muscle injury in Speg-KO mice was compared with that of WT mice, leading to the i

254 e enhanced monocyte apoptosis in CMH-treated mice was paralleled by increased numbers of HIF-1alpha+

255 mation observed in p53(5KR/5KR) and p53-null mice was suppressed upon the treatment of the mTOR inhib

256 r in combination with orthogonal analyses in mice, we detected four main pathways that contribute to

257 ling single CA2/CA3 neurons in freely-moving mice, we explored whether and how burst propensity relat

258 Following angiotensin II infusion in mice, we found that an affinity matured nanobody antagon

259 In the NAc of helpless mice, we found that higher expression of CRY is associat

260 viral population dynamics in orally infected mice, we produced over 100 CVB3 clones harboring nine un

261 As compared with WT mice, we show that the activity of IL-13 is dramatically

262 and Prox1-CreER(T2) ;Cx43(fx/fx) ;Cx37(-/-) mice, we tested our method on lymphatic valves displayin

263 C57BL/6 mice were administered with UA (10 mg/body weight) for 1

264 tized wild-type and CD8-deficient (CD8(-/-)) mice were challenged with allergen.

265 Additional GF mice were colonized with stool from controls (Ctrl-Hum)

266 ways in the uterine tissues of G12D and G12V mice were identified using RNA sequencing and reverse-ph

267 Fingolimod-treated EAE mice were imaged with (18)F-FAC PET to assess if this ap

268 Eight to 12 weeks later, mice were immunized twice with a mixture of adjuvanted H

269 racing technique, nulliparous female C57BL/6 mice were injected unilaterally with biotinylated dextra

270 In contrast, CT neurons in mice were mostly located in Layer 6 across all areas.

271 d that lithium-induced behavioral changes in mice were phenocopied by modulation of the circadian sys

272 T cells from infant mice were predominantly immature, insensitive to RORgamm

273 Mice were then given diethylnitrosamine and carbon tetra

274 ter establishment of autoimmune myocarditis, mice were treated with the immunoproteasome inhibitor ON

275 Transplanted mice were treated with vehicle or di-n-butyl-phthalate (

276 glycemic and markedly insulin-resistant KKAy mice were used for ozone exposure studies.

277 metastasis and increased overall survival of mice when injected into mammary fat pad of syngeneic mic

278 derived from lipodystrophic A-ZIP transgenic mice, which have a genetic block in adipogenesis.

279 rom healthy BALB/c mice (controls) and TxA23 mice, which have chronically inflamed stomachs with meta

280 IL-13 is dramatically augmented in SP-A(-/-) mice, which have significantly increased neutrophil and

281 In Emu-Myc mice, which model the MYC/IGH chromosome translocation i

282 er varicosities developed in acutely treated mice while more varicosities resolved in mice with delay

283 iring patterns are largely absent in rTg4510 mice, while head-direction tuning remains largely intact

284 Mice with a Purkinje-cell-specific knockout (KO) of the

285 Notably, treatment of infected wild-type mice with apoptotic cells significantly increased GM-CSF

286 ted mice while more varicosities resolved in mice with delayed treatment.

287 We generated and subjected mice with EC-AGO1 deletion (EC-AGO1-knockout [KO]) and t

288 esistant NSCLC cells (IC(50) = 17 nM) and in mice with H1975 xenograft tumor.

289 n amyloid precursor protein knockin (APP-KI) mice with impaired spatial memory.

290 Mice with myeloid-specific gene deletion of Traf3ip3 hav

291 Compared with nontransgenic wild-type mice, mice with neuronal Mfn2 overexpression also exhibited al

292 roles of the two receptor populations using mice with picrotoxin resistance engineered into receptor

293 characterize FUSIN drug delivery outcome in mice with regard to its dependency on several critical e

294 Treatment of diabetic mice with the NFAT blocker A-285222 reduced NFATc3 nucle

295 gnificantly reduces the survival time of the mice with tumor.

296 tes progression of CKD beyond MRE therapy in mice with type 2 diabetes.

297 if structure informs function, we generated mice with zG-specific expression of GCaMP3 and imaged zG

298 treat lethal viral respiratory infection in mice, with increased maturation of dendritic cells and t

299 stem and progenitor cells in naturally aged mice without causing severe thrombocytopenia.

300 rom global Zip14 knockout (KO) and wild-type mice (WT).